Guide to the Human Genome
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Search of human proteins with 22538811

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22538811 chemokine (C-C motif) ligand 28 precursor [Homo
sapiens]
         (127 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22538811 chemokine (C-C motif) ligand 28 precursor [Homo sapi...   268   8e-73
gi|5730035 small inducible cytokine A27 precursor [Homo sapiens]       65   1e-11
gi|22538796 small inducible cytokine A25 precursor [Homo sapiens]      42   2e-04
gi|194239688 chemokine (C-C motif) ligand 20 isoform 2 [Homo sap...    28   1.5  
gi|4759076 chemokine (C-C motif) ligand 20 isoform 1 [Homo sapiens]    28   1.5  
gi|36951034 G protein-coupled receptor 78 [Homo sapiens]               28   1.9  
gi|61966923 forkhead box B2 [Homo sapiens]                             28   1.9  
gi|39777606 Rho guanine nucleotide exchange factor 1 isoform 1 [...    28   2.5  
gi|39777604 Rho guanine nucleotide exchange factor 1 isoform 3 [...    28   2.5  
gi|15011972 Rho guanine nucleotide exchange factor 1 isoform 2 [...    28   2.5  
gi|4505187 small inducible cytokine B9 precursor [Homo sapiens]        27   3.2  
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi...    27   3.2  
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi...    27   3.2  
gi|62122917 filaggrin family member 2 [Homo sapiens]                   27   4.2  
gi|21314720 Smad nuclear interacting protein [Homo sapiens]            27   5.5  
gi|4502833 neuronal nicotinic acetylcholine receptor beta 2 prec...    26   7.2  

>gi|22538811 chemokine (C-C motif) ligand 28 precursor [Homo
           sapiens]
          Length = 127

 Score =  268 bits (685), Expect = 8e-73
 Identities = 127/127 (100%), Positives = 127/127 (100%)

Query: 1   MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL 60
           MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL
Sbjct: 1   MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDL 60

Query: 61  AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET 120
           AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET
Sbjct: 61  AAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHET 120

Query: 121 YGHKTPY 127
           YGHKTPY
Sbjct: 121 YGHKTPY 127


>gi|5730035 small inducible cytokine A27 precursor [Homo sapiens]
          Length = 112

 Score = 65.5 bits (158), Expect = 1e-11
 Identities = 29/73 (39%), Positives = 47/73 (64%), Gaps = 1/73 (1%)

Query: 23 ILPIASSCCTEVSHH-ISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTV 81
          +LP +++CCT++    +S +LL +V    +Q ADGDC L A +LH+ +R IC+ P N ++
Sbjct: 26 LLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSL 85

Query: 82 KQWMKVQAAKKNG 94
           QW + Q  K +G
Sbjct: 86 SQWFEHQERKLHG 98


>gi|22538796 small inducible cytokine A25 precursor [Homo sapiens]
          Length = 150

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 10/95 (10%)

Query: 26  IASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHV--KRRRICVSPHNHTVKQ 83
           +   CC    + I   +L R    RIQ   G C+L A I ++  + R++C +P +  V++
Sbjct: 26  VFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQR 85

Query: 84  WMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKH 118
            MK+  A+     N    K HH   N+     G H
Sbjct: 86  AMKLLDAR-----NKVFAKLHH---NTQTFQAGPH 112


>gi|194239688 chemokine (C-C motif) ligand 20 isoform 2 [Homo
          sapiens]
          Length = 95

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 13/41 (31%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 52 QRADGDCDLAAVILHVKRR-RICVSPHNHTVKQWMKVQAAK 91
          Q A+  CD+ A+I H K++  +C +P    VK  +++ + K
Sbjct: 51 QLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKK 91


>gi|4759076 chemokine (C-C motif) ligand 20 isoform 1 [Homo
          sapiens]
          Length = 96

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 13/41 (31%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 52 QRADGDCDLAAVILHVKRR-RICVSPHNHTVKQWMKVQAAK 91
          Q A+  CD+ A+I H K++  +C +P    VK  +++ + K
Sbjct: 52 QLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKK 92


>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
          Length = 363

 Score = 28.1 bits (61), Expect = 1.9
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 12  AVCAALHASEAILPIASSCCTEVS-HHISRRLLERVN 47
           A  A LHA   +LP+A  C T +  H ++RR  +R++
Sbjct: 171 AFTATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMD 207


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 28.1 bits (61), Expect = 1.9
 Identities = 15/59 (25%), Positives = 23/59 (38%)

Query: 68  KRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTP 126
           +R+R  V   +HT       ++A   G G   H   HH   + +  H   H  + H  P
Sbjct: 105 RRKRFKVLRADHTHLHAGSTKSAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPP 163


>gi|39777606 Rho guanine nucleotide exchange factor 1 isoform 1
           [Homo sapiens]
          Length = 927

 Score = 27.7 bits (60), Expect = 2.5
 Identities = 9/36 (25%), Positives = 22/36 (61%)

Query: 26  IASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLA 61
           +A+ CC E+ HH+++ + +  ++ R++      DL+
Sbjct: 605 LAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLS 640


>gi|39777604 Rho guanine nucleotide exchange factor 1 isoform 3
           [Homo sapiens]
          Length = 879

 Score = 27.7 bits (60), Expect = 2.5
 Identities = 9/36 (25%), Positives = 22/36 (61%)

Query: 26  IASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLA 61
           +A+ CC E+ HH+++ + +  ++ R++      DL+
Sbjct: 557 LAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLS 592


>gi|15011972 Rho guanine nucleotide exchange factor 1 isoform 2
           [Homo sapiens]
          Length = 912

 Score = 27.7 bits (60), Expect = 2.5
 Identities = 9/36 (25%), Positives = 22/36 (61%)

Query: 26  IASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLA 61
           +A+ CC E+ HH+++ + +  ++ R++      DL+
Sbjct: 590 LAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLS 625


>gi|4505187 small inducible cytokine B9 precursor [Homo sapiens]
          Length = 125

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 58  CDLAAVILHVKRR-RICVSPHNHTVKQ----WMKVQAAKKNGKGNVCHRKKHHGK-RNSN 111
           C+   +I  +K   + C++P +  VK+    W K  + KK  K    H+KK   K R S 
Sbjct: 58  CEKIEIIATLKNGVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQ 117

Query: 112 RAHQGK 117
           R+ Q K
Sbjct: 118 RSRQKK 123


>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
          sapiens]
          Length = 847

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 12/60 (20%)

Query: 12 AVCAALHASEAILPIASSCCTEVSHHI-----SRRLLERVNMCRIQRADGDCDLAAVILH 66
          A+C  L  + AIL  AS  C  V+ H+     + +L+ RVN+        +C  AA ++H
Sbjct: 13 ALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNL-------KECFTAANLIH 65


>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
          sapiens]
          Length = 901

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 12/60 (20%)

Query: 12 AVCAALHASEAILPIASSCCTEVSHHI-----SRRLLERVNMCRIQRADGDCDLAAVILH 66
          A+C  L  + AIL  AS  C  V+ H+     + +L+ RVN+        +C  AA ++H
Sbjct: 13 ALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNL-------KECFTAANLIH 65


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 26.9 bits (58), Expect = 4.2
 Identities = 12/46 (26%), Positives = 22/46 (47%), Gaps = 7/46 (15%)

Query: 82  KQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY 127
           K++ K   +KK       HR+ H  +   +   + + +T GHK+ Y
Sbjct: 91  KEYCKASGSKK-------HRRGHRHQEEESETEEDEEDTPGHKSGY 129


>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
          Length = 396

 Score = 26.6 bits (57), Expect = 5.5
 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 10/61 (16%)

Query: 68  KRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHR----KKHHGKRNSNRAHQGKHETYGH 123
           KR R   SPH+ TVK   + +   + G+ +  HR    ++H   RNS+R    +H  + H
Sbjct: 95  KRNR---SPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDR---DRHRGHSH 148

Query: 124 K 124
           +
Sbjct: 149 Q 149


>gi|4502833 neuronal nicotinic acetylcholine receptor beta 2
           precursor [Homo sapiens]
          Length = 502

 Score = 26.2 bits (56), Expect = 7.2
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 4/59 (6%)

Query: 64  ILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYG 122
           +L+V  R    SP  HT+  W+KV   +K        + +HH  R   R  + + E  G
Sbjct: 318 VLNVHHR----SPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREG 372


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.131    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,087,085
Number of Sequences: 37866
Number of extensions: 202118
Number of successful extensions: 632
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 621
Number of HSP's gapped (non-prelim): 18
length of query: 127
length of database: 18,247,518
effective HSP length: 90
effective length of query: 37
effective length of database: 14,839,578
effective search space: 549064386
effective search space used: 549064386
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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