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Search of human proteins with 225543525
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
(691 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225543525 solute carrier organic anion transporter family, me... 1390 0.0
gi|9790233 solute carrier organic anion transporter family, memb... 1127 0.0
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 966 0.0
gi|8394291 solute carrier organic anion transporter family, memb... 621 e-178
gi|225543118 solute carrier organic anion transporter family, me... 600 e-171
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 542 e-154
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 542 e-154
gi|225543116 solute carrier organic anion transporter family, me... 540 e-153
gi|225543114 solute carrier organic anion transporter family, me... 491 e-138
gi|222831575 solute carrier organic anion transporter family, me... 385 e-107
gi|222831573 solute carrier organic anion transporter family, me... 385 e-107
gi|188528663 solute carrier organic anion transporter family, me... 353 2e-97
gi|38679890 solute carrier organic anion transporter family, mem... 341 1e-93
gi|223634012 solute carrier organic anion transporter family, me... 331 1e-90
gi|6005820 solute carrier organic anion transporter family, memb... 331 1e-90
gi|225637473 solute carrier organic anion transporter family, me... 330 4e-90
gi|39777594 solute carrier organic anion transporter family memb... 287 3e-77
gi|225637475 solute carrier organic anion transporter family, me... 286 4e-77
gi|225637477 solute carrier organic anion transporter family, me... 259 4e-69
gi|223634014 solute carrier organic anion transporter family, me... 258 1e-68
gi|93277099 solute carrier organic anion transporter family, mem... 229 5e-60
gi|11863156 RECK protein precursor [Homo sapiens] 38 0.027
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 38 0.036
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 36 0.14
gi|66082554 low density lipoprotein receptor-related protein 8 i... 35 0.18
gi|54873613 agrin [Homo sapiens] 33 0.68
gi|13236549 major facilitator superfamily domain containing 11 [... 33 0.88
gi|223717983 solute carrier family 37 (glycerol-3-phosphate tran... 33 1.2
gi|38093649 solute carrier family 37 (glycerol-3-phosphate trans... 33 1.2
gi|73747917 transporter 2, ATP-binding cassette, sub-family B is... 33 1.2
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 1390 bits (3598), Expect = 0.0
Identities = 691/691 (100%), Positives = 691/691 (100%)
Query: 1 MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE 60
MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE
Sbjct: 1 MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE 60
Query: 61 ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY 120
ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY
Sbjct: 61 ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY 120
Query: 121 YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML 180
YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML
Sbjct: 121 YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML 180
Query: 181 RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV 240
RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV
Sbjct: 181 RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV 240
Query: 241 DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE 300
DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE
Sbjct: 241 DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE 300
Query: 301 TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF 360
TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF
Sbjct: 301 TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF 360
Query: 361 KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS 420
KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS
Sbjct: 361 KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS 420
Query: 421 FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT 480
FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT
Sbjct: 421 FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT 480
Query: 481 YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI 540
YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI
Sbjct: 481 YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI 540
Query: 541 QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI 600
QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI
Sbjct: 541 QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI 600
Query: 601 KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE 660
KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE
Sbjct: 601 KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE 660
Query: 661 NGSVMDEANLESLNKNKHFVPSAGADSETHC 691
NGSVMDEANLESLNKNKHFVPSAGADSETHC
Sbjct: 661 NGSVMDEANLESLNKNKHFVPSAGADSETHC 691
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 1127 bits (2916), Expect = 0.0
Identities = 551/690 (79%), Positives = 611/690 (88%), Gaps = 1/690 (0%)
Query: 1 MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE 60
MDQ+QHLNKTAE+ SE KKTR CNG KMFLAALS S+IAK LG IIMK SI IERRF+
Sbjct: 1 MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD 60
Query: 61 ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY 120
ISSSL G IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGC +MG G +LT+LPHFFMGY
Sbjct: 61 ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY 120
Query: 121 YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML 180
YRYSKET+IN SENSTS+LSTCLINQ LS N SPEIV K C+KESGS+MWIYVFMGNML
Sbjct: 121 YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML 180
Query: 181 RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV 240
RGIGETPIVPLG+SYIDDFAKEGHSSLYLG LNAI MIGP+IGF LGSLF+KMYVDIGYV
Sbjct: 181 RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV 240
Query: 241 DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE 300
DLSTIRITP DSRWVGAWWL FLVSGLFSIISSIPFFFLP+ PNKPQKERK SLSLHVL+
Sbjct: 241 DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK 300
Query: 301 TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF 360
TND+++QTANLTNQGKN+TKNVTGFFQS KSILTNPLYV+F+LLTLLQVSS+IG+FTYVF
Sbjct: 301 TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF 360
Query: 361 KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS 420
KY+EQQYGQ +S AN LLG+ITIP A+GMFLGG+IIKKFKL+ VGIAKFS T+++S
Sbjct: 361 KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL 420
Query: 421 FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT 480
F LLYF ++CE+KSVAGLT+TYDGNN V SH DVPLSYCNS+CNCDESQWEPVCGNNGIT
Sbjct: 421 FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT 480
Query: 481 YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI 540
Y+SPCLAGCKSSSG KK VFYNCSC+EVTGLQNRNYSAHLGECPRD+ CTRKF+ +VAI
Sbjct: 481 YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI 540
Query: 541 QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI 600
QV+N FSA GGT+ ++L VKIVQPELK+LA+GF SMVIR LGGILAPIYFGALID TC+
Sbjct: 541 QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM 600
Query: 601 KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE 660
KWSTN+CG +G+CR YNS F RVYLGLS LR +LVLYI+ I+AMKKK+Q KD AS+
Sbjct: 601 KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD 660
Query: 661 N-GSVMDEANLESLNKNKHFVPSAGADSET 689
N VMDEANLE LN +HFVPSAG DS+T
Sbjct: 661 NERKVMDEANLEFLNNGEHFVPSAGTDSKT 690
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 966 bits (2497), Expect = 0.0
Identities = 468/637 (73%), Positives = 534/637 (83%), Gaps = 1/637 (0%)
Query: 48 MKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIG 107
MK S IERRFEISSSLVG IDGSFEIGNL VIVFVSYFGSKLHRPKLIGIGCF+MG G
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 108 GVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESG 167
+L ALPHFFMGYYRYSKETNI+ SENSTS L CLINQ+LSLNR EI+ +GC+KESG
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
Query: 168 SYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLG 227
S+MWIYVFMGNMLRGIGETPIVPLG+SYIDDFAKEGHSSLYLG +N + M G + F LG
Sbjct: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
Query: 228 SLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQ 287
SLF+KMYVDIGYVDLSTIRITP DSRWVGAWWL FLVSG+ SIISSIPFFFLP PNKPQ
Sbjct: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
Query: 288 KERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLL 347
KERK SL LHVL+TND+++Q ANLTN+ K ITKNVTGFFQS KSILTNPLYV+FV+ TLL
Sbjct: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
Query: 348 QVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGI 407
+SSYI + TY+ K VEQQYG +SK N LLGV+ +P A GMF GGYIIKKFKL+ VG+
Sbjct: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
Query: 408 AKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDE 467
AK + +A + L +LYFF++CE+KSVAGLT+TYDGN+PV SH DVPLSYCNS+CNCDE
Sbjct: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
Query: 468 SQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRD 527
SQWEPVCGNNGITY+SPCLAGCKSSSGNK+PIVFYNCSC+EV GLQN+NYSAHLGECPRD
Sbjct: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
Query: 528 DACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILA 587
DACTRK Y + IQVL+ F A+G TS+ +L+++IVQPELK+LA+GFHSM++R+LGGIL
Sbjct: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
Query: 588 PIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAM 647
PIYFGALIDTTC+KWSTN+CG RG+CR YNST R + GL L LVL + I+ +
Sbjct: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
Query: 648 KKKYQEKDINASEN-GSVMDEANLESLNKNKHFVPSA 683
+KK KD EN VMDEANLE LN ++HFVPSA
Sbjct: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSA 637
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 621 bits (1602), Expect = e-178
Identities = 300/646 (46%), Positives = 433/646 (67%), Gaps = 10/646 (1%)
Query: 15 PSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFE 74
PS +K C LK+FL ALS + AK L +KS+I IERRF+I SSLVG IDGSFE
Sbjct: 30 PSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFE 89
Query: 75 IGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSEN 134
IGNLLVI FVSYFG+KLHRPK+IG GC IMG+G +L A+P FFM Y+Y + + S N
Sbjct: 90 IGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER---YSPSSN 146
Query: 135 STSTLSTCLINQI----LSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVP 190
ST ++S CL+ +S+ S + C ++ S MWIYVF+GN+LRGIGETPI P
Sbjct: 147 STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQP 206
Query: 191 LGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPT 250
LG++Y+DDFA E +++ Y+G + +A+IGPI GF LGSL +K+YVDIG+V+L I ITP
Sbjct: 207 LGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPK 266
Query: 251 DSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTAN 310
D +WVGAWWL +L++G+ S+++++PF++LP++ + Q ++ S + + D T
Sbjct: 267 DPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHTDY 325
Query: 311 LTNQGKN--ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYG 368
T QG+N I + F S K++ NP+Y +++ + +Q +S G TY KY+EQQYG
Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385
Query: 369 QPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFI 428
Q SS+AN ++G+I IP A G+F GG ++KKF+++ G AK ++V +L F +
Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445
Query: 429 LCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAG 488
CEN VAGLT++Y G PV+ H S CNS C C E++WEP+CG NGITY+S CLAG
Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505
Query: 489 CKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFS 548
C++S+ + K I+FYNC+C+ + ++ N S +G C +D+ C + F +F+ I V+ +
Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565
Query: 549 ALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCG 608
+LGG +L+++ ++P+LKS ALG +++ IR L GI AP+YFG LIDT+C+KW CG
Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625
Query: 609 TRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEK 654
+RGSCR Y+S F +YLGL+ +L S++L I +++ +KK Y K
Sbjct: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 671
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 600 bits (1548), Expect = e-171
Identities = 304/684 (44%), Positives = 432/684 (63%), Gaps = 39/684 (5%)
Query: 15 PSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFE 74
PS +K C LK+FL ALS + AK L +KS+I IERRF+I SSLVG IDGSFE
Sbjct: 30 PSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFE 89
Query: 75 IGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSEN 134
IGNLLVI FVSYFG+KLHRPK+IG GC IMG+G +L A+P FFM Y+Y + + S N
Sbjct: 90 IGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER---YSPSSN 146
Query: 135 STSTLSTCLINQI----LSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVP 190
ST ++S CL+ +S+ S + C ++ S MWIYVF+GN+LRGIGETPI P
Sbjct: 147 STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQP 206
Query: 191 LGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPT 250
LG++Y+DDFA E +++ Y+G + +A+IGPI GF LGSL +K+YVDIG+V+L I ITP
Sbjct: 207 LGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPK 266
Query: 251 DSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTAN 310
D +WVGAWWL +L++G+ S+++++PF++LP++ + Q ++ S + + D T
Sbjct: 267 DPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHTDY 325
Query: 311 LTNQGKN--ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYG 368
T QG+N I + F S K++ NP+Y +++ + +Q +S G TY KY+EQQYG
Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385
Query: 369 QPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFI 428
Q SS+AN ++G+I IP A G+F GG ++KKF+++ G AK ++V +L F +
Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445
Query: 429 LCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAG 488
CEN VAGLT++Y G PV+ H S CNS C C E++WEP+CG NGITY+S CLAG
Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505
Query: 489 CKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFS 548
C++S+ + K I+FYNC+C+ + ++ N S +G C +D+ C + F +F+ I V+ +
Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565
Query: 549 ALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCG 608
+LGG +L+++ ++P+LKS ALG +++ IR L GI AP+YFG LIDT+C+KW CG
Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625
Query: 609 TRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEA 668
+RGSCR Y+S F +YQ K I AS S+ D
Sbjct: 626 SRGSCRLYDSNVF----------------------------RYQIKSIPASHCYSIPDLH 657
Query: 669 NLESLNK-NKHFVPSAGADSETHC 691
N NK + HF S T+C
Sbjct: 658 NATDTNKFSCHFTACKTYISGTNC 681
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 542 bits (1397), Expect = e-154
Identities = 272/635 (42%), Positives = 401/635 (63%), Gaps = 20/635 (3%)
Query: 17 ENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIG 76
E + R + LKMFL A++ +F++KTL M S + IER+F I +SLVGFI+GSFEIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 77 NLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENST 136
NLL+I+FVSYFG+KLHRP +IGIGC +MG+G L +LPHF M Y Y E+ ++ S N +
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
Query: 137 STLSTCLIN--QILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194
S C+ N QIL + E C KE S MW+YV +GN++RG+GETPI+PLG+S
Sbjct: 127 SNSFLCMENGTQILRPTQDPSE-----CTKEVKSLMWVYVLVGNIVRGMGETPILPLGIS 181
Query: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254
YI+DFAK +S LY+G++ A+IGP+IG L S + +YVD G+V+ + ITPTD+RW
Sbjct: 182 YIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRW 241
Query: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314
VGAWW FL+ +++++IPFFFLP T K E A +++ +E Q + +
Sbjct: 242 VGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD----IIKNENEDKQKEEVKKE 297
Query: 315 GKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKA 374
ITK+ F KS+ NP+Y++F+L++++Q ++++ +++ KY+EQQYG SS A
Sbjct: 298 KYGITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
Query: 375 NILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKS 434
L+G+ +P G +GG I+KKFK+ A C+ +++ Y L F + CEN S
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 435 VAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG 494
V G+ +Y+G + + CN DCNC W+PVCGNNG++Y+S CLAGC++S G
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
Query: 495 NKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTS 554
+VF NCSC++ +G N SA LG C + C+ +F+ + ++ F +L
Sbjct: 475 TGINMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
Query: 555 HVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCR 614
M++++ ++ E KSL +G H+ R GI APIYFGAL+D+TC+ W T CG G+CR
Sbjct: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
Query: 615 TYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKK 649
Y+ST+F +YLGL + LR SS V +I++ ++K
Sbjct: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 542 bits (1397), Expect = e-154
Identities = 272/635 (42%), Positives = 401/635 (63%), Gaps = 20/635 (3%)
Query: 17 ENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIG 76
E + R + LKMFL A++ +F++KTL M S + IER+F I +SLVGFI+GSFEIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 77 NLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENST 136
NLL+I+FVSYFG+KLHRP +IGIGC +MG+G L +LPHF M Y Y E+ ++ S N +
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
Query: 137 STLSTCLIN--QILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194
S C+ N QIL + E C KE S MW+YV +GN++RG+GETPI+PLG+S
Sbjct: 127 SNSFLCMENGTQILRPTQDPSE-----CTKEVKSLMWVYVLVGNIVRGMGETPILPLGIS 181
Query: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254
YI+DFAK +S LY+G++ A+IGP+IG L S + +YVD G+V+ + ITPTD+RW
Sbjct: 182 YIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRW 241
Query: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314
VGAWW FL+ +++++IPFFFLP T K E A +++ +E Q + +
Sbjct: 242 VGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD----IIKNENEDKQKEEVKKE 297
Query: 315 GKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKA 374
ITK+ F KS+ NP+Y++F+L++++Q ++++ +++ KY+EQQYG SS A
Sbjct: 298 KYGITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
Query: 375 NILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKS 434
L+G+ +P G +GG I+KKFK+ A C+ +++ Y L F + CEN S
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 435 VAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG 494
V G+ +Y+G + + CN DCNC W+PVCGNNG++Y+S CLAGC++S G
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
Query: 495 NKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTS 554
+VF NCSC++ +G N SA LG C + C+ +F+ + ++ F +L
Sbjct: 475 TGINMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
Query: 555 HVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCR 614
M++++ ++ E KSL +G H+ R GI APIYFGAL+D+TC+ W T CG G+CR
Sbjct: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
Query: 615 TYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKK 649
Y+ST+F +YLGL + LR SS V +I++ ++K
Sbjct: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 540 bits (1392), Expect = e-153
Identities = 274/642 (42%), Positives = 398/642 (61%), Gaps = 51/642 (7%)
Query: 15 PSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFE 74
PS +K C LK+FL ALS + AK L +KS+I IERRF+I SSLVG IDGSFE
Sbjct: 30 PSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFE 89
Query: 75 IGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSEN 134
IGNLLVI FVSYFG+KLHRPK+IG GC IMG+G +L A+P FFM Y+Y + + S N
Sbjct: 90 IGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER---YSPSSN 146
Query: 135 STSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194
ST ++S CL+ ES S + + V
Sbjct: 147 STLSISPCLL--------------------ESSSQLPVSVM------------------- 167
Query: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254
++ S + G + +A+IGPI GF LGSL +K+YVDIG+V+L I ITP D +W
Sbjct: 168 ------EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQW 221
Query: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314
VGAWWL +L++G+ S+++++PF++LP++ + Q ++ S + + D T T Q
Sbjct: 222 VGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQ 280
Query: 315 GKN--ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSS 372
G+N I + F S K++ NP+Y +++ + +Q +S G TY KY+EQQYGQ SS
Sbjct: 281 GENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSS 340
Query: 373 KANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCEN 432
+AN ++G+I IP A G+F GG ++KKF+++ G AK ++V +L F + CEN
Sbjct: 341 RANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCEN 400
Query: 433 KSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSS 492
VAGLT++Y G PV+ H S CNS C C E++WEP+CG NGITY+S CLAGC++S
Sbjct: 401 SDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTS 460
Query: 493 SGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGG 552
+ + K I+FYNC+C+ + ++ N S +G C +D+ C + F +F+ I V+ + +LGG
Sbjct: 461 NRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGG 520
Query: 553 TSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGS 612
+L+++ ++P+LKS ALG +++ IR L GI AP+YFG LIDT+C+KW CG+RGS
Sbjct: 521 IPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGS 580
Query: 613 CRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEK 654
CR Y+S F +YLGL+ +L S++L I +++ +KK Y K
Sbjct: 581 CRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 622
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 491 bits (1263), Expect = e-138
Identities = 246/595 (41%), Positives = 366/595 (61%), Gaps = 39/595 (6%)
Query: 104 MGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQI----LSLNRASPEIVG 159
MG+G +L A+P FFM Y+Y + + S NST ++S CL+ +S+ S +
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYER---YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKIS 57
Query: 160 KGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIG 219
C ++ S MWIYVF+GN+LRGIGETPI PLG++Y+DDFA E +++ Y+G + +A+IG
Sbjct: 58 NECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 117
Query: 220 PIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFL 279
PI GF LGSL +K+YVDIG+V+L I ITP D +WVGAWWL +L++G+ S+++++PF++L
Sbjct: 118 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 177
Query: 280 PQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKN--ITKNVTGFFQSFKSILTNPL 337
P++ + Q ++ S + + D T T QG+N I + F S K++ NP+
Sbjct: 178 PKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPV 236
Query: 338 YVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYII 397
Y +++ + +Q +S G TY KY+EQQYGQ SS+AN ++G+I IP A G+F GG ++
Sbjct: 237 YFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVM 296
Query: 398 KKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLS 457
KKF+++ G AK ++V +L F + CEN VAGLT++Y G PV+ H S
Sbjct: 297 KKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFS 356
Query: 458 YCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNY 517
CNS C C E++WEP+CG NGITY+S CLAGC++S+ + K I+FYNC+C+ + ++ N
Sbjct: 357 DCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNS 416
Query: 518 SAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSM 577
S +G C +D+ C + F +F+ I V+ + +LGG +L+++ ++P+LKS ALG +++
Sbjct: 417 SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTL 476
Query: 578 VIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSL 637
IR L GI AP+YFG LIDT+C+KW CG+RGSCR Y+S F
Sbjct: 477 AIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVF---------------- 520
Query: 638 VLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNK-NKHFVPSAGADSETHC 691
+YQ K I AS S+ D N NK + HF S T+C
Sbjct: 521 ------------RYQIKSIPASHCYSIPDLHNATDTNKFSCHFTACKTYISGTNC 563
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 385 bits (990), Expect = e-107
Identities = 229/658 (34%), Positives = 363/658 (55%), Gaps = 43/658 (6%)
Query: 12 EAQPSENKKTRYC--NGLKMFLAALSLSFIAK-TLGAIIMKSSIIHIERRFEISSSLVGF 68
EAQ ++ KK + + +K+FL + +A+ T+GA ++ S + +ERRF + S+ VG
Sbjct: 22 EAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLV-SVLTTLERRFNLQSADVGV 80
Query: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETN 128
I SFEIGNL +I+FVSYFG++ HRP+LIG G +M +G +L+ALP F Y+Y
Sbjct: 81 IASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEI 140
Query: 129 INSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPI 188
+E C N P+++ + + + + M++ + +L GIG TP+
Sbjct: 141 RWGAEGR----DVCAANGSGGDEGPDPDLICRN--RTATNMMYLLLIGAQVLLGIGATPV 194
Query: 189 VPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRIT 248
PLG+SYIDD + SSLY+GIL + + GP GF LGS +K+YVD ++D S + IT
Sbjct: 195 QPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDIT 254
Query: 249 PTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQT---PNKPQKERKASL----------- 294
P D RW+GAWW FL+ G SS+ F PQ+ ++P E + ++
Sbjct: 255 PDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKP 314
Query: 295 SLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIG 354
S VL E D +A+ Q + I K VT K +L+NP++ +L ++++ G
Sbjct: 315 SNGVLRHPLEPDSSASCFQQLRVIPK-VT------KHLLSNPVFTCIILAACMEIAVVAG 367
Query: 355 AFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFT 414
++ KY+EQQ+ +S AN LLG+ IP G+FLGG ++KK L+ +G + +
Sbjct: 368 FAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLV 427
Query: 415 AVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVC 474
++S + Y+ + F+ C+ VAG+T+ Y GN+ P S CN++C C + PVC
Sbjct: 428 NLVSTACYVSFLFLGCDTGPVAGVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVC 486
Query: 475 GNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKF 534
G +GITY+S C AGC S++ C+CL T + N + G+CP C F
Sbjct: 487 GADGITYLSACFAGCNSTN-------LTGCACL--TTVPAENATVVPGKCP-SPGCQEAF 536
Query: 535 YFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGAL 594
F+ + + A+ T V+++++ V PELKS ALG +++R LG I P+ FGA
Sbjct: 537 LTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAG 596
Query: 595 IDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQ 652
ID+TC+ WST CG +G+C Y++ + +Y+ ++ L+ + +LY ++K Y+
Sbjct: 597 IDSTCLFWST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 385 bits (990), Expect = e-107
Identities = 229/658 (34%), Positives = 363/658 (55%), Gaps = 43/658 (6%)
Query: 12 EAQPSENKKTRYC--NGLKMFLAALSLSFIAK-TLGAIIMKSSIIHIERRFEISSSLVGF 68
EAQ ++ KK + + +K+FL + +A+ T+GA ++ S + +ERRF + S+ VG
Sbjct: 22 EAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLV-SVLTTLERRFNLQSADVGV 80
Query: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETN 128
I SFEIGNL +I+FVSYFG++ HRP+LIG G +M +G +L+ALP F Y+Y
Sbjct: 81 IASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEI 140
Query: 129 INSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPI 188
+E C N P+++ + + + + M++ + +L GIG TP+
Sbjct: 141 RWGAEGR----DVCAANGSGGDEGPDPDLICRN--RTATNMMYLLLIGAQVLLGIGATPV 194
Query: 189 VPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRIT 248
PLG+SYIDD + SSLY+GIL + + GP GF LGS +K+YVD ++D S + IT
Sbjct: 195 QPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDIT 254
Query: 249 PTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQT---PNKPQKERKASL----------- 294
P D RW+GAWW FL+ G SS+ F PQ+ ++P E + ++
Sbjct: 255 PDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKP 314
Query: 295 SLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIG 354
S VL E D +A+ Q + I K VT K +L+NP++ +L ++++ G
Sbjct: 315 SNGVLRHPLEPDSSASCFQQLRVIPK-VT------KHLLSNPVFTCIILAACMEIAVVAG 367
Query: 355 AFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFT 414
++ KY+EQQ+ +S AN LLG+ IP G+FLGG ++KK L+ +G + +
Sbjct: 368 FAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLV 427
Query: 415 AVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVC 474
++S + Y+ + F+ C+ VAG+T+ Y GN+ P S CN++C C + PVC
Sbjct: 428 NLVSTACYVSFLFLGCDTGPVAGVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVC 486
Query: 475 GNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKF 534
G +GITY+S C AGC S++ C+CL T + N + G+CP C F
Sbjct: 487 GADGITYLSACFAGCNSTN-------LTGCACL--TTVPAENATVVPGKCP-SPGCQEAF 536
Query: 535 YFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGAL 594
F+ + + A+ T V+++++ V PELKS ALG +++R LG I P+ FGA
Sbjct: 537 LTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAG 596
Query: 595 IDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQ 652
ID+TC+ WST CG +G+C Y++ + +Y+ ++ L+ + +LY ++K Y+
Sbjct: 597 IDSTCLFWST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 353 bits (907), Expect = 2e-97
Identities = 210/629 (33%), Positives = 335/629 (53%), Gaps = 35/629 (5%)
Query: 27 LKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSY 86
+K+F+ L + + L + KSS+ IE+RF +SSS G I EI N ++I+FVSY
Sbjct: 31 IKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSY 90
Query: 87 FGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQ 146
FGS++HRP+LIGIG + G + LPHF Y+Y+ + S+ N++ +
Sbjct: 91 FGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYT----LASTGNNSRLQAELCQKH 146
Query: 147 ILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSS 206
L + + KE+ S MW + + +L GIG PI P G+SY+DDF++ +S
Sbjct: 147 WQDLPPSKCHSTTQNPQKETSS-MWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSP 205
Query: 207 LYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSG 266
LY+ IL AI++ GP G+ LGS+ +++VD G V+ + + + P D RW+GAWWL L+S
Sbjct: 206 LYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISS 265
Query: 267 LFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFF 326
+++S PFFF P+ K A T DE + ++G ++ + F
Sbjct: 266 ALLVLTSFPFFFFPRAMPIGAKRAPA--------TADEARKLEEAKSRG-SLVDFIKRFP 316
Query: 327 QSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIF 386
F +L N L+V+ VL S G T++ K++E+QYG ++ AN L+G + +P
Sbjct: 317 CIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAA 376
Query: 387 ASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNN 446
A GM GG ++K+F + I + + +S+ + FF+ C +VA + Y +
Sbjct: 377 ALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEV---YPPST 433
Query: 447 PVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKS---SSGNKKPIVFYN 503
+ H P C DC+C +S + PVCG+NGI Y+SPC AGC + SS K +++ N
Sbjct: 434 SSSIHPQSPA--CRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLN 491
Query: 504 CSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSH---VMLIV 560
CSC VTG + SA G CP A +F + L F S + SH M+++
Sbjct: 492 CSC--VTG---GSASAKTGSCPVPCA-----HFLLPAIFLISFVSLIACISHNPLYMMVL 541
Query: 561 KIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTS 620
++V E KS A+G +++R L + +P +G ID +CI+W++ G RG+C Y++ +
Sbjct: 542 RVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDA 601
Query: 621 FSRVYLGLSSMLRVSSLVLYIILIYAMKK 649
YLGL + ++L + + +KK
Sbjct: 602 LRDRYLGLQMGYKALGMLLLCFISWRVKK 630
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 341 bits (875), Expect = 1e-93
Identities = 204/663 (30%), Positives = 344/663 (51%), Gaps = 55/663 (8%)
Query: 24 CNGLKMFLAALSLSFIAKTLGAII---MKSSIIHIERRFEISSSLVGFIDGSFEIGNLLV 80
CN FL L +A T G ++ + SI +E+R+E+ SSL G I S++I L+
Sbjct: 101 CNTPGGFL--LHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLL 158
Query: 81 IVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSK--ETNINSSENSTST 138
+FVS+FG + H+P+ + F++G+G ++ +LP FF G Y+ E ++ NSTS
Sbjct: 159 SLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSC 218
Query: 139 LSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDD 198
S+ +Y+++++ +G +L G G TP+ LG +++DD
Sbjct: 219 TSST---------------------SSLSNYLYVFI-LGQLLLGAGGTPLYTLGTAFLDD 256
Query: 199 FAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAW 258
SSLY+G A++++GP IG+ LG +Y+D+ + + + T D RW+GAW
Sbjct: 257 SVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDV--TEDDPRWLGAW 314
Query: 259 WLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNI 318
W+ FL+S +F+ IPF P K + + +T+ +N +
Sbjct: 315 WIGFLLSWIFAWSLIIPFSCFP-------KHLPGTAEIQAGKTSQAHQSNSNADVK---F 364
Query: 319 TKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILL 378
K++ F + K+++ N +++ VL T + G T++ K++E Q+G SS A L
Sbjct: 365 GKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLG 424
Query: 379 GVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGL 438
G + IP A G LGG+++ KF++ KF+ FT+ ++L+ ++ + CEN+ AG+
Sbjct: 425 GAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGV 484
Query: 439 TMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKP 498
+ +Y+G T ++ CN++CNC S + PVCG +G+ Y SPC AGC + ++KP
Sbjct: 485 SESYNG----TGELGNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKP 539
Query: 499 IVFYNCSCLE-----VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGT 553
V+YNCSC+E + + + A G+C A K F+ I + + F+ + GT
Sbjct: 540 KVYYNCSCIERKTEITSTAETFGFEAKAGKCETHCA---KLPIFLCIFFIVIIFTFMAGT 596
Query: 554 SHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSC 613
+ I++ V +SLALG MV+R LG I PI FG ID+TCI W N+CG +G+C
Sbjct: 597 PITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGAC 656
Query: 614 RTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDIN-ASENGSVMDEANLES 672
Y++ + + + +S +V ++ I+ K D++ EN V + +
Sbjct: 657 WIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQD 716
Query: 673 LNK 675
LNK
Sbjct: 717 LNK 719
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 331 bits (849), Expect = 1e-90
Identities = 213/690 (30%), Positives = 348/690 (50%), Gaps = 52/690 (7%)
Query: 11 AEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFID 70
A P + + + + N +K+F+ SL +A+ + + +KSSI +E+RF +SS G +
Sbjct: 11 ASPDPQDVRPSVFHN-IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLA 69
Query: 71 GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNIN 130
E+GN +IVFVSYFGS++HRP++IG G ++ + G+L LPHF YRY
Sbjct: 70 SFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN----T 125
Query: 131 SSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYV-FMGNMLRGIGETPIV 189
S E+ L S ++P E+ + + F+ L G+G PI
Sbjct: 126 SPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQ 185
Query: 190 PLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITP 249
P G+SYIDDFA +S LYLGIL A+ M+GP + F LGSL ++YVDI + I +T
Sbjct: 186 PFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTI 245
Query: 250 TDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDE----- 304
D RWVGAWWL FL++ +++IP+FF P+ P+++R+ VL D
Sbjct: 246 KDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKG 303
Query: 305 KDQTA------------NLTNQGKNITKNVTGFFQSFKSI----LTNPLYVMFVLLTLLQ 348
KD + L N+T V F + F + L +P++++ VL +
Sbjct: 304 KDSPSKQSPGESTKKQDGLVQIAPNLT--VIQFIKVFPRVLLQTLRHPIFLLVVLSQVCL 361
Query: 349 VSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIA 408
S G T++ K++E+Q+ +S AN+L+G ++ P G+ +GG ++K+ L VG
Sbjct: 362 SSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCG 421
Query: 409 KFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLS-YCNSDCNCDE 467
++ L F L FFI C + +AG+T + ++H + LS C C+C
Sbjct: 422 ALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPL 475
Query: 468 SQWEPVCG-NNGITYISPCLAGCKS----SSGNKKPIVFYNCSCLEVTGLQNRNYSAHLG 522
+ PVC + + YI+PC AGC S + + + + NCSC+ G
Sbjct: 476 DGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAG 529
Query: 523 ECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRAL 582
C D C+ F+ + L + L T MLI++ V+ E K+LA+G M +R L
Sbjct: 530 SC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRIL 587
Query: 583 GGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYII 642
+ +P+ G+ IDTTC+ W+ +CG R CR YN+ ++GL + S++ + +
Sbjct: 588 AWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFAL 646
Query: 643 LIYAMKKKYQEKDINASENGSVMDEANLES 672
++ ++++ +E S + +++ L S
Sbjct: 647 VLAVLRQQDKEARTKESRSSPAVEQQLLVS 676
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 331 bits (849), Expect = 1e-90
Identities = 213/690 (30%), Positives = 348/690 (50%), Gaps = 52/690 (7%)
Query: 11 AEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFID 70
A P + + + + N +K+F+ SL +A+ + + +KSSI +E+RF +SS G +
Sbjct: 33 ASPDPQDVRPSVFHN-IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLA 91
Query: 71 GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNIN 130
E+GN +IVFVSYFGS++HRP++IG G ++ + G+L LPHF YRY
Sbjct: 92 SFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN----T 147
Query: 131 SSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYV-FMGNMLRGIGETPIV 189
S E+ L S ++P E+ + + F+ L G+G PI
Sbjct: 148 SPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQ 207
Query: 190 PLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITP 249
P G+SYIDDFA +S LYLGIL A+ M+GP + F LGSL ++YVDI + I +T
Sbjct: 208 PFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTI 267
Query: 250 TDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDE----- 304
D RWVGAWWL FL++ +++IP+FF P+ P+++R+ VL D
Sbjct: 268 KDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKG 325
Query: 305 KDQTA------------NLTNQGKNITKNVTGFFQSFKSI----LTNPLYVMFVLLTLLQ 348
KD + L N+T V F + F + L +P++++ VL +
Sbjct: 326 KDSPSKQSPGESTKKQDGLVQIAPNLT--VIQFIKVFPRVLLQTLRHPIFLLVVLSQVCL 383
Query: 349 VSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIA 408
S G T++ K++E+Q+ +S AN+L+G ++ P G+ +GG ++K+ L VG
Sbjct: 384 SSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCG 443
Query: 409 KFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLS-YCNSDCNCDE 467
++ L F L FFI C + +AG+T + ++H + LS C C+C
Sbjct: 444 ALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPL 497
Query: 468 SQWEPVCG-NNGITYISPCLAGCKS----SSGNKKPIVFYNCSCLEVTGLQNRNYSAHLG 522
+ PVC + + YI+PC AGC S + + + + NCSC+ G
Sbjct: 498 DGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAG 551
Query: 523 ECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRAL 582
C D C+ F+ + L + L T MLI++ V+ E K+LA+G M +R L
Sbjct: 552 SC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRIL 609
Query: 583 GGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYII 642
+ +P+ G+ IDTTC+ W+ +CG R CR YN+ ++GL + S++ + +
Sbjct: 610 AWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFAL 668
Query: 643 LIYAMKKKYQEKDINASENGSVMDEANLES 672
++ ++++ +E S + +++ L S
Sbjct: 669 VLAVLRQQDKEARTKESRSSPAVEQQLLVS 698
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 330 bits (845), Expect = 4e-90
Identities = 218/656 (33%), Positives = 340/656 (51%), Gaps = 70/656 (10%)
Query: 36 LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95
L+FI + + + S I IERR+ + SS G + F+IGNL+V+VFVSYFG + RP
Sbjct: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
Query: 96 LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148
+ +G ++ G L ALPHF Y+ +E N ++ NST+TL
Sbjct: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
Query: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204
C K+SG + W+YV + +L G+G TPI LG +Y+DD K+ +
Sbjct: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
Query: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264
SSLYL I+ + +GP +G+ LG L YVD + + + D R++G WW FL+
Sbjct: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
Query: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQG-KNIT--- 319
+ + P F P+ P + +K++K S+ + +D + +N + Q K ++
Sbjct: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMG 413
Query: 320 --KNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAF-TYVFKYVEQQYGQPSSKANI 376
K+V ++ IL+N + +FV L+ S+ + AF T++ K++E Q+G P+S A+I
Sbjct: 414 FGKDVRDLPRAAVRILSNMTF-LFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASI 472
Query: 377 LLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVA 436
GVI +P G+ LGGYIIKK KL AK + + +SL + F + CE+ ++
Sbjct: 473 YTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLG 532
Query: 437 GLTMTYDGNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGN 495
G+ + Y +T HR++ S CN +C C ++EPVCG++GITY +PCLAGC +S
Sbjct: 533 GINIPYTTGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591
Query: 496 KKPIVFY-NCSCLE--------------------VTGLQNRNYSAHLGECPRDDACTRKF 534
I Y C+C++ V N N A G+C R C
Sbjct: 592 STGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLI 649
Query: 535 YFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGAL 594
F V + ++ F +A S +++ ++ V+ E + ALG +++R L I PIYFGA+
Sbjct: 650 PFLVFLFIVT-FITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAV 708
Query: 595 IDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKK 650
IDTTC+ W CG +GSC YN TSF VY GL++ L+ + + Y++K K
Sbjct: 709 IDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYK 763
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 287 bits (734), Expect = 3e-77
Identities = 187/638 (29%), Positives = 305/638 (47%), Gaps = 52/638 (8%)
Query: 26 GLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVS 85
G+ FL A + T+ I + I +ERR+++ S G I S++I L + FVS
Sbjct: 104 GILFFLCAAAF-LQGMTVNGFI-NTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVS 161
Query: 86 YFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLIN 145
YFG H+P+ +G G +MG G ++ ALPHF G Y + +
Sbjct: 162 YFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGV---------------- 205
Query: 146 QILSLNRASPEIVGKGCL-KESGSYMWIYVFM-GNMLRGIGETPIVPLGLSYIDDFAKEG 203
R P G C SG + VFM G L G+G TP+ LG++Y+D+ K
Sbjct: 206 ------RTCPANPGAVCADSTSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSS 259
Query: 204 HSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFL 263
S +Y+ I A++GP G+ +G +Y ++G +T WVGAWW+ FL
Sbjct: 260 CSPVYIAIFYTAAILGPAAGYLIGGALLNIYTEMG----RRTELTTESPLWVGAWWVGFL 315
Query: 264 VSGLFSIISSIPFFFLP-QTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNV 322
SG + +++P P Q P + + +H L+ + + + + K +
Sbjct: 316 GSGAAAFFTAVPILGYPRQLPGSQRYAVMRAAEMHQLKDSSRGEAS------NPDFGKTI 369
Query: 323 TGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVIT 382
S +L NP +++ L + + G T+ K++E Q+ +S+A L G +
Sbjct: 370 RDLPLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLV 429
Query: 383 IPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTY 442
+P G FLGG+ + K +L + KF F V+SL +L F + C + +AG+T +Y
Sbjct: 430 VPAGGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSL-LGILVFSLHCPSVPMAGVTASY 488
Query: 443 DGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSS-----GNKK 497
G+ H ++ + CN+ C+C + PVCG++G+ Y S C AGC +++ G K
Sbjct: 489 GGSLLPEGHLNL-TAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQK- 546
Query: 498 PIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVM 557
V+ +CSC+ L + A G+C C RK V I V+ +FF+ L +
Sbjct: 547 --VYRDCSCIP-QNLSSGFGHATAGKC--TSTCQRKPLLLVFIFVV-IFFTFLSSIPALT 600
Query: 558 LIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYN 617
++ V+ +S ALG +V+R LGGI PI FG +ID C+ W + CG +GSC Y
Sbjct: 601 ATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQ 659
Query: 618 STSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKD 655
+++ SR L + + +V ++ + I + K + D
Sbjct: 660 NSAMSRYILIMGLLYKVLGVLFFAIACFLYKPLSESSD 697
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 286 bits (732), Expect = 4e-77
Identities = 199/649 (30%), Positives = 307/649 (47%), Gaps = 111/649 (17%)
Query: 36 LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95
L+FI + + + S I IERR+ + SS G + F+IGNL+V+VFVSYFG + RP
Sbjct: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
Query: 96 LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148
+ +G ++ G L ALPHF Y+ +E N ++ NST+TL
Sbjct: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
Query: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204
C K+SG + W+YV + +L G+G TPI LG +Y+DD K+ +
Sbjct: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
Query: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264
SSLYL I+ + +GP +G+ LG L YVD + + + D R++G WW FL+
Sbjct: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
Query: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVT 323
+ + P F P+ P + +K++K S+ + +D + +N + Q ++
Sbjct: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSM- 412
Query: 324 GFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITI 383
GF + + GVI +
Sbjct: 413 GFGKDVR------------------------------------------------GVIIV 424
Query: 384 PIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYD 443
P G+ LGGYIIKK KL AK + + +SL + F + CE+ ++ G+ + Y
Sbjct: 425 PSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYT 484
Query: 444 GNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFY 502
+T HR++ S CN +C C ++EPVCG++GITY +PCLAGC +S I Y
Sbjct: 485 TGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNY 543
Query: 503 -NCSCLE--------------------VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQ 541
C+C++ V N N A G+C R C F V +
Sbjct: 544 TECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIPFLVFLF 601
Query: 542 VLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIK 601
++ F +A S +++ ++ V+ E + ALG +++R L I PIYFGA+IDTTC+
Sbjct: 602 IVT-FITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCML 660
Query: 602 WSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKK 650
W CG +GSC YN TSF VY GL++ L+ + + Y++K K
Sbjct: 661 WQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYK 708
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 259 bits (663), Expect = 4e-69
Identities = 167/494 (33%), Positives = 264/494 (53%), Gaps = 46/494 (9%)
Query: 36 LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95
L+FI + + + S I IERR+ + SS G + F+IGNL+V+VFVSYFG + RP
Sbjct: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
Query: 96 LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148
+ +G ++ G L ALPHF Y+ +E N ++ NST+TL
Sbjct: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
Query: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204
C K+SG + W+YV + +L G+G TPI LG +Y+DD K+ +
Sbjct: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
Query: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264
SSLYL I+ + +GP +G+ LG L YVD + + + D R++G WW FL+
Sbjct: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
Query: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQG-KNIT--- 319
+ + P F P+ P + +K++K S+ + +D + +N + Q K ++
Sbjct: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMG 413
Query: 320 --KNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAF-TYVFKYVEQQYGQPSSKANI 376
K+V ++ IL+N + +FV L+ S+ + AF T++ K++E Q+G P+S A+I
Sbjct: 414 FGKDVRDLPRAAVRILSNMTF-LFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASI 472
Query: 377 LLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVA 436
GVI +P G+ LGGYIIKK KL AK + + +SL + F + CE+ ++
Sbjct: 473 YTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLG 532
Query: 437 GLTMTYDGNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGN 495
G+ + Y +T HR++ S CN +C C ++EPVCG++GITY +PCLAGC +S
Sbjct: 533 GINIPYTTGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591
Query: 496 KKPIVFY-NCSCLE 508
I Y C+C++
Sbjct: 592 STGIRNYTECTCVQ 605
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 258 bits (659), Expect = 1e-68
Identities = 162/526 (30%), Positives = 266/526 (50%), Gaps = 46/526 (8%)
Query: 174 VFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKM 233
+F+ L G+G PI P G+SYIDDFA +S LYLGIL A+ M+GP + F LGSL ++
Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
Query: 234 YVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKAS 293
YVDI + I +T D RWVGAWWL FL++ +++IP+FF P+ P+++R+
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQ 165
Query: 294 LSLHVLETNDE-----KDQTA------------NLTNQGKNITKNVTGFFQSFKSI---- 332
VL D KD + L N+T V F + F +
Sbjct: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT--VIQFIKVFPRVLLQT 223
Query: 333 LTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFL 392
L +P++++ VL + S G T++ K++E+Q+ +S AN+L+G ++ P G+ +
Sbjct: 224 LRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVV 283
Query: 393 GGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHR 452
GG ++K+ L VG ++ L F L FFI C + +AG+T + ++H
Sbjct: 284 GGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHP 337
Query: 453 DVPLS-YCNSDCNCDESQWEPVCG-NNGITYISPCLAGCKS----SSGNKKPIVFYNCSC 506
+ LS C C+C + PVC + + YI+PC AGC S + + + + NCSC
Sbjct: 338 GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSC 397
Query: 507 LEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPE 566
+ G C D C+ F+ + L + L T MLI++ V+ E
Sbjct: 398 VV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKE 449
Query: 567 LKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYL 626
K+LA+G M +R L + +P+ G+ IDTTC+ W+ +CG R CR YN+ ++
Sbjct: 450 DKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFI 508
Query: 627 GLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLES 672
GL + S++ + +++ ++++ +E S + +++ L S
Sbjct: 509 GLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVS 554
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 229 bits (585), Expect = 5e-60
Identities = 155/640 (24%), Positives = 283/640 (44%), Gaps = 54/640 (8%)
Query: 24 CNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVF 83
CN ++ F+ + I + + ++ SI ++ +++ + ++ S++I + LV +F
Sbjct: 102 CNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIF 161
Query: 84 VSYFGSKLHRPKLIGI--GCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLST 141
++++G R K+I F++G+G +L A P N + ++
Sbjct: 162 IAFYGD---RKKVIWFVASSFLIGLGSLLCAFPSI-----------NEENKQSKVGIEDI 207
Query: 142 CLINQILSLNRASPEIVGKGCLKESGSYMWIYV---FMGNMLRGIGETPIVPLGLSYIDD 198
C +++S GC S+ Y+ +G ++GI P+ LG+++ID+
Sbjct: 208 CEEIKVVS-----------GCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDE 256
Query: 199 FAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAW 258
+ +YLGI +MIG +G+ LG+ K V + + W+ W
Sbjct: 257 NVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTW 314
Query: 259 WLNFLVSGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQGKN 317
W+NFL + + + + IP P P + + + LH ++ +
Sbjct: 315 WINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFFDSR----------LKDLK 364
Query: 318 ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANIL 377
+ N+ + ++ NP+ + L + IGA ++ Y+E Q+ + A L
Sbjct: 365 LGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTL 424
Query: 378 LGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAG 437
G++ IP A G LGG I+ +++ + +F T+V+SL + F+ C AG
Sbjct: 425 AGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAG 484
Query: 438 LTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKK 497
+ YDG + + P CN C C S + +CG + I Y SPC AGC S +
Sbjct: 485 INEDYDGTGKL-GNLTAP---CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
Query: 498 PIVFYNCSCLE----VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGT 553
++YNCSC++ + A G+C DA K F+A L FS G
Sbjct: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKC---DAKCYKLPLFIAFIFSTLIFSGFSGV 597
Query: 554 SHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSC 613
V+ + ++V +L+SLALG +++R G I P F +T+CI N CG G C
Sbjct: 598 PIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRC 657
Query: 614 RTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQE 653
YN T + + +G+ + ++ +++ I + K++ E
Sbjct: 658 WIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRRLNE 697
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 38.1 bits (87), Expect = 0.027
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 450 SHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGC 489
S D ++ CNC + Q+ PVCG NG TY S C+A C
Sbjct: 620 SSEDDRRTFTGLPCNCAD-QFVPVCGQNGRTYPSACIARC 658
Score = 30.0 bits (66), Expect = 7.5
Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 8/47 (17%)
Query: 445 NNPVTSH-RDVPLSY---CNSDCNCDESQWEPVCGNNGITYISPCLA 487
NN T + R LSY C C E PVCG+NG TY S C A
Sbjct: 732 NNLCTLYQRGKSLSYKGPCQPFCRATE----PVCGHNGETYSSVCAA 774
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 37.7 bits (86), Expect = 0.036
Identities = 58/233 (24%), Positives = 94/233 (40%), Gaps = 18/233 (7%)
Query: 172 IYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIA--MIGPIIGFTL-GS 228
I +G +L G + LG S+I A S LY G+++ + IG I L G+
Sbjct: 133 ILSLVGALLMGFSK-----LGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGA 187
Query: 229 L--FSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPN-- 284
L F ++ + G + I + + W + +SG+ +I+ S+ FF P++P
Sbjct: 188 LGTFHQLAIVTGILISQIIGLEFILGNY-DLWHILLGLSGVRAILQSLLLFFCPESPRYL 246
Query: 285 --KPQKERKASLSLHVLETNDE--KDQTANLTNQGKNITKNVTGFFQSF-KSILTNPLYV 339
K +E KA SL L D+ KD + + ++ Q F S P+ V
Sbjct: 247 YIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILV 306
Query: 340 MFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFL 392
+L Q S G F Y + A I +G + + A +FL
Sbjct: 307 ALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFL 359
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 451 HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYN 503
+ V LS+ N N ++P+CG N ITY +PC+ C S + I FY+
Sbjct: 42 YEKVNLSWYNGTVNPCPGLYQPICGTNFITYDNPCIL-CVESLKSHGRIRFYH 93
>gi|66082554 low density lipoprotein receptor-related protein 8
isoform 2 precursor [Homo sapiens]
Length = 793
Score = 35.4 bits (80), Expect = 0.18
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 10/88 (11%)
Query: 449 TSHRDVPLSY-CNSDCNCDESQWEPVCGNNGITYISPCL---AGCKSSSGNKKPIVFYNC 504
TSH+ VP S+ C+ + +C+ E C T+++ CL GC + K + + C
Sbjct: 137 TSHKCVPASWRCDGEKDCEGGADEAGCA----TWLNECLHNNGGCSHICTDLK--IGFEC 190
Query: 505 SCLEVTGLQNRNYSAHLGECPRDDACTR 532
+C L ++ + EC DAC++
Sbjct: 191 TCPAGFQLLDQKTCGDIDECKDPDACSQ 218
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 33.5 bits (75), Expect = 0.68
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 459 CNSDCNCDESQWEPVCGNNGITYISPC---LAGCKSSSG 494
C D +C PVCG++G+TY + C A C+S G
Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741
Score = 29.6 bits (65), Expect = 9.8
Identities = 12/26 (46%), Positives = 18/26 (69%), Gaps = 3/26 (11%)
Query: 463 CNCDE---SQWEPVCGNNGITYISPC 485
C C + S ++PVCG++G+TY S C
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|13236549 major facilitator superfamily domain containing 11
[Homo sapiens]
Length = 449
Score = 33.1 bits (74), Expect = 0.88
Identities = 28/113 (24%), Positives = 55/113 (48%), Gaps = 17/113 (15%)
Query: 246 RITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEK 305
+I+ +D R V F+ + S++ ++ FF + KP E E++D++
Sbjct: 163 QISESDRRTV------FIALTVISLVGTVLFFLI----RKPDSENVLGED----ESSDDQ 208
Query: 306 DQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFV--LLTLLQVSSYIGAF 356
D N + Q N+TK V F +SFK +T + ++ + T L+++ + G +
Sbjct: 209 DMEVNESAQN-NLTKAVDAFKKSFKLCVTKEMLLLSITTAYTGLELTFFSGVY 260
>gi|223717983 solute carrier family 37 (glycerol-3-phosphate
transporter), member 2 isoform 2 [Homo sapiens]
Length = 501
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 25/115 (21%)
Query: 170 MWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSL 229
+W +V + + G+ +T P ++ + ++ +G +GI N+ +G I LGSL
Sbjct: 143 LWYFVVI-QVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNI----LGSL 197
Query: 230 FSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLF-SIISSIPFFFLPQTP 283
+ ++V+ G W L+F+V G+ +++ I F FL + P
Sbjct: 198 IAGIWVN-------------------GQWGLSFIVPGIITAVMGVITFLFLIEHP 233
>gi|38093649 solute carrier family 37 (glycerol-3-phosphate
transporter), member 2 isoform 1 [Homo sapiens]
Length = 505
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 25/115 (21%)
Query: 170 MWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSL 229
+W +V + + G+ +T P ++ + ++ +G +GI N+ +G I LGSL
Sbjct: 143 LWYFVVI-QVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNI----LGSL 197
Query: 230 FSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLF-SIISSIPFFFLPQTP 283
+ ++V+ G W L+F+V G+ +++ I F FL + P
Sbjct: 198 IAGIWVN-------------------GQWGLSFIVPGIITAVMGVITFLFLIEHP 233
>gi|73747917 transporter 2, ATP-binding cassette, sub-family B
isoform 2 [Homo sapiens]
Length = 653
Score = 32.7 bits (73), Expect = 1.2
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 21/97 (21%)
Query: 559 IVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDT----------------TCI-- 600
++K+ +P+L L F +V+ LG L P Y G +ID C+
Sbjct: 141 LLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFS 200
Query: 601 KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSL 637
S+ + G RG C TY + SR+ L + L S L
Sbjct: 201 FGSSLSAGCRGGCFTY---TMSRINLRIREQLFSSLL 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,918,234
Number of Sequences: 37866
Number of extensions: 1022618
Number of successful extensions: 2314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 75
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.