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Search of human proteins with 226056130
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
(301 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 607 e-174
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 593 e-170
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 593 e-170
gi|226246682 prostaglandin reductase 2 [Homo sapiens] 166 2e-41
gi|226246680 prostaglandin reductase 2 [Homo sapiens] 166 2e-41
gi|22748929 prostaglandin reductase 2 [Homo sapiens] 166 2e-41
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 93 3e-19
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 68 9e-12
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 68 9e-12
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 60 2e-09
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 60 2e-09
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 60 2e-09
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 59 4e-09
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 57 3e-08
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 57 3e-08
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 52 5e-07
gi|41872631 fatty acid synthase [Homo sapiens] 48 9e-06
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 47 2e-05
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 35 0.11
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 31 1.5
gi|4502119 amine oxidase, copper containing 3 precursor [Homo sa... 31 1.5
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 30 2.6
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 30 3.4
gi|149363674 hypothetical protein LOC25758 [Homo sapiens] 30 3.4
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 29 4.4
gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens] 29 4.4
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 28 9.9
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 607 bits (1565), Expect = e-174
Identities = 301/301 (100%), Positives = 301/301 (100%)
Query: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
Query: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE 300
AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE 300
Query: 301 D 301
D
Sbjct: 301 D 301
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 593 bits (1528), Expect = e-170
Identities = 295/300 (98%), Positives = 297/300 (99%)
Query: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
Query: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE 300
AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLE K + +E
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 593 bits (1528), Expect = e-170
Identities = 295/300 (98%), Positives = 297/300 (99%)
Query: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG
Sbjct: 1 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG 60
Query: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG
Sbjct: 61 DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG 120
Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA
Sbjct: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG
Sbjct: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
Query: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENEE 300
AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLE K + +E
Sbjct: 241 AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE 300
>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 166 bits (420), Expect = 2e-41
Identities = 117/304 (38%), Positives = 163/304 (53%), Gaps = 21/304 (6%)
Query: 15 GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
G P +F ++ LP + G+V + L+L+VDPYMR D + Q+++VV
Sbjct: 16 GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
Query: 73 --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
ESK+ L KG V + W T I DG LEK+ + D LS LG +G
Sbjct: 76 GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
MPGLT+ G+ E + G +T++V+ AAGA GSV GQI GC +VVG G+ EK
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
L +LGFD NYK +++ E L+++ P G D YFDNVGG S+TVI QM + I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEIKR 296
G IS YN+ P PP P I Q+ R E F+V ++ D + + L +W E K
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
Query: 297 ENEE 300
+ +E
Sbjct: 313 KIKE 316
>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 166 bits (420), Expect = 2e-41
Identities = 117/304 (38%), Positives = 163/304 (53%), Gaps = 21/304 (6%)
Query: 15 GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
G P +F ++ LP + G+V + L+L+VDPYMR D + Q+++VV
Sbjct: 16 GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
Query: 73 --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
ESK+ L KG V + W T I DG LEK+ + D LS LG +G
Sbjct: 76 GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
MPGLT+ G+ E + G +T++V+ AAGA GSV GQI GC +VVG G+ EK
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
L +LGFD NYK +++ E L+++ P G D YFDNVGG S+TVI QM + I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEIKR 296
G IS YN+ P PP P I Q+ R E F+V ++ D + + L +W E K
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
Query: 297 ENEE 300
+ +E
Sbjct: 313 KIKE 316
>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 166 bits (420), Expect = 2e-41
Identities = 117/304 (38%), Positives = 163/304 (53%), Gaps = 21/304 (6%)
Query: 15 GYPTNSDFELKTAELPP-LKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVV- 72
G P +F ++ LP + G+V + L+L+VDPYMR D + Q+++VV
Sbjct: 16 GNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVD 75
Query: 73 --------ESKNVALPKGTIVLASPG-WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
ESK+ L KG V + W T I DG LEK+ + D LS LG +G
Sbjct: 76 GGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDG-HLSYFLGAIG 134
Query: 124 MPGLTAYFGLLEICGVKGG--ETVMVNAAAGAVGSVVGQIAKLKGC-KVVGAVGSDEKVA 180
MPGLT+ G+ E + G +T++V+ AAGA GSV GQI GC +VVG G+ EK
Sbjct: 135 MPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCI 194
Query: 181 YL-QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAIC 239
L +LGFD NYK +++ E L+++ P G D YFDNVGG S+TVI QM + I +C
Sbjct: 195 LLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILC 253
Query: 240 GAISTYNRTGPLPPGPPPEIVIYQELR---MEAFVVYRWQGDARQKALKDLLKWVLEIKR 296
G IS YN+ P PP P I Q+ R E F+V ++ D + + L +W E K
Sbjct: 254 GQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYK-DKFEPGILQLSQWFKEGKL 312
Query: 297 ENEE 300
+ +E
Sbjct: 313 KIKE 316
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 92.8 bits (229), Expect = 3e-19
Identities = 59/172 (34%), Positives = 91/172 (52%), Gaps = 5/172 (2%)
Query: 121 TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA 180
T+ + G TAY L E+ G+ G+ V+V AAAG G Q++K C V+G SDEK A
Sbjct: 152 TLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSA 211
Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
+L+ LG D NYKT E + LK+ P+G D +++VGG + + + GR+ + G
Sbjct: 212 FLKSLGCDRPINYKT-EPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIG 270
Query: 241 AISTYNR-TG--PLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLK 289
IS Y TG P+ G P ++ + ++ F + + Q A+ LL+
Sbjct: 271 FISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYL-SKYQAAMSHLLE 321
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 68.2 bits (165), Expect = 9e-12
Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 12/187 (6%)
Query: 65 GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
G VA V+E+ A KG V S G+ ++++ + KL P+ +
Sbjct: 70 GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
+G+P TAY L+ VK GE+V+V+ A+G VG QIA+ G K++G G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
Query: 178 KVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIA 237
+ + G VFN++ V +++ K G D + + + + + GR+
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVI 244
Query: 238 ICGAIST 244
+ G+ T
Sbjct: 245 VVGSRGT 251
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 68.2 bits (165), Expect = 9e-12
Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 12/187 (6%)
Query: 65 GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
G VA V+E+ A KG V S G+ ++++ + KL P+ +
Sbjct: 70 GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
+G+P TAY L+ VK GE+V+V+ A+G VG QIA+ G K++G G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
Query: 178 KVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIA 237
+ + G VFN++ V +++ K G D + + + + + GR+
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVI 244
Query: 238 ICGAIST 244
+ G+ T
Sbjct: 245 VVGSRGT 251
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+
Sbjct: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
Query: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
++ G + GS +K+ +KLG FNYK + E TLK G + D +GG
Sbjct: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
Query: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
+ + + GR + G + + GPL
Sbjct: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+
Sbjct: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
Query: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
++ G + GS +K+ +KLG FNYK + E TLK G + D +GG
Sbjct: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
Query: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
+ + + GR + G + + GPL
Sbjct: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 60.5 bits (145), Expect = 2e-09
Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 12/144 (8%)
Query: 65 GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117
G VA V+E+ A KG V S G+ ++++ + KL P+ +
Sbjct: 70 GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
Query: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177
+G+P TAY L+ VK GE+V+V+ A+G VG QIA+ G K++G G++E
Sbjct: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
Query: 178 KVAYLQKLGFDVVFNYKTVESLEE 201
+ + G VFN++ V +++
Sbjct: 185 GQKIVLQNGAHEVFNHREVNYIDK 208
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 59.3 bits (142), Expect = 4e-09
Identities = 72/296 (24%), Positives = 132/296 (44%), Gaps = 34/296 (11%)
Query: 23 ELKTAELPPLKNGEVLLEALFLTVDP----YMRVAAKRLKEGDTMMGQQ-VAKVVE-SKN 76
ELK EL ++ +V ++ L ++P ++ L E + G + VA+VV N
Sbjct: 59 ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSN 118
Query: 77 VA--LPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYF 131
V P ++ A+ G W T ++ E+ L + P IPL A T+G+ TAY
Sbjct: 119 VTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLGVNPCTAYR 173
Query: 132 GLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA----YLQKLGF 187
L++ ++ G++V+ NA+ VG V QIA G + + V + L+ LG
Sbjct: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGA 233
Query: 188 DVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243
+ V + + E + K P +C VGG+ S ++ Q+ + G +
Sbjct: 234 EHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGTMV------ 283
Query: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIKRENE 299
TY P ++I+++L++ F + +W+ D K+L+ + ++ R +
Sbjct: 284 TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQ 339
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/244 (23%), Positives = 107/244 (43%), Gaps = 26/244 (10%)
Query: 67 QVAKVVESKNVALPKGTIVLASPG---WTTHSISDGKDLEKLLTEWPDTIPLSLALGTVG 123
QV V + P ++ A+ G W T ++ E+ L + P IPL A T+G
Sbjct: 35 QVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS----EEALIQVPSDIPLQSA-ATLG 89
Query: 124 MPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA--- 180
+ TAY L++ ++ G++V+ NA+ VG V QIA G + + V +
Sbjct: 90 VNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLS 149
Query: 181 -YLQKLGFDVVFNYKTVESLE-ETLKKASPD---GYDCYFDNVGGEFSNTVIGQMKKFGR 235
L+ LG + V + + E + K P +C VGG+ S ++ Q+ + G
Sbjct: 150 DRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNC----VGGKSSTELLRQLARGGT 205
Query: 236 IAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEIK 295
+ TY P ++I+++L++ F + +W+ D K+L+ + ++
Sbjct: 206 MV------TYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLI 259
Query: 296 RENE 299
R +
Sbjct: 260 RRGQ 263
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 56.6 bits (135), Expect = 3e-08
Identities = 32/112 (28%), Positives = 56/112 (50%)
Query: 133 LLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFN 192
LL VK GE+V+V+ A+G VG QIA+ G K++G G++E + + G VFN
Sbjct: 3 LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
Query: 193 YKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIST 244
++ V +++ K G D + + + + + GR+ + G+ T
Sbjct: 63 HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 114
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 52.4 bits (124), Expect = 5e-07
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 127 LTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLG 186
+TAY L + ++ G +V+V+ AAG VG Q+ + V S K L++ G
Sbjct: 174 ITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENG 233
Query: 187 FDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYN 246
+Y T + ++E +KK SP G D D +GG + +K G++ G +
Sbjct: 234 VTHPIDYHTTDYVDE-IKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLL- 291
Query: 247 RTGP 250
TGP
Sbjct: 292 -TGP 294
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 48.1 bits (113), Expect = 9e-06
Identities = 25/56 (44%), Positives = 35/56 (62%)
Query: 128 TAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ 183
TAY+ L+ V+ GET+++++ +G VG IA GC+V VGS EK AYLQ
Sbjct: 1654 TAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQ 1709
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 8/111 (7%)
Query: 127 LTAYFGLLEICGVKG----GETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL 182
LTA+ + ++ G+ G+ V++ A+G VG+ Q+ K V AV S + +
Sbjct: 186 LTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVT-AVCSQDASELV 244
Query: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKF 233
+KLG D V +YK+ S+EE LK P +D DNVGG +KK+
Sbjct: 245 RKLGADDVIDYKS-GSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKW 292
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 34.7 bits (78), Expect = 0.11
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 162
E L P+ + + A G++ G+ AY L + + G++V++ A A G++ Q+A
Sbjct: 107 EHYLVHKPEKVTWTEAAGSI-RDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLA 165
Query: 163 KLKGCKVVGAVGSDEKVAYLQK 184
+G KV+ S E L++
Sbjct: 166 HHRGAKVISTACSLEDKQCLER 187
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 30.8 bits (68), Expect = 1.5
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 17/107 (15%)
Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
+G T Y +++ V G T V G SVV GCK GA +
Sbjct: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226
Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
+K A ++LG N YK + ++E LK+ + G D F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
>gi|4502119 amine oxidase, copper containing 3 precursor [Homo
sapiens]
Length = 763
Score = 30.8 bits (68), Expect = 1.5
Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 181 YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG 240
+L +G +++ N+K ++ T++K G Y+D++ + G + I G
Sbjct: 239 FLHHVGLELLVNHKALDPARWTIQKVFYQGR--YYDSLAQLEAQFEAGLVNVV-LIPDNG 295
Query: 241 AISTYNRTGPLPPGPPPEIVIYQE 264
+++ P+PPGP P + Y +
Sbjct: 296 TGGSWSLKSPVPPGPAPPLQFYPQ 319
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 30.0 bits (66), Expect = 2.6
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)
Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
+G T Y + + V G T V G VG ++ + GCK GA +
Sbjct: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226
Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
+K A ++LG N YK + ++E LK+ + G D F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 29.6 bits (65), Expect = 3.4
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)
Query: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175
+G T Y + + V G T V G VG ++ + GCK GA +
Sbjct: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDIN 226
Query: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219
+K A ++LG N YK + ++E LK+ + G D F+ +G
Sbjct: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
>gi|149363674 hypothetical protein LOC25758 [Homo sapiens]
Length = 1855
Score = 29.6 bits (65), Expect = 3.4
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 224 NTVIGQMKKFGRIAICGAISTYNRTGPLPPGPP-PEIVIYQ 263
+TV G + F ++ I T RT PLP GPP P I+ Q
Sbjct: 296 HTVNGFVSDFSTGSVSSPIITAPRTNPLPSGPPLPSILSIQ 336
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/25 (52%), Positives = 17/25 (68%)
Query: 110 PDTIPLSLALGTVGMPGLTAYFGLL 134
P +IPL+LAL G+P T YF +L
Sbjct: 781 PGSIPLALALSNSGLPTPTPYFPIL 805
>gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]
Length = 1166
Score = 29.3 bits (64), Expect = 4.4
Identities = 13/25 (52%), Positives = 17/25 (68%)
Query: 110 PDTIPLSLALGTVGMPGLTAYFGLL 134
P +IPL+LAL G+P T YF +L
Sbjct: 781 PGSIPLALALSNSGLPTPTPYFPIL 805
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 28.1 bits (61), Expect = 9.9
Identities = 10/14 (71%), Positives = 11/14 (78%)
Query: 249 GPLPPGPPPEIVIY 262
GPLPPGPPP + Y
Sbjct: 290 GPLPPGPPPPVPGY 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,024,671
Number of Sequences: 37866
Number of extensions: 530373
Number of successful extensions: 1844
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1799
Number of HSP's gapped (non-prelim): 30
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.