Guide to the Human Genome
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Search of human proteins with 115496700

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115496700 RGS9 anchor protein [Homo sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115496700 RGS9 anchor protein [Homo sapiens]                       452   e-127
gi|71274166 regulator of G-protein signaling 7 binding protein [...    48   6e-06
gi|223972653 aldehyde dehydrogenase 16 family, member A1 isoform...    30   1.8  
gi|223972651 aldehyde dehydrogenase 16 family, member A1 isoform...    30   1.8  
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          30   2.3  
gi|4505697 pendrin [Homo sapiens]                                      29   3.1  
gi|31542661 transmembrane protein 57 [Homo sapiens]                    29   3.1  
gi|46047467 hypothetical protein LOC389084 [Homo sapiens]              29   3.1  
gi|117938266 hypothetical protein LOC91828 [Homo sapiens]              29   4.0  
gi|21389533 BTB (POZ) domain containing 14A [Homo sapiens]             28   5.2  
gi|32698688 citron [Homo sapiens]                                      28   6.8  
gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens]          28   6.8  
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...    28   8.9  
gi|31377607 mitochondrial fission factor [Homo sapiens]                28   8.9  
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs...    28   8.9  
gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]         28   8.9  
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...    28   8.9  

>gi|115496700 RGS9 anchor protein [Homo sapiens]
          Length = 235

 Score =  452 bits (1162), Expect = e-127
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTA 60
           MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTA
Sbjct: 1   MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTA 60

Query: 61  VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGA 120
           VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGA
Sbjct: 61  VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGA 120

Query: 121 SSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQA 180
           SSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQA
Sbjct: 121 SSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQA 180

Query: 181 AGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS 235
           AGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS
Sbjct: 181 AGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS 235


>gi|71274166 regulator of G-protein signaling 7 binding protein
           [Homo sapiens]
          Length = 257

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 2   AREECKALLDGLNKTTACYHHLVLTVGG-SADSQNLRQELQKTRQKAQELAVSTCARLTA 60
           A ++CK L+   N   A Y  LV+++G  S    +LR E+ KTR K  E+A     +L A
Sbjct: 49  ALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAA 108

Query: 61  VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLH 106
           +        +   E  RL++    CL++   +M +++ L  +   H
Sbjct: 109 ISGPED--GEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFH 152


>gi|223972653 aldehyde dehydrogenase 16 family, member A1 isoform 2
           [Homo sapiens]
          Length = 751

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 5/111 (4%)

Query: 92  DMRRALELG-AAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLREL 150
           D+R A+E    AFP  A + P  R  +  A +    R  ST + RLE +G    A+L+  
Sbjct: 514 DIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQG----AELKAA 569

Query: 151 EREVLQVGEMIDNMEMKVNVPRWTVQARQAAGAELLSTVSAGPSSVVSLQE 201
           E EV      +     +V     T+Q     G  L      G  +VV   E
Sbjct: 570 EAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDE 620


>gi|223972651 aldehyde dehydrogenase 16 family, member A1 isoform 1
           [Homo sapiens]
          Length = 802

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 5/111 (4%)

Query: 92  DMRRALELG-AAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLREL 150
           D+R A+E    AFP  A + P  R  +  A +    R  ST + RLE +G    A+L+  
Sbjct: 565 DIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASRLERQG----AELKAA 620

Query: 151 EREVLQVGEMIDNMEMKVNVPRWTVQARQAAGAELLSTVSAGPSSVVSLQE 201
           E EV      +     +V     T+Q     G  L      G  +VV   E
Sbjct: 621 EAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDE 671


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 2    AREECKALLDGLNKTTACY-HHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCA-RLT 59
            A E  +A+LD L +  A +  ++ +T+  + DS+ +R+  Q+T +K Q+L +   A   T
Sbjct: 2394 AEEPSRAVLDALLEGKAQWGSNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSST 2453

Query: 60   AVLRDRGLAA 69
             V++D    A
Sbjct: 2454 VVMQDESFPA 2463


>gi|4505697 pendrin [Homo sapiens]
          Length = 780

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 7/65 (10%)

Query: 112 LVRTGVAGAS-SGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMID---NMEMK 167
           L+++G   A+ +G+ + A+ST +     E D D+ DL EL+    ++   +D    + +K
Sbjct: 591 LIKSGQLRATKNGIISDAVSTNNA---FEPDEDIEDLEELDIPTKEIEIQVDWNSELPVK 647

Query: 168 VNVPR 172
           VNVP+
Sbjct: 648 VNVPK 652


>gi|31542661 transmembrane protein 57 [Homo sapiens]
          Length = 664

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 47/190 (24%), Positives = 74/190 (38%), Gaps = 34/190 (17%)

Query: 32  DSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADE---RAEFERLWVAFSGCLDL 88
           D + L+ +LQ +RQ  QEL  S  + L++   +RG+ ++    R E E L       + +
Sbjct: 389 DIKKLKADLQASRQVEQELR-SQISSLSST--ERGIRSEMGQLRQENELLQNKLHNAVQM 445

Query: 89  LEADMRRALELGAAFPLHAPRRPLVR--------------------TGVAGASSGVAARA 128
            + D +   +L          R  V                        A AS G     
Sbjct: 446 KQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTET 505

Query: 129 LSTRSLRLEAEG-----DFDVAD--LRELEREVLQVGEMIDNMEMKVNVPRWTVQARQAA 181
           L  R   LEAEG     D  V +  +RELE +V ++ +  +N E    V    + A Q  
Sbjct: 506 LRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKEN-EKDTEVLMSALSAMQDK 564

Query: 182 GAELLSTVSA 191
              L +++SA
Sbjct: 565 TQHLENSLSA 574


>gi|46047467 hypothetical protein LOC389084 [Homo sapiens]
          Length = 121

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 2/49 (4%)

Query: 188 TVSAGPSSVVSLQ--ERGGGCDPRKALAAILFGAVLLAAVALAVCVAKL 234
           TV+ GP    + +  ++GGG     A+AAI+  A+L   V LA+ V  L
Sbjct: 67  TVAPGPEDSTAQERLDQGGGSLGPGAIAAIVIAALLATCVVLALVVVAL 115


>gi|117938266 hypothetical protein LOC91828 [Homo sapiens]
          Length = 722

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 94  RRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELERE 153
           R+AL  G A   H+   P V +GV    S  A+   ++  L+ EAEG   VADL   ER+
Sbjct: 88  RQALNDGPATG-HSQATPEVPSGVMNGVSQQASTGAASEELKPEAEGK-SVADL-ITERQ 144

Query: 154 VLQVGEMIDNME 165
           +L   E +  +E
Sbjct: 145 LLAAFEQLLRLE 156


>gi|21389533 BTB (POZ) domain containing 14A [Homo sapiens]
          Length = 587

 Score = 28.5 bits (62), Expect = 5.2
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 17/109 (15%)

Query: 55  CARLTAVLRDRGLAADERAEFERLWVAFSGC----------LDLLEADMRRALELGAAFP 104
           C   TAV+ D G  ++ ++   +L  A +            + LL      A+EL  A P
Sbjct: 128 CDSQTAVIEDAG--SEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMELPPAGP 185

Query: 105 LHAPRRPL---VRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLREL 150
             AP+RPL    R GVA A+   AA A  T  L+L     + V  L  L
Sbjct: 186 GLAPKRPLETGPRDGVAVAAG--AAVAAGTAPLKLPRVSYYGVPSLATL 232


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 34/148 (22%), Positives = 60/148 (40%), Gaps = 15/148 (10%)

Query: 38   QELQKTRQK-AQELAVSTCARLTAVLRDRGLAADERAEFERLWVAFSGCL-------DLL 89
            +E+Q T QK   E   +TC  L   + D     DE  E ER W A+   L       +  
Sbjct: 1001 REMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECR 1060

Query: 90   EADMRRALELGAAFPLHAPR-----RPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDV 144
              +++R L+        A +     R +V   V    + + A   + +  +L+AE   D 
Sbjct: 1061 VRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSD- 1119

Query: 145  ADLRELEREVLQVGEMIDNMEMKVNVPR 172
              L +LE++   +     +++ K+   R
Sbjct: 1120 -KLNDLEKKHAMLEMNARSLQQKLETER 1146


>gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens]
          Length = 651

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 26/155 (16%)

Query: 101 AAFPLHAPRRPLVRTGVAGASSGVAAR--ALSTRSLRLEAEGDFDVADLRELEREVLQVG 158
           A  P   P+R    T   GA +GV  +  A  ++ LR++A+      +  +L   +    
Sbjct: 348 AGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDP----EFSDLNSAITYRI 403

Query: 159 EMIDNMEMKVNVPRWTVQARQA----AGAELLSTVSAGPSSVV-----SLQE---RGGGC 206
               +  M+  V   T    QA    A  E  +TV++G ++ V     S QE    GGG 
Sbjct: 404 TNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTGGGP 463

Query: 207 DPRK--------ALAAILFGAVLLAAVALAVCVAK 233
              K        AL  +L   +LLA + LAV V K
Sbjct: 464 SEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHK 498


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
           sapiens]
          Length = 1367

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 4/79 (5%)

Query: 90  EADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRE 149
           EA+ R+  E      +  PR    R  V      VA   +S+RS    A   +++ D  E
Sbjct: 715 EAEYRKVFENFLHNSIFVPRPERKRRDVMQ----VANTTMSSRSRNTTAADTYNITDPEE 770

Query: 150 LEREVLQVGEMIDNMEMKV 168
           LE E       +DN E  V
Sbjct: 771 LETEYPFFESRVDNKERTV 789


>gi|31377607 mitochondrial fission factor [Homo sapiens]
          Length = 342

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 11/85 (12%)

Query: 81  AFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEG 140
           A+   LD+L+ + R  L  G+A     P    VR G++   + +                
Sbjct: 238 AYQQILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDTTIEG-----------TSD 286

Query: 141 DFDVADLRELEREVLQVGEMIDNME 165
           D  V D   L R+++++   +  +E
Sbjct: 287 DLTVVDAASLRRQIIKLNRRLQLLE 311


>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 810

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 13/83 (15%)

Query: 114 RTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRW 173
           R G      G++ R L TR LR+ AE  F+V+         L+ G+++ N      + R 
Sbjct: 44  RVGKLAKDLGLSVRELPTRKLRVSAEDYFNVS---------LESGDLLVN----GRIDRE 90

Query: 174 TVQARQAAGAELLSTVSAGPSSV 196
            +  R+   A    TV+  P +V
Sbjct: 91  KICGRKLECALEFETVAENPMNV 113


>gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]
          Length = 222

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 17/54 (31%), Positives = 29/54 (53%)

Query: 83  SGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRL 136
           +G L +L A ++ +  +G  +P   PR PL +  +  A+SG+    L + SL L
Sbjct: 123 AGLLAVLWAGLQCSGGVGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGSASLLL 176


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 13/83 (15%)

Query: 114 RTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRW 173
           R G      G++ R L TR LR+ AE  F+V+         L+ G+++ N      + R 
Sbjct: 44  RVGKLAKDLGLSVRELPTRKLRVSAEDYFNVS---------LESGDLLVN----GRIDRE 90

Query: 174 TVQARQAAGAELLSTVSAGPSSV 196
            +  R+   A    TV+  P +V
Sbjct: 91  KICGRKLECALEFETVAENPMNV 113


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.131    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,284,927
Number of Sequences: 37866
Number of extensions: 265151
Number of successful extensions: 1007
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1003
Number of HSP's gapped (non-prelim): 19
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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