Guide to the Human Genome
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Search of human proteins with 225637463

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225637463 transketolase-like 1 isoform c [Homo sapiens]           1082   0.0  
gi|225637461 transketolase-like 1 isoform b [Homo sapiens]           1082   0.0  
gi|225637459 transketolase-like 1 isoform a [Homo sapiens]           1082   0.0  
gi|133778974 transketolase-like 2 [Homo sapiens]                      837   0.0  
gi|205277463 transketolase isoform 1 [Homo sapiens]                   686   0.0  
gi|4507521 transketolase isoform 1 [Homo sapiens]                     686   0.0  
gi|205277465 transketolase isoform 2 [Homo sapiens]                   627   e-180
gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]    60   4e-09
gi|4557353 branched chain keto acid dehydrogenase E1 beta precur...    43   8e-04
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu...    43   8e-04
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    32   1.9  
gi|33624873 spectrin repeat containing, nuclear envelope 2 isofo...    32   1.9  
gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo s...    30   5.6  
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    30   7.3  
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     30   7.3  
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     30   7.3  
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    30   7.3  
gi|30578420 organic solute transporter beta [Homo sapiens]             29   9.6  
gi|166235167 zinc finger protein ZNF-U69274 [Homo sapiens]             29   9.6  

>gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
          Length = 540

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 60
           MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA
Sbjct: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 60

Query: 61  SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 120
           SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR
Sbjct: 61  SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 120

Query: 121 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 180
           CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM
Sbjct: 121 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 180

Query: 181 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 240
           PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG
Sbjct: 181 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 240

Query: 241 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 300
           LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT
Sbjct: 241 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 300

Query: 301 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 360
           IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK
Sbjct: 301 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 360

Query: 361 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 420
           CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK
Sbjct: 361 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 420

Query: 421 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 480
           VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH
Sbjct: 421 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 480

Query: 481 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 540
           YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 481 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 540


>gi|225637461 transketolase-like 1 isoform b [Homo sapiens]
          Length = 590

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 60
           MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA
Sbjct: 51  MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 110

Query: 61  SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 120
           SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR
Sbjct: 111 SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 170

Query: 121 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 180
           CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM
Sbjct: 171 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 230

Query: 181 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 240
           PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG
Sbjct: 231 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 290

Query: 241 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 300
           LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT
Sbjct: 291 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 350

Query: 301 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 360
           IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK
Sbjct: 351 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 410

Query: 361 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 420
           CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK
Sbjct: 411 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 470

Query: 421 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 480
           VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH
Sbjct: 471 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 530

Query: 481 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 540
           YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 531 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 590


>gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
          Length = 596

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 60
           MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA
Sbjct: 57  MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 116

Query: 61  SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 120
           SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR
Sbjct: 117 SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 176

Query: 121 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 180
           CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM
Sbjct: 177 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 236

Query: 181 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 240
           PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG
Sbjct: 237 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 296

Query: 241 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 300
           LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT
Sbjct: 297 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 356

Query: 301 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 360
           IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK
Sbjct: 357 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 416

Query: 361 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 420
           CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK
Sbjct: 417 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 476

Query: 421 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 480
           VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH
Sbjct: 477 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 536

Query: 481 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 540
           YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 537 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 596


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score =  837 bits (2161), Expect = 0.0
 Identities = 411/577 (71%), Positives = 476/577 (82%), Gaps = 38/577 (6%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAK-------------------------------- 28
           +SVLFF+ M+YKQ+DPE+PDNDRF+L++                                
Sbjct: 49  VSVLFFHTMKYKQTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDL 108

Query: 29  ------RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAM 82
                 RL FVDVATG LGQGLG ACGMAYTGKY D+ASYRVFCLM DGESSEGSVWEA 
Sbjct: 109 ERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAF 168

Query: 83  AFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQV 142
           AFAS+Y+LDNLVA+FDVNRLG SG  P EH  +IYQ  CEAFGWNTY+VDG DVEALCQ 
Sbjct: 169 AFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQA 228

Query: 143 FWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNL 202
           FWQASQVK+KPTA+VAKTFKGRG P+IEDAE+WH KP+P+ERADAI+KLIESQIQT+ NL
Sbjct: 229 FWQASQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENL 288

Query: 203 DPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRY 262
            P+ P+EDSP+++ITD++MTSPP Y+VGDKIAT+K  GLALAKLG AN RV+VL GDT  
Sbjct: 289 IPKSPVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMN 348

Query: 263 STFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGG 322
           STFSEIF KE+PERFIEC +AEQNMVSVALGCA+RGRTIAFA  FAAF TRAFD +R+G 
Sbjct: 349 STFSEIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGA 408

Query: 323 LAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANA 382
           ++++NIN+IGSHCGVS G+DG SQMALED+AMFR+IP CT+FYP+DA+STEHA+ LAAN 
Sbjct: 409 ISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANT 468

Query: 383 KGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSK 442
           KGMCFIRT++PET VIYTPQE FEIGQAKV+RH V+DKVTVIGAG+T++EAL AAD LS+
Sbjct: 469 KGMCFIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQ 528

Query: 443 QDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQV 502
           Q I +RVID FTIKPLD ATI+SSAKAT GR+ITVEDHY +GGIGEAVCAAVS +PDI V
Sbjct: 529 QGISVRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILV 588

Query: 503 HSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLL 539
           H LAVSGVPQ GK+ ELLDM+GIS RHII AV   L+
Sbjct: 589 HQLAVSGVPQRGKTSELLDMFGISTRHIIAAVTLTLM 625


>gi|205277463 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  686 bits (1771), Expect = 0.0
 Identities = 344/576 (59%), Positives = 428/576 (74%), Gaps = 41/576 (7%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAK-------------------------------- 28
           M+VLFF+ MRYK  DP NP NDRFVL+K                                
Sbjct: 48  MAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDL 107

Query: 29  ------RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAM 82
                 + +F DVATG LGQGLG ACGMAYTGKYFD+ASYRV+CL+ DGE SEGSVWEAM
Sbjct: 108 DGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAM 167

Query: 83  AFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQV 142
           AFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE LC+ 
Sbjct: 168 AFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKA 227

Query: 143 FWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNL 202
           F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ + +
Sbjct: 228 FGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKI 284

Query: 203 DPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRY 262
              PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGDT+ 
Sbjct: 285 LATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKN 344

Query: 263 STFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGG 322
           STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR+  
Sbjct: 345 STFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAA 404

Query: 323 LAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANA 382
           ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV LAAN 
Sbjct: 405 ISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANT 464

Query: 383 KGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSK 442
           KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+ L K
Sbjct: 465 KGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKK 524

Query: 443 QDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQV 502
           + I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P I V
Sbjct: 525 EKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITV 584

Query: 503 HSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 538
             LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 585 THLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 620


>gi|4507521 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  686 bits (1771), Expect = 0.0
 Identities = 344/576 (59%), Positives = 428/576 (74%), Gaps = 41/576 (7%)

Query: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAK-------------------------------- 28
           M+VLFF+ MRYK  DP NP NDRFVL+K                                
Sbjct: 48  MAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDL 107

Query: 29  ------RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAM 82
                 + +F DVATG LGQGLG ACGMAYTGKYFD+ASYRV+CL+ DGE SEGSVWEAM
Sbjct: 108 DGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAM 167

Query: 83  AFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQV 142
           AFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE LC+ 
Sbjct: 168 AFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKA 227

Query: 143 FWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNL 202
           F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ + +
Sbjct: 228 FGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKI 284

Query: 203 DPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRY 262
              PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGDT+ 
Sbjct: 285 LATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKN 344

Query: 263 STFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGG 322
           STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR+  
Sbjct: 345 STFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAA 404

Query: 323 LAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANA 382
           ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV LAAN 
Sbjct: 405 ISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANT 464

Query: 383 KGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSK 442
           KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+ L K
Sbjct: 465 KGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKK 524

Query: 443 QDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQV 502
           + I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P I V
Sbjct: 525 EKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITV 584

Query: 503 HSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 538
             LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 585 THLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 620


>gi|205277465 transketolase isoform 2 [Homo sapiens]
          Length = 540

 Score =  627 bits (1617), Expect = e-180
 Identities = 313/519 (60%), Positives = 396/519 (76%), Gaps = 13/519 (2%)

Query: 29  RLSFVDVATGWLGQGLGVACGMA---------YTGKYFDRASYRVFCLMSDGESSEGSVW 79
           R+S +   T   G G   +C  A         +TGKYFD+ASYRV+CL+ DGE SEGSVW
Sbjct: 23  RISSIQATTA-AGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVW 81

Query: 80  EAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEAL 139
           EAMAFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE L
Sbjct: 82  EAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEEL 141

Query: 140 CQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTS 199
           C+ F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ 
Sbjct: 142 CKAFGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSK 198

Query: 200 RNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGD 259
           + +   PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGD
Sbjct: 199 KKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGD 258

Query: 260 TRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIR 319
           T+ STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR
Sbjct: 259 TKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIR 318

Query: 320 IGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALA 379
           +  ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV LA
Sbjct: 319 MAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELA 378

Query: 380 ANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADE 439
           AN KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+ 
Sbjct: 379 ANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEL 438

Query: 440 LSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPD 499
           L K+ I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P 
Sbjct: 439 LKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPG 498

Query: 500 IQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 538
           I V  LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 499 ITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 537


>gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]
          Length = 359

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 82/306 (26%), Positives = 129/306 (42%), Gaps = 44/306 (14%)

Query: 259 DTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRG-RTIAFASTFAAFLTRAFDH 317
           D  Y     ++ K   +R I+  ++E     +A+G A  G R I    TF  F  +A D 
Sbjct: 64  DGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFN-FSMQAIDQ 122

Query: 318 I---------RIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTD 368
           +           GGL    I   G + G S G   A+Q +    A +   P   +  P +
Sbjct: 123 VINSAAKTYYMSGGLQPVPIVFRGPN-GASAGV--AAQHSQCFAAWYGHCPGLKVVSPWN 179

Query: 369 AVSTEHAVALAANAKGMCFIRTTRP----ETMVIYTPQERFE-----------IGQAKVL 413
           +   E A  L  +A     IR   P    E  ++Y     F            IG+AK+ 
Sbjct: 180 S---EDAKGLIKSA-----IRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIE 231

Query: 414 RHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGR 473
           R      +TV+     V   L AA  LSK+ +   VI++ TI+P+D+ TI +S   T   
Sbjct: 232 RQ--GTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKT-NH 288

Query: 474 IITVEDHYPQGGIGEAVCAAVSMDPD---IQVHSLAVSGVPQSGKSEELLDMYGI-SARH 529
           ++TVE  +PQ G+G  +CA +   P    +   ++ V+G        ++L+   I   + 
Sbjct: 289 LVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKD 348

Query: 530 IIVAVK 535
           II A+K
Sbjct: 349 IIFAIK 354


>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
           [Homo sapiens]
          Length = 392

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 275 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 325
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176

Query: 326 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 385
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234

Query: 386 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 434
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288

Query: 435 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 494
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345


>gi|34101272 branched chain keto acid dehydrogenase E1 beta
           precursor [Homo sapiens]
          Length = 392

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 275 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 325
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176

Query: 326 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 385
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234

Query: 386 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 434
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288

Query: 435 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 494
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 156  VVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSP 212
            +  KT K     SI D  SWH    P     +  +    Q++  RN+ P PP   +P
Sbjct: 6458 MTTKTLKASSGKSISDGHSWHVPDSP-----SCPEHHYKQMEGDRNVPPVPPASSTP 6509


>gi|33624873 spectrin repeat containing, nuclear envelope 2 isoform
           4 [Homo sapiens]
          Length = 556

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 156 VVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSP 212
           +  KT K     SI D  SWH    P     +  +    Q++  RN+ P PP   +P
Sbjct: 92  MTTKTLKASSGKSISDGHSWHVPDSP-----SCPEHHYKQMEGDRNVPPVPPASSTP 143


>gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo
           sapiens]
          Length = 1079

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 400 TPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLD 459
           +P+E   I     +R   + KVTV+G G+   +A    D L+ Q+        F +  +D
Sbjct: 106 SPEEINVIQNKTDVRRMSTSKVTVLGYGLLTADAKTLIDALNNQN--------FKVVIVD 157

Query: 460 VATIVSSAKATEGRII 475
            +  + S  AT  RI+
Sbjct: 158 ESHYMKSRNATRSRIL 173


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 165  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 211
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 165  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 211
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 165  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 211
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 165  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 211
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 995  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1041


>gi|30578420 organic solute transporter beta [Homo sapiens]
          Length = 128

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 169 IEDAESWHAKPMPRERADAIIK--LIESQIQTSRNLDPQPPIEDSPEV 214
           +EDA  W+   +       II   L+   IQ SR    QPP +++PEV
Sbjct: 30  VEDASPWNHSILALAAVVVIISMVLLGRSIQASRKETMQPPEKETPEV 77


>gi|166235167 zinc finger protein ZNF-U69274 [Homo sapiens]
          Length = 1053

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 16/63 (25%), Positives = 31/63 (49%)

Query: 183 ERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLA 242
           E  D I K  +++++TS N +        P+++  +V  +SP D  +G+ I+    C   
Sbjct: 410 ESVDLITKNNQTELETSNNRENNTVSNIHPKLSKENVISSSPEDSGMGNDISAEDICAED 469

Query: 243 LAK 245
           + K
Sbjct: 470 IPK 472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,203,090
Number of Sequences: 37866
Number of extensions: 815138
Number of successful extensions: 1651
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1629
Number of HSP's gapped (non-prelim): 23
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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