BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|225543407 BTB domain protein BDPL [Homo sapiens] (485 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|225543407 BTB domain protein BDPL [Homo sapiens] 977 0.0 gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo s... 700 0.0 gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo ... 700 0.0 gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens] 405 e-113 gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens] 382 e-106 gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens] 291 7e-79 gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 103 3e-22 gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 103 3e-22 gi|42741669 kelch repeat and BTB (POZ) domain containing 10 [Hom... 87 3e-17 gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens] 84 4e-16 gi|211904190 hypothetical protein LOC149478 [Homo sapiens] 82 8e-16 gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo... 80 4e-15 gi|148664209 kelch-like 10 [Homo sapiens] 79 9e-15 gi|170784846 kelch-like 7 isoform 1 [Homo sapiens] 77 5e-14 gi|170784844 kelch-like 7 isoform 2 [Homo sapiens] 77 5e-14 gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo... 75 1e-13 gi|45269145 kelch-like ECH-associated protein 1 [Homo sapiens] 75 1e-13 gi|22027642 kelch-like ECH-associated protein 1 [Homo sapiens] 75 1e-13 gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Hom... 75 1e-13 gi|40807500 kelch-like 20 [Homo sapiens] 75 1e-13 gi|128485503 kelch-like 30 [Homo sapiens] 71 2e-12 gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens] 71 3e-12 gi|38194229 kelch-like 17 [Homo sapiens] 70 6e-12 gi|194097389 kelch-like 38 [Homo sapiens] 68 2e-11 gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 68 2e-11 gi|34101268 kelch-like 8 [Homo sapiens] 67 4e-11 gi|126116565 MYC binding protein 2 [Homo sapiens] 67 5e-11 gi|166235129 kelch-like 3 [Homo sapiens] 67 5e-11 gi|55925604 kelch-like 18 [Homo sapiens] 65 1e-10 gi|227497736 T-cell activation kelch repeat protein [Homo sapiens] 64 3e-10 >gi|225543407 BTB domain protein BDPL [Homo sapiens] Length = 485 Score = 977 bits (2525), Expect = 0.0 Identities = 485/485 (100%), Positives = 485/485 (100%) Query: 1 MAAELYAPASAAAADLANSNAGAAVGRKAGPRSPPSAPAPAPPPPAPAPPTLGNNHQESP 60 MAAELYAPASAAAADLANSNAGAAVGRKAGPRSPPSAPAPAPPPPAPAPPTLGNNHQESP Sbjct: 1 MAAELYAPASAAAADLANSNAGAAVGRKAGPRSPPSAPAPAPPPPAPAPPTLGNNHQESP 60 Query: 61 GWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDL 120 GWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDL Sbjct: 61 GWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDL 120 Query: 121 AEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLE 180 AEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLE Sbjct: 121 AEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLE 180 Query: 181 TSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREA 240 TSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREA Sbjct: 181 TSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREA 240 Query: 241 LNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQS 300 LNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQS Sbjct: 241 LNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQS 300 Query: 301 DILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSI 360 DILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSI Sbjct: 301 DILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSI 360 Query: 361 QFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFMSDGSSNTFPVWFEH 420 QFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFMSDGSSNTFPVWFEH Sbjct: 361 QFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFMSDGSSNTFPVWFEH 420 Query: 421 PVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGVQGGQIPE 480 PVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGVQGGQIPE Sbjct: 421 PVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGVQGGQIPE 480 Query: 481 LIFYA 485 LIFYA Sbjct: 481 LIFYA 485 >gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo sapiens] Length = 522 Score = 700 bits (1806), Expect = 0.0 Identities = 342/432 (79%), Positives = 375/432 (86%) Query: 54 NNHQESPGWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFY 113 NN +P W+ PT+RERNA+MFNN+LMADVHFVVGPPG T+ +P HKYVLAVGSSVF+ Sbjct: 91 NNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFH 150 Query: 114 AMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAK 173 AMFYG+LAE K EI IPDVEPAAFL +LKY+Y DEIDL ADTVLATLYAAKKYIVP LA+ Sbjct: 151 AMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLAR 210 Query: 174 ACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLE 233 ACVNFLETSL AKNACVLLSQS LFEEP+LTQRCWEVIDAQAE+AL+SEGFC+ID QTLE Sbjct: 211 ACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLE 270 Query: 234 IIVTREALNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEF 293 I+ RE LN KE VVFEA LNWAE EC+RQ L ++ NKR VLG+ALYL+RIPTM L++F Sbjct: 271 SILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDF 330 Query: 294 ANGAAQSDILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRY 353 ANGAAQS +LTL ET+ IFLWYTA KP L F RKGL PQRCHRFQS AYRSNQWRY Sbjct: 331 ANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRY 390 Query: 354 RGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFMSDGSSNT 413 RGRCDSIQFAVD+RVFIAG GLYGSS G AEYS KIELKR GVVL QNL+K+ SDGSSNT Sbjct: 391 RGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNT 450 Query: 414 FPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGV 473 FPVWFE+PVQ+E DTFYTAS +LDG+ELSYFGQEGMTEVQCGKV QFQCSSDSTNGTGV Sbjct: 451 FPVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGV 510 Query: 474 QGGQIPELIFYA 485 QGGQIPELIFYA Sbjct: 511 QGGQIPELIFYA 522 >gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo sapiens] Length = 461 Score = 700 bits (1806), Expect = 0.0 Identities = 342/432 (79%), Positives = 375/432 (86%) Query: 54 NNHQESPGWRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFY 113 NN +P W+ PT+RERNA+MFNN+LMADVHFVVGPPG T+ +P HKYVLAVGSSVF+ Sbjct: 30 NNLIPAPNWQGLYPTIRERNAMMFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFH 89 Query: 114 AMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAK 173 AMFYG+LAE K EI IPDVEPAAFL +LKY+Y DEIDL ADTVLATLYAAKKYIVP LA+ Sbjct: 90 AMFYGELAEDKDEIRIPDVEPAAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLAR 149 Query: 174 ACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLE 233 ACVNFLETSL AKNACVLLSQS LFEEP+LTQRCWEVIDAQAE+AL+SEGFC+ID QTLE Sbjct: 150 ACVNFLETSLSAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLE 209 Query: 234 IIVTREALNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEF 293 I+ RE LN KE VVFEA LNWAE EC+RQ L ++ NKR VLG+ALYL+RIPTM L++F Sbjct: 210 SILRRETLNAKEIVVFEAALNWAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDF 269 Query: 294 ANGAAQSDILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRY 353 ANGAAQS +LTL ET+ IFLWYTA KP L F RKGL PQRCHRFQS AYRSNQWRY Sbjct: 270 ANGAAQSGVLTLNETNDIFLWYTAAKKPELQFVSKARKGLVPQRCHRFQSCAYRSNQWRY 329 Query: 354 RGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFMSDGSSNT 413 RGRCDSIQFAVD+RVFIAG GLYGSS G AEYS KIELKR GVVL QNL+K+ SDGSSNT Sbjct: 330 RGRCDSIQFAVDKRVFIAGFGLYGSSCGSAEYSAKIELKRQGVVLGQNLSKYFSDGSSNT 389 Query: 414 FPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGV 473 FPVWFE+PVQ+E DTFYTAS +LDG+ELSYFGQEGMTEVQCGKV QFQCSSDSTNGTGV Sbjct: 390 FPVWFEYPVQIEPDTFYTASVILDGNELSYFGQEGMTEVQCGKVTVQFQCSSDSTNGTGV 449 Query: 474 QGGQIPELIFYA 485 QGGQIPELIFYA Sbjct: 450 QGGQIPELIFYA 461 >gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens] Length = 525 Score = 405 bits (1040), Expect = e-113 Identities = 225/501 (44%), Positives = 308/501 (61%), Gaps = 28/501 (5%) Query: 8 PASAAAADLANSNAGAAVGRKAGPRSPPSAPAPAPPPPAPAPPTLGNNHQES---PG--- 61 P++ AAA A NA AA A + P PAPP P G E PG Sbjct: 28 PSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAA 87 Query: 62 --------WRCCRPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFY 113 W+ +PT++ER A +FNNE++ DVHF+VG +++ +PAH++VLAVGS+VF Sbjct: 88 LQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFD 147 Query: 114 AMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAK 173 AMF G +A +EI +PDVEPAAFL LLK++YSDE+ + +TV+ TLY AKKY VPAL Sbjct: 148 AMFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEA 207 Query: 174 ACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLE 233 CV FL+ +L A NA +LL+Q+RLF+EP+L C E ID A+ +EGF +ID TL Sbjct: 208 HCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLV 267 Query: 234 IIVTREALNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEF 293 ++ R+ L +E +F AV+ W+EAEC+RQ L +TP N+R VLG+AL L+R P MT+EEF Sbjct: 268 AVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEF 327 Query: 294 ANGAAQSDILTLEETHSIFLWYTATNKPRLDFPLTKRKGLAPQRC--HRFQSSAYRSNQW 351 A G AQS IL E S+FL +T KPR++F R L + C +RFQ ++W Sbjct: 328 AAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCLRGKECSINRFQQV---ESRW 384 Query: 352 RYRGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRL--GVVLAQNLTKFMSDG 409 Y G D I+F+V++R+F+ G GLYGS G +Y V I++ VL QN T F DG Sbjct: 385 GYSGTSDRIRFSVNKRIFVVGFGLYGSIHGPTDYQVNIQIIHTDSNTVLGQNDTGFSCDG 444 Query: 410 SSNTFPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEV------QCGKVAFQFQC 463 S++TF V F+ PV+V + YTA A L G + S++G +G+ +V K F F Sbjct: 445 SASTFRVMFKEPVEVLPNVNYTACATLKGPD-SHYGTKGLRKVTHESPTTGAKTCFTFCY 503 Query: 464 SSDSTNGTGVQGGQIPELIFY 484 ++ + NGT V+ GQIPE+IFY Sbjct: 504 AAGNNNGTSVEDGQIPEVIFY 524 >gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens] Length = 482 Score = 382 bits (981), Expect = e-106 Identities = 211/479 (44%), Positives = 296/479 (61%), Gaps = 21/479 (4%) Query: 23 AAVGRKAGPRSPPSAPAPAPPPPAPAP--PTLGNNHQESPGWRCCRPTLRERNALMFNNE 80 AA G +A PA PPPP+P+ P L + W+ + +L+ER A +FN+E Sbjct: 7 AAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSE 66 Query: 81 LMADVHFVVGP------PGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEP 134 L++DV FV+G G + +PAH++VLA GS+VF AMF G +A +EI +PDVEP Sbjct: 67 LLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEP 126 Query: 135 AAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQ 194 AAFL LL+++YSDE+ + +TV+ TLY AKKY VPAL CV FL L A NA +LL+Q Sbjct: 127 AAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQ 186 Query: 195 SRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLN 254 +RLF+EP+L C + ID A+ +EGF +ID TL ++ R+ L+ +E+ +F AV+ Sbjct: 187 ARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVR 246 Query: 255 WAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHSIFLW 314 WAEAEC+RQ LP+T NK+ VLG+AL L+R P MT+EEFA G AQS IL+ E ++FL Sbjct: 247 WAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLH 306 Query: 315 YTATNKPRLDFPLTKRKGLAPQRC--HRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFIAG 372 +T KPR+++ R L + C +RFQ ++W Y G D I+F V+RR+ I G Sbjct: 307 FTVNPKPRVEYIDRPRCCLRGKECCINRFQQV---ESRWGYSGTSDRIRFTVNRRISIVG 363 Query: 373 LGLYGSSSGKAEYSVKIEL--KRLGVVLAQNLTKFMSDGSSNTFPVWFEHPVQVEQDTFY 430 GLYGS G +Y V I++ L QN T F DG++NTF V F+ P+++ + Y Sbjct: 364 FGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCY 423 Query: 431 TASAVLDGSELSYFGQEGMTEV-----QCGKVAFQFQCSSDSTNGTGVQGGQIPELIFY 484 TA A L G + S++G +G+ +V K F F S + NGT ++ GQIPE+IFY Sbjct: 424 TACATLKGPD-SHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIFY 481 >gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens] Length = 385 Score = 291 bits (746), Expect = 7e-79 Identities = 158/349 (45%), Positives = 221/349 (63%), Gaps = 13/349 (3%) Query: 23 AAVGRKAGPRSPPSAPAPAPPPPAPAP--PTLGNNHQESPGWRCCRPTLRERNALMFNNE 80 AA G +A PA PPPP+P+ P L + W+ + +L+ER A +FN+E Sbjct: 7 AAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSE 66 Query: 81 LMADVHFVVGP------PGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEP 134 L++DV FV+G G + +PAH++VLA GS+VF AMF G +A +EI +PDVEP Sbjct: 67 LLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEP 126 Query: 135 AAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQ 194 AAFL LL+++YSDE+ + +TV+ TLY AKKY VPAL CV FL L A NA +LL+Q Sbjct: 127 AAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQ 186 Query: 195 SRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLN 254 +RLF+EP+L C + ID A+ +EGF +ID TL ++ R+ L+ +E+ +F AV+ Sbjct: 187 ARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVR 246 Query: 255 WAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHSIFLW 314 WAEAEC+RQ LP+T NK+ VLG+AL L+R P MT+EEFA G AQS IL+ E ++FL Sbjct: 247 WAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLH 306 Query: 315 YTATNKPRLDFPLTKRKGLAPQRC--HRFQSSAYRSNQWRYRGRCDSIQ 361 +T KPR+++ R L + C +RFQ ++W Y G D I+ Sbjct: 307 FTVNPKPRVEYIDRPRCCLRGKECCINRFQQV---ESRWGYSGTSDRIR 352 >gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens] Length = 612 Score = 103 bits (258), Expect = 3e-22 Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 21/241 (8%) Query: 69 LRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIH 128 L E + E DV FVV + PAH+ +LA F A+ YG + E + E Sbjct: 22 LSEHIGALLIGEEYGDVTFVV----EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77 Query: 129 IP--DVEPAAFLILLKYMYSDEIDL---EADTVLATLYAAKKYIVPALAKACVNFLETSL 183 IP D AF +LLKY+Y+ L + + +L L A KY P L + +L T L Sbjct: 78 IPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTIL 137 Query: 184 EAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNT 243 +N C+ + L+ P+LT C +D A+ L SEGF + + L IV R++ Sbjct: 138 NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA 197 Query: 244 KEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDIL 303 E +F A+LNW CK N + + VR+P M+L E N S +L Sbjct: 198 PEKDIFLALLNW----CK--------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLL 245 Query: 304 T 304 + Sbjct: 246 S 246 >gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens] Length = 612 Score = 103 bits (258), Expect = 3e-22 Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 21/241 (8%) Query: 69 LRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIH 128 L E + E DV FVV + PAH+ +LA F A+ YG + E + E Sbjct: 22 LSEHIGALLIGEEYGDVTFVV----EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE 77 Query: 129 IP--DVEPAAFLILLKYMYSDEIDL---EADTVLATLYAAKKYIVPALAKACVNFLETSL 183 IP D AF +LLKY+Y+ L + + +L L A KY P L + +L T L Sbjct: 78 IPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTIL 137 Query: 184 EAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNT 243 +N C+ + L+ P+LT C +D A+ L SEGF + + L IV R++ Sbjct: 138 NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA 197 Query: 244 KEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDIL 303 E +F A+LNW CK N + + VR+P M+L E N S +L Sbjct: 198 PEKDIFLALLNW----CK--------HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLL 245 Query: 304 T 304 + Sbjct: 246 S 246 >gi|42741669 kelch repeat and BTB (POZ) domain containing 10 [Homo sapiens] Length = 606 Score = 87.4 bits (215), Expect = 3e-17 Identities = 54/210 (25%), Positives = 98/210 (46%), Gaps = 11/210 (5%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAEVKS-EIHIPDVEPAAFLILLKYMYSDEIDLEAD 154 +++P H+ +L+ S F F ++ E K E+ + +V+PA +++KY+YS IDL Sbjct: 42 KSLPCHRLILSACSPYFREYFLSEIDEAKKKEVVLDNVDPAILDLIIKYLYSASIDLNDG 101 Query: 155 TVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQ 214 V A ++ +P++ CV++L+ L N +L L + P L E + + Sbjct: 102 NVQDIFALASRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDR 161 Query: 215 AEMALRSEGFCEIDRQTLEIIVTREALNT-KEAVVFEAVLNWAEAECKRQGLPITPRNKR 273 + E F ++ Q L +++ ++LN KE VFEAV+ W + N+ Sbjct: 162 FVQICKEEDFMQLSPQELISVISNDSLNVEKEEAVFEAVMKWVRTD---------KENRV 212 Query: 274 HVLGRALYLVRIPTMTLEEFANGAAQSDIL 303 L +R MT + F + + DI+ Sbjct: 213 KNLSEVFDCIRFRLMTEKYFKDHVEKDDII 242 >gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens] Length = 544 Score = 83.6 bits (205), Expect = 4e-16 Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 15/187 (8%) Query: 121 AEVKSEIHIPDVEPAAFLILLKYMYSDEIDL---EADTVLATLYAAKKYIVPALAKACVN 177 ++ ++EI + D AF +LLKY+Y+ L + + +L L A KY P L + Sbjct: 4 SQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSE 63 Query: 178 FLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVT 237 +L T L +N C+ + L+ P+LT C +D A+ L SEGF + + L IV Sbjct: 64 YLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVL 123 Query: 238 REALNTKEAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGA 297 R++ E +F A+LNW CK N + + VR+P M+L E N Sbjct: 124 RDSFAAPEKDIFLALLNW----CK--------HNSKENHAEIMQAVRLPLMSLTELLNVV 171 Query: 298 AQSDILT 304 S +L+ Sbjct: 172 RPSGLLS 178 >gi|211904190 hypothetical protein LOC149478 [Homo sapiens] Length = 291 Score = 82.4 bits (202), Expect = 8e-16 Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 12/277 (4%) Query: 76 MFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAE-VKSEIHIPDVEP 134 + NN +DV FVVG + V AH+ +LA + F + + V S + + V Sbjct: 22 LVNNPRYSDVCFVVGQE--RQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPT 79 Query: 135 AAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQ 194 AFL +L+++Y++ + L +VL L AA +Y + L + C+ F+ L+ C L Sbjct: 80 EAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQV 139 Query: 195 SRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLN 254 + F +L +RC I+A ++ ALR+ GF E+ L ++ + L EA + A + Sbjct: 140 AVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARS 199 Query: 255 WAEAECKRQGLPITPRNKRHVLG---RALYLVRIPTMTLEEFANGAAQSDILTLEETHSI 311 WA R G + R V + L L + L Q ++ +E+ Sbjct: 200 WA-----RVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQIVEA 254 Query: 312 FLWYTATNKPRL-DFPLTKRKGLAPQRCHRFQSSAYR 347 + + P +R+G P+ HRF +++ Sbjct: 255 WKCHALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291 >gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo sapiens] Length = 621 Score = 80.1 bits (196), Expect = 4e-15 Identities = 54/174 (31%), Positives = 82/174 (47%), Gaps = 7/174 (4%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADT 155 R P H+ VLA S F A F + E E+H+ +V P +L Y+Y+ EI L+ + Sbjct: 42 REFPCHRLVLAACSPYFRARFLAE-PERAGELHLEEVSPDVVAQVLHYLYTSEIALDEAS 100 Query: 156 VLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQA 215 V AA ++ +P++ CV+FL+ L N + L + L + I A Sbjct: 101 VQDLFAAAHRFQIPSIFTICVSFLQKRLCLSNCLAVFRLGLLLDCARLAVAARDFICAHF 160 Query: 216 EMALRSEGFCEIDRQTLEIIVTREALNT-KEAVVFEAVLNW-----AEAECKRQ 263 + R F + L I++ + LN KE VFEAV+ W AEA+ +RQ Sbjct: 161 TLVARDADFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWAGSGDAEAQAERQ 214 >gi|148664209 kelch-like 10 [Homo sapiens] Length = 608 Score = 79.0 bits (193), Expect = 9e-15 Identities = 55/205 (26%), Positives = 96/205 (46%), Gaps = 12/205 (5%) Query: 100 AHKYVLAVGSSVFYAMFYGDLAEVKSEIH-IPDVEPAAFLILLKYMYSDEIDLEADTVLA 158 AHK +L SS F A+F + +++ IP + P ++++Y Y+ + + D V Sbjct: 52 AHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEK 111 Query: 159 TLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWE-VIDAQAEM 217 L AA ++ + + + C FL++ L N + + + PEL Q+ + ++ EM Sbjct: 112 LLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEM 171 Query: 218 ALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPITPRNKRHVL 276 S F E+ L+ I+ ++ LN K E VFEA+L W + P+N++ + Sbjct: 172 VKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHD---------PQNRKQHI 222 Query: 277 GRALYLVRIPTMTLEEFANGAAQSD 301 L VR+ M E F N +D Sbjct: 223 SILLPKVRLALMHAEYFMNNVKMND 247 >gi|170784846 kelch-like 7 isoform 1 [Homo sapiens] Length = 586 Score = 76.6 bits (187), Expect = 5e-14 Identities = 69/300 (23%), Positives = 127/300 (42%), Gaps = 33/300 (11%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAEVKS-EIHIPDVEPAAFLILLKYMYSDEIDLEAD 154 R +PAH+ VLA S F MF ++ E KS E+ + D EP L+++ Y+ I + ++ Sbjct: 53 RKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSN 112 Query: 155 TVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQ 214 V + L AA +Y + + K CV+FL+ ++A N + + + PEL + I Sbjct: 113 NVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQH 172 Query: 215 AEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPITPRNKR 273 +++ F ++D + + ++ ++ L + E V++A + W L N++ Sbjct: 173 FTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRW---------LKYDEPNRQ 223 Query: 274 HVLGRALYLVRIPTMTLEEFANGAAQSDILTLE-------------------ETHSIFLW 314 + L VR P ++ + F + Q++ L + E + Sbjct: 224 PFMVDILAKVRFPLIS-KNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVD 282 Query: 315 YTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWR--YRGRCDSIQFAVDRRVFIAG 372 T + + D+ + G PQ C F Y R + R D+ D V+I G Sbjct: 283 GTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILG 342 >gi|170784844 kelch-like 7 isoform 2 [Homo sapiens] Length = 564 Score = 76.6 bits (187), Expect = 5e-14 Identities = 69/300 (23%), Positives = 127/300 (42%), Gaps = 33/300 (11%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAEVKS-EIHIPDVEPAAFLILLKYMYSDEIDLEAD 154 R +PAH+ VLA S F MF ++ E KS E+ + D EP L+++ Y+ I + ++ Sbjct: 31 RKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSN 90 Query: 155 TVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQ 214 V + L AA +Y + + K CV+FL+ ++A N + + + PEL + I Sbjct: 91 NVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQH 150 Query: 215 AEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPITPRNKR 273 +++ F ++D + + ++ ++ L + E V++A + W L N++ Sbjct: 151 FTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRW---------LKYDEPNRQ 201 Query: 274 HVLGRALYLVRIPTMTLEEFANGAAQSDILTLE-------------------ETHSIFLW 314 + L VR P ++ + F + Q++ L + E + Sbjct: 202 PFMVDILAKVRFPLIS-KNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVD 260 Query: 315 YTATNKPRLDFPLTKRKGLAPQRCHRFQSSAYRSNQWR--YRGRCDSIQFAVDRRVFIAG 372 T + + D+ + G PQ C F Y R + R D+ D V+I G Sbjct: 261 GTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILG 320 >gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo sapiens] Length = 589 Score = 75.5 bits (184), Expect = 1e-13 Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 9/214 (4%) Query: 75 LMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVK-SEIHIPD-V 132 L+ L DV G RT P H+ VLA S F AMF G L E + SE++ + + Sbjct: 38 LLRQQRLFTDVLLHAG----NRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSI 93 Query: 133 EPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLL 192 P +LL Y YS + + + + L A + AC FLE +L N +L Sbjct: 94 HPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGML 153 Query: 193 SQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEA 251 S + +L + W + + + ++E F ++ + + +++ E L T+ E +V+E+ Sbjct: 154 LLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYES 213 Query: 252 VLNWAEAECKRQ--GLPITPRNKRHVLGRALYLV 283 +NW + K++ LP + R L A+YL+ Sbjct: 214 AINWISYDLKKRYCYLPELLQTVRLALLPAIYLM 247 >gi|45269145 kelch-like ECH-associated protein 1 [Homo sapiens] Length = 624 Score = 75.5 bits (184), Expect = 1e-13 Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%) Query: 100 AHKYVLAVGSSVFYAMFYGDLAEVKSEI-HIPDVEPAAFLILLKYMYSDEIDLEADTVLA 158 AHK VLA S VF AMF L E E+ I + P L+++ Y+ I + VL Sbjct: 95 AHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLH 154 Query: 159 TLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMA 218 + A Y + ++ +AC +FL L+ NA + + + EL QR E I Sbjct: 155 VMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEV 214 Query: 219 LRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQ 263 + E F + L +++R+ LN + E+ VF A +NW + +C+++ Sbjct: 215 AKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQR 260 >gi|22027642 kelch-like ECH-associated protein 1 [Homo sapiens] Length = 624 Score = 75.5 bits (184), Expect = 1e-13 Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%) Query: 100 AHKYVLAVGSSVFYAMFYGDLAEVKSEI-HIPDVEPAAFLILLKYMYSDEIDLEADTVLA 158 AHK VLA S VF AMF L E E+ I + P L+++ Y+ I + VL Sbjct: 95 AHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLH 154 Query: 159 TLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMA 218 + A Y + ++ +AC +FL L+ NA + + + EL QR E I Sbjct: 155 VMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEV 214 Query: 219 LRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQ 263 + E F + L +++R+ LN + E+ VF A +NW + +C+++ Sbjct: 215 AKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQR 260 >gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Homo sapiens] Length = 623 Score = 75.1 bits (183), Expect = 1e-13 Identities = 55/192 (28%), Positives = 89/192 (46%), Gaps = 6/192 (3%) Query: 68 TLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVK-SE 126 +L E+ L + +L D+ +V P HK VLA SS F AMF L+E K + Sbjct: 16 SLLEQLKLFYEQQLFTDIVLIV----EGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTH 71 Query: 127 IHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAK 186 +H+ +V+ A I++ Y Y+ + + TV A V + + C +L + A+ Sbjct: 72 VHLRNVDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAE 131 Query: 187 NACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNT-KE 245 N LLS + LF EL Q +++ + + F ++ L I++ + LN KE Sbjct: 132 NCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQDAFMQLSHDLLIDILSSDNLNVEKE 191 Query: 246 AVVFEAVLNWAE 257 V EA + W E Sbjct: 192 ETVREAAMLWLE 203 >gi|40807500 kelch-like 20 [Homo sapiens] Length = 609 Score = 75.1 bits (183), Expect = 1e-13 Identities = 77/282 (27%), Positives = 127/282 (45%), Gaps = 26/282 (9%) Query: 66 RPTLRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVK- 124 R TL N L + EL DV VVG + + AH+ +L+ S F AMF G+LAE + Sbjct: 52 RQTLEVINLLRKHREL-CDVVLVVG----AKKIYAHRVILSACSPYFRAMFTGELAESRQ 106 Query: 125 SEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLE 184 +E+ I D++ A +L+ + Y+ +I +E V L AA + + +AC FL+ L+ Sbjct: 107 TEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLD 166 Query: 185 AKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTK 244 N + + + EL + + + + SE F + L I++ + LN + Sbjct: 167 PSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVR 226 Query: 245 -EAVVFEAVLNWAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDIL 303 E VF AV+ W + + + +R L + L VR+P ++ +F G SD L Sbjct: 227 SEEQVFNAVMAWVK---------YSIQERRPQLPQVLQHVRLPLLS-PKFLVGTVGSDPL 276 Query: 304 TLEETHSIFLWYTATN-------KPRLDFPLTKRKGLAPQRC 338 + L A N +P + P T+ + P RC Sbjct: 277 IKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPR--KPIRC 316 >gi|128485503 kelch-like 30 [Homo sapiens] Length = 560 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 12/179 (6%) Query: 82 MADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAE-VKSEIHIPDVEPAAFLIL 140 +ADV +VG R +P H+ +LA+ S F+AMF GD AE + + + DVEPA L Sbjct: 14 LADVTLLVGG----RELPCHRGLLALSSPYFHAMFAGDFAESFSARVELRDVEPAVVGQL 69 Query: 141 LKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNA---CVLLSQSRL 197 + ++Y+ + + V A A + P++ K C +L+ L+A N C Q L Sbjct: 70 VDFVYTGRLTITQGNVEALTRTAARLHFPSVQKVCGRYLQQQLDAANCLGICEFGEQQGL 129 Query: 198 FEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNW 255 + + W + E R + F ++ R+ L + + L + E EA++ W Sbjct: 130 L---GVAAKAWAFLRENFEAVAREDEFLQLPRERLVTCLAGDLLQVQPEQSRLEALMRW 185 >gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens] Length = 571 Score = 70.9 bits (172), Expect = 3e-12 Identities = 53/196 (27%), Positives = 95/196 (48%), Gaps = 11/196 (5%) Query: 98 VPAHKYVLAVGSSVFYAMFYGDLAEVK-SEIHIPDVEPAAFLILLKYMYSDEIDLEADTV 156 + AHK VLA S F AMF G+L+E + SE+ ++ A +++Y Y+ + + DTV Sbjct: 46 IHAHKVVLASVSPYFKAMFTGNLSEKENSEVEFQCIDETALQAIVEYAYTGTVFISQDTV 105 Query: 157 LATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAE 216 + L AA + + K C FLE+ L+ N + + + +L + I E Sbjct: 106 ESLLPAANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCRDLYLAATKYICQNFE 165 Query: 217 MALRSEGFCEIDRQTLEIIVTREALN-TKEAVVFEAVLNWAEAECKRQGLPITPRNKRHV 275 ++E F E+ L+ IV+ + LN E VF A+ +W + + + ++ Sbjct: 166 AVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDV---------QERQKY 216 Query: 276 LGRALYLVRIPTMTLE 291 L + L VR+P ++++ Sbjct: 217 LAQLLNSVRLPLLSVK 232 >gi|38194229 kelch-like 17 [Homo sapiens] Length = 642 Score = 69.7 bits (169), Expect = 6e-12 Identities = 75/310 (24%), Positives = 130/310 (41%), Gaps = 51/310 (16%) Query: 26 GRKAGPRSPPSAPAP-APPPPAPAPPTLGNNHQESPGWRCCRPTL----------RERNA 74 GR P P P APPPP P PP E R RP RE ++ Sbjct: 10 GRTQSPEHGSPGPGPEAPPPPPPQPPA---PEAERTRPRQARPAAPMEGAVQLLSREGHS 66 Query: 75 LMFNNE-----------------LMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFY 117 + N++ L+ D+ V A + + AHK VLA S F+AMF Sbjct: 67 VAHNSKRHYHDAFVAMSRMRQRGLLCDIVLHV----AAKEIRAHKVVLASCSPYFHAMFT 122 Query: 118 GDLAEVK-SEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACV 176 +++E + + + + D++P A L+++ Y+ EI + V L AA + + AC Sbjct: 123 NEMSESRQTHVTLHDIDPQALDQLVQFAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACC 182 Query: 177 NFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIV 236 FL + L+ N + + +L + + ++E F + + + +V Sbjct: 183 KFLLSQLDPSNCLGIRGFADAHSCSDLLKAAHRYVLQHFVDVAKTEEFMLLPLKQVLELV 242 Query: 237 TREALNT-KEAVVFEAVLNWA--EAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEF 293 + ++LN E V+ AVL+W + + +RQ +P R + VR+P ++ +F Sbjct: 243 SSDSLNVPSEEEVYRAVLSWVKHDVDARRQHVP-----------RLMKCVRLPLLS-RDF 290 Query: 294 ANGAAQSDIL 303 G ++ L Sbjct: 291 LLGHVDAESL 300 >gi|194097389 kelch-like 38 [Homo sapiens] Length = 581 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/188 (26%), Positives = 85/188 (45%), Gaps = 6/188 (3%) Query: 69 LRERNALMFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEV-KSEI 127 LR+ N+L + ++ DV G R +P H+ VLA S F AMF E ++++ Sbjct: 21 LRQLNSLR-QSRILTDVSICAG----AREIPCHRNVLASSSPYFRAMFCSSFREKSEAKV 75 Query: 128 HIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKN 187 + ++P ++ Y+Y+ E + D VL + AA P L +AC ++L++ L N Sbjct: 76 QLKGIDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSN 135 Query: 188 ACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAV 247 ++ S + L ++ EV S E+ L + + L +E Sbjct: 136 CLGMIRLSEILSCETLKKKAREVALTSFPEVAASADLKELCALELRDYLGDDGLCGEEEK 195 Query: 248 VFEAVLNW 255 VFEA++ W Sbjct: 196 VFEALMVW 203 >gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] Length = 589 Score = 67.8 bits (164), Expect = 2e-11 Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 13/208 (6%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAEVKSE-IHIPD-VEPAAFLILLKYMYSDEIDLEA 153 R P H+ VLA S F AMF L E + + ++ D + P +LL + YS I + Sbjct: 55 RAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINE 114 Query: 154 DTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDA 213 + + L A + A FLE +L N ++ S + L + W + Sbjct: 115 ENAESLLEAGDMLQFHDVRDAAAEFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLV 174 Query: 214 QAEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQGLPITPRNK 272 E +SE F + + TL +++ + L T+ E VVFEA+L W + + + PR K Sbjct: 175 HFETVRQSEDFNSLSKDTLLDLISSDELETEDERVVFEAILQWVKHD-------LEPR-K 226 Query: 273 RHV--LGRALYLVRIPTMTLEEFANGAA 298 H+ L R++ L +P+ L+E + A Sbjct: 227 VHLPELLRSVRLALLPSDCLQEAVSSEA 254 >gi|34101268 kelch-like 8 [Homo sapiens] Length = 620 Score = 67.0 bits (162), Expect = 4e-11 Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 25/270 (9%) Query: 77 FNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSE-IHIPDVEPA 135 + N + DV VG ++ + HK VLA F AMF ++AE K I I D + Sbjct: 61 YENGELCDVTLKVG----SKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGD 116 Query: 136 AFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQS 195 A L+K++YS + L D V LYAA V +A+AC +++ N + + + Sbjct: 117 AIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFA 176 Query: 196 RLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLN 254 +L + + E F + Q L +++ LN + E V+ A + Sbjct: 177 ESHNRIDLMDMADQYACDHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIK 236 Query: 255 WAEAECKRQGLPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDIL--------TLE 306 W L P++ L L VR+P + ++ A+ I+ L+ Sbjct: 237 W---------LLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLD 287 Query: 307 ETHSIFLWYTATNKPRLDFPL--TKRKGLA 334 E + L ++ P ++ + T RK A Sbjct: 288 EARNYHLHLSSRAVPDFEYSIRTTPRKHTA 317 >gi|126116565 MYC binding protein 2 [Homo sapiens] Length = 4640 Score = 66.6 bits (161), Expect = 5e-11 Identities = 49/158 (31%), Positives = 77/158 (48%), Gaps = 21/158 (13%) Query: 339 HRFQSSAYRSNQWRYRGRC-DSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGV- 396 +RF+S W Y ++I+F+ D + + GLGL+G G+ EY+ KI+L LG Sbjct: 1197 NRFES---HGGGWGYSAHSVEAIRFSADTDILLGGLGLFG---GRGEYTAKIKLFELGPD 1250 Query: 397 ---------VLAQNLTKFMSDGSSNTFPVWFEHPVQVEQDTFYTASAVLDG--SELSYFG 445 +LA+ + + + F+ PV ++ +Y A A + G S+ G Sbjct: 1251 GGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHG 1310 Query: 446 QEGMTEVQCGKVAFQFQCSSDSTNGTGVQGGQIPELIF 483 Q +T V FQF+ S S NGT V GQIP+L++ Sbjct: 1311 QASITTDD--GVVFQFKSSKKSNNGTDVNAGQIPQLLY 1346 Score = 43.9 bits (102), Expect = 3e-04 Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 16/144 (11%) Query: 355 GRCDSIQFAVDRR-VFIAGLGLYGSSSGKAEYSVKIELK------------RLGVVLAQN 401 G D+I F+VD+ + + G +YG G EY +++ + R + Sbjct: 1704 GSPDAICFSVDKPGIVVVGFSVYGGG-GIHEYELEVLVDDSEHAGDSTHSHRWTSLELVK 1762 Query: 402 LTKFMSDGSSNTFPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGK-VAFQ 460 T D S+ + + V ++++ Y GS + G GMT VQC V F Sbjct: 1763 GTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTAN-GDGGMTTVQCPDGVTFT 1821 Query: 461 FQCSSDSTNGTGVQGGQIPELIFY 484 F S S+NGT GQIP++++Y Sbjct: 1822 FSTCSLSSNGTNQTRGQIPQILYY 1845 >gi|166235129 kelch-like 3 [Homo sapiens] Length = 587 Score = 66.6 bits (161), Expect = 5e-11 Identities = 73/297 (24%), Positives = 126/297 (42%), Gaps = 32/297 (10%) Query: 98 VPAHKYVLAVGSSVFYAMFYGDLAEVKSE-IHIPDVEPAAFLILLKYMYSDEIDLEADTV 156 + AH+ VLA S F AMF GD++E K++ I I DV+ L+ Y+Y+ EI++ + V Sbjct: 61 IEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV 120 Query: 157 LATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAE 216 L AA + + + C +FL++ L N + + + + +L Q+ + Sbjct: 121 QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP 180 Query: 217 MALRSEGFCEIDRQTLEIIVTREALN-TKEAVVFEAVLNWAEAE-----------CKRQG 264 + E F + + +++ + L + E VFEAV++W E + Sbjct: 181 EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR 240 Query: 265 LPITPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHSIFLWYTATNKPRLD 324 LP+ PR+ L++ T ++F A + +L L++ L KPR Sbjct: 241 LPLLPRDYLVQTVEEEALIK-NNNTCKDFLIEAMKYHLLPLDQR---LLIKNPRTKPRTP 296 Query: 325 FPLTKRK----GLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRR-----VFIAG 372 L K G AP+ + + ++W D I RR VF+AG Sbjct: 297 VSLPKVMIVVGGQAPKAIRSVECYDFEEDRW------DQIAELPSRRCRAGVVFMAG 347 >gi|55925604 kelch-like 18 [Homo sapiens] Length = 574 Score = 65.5 bits (158), Expect = 1e-10 Identities = 59/195 (30%), Positives = 92/195 (47%), Gaps = 20/195 (10%) Query: 100 AHKYVLAVGSSVFYAMFYGDLAEVKS-EIHIPDVEPAAFLILLKYMYSDEIDLEADTVLA 158 AH+ VLA F+AMF D+ E K EI + ++P+A L+ + Y+ + ++ V + Sbjct: 51 AHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQS 110 Query: 159 TLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQ---- 214 L A + ++ AC FL L KN + R F E T C + DA Sbjct: 111 LLMGASFLQLQSIKDACCTFLRERLHPKNCLGV----RQFAE---TMMCAVLYDAANSFI 163 Query: 215 ----AEMALRSEGFCEIDRQTLEIIVTREALNTK-EAVVFEAVLNWAEAECKRQG--LPI 267 E+++ SE F + + + +V+R+ LN K E VFEA L W + +++G LP Sbjct: 164 HQHFVEVSM-SEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPE 222 Query: 268 TPRNKRHVLGRALYL 282 N R L R +L Sbjct: 223 LLSNIRLPLCRPQFL 237 >gi|227497736 T-cell activation kelch repeat protein [Homo sapiens] Length = 601 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/166 (25%), Positives = 79/166 (47%), Gaps = 2/166 (1%) Query: 96 RTVPAHKYVLAVGSSVFYAMFYGDLAE-VKSEIHIPDVEPAAFLILLKYMYSDEIDLEAD 154 +T H+ VLA S F +MF L E + E+ I VE + ++L Y Y+ + L Sbjct: 59 KTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIVGVEAESMDLVLNYAYTSRVILTEA 118 Query: 155 TVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQ 214 V A AA + +P++ C ++ + L+ +N+ + + + EL R E I + Sbjct: 119 NVQALFTAASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKK 178 Query: 215 AEMALRSEGFCEIDRQTLEIIVTREALNT-KEAVVFEAVLNWAEAE 259 + + F ++ + L I+ + LN +E V+E+++ W E E Sbjct: 179 FLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIIRWFEHE 224 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.133 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,130,232 Number of Sequences: 37866 Number of extensions: 955046 Number of successful extensions: 24707 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 460 Number of HSP's successfully gapped in prelim test: 326 Number of HSP's that attempted gapping in prelim test: 15825 Number of HSP's gapped (non-prelim): 6272 length of query: 485 length of database: 18,247,518 effective HSP length: 106 effective length of query: 379 effective length of database: 14,233,722 effective search space: 5394580638 effective search space used: 5394580638 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.