Guide to the Human Genome
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Search of human proteins with 226059133

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]       663   0.0  
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]       663   0.0  
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]       593   e-170
gi|226246682 prostaglandin reductase 2 [Homo sapiens]                 203   2e-52
gi|226246680 prostaglandin reductase 2 [Homo sapiens]                 203   2e-52
gi|22748929 prostaglandin reductase 2 [Homo sapiens]                  203   2e-52
gi|28557745 zinc binding alcohol dehydrogenase domain containing...   100   2e-21
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                 68   1e-11
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                  68   1e-11
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       60   2e-09
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       60   2e-09
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 60   2e-09
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    58   1e-08
gi|197927207 crystallin, zeta isoform c [Homo sapiens]                 57   3e-08
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    56   4e-08
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    55   9e-08
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           52   6e-07
gi|41872631 fatty acid synthase [Homo sapiens]                         49   6e-06
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     35   0.12 
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...    31   1.7  
gi|4502119 amine oxidase, copper containing 3 precursor [Homo sa...    31   1.7  
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...    30   3.0  
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...    30   3.9  
gi|149363674 hypothetical protein LOC25758 [Homo sapiens]              30   3.9  
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    29   5.0  
gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]    29   5.0  

>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score =  663 bits (1710), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
           MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60

Query: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
           DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120

Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
           TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180

Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
           YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240

Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300
           AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300

Query: 301 YIIEGFENMPAAFMGMLKGDNLGKTIVKA 329
           YIIEGFENMPAAFMGMLKGDNLGKTIVKA
Sbjct: 301 YIIEGFENMPAAFMGMLKGDNLGKTIVKA 329


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score =  663 bits (1710), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
           MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60

Query: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
           DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120

Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
           TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180

Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
           YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240

Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300
           AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300

Query: 301 YIIEGFENMPAAFMGMLKGDNLGKTIVKA 329
           YIIEGFENMPAAFMGMLKGDNLGKTIVKA
Sbjct: 301 YIIEGFENMPAAFMGMLKGDNLGKTIVKA 329


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score =  593 bits (1528), Expect = e-170
 Identities = 295/300 (98%), Positives = 297/300 (99%)

Query: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
           MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1   MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60

Query: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
           DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61  DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120

Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
           TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180

Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
           YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240

Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300
           AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLE K + +E
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE 300


>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  203 bits (516), Expect = 2e-52
 Identities = 134/331 (40%), Positives = 183/331 (55%), Gaps = 21/331 (6%)

Query: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75

Query: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134

Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194

Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253

Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEGKI 296
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  EGK+
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312

Query: 297 QYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
           + KE +I G ENM AAF  M+ G N+GK IV
Sbjct: 313 KIKETVINGLENMGAAFQSMMTGGNIGKQIV 343


>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  203 bits (516), Expect = 2e-52
 Identities = 134/331 (40%), Positives = 183/331 (55%), Gaps = 21/331 (6%)

Query: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75

Query: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134

Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194

Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253

Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEGKI 296
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  EGK+
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312

Query: 297 QYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
           + KE +I G ENM AAF  M+ G N+GK IV
Sbjct: 313 KIKETVINGLENMGAAFQSMMTGGNIGKQIV 343


>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score =  203 bits (516), Expect = 2e-52
 Identities = 134/331 (40%), Positives = 183/331 (55%), Gaps = 21/331 (6%)

Query: 15  GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
           G P   +F ++   LP  +  G+V +  L+L+VDPYMR         D +   Q+++VV 
Sbjct: 16  GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75

Query: 73  --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
                   ESK+  L KG  V +    W T  I DG  LEK+  +  D   LS  LG +G
Sbjct: 76  GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134

Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
           MPGLT+  G+ E   +  G  +T++V+ AAGA GSV GQI    GC +VVG  G+ EK  
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194

Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
            L  +LGFD   NYK  +++ E L+++ P G D YFDNVGG  S+TVI QM +   I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253

Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEGKI 296
           G IS YN+  P PP   P I   Q+ R    E F+V  ++ D  +  +  L +W  EGK+
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312

Query: 297 QYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
           + KE +I G ENM AAF  M+ G N+GK IV
Sbjct: 313 KIKETVINGLENMGAAFQSMMTGGNIGKQIV 343


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score =  100 bits (248), Expect = 2e-21
 Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 13/219 (5%)

Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
           T+ + G TAY  L E+ G+  G+ V+V AAAG  G    Q++K   C V+G   SDEK A
Sbjct: 152 TLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSA 211

Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
           +L+ LG D   NYKT E +   LK+  P+G D  +++VGG   +  +  +   GR+ + G
Sbjct: 212 FLKSLGCDRPINYKT-EPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIG 270

Query: 241 AISTYNR-TG--PLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQ 297
            IS Y   TG  P+  G  P  ++ +   ++ F +  +     Q A+  LL+  + G + 
Sbjct: 271 FISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYL-SKYQAAMSHLLEMCVSGDLV 329

Query: 298 YK--------EYIIEGFENMPAAFMGMLKGDNLGKTIVK 328
            +        E    G E++  A   M  G N GK +V+
Sbjct: 330 CEVDLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVVE 368


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 12/187 (6%)

Query: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125

Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184

Query: 178 KVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIA 237
               + + G   VFN++ V  +++  K     G D   + +     +  +  +   GR+ 
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVI 244

Query: 238 ICGAIST 244
           + G+  T
Sbjct: 245 VVGSRGT 251


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 12/187 (6%)

Query: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125

Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184

Query: 178 KVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIA 237
               + + G   VFN++ V  +++  K     G D   + +     +  +  +   GR+ 
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVI 244

Query: 238 ICGAIST 244
           + G+  T
Sbjct: 245 VVGSRGT 251


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
           E LL   P+ + L+ A   +    LTA F LL + G V+ G+ V+++A    VG+   Q+
Sbjct: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160

Query: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
            ++ G   +   GS +K+   +KLG    FNYK  +  E TLK     G +   D +GG 
Sbjct: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220

Query: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
           +    +  +   GR  + G +   +  GPL
Sbjct: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
           E LL   P+ + L+ A   +    LTA F LL + G V+ G+ V+++A    VG+   Q+
Sbjct: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160

Query: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
            ++ G   +   GS +K+   +KLG    FNYK  +  E TLK     G +   D +GG 
Sbjct: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220

Query: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
           +    +  +   GR  + G +   +  GPL
Sbjct: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 12/144 (8%)

Query: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125

Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184

Query: 178 KVAYLQKLGFDVVFNYKTVESLEE 201
               + + G   VFN++ V  +++
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDK 208


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 71/285 (24%), Positives = 127/285 (44%), Gaps = 34/285 (11%)

Query: 23  ELKTAELPPLKNGEVLLEALFLTVDP----YMRVAAKRLKEGDTMMGQQ-VAKVVE-SKN 76
           ELK  EL  ++  +V ++ L   ++P     ++     L E   + G + VA+VV    N
Sbjct: 59  ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSN 118

Query: 77  VA--LPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYF 131
           V    P   ++ A+ G   W T ++      E+ L + P  IPL  A  T+G+   TAY 
Sbjct: 119 VTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLGVNPCTAYR 173

Query: 132 GLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA----YLQKLGF 187
            L++   ++ G++V+ NA+   VG  V QIA   G + +  V     +      L+ LG 
Sbjct: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGA 233

Query: 188 DVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243
           + V   + +   E +   K  P      +C    VGG+ S  ++ Q+ + G +       
Sbjct: 234 EHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGTMV------ 283

Query: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLL 288
           TY      P      ++I+++L++  F + +W+ D      K+L+
Sbjct: 284 TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELI 328


>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
          Length = 192

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 32/112 (28%), Positives = 56/112 (50%)

Query: 133 LLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFN 192
           LL    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E    + + G   VFN
Sbjct: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62

Query: 193 YKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIST 244
           ++ V  +++  K     G D   + +     +  +  +   GR+ + G+  T
Sbjct: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 114


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 61/213 (28%), Positives = 97/213 (45%), Gaps = 17/213 (7%)

Query: 127 LTAYFGLLEICGVKG----GETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL 182
           LTA+  + ++ G+      G+ V++  A+G VG+   Q+ K     V  AV S +    +
Sbjct: 186 LTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVT-AVCSQDASELV 244

Query: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAI 242
           +KLG D V +YK+  S+EE LK   P  +D   DNVGG         +KK+        +
Sbjct: 245 RKLGADDVIDYKS-GSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLV 301

Query: 243 STY----NRTGPLPPGPPPEIVIYQELRMEAF---VVYRWQGD-ARQKALKDLLKWVLEG 294
           + +    +R G +  G     V      ++ F   V YRW    A    L D+ + V  G
Sbjct: 302 TPFLLNMDRLG-IADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG 360

Query: 295 KIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
           KI+        F  +P AF+ + +G   GKT++
Sbjct: 361 KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 393


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 57/233 (24%), Positives = 102/233 (43%), Gaps = 26/233 (11%)

Query: 67  QVAKVVESKNVALPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
           QV  V  +     P   ++ A+ G   W T ++      E+ L + P  IPL  A  T+G
Sbjct: 35  QVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLG 89

Query: 124 MPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA--- 180
           +   TAY  L++   ++ G++V+ NA+   VG  V QIA   G + +  V     +    
Sbjct: 90  VNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLS 149

Query: 181 -YLQKLGFDVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGR 235
             L+ LG + V   + +   E +   K  P      +C    VGG+ S  ++ Q+ + G 
Sbjct: 150 DRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGT 205

Query: 236 IAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLL 288
           +       TY      P      ++I+++L++  F + +W+ D      K+L+
Sbjct: 206 MV------TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELI 252


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)

Query: 127 LTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLG 186
           +TAY  L +   ++ G +V+V+ AAG VG    Q+ +      V    S  K   L++ G
Sbjct: 174 ITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENG 233

Query: 187 FDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYN 246
                +Y T + ++E +KK SP G D   D +GG  +      +K  G++   G  +   
Sbjct: 234 VTHPIDYHTTDYVDE-IKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLL- 291

Query: 247 RTGP 250
            TGP
Sbjct: 292 -TGP 294


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 49/206 (23%), Positives = 91/206 (44%), Gaps = 9/206 (4%)

Query: 128  TAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ---- 183
            TAY+ L+    V+ GET+++++ +G VG     IA   GC+V   VGS EK AYLQ    
Sbjct: 1654 TAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFP 1713

Query: 184  KLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243
            +L      N +     +  L      G D   +++  E     +  +   GR    G   
Sbjct: 1714 QLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFD 1773

Query: 244  TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLK-WVLEGKIQYKEYI 302
              ++  PL      + V +  + ++AF     +  A  + +  L++  + +G ++  +  
Sbjct: 1774 -LSQNHPLGMAIFLKNVTFHGVLLDAFFN---ESSADWREVWALVQAGIRDGVVRPLKCT 1829

Query: 303  IEGFENMPAAFMGMLKGDNLGKTIVK 328
            +     +  AF  M +G ++GK +V+
Sbjct: 1830 VFHGAQVEDAFRYMAQGKHIGKVVVQ 1855


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)

Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 162
           E  L   P+ +  + A G++   G+ AY  L  +  +  G++V++   A A G++  Q+A
Sbjct: 107 EHYLVHKPEKVTWTEAAGSI-RDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLA 165

Query: 163 KLKGCKVVGAVGSDEKVAYLQK 184
             +G KV+    S E    L++
Sbjct: 166 HHRGAKVISTACSLEDKQCLER 187


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 17/107 (15%)

Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
           +G    T Y   +++  V  G T  V    G   SVV       GCK  GA        +
Sbjct: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226

Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271


>gi|4502119 amine oxidase, copper containing 3 precursor [Homo
           sapiens]
          Length = 763

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
           +L  +G +++ N+K ++    T++K    G   Y+D++    +    G +     I   G
Sbjct: 239 FLHHVGLELLVNHKALDPARWTIQKVFYQGR--YYDSLAQLEAQFEAGLVNVV-LIPDNG 295

Query: 241 AISTYNRTGPLPPGPPPEIVIYQE 264
              +++   P+PPGP P +  Y +
Sbjct: 296 TGGSWSLKSPVPPGPAPPLQFYPQ 319


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226

Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDIN 226

Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271


>gi|149363674 hypothetical protein LOC25758 [Homo sapiens]
          Length = 1855

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 224 NTVIGQMKKFGRIAICGAISTYNRTGPLPPGPP-PEIVIYQ 263
           +TV G +  F   ++   I T  RT PLP GPP P I+  Q
Sbjct: 296 HTVNGFVSDFSTGSVSSPIITAPRTNPLPSGPPLPSILSIQ 336


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 13/25 (52%), Positives = 17/25 (68%)

Query: 110 PDTIPLSLALGTVGMPGLTAYFGLL 134
           P +IPL+LAL   G+P  T YF +L
Sbjct: 781 PGSIPLALALSNSGLPTPTPYFPIL 805


>gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]
          Length = 1166

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 13/25 (52%), Positives = 17/25 (68%)

Query: 110 PDTIPLSLALGTVGMPGLTAYFGLL 134
           P +IPL+LAL   G+P  T YF +L
Sbjct: 781 PGSIPLALALSNSGLPTPTPYFPIL 805


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,894,698
Number of Sequences: 37866
Number of extensions: 570583
Number of successful extensions: 1937
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1891
Number of HSP's gapped (non-prelim): 27
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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