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Search of human proteins with 224831239
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224831239 integrin alpha M isoform 1 precursor [Homo
sapiens]
(1153 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 2298 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 2292 0.0
gi|34452173 integrin alpha X precursor [Homo sapiens] 1356 0.0
gi|62548866 integrin, alpha D precursor [Homo sapiens] 1325 0.0
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 576 e-164
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 472 e-132
gi|148728188 integrin, alpha E precursor [Homo sapiens] 416 e-116
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 406 e-113
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 395 e-109
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 384 e-106
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 380 e-105
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 375 e-103
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 212 1e-54
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 209 9e-54
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 167 5e-41
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 167 7e-41
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 167 7e-41
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 167 7e-41
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 164 4e-40
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 163 1e-39
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 157 7e-38
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 154 5e-37
gi|49170034 integrin, alpha 8 [Homo sapiens] 153 1e-36
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 149 1e-35
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 138 3e-32
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 132 2e-30
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 132 2e-30
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 94 1e-18
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 91 6e-18
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 87 1e-16
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 2298 bits (5956), Expect = 0.0
Identities = 1153/1153 (100%), Positives = 1153/1153 (100%)
Query: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR
Sbjct: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
Query: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK
Sbjct: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
Query: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL
Sbjct: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
Query: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN
Sbjct: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
Query: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL
Sbjct: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
Query: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT
Sbjct: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
Query: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV
Sbjct: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
Query: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP
Sbjct: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
Query: 481 HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 540
HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA
Sbjct: 481 HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 540
Query: 541 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 600
IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV
Sbjct: 541 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 600
Query: 601 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 660
DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK
Sbjct: 601 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 660
Query: 661 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 720
STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP
Sbjct: 661 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 720
Query: 721 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 780
NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD
Sbjct: 721 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 780
Query: 781 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 840
LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS
Sbjct: 781 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 840
Query: 841 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 900
QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA
Sbjct: 841 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 900
Query: 901 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 960
NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN
Sbjct: 901 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 960
Query: 961 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1020
LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV
Sbjct: 961 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1020
Query: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080
VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF
Sbjct: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080
Query: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140
TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD
Sbjct: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140
Query: 1141 MMSEGGPPGAEPQ 1153
MMSEGGPPGAEPQ
Sbjct: 1141 MMSEGGPPGAEPQ 1153
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 2292 bits (5939), Expect = 0.0
Identities = 1152/1153 (99%), Positives = 1152/1153 (99%), Gaps = 1/1153 (0%)
Query: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR
Sbjct: 1 MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQR 60
Query: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK
Sbjct: 61 GSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVK 120
Query: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL
Sbjct: 121 GLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL 180
Query: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN
Sbjct: 181 KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFN 240
Query: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL
Sbjct: 241 ITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQEL 300
Query: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT
Sbjct: 301 NTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
Query: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV
Sbjct: 361 SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLV 420
Query: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP
Sbjct: 421 LGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAP 480
Query: 481 HYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 540
HYYEQTRGGQVSVCPLPRG RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA
Sbjct: 481 HYYEQTRGGQVSVCPLPRG-RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVA 539
Query: 541 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 600
IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV
Sbjct: 540 IGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLV 599
Query: 601 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 660
DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK
Sbjct: 600 DLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQK 659
Query: 661 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 720
STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP
Sbjct: 660 STRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLP 719
Query: 721 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 780
NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD
Sbjct: 720 NCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDD 779
Query: 781 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 840
LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS
Sbjct: 780 LSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRS 839
Query: 841 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 900
QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA
Sbjct: 840 QRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKA 899
Query: 901 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 960
NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN
Sbjct: 900 NVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN 959
Query: 961 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1020
LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV
Sbjct: 960 LGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPV 1019
Query: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080
VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF
Sbjct: 1020 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1079
Query: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140
TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD
Sbjct: 1080 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1139
Query: 1141 MMSEGGPPGAEPQ 1153
MMSEGGPPGAEPQ
Sbjct: 1140 MMSEGGPPGAEPQ 1152
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 1356 bits (3510), Expect = 0.0
Identities = 702/1141 (61%), Positives = 840/1141 (73%), Gaps = 6/1141 (0%)
Query: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
+LL TAL GFNLDTE F+ ++ GFG SVVQ S VVVGAPQ+I AANQ G LY
Sbjct: 8 LLLFTALATSLGFNLDTEELTAFRVDSAGFGDSVVQYANSWVVVGAPQKITAANQTGGLY 67
Query: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
QC YSTG+CEPI LQVP EAVNMSLGLSLA+TTSP QLLACGPTVH C N Y+ GLCF
Sbjct: 68 QCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLTGLCF 127
Query: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
L G Q Q+ P + + CP+++ DI FLIDGSGSI +F M FV V+ Q ++
Sbjct: 128 LLGPT--QLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPS 185
Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
T FSLMQ+S +F+ HFTF+EF+ + NP SL+ + QL G T+TAT I+ VV LF+ + G
Sbjct: 186 TQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYG 245
Query: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
AR++A KIL+VITDG+K GD L Y+DVIP AD G+IRY IGVG AF++ S +ELN IA
Sbjct: 246 ARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIA 305
Query: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
SKP ++H+F+V +F+ALK IQNQL+EKIFAIEGT+T SSSSFE EM+QEGFSA T +GP
Sbjct: 306 SKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGP 365
Query: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
+L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQSLVLGAP
Sbjct: 366 VLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQSLVLGAP 425
Query: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDLVLIGAPHYYE
Sbjct: 426 RYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYE 485
Query: 485 QTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP 544
QTRGGQVSVCPLPRG R RW CDAVLYGEQG PWGRFGAALTVLGDVNGDKLTDV IGAP
Sbjct: 486 QTRGGQVSVCPLPRGWR-RWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAP 544
Query: 545 GEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTV 604
GEE+NRGAVYLFHG G ISPSHSQRIAGS+LS RLQYFGQ+LSGGQDLT DGLVDL V
Sbjct: 545 GEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAV 604
Query: 605 GAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRD 664
GA+G VLLLR++PVL V M+F P E+ R+ FEC +QVV + + +CL++ K +++
Sbjct: 605 GARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKN 664
Query: 665 RLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE 724
L +QS VT DLALD GR RA F ETKN + + +VLGL CE L LP+C+E
Sbjct: 665 LLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVE 724
Query: 725 DPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSIT 784
D V+PI LRLNF+LVG PL AF NLRP+LA DAQR FTA PFEKNCG D+ICQD+L I+
Sbjct: 725 DSVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGIS 784
Query: 785 FSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSW 844
FSF L L+VG E N V V NDGEDSY T +TF P LSYR V+ Q Q RS
Sbjct: 785 FSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSL 844
Query: 845 RLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS 904
L C+SA S STSC INH IF +++TF TFDV KA LG++LLL ANV+S
Sbjct: 845 HLTCDSAPVG--SQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSS 902
Query: 905 ENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTAS-ENTSRVMQHQYQVSNLGQ 963
ENN PRT+KT FQLELPVKYAVY VV+SH TKYLNF+ S E S V H+YQV+NLGQ
Sbjct: 903 ENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQ 962
Query: 964 RSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNC 1023
R LP+S+ F VPV LNQ +W +V+ +N S C +++ P SDFLA ++K PV++C
Sbjct: 963 RDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDC 1022
Query: 1024 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1083
SIA C R +CD+P F +QEE + TLKGNLSF W + + +VS AEI F+ SV++ L
Sbjct: 1023 SIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQL 1082
Query: 1084 PGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMS 1143
PGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLLLALITA LYK+GFFKRQYK+MM
Sbjct: 1083 PGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMME 1142
Query: 1144 E 1144
E
Sbjct: 1143 E 1143
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 1325 bits (3428), Expect = 0.0
Identities = 683/1141 (59%), Positives = 845/1141 (74%), Gaps = 9/1141 (0%)
Query: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
VLLL+ L HGFNLD E FQE+A GFGQSVVQ GSR+VVGAP E+VAANQ G LY
Sbjct: 6 VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQTGRLY 65
Query: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
C +TG C+PI L + EAVNMSLGL+LAA+T+ +LLACGPT+H+ C EN+Y KG C
Sbjct: 66 DCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCL 125
Query: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
L GS + Q P+A CP ++ DI FLIDGSGSI +DF +MK FV VM Q + +
Sbjct: 126 LLGSRW-EIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTD 184
Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
TLF+LMQYS +IHFTF +F+ +P+ +SLV PI QL G T TATGI VV +LF+ NG
Sbjct: 185 TLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNG 244
Query: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
ARK+A KIL+VITDG+K+ DPL Y DVIP+A++ G+IRY IGVG AF+ +RQELNTI+
Sbjct: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTIS 304
Query: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
S PP+DHVF+V+NF AL +IQ QL+EKI+A+EGTQ+ +SSSF+HEMSQEGFS A+T +G
Sbjct: 305 SAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGL 364
Query: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQ+LVLGAP
Sbjct: 365 FLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVLGAP 424
Query: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDL+LIGAPHYYE
Sbjct: 425 RYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYE 484
Query: 485 QTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP 544
QTRGGQVSVCPLPRG R +WQCDAVL GEQG PWGRFGAALTVLGDVN DKL DVAIGAP
Sbjct: 485 QTRGGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP 543
Query: 545 GEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTV 604
GE++NRGAVYLFHG S SGISPSHSQRIA S+LSPRLQYFGQ+LSGGQDLT DGL+DL V
Sbjct: 544 GEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAV 603
Query: 605 GAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRD 664
GA+G VLLLRS PVL+V M F+P EVA+ V+ C ++ EAG+ VCL +QKS+ D
Sbjct: 604 GARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLD 663
Query: 665 RLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE 724
+L G IQS V +DLALD GR SRA+FNETKN T + + LGL CETLKL LP+C+E
Sbjct: 664 QL--GDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVE 721
Query: 725 DPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSIT 784
D VSPI+L LNFSLV P+ + NLRPVLA +Q LFTA PFEKNCG D +C+ DL +T
Sbjct: 722 DVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVT 781
Query: 785 FSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSW 844
SF L L VG E NV VTV N GEDSY T V+ ++P LS+R+VS Q Q Q +
Sbjct: 782 LSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSAL 841
Query: 845 RLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS 904
RLACE+ TE G L+S+ CS+NHPIF E S TF +TFDV KA+LG+++L++A+ +S
Sbjct: 842 RLACETV-PTEDEG-LRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASS 899
Query: 905 ENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNF-TASENTSRVMQHQYQVSNLGQ 963
ENN ++K FQLELPVKYAVY +++ STKY NF T+ E + +H+Y+V+NL Q
Sbjct: 900 ENNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQ 959
Query: 964 RSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNC 1023
R L IS+ F VPV LN +WD S++L C ++ + P HSDFL ++ ++P+++C
Sbjct: 960 RDLAISINFWVPVLLNGVAVWDVVMEAPSQSL--PCVSERKPPQHSDFLTQISRSPMLDC 1017
Query: 1024 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1083
SIA C + +CD+P F +QEE + TLKGNLSF W +T +L+VS AEI F+ SV++ L
Sbjct: 1018 SIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQL 1077
Query: 1084 PGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMS 1143
PGQ AF+R+Q E +E EV N +P+I+GSSVG LLLLALITA LYKLGFFKR YK+M+
Sbjct: 1078 PGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLE 1137
Query: 1144 E 1144
+
Sbjct: 1138 D 1138
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 576 bits (1484), Expect = e-164
Identities = 395/1158 (34%), Positives = 603/1158 (52%), Gaps = 69/1158 (5%)
Query: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
Query: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQP 134
P+ L+ + LG++LA + +LAC P + +TC +NTY+ GLC+LF NL+
Sbjct: 82 PVTLRGS-NYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPM 140
Query: 135 QKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSE 194
+ + C + + D+ FL DGS S+ P +F+++ +F+ VM++L + F+ +Q+S
Sbjct: 141 LQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFST 200
Query: 195 EFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILV 254
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L+
Sbjct: 201 SYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLI 260
Query: 255 VITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQ 314
+ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V
Sbjct: 261 IITDGE--ATDSGNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKI 313
Query: 315 VNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDW 374
++ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DW
Sbjct: 314 LDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDW 373
Query: 375 AGGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLV 432
AGG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 374 AGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRV 433
Query: 433 AMFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQ 490
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+
Sbjct: 434 LLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGR 493
Query: 491 VSVCPLPRGQRARWQCDAV--LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEED 548
V + QR + + V L G+ G P GRFG A+T L D+NGD L DVA+GAP EE
Sbjct: 494 VFIY-----QRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE- 547
Query: 549 NRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG 608
+GAVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+
Sbjct: 548 -QGAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAES 605
Query: 609 HVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLR 667
+++L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS +
Sbjct: 606 QMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF- 663
Query: 668 EGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPV 727
+G++ + +TY L LD R R +F ++ RR V + +C P C++D +
Sbjct: 664 QGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLI 722
Query: 728 SPIVLRLNFSL---VGTPLS--AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLS 782
SPI + LNFSL GTP A G P + + T PFEKNCG D C+ +L
Sbjct: 723 SPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLR 782
Query: 783 ITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQR 842
++FS L + +V +++ N ED+Y Q+ FP LS+RKV L +
Sbjct: 783 VSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHS 839
Query: 843 SWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANV 902
++CE E ++ SC+++ PIF V + F+ +S G+ + L ANV
Sbjct: 840 QIPVSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANV 898
Query: 903 TSEN-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV--- 958
T N + +P+ Y + +++ ST Y++FT ++H YQV
Sbjct: 899 TCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQ 958
Query: 959 SNLGQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAEL 1015
++ ++P + V VP ++ I + V + ERLP ++ L
Sbjct: 959 PSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGAL 1018
Query: 1016 RKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILF 1075
+ PVV ++E + G L I+ S + + S+ I F
Sbjct: 1019 FRCPVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISF 1059
Query: 1076 NDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFK 1135
N S L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFK
Sbjct: 1060 NSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFK 1118
Query: 1136 RQYKDMMSEG-GPPGAEP 1152
R K+ M G G P P
Sbjct: 1119 RNLKEKMEAGRGVPNGIP 1136
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 472 bits (1214), Expect = e-132
Identities = 342/1036 (33%), Positives = 520/1036 (50%), Gaps = 68/1036 (6%)
Query: 143 GCPQEDSDIAFLID---GSGSIIPHDFR----RMKEFVSTVMEQLKKSKTLFSLMQYSEE 195
G P E + L G+G +P R K T+ LF+ +Q+S
Sbjct: 59 GAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTS 118
Query: 196 FRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVV 255
++ F F ++ +P +L+K + +L T+T I V E+F GAR +A K+L++
Sbjct: 119 YKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLII 178
Query: 256 ITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQV 315
ITDGE G D + +IRY+IG+G F++++S++ L+ ASKP + V +
Sbjct: 179 ITDGEATDS--GNIDAAKD-----IIRYIIGIGKHFQTKESQETLHKFASKPASEFVKIL 231
Query: 316 NNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWA 375
+ FE LK + +L++KI+ IEGT +SF E+S G SA ++ ++ VG+ DWA
Sbjct: 232 DTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWA 291
Query: 376 GGVF-LYTSKEKSTFINMTRVDSDMNDAYLGYAAA-IILRNRVQSLVLGAPRYQHIGLVA 433
GG L + TFI + ++ YLGY + R + L GAPRYQH+G V
Sbjct: 292 GGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVL 351
Query: 434 MFR--QNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQV 491
+F+ Q G W + GTQIG+YFG LC VDVD +G T+L+LIGAP +Y + RGG+V
Sbjct: 352 LFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRV 411
Query: 492 SVCPLPRGQRARWQCDAV--LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDN 549
+ QR + + V L G+ G P GRFG A+T L D+NGD L DVA+GAP EE
Sbjct: 412 FIY-----QRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEE-- 464
Query: 550 RGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH 609
+GAVY+F+G G G+SP SQRI G+++ +Q+FG+S+ G +DL DGL D+ VGA+
Sbjct: 465 QGAVYIFNGRHG-GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQ 523
Query: 610 VLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV-KGKEAGEVRVCLHVQKSTRDRLRE 668
+++L S+PV+ + +M F+P E+ + EC+ K KE + +C + KS + +
Sbjct: 524 MIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI-KSLIPQF-Q 581
Query: 669 GQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVS 728
G++ + +TY L LD R R +F ++ RR V + +C P C++D +S
Sbjct: 582 GRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVT-TSMSCTDFSFHFPVCVQDLIS 640
Query: 729 PIVLRLNFSL---VGTPL-SAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSIT 784
PI + LNFSL GTP G P + + T PFEKNCG D C+ +L ++
Sbjct: 641 PINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVS 700
Query: 785 FSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSW 844
FS L + +V +++ N ED+Y Q+ FP LS+RKV L +
Sbjct: 701 FSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEML---KPHSQI 757
Query: 845 RLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS 904
++CE E ++ SC+++ PIF V + F+ +S G+ + L ANVT
Sbjct: 758 PVSCEELPE-ESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816
Query: 905 EN-NMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQV---SN 960
N + +P+ Y + +++ ST Y++FT ++H YQV +
Sbjct: 817 NNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPS 876
Query: 961 LGQRSLP-ISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSD--FLAELRK 1017
+ ++P + V VP ++ I + V + ERLP ++ L +
Sbjct: 877 IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFR 936
Query: 1018 APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFND 1077
PVV ++E + G L I+ S + + S+ I FN
Sbjct: 937 CPVV------------------FRQEILVQVIGTLELVGEIEAS-SMFSLCSSLSISFNS 977
Query: 1078 SVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQ 1137
S L G A + +Q KV+ L L V S +GGLLLL LI LYK+GFFKR
Sbjct: 978 SKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRN 1036
Query: 1138 YKDMMSEG-GPPGAEP 1152
K+ M G G P P
Sbjct: 1037 LKEKMEAGRGVPNGIP 1052
Score = 58.2 bits (139), Expect = 5e-08
Identities = 132/529 (24%), Positives = 213/529 (40%), Gaps = 100/529 (18%)
Query: 17 FNLDTENAMTFQENARG--FGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCE 74
+NLD A +F G FG V+Q+ G+ V+VGAP E N GSLYQC TG C
Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV-GNGVIVGAPGE---GNSTGSLYQCQSGTGHCL 81
Query: 75 PIRLQVPVEAVNMSLGLSLAATTSPPQLLACG---PTVHQTCSE-NTYVKG--------- 121
P+ L+ + LG++LA + +L T ++T + + YVK
Sbjct: 82 PVTLR-GSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKH 140
Query: 122 ------LCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDG----SGSI---------- 161
L FG+ + F E L P + + DG SG+I
Sbjct: 141 VKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYI 200
Query: 162 --------------IPHDF--RRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEF 205
H F + EFV +++ +K K LF+ +Q + + I T K+
Sbjct: 201 IGIGKHFQTKESQETLHKFASKPASEFVK-ILDTFEKLKDLFTELQ-KKIYVIEGTSKQD 258
Query: 206 QNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDP 265
+ N I+ L R H G GA+ A L + D +
Sbjct: 259 LTSFNMELSSSGISADLSRGHAVVG-----------AVGAKDWAGGFLDLKADLQD-DTF 306
Query: 266 LGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPR-DHVFQVNNFEALKTI 324
+G E + PE R G + Y + SRQ+ + +AS PR H+ +V F+ +
Sbjct: 307 IGNEPLTPEV-RAGYLGYTV------TWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGG 359
Query: 325 QNQLREKIFAIEGTQTGSSSSFE---HEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLY 381
+ ++ I GTQ GS E ++ Q+G + + PL G VF+Y
Sbjct: 360 GHW--SQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFY---GEQRGGRVFIY 414
Query: 382 TSKEKSTFINMTRVDSDMNDAYLGYAAAI-----ILRNRVQSLVLGAPRYQHIGLVAMFR 436
++ F ++ + D + AI I + + + +GAP + G V +F
Sbjct: 415 QRRQLG-FEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAP-LEEQGAVYIFN 472
Query: 437 QNTG--MWESNANVKGTQIGA---YFGASLCSV-DVDSNGSTDLVLIGA 479
G + + ++GTQ+ + +FG S+ V D++ +G D V +GA
Sbjct: 473 GRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLAD-VAVGA 520
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 416 bits (1068), Expect = e-116
Identities = 306/1014 (30%), Positives = 505/1014 (49%), Gaps = 70/1014 (6%)
Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQ 206
++IA ++DGSGSI P DF+R K+F+S +M K + F+L+QY + F ++ Q
Sbjct: 201 TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260
Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
+ + V+ ITQ+ T TA+ ++ V+ +F ++G+R+ A K++VV+TDG F DPL
Sbjct: 261 DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 267 GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQN 326
VI +GV R+ IGVG+ F+S ++ +ELN IAS P H F+V N+ AL + +
Sbjct: 321 NLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLS 380
Query: 327 QLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP-LLSTVGSYDWAGGVFLY-TSK 384
+LR I ++EGT + ++++Q GFSA I LL VG++DW+GG LY T
Sbjct: 381 KLRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRS 437
Query: 385 EKSTFINMTRVDSDMNDA----YLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTG 440
+ F+N T + +A YLGYA A++ + S + GAPRY+H G V ++
Sbjct: 438 RRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGR 497
Query: 441 MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQ 500
++G Q+G+YFG+ LC VD+D +GSTD +L+ AP Y+ G+V V L Q
Sbjct: 498 EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSE-Q 556
Query: 501 RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP----GEEDNR--GAVY 554
+ +L G G RFG A+ +GD++ DKLTDVAIGAP G +D G+VY
Sbjct: 557 DGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVY 616
Query: 555 LFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLR 614
+++G G+S S SQRI S ++P LQYFG S++GG D++ DGL D+TVG G ++ R
Sbjct: 617 IYNG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFR 675
Query: 615 SQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSV 674
S+PV+R+K M F P + + VR+C + S G +++
Sbjct: 676 SRPVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEI-SSVTTASESGLREAL 724
Query: 675 VTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN----CIEDPVSPI 730
+ + L +D G+ R ++ ++ + +Q CE L L +P C ED S
Sbjct: 725 LNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNA 783
Query: 731 VLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSL 790
+++++ L TP + +P+L + P+EK C N C +L + + +S
Sbjct: 784 SVKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA-TTVSQ 841
Query: 791 DCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACES 850
LVVG +E + + + N GEDSY T + +P +L L+ + S + C+
Sbjct: 842 QELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQ------LKRMQKPPSPNIQCDD 895
Query: 851 ASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPR 910
++ +C I HP+ + S ++ + ++ A + VT+ N R
Sbjct: 896 PQPV---ASVLIMNCRIGHPVL-KRSSAHVSVVWQLEENAFPNRTADITVTVTNSNE--R 949
Query: 911 TNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISL 970
+ L ++ V++ S Y+N + S + + V L
Sbjct: 950 RSLANETHTLQFRHGFVAVLSK--PSIMYVN--TGQGLSHHKEFLFHVHGENLFGAEYQL 1005
Query: 971 VFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQR 1030
VP +L + ++T ++ + ++ER ++S + + + V+C IA
Sbjct: 1006 QICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSS-VQHVEEWHSVSCVIA---- 1060
Query: 1031 IQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFV 1090
++ N T+ +S+D + + + EI FN S++ L +
Sbjct: 1061 ----------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENH-- 1108
Query: 1091 RSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1144
R++ E + LP+I+ SVGGLL+L +I L+K GFFKR+Y+ + E
Sbjct: 1109 RTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLE 1162
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 406 bits (1043), Expect = e-113
Identities = 231/444 (52%), Positives = 279/444 (62%), Gaps = 53/444 (11%)
Query: 752 VLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDG 811
+LA DAQR FTA PFEKNCG D+ICQD+L I+FSF L L+VG E N V V NDG
Sbjct: 1 MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
Query: 812 EDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPI 871
EDSY T +TF P LSYR V+ Q Q RS L C+SA S STSC INH I
Sbjct: 61 EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVG--SQGTWSTSCRINHLI 118
Query: 872 FPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVT 931
F +++TF TFDV KA LG++LLL ANV+SENN PRT+KT FQLELPVKYAVY VV+
Sbjct: 119 FRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVS 178
Query: 932 SHGVSTKYLNFTAS-ENTSRVMQHQYQ-----------VSNLGQRSLPISLVFLVPVRLN 979
SH TKYLNF+ S E S V H+YQ V+NLGQR LP+S+ F VPV LN
Sbjct: 179 SHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELN 238
Query: 980 QTVIW-----DRPQV----------------------------------TFSENLSSTCH 1000
Q +W PQV F +N S C
Sbjct: 239 QEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCS 298
Query: 1001 TKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKT 1060
+++ P SDFLA ++K PV++CSIA C R +CD+P F +QEE + TLKGNLSF W +
Sbjct: 299 SEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI 358
Query: 1061 SHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLL 1120
+ +VS AEI F+ SV++ LPGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLL
Sbjct: 359 LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLL 418
Query: 1121 LALITAALYKLGFFKRQYKDMMSE 1144
LALITA LYK+GFFKRQYK+MM E
Sbjct: 419 LALITAVLYKVGFFKRQYKEMMEE 442
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 395 bits (1015), Expect = e-109
Identities = 345/1214 (28%), Positives = 554/1214 (45%), Gaps = 127/1214 (10%)
Query: 6 LLLTALTLCHGFNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRG 61
LL L C FN+D +N+MTF FG +V Q + G V++G+P N+ G
Sbjct: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77
Query: 62 SLYQCDYSTGSCEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQ 111
+Y+C G P ++L +PV NM+ G +L T LACGP
Sbjct: 78 DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAY 136
Query: 112 TCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKE 171
C Y G+C + P ++ C + DI ++DGS SI P D +
Sbjct: 137 RCGHLHYTTGICSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTA 191
Query: 172 FVSTVMEQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTA 228
F++ ++E++ +T ++QY E F ++ + K I Q GR T TA
Sbjct: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251
Query: 229 TGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVG 288
GI +E F GAR+ K++V++TDGE D + VI + + E + R+ I +
Sbjct: 252 LGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAIL 310
Query: 289 DAFR-----SEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
++ +EK +E+ +IAS+P H F V++ AL TI L E+IFA+E T S+
Sbjct: 311 GSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSA 370
Query: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSD 398
+SFE EMSQ GFSA + + +L VG+YDW G V + + + +TF + ++
Sbjct: 371 ASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE 430
Query: 399 MNDAYLGYAAAIILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYF 457
+YLGY + L + G PRY H G V ++R G + + G QIG+YF
Sbjct: 431 PLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYF 490
Query: 458 GASLCSVDVDSNGSTDLVLIGAPHY---------------YEQTR-GGQVSVCPLPRGQR 501
G+ L + D+D + +TD++L+GAP Y QTR Q+S+ P+ +
Sbjct: 491 GSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 550
Query: 502 ARWQCDAVLYGEQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 560
+ Q ++ + +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG S
Sbjct: 551 SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-S 609
Query: 561 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLR 620
G I ++QRI L++FGQS+ G DL DGL D+T+G G L S+ V
Sbjct: 610 GKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAV 669
Query: 621 VKAIMEFNPREVARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTY 677
VK M F P +V C+ ++GKE VC V+ KS D + E +Q Y
Sbjct: 670 VKVTMNFEPNKVNIQKKNCH---MEGKETVCINATVCFDVKLKSKEDTIYEADLQ----Y 722
Query: 678 DLALDSGRPHSRAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNF 736
+ LDS R SR+ F+ T + +R V T + + + +D V + L+F
Sbjct: 723 RVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDF 779
Query: 737 SLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG 796
+L PVL + PF K+CGN C DLS+ + D L+V
Sbjct: 780 NLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVR 833
Query: 797 GPRE-FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTE 855
+ FNV++TV+N + +Y T+ + +L + + +Q +CES
Sbjct: 834 SQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---- 881
Query: 856 VSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKT 914
+ +C + +P VTF I F ++ + N + L A SE +
Sbjct: 882 -----HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDN 936
Query: 915 EFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------L 961
+ +PVKY V + S S +++ A+E V+ + N
Sbjct: 937 VVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF 995
Query: 962 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFL 1012
L +S+ F V++ ++ SEN + H E ++ + +D
Sbjct: 996 PMPELKLSISFPNMTSNGYPVLYP-TGLSSSENANCRPHIFEDPFSINSGKKMTTSTD-- 1052
Query: 1013 AELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAE 1072
L++ +++C+ I C++ I + N +L L +IK+ + L + E
Sbjct: 1053 -HLKRGTILDCNTCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGE 1108
Query: 1073 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYK 1130
+ ++ L + + + ++ +P +PL I+ S+ GLLLL L+ AL+K
Sbjct: 1109 LRSENASLVL---SSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWK 1165
Query: 1131 LGFFKRQYKDMMSE 1144
+GFFKR K M +
Sbjct: 1166 IGFFKRPLKKKMEK 1179
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 384 bits (987), Expect = e-106
Identities = 346/1174 (29%), Positives = 553/1174 (47%), Gaps = 94/1174 (8%)
Query: 13 LCHGFNLDTENAMTFQENARG-FGQSVVQLQGSR---VVVGAPQEIVAANQRGSLYQC-- 66
LC FNLD + F FG SV+Q G ++VGAP + + ++RG +Y+C
Sbjct: 19 LCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPV 78
Query: 67 --------------DYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQT 112
DY G+ AVNM LG+SL T +AC P +
Sbjct: 79 GGAHNAPCAKGHLGDYQLGNSSH-------PAVNMHLGMSLLETDGDGGFMACAPLWSRA 131
Query: 113 CSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEF 172
C + + G+C ++ + Q P A R CP D+ ++DGS SI P + ++ F
Sbjct: 132 CGSSVFSSGICARVDASFQPQGSLAPTAQR-CPTY-MDVVIVLDGSNSIYP--WSEVQTF 187
Query: 173 VSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTAT 229
+ ++ +L + L+QY E ++ +F+ K +++ GR T TA
Sbjct: 188 LRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQ 247
Query: 230 GIRKVVRELFNITNGARKNAFKILVVITDGEKF-GDPLGYEDVIPEADREGVIRYVIGV- 287
I E F+ ++G R A ++LVV+TDGE G+ L EA R V RY I V
Sbjct: 248 AIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGR--VTRYGIAVL 305
Query: 288 GDAFRSEKSR----QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
G R ++ +E+ TIAS P F V + AL I + L ++IF +EG+ +
Sbjct: 306 GHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENE 365
Query: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDS-----D 398
SSF EMSQ GFS +G L VG+YDW G V + M D
Sbjct: 366 SSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQ 425
Query: 399 MNDAYLGYA-AAIILRNRVQSLVLGAPRYQHIGLVAMFR-QNTGMWESNANVKGTQIGAY 456
+ AYLGY+ ++++LR + + GAPR++H G V F+ + G +++G QIG+Y
Sbjct: 426 NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSY 485
Query: 457 FGASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGQRARWQCDAVLYGEQ 514
FG+ LC +D D +G+TD++L+ AP + + G+V V + GQ++ L E
Sbjct: 486 FGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLV--GQQSLLTLQGTLQPEP 543
Query: 515 GQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAG 574
Q RFG A+ L D+N D DVA+GAP E+ ++GA+YL+HGT SG+ P +QRIA
Sbjct: 544 PQD-ARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQ-SGVRPHPAQRIAA 601
Query: 575 SKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVAR 634
+ + L YFG+S+ G DL D LVD+ VGAQG +LL S+P++ + +E P+ ++
Sbjct: 602 ASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISV 661
Query: 635 NVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNE 694
+C +G+EA + L Q ++R R Q + + +LD +RA F+
Sbjct: 662 VQRDCRR---RGQEAVCLTAALCFQVTSRTPGRWDH-QFYMRFTASLDEWTAGARAAFDG 717
Query: 695 T--KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPV 752
+ + S RR +G TCE L + + D + P+ L + F+L T PV
Sbjct: 718 SGQRLSPRRLRLSVG-NVTCEQLHFHVLDT-SDYLRPVALTVTFALDNTTKPG-----PV 770
Query: 753 LAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSF-----MSLDCLVVGGPREFNVTVTV 807
L E + L PF K+CG DN C DL + + +V GG R+ V+ T+
Sbjct: 771 LNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTL 830
Query: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
N E++Y T ++ F +L +++L QR + ++ C + S+ + CS+
Sbjct: 831 ENRKENAYNTSLSLIFSRNLH---LASLTPQR-ESPIKVECAAPSA-------HARLCSV 879
Query: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS---ENNMPRTNKTEFQLELPVKY 924
HP+F ++VTF + F+ S +SL +++ +K +S E N + T Q ++Y
Sbjct: 880 GHPVFQTGAKVTFLLEFEF-SCSSLLSQVFVKLTASSDSLERNGTLQDNTA-QTSAYIQY 937
Query: 925 AVYMVVTSHGVSTKYLNF---TASENTSRVMQHQYQVSNLGQRSLP-ISLVFLVPVRLNQ 980
+++ +S +Y T + +V NLG + + + L+P +
Sbjct: 938 EPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHG 997
Query: 981 TVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGI 1040
+ + N S P EL+ +N S CQ ++C +
Sbjct: 998 GNYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAK 1057
Query: 1041 QEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEP 1100
E + L + +++ + L +VST E+ + L + S E V+
Sbjct: 1058 GTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEV-VQT 1116
Query: 1101 FEVPNPLPLIVGSSVGGLLLLALITAALYKLGFF 1134
+ L +++GS +GGLLLLAL+ L+KLGFF
Sbjct: 1117 RPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 380 bits (977), Expect = e-105
Identities = 340/1197 (28%), Positives = 541/1197 (45%), Gaps = 127/1197 (10%)
Query: 17 FNLDTENAMTFQENARGFGQSVVQ---LQGSR-VVVGAPQEIVAANQRGSLYQCDYSTGS 72
FN+DT + F VQ + G++ +VVGAP E + G +Y+C G+
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
Query: 73 CEPIRL------QVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLF 126
C + L V NM LGLSLA LAC P C + Y G+C
Sbjct: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
Query: 127 GSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQ--LKKSK 184
SN R P AL+ C Q DI ++DGS SI P + ++ F+ ++++ + +
Sbjct: 143 NSNFRFSKTVAP-ALQRC-QTYMDIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQ 198
Query: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLG-RTHTATGIRKVVRELFNITN 243
++QY E+ F ++++ + I Q G T TA GI E F
Sbjct: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256
Query: 244 GARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRS-----EKSRQ 298
G RK A K+++VITDGE P E VI +++R+ V RY + V + E
Sbjct: 257 GGRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLN 315
Query: 299 ELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAA 358
E+ IAS P H F V + ALK I + L ++IF++EGT + +SF EMSQ GFS+
Sbjct: 316 EIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNK-NETSFGLEMSQTGFSSH 374
Query: 359 ITSNGPLLSTVGSYDWAGGVFLYTSKEK-----STFINMTRVDSDMNDAYLGYAAAIILR 413
+ +G LL VG+YDW G V TS K +++ + + AYLGY ++
Sbjct: 375 VVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVS 434
Query: 414 NRVQSL-VLGAPRYQHIGLVAMFRQ-NTGMWESNANVKGTQIGAYFGASLCSVDVDSNGS 471
+R + V GAPR+ H G V +F N + ++G QIG+YFG+ + SVD+D +G
Sbjct: 435 SRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGV 494
Query: 472 TDLVLIGAPHYYEQTRG-GQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGD 530
TD++L+GAP Y+ + R G+V V L ++ + + L RFG+++ + D
Sbjct: 495 TDVLLVGAPMYFNEGRERGKVYVYEL---RQNLFVYNGTLKDSHSYQNARFGSSIASVRD 551
Query: 531 VNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSG 590
+N D DV +GAP E+++ GA+Y+FHG GS I + QRI S+L+ LQYFG S+ G
Sbjct: 552 LNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHG 610
Query: 591 GQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVF--ECNDQVVKGKE 648
DL DGL+DL VGA G+ ++L S+PV+++ A + F P ++ N+F +C K
Sbjct: 611 QLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKI--NIFHRDC-------KR 661
Query: 649 AGEVRVCLHVQKSTRDRLREGQIQSV---VTYDLALDSGRPHSRAVFNETKNS-TRRQTQ 704
+G CL Q+ + Y+ +D R RA +E + T R
Sbjct: 662 SGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVL 721
Query: 705 VLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTAL 764
+ + CE + + + D V P+ + +SL + P+L +
Sbjct: 722 LSSGQELCERINFHVLD-TADYVKPVTFSVEYSLEDP------DHGPMLDDGWPTTLRVS 774
Query: 765 FPFEKNCGNDNICQDDL---------------------------SITFSFMSLDCLVVGG 797
PF C D C DL + T SF + ++
Sbjct: 775 VPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIEST 834
Query: 798 PREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVS 857
+ V T+ N GE++Y T + +L + S +Q + S S E
Sbjct: 835 RQRVAVEATLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECVNEER------ 886
Query: 858 GALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTE-- 915
L+ C++++P F ++V F + F+ SK+ + L ++ S++N + K +
Sbjct: 887 -RLQKQVCNVSYPFFRAKAKVAFRLDFEF-SKSIFLHHLEIELAAGSDSNERDSTKEDNV 944
Query: 916 FQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQ--------YQVSNLGQ---R 964
L +KY ++ T S+ ++ N+S +++ NLG
Sbjct: 945 APLRFHLKYEADVLFTR---SSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIH 1001
Query: 965 SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1024
+ + + + R ++ R +T N S + +LR+AP +N S
Sbjct: 1002 GMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHS 1061
Query: 1025 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1084
+ I C+I +E N L GNL W L + +I+ N ++
Sbjct: 1062 NSDVVSINCNIRLVP-NQEINFHLLGNL---WLRSLK---ALKYKSMKIMVNAALQRQFH 1114
Query: 1085 GQGAFVRSQTETKVEPFEVPN------PLPLIVGSSVGGLLLLALITAALYKLGFFK 1135
F R + ++ FE+ P+ +IVGS++GGLLLLAL+ AL+KLGFF+
Sbjct: 1115 SPFIF-REEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 375 bits (964), Expect = e-103
Identities = 335/1201 (27%), Positives = 543/1201 (45%), Gaps = 128/1201 (10%)
Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSVVQL---QGSRVVVGAPQEIVAANQRGSLYQC 66
L C +N+ A F ++ FG +V Q +G+ ++VG+P N+ G +Y+C
Sbjct: 24 LNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKC 83
Query: 67 --DYSTGSCEPIRLQVPVEA-------VNMSLGLSLAATTSPPQLLACGPTVHQTCSENT 117
D ST +CE + LQ NMSLGL L L CGP Q C
Sbjct: 84 PVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQY 143
Query: 118 YVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVM 177
Y G+C + Q F A + CP D+ + D S SI P D +K F+ +
Sbjct: 144 YTTGVCSDISPDF-QLSASFSPATQPCPSL-IDVVVVCDESNSIYPWD--AVKNFLEKFV 199
Query: 178 EQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKV 234
+ L +KT L+QY+ R+ F ++ +Q G T+T I+
Sbjct: 200 QGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYA 259
Query: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGV-----GD 289
+ ++ +G R++A K++VV+TDGE + + VI + + + ++R+ I V +
Sbjct: 260 RKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCNHDNILRFGIAVLGYLNRN 318
Query: 290 AFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHE 349
A ++ +E+ IAS P + F V++ AL L E+IF+IEGT G + F+ E
Sbjct: 319 ALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDN-FQME 377
Query: 350 MSQEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINMT--RVDSDMN-DAYL 404
MSQ GFSA +S +L VG++ W+G + TS F ++ D N +YL
Sbjct: 378 MSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYL 437
Query: 405 GYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV------KGTQIGAYFG 458
GY+ A I V GAPR + G + ++ N N N+ +G QIG+YFG
Sbjct: 438 GYSVAAISTGESTHFVAGAPRANYTGQIVLYSVN-----ENGNITVIQAHRGDQIGSYFG 492
Query: 459 ASLCSVDVDSNGSTDLVLIGAPHYYEQTRG--GQVSVCPLPRGQRARWQCDAVLYGEQGQ 516
+ LCSVDVD + TD++L+GAP Y + G+V + + G + Q L G +G
Sbjct: 493 SVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQ---FLEGPEGI 549
Query: 517 PWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSK 576
RFG+A+ L D+N D DV +G+P E N GAVY+++G G+ I +SQ+I GS
Sbjct: 550 ENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGT-IRTKYSQKILGSD 608
Query: 577 LSPR--LQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVAR 634
+ R LQYFG+SL G DL D + D+++GA G V+ L SQ + V F P ++
Sbjct: 609 GAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKIT- 667
Query: 635 NVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALD----SGRPHSRA 690
+ N Q++ +++C S + R + Q + Y++ LD S R SR
Sbjct: 668 -LVNKNAQII-------LKLCF----SAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRG 715
Query: 691 VFNETKNSTRRQTQVLGLTQTC--ETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGN 748
+F E ++ V+ Q+C + +Q P+ D V+ + LR++ SL S
Sbjct: 716 LFKENNERCLQKNMVVNQAQSCPEHIIYIQEPS---DVVNSLDLRVDISLENPGTS---- 768
Query: 749 LRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF----SFMSLDCLVVGGPREFNVT 804
P L ++ PF K+CG D +C DL + + +V + +
Sbjct: 769 --PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFS 826
Query: 805 VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASST-EVSGALKST 863
VT++N E +Y T + F +L + S+ L + T +V+ + KS
Sbjct: 827 VTLKNKRESAYNTGIVVDFSENLFFA------------SFSLPVDGTEVTCQVAASQKSV 874
Query: 864 SCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVK 923
+C + +P +VTF I FD + + +L N+ L SE+ L++P+
Sbjct: 875 ACDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADNLVNLKIPLL 933
Query: 924 YAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQR---SLPISLVFLVPVRLNQ 980
Y + H + +NF + V + ++G + SL ++ VPV +
Sbjct: 934 YDAEI----HLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM-A 987
Query: 981 TVIWDRPQVTFSENL-------------SSTCHTK------ERLPSHSDFLAE-LRKAPV 1020
TVI PQ T +N +C+ + S F +E R
Sbjct: 988 TVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKE 1047
Query: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080
+NC A C + C + ++ E+ + + + ++ + + + AEI +
Sbjct: 1048 LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEI 1107
Query: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140
++ + E EVP + I+GS + G+LLL + A L+KLGFFKR+Y+
Sbjct: 1108 YVIEDNTVTIPLMIMKPDEKAEVPTGV--IIGSIIAGILLLLALVAILWKLGFFKRKYEK 1165
Query: 1141 M 1141
M
Sbjct: 1166 M 1166
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 212 bits (540), Expect = 1e-54
Identities = 223/862 (25%), Positives = 365/862 (42%), Gaps = 114/862 (13%)
Query: 352 QEGFSAAITSNGPLLSTVGSYDWAGGVFLY---TSKEKSTFINMTRVDSDMNDAYLGYA- 407
Q G S+ T + ++ GS W G +F+Y T+K K+ +V +YLGY+
Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFG---SYLGYSV 255
Query: 408 -AAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDV 466
A +V GAP+++ IG +F + +KG ++G+YFGAS+C+VD+
Sbjct: 256 GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDL 315
Query: 467 DSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALT 526
+++G +DL L+GAP G+V V + L G RFG ++
Sbjct: 316 NADGFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIV 373
Query: 527 VLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQ 586
LGD++ D DVAIGAP E+D +GA+Y+++G + GIS + SQRI G ++S L FGQ
Sbjct: 374 NLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRA-DGISSTFSQRIEGLQISKSLSMFGQ 432
Query: 587 SLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVV 644
S+SG D +G VD+ VGA +LLR++PV+ V A + +P V R F+C
Sbjct: 433 SISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDC----- 486
Query: 645 KGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGR-----PHSRAVFNETKNST 699
E G VC+ + + +E V+ Y+++LD R P N T +
Sbjct: 487 --VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVI 544
Query: 700 RRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLS-----AFGNLRPVLA 754
QV C T + + + D ++PI + + L +S F L+P+L
Sbjct: 545 TGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQ 604
Query: 755 EDAQR-LFTALFPFEKNCGNDNICQDDLSITFSFMSL------DCLVVGGPREFNVTVTV 807
+ ++ + F + C ++N C DL ++ L L VG + + V++
Sbjct: 605 QKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSL 663
Query: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
N G+D+Y T + P+ L + K+ L+ + ++ CE T+ SG ++ CSI
Sbjct: 664 FNAGDDAYETTLHVKLPVGLYFIKILELEEK------QINCE---VTDNSGVVQ-LDCSI 713
Query: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN--NMPRTNKTEFQLELPVKYA 925
+ S + + DV S + L + + T EN M + + +P+KY
Sbjct: 714 GYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYE 773
Query: 926 VYMVVTSHGVSTKYLNFTASENTSRV-----MQHQYQVSNLGQRSLP-ISLVFLVPVRLN 979
V + V T ++ + EN M + V N G P +S+ +VP +
Sbjct: 774 VKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFS 833
Query: 980 QTV-----IWDRPQVT---FSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1031
I D T EN C +++ + +R + + C I
Sbjct: 834 PQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYC--I 891
Query: 1032 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1091
+ D F G K + H+ + IL D L
Sbjct: 892 KADPHCLNFLCNFGKMESG--------KEASVHIQLEGRPSILEMDETSAL--------- 934
Query: 1092 SQTETKVEPFEVPNP-----------------------------LPLIVGSSVGGLLLLA 1122
+ E + F PNP + +I S + GL++L
Sbjct: 935 -KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLL 993
Query: 1123 LITAALYKLGFFKRQYKDMMSE 1144
LI+ ++K GFFKRQYK ++ E
Sbjct: 994 LISYVMWKAGFFKRQYKSILQE 1015
Score = 32.7 bits (73), Expect = 2.0
Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 27/159 (16%)
Query: 5 VLLLTALTLCHG--FNLDTENAMTFQ-ENARGFGQSVV-QLQGSR--VVVGAPQEIVAAN 58
V+LL L + G +N+DTE+A+ +Q + FG SVV G+ ++VGAP AN
Sbjct: 20 VMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLVGAPTANWLAN 79
Query: 59 ----QRGSLYQCDYSTG---SCEPIRLQVP----------VEAVNMSLGLSLAATTSP-P 100
G++Y+C +CE ++L P E N LG++L+
Sbjct: 80 ASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENG 139
Query: 101 QLLACG---PTVHQTCSENTYVKGLCFLFGSNLRQQPQK 136
++ CG + +EN G C+ +LR + K
Sbjct: 140 SIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSK 178
Score = 31.6 bits (70), Expect = 4.5
Identities = 39/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 462 CSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRF 521
C + S + DL+++GAP T G + V + + A L + +G +
Sbjct: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTN-----KYKAFLDKQNQVKFGSY 250
Query: 522 GAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRL 581
G T+V GAP + + G Y+F ++ H + G KL
Sbjct: 251 LGYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG--- 303
Query: 582 QYFGQSLSGGQDLTMDGLVDLTVGA 606
YFG S+ DL DG DL VGA
Sbjct: 304 SYFGASVC-AVDLNADGFSDLLVGA 327
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 209 bits (533), Expect = 9e-54
Identities = 229/861 (26%), Positives = 387/861 (44%), Gaps = 100/861 (11%)
Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
EH Q G + T ++ GS+ WAG + + + + V + YLGY
Sbjct: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGY 249
Query: 407 A--AAIILRNRVQSLVLGAPRYQHIGLVAMFR--QNTGMWESNANVKGTQIGAYFGASLC 462
A A +V GAP+ + IG V +FR + +G G ++G+YFG+SLC
Sbjct: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLC 309
Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFG 522
+VD++ +G +DL L+GAP + E GQV+V + RG A + L G+ G FG
Sbjct: 310 AVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEE-QLALTGD-GAYNAHFG 365
Query: 523 AALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQ 582
++ L D++ D DVAIGAP E+D GAVY++HG +G GI P +S +++G K++P L+
Sbjct: 366 ESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLR 424
Query: 583 YFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECN 640
FGQS+SGG D+ +G D+TVGA V+LLR++PV+ V + F P + +C+
Sbjct: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVD-VSIFLPGSINITAPQCH 483
Query: 641 DQVVKGKEAGEVRV-CLHVQK--STRDRLREGQI--QSVVTYDLALDSGRPHSRAVF--- 692
D G+ V CL+V S + G+I V+ D+A R F
Sbjct: 484 D--------GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLL 535
Query: 693 NETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL----VGTPLSAFGN 748
ET + Q+ + +TC + ++D +SPIV +SL G
Sbjct: 536 GETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPP 595
Query: 749 LRPVL-----AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFM--SLD----CLVVGG 797
L PVL + AQ+ T FE+NC +++ C DL + + S+D L +G
Sbjct: 596 LTPVLRWKKGQKIAQKNQTV---FERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGA 651
Query: 798 PREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVS 857
+ ++ +++ N G+D+Y V+F +L + N + ++CE S +
Sbjct: 652 VKNISLNISISNLGDDAYDANVSFNVSRELFF------INMWQKEEMGISCELLESDFL- 704
Query: 858 GALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT---NK 913
CS+ P S+ F++ FD + G + +L VT+++ N R+ +
Sbjct: 705 ------KCSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHD 756
Query: 914 TEFQLELPVKYAVYMVVTS--------HGVSTKYLNFTASENTS---RVMQHQYQVSNLG 962
L +P+ + V +T +G S NF ++ + + QV N G
Sbjct: 757 NTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTG 816
Query: 963 QRSLPISLVFL-VPVRLN-----------QTVIWDRPQVTFSENLSSTCHTKERLPSHSD 1010
+LP S V + P RL+ V ++ +F +N + +E+
Sbjct: 817 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 876
Query: 1011 FLAELRKA--PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLL 1066
A K+ V++C C C+ +E + L+ + K S + +
Sbjct: 877 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 936
Query: 1067 IVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVG-----SSVGGLLLL 1121
+S A++ + ++ + G + E P +VG S + G+L+
Sbjct: 937 FMSRAKVKVDPALRVVEIAHGN--PEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIF 994
Query: 1122 ALITAALYKLGFFKRQYKDMM 1142
L+ L+K+GFF+R+YK+++
Sbjct: 995 LLLAVLLWKMGFFRRRYKEII 1015
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 167 bits (423), Expect = 5e-41
Identities = 220/858 (25%), Positives = 365/858 (42%), Gaps = 108/858 (12%)
Query: 352 QEGFSAAITSNGPL-LSTVGSYDWAGGVFLYTSKEKST------FINMTR-------VDS 397
Q GFSA T G + L GSY W G + T ++ + IN+ + S
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASS 265
Query: 398 DMNDAYLGYAAAI--ILRNRVQSLVLGAPR----YQHIGLVAMFRQNTGMWESNANVKGT 451
+D+YLGY+ A+ + + V G P+ Y ++ ++ N S N G
Sbjct: 266 IYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTIL-----NGSDIRSLYNFSGE 320
Query: 452 QIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG---QVSVCPLPRGQRARWQCDA 508
Q+ +YFG ++ + DV+ +G DL L+GAP ++T G +V + A +
Sbjct: 321 QMASYFGYAVAATDVNGDGLDDL-LVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTP 379
Query: 509 VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF-HGTSGSGISP 566
L +GRFG++LT LGD++ D DVAIGAP G E +G V++F G G G P
Sbjct: 380 TLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKP 439
Query: 567 SH-SQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKA 623
S Q + + +P +FG +L GG+DL +G DL VG+ G ++ R +P++ A
Sbjct: 440 SQVLQPLWAASHTP--DFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASA 497
Query: 624 IME-----FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYD 678
+ FNP E + ++ G C+++ + T +
Sbjct: 498 SLTIFPAMFNPEERSCSL------------EGNPVACINLSFCLNASGKHVADSIGFTVE 545
Query: 679 LALDSGRPHS---RAVFNETKNSTRRQTQVL--GLTQTCETLKLQLPNCIE--DPVSPIV 731
L LD + RA+F ++ +T QT ++ G + C +K+ L N E D +SPI
Sbjct: 546 LQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIH 605
Query: 732 LRLNFSL-VGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSL 790
+ LNFSL P+ + G LRP L ++ +CG DNIC DL + F
Sbjct: 606 IALNFSLDPQAPVDSHG-LRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV-FGEQ 663
Query: 791 DCLVVGGPREFNVTVTVRNDGE-DSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACE 849
+ + +G N+T +N GE +Y ++ P + Y + S L+C+
Sbjct: 664 NHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSS----LSCD 719
Query: 850 SASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NM 908
+ + + C + +P+ + + + F V + + S+N N
Sbjct: 720 YFAVNQ----SRLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNN 774
Query: 909 PRTNKTEFQLELPVKYAVYMVVTSHGVS-TKYLNFTAS-----------ENTSRVMQHQY 956
+++ F+L + + VT +GVS + + F S E+ + H Y
Sbjct: 775 SQSDVVSFRLSVEAQ----AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVY 830
Query: 957 QVSNLGQRSLPISLVFL-VPVRLNQTVIWDRPQVT---FSENLSSTCHTKERLPSHSDFL 1012
++ N G S+ ++ L P L + +VT + N E P S
Sbjct: 831 ELINQGPSSISQGVLELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHH 890
Query: 1013 AELRKAP----------VVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSH 1062
+ R+AP ++ C A C R++C++ QE + L + +++ H
Sbjct: 891 QQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREH 950
Query: 1063 NHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN----PLPLIVGSSVGGL 1118
+ A + +LP Q Q T V+ + PL +I+ + + GL
Sbjct: 951 QPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGL 1010
Query: 1119 LLLALITAALYKLGFFKR 1136
LLL L+ LYKLGFFKR
Sbjct: 1011 LLLGLLIYILYKLGFFKR 1028
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 167 bits (422), Expect = 7e-41
Identities = 200/857 (23%), Positives = 358/857 (41%), Gaps = 91/857 (10%)
Query: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396
Q GFS T ++ LL GS+ W G + +Y+ K + T
Sbjct: 140 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 198
Query: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453
+ +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+
Sbjct: 199 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 256
Query: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGE 513
AYFG S+ + D++ + D V IGAP + ++ G++ R D
Sbjct: 257 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKL 315
Query: 514 QG-QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQR 571
G + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ
Sbjct: 316 NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQI 374
Query: 572 IAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFN 628
+ G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E
Sbjct: 375 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 434
Query: 629 PREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRP 686
P + ++ C+ K VR CL K R Q++ ++ L
Sbjct: 435 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIR 493
Query: 687 HSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLS 744
+ +++ + + ++ T G CE L L + E D ++PI + + + L +
Sbjct: 494 RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 553
Query: 745 AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVT 804
L+P+L + + +CG DN+C+ L ++ + +G +
Sbjct: 554 DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLI 612
Query: 805 VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTS 864
V +N GE +Y ++ PL + + ++N + RL+C A TE +
Sbjct: 613 VKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVV 664
Query: 865 CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 924
C + +P+ +++ + F V ++ + + + S N + + + V
Sbjct: 665 CDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDL 720
Query: 925 AVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVF 972
AV V GVS+ +L N E+ V+QH Y++ N G S +++
Sbjct: 721 AVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLH 780
Query: 973 LV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERL 1005
L P + N + D P Q T + + ++ L
Sbjct: 781 LQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL 840
Query: 1006 PSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH 1064
+ D + C +A C +I C + + +K L + ++ K + NH
Sbjct: 841 ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNH 900
Query: 1065 -LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLL 1119
+ S+A + + LP V + ++P +P P+ +I+ + + GLL
Sbjct: 901 SYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLL 960
Query: 1120 LLALITAALYKLGFFKR 1136
LLA++ +Y++GFFKR
Sbjct: 961 LLAVLVFVMYRMGFFKR 977
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 167 bits (422), Expect = 7e-41
Identities = 200/857 (23%), Positives = 358/857 (41%), Gaps = 91/857 (10%)
Query: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396
Q GFS T ++ LL GS+ W G + +Y+ K + T
Sbjct: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244
Query: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453
+ +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+
Sbjct: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302
Query: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGE 513
AYFG S+ + D++ + D V IGAP + ++ G++ R D
Sbjct: 303 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKL 361
Query: 514 QG-QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQR 571
G + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ
Sbjct: 362 NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQI 420
Query: 572 IAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFN 628
+ G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E
Sbjct: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480
Query: 629 PREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRP 686
P + ++ C+ K VR CL K R Q++ ++ L
Sbjct: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIR 539
Query: 687 HSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLS 744
+ +++ + + ++ T G CE L L + E D ++PI + + + L +
Sbjct: 540 RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 599
Query: 745 AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVT 804
L+P+L + + +CG DN+C+ L ++ + +G +
Sbjct: 600 DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLI 658
Query: 805 VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTS 864
V +N GE +Y ++ PL + + ++N + RL+C A TE +
Sbjct: 659 VKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVV 710
Query: 865 CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 924
C + +P+ +++ + F V ++ + + + S N + + + V
Sbjct: 711 CDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDL 766
Query: 925 AVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVF 972
AV V GVS+ +L N E+ V+QH Y++ N G S +++
Sbjct: 767 AVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLH 826
Query: 973 LV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERL 1005
L P + N + D P Q T + + ++ L
Sbjct: 827 LQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL 886
Query: 1006 PSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH 1064
+ D + C +A C +I C + + +K L + ++ K + NH
Sbjct: 887 ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNH 946
Query: 1065 -LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLL 1119
+ S+A + + LP V + ++P +P P+ +I+ + + GLL
Sbjct: 947 SYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLL 1006
Query: 1120 LLALITAALYKLGFFKR 1136
LLA++ +Y++GFFKR
Sbjct: 1007 LLAVLVFVMYRMGFFKR 1023
Score = 31.6 bits (70), Expect = 4.5
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)
Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
L LC FNLD ++ + FG +V V SR ++VGAP+ + G
Sbjct: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
Query: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
+ +CD+ ST C+PI P+E + + ++LAC P H
Sbjct: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
Query: 111 --QTCSENTYVKGLCFL 125
+ G CFL
Sbjct: 144 WRTEMKQEREPVGTCFL 160
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 167 bits (422), Expect = 7e-41
Identities = 210/871 (24%), Positives = 364/871 (41%), Gaps = 123/871 (14%)
Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
E M Q G S T N G+Y+W G ++ KE + D + Y+GY
Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252
Query: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462
+ IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++
Sbjct: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312
Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGR 520
D++++G DL L+GAP+Y+E+ GG + V G +L+G G
Sbjct: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368
Query: 521 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 579
FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425
Query: 580 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 636
L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR +
Sbjct: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482
Query: 637 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 696
C +V +C +S + I + Y L D R R F ++
Sbjct: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535
Query: 697 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 750
++ + C+ L+L L + + D + PI++ +N+SL + P LR
Sbjct: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594
Query: 751 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 804
P+L + F+K CG DN C+ +L + +F+S + R+ ++
Sbjct: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654
Query: 805 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 858
+ V N GED++ +T P L V AC+
Sbjct: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695
Query: 859 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 918
A ++ C + +P F N + I F+V L ++ +++ ++ + N L
Sbjct: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752
Query: 919 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 969
L V Y + + + +H + + + E+ +++++QV +G+ + +
Sbjct: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812
Query: 970 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1010
L++ + ++ W RP L+ T PS
Sbjct: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872
Query: 1011 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1049
LA +KA V+ C+ A C ++C IP + N T+K
Sbjct: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930
Query: 1050 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1105
+ +I+ + + + A + S+ T+ + + + +++ VE
Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
Query: 1106 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136
L L++ + GLLLL LI L+K GFFKR
Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 164 bits (415), Expect = 4e-40
Identities = 209/871 (23%), Positives = 363/871 (41%), Gaps = 123/871 (14%)
Query: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
E M Q G S T N G+Y+W G ++ KE + D + Y+GY
Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGY 252
Query: 407 AAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV-KGTQIGAYFGASLC 462
+ IL + ++V GAPR++H+G V + Q G V +G+Q+GAYFG+++
Sbjct: 253 TMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIA 312
Query: 463 SVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGR 520
D++++G DL L+GAP+Y+E+ GG + V G +L+G G
Sbjct: 313 LADLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SA 368
Query: 521 FGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLS-P 579
FG ++ +GD+N D D+A+GAP E G VY++H +S G+ Q I G KL P
Sbjct: 369 FGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYH-SSSKGLLRQPQQVIHGEKLGLP 425
Query: 580 RLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLRV--KAIMEFNPREVARNV 636
L FG SLSG D+ + DL VG+ H++LLR++PV+ + K ++ PR +
Sbjct: 426 GLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV---PRPAVLDP 482
Query: 637 FECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETK 696
C +V +C +S + I + Y L D R R F ++
Sbjct: 483 ALCT-----ATSCVQVELCFAYNQSAGNPNYRRNI--TLAYTLEADRDRRPPRLRFAGSE 535
Query: 697 NSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL-VGTPLSAFGNLR----- 750
++ + C+ L+L L + + D + PI++ +N+SL + P LR
Sbjct: 536 SAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAY 594
Query: 751 PVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG------GPREFNVT 804
P+L + F+K CG DN C+ +L + +F+S + R+ ++
Sbjct: 595 PILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLS 654
Query: 805 VTVRN------DGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 858
+ V N GED++ +T P L V AC+
Sbjct: 655 INVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPG----------ACQ--------- 695
Query: 859 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQL 918
A ++ C + +P F N + I F+V L ++ +++ ++ + N L
Sbjct: 696 ANETIFCELGNP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSH--QDNLWPMIL 752
Query: 919 ELPVKYAVY--MVVTSHGVSTKY-------LNFTASENTSRVMQHQYQVSNLGQRSLPIS 969
L V Y + + + +H + + + E+ +++++QV +G+ + +
Sbjct: 753 TLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLG 812
Query: 970 -----------------LVFLVPVRLNQTVIWD-RPQVTFSENLSSTCHTKERLPSHSD- 1010
L++ + ++ W RP L+ T PS
Sbjct: 813 TLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQR 872
Query: 1011 ----------------FLAELRKA---PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLK 1049
LA +KA V+ C+ A C ++C IP + N T+K
Sbjct: 873 RRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVT--NVTVK 930
Query: 1050 GNLSFDWYIK--TSHNHLLIVSTAEILFNDSVFTL-LPGQGAFVRSQTETK-VEPFEVPN 1105
+ +I+ + + + A + S+ T+ + + + +++ VE
Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
Query: 1106 PLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136
L L++ + GLLLL LI L+K FFKR
Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCDFFKR 1021
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 163 bits (412), Expect = 1e-39
Identities = 186/794 (23%), Positives = 336/794 (42%), Gaps = 75/794 (9%)
Query: 400 NDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQIGAY 456
+D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ AY
Sbjct: 212 DDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQMAAY 269
Query: 457 FGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQG- 515
FG S+ + D++ + D V IGAP + ++ G++ R D G
Sbjct: 270 FGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGF 328
Query: 516 QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQRIAG 574
+ + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ + G
Sbjct: 329 EVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQILEG 387
Query: 575 SKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFNPRE 631
+ + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E P
Sbjct: 388 QWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI 447
Query: 632 VARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHSR 689
+ ++ C+ K VR CL K R Q++ ++ L +
Sbjct: 448 LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIRRAL 506
Query: 690 AVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLSAFG 747
+++ + + ++ T G CE L L + E D ++PI + + + L +
Sbjct: 507 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 566
Query: 748 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTV 807
L+P+L + + +CG DN+C+ L ++ + +G + V
Sbjct: 567 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKA 625
Query: 808 RNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSI 867
+N GE +Y ++ PL + + ++N + RL+C A TE + C +
Sbjct: 626 QNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVVCDL 677
Query: 868 NHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVY 927
+P+ +++ + F V ++ + + + S N + + + V AV
Sbjct: 678 GNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDLAVL 733
Query: 928 MVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVFLV- 974
V GVS+ +L N E+ V+QH Y++ N G S +++ L
Sbjct: 734 AAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQW 793
Query: 975 PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERLPSH 1008
P + N + D P Q T + + ++ L +
Sbjct: 794 PYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITK 853
Query: 1009 SDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH-LL 1066
D + C +A C +I C + + +K L + ++ K + NH
Sbjct: 854 RDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913
Query: 1067 IVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLA 1122
+ S+A + + LP V + ++P +P P+ +I+ + + GLLLLA
Sbjct: 914 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973
Query: 1123 LITAALYKLGFFKR 1136
++ +Y++GFFKR
Sbjct: 974 VLVFVMYRMGFFKR 987
Score = 31.6 bits (70), Expect = 4.5
Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)
Query: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61
L LC FNLD ++ + FG +V V SR ++VGAP+ + G
Sbjct: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
Query: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110
+ +CD+ ST C+PI P+E + + ++LAC P H
Sbjct: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
Query: 111 --QTCSENTYVKGLCFL 125
+ G CFL
Sbjct: 144 WRTEMKQEREPVGTCFL 160
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 157 bits (396), Expect = 7e-38
Identities = 216/903 (23%), Positives = 387/903 (42%), Gaps = 157/903 (17%)
Query: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
Q+G +A T + + G+Y+W G + ++ +TF +M T D
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246
Query: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
+ ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++
Sbjct: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301
Query: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQ 500
G + + FG + VD++ +G D+V IGAP Y+++ GG V V Q
Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVY---MNQ 357
Query: 501 RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 560
+ RW + G FG A+ +GD+N D D+A+GAP D+ G V+++HG S
Sbjct: 358 QGRWN-NVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-S 413
Query: 561 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVL 619
+GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+
Sbjct: 414 ANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVI 468
Query: 620 RVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDL 679
++ + P + + + G +G +CL V+ ++
Sbjct: 469 NIQKTITVTPNRI-----DLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVG 520
Query: 680 ALDSGRPHSRAVFNE-----TKNSTRRQTQVLGLTQ----TCETLKLQLPNCIEDPVSPI 730
L++ + ++ + + S + TQ L L + C L L + I D + PI
Sbjct: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
Query: 731 VLRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITF 785
+ + + +++ + P+L D + F K CG+DN+C +L + +
Sbjct: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
Query: 786 SFMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQV 819
F + + LV+ ++ + +TV N DG+D++ ++
Sbjct: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
Query: 820 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 879
FP L+Y S + R+ +L+C + + C + +P F NS VT
Sbjct: 701 IATFPDTLTY---SAYRELRAFPEKQLSCVANQNGS------QADCELGNP-FKRNSNVT 750
Query: 880 F-------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA------- 925
F +TFD L L L+ +N P T K + +EL + +
Sbjct: 751 FYLVLSTTEVTFDTPD---LDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQ 807
Query: 926 VYM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVF 972
VY VV + ++ + E RV+ ++NLG +L I L++
Sbjct: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLY 867
Query: 973 LVPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVN 1022
LV V + V + + S NL+ + + T++++ + F L RK +N
Sbjct: 868 LVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLN 927
Query: 1023 CSIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSV 1079
CS+ V C I+C P G+ + + L+ L +++ + N+L I+ A I +
Sbjct: 928 CSVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA 985
Query: 1080 FTL-LPGQGAFVRSQT-ETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQ 1137
+ LP G VR +K P +I+ + + G+L+LAL+ L+K GFFKR
Sbjct: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRN 1045
Query: 1138 YKD 1140
KD
Sbjct: 1046 KKD 1048
Score = 31.6 bits (70), Expect = 4.5
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L
Sbjct: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83
Query: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
Y CD + G C I + + S +G+++ + +++ C + T
Sbjct: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143
Query: 113 CSENTYVKGLCFLFGSNLR 131
E+ + G C++ NLR
Sbjct: 144 KQESRDIFGRCYVLSQNLR 162
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 154 bits (389), Expect = 5e-37
Identities = 217/903 (24%), Positives = 387/903 (42%), Gaps = 157/903 (17%)
Query: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
Q+G +A T + + G+Y+W G + ++ +TF +M T D
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246
Query: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
+ ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++
Sbjct: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301
Query: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQ 500
G + + FG + VD++ +G D+V IGAP Y+++ GG V V Q
Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVY---MNQ 357
Query: 501 RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 560
+ RW + G FG A+ +GD+N D D+A+GAP D+ G V+++HG S
Sbjct: 358 QGRWN-NVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-S 413
Query: 561 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVL 619
+GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+
Sbjct: 414 ANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVI 468
Query: 620 RVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDL 679
++ + P N + + G +G +CL V+ ++
Sbjct: 469 NIQKTITVTP-----NRIDLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVG 520
Query: 680 ALDSGRPH-----SRAVFNETKNSTRRQTQVLGL----TQTCETLKLQLPNCIEDPVSPI 730
L++ + S V + S + TQ L L + C L L + I D + PI
Sbjct: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
Query: 731 VLRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPF-EKNCGNDNICQDDLSITF 785
+ + + +++ + P+L D + F ++ CG+DN+C +L + +
Sbjct: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
Query: 786 SFMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQV 819
F + + LV+ ++ + +TV N DG+D++ ++
Sbjct: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
Query: 820 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 879
FP L+Y S + R+ +L+C + + C + +P F NS VT
Sbjct: 701 IATFPDTLTY---SAYRELRAFPEKQLSCVANQNG------SQADCELGNP-FKRNSNVT 750
Query: 880 F-------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA------- 925
F +TFD L L L+ +N P T K + +EL + +
Sbjct: 751 FYLVLSTTEVTFDT---PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQ 807
Query: 926 VYM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVF 972
VY VV + ++ + E RV+ ++NLG +L I L++
Sbjct: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLY 867
Query: 973 LVPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVN 1022
LV V + V + + S NL+ + + T++++ + F L RK +N
Sbjct: 868 LVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLN 927
Query: 1023 CSIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSV 1079
CS+ V C I+C P G+ + + L+ L +++ + N+L I+ A I +
Sbjct: 928 CSVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA 985
Query: 1080 FTL-LPGQGAFVR-SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQ 1137
+ LP G VR + +K P +I+ + + G+L+LAL+ L+K GFFKR
Sbjct: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRS 1045
Query: 1138 YKD 1140
D
Sbjct: 1046 RYD 1048
Score = 31.6 bits (70), Expect = 4.5
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L
Sbjct: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83
Query: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
Y CD + G C I + + S +G+++ + +++ C + T
Sbjct: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143
Query: 113 CSENTYVKGLCFLFGSNLR 131
E+ + G C++ NLR
Sbjct: 144 KQESRDIFGRCYVLSQNLR 162
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 153 bits (386), Expect = 1e-36
Identities = 204/869 (23%), Positives = 364/869 (41%), Gaps = 112/869 (12%)
Query: 352 QEGFSAAITSNGPLL-STVGSYDWAGGVFL---------YTSKE---KSTFINMTRV-DS 397
Q GFS NG L+ GS+ W G V Y+ K+ K T V +
Sbjct: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Query: 398 DMNDAYLGY--AAAIILRNRVQSLVLGAPR-YQHIGLVAMFRQNTGMWESNANVKGTQIG 454
+D+YLGY AA + Q LV G PR Q+ G V++ N+ N G Q+
Sbjct: 261 SYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII--NSTDMTFIQNFTGEQMA 318
Query: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARW-QCDAVLYGE 513
+YFG ++ DV+S+G D VL+GAP + E+ + P GQ + Q ++L+ +
Sbjct: 319 SYFGYTVVVSDVNSDGLDD-VLVGAPLFMER----EFESNPREVGQIYLYLQVSSLLFRD 373
Query: 514 QG-----QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 567
+ +GRFG+A+ LGD+N D D+AIG P +D RG V +++G G++
Sbjct: 374 PQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK-DGLNTK 432
Query: 568 HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAI 624
SQ + G S + FG +L G D+ + DL VGA G V + R++PV+ V A
Sbjct: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
Query: 625 MEFNPREVARNVFECN-DQVVKGKEAGEVRVCLHVQ----KSTRDRLREGQIQSV----- 674
+ +P + C + +RVC V +T + E Q+ S+
Sbjct: 493 LLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGA 552
Query: 675 VTYDLALDSGRPHS-RAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLR 733
+ L LD+ + H + + + S + Q ++ L E D +SPI +
Sbjct: 553 IKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETE---------FRDKLSPINIS 603
Query: 734 LNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCL 793
LN+SL + ++P+L + + + +CG DN+C DL ++ + +
Sbjct: 604 LNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQV 662
Query: 794 VVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR-LACESAS 852
++G + + RN+GE +Y ++ P + Y + +R+ + +R L+CE
Sbjct: 663 IIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI-----ERNNKGFRPLSCE--- 714
Query: 853 STEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT 911
++ + C + +P+ + + + F V + + S N + P +
Sbjct: 715 -YKMENVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDS 772
Query: 912 NKTEFQLELPVKYAVYMVVTSH--GVSTKYLNFTASENTSR------VMQHQYQVSNLGQ 963
N Q+ + V + SH + N+ E + +++H Y++ N+G
Sbjct: 773 NFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGP 832
Query: 964 RSLPISLV-----------FLVPVRLNQTV--IWDRPQVTFSENLSSTCHTKERLPSHSD 1010
++ +++ FL+ + QT+ + +P + + E P S
Sbjct: 833 STISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSA 892
Query: 1011 FLAE------LRK-------------APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGN 1051
FL +RK A ++NC+ C +I C + E ++
Sbjct: 893 FLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSR 952
Query: 1052 LSFDWYIKTSHNHLLIVSTAEILFNDSVFT----LLPGQGAFVRSQTETKVEPFEVPNPL 1107
L +++ ++ + S +T LP +++ PL
Sbjct: 953 LWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPL 1012
Query: 1108 PLIVGSSVGGLLLLALITAALYKLGFFKR 1136
+I+ + + GLL+LA++T AL+K GFF R
Sbjct: 1013 WVIILAILLGLLVLAILTLALWKCGFFDR 1041
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 149 bits (377), Expect = 1e-35
Identities = 214/891 (24%), Positives = 352/891 (39%), Gaps = 155/891 (17%)
Query: 345 SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387
S++ + GFS+ +T G L L G Y + G G+ L+ +S
Sbjct: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251
Query: 388 TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443
++ + + D Y GY+ A+ + V+GAP + +G V + ++
Sbjct: 252 --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306
Query: 444 SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497
++G Q+ +YFG S+ DV+ +G DL L+GAP Y E G+V + P
Sbjct: 307 RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365
Query: 498 RGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF 556
RG A +L G Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F
Sbjct: 366 RGPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVF 423
Query: 557 HGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLR 614
G S G+ SQ + P FG SL G D+ +G DL VGA G V + R
Sbjct: 424 LGQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
Query: 615 SQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQI 671
+QPV++ V V + + VK + + C ++Q
Sbjct: 481 AQPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQ 531
Query: 672 QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC---- 722
+ + +L LD +P R+ +LG Q TL L L P C
Sbjct: 532 KLSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTM 580
Query: 723 --------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGND 774
D +SPIVL LN SL T + P + +CG D
Sbjct: 581 AFLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGED 636
Query: 775 NICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVS 833
++C L +T S L+VG + + N+GE +Y ++ P Y R +S
Sbjct: 637 DVCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALS 695
Query: 834 TLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLG 893
++ RL C E L C + +P+ +N+++ + V + G
Sbjct: 696 NVEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAG 745
Query: 894 NKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR--- 950
+ + + S+N+ +K L++PV+ + + + + A+E R
Sbjct: 746 ESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQN 802
Query: 951 -------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN---------- 979
++H Y++ N G +S P L++++ ++
Sbjct: 803 SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP 862
Query: 980 ---QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQ 1032
V W P + + H ++R LP + + L+ +V+C A C +Q
Sbjct: 863 VNPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQ 920
Query: 1033 CDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPG 1085
CD+ + T+ L+F W L V + FN S LP
Sbjct: 921 CDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977
Query: 1086 QGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136
A V +Q +E E P+ ++ +GGLLLL ++ A++K+GFFKR
Sbjct: 978 GEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 138 bits (347), Expect = 3e-32
Identities = 205/902 (22%), Positives = 357/902 (39%), Gaps = 149/902 (16%)
Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYT--SKEKSTFINMTRVDSDMN------- 400
Q+G +AA + S+ L G+Y+W G +F+ S + + T +D
Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDL 257
Query: 401 --DAYLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANVKGTQIG 454
++YLG++ ++R S V GAPR H G V + R+++ + G ++
Sbjct: 258 ALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLT 317
Query: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQCDAVLYG 512
+ FG SL D++S+G DL+ +GAP+++E+ GG V V Q W + L
Sbjct: 318 SGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAGISPLR- 372
Query: 513 EQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRI 572
G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+ SQ +
Sbjct: 373 LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAKPSQVL 429
Query: 573 AGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIMEFNPRE 631
G + ++ FG SLSG D+ + DL VG+ +L R++P+L V + PR
Sbjct: 430 EGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRS 487
Query: 632 VARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-----RP 686
+ C AG VC+ ++ V D LD+ R
Sbjct: 488 IDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRG 538
Query: 687 HSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRLNFSLV 739
V ++N + Q G + C QL ++D + IV+ L++SL
Sbjct: 539 QVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ 598
Query: 740 ------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-------- 784
P + P+L A + ++ CG D ICQ +L +
Sbjct: 599 TPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 658
Query: 785 ----FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQVTFFFP 824
F + +D + G + + V N DG+D++ Q+ P
Sbjct: 659 SDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLP 718
Query: 825 LDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITF 884
L Y V L +++ L+ E+AS E C + +P+ ++VTF +
Sbjct: 719 DSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVTFYLIL 766
Query: 885 DVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSHGVSTK 938
+ +L LL A ++ + P + + +ELP+ A+ + GV
Sbjct: 767 STSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 826
Query: 939 YLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL----- 978
+ + ++++ VSN GQ + F L P+++
Sbjct: 827 ERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGG 886
Query: 979 ----NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAELRKAP 1019
+ + RP + + S +E P AE +K
Sbjct: 887 QGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI 946
Query: 1020 VVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFND 1077
++C+ + P + + G L +++ ++ L ++ A I
Sbjct: 947 TLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKS 1006
Query: 1078 SVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALYKLGFF 1134
S+ L+ + V ++P V P +I+ + + GLL+LAL+ L+K+GFF
Sbjct: 1007 SIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFF 1065
Query: 1135 KR 1136
KR
Sbjct: 1066 KR 1067
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 132 bits (331), Expect = 2e-30
Identities = 203/908 (22%), Positives = 354/908 (38%), Gaps = 157/908 (17%)
Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
Q+G +AA + S+ L G+Y+W G + + S ++ +D +A
Sbjct: 101 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 158
Query: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
Y G++ ++R S V GAPR H G V + R+++ +
Sbjct: 159 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 218
Query: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQC 506
G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V Q W
Sbjct: 219 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAG 274
Query: 507 DAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISP 566
+ L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+
Sbjct: 275 ISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVA 330
Query: 567 SHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIM 625
SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V +
Sbjct: 331 KPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 388
Query: 626 EFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG- 684
PR + C AG VC+ ++ V D LD+
Sbjct: 389 SIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADT 439
Query: 685 ----RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLR 733
R V ++N + Q G + C QL ++D + IV+
Sbjct: 440 DRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVT 499
Query: 734 LNFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-- 784
L++SL P + P+L A + ++ CG D ICQ +L +
Sbjct: 500 LSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRA 559
Query: 785 ----------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQ 818
F + +D + G + + V N DG+D++ Q
Sbjct: 560 RFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQ 619
Query: 819 VTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEV 878
+ P L Y V L +++ L+ E+AS E C + +P+ ++V
Sbjct: 620 LLVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQV 667
Query: 879 TFNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTS 932
TF + + +L LL A ++ + P + + +ELP+ A+ +
Sbjct: 668 TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 727
Query: 933 HGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVR 977
GV + + ++++ VSN GQ + F L P++
Sbjct: 728 SGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQ 787
Query: 978 L---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLA 1013
+ + + RP + + S +E P A
Sbjct: 788 VELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA 847
Query: 1014 ELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTA 1071
E +K ++C+ + P + + G L +++ ++ L ++ A
Sbjct: 848 EKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907
Query: 1072 EILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAAL 1128
I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L
Sbjct: 908 NITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL 966
Query: 1129 YKLGFFKR 1136
+K+GFFKR
Sbjct: 967 WKMGFFKR 974
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 132 bits (331), Expect = 2e-30
Identities = 203/908 (22%), Positives = 354/908 (38%), Gaps = 157/908 (17%)
Query: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
Q+G +AA + S+ L G+Y+W G + + S ++ +D +A
Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 255
Query: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
Y G++ ++R S V GAPR H G V + R+++ +
Sbjct: 256 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315
Query: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQC 506
G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V Q W
Sbjct: 316 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAG 371
Query: 507 DAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISP 566
+ L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+
Sbjct: 372 ISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVA 427
Query: 567 SHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIM 625
SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V +
Sbjct: 428 KPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 485
Query: 626 EFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG- 684
PR + C AG VC+ ++ V D LD+
Sbjct: 486 SIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADT 536
Query: 685 ----RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLR 733
R V ++N + Q G + C QL ++D + IV+
Sbjct: 537 DRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVT 596
Query: 734 LNFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-- 784
L++SL P + P+L A + ++ CG D ICQ +L +
Sbjct: 597 LSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRA 656
Query: 785 ----------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQ 818
F + +D + G + + V N DG+D++ Q
Sbjct: 657 RFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQ 716
Query: 819 VTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEV 878
+ P L Y V L +++ L+ E+AS E C + +P+ ++V
Sbjct: 717 LLVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQV 764
Query: 879 TFNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTS 932
TF + + +L LL A ++ + P + + +ELP+ A+ +
Sbjct: 765 TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 824
Query: 933 HGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVR 977
GV + + ++++ VSN GQ + F L P++
Sbjct: 825 SGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQ 884
Query: 978 L---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLA 1013
+ + + RP + + S +E P A
Sbjct: 885 VELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA 944
Query: 1014 ELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTA 1071
E +K ++C+ + P + + G L +++ ++ L ++ A
Sbjct: 945 EKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 1004
Query: 1072 EILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAAL 1128
I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L
Sbjct: 1005 NITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL 1063
Query: 1129 YKLGFFKR 1136
+K+GFFKR
Sbjct: 1064 WKMGFFKR 1071
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 93.6 bits (231), Expect = 1e-18
Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 19/218 (8%)
Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTL--FSLMQYSEEFRIHFTFKEFQ 206
+D+ FLIDGS S+ P +F +K+F+S +++ L S L L+QYS R F F
Sbjct: 274 TDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFH 333
Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
+ ++ V+ ++ + T T ++ ++ F +++GAR A K+ +V TDG
Sbjct: 334 TKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRS----- 388
Query: 267 GYEDVIPEADRE----GVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALK 322
+D I +A ++ G + +GVG+A EL IAS+P +H F +F+ +
Sbjct: 389 --QDYINDAAKKAKDLGFKMFAVGVGNAV-----EDELREIASEPVAEHYFYTADFKTIN 441
Query: 323 TIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAIT 360
I +L++KI +E S + + EG A+T
Sbjct: 442 QIGKKLQKKI-CVEEDPCACESLVKFQAKVEGLLQALT 478
Score = 70.5 bits (171), Expect = 9e-12
Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 13/192 (6%)
Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK--KSKTLFSLMQYSEEFRIHFT 201
C +D+ F++D S S+ P +F ++K F+S V+E L + T ++ Y+ + F+
Sbjct: 35 CRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFS 94
Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNA---FKILVVITD 258
+ + V+ I L T T I+ + + F G R + K+++V+TD
Sbjct: 95 LRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTD 154
Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318
G +DV A GV + IGVG + L IAS+P +HV V ++
Sbjct: 155 GRPQDS---VQDVSARARASGVELFAIGVGSV-----DKATLRQIASEPQDEHVDYVESY 206
Query: 319 EALKTIQNQLRE 330
++ + + +E
Sbjct: 207 SVIEKLSRKFQE 218
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 90.9 bits (224), Expect = 6e-18
Identities = 61/198 (30%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 134 PQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKK---SKTLFSLM 190
P P A C +D+ F++DGS SI +F ++ F+ + + L K T +++
Sbjct: 1016 PPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMV 1075
Query: 191 QYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAF 250
Q++++ R F ++ +K I+ G T T I+ V LF +G R+
Sbjct: 1076 QFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIP 1135
Query: 251 KILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRD 310
K++VVITDG D + E +G + IGV DA S EL +I SKP
Sbjct: 1136 KVIVVITDGRSQDD---VNKISREMQLDGYSIFAIGVADADYS-----ELVSIGSKPSAR 1187
Query: 311 HVFQVNNFEALKTIQNQL 328
HVF V++F+A K I+++L
Sbjct: 1188 HVFFVDDFDAFKKIEDEL 1205
Score = 71.2 bits (173), Expect = 5e-12
Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 16/185 (8%)
Query: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQ 206
+DI L+DGS SI +FR ++ F+ ++ + KT L QYS + RI + F
Sbjct: 157 ADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFS 216
Query: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
V+ + G T T + + F G+R KI ++ITDG+
Sbjct: 217 TKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGK------ 270
Query: 267 GYEDVIPEA---DREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKT 323
+D+IP + GV + IGV +A EL IAS+P HV+ V F+ + T
Sbjct: 271 SQDDIIPPSRNLRESGVELFAIGVKNA-----DVNELQEIASEPDSTHVYNVAEFDLMHT 325
Query: 324 IQNQL 328
+ L
Sbjct: 326 VVESL 330
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 86.7 bits (213), Expect = 1e-16
Identities = 64/238 (26%), Positives = 109/238 (45%), Gaps = 18/238 (7%)
Query: 102 LLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEAL--RGCPQEDSDIAFLIDGSG 159
LL G V +G G + R PQ AL C + +D+ F+ID S
Sbjct: 10 LLILGQIVLLPAEARERSRGRSISRGRHARTHPQT---ALLESSCENKRADLVFIIDSSR 66
Query: 160 SIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKP 217
S+ HD+ ++KEF+ +++ + T L+QY + F+ K F+ VK
Sbjct: 67 SVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKR 126
Query: 218 ITQLLGRTHTATGIRKVVRELFNITNGA---RKNAFKILVVITDGEKFGDPLGYEDVIPE 274
+ L T T I+ + F+ GA R+N ++++++TDG +V +
Sbjct: 127 MRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQD---SVAEVAAK 183
Query: 275 ADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKI 332
A G++ + IGVG + L +I S+P DHVF V NF ++T+ + ++K+
Sbjct: 184 ARDTGILIFAIGVG-----QVDFNTLKSIGSEPHEDHVFLVANFSQIETLTSVFQKKL 236
Score = 75.1 bits (183), Expect = 4e-13
Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 13/194 (6%)
Query: 144 CPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKS--KTLFSLMQYSEEFRIHFT 201
C + D+ F+IDGS S+ +F +K+FV+ +++ L S L+QYS + FT
Sbjct: 649 CTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFT 708
Query: 202 FKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKI---LVVITD 258
+ F + + + V + + + T ++ + F GAR + ++ +V TD
Sbjct: 709 LRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTD 768
Query: 259 GEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNF 318
G D + +A G+ Y +GVG A +EL IAS+P H+F +F
Sbjct: 769 GRAQDD---VSEWASKAKANGITMYAVGVGKAI-----EEELQEIASEPTNKHLFYAEDF 820
Query: 319 EALKTIQNQLREKI 332
+ I +L++ I
Sbjct: 821 STMDEISEKLKKGI 834
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,480,821
Number of Sequences: 37866
Number of extensions: 1883103
Number of successful extensions: 4412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3911
Number of HSP's gapped (non-prelim): 216
length of query: 1153
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1040
effective length of database: 13,968,660
effective search space: 14527406400
effective search space used: 14527406400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.