BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] (1125 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 2333 0.0 gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 2320 0.0 gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 2281 0.0 gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 672 0.0 gi|160707881 formin 2 [Homo sapiens] 122 1e-27 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 122 2e-27 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 114 4e-25 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 107 5e-23 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 104 5e-22 gi|47132519 Ras association and pleckstrin homology domains 1 is... 103 7e-22 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 103 7e-22 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 102 2e-21 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 102 2e-21 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 102 2e-21 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 102 2e-21 gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 98 5e-20 gi|146134388 YLP motif containing 1 [Homo sapiens] 97 9e-20 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 1e-19 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 97 1e-19 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 97 1e-19 gi|163965366 nascent polypeptide-associated complex alpha subuni... 97 1e-19 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 96 1e-19 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 96 1e-19 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 96 1e-19 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 96 2e-19 gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 94 9e-19 gi|150170670 piccolo isoform 2 [Homo sapiens] 91 5e-18 gi|150378539 piccolo isoform 1 [Homo sapiens] 91 5e-18 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 91 5e-18 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 91 6e-18 >gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo sapiens] Length = 1125 Score = 2333 bits (6047), Expect = 0.0 Identities = 1125/1125 (100%), Positives = 1125/1125 (100%) Query: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 Query: 121 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 180 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL Sbjct: 121 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 180 Query: 181 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 240 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ Sbjct: 181 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 240 Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA Sbjct: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 Query: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP Sbjct: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 Query: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC Sbjct: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 Query: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 480 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE Sbjct: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 480 Query: 481 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 540 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI Sbjct: 481 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 540 Query: 541 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 600 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT Sbjct: 541 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 600 Query: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 660 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK Sbjct: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 660 Query: 661 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP Sbjct: 661 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 Query: 721 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV 780 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV Sbjct: 721 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV 780 Query: 781 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 840 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP Sbjct: 781 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 840 Query: 841 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP 900 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP Sbjct: 841 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP 900 Query: 901 GLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 GLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ Sbjct: 901 GLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 Query: 961 FRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDR 1020 FRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDR Sbjct: 961 FRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDR 1020 Query: 1021 HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGN 1080 HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGN Sbjct: 1021 HRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGN 1080 Query: 1081 VDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR 1125 VDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR Sbjct: 1081 VDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR 1125 >gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo sapiens] Length = 1147 Score = 2320 bits (6011), Expect = 0.0 Identities = 1124/1147 (97%), Positives = 1125/1147 (98%), Gaps = 22/1147 (1%) Query: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 Query: 121 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 180 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL Sbjct: 121 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 180 Query: 181 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 240 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ Sbjct: 181 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 240 Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA Sbjct: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 Query: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP Sbjct: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 Query: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC Sbjct: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 Query: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 480 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE Sbjct: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 480 Query: 481 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 540 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI Sbjct: 481 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 540 Query: 541 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 600 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT Sbjct: 541 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 600 Query: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 660 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK Sbjct: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 660 Query: 661 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP Sbjct: 661 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 Query: 721 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN--------------- 765 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN Sbjct: 721 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLS 780 Query: 766 -------LVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 818 +VSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI Sbjct: 781 IGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 840 Query: 819 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 878 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP Sbjct: 841 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 900 Query: 879 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 938 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ Sbjct: 901 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 960 Query: 939 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN 998 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN Sbjct: 961 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN 1020 Query: 999 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK 1058 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK Sbjct: 1021 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK 1080 Query: 1059 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG 1118 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG Sbjct: 1081 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG 1140 Query: 1119 SAAEAPR 1125 SAAEAPR Sbjct: 1141 SAAEAPR 1147 >gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo sapiens] Length = 1132 Score = 2281 bits (5910), Expect = 0.0 Identities = 1109/1147 (96%), Positives = 1110/1147 (96%), Gaps = 37/1147 (3%) Query: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIK CKPEYKV Sbjct: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIK---------------CKPEYKV 45 Query: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN Sbjct: 46 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 105 Query: 121 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 180 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL Sbjct: 106 GVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQL 165 Query: 181 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 240 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ Sbjct: 166 PSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQ 225 Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA Sbjct: 226 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 285 Query: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP Sbjct: 286 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 345 Query: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC Sbjct: 346 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 405 Query: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 480 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE Sbjct: 406 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQE 465 Query: 481 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 540 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI Sbjct: 466 RRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMI 525 Query: 541 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 600 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT Sbjct: 526 PPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVT 585 Query: 601 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 660 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK Sbjct: 586 YIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK 645 Query: 661 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP Sbjct: 646 PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 705 Query: 721 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN--------------- 765 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN Sbjct: 706 PPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLS 765 Query: 766 -------LVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 818 +VSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI Sbjct: 766 IGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 825 Query: 819 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 878 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP Sbjct: 826 GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 885 Query: 879 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 938 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ Sbjct: 886 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 945 Query: 939 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN 998 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN Sbjct: 946 QQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRN 1005 Query: 999 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK 1058 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK Sbjct: 1006 DDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEK 1065 Query: 1059 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG 1118 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG Sbjct: 1066 PEVTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSG 1125 Query: 1119 SAAEAPR 1125 SAAEAPR Sbjct: 1126 SAAEAPR 1132 >gi|62460633 RNA-binding motif protein 16 [Homo sapiens] Length = 1271 Score = 672 bits (1734), Expect = 0.0 Identities = 496/1275 (38%), Positives = 645/1275 (50%), Gaps = 277/1275 (21%) Query: 1 MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKV 60 M+AV FN EL+SL D KPPIS+AKM ITKAAIKAIK YKHVVQ VEKFI+KCKPEYKV Sbjct: 1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKV 60 Query: 61 PGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKN 120 PGLYVIDSIVRQSRHQFG +KDVF PRFS NI +TFQ LY CP +DKSKIVRVLNLWQKN Sbjct: 61 PGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKN 120 Query: 121 GVFKIEIIQPLLDMAAG------TSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSV 174 VFK EIIQPLLDMAAG T A ++N G+P PV ++ Q P+ Sbjct: 121 NVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGTPVTPVTPANV--VQGLPD-- 176 Query: 175 PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQ-QPPKPQSP---ALDNAVMAQVQAI 230 P V Q+ ++D AAVAQ+ Q+ QGQQLQQ++QT Q Q KPQ ALD ++ Q+QA+ Sbjct: 177 PWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQAL 236 Query: 231 TAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP 290 TAQL T + P EQ +F+KKL+DRFD+ ++ E EE KKE Sbjct: 237 TAQL----TAAAAAANTLTPLEQGVSFNKKLMDRFDFGEDSEHSEEPKKE---------- 282 Query: 291 AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350 +PA+ + S + F + +QQ QN++ + +++ QQ Sbjct: 283 -----------IPASQL-SHVSESVNNSIFHQIAEQLQQ------QNLEHLRQQLLEQQQ 324 Query: 351 DPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408 Q P + Q FG +P Q + P V Q Q+ + + Sbjct: 325 P----QKATPQDSQEGTFGSEHSASPSQGSSQQHFLEPE--VNLDDSIDIQQQDMDIDEG 378 Query: 409 PHQQEMEVEQPCIQEVKRHMSDNR-KSRSRSASRSPKRRRSRSGSRSRRSRHR-RSRSRS 466 E EV + QE K+ +R ++ SRS SRSP++RRSRS S SR+ +HR RSRSRS Sbjct: 379 QDGVEEEVFE---QEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRS 435 Query: 467 RDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVAS 526 R+R+R S RS S ERR RE+E+ER++KGLP ++ +T SVCSTTLWVGQ+DK+ TQQD+ + Sbjct: 436 RERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTN 495 Query: 527 LLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIK 586 L EEFG IESINMIPPRGCAY+ MVHRQDA+RALQKLS G+YK+ K IKIAWALNKG+K Sbjct: 496 LFEEFGQIESINMIPPRGCAYVCMVHRQDAFRALQKLSSGSYKIGSKVIKIAWALNKGVK 555 Query: 587 ADYKQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGI-PKKPENEVAQNG 645 +YKQ+WDV+LGVTYIPW+KVK ++LE F EGGM+D +T+N +W+ + +P E Q Sbjct: 556 TEYKQFWDVDLGVTYIPWEKVKVDDLEGFAEGGMIDQETVNTEWETVKSSEPVKETVQT- 614 Query: 646 GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705 T+ +P+ K V P P+ + Q+P P P V +L PPAF + Sbjct: 615 ------TQSPTPVEKETVVTTQAEVFPPPVAM--LQIPV-APAVPTV-SLVPPAFPVSMP 664 Query: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765 +PPPGF P PPPPFLR FNP PPGF+PP PPP+ PP +IPP + P+ Sbjct: 665 VPPPGFS-----PIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVPTSLVQPS 719 Query: 766 LVS--------GARGNAESGDSV--KMYGSAVPPAAPTNLPT------------------ 797 L G G SV + SA+P N PT Sbjct: 720 LSMTPETVKDVGFGSLVIPGGSVASNLATSALPAGNVFNAPTKQAEPEEKVPHLIDHQIS 779 Query: 798 ------------------------PPVTQPVSLLGTQ-----------GVAPGPV----- 817 P VT +LG Q GV P V Sbjct: 780 SGENTRSVIPNDISSNAAILGGQPPNVTSNSGILGVQRPNVSSNSEILGVRPSNVSSSSG 839 Query: 818 ---------------IGLQAP----STGLLGARP-------GLIPLQRP-----PGM--- 843 +G+Q P S+GLLG P GL+ +Q P PG+ Sbjct: 840 IIAAQPPNILNNSGILGIQPPSVSNSSGLLGVLPPNIPNNSGLVGVQPPNVPNTPGLLGT 899 Query: 844 -PP------PHL----QRFPLMPPRPMPPHMMHRGPPPG--------PGGFAMPPPHGM- 883 PP P L QR P MP + P ++ + P P P +PPP + Sbjct: 900 QPPAGPQNLPPLSIPNQRMPTMPMLDIRPGLIPQAPGPRFPLIQPGIPPQRGIPPPSVLD 959 Query: 884 -------KGPFP-------PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQP 929 +GPFP P PF+ PG P P D QQ + + P Sbjct: 960 SALHPPPRGPFPPGDIFSQPERPFLAPGRQSVDNVTNPEKRIPLGNDNIQQEGDRDYRFP 1019 Query: 930 QPQAPQQPQQQQQQQPPPSQ------QPPPTQQQPQQFRNDNRQQFNSGRDQ-------- 975 + ++ +PPP +P ++ P + D R F GR Sbjct: 1020 PIET-----RESISRPPPVDVRDVVGRPIDPREGPGRPPLDGRDHF--GRPPVDIRENLV 1072 Query: 976 ----ERFGRRS-FGNRVENDRERYGNRNDDRDNSNRDRREWG------------------ 1012 + GRR FG N + +G+R D + +R +G Sbjct: 1073 RPGIDHLGRRDHFG---FNPEKPWGHRGDFDEREHRVLPVYGGPKGLHEERGRFRSGNYR 1129 Query: 1013 --------RRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR-GKEKPEVTD 1063 R ++ HRD ++R R R R+RD RD + RE R G+++ + Sbjct: 1130 FDPRSGPWNRGFGQEVHRDFDDRRR--PWERQRDRDDRDFDFCREMNGNRLGRDRIQ--- 1184 Query: 1064 RAGGNKTVEPPISQV 1078 N V PP ++V Sbjct: 1185 ----NTWVPPPHARV 1195 Score = 39.7 bits (91), Expect = 0.016 Identities = 47/201 (23%), Positives = 77/201 (38%), Gaps = 20/201 (9%) Query: 926 QQQPQPQAPQQPQQQ---QQQQPPPSQQPPPTQQ---QPQQFRNDN----RQQFNSGRDQ 975 QQQPQ PQ Q+ + PSQ +QQ +P+ +D+ +Q + Q Sbjct: 322 QQQPQKATPQDSQEGTFGSEHSASPSQGS--SQQHFLEPEVNLDDSIDIQQQDMDIDEGQ 379 Query: 976 ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1035 + F + R +R R S R+ RRS R R + R R S R Sbjct: 380 DGVEEEVFEQEAKKVAVRSRSRTHSRSRSRSPRK---RRSRSRSGSRKRKHRKRSRSRSR 436 Query: 1036 DRERD-----SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASELEKG 1090 +R+R S +R +R ++E + K P + + + + QV T +L Sbjct: 437 ERKRKSSRSYSSERRAREREKERQKKGLPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNL 496 Query: 1091 VSEAAVLKPSEELPAEATSSV 1111 E ++ +P + V Sbjct: 497 FEEFGQIESINMIPPRGCAYV 517 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 122 bits (307), Expect = 1e-27 Identities = 119/343 (34%), Positives = 144/343 (41%), Gaps = 68/343 (19%) Query: 654 PVSPIPKPLPVPVPPIPVPAPIT---VPPPQVPPHQ---PGPPVVGA-LQPPAFTPPLGI 706 P + IP P P+P IP+P P+ +PPP P P PP+ GA + PP P GI Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008 Query: 707 PPPGF--GPGVPPPPP------PPPFLRPGFNPMHLPPGFLPPG---PPPPITPPVSIPP 755 PPP G G+PPPPP PPP PG +PP PG PPPP P IPP Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPP 1065 Query: 756 PHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAP---TNLPTPPVTQPVSLLGTQGV 812 P PP+ A + G+ +PP P +P PP P+ +G Sbjct: 1066 P--PPLP----------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGVGIPPP 1110 Query: 813 APGPVIGLQAPSTGLLGARPGLIPLQRPPGM---PPPHLQRFPLMPPRPM-------PPH 862 P P G+ P L GA G+ P PG PPP L R + PP P+ PP Sbjct: 1111 PPLPGAGIPPPPP-LPGA--GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167 Query: 863 MMHRG--PPPGPGGFAMPPPHGMKG---PFPPHGP---FVRPGGMPGLG-GPGPGPGGPE 913 + G PPP G +PPP + G P PP P P +PG+G P P P P Sbjct: 1168 LPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227 Query: 914 DRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ---QPPP 953 G PP P P P PQ P P PPP Sbjct: 1228 PGTGIPPPPLLPVSGP----PLLPQVGSSTLPTPQVCGFLPPP 1266 Score = 110 bits (274), Expect = 1e-23 Identities = 115/348 (33%), Positives = 134/348 (38%), Gaps = 59/348 (16%) Query: 649 TSHTEPVSPIPKPLPV------PVPPIPVPAPITVPPPQVPPHQ--PGPPVVGALQPPAF 700 T T P + IP+P P+ P PP P+P PPP +P P PP+ GA PP Sbjct: 887 TVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPP-- 944 Query: 701 TPPLGIPPPGFGPGVPPPPP--------PPPFLRPGF-NPMHLPPGFLPPG--------P 743 PPP G +PPPPP PPP G P LP +PP P Sbjct: 945 ------PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998 Query: 744 PPPITPPVSIPPPHTPP---ISIPNLVSGARGNAESGDSVKMYGSAVPPAAP---TNLPT 797 PPP P IPPP P I P + G A + G+ +PP P +P Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPGAGIPP 1054 Query: 798 PPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGM---PPPHLQRFPLM 854 PP P+ G P P G+ P L GA G+ P PG PPP L + Sbjct: 1055 PP---PLPGAGIPPPPPLPGAGIPPPPP-LPGA--GIPPPPPLPGAGIPPPPPLPGVGIP 1108 Query: 855 PPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPED 914 PP P+P + PPP PG PPP PP P R G P PG G P Sbjct: 1109 PPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167 Query: 915 RDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP----PPTQQQP 958 G PP P P P P PPP P PP P Sbjct: 1168 LPGAGIPP--PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213 Score = 102 bits (255), Expect = 2e-21 Identities = 117/364 (32%), Positives = 135/364 (37%), Gaps = 85/364 (23%) Query: 648 ETSHTEPVSP-------IPKPLPVP-------------VPPIPVPAP-ITVPP------P 680 +TSH VS IP P P+P VPP P P P +TVP P Sbjct: 838 QTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIP 897 Query: 681 QVPPHQ-------PGPPVVGA-LQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPM 732 Q PP Q P PP+ GA + PP P GI P PG PPPPP Sbjct: 898 QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP---------- 947 Query: 733 HLPPGFLPPGPP--------PPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG 784 LP +PP PP PP P IPPP PP+ A + G Sbjct: 948 -LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP--PPLP----------GAGIPPPPPLPG 994 Query: 785 SAVPPAAP---TNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPP 841 + +PP P +P PP P+ G P P G+ P L GA G+ P P Sbjct: 995 AGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPP-LPGA--GIPPPPPLP 1048 Query: 842 GM---PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG 898 G PPP L + PP P+P + PPP PG PPP PP P G Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107 Query: 899 MPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP----PPT 954 P PG G P G PP P P P P + PPP P PP Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP 1165 Query: 955 QQQP 958 P Sbjct: 1166 PPLP 1169 Score = 98.2 bits (243), Expect = 4e-20 Identities = 86/260 (33%), Positives = 104/260 (40%), Gaps = 46/260 (17%) Query: 632 GIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPIT---VPPPQVPPHQ-- 686 GIP P G P + IP P P+P IP P P+ +PPP P Sbjct: 1040 GIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096 Query: 687 -PGPPVVGA-LQPPAFTPPLGIPPPGF--GPGVPPP--------PPPPPFLRPGFNPMHL 734 P PP+ G + PP P GIPPP G G+PPP PPPPP R G P Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156 Query: 735 PPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTN 794 PG P PPPP+ PPP P + IP + G +PP P Sbjct: 1157 LPGAGIP-PPPPLPGAGIPPPPPLPGVGIP-------------PPPPLPGVGIPPPPP-- 1200 Query: 795 LPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLM 854 LP + P L G G+ P P L P TG+ P L+P+ PP +P P Sbjct: 1201 LPGAGIPPPPPLPG-MGIPPAPAPPLPPPGTGI--PPPPLLPVSGPPLLPQVGSSTLP-- 1255 Query: 855 PPRPMPPHMMHRGPPPGPGG 874 P + PPP P G Sbjct: 1256 -----TPQVCGFLPPPLPSG 1270 Score = 79.0 bits (193), Expect = 2e-14 Identities = 74/240 (30%), Positives = 95/240 (39%), Gaps = 71/240 (29%) Query: 632 GIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP----VPPIPVPAPITVPPPQVPPH-- 685 GIP P G P + IP P P+P PP P+P PPP +P Sbjct: 1117 GIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173 Query: 686 QPGPPVVGA-LQPPAFTPPLGIPPPGF--GPGVPPPPPPPPFLRPGFNPMHLPPGFLPPG 742 P PP+ G + PP P +GIPPP G G+PPPPP LP +PP Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-------------LPGMGIPPA 1220 Query: 743 PPPPITPP-VSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVT 801 P PP+ PP IPPP P+S P L +P + LPTP V Sbjct: 1221 PAPPLPPPGTGIPPPPLLPVSGPPL--------------------LPQVGSSTLPTPQVC 1260 Query: 802 QPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPP 861 G P P+ +GL G + + + G ++ P+ P RPM P Sbjct: 1261 ---------GFLPPPL------PSGLFG-----LGMNQDKGS-----RKQPIEPCRPMKP 1295 Score = 51.6 bits (122), Expect = 4e-06 Identities = 37/116 (31%), Positives = 44/116 (37%), Gaps = 12/116 (10%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPF-------GFPGDGMQQPAYTQHQNM 338 P A +PP P P P A PPPP P PG G+ P + Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129 Query: 339 DQFQPRM-MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 P GI P +V +PP +PG G+ P PP P P PP P V P Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185 Score = 51.6 bits (122), Expect = 4e-06 Identities = 35/109 (32%), Positives = 43/109 (39%), Gaps = 9/109 (8%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPR- 344 P A +PP P P P A PPPP PG G+ P + P Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLP 1147 Query: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 +GI P +PP +PG G+ P PP P + P PP P V P Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP 1196 Score = 50.8 bits (120), Expect = 7e-06 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 13/116 (11%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPF-------GFPGDGMQQPAYTQHQNM 338 P A +PP P P P A PPPP P PG G+ P + Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173 Query: 339 DQFQPRM-MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 P +GI P V +PP +PG G+ P PP P M P P PP+ P Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP-APAPPLPPP 1228 Score = 49.7 bits (117), Expect = 2e-05 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 9/109 (8%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRM 345 P A +PP P P P A PPPP PG G+ P + P Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLP 1059 Query: 346 -MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 GI P +PP +PG G+ P PP P P PP P V P Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1108 Score = 48.9 bits (115), Expect = 3e-05 Identities = 34/111 (30%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPFG-------FPGDGMQQPAYTQHQNM 338 P A +PP P +P P A PPPP P PG G+ P + Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975 Query: 339 DQFQPRM-MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 P GI P +PP +PG G+ P PP P P PP P Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026 Score = 48.1 bits (113), Expect = 5e-05 Identities = 34/104 (32%), Positives = 41/104 (39%), Gaps = 9/104 (8%) Query: 294 VPPAPTATVPAAAA-PAAASPPPPQAPFG-------FPGDGMQQPAYTQHQNMDQFQPRM 345 +PP P A +P P AA PPPP P PG G+ P + P Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993 Query: 346 -MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 GI P +PP +PG G+ P PP P P PP P Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037 Score = 46.6 bits (109), Expect = 1e-04 Identities = 66/259 (25%), Positives = 87/259 (33%), Gaps = 35/259 (13%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDA--FAAVAQLFQTTQGQQLQ----QILQT 207 SP V + PP P P P S F + L + + +Q Q Q+ Sbjct: 747 SPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQS 806 Query: 208 FQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDY 267 QPP P S L +A Q + +T Q S + + +AF Sbjct: 807 ISQPPPPPS-LLWSAGQGQPGSQPPHSISTEFQTSHEHSV------SSAFKNSC--NIPS 857 Query: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPP-------PQAPF 320 E S + P PP P TVP + A PPP P P Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPP----PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913 Query: 321 GFPGDGMQQPAYTQHQNMDQFQPRM-MGIQQDPMHHQVPLPPNGQMPGFGL-----LP-- 372 PG G+ P + P GI P +PP +PG G+ LP Sbjct: 914 PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973 Query: 373 -TPPFPPMAQPVIPPTPPV 390 PP PP+ IPP PP+ Sbjct: 974 GIPPPPPLPGAGIPPPPPL 992 Score = 45.8 bits (107), Expect = 2e-04 Identities = 37/113 (32%), Positives = 44/113 (38%), Gaps = 14/113 (12%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRM 345 P A +PP P P P A PPPP PG G+ P + P Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPGVGIPPPPPLP 1191 Query: 346 -MGIQQDPMHHQVPLPPNGQMPGFGL--LPTPPFPPMAQPVIPPTP--PVQQP 393 +GI P +PP +PG G+ P PP PP IPP P PV P Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG-IPPPPLLPVSGP 1243 Score = 41.2 bits (95), Expect = 0.006 Identities = 63/285 (22%), Positives = 96/285 (33%), Gaps = 58/285 (20%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQ--- 210 S PP + E + ++V PQ S V + Q +QQ+ QT + Sbjct: 629 SKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRT 688 Query: 211 ---PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDY 267 + Q PALD V + Q L+ T + E+K ++L Sbjct: 689 KIAELERQYPALDTEVASGHQG----LENGVTASGDVCLEALRLEEKEVRHHRIL----- 739 Query: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAP------------------- 308 E ++++ S E+ V T P +P P A + P Sbjct: 740 --EAKSIQTSPTEEG-GVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISV 796 Query: 309 ---------AAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQ--V 357 + + PPPP + G G Q + H +FQ + + Sbjct: 797 QLDSHQPTQSISQPPPPPSLLWSAGQG-QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI 855 Query: 358 PLPP-------NGQMPGFGLLPTPP--FPPMAQPVIPPTPPVQQP 393 P PP + MPG G++P PP P M P +P T Q P Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP 900 Score = 41.2 bits (95), Expect = 0.006 Identities = 36/113 (31%), Positives = 42/113 (37%), Gaps = 23/113 (20%) Query: 290 PAAAVPPAP----TATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRM 345 P A +PP P P P PPPP PG G+ P + P Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP----LPGVGIPPPPPLPGAGIPPPPPLP 1213 Query: 346 -MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIP-------PTPPV 390 MGI P PLPP PG G+ P P P P++P PTP V Sbjct: 1214 GMGIPPAPAP---PLPP----PGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259 Score = 40.4 bits (93), Expect = 0.010 Identities = 50/185 (27%), Positives = 63/185 (34%), Gaps = 18/185 (9%) Query: 786 AVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGL-QAP-STGLLGARPGLIPLQRPPGM 843 A PAAP PT QP + LG GP G +AP S A L L Sbjct: 229 AEEPAAP---PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAA 285 Query: 844 PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLG 903 P R P PP P + P A P PFP GP G P G Sbjct: 286 EP----REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRG 341 Query: 904 GPGPGPGGPED--------RDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQ 955 G ED G + P+ + PQ + ++P+++ Q P+ P Sbjct: 342 AGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQ-RLGEEPEEEAQGPDAPAAASLPGS 400 Query: 956 QQPQQ 960 P Q Sbjct: 401 PAPSQ 405 Score = 33.1 bits (74), Expect = 1.5 Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Query: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP--PPTQQQPQ 959 QQ + QQQ Q Q QQQQQQQ +++P PPT PQ Sbjct: 200 QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQ 242 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 122 bits (306), Expect = 2e-27 Identities = 108/356 (30%), Positives = 134/356 (37%), Gaps = 61/356 (17%) Query: 649 TSHTEPVSPIPKPLPVPVPPIPV-------PAPITVPPPQVPPHQPGPPVVGALQPPAFT 701 T H E P P P P+ PP P+ P+ I PPPQ PP PP+ G PP Sbjct: 555 TPHLE-TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP--L 611 Query: 702 PPLGIPPPGFGPGVPPPP---PPPPFLRPGFNPMHLPPGFLP----------PGPPPPIT 748 PL PPP P + PP PP P P +P+ P P P PPP + Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP-S 670 Query: 749 PPVSIP--PPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL 806 PPV P PP +PP+S A +++ S+ VPP+ P + P P P Sbjct: 671 PPVQAPFSPPASPPVS-----PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP--- 722 Query: 807 LGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLM----PPRPMPPH 862 Q P LQ P + A P + P PP PP L PL PP +P Sbjct: 723 -PPQAPPPLAAPPLQVPPSP--PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS 779 Query: 863 MMHRGPPPGPGGFAMPPPHGMKGP---FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG-R 918 + + PP P A PP + P FP PF +P P P P Sbjct: 780 PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839 Query: 919 QQPPQQPQQQPQPQAPQQPQQQQQQ----------------QPPPSQQPPPTQQQP 958 Q P P P QAP++P PPPS+ P T P Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895 Score = 90.9 bits (224), Expect = 6e-18 Identities = 106/384 (27%), Positives = 137/384 (35%), Gaps = 85/384 (22%) Query: 609 PEELESFCEGGMLDSDTLNPDWKGIPKKP-ENEVAQNGGAETSHTEPVSP-IPKPLPVPV 666 P L S L S TL + P + + + + + T P SP + PL +P Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465 Query: 667 -PPI---------PVPAPITVPPPQ----VPPHQPGPPVVGALQPPAFTPPLGIPPPGFG 712 PP+ P+ +P+T+ P Q + H P P+ + PP T PP Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525 Query: 713 PGVPPPPPP--------PPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIP 764 P PP PP L+ P+ P PP P P P+ PP P++ P Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC---PLQAPPS---PLTTP 579 Query: 765 NLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPS 824 PP P+++ TPP P +L A P+ GL +P Sbjct: 580 -----------------------PPETPSSIATPPPQAPPAL------ASPPLQGLPSPP 610 Query: 825 TGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGP-----PPGPGGFAMPP 879 L PL PP PP L PL P P PP P P P A+ Sbjct: 611 ---------LSPLATPPPQAPPXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAV-- 658 Query: 880 PHGMKGPF-PPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQ--QPQQQPQPQAPQQ 936 H ++ PF PP P V+ P P P P Q PP P Q P P Sbjct: 659 -HLLQAPFSPPPSPPVQAPFSP----PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713 Query: 937 PQQQQQQQPPPSQQPPPTQQQPQQ 960 P PPP Q PPP P Q Sbjct: 714 PPMSPSATPPP-QAPPPLAAPPLQ 736 Score = 86.3 bits (212), Expect = 2e-16 Identities = 108/410 (26%), Positives = 130/410 (31%), Gaps = 110/410 (26%) Query: 646 GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLG 705 G + P PLP +PP P P+ P P PP PP + L P TPP Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSP---PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367 Query: 706 IPPPGFGPGVPPPP-----PP--------PPFLRPGFNPMHLP----------------- 735 PP P + PP PP P L+ +P+ L Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427 Query: 736 -------------------PGFLPPGPPP---PITPPVSIP-----PPHTPPISIP---N 765 P PP PP P++ P S P P P+S P + Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487 Query: 766 LVSGARGNAESGDSVKMYGSAVPP------AAPTNLPTPP--VTQPVSLLGTQGVAPGPV 817 + A + +PP AP +L TPP +T P L +AP P+ Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP-PLENLPSLAPPPL 546 Query: 818 IGLQAPSTG---LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGG 874 AP T P PLQ PP PL P P P + PP P Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPS---------PLTTPPPETPSSIATPPPQAPPA 597 Query: 875 FAMPPPHGMKGPFPPHGPFVRPG-------GMPGLGGPGPGPGGPE----DRDGRQQP-- 921 A PP G+ P PP P P +P L P P P Q P Sbjct: 598 LASPPLQGL--PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655 Query: 922 --------PQQPQQQPQPQAPQQPQQQQQQQP---PPSQQPPPTQQQPQQ 960 P P P QAP P P PPSQ PP P Q Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705 Score = 80.1 bits (196), Expect = 1e-14 Identities = 87/305 (28%), Positives = 109/305 (35%), Gaps = 48/305 (15%) Query: 637 PENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP-QVPPHQPGPPVVGAL 695 P ++ + A P P P+ P P P PP QVPP P P + Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS-- 748 Query: 696 QPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPP 755 P+ TPP +PP P + PP PP L +P+ PP P PP TPP+ P Sbjct: 749 --PSATPPPRVPPLLAAPPLQVPPSPPASL--PMSPLAKPP---PQAPPALATPPLQALP 801 Query: 756 PHTPPISIPNLVSGARGNAESGDSVKMYGSAV---PPAAPTNLPTPPVTQPVSLLGTQGV 812 +PP S P G A S + S + PP AP L P + P S + + Sbjct: 802 --SPPASFP-------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852 Query: 813 APGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMH------- 865 P T + G R L PP PPP + + H Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTLSGPDLAGHSSSATSTPEE 910 Query: 866 -RGPPPGP--GGFAMPPPHG----------MKGPFPPHGPFVRPGGMPGLGGPGPGPGGP 912 RG GP G A PPP +GP PP + G PG P P GP Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP----LAFRGAPGAPLPWPPATGP 966 Query: 913 EDRDG 917 DG Sbjct: 967 GSADG 971 Score = 65.9 bits (159), Expect = 2e-10 Identities = 75/293 (25%), Positives = 102/293 (34%), Gaps = 49/293 (16%) Query: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVP-APITVPPPQVPPHQPGPPVV 692 P P + P+ P P PP +P +P+ PPPQ PP PP+ Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 693 GALQPPA-------FTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPP 745 PPA F+P +P P PPP PP L P+ P P P Sbjct: 799 ALPSPPASFPGQAPFSPSASLP---MSPLATPPPQAPPVLAA---PLLQVP------PSP 846 Query: 746 PITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS 805 P +P ++ P PP P+ + SG + + + PP P+ P+ ++ P Sbjct: 847 PASP--TLQAPRRPPTPGPD-------TSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-D 896 Query: 806 LLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR----PMPP 861 L G A L+ +G P PPP + P P PP Sbjct: 897 LAGHSSSATSTPEELRGYDSG---------PEGGAAASPPPDAELAACHPAAWSRGPAPP 947 Query: 862 HMMHRGPP----PGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPG 910 + RG P P P G+ + GP PG PGP PG Sbjct: 948 -LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP-ESATPAPGALDPGPSPG 998 Score = 54.7 bits (130), Expect = 5e-07 Identities = 78/374 (20%), Positives = 123/374 (32%), Gaps = 92/374 (24%) Query: 132 LDMAAGTSNAAPVAENVTNNEGSPPPPVKVS-SEPPTQATPN--SVPAV--------PQL 180 L +A + +A P + + + +PP S + PP QA P+ ++P + P L Sbjct: 341 LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400 Query: 181 PSSDAFAAVAQL----------------FQTTQGQQLQQILQTFQQPPK----------- 213 + + A++ L F T +Q Q L + +P Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460 Query: 214 ---PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDE 270 P SP L ++ V +++ L P Q A+ P ++ L+ Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET-QSSLA 519 Query: 271 PEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA----------------AAPAAASPP 314 P +++ TT P+ A PP TA+ P A P+ + P Sbjct: 520 PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579 Query: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP-- 372 PP+ P Q P P + G+ P+ + PP P L P Sbjct: 580 PPETPSSIATPPPQAPPALA-------SPPLQGLPSPPL-SPLATPPPQAPPXLALPPLQ 631 Query: 373 TPPFPPMAQPVI------------------------PPTPPVQQPFQASFQAQNEPLTQK 408 PP PP + P+ PP+PPVQ PF P Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691 Query: 409 PHQQEMEVEQPCIQ 422 P Q + P +Q Sbjct: 692 PSQAPPSLAAPPLQ 705 Score = 52.0 bits (123), Expect = 3e-06 Identities = 76/316 (24%), Positives = 103/316 (32%), Gaps = 66/316 (20%) Query: 156 PPPVKVSSEP---------------PTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQ 200 PPP++ +S P P QA P+ + P S Q Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602 Query: 201 LQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSE---QKAAFPPPEQKTAF 257 LQ + P P SP A L+ P+ P+ A P P+ A Sbjct: 603 LQGL------PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656 Query: 258 DKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASP---- 313 LL + P ++ +P A+ P +P+AT P+ A P+ A+P Sbjct: 657 AVHLLQA-PFSPPPSPPVQAP---------FSPPASPPVSPSATPPSQAPPSLAAPPLQV 706 Query: 314 ---------------PPPQAPFGFPGDGMQ----QPAYTQHQNMDQFQPRMMGIQQDPMH 354 PPPQAP +Q PA PR+ + P Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP-P 765 Query: 355 HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIP----PTPPV----QQPFQASFQAQNEPLT 406 QVP P +P L PP P A P P+PP Q PF S PL Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825 Query: 407 QKPHQQEMEVEQPCIQ 422 P Q + P +Q Sbjct: 826 TPPPQAPPVLAAPLLQ 841 Score = 44.3 bits (103), Expect = 7e-04 Identities = 91/370 (24%), Positives = 108/370 (29%), Gaps = 108/370 (29%) Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPPP--PPFLR-----------------PGFNPMHL 734 A P A P L P P PG P PPPP P LR G + Sbjct: 14 ARTPAARAPGLLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 735 PPGFLPPGPP---------PPITPPVS-----IPPPHTP---PISIPNLVSG-------- 769 P GP P PP S PP P+S P SG Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130 Query: 770 ------------ARGNAESGD--SVKMYGSAVPPAAPT-NLPTPPVTQPVSLLGTQGVAP 814 ARG A S G+ + PT P+P + + GT+ P Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190 Query: 815 GPVIG------LQAPSTGLLGA------RPGLIPLQRPP---GMPPPHLQRF-----PLM 854 P + P + A P +RP G+ P + PL Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250 Query: 855 PPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGG------PGPG 908 P P RG P P + P P G++ PP R P LG P Sbjct: 251 SPARSGPSA--RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 909 PGGPEDRD-----------GRQQPPQQPQQQPQPQAPQQPQQQQQQQ-------PPPSQQ 950 P G + R PP P P P AP P Q PPSQ Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368 Query: 951 PPPTQQQPQQ 960 PP P Q Sbjct: 369 PPSMTTPPMQ 378 Score = 43.9 bits (102), Expect = 9e-04 Identities = 65/292 (22%), Positives = 86/292 (29%), Gaps = 49/292 (16%) Query: 130 PLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAV 189 P L + + P++ + T +PPP + PP Q P+ + P PS+ V Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPP----LAAPPLQVPPSPPASPPMSPSATPPPRV 757 Query: 190 AQLFQTTQGQQLQQILQTFQQPPK--PQSPALDNAVMAQVQAITAQLKTTPTQPSE---- 243 L LQ PP P SP A T L+ P+ P+ Sbjct: 758 PPLLAAPP-------LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810 Query: 244 -----------QKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAA 292 A PPP+ LL P A + T AP Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQ---VPPSPPA----------SPTLQAPRR 857 Query: 293 AVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQP-RMMGIQQD 351 P P +V A +P PP P P + P H + P + G Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917 Query: 352 PMHHQVPLPPNG------QMPGFGLLPTPPFPPMAQPVIP-PTPPVQQPFQA 396 P PP + P PP P P P PP P A Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969 Score = 36.6 bits (83), Expect = 0.14 Identities = 67/297 (22%), Positives = 100/297 (33%), Gaps = 31/297 (10%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLP--------SSDAF 186 +AGTS+ P + + G PP K +S P + + P S++ Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141 Query: 187 AAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQL-----KTTPTQP 241 A + + + L + P P +P+ A ++ L P P Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201 Query: 242 SE--QKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPT 299 +E +K+ E T R S+ ++A ++PA + P A Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-R 260 Query: 300 ATVPAAAAPAAASPPPPQA---PFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQ 356 T A A P+ P QA P P PA + P G + P Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP---- 316 Query: 357 VPLPPNGQMPGFGLLPT--PPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 409 VP P N P LP PP PP+A P+ PP+P Q P +Q P Sbjct: 317 VPPPDNAATP----LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369 Score = 35.4 bits (80), Expect = 0.31 Identities = 58/285 (20%), Positives = 93/285 (32%), Gaps = 69/285 (24%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQ 194 +AG P + +++++ P + S P + TP + PA P P A+ Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPAR--SGPSARGTPRA-PAHPSQPKPKGLQAL----- 280 Query: 195 TTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQK 254 +PP+ P D A + +++ TP+ + PPP+ Sbjct: 281 ---------------RPPQVTPPRKDAA--PALGPLSSSPLATPSPSGTKARPVPPPDNA 323 Query: 255 TAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPP 314 P + S T P PP+P+A P+ + P Sbjct: 324 AT------------PLPATLPPSPPLAT-------PLPLAPPSPSAPPSLQTLPSPPATP 364 Query: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTP 374 P QAP MQ P P + I + H + P L P Sbjct: 365 PSQAPPSMTTPPMQAP------------PSLQTIPPIQVPHSLTSPS---------LQAP 403 Query: 375 PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQP 419 P P+A + T + P + QA + LT P Q + + P Sbjct: 404 P-SPLALSSLQATTSLGSP---TLQATHSFLTMSPRQTQASLTSP 444 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 114 bits (286), Expect = 4e-25 Identities = 122/376 (32%), Positives = 139/376 (36%), Gaps = 72/376 (19%) Query: 634 PKKPENEVAQNG----GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPP-------PQV 682 P KP+ Q G G +P P P+ P P P P PP P+ Sbjct: 54 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113 Query: 683 PPHQP-GPPVVGALQPPAFTPPLGIP--PPGFGPGVP--PPPP-----PPP--------F 724 PP +P GPP G QP PP G P PP G P PPPP PPP Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173 Query: 725 LRPGFNPMHLPP--GFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKM 782 P P PP G P GPPPP P PP P +G GD+ K Sbjct: 174 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN-KS 232 Query: 783 YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG 842 + PP P P QP QG P P P G +P G Sbjct: 233 QSARSPPGKPQGPPPQGGNQP------QGPPPPPGKPQGPPPQGG----------NKPQG 276 Query: 843 MPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGL 902 PPP + P PP+ R PP P G PPP G P P P +P G P Sbjct: 277 PPPPGKPQGP--PPQGGSKSRSSRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPPQ 331 Query: 903 GG------PGPG-PGGPEDRDG-----RQQPPQQPQQQPQ-----PQAPQQPQ--QQQQQ 943 GG P PG P GP + G + PP +PQ PQ PQ P P QQ Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391 Query: 944 QPPPSQQPPPTQQQPQ 959 Q PP+ QP + PQ Sbjct: 392 QAPPAGQPQGPPRPPQ 407 Score = 109 bits (272), Expect = 2e-23 Identities = 120/350 (34%), Positives = 131/350 (37%), Gaps = 50/350 (14%) Query: 642 AQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFT 701 AQN + S E S I P PP P PP P GPP G QP Sbjct: 16 AQNLNEDVSQEESPSLIAGN-PQGAPPQGGNKP--QGPPSPPGKPQGPPPQGGNQPQGPP 72 Query: 702 PPLGIP---PPGFG--PGVPPPP-----PPP-------PFLRPGFNPMHLPP--GFLPPG 742 PP G P PP G P PPPP PPP P PG P PP G P G Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG-KPQGPPPQGGNQPQG 131 Query: 743 PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802 PPPP P PP P +G GD+ K S PP P P Q Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN-KSRSSRSPPGKPQGPPPQGGNQ 190 Query: 803 PVSLLGTQGVAPGPVIGLQAPSTGLLGARP-GLIPLQRPPGMPPP-----HLQRFPLMPP 856 P QG P P P G G +P G P +P G PP R P P Sbjct: 191 P------QGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242 Query: 857 RPMPPH--MMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGG--------PG 906 + PP +GPPP PG PPP G P P P +P G P GG P Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGGSKSRSSRSPP 301 Query: 907 PGPGGPEDRDGRQ-QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQ 955 P GP + G Q Q P P +PQ PQ + Q PP Q PP Q Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351 Score = 89.7 bits (221), Expect = 1e-17 Identities = 97/291 (33%), Positives = 106/291 (36%), Gaps = 62/291 (21%) Query: 680 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP--G 737 PQ P Q G G PP P G PP G G P PPPP PG P PP G Sbjct: 36 PQGAPPQGGNKPQGPPSPPG--KPQGPPPQG---GNQPQGPPPP---PG-KPQGPPPQGG 86 Query: 738 FLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPT 797 P GPPPP P PPP GD + S PP P P Sbjct: 87 NKPQGPPPPGKPQG--PPPQ-------------------GDKSRSPRS--PPGKPQGPPP 123 Query: 798 PPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP-GLIPLQRPPGMPPP-----HLQRF 851 QP QG P P P G G +P G P +P G PP R Sbjct: 124 QGGNQP------QGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGDNKSRSSRS 175 Query: 852 PLMPPRPMPPH--MMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP-GPG 908 P P+ PP +GPPP PG PPP G +P G P G P GP Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN----------KPQGPPPPGKPQGPP 225 Query: 909 PGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 P G + PP +PQ P PQ QPQ P PP +PQ Sbjct: 226 PQGDNKSQSARSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275 Score = 72.0 bits (175), Expect = 3e-12 Identities = 72/220 (32%), Positives = 86/220 (39%), Gaps = 30/220 (13%) Query: 764 PNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAP 823 P+L++G A K G PP P P QP QG P P P Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQP------QGPPPPPGKPQGPP 82 Query: 824 STGLLGARP-GLIPLQRPPGMPPP-HLQRFPLMPP-RPMPPHMMHRGPPPGPGGFAMPPP 880 G G +P G P +P G PP R P PP +P P P GP PPP Sbjct: 83 PQG--GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP----PPP 136 Query: 881 HGMKGPFPPHGPFVRPGGMPGLGGP-GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ- 938 +GP P G +P G P G P GP P G + PP +PQ P PQ QPQ Sbjct: 137 GKPQGPPPQGGN--KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP-PQGGNQPQG 193 Query: 939 ----QQQQQQPP------PSQQPPPTQQQPQQFRNDNRQQ 968 + Q PP P PPP + Q + DN+ Q Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ 233 Score = 63.2 bits (152), Expect = 1e-09 Identities = 55/163 (33%), Positives = 66/163 (40%), Gaps = 31/163 (19%) Query: 821 QAPSTGLLGARPGLIPLQ---RPPGMPPPHLQRFPLMPPRPMPPH-MMHRGPPPGPGGFA 876 Q S L+ P P Q +P G P P P P P P +GPPP PG Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSP-----PGKPQGPPPQGGNQPQGPPPPPGKPQ 79 Query: 877 MPPPHGMKGPFPPHGPFVRPGGMPGLGGP-GPGPGGPEDRDGRQQPPQQPQQQP-----Q 930 PPP G +P G P G P GP P G + R R PP +PQ P Q Sbjct: 80 GPPPQGGN----------KPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPPQGGNQ 128 Query: 931 PQAPQQPQQQQQQQPP-----PSQQPPPTQQQPQQFRNDNRQQ 968 PQ P P + Q PP P PPP + Q + DN+ + Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171 Score = 48.5 bits (114), Expect = 3e-05 Identities = 61/263 (23%), Positives = 73/263 (27%), Gaps = 55/263 (20%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P + +G PPPP K PP P P P QG Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP----------PQGDNKS 232 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 Q ++ P KPQ P Q P K PPP K Sbjct: 233 QSARS--PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ------ 284 Query: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 322 P+ +S+ + + P P P PPPP P G Sbjct: 285 -----GPPPQGGSKSRS-----------SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 328 Query: 323 PGDGMQQPAYTQHQNMDQFQPRMMGI----------------QQDPMHHQVPLPPNGQMP 366 P G +P Q P G QQ+ + Q P PP G P Sbjct: 329 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388 Query: 367 GFGLLPTPPFPPMAQPVIPPTPP 389 P PP QP PP PP Sbjct: 389 -----QQPQAPPAGQPQGPPRPP 406 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/251 (22%), Positives = 70/251 (27%), Gaps = 35/251 (13%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P + +G PPPP K PP P P P QG Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP----------PQGDNKS 170 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 + ++ P KPQ P Q P K PPP K Sbjct: 171 RSSRS--PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP------- 221 Query: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 322 P ++K + A + P P P PPPP P G Sbjct: 222 ------QGPPPQGDNKSQS---------ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266 Query: 323 PGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 382 P G +P Q P G + P P G P G P P PP +P Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGG-SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325 Query: 383 VIPPTPPVQQP 393 PP +P Sbjct: 326 QGPPPQGGNKP 336 Score = 45.8 bits (107), Expect = 2e-04 Identities = 61/263 (23%), Positives = 78/263 (29%), Gaps = 22/263 (8%) Query: 134 MAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQAT-PNSVPAVPQLPSSDAFAAVAQL 192 + AG AP + +G P PP K PP P P P P Q Sbjct: 31 LIAGNPQGAP-PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP----PQG 85 Query: 193 FQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPE 252 QG P KPQ P ++ + + P Q Q PPP Sbjct: 86 GNKPQGP---------PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136 Query: 253 QKTAFDKKLLDRFDYDDEPEAVEES--KKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAA 310 K P + + D + ++ +P P P P Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP----PGKPQGPPPQGGNQPQ 192 Query: 311 ASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGL 370 PPPP P G P G +P Q P G + P P G P G Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-GPPPQGDNKSQSARSPPGKPQGPPPQGGN 251 Query: 371 LPTPPFPPMAQPVIPPTPPVQQP 393 P P PP +P PP +P Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKP 274 Score = 38.5 bits (88), Expect = 0.036 Identities = 39/159 (24%), Positives = 49/159 (30%), Gaps = 22/159 (13%) Query: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMH 354 P P P PPPP P G P G +P Q P + P Sbjct: 54 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-- 111 Query: 355 HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEM 414 P P G P G P P PP +P PP Q + Q P KP Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-------QGGNKPQGPPPPGKPQGPPP 164 Query: 415 EVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSR 453 + DN+ SRS P+ + G++ Sbjct: 165 Q-------------GDNKSRSSRSPPGKPQGPPPQGGNQ 190 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 107 bits (268), Expect = 5e-23 Identities = 92/271 (33%), Positives = 107/271 (39%), Gaps = 39/271 (14%) Query: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPIT 748 PP +G Q P+G P GP P PPPPP + P PP PP PPP Sbjct: 35 PPGMGLNQNRG---PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHP 91 Query: 749 PP-VSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL 807 P PP P S +V+ G A S S+ PPA P PP Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP-------- 143 Query: 808 GTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR----PMPPHM 863 G PGP P + A PG P P P P PP+ P PP Sbjct: 144 ---GSGPGPT---PTPPPAVTSAPPGAPP-------PTPPSSGVPTTPPQAGGPPPPPAA 190 Query: 864 MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG-----PGPGGPEDRDGR 918 + P PGPG P P G KG P GP +PGG PGL PG P GG E R GR Sbjct: 191 V---PGPGPGPKQGPGPGGPKGGKMPGGP--KPGGGPGLSTPGGHPKPPHRGGGEPRGGR 245 Query: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 949 Q P QQ Q P P + +++ S+ Sbjct: 246 QHHPPYHQQHHQGPPPGGPGGRSEEKISDSE 276 Score = 78.2 bits (191), Expect = 4e-14 Identities = 76/244 (31%), Positives = 89/244 (36%), Gaps = 26/244 (10%) Query: 638 ENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 697 +N G S +P P P P P P P PPP PP P P P Sbjct: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101 Query: 698 PA--FTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPP 755 P + P+ PG PGV PP P P P PGP P P V+ P Sbjct: 102 PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161 Query: 756 PHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPG 815 P PP + P+ SG + PP P +P P QG PG Sbjct: 162 PGAPPPTPPS----------SGVPTTPPQAGGPPPPPAAVPGPGPGP------KQGPGPG 205 Query: 816 PVIGLQAPSTGLLGARPGLIPLQRPPGMP-PPHL-QRFPLMPPRPMPPH--MMHRGPPP- 870 G + P G PG L P G P PPH P + PP+ H+GPPP Sbjct: 206 GPKGGKMPGGPKPGGGPG---LSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262 Query: 871 GPGG 874 GPGG Sbjct: 263 GPGG 266 Score = 60.1 bits (144), Expect = 1e-08 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 6/118 (5%) Query: 836 PLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 895 P +PP P PH Q+ P PP+ ++ +GP P PG + PP P P Sbjct: 83 PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP-----P 137 Query: 896 PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 953 G P GPGP P P P P P P P Q PPP+ P P Sbjct: 138 TSGAPPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194 Score = 59.3 bits (142), Expect = 2e-08 Identities = 44/99 (44%), Positives = 46/99 (46%), Gaps = 14/99 (14%) Query: 866 RGPPPGPGG---FAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPP 922 RG G GG F PPP GM G GP G PG GP P P +QQPP Sbjct: 19 RGGGGGRGGLHDFRSPPP-GM-GLNQNRGPM---GPGPGQSGPKPPIPPPPPHQQQQQPP 73 Query: 923 QQ---PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 Q PQQ P Q P PQ QQQQPPP PP +P Sbjct: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPP---PPQDSSKP 109 Score = 52.0 bits (123), Expect = 3e-06 Identities = 35/87 (40%), Positives = 40/87 (45%), Gaps = 12/87 (13%) Query: 891 GPFVRPGGMPGLGG------PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 944 G F R GG G GG P PG G ++R P Q P+P P P QQQQQ Sbjct: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQQQQ 71 Query: 945 PPPS----QQPPPTQQQPQQFRNDNRQ 967 PPP QQPPP Q P + +Q Sbjct: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQ 98 Score = 50.4 bits (119), Expect = 9e-06 Identities = 62/258 (24%), Positives = 79/258 (30%), Gaps = 62/258 (24%) Query: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP 214 PPPP + +PP Q P P Q P Q Q Q PP P Sbjct: 62 PPPPHQQQQQPPPQQPPPQQPPPHQPPPHP------------------QPHQQQQPPPPP 103 Query: 215 QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAV 274 Q + V+AQ + + P S A PP P Sbjct: 104 QDSS--KPVVAQGPGPAPGVGSAPPASSSAPPATPPTS----------------GAPPGS 145 Query: 275 EESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQ 334 T+AP A PP P ++ P A PPPP A PG G +Q Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ----- 200 Query: 335 HQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPF 394 P G + M P G PG G P ++ P P PP + Sbjct: 201 -------GPGPGGPKGGKM-------PGGPKPGGG-------PGLSTPGGHPKPPHRGGG 239 Query: 395 QASFQAQNEPLTQKPHQQ 412 + Q+ P + H Q Sbjct: 240 EPRGGRQHHPPYHQQHHQ 257 Score = 43.5 bits (101), Expect = 0.001 Identities = 49/154 (31%), Positives = 54/154 (35%), Gaps = 20/154 (12%) Query: 637 PENEVAQNGGAETSHTEPVS-PIPKPLPVPV-----PPIPVPAPITVPPPQVPPHQPGPP 690 P + A TS P S P P P P P P P P P + P PP GPP Sbjct: 126 PASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185 Query: 691 VVGALQP-----PAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP---GFLPPG 742 A P P P G P G PG P P P PG +P PP G P G Sbjct: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK--PPHRGGGEPRG 243 Query: 743 ----PPPPITPPVSIPPPHTPPISIPNLVSGARG 772 PP PPP P +S + G Sbjct: 244 GRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEG 277 Score = 33.1 bits (74), Expect = 1.5 Identities = 30/112 (26%), Positives = 34/112 (30%), Gaps = 24/112 (21%) Query: 288 TAPAAAVPPAPT---ATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPR 344 + P +PP P P P PPP Q P P HQ P Sbjct: 54 SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP----------PHPQPHQQQQPPPP- 102 Query: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPT---PPVQQP 393 P P+ G P G+ PP A P PPT PP P Sbjct: 103 -------PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147 Score = 32.0 bits (71), Expect = 3.4 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 8/77 (10%) Query: 343 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402 P MG+ Q+ + P+ P G P PP PP PP QQP Sbjct: 35 PPGMGLNQN----RGPMGPGPGQSG----PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ 86 Query: 403 EPLTQKPHQQEMEVEQP 419 P +PHQQ+ P Sbjct: 87 PPPHPQPHQQQQPPPPP 103 Score = 31.6 bits (70), Expect = 4.4 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 14/75 (18%) Query: 355 HQVPLPPNGQMPGFGLL----PTPPFPPMA--QPVIPPTPPVQQ----PFQASFQAQNEP 404 H PP PG GL P P P + +P IPP PP QQ P Q Q P Sbjct: 29 HDFRSPP----PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP 84 Query: 405 LTQKPHQQEMEVEQP 419 PH Q + +QP Sbjct: 85 HQPPPHPQPHQQQQP 99 Score = 31.2 bits (69), Expect = 5.8 Identities = 36/161 (22%), Positives = 62/161 (38%), Gaps = 28/161 (17%) Query: 929 PQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVE 988 P+ A + P Q++++ PP T F + Q++ S + E+ R ++ Sbjct: 460 PEKLAQKNPMYQKERETPPRFAQHGT------FEYEYSQRWKSLDEMEKQQREQVEKNMK 513 Query: 989 NDRERYGNRNDD---RDNSNRDRREWGRRSPDRDRHRDL----------------EERNR 1029 + +++ + +D +N R++ RR + R +L EER R Sbjct: 514 DAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRR 573 Query: 1030 RSSGH--RDRERDSRDRESRREKEEARGKEKPEVTD-RAGG 1067 R R RE + + R R E G P D R GG Sbjct: 574 REEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGG 614 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 104 bits (259), Expect = 5e-22 Identities = 151/656 (23%), Positives = 234/656 (35%), Gaps = 145/656 (22%) Query: 372 PTPPFPPMAQPVIPP-----TPPVQQPFQASFQAQNEPLTQKPHQQ------EMEVEQPC 420 P P ++ P +PP PP + + ++ T ++ E++ + Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKA 520 Query: 421 IQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRR-SRHRRSRSRSRDRRRHSPRSRSQ 479 + E +S ++++ + + K ++ R +++S+++ ++ + S Sbjct: 521 VHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580 Query: 480 ERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINM 539 +++ + K P + E C + +KR D IN Sbjct: 581 SNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE---EKRQLSLD-------------INK 624 Query: 540 IPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIK----------IAWALNKGIKADY 589 +P +V + Q +L+ + +++ +++K + L K K Sbjct: 625 LPGEKLGRVVHII-QSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 683 Query: 590 KQYWDVELGVTYIPWDKVKPEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAET 649 ++ DV G + + E ES E DS+ + KK + + Sbjct: 684 EKV-DVIAGSSKMKG--FSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740 Query: 650 SHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPP 709 H + + P P+P PP PPQ PP P PP QPP PP +P Sbjct: 741 HHHQQMQQAPAPVPQQPPP----------PPQQPP--PPPPPQQQQQPPPPPPPPSMPQQ 788 Query: 710 GFGPGVPPPPPP-----PPFLRPG-----FNP--------MHLPPGFLPPGPPPPITPPV 751 P + PPP P L P F+P +HLP LPP P P P Sbjct: 789 A-APAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQP---PE 844 Query: 752 SIPPPH-------TPPI---SIPNLVSGARGNAESGDSVKMYGSAVPPAAPTN--LPTPP 799 PPH +PP ++P S A + AV PA LP PP Sbjct: 845 HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPP 904 Query: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPM 859 + QP +L P P P T + + LQ+ LQ+ + PP P+ Sbjct: 905 MAQPPQVLLEDEEPPAP------PLTSMQMQ----LYLQQ--------LQK--VQPPTPL 944 Query: 860 PPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQ 919 P + + PP P +PPP PH P L P P P+ Sbjct: 945 LPSVKVQSQPPPP----LPPP--------PH-----PSVQQQLQQQPPPPPPPQP----- 982 Query: 920 QPPQQPQQQPQP--------------QAPQQPQQQQQQQPPPSQQPPPTQ-QQPQQ 960 QPP Q Q QP P Q P PQ QQ PPP QQPPP Q +PQQ Sbjct: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038 Score = 76.6 bits (187), Expect = 1e-13 Identities = 95/403 (23%), Positives = 151/403 (37%), Gaps = 66/403 (16%) Query: 661 PLPVPVPPIP-VPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPP 719 P P+P PP P V + PP PP QP PP QPP P+ + P F + PP Sbjct: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP--RPVHLQPMQFSTHIQQPP 1012 Query: 720 PPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDS 779 PP G P H PPG PP PP P P I H+P R + S Sbjct: 1013 PPQ-----GQQPPHPPPGQQPP-PPQPAKPQQVIQHHHSP-----------RHHKSDPYS 1055 Query: 780 VKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGA---RPGLIP 836 G +P + +P ++Q SL P +Q L A +P + Sbjct: 1056 T---GHLREAPSPLMIHSPQMSQFQSLTHQSP----PQQNVQPKKQELRAASVVQPQPLV 1108 Query: 837 LQRPPGMPPPHLQRFPLMPP-RPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 895 + + + P ++ P P RP PP + P +P MK P P +R Sbjct: 1109 VVKEEKIHSPIIRSEPFSPSLRPEPP----KHPESIKAPVHLPQRPEMK-PVDVGRPVIR 1163 Query: 896 PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPS-----QQ 950 P P P PG P + +Q+ +P+ P P++ + + S Q+ Sbjct: 1164 P---PEQNAPPPGA------------PDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQK 1208 Query: 951 PPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRRE 1010 P T + +D+ +QF RR+ + E ++ R R+E Sbjct: 1209 HPTTPSSTAKSSSDSFEQF----------RRAAREKEEREKALKAQAEHAEKEKERLRQE 1258 Query: 1011 WGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEA 1053 R D D + + +++++ R + ++++++A Sbjct: 1259 RMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQA 1301 Score = 62.8 bits (151), Expect = 2e-09 Identities = 71/282 (25%), Positives = 98/282 (34%), Gaps = 54/282 (19%) Query: 155 PPPPVKVSSEPPTQATPNSVP---------------------AVPQLPSSDAFAAVAQLF 193 PPPP + +PP P S+P PQLP S F + Sbjct: 766 PPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS-VFDPIGHFT 824 Query: 194 QTTQGQQLQQILQTFQQPPKPQSPA-LDNAVMAQVQAITAQLKTTPTQPSEQKAAFPP-P 251 Q ++ QPP+ +P L+ + A+ L P++PS + AA PP P Sbjct: 825 QPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKP 884 Query: 252 EQKTAF-----DKKLLDRFDYDDEPEAVEESKKEDTTAVTT------TAPAAAVPPAPTA 300 + A LL + P+ + E ++ +T+ V P PT Sbjct: 885 ARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP-PTP 943 Query: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQ------PAYTQHQNMDQFQPRMMGIQQDPM- 353 +P+ + PP P P +QQ P Q Q QP + PM Sbjct: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQ 1003 Query: 354 ---HHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQ 392 H Q P PP GQ PP PP Q PP P Q Sbjct: 1004 FSTHIQQPPPPQGQQ--------PPHPPPGQQPPPPQPAKPQ 1037 Score = 50.8 bits (120), Expect = 7e-06 Identities = 53/200 (26%), Positives = 66/200 (33%), Gaps = 43/200 (21%) Query: 619 GMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPI-TV 677 G ++ T P +P + + PV P P P P + V P+ TV Sbjct: 182 GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241 Query: 678 PPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPG 737 PPQ PL PPP VPP P PPP P P+ P Sbjct: 242 VPPQ---------------------PLQTPPP-----VPPQPQPPP--APAPQPVQSHPP 273 Query: 738 FLPPGPPP-----------PITPPVSIPPPHTPPISIPNLVSGARG-NAESGDSVKMYGS 785 + P P T P +I P H PP P + G ES VK Sbjct: 274 IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK 333 Query: 786 AVPPAAPTNLPTPPVTQPVS 805 VP + P P + VS Sbjct: 334 DVPDS--QQHPAPEKSSKVS 351 Score = 48.9 bits (115), Expect = 3e-05 Identities = 93/452 (20%), Positives = 152/452 (33%), Gaps = 123/452 (27%) Query: 144 VAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQ 203 V+ +T P PP+ ++PP + P P L S + QL + L Sbjct: 890 VSPALTQTPLLPQPPM---AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP 946 Query: 204 ILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLD 263 ++ QPP P P +V Q+Q Q P P Q PPP+Q+ Sbjct: 947 SVKVQSQPPPPLPPPPHPSVQQQLQ----QQPPPPPPPQPQ----PPPQQQ--------- 989 Query: 264 RFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFP 323 + P V + +T + PP P P P PPP A P Sbjct: 990 ---HQPPPRPVHLQPMQFSTHIQQ-------PPPPQGQQPPHPPPGQQPPPPQPAK---P 1036 Query: 324 GDGMQQPAYTQHQNMDQF---------------QPRMMGIQQDPMHHQVPLPPNGQMPGF 368 +Q +H D + P+M Q + HQ P N Q Sbjct: 1037 QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQS--LTHQSPPQQNVQPKKQ 1094 Query: 369 GL-----------------------LPTPPFPPMAQPVIPPTP-----PVQQPFQASFQA 400 L + + PF P +P P P PV P + + Sbjct: 1095 ELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP 1154 Query: 401 QN--EPLTQKPHQ------------QEMEVEQPCIQE--------------VKRH----- 427 + P+ + P Q Q+ E + P + V++H Sbjct: 1155 VDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPS 1214 Query: 428 -----MSDNRKSRSRSASRSPKRRRSRSG----SRSRRSRHRRSRSRSR---DRRRHSPR 475 SD+ + R+A +R ++ + + R R+ R RSR D + R Sbjct: 1215 STAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARR 1274 Query: 476 SRSQERRDREKERERRQKGLPQVKPETASVCS 507 + + RR +E+++++RQ+ Q + + A+V + Sbjct: 1275 AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAA 1306 Score = 48.5 bits (114), Expect = 3e-05 Identities = 61/212 (28%), Positives = 78/212 (36%), Gaps = 42/212 (19%) Query: 755 PPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAP 814 P I I RG E+G + K S VP T TPP TQ T P Sbjct: 165 PTEETEIMIVQAKGRGRGRKETG-TAKPGVSTVPNT--TQASTPPQTQ------TPQPNP 215 Query: 815 GPVIGLQAPSTGLLGARPGLIPLQRP--PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 872 PV QA P LI +Q P +PP LQ P +PP+P PP P P P Sbjct: 216 PPV---QATPHPFPAVTPDLI-VQTPVMTVVPPQPLQTPPPVPPQPQPP------PAPAP 265 Query: 873 GGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG----PGPGGPEDRDGRQQPPQQPQQQ 928 P H P + P G P D +PP P Sbjct: 266 ------------QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLP--- 310 Query: 929 PQPQAPQQPQQQQQQQP--PPSQQPPPTQQQP 958 P+P+ + Q+++ +P PP + P +QQ P Sbjct: 311 PEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342 Score = 40.8 bits (94), Expect = 0.007 Identities = 37/142 (26%), Positives = 50/142 (35%), Gaps = 18/142 (12%) Query: 295 PPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMH 354 PP P ++P AAPA S PPP P Q P + + F ++ + Q + Sbjct: 778 PPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPG-SVFDPIGHFTQPILHLPQPELP 836 Query: 355 HQVPLPPNGQMPG-------------FGLLPTPPFPP----MAQPVIPPTPPVQQPFQAS 397 +P PP P LP P P A P P PP P Sbjct: 837 PHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQ 896 Query: 398 FQAQNEPLTQKPHQQEMEVEQP 419 +P +P Q +E E+P Sbjct: 897 TPLLPQPPMAQPPQVLLEDEEP 918 Score = 36.6 bits (83), Expect = 0.14 Identities = 20/74 (27%), Positives = 34/74 (45%) Query: 915 RDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRD 974 R ++ ++ +QQ Q + QQ QQQQQ + P Q Q D +++ R+ Sbjct: 1273 RRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKRE 1332 Query: 975 QERFGRRSFGNRVE 988 QER R + ++ Sbjct: 1333 QERRRREAMAATID 1346 Score = 35.8 bits (81), Expect = 0.23 Identities = 93/481 (19%), Positives = 148/481 (30%), Gaps = 113/481 (23%) Query: 91 NITATFQYLYLCPSEDKSKIVRVLN--LWQKNGVFKIEIIQPLLDMAAG-------TSNA 141 N T Y+Y P +D + L QK E + ++ A G T A Sbjct: 130 NTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTA 189 Query: 142 APVAENVTNNEGSPPPPVKVSSEP---PTQATPNSVPAV-PQLPSSDAFAAVAQLFQTTQ 197 P V N + PP + +P P QATP+ PAV P L V Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP------ 243 Query: 198 GQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAF 257 Q LQT PP P P A Q P Q A P KT Sbjct: 244 ----PQPLQT--PPPVPPQPQPPPAPAPQ-----------PVQSHPPIIAATPQPVKTKK 286 Query: 258 DKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQ 317 K +K DTT TT P P P S P + Sbjct: 287 GVK-----------------RKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVK 329 Query: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQD-----------PMHHQVPLPPNGQMP 366 P D Q PA + + + GI ++ P + V + G Sbjct: 330 PPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHD 389 Query: 367 GFGLLPTP---------------------------------PFPPMAQPVIPPTPPVQQP 393 ++ P + P V+ +Q Sbjct: 390 YCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDV 449 Query: 394 FQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSR 453 F+ F + +P + + V P + + ++ S S S S S + Sbjct: 450 FEMRF----AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEE 505 Query: 454 SRRSR-----------HRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPET 502 R R H + + S+ +++ P+ + +++++++KE+ +R++ + + K Sbjct: 506 ERAQRLAELQEQLKAVHEQLAALSQP-QQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSK 564 Query: 503 A 503 A Sbjct: 565 A 565 Score = 35.0 bits (79), Expect = 0.40 Identities = 38/132 (28%), Positives = 48/132 (36%), Gaps = 23/132 (17%) Query: 289 APAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQF------- 341 AP PP P P P PPP P P QQ A + F Sbjct: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPPP---PPSMPQQAAPAMKSSPPPFIATQVPV 807 Query: 342 -QPRMMGIQQDPM-HHQVPLPPNGQMPGFGLLPTPPFPP-MAQPVIPPTPP-VQQPFQAS 397 +P++ G DP+ H P+ LP P PP + QP TPP + Q S Sbjct: 808 LEPQLPGSVFDPIGHFTQPILH---------LPQPELPPHLPQPPEHSTPPHLNQHAVVS 858 Query: 398 FQAQNEPLTQKP 409 A + L Q+P Sbjct: 859 PPALHNALPQQP 870 Score = 34.3 bits (77), Expect = 0.68 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 17/91 (18%) Query: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTP 374 P G PG ++ + HQ M Q P+ Q P PP P P Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPA--------PVPQQPPPPPQQ--------PPP 766 Query: 375 PFPP-MAQPVIPPTPPVQQPFQASFQAQNEP 404 P PP Q PP PP P QA+ ++ P Sbjct: 767 PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP 797 Score = 32.3 bits (72), Expect = 2.6 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 9/60 (15%) Query: 652 TEPVSPIPKPLPVPVPPIPVPAPITVPP-PQVPPHQPGPPVVGALQPPAFTPPLGIPPPG 710 +EP SP +P P P P + AP+ +P P++ P G PV+ P PPPG Sbjct: 1122 SEPFSPSLRPEP-PKHPESIKAPVHLPQRPEMKPVDVGRPVIRP-------PEQNAPPPG 1173 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 103 bits (258), Expect = 7e-22 Identities = 107/391 (27%), Positives = 130/391 (33%), Gaps = 82/391 (20%) Query: 649 TSHTEPVSPIPK------------PLPVPVPPIPVPAPITVPPPQVPPHQPGP------- 689 TS P+SP PK PLP P PP P P P PPP P Q P Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662 Query: 690 ------------------------PVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFL 725 P +Q + P + +PP G VPPPPPPPP Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV---VPPPPPPPPPP 719 Query: 726 RPGFNPMHLPPGFLPPG------PPPP-----------ITPPVSIPPPHTPPISIPNLVS 768 PG L P P PPPP + PP PPP P P Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779 Query: 769 GARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ-------PVSLLG-TQGVAPGPVIGL 820 + S K V AAP PTPPV P S + + P PV Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPT-PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPP 838 Query: 821 QAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 880 P A+P PL P + +FP P P PP M + P P A P Sbjct: 839 TLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP---PPPTPPAMESQPLKPVPANVAPQSP 895 Query: 881 HGMKGPFPPHGPFVRPGGMPGLGGPGPG-----PGGPEDRDGRQQPPQQPQQQPQPQAPQ 935 +K P P P P P P P P PP P P P Sbjct: 896 PAVKAK-PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954 Query: 936 QP-QQQQQQQPPPSQQPPPTQQQPQQFRNDN 965 P ++ + P ++PPPT Q+ ++ + Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985 Score = 88.6 bits (218), Expect = 3e-17 Identities = 106/390 (27%), Positives = 135/390 (34%), Gaps = 88/390 (22%) Query: 649 TSHTEPVSPIPKPLPVPVPPIPVPAP-ITVPPP-----------QVPPHQPGPPVVGALQ 696 T P P P P+P P+PP P P +T+P P Q P P PPV A + Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 Query: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSI--- 753 PAF P IPP P PP P PPP L F PP P++P S+ Sbjct: 816 QPAF-PASYIPP---SPPTPPVPVPPPTLPK-------QQSFCAKPPPSPLSPVPSVVKQ 864 Query: 754 -----PPPHTPPISIPNLVSGARGNA--ESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL 806 PPP TPP + N +S +VK P + P P P P S Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924 Query: 807 LGTQGVAPGPVIG-------LQAPSTGLLGARPGLIPLQRPPG--MPPPHLQRFPLM--- 854 L P PV +P+ G+ PG PPP QR + Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984 Query: 855 -------PPRPMPPHMMHRGPPPGPGGF----AMPPPHGMKGPFPPHGPFVRPGGM---- 899 P RP ++ + PP G +PPP P + V G+ Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQG 1044 Query: 900 ------PGLGGPGPG-----PGGPEDRDGRQQPPQQPQQQPQPQAPQ------------- 935 P L G G P P D D PP+ P + P Sbjct: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVV 1104 Query: 936 QPQQQQQQQPPPSQQPPPTQQQPQQFRNDN 965 PQ QQ + + PPPT+ + RND+ Sbjct: 1105 NPQPQQWSKMSVKKAPPPTRPK----RNDS 1130 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/270 (27%), Positives = 97/270 (35%), Gaps = 73/270 (27%) Query: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAA--VAQLF----QTTQGQQLQQILQTF 208 P PP+ PP P P P LPS A +A A +F T+ Q Q Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL 683 Query: 209 QQPPKP---QSPALDNAVMAQVQAIT----------------AQLKTTPTQPSEQKAAFP 249 +PP P QS ++ ++ + AQLK P PS + + P Sbjct: 684 FKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP 743 Query: 250 PPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPA 309 PP K +T AP PP P +PA Sbjct: 744 PPPLKI------------------------HQVQHITQVAPPTPPPPPP---IPA----- 771 Query: 310 AASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFG 369 P PPQAP P + PA T + + + Q P P+PP + P F Sbjct: 772 ---PLPPQAP---PKPLVTIPAPTSTKTV-----APVVTQAAPPTPTPPVPPAKKQPAFP 820 Query: 370 ---LLPTPPFPPMAQPVIPPTPPVQQPFQA 396 + P+PP PP+ PV PPT P QQ F A Sbjct: 821 ASYIPPSPPTPPV--PVPPPTLPKQQSFCA 848 Score = 58.9 bits (141), Expect = 3e-08 Identities = 73/289 (25%), Positives = 97/289 (33%), Gaps = 20/289 (6%) Query: 108 SKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPT 167 S I R+ N Q +G + +P + + P N PPPP PP Sbjct: 668 STITRLQNASQHSGA----LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP------PPP 717 Query: 168 QATPNSVPA----VPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP-QSPALDNA 222 TP S A P PS F+A + Q Q + Q+ PP P +P A Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777 Query: 223 VMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKL-LDRFDYDDEPEAVEESKKED 281 + I A T P +AA P P KK Y Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837 Query: 282 TTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ-PAYTQHQNMDQ 340 T + A PP+P + VP+ A+ PPP P ++ PA Q+ Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897 Query: 341 FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPP 389 + + + P VP P P L PP PP P PP PP Sbjct: 898 VKAKP---KWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943 Score = 54.3 bits (129), Expect = 6e-07 Identities = 70/261 (26%), Positives = 89/261 (34%), Gaps = 36/261 (13%) Query: 146 ENVTNNEGS----PPPPVKVSS--EPPTQATPNSV--PAVPQLPSSDAFAAVAQLFQTTQ 197 +N + + G+ P PPV S +P PN V P P P +A+AQL Sbjct: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC 733 Query: 198 GQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAF 257 L Q F PP P + QVQ IT TP P A PP A Sbjct: 734 APSLPQ----FSAPPPPLK-------IHQVQHITQVAPPTPPPPPPIPAPLPPQ----AP 778 Query: 258 DKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQ 317 K L+ S K VT AP PP P A A + P PP Sbjct: 779 PKPLVTI--------PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT 830 Query: 318 APFGFPGDGM-QQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPF 376 P P + +Q ++ P ++Q + Q P PP P P P Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ--IASQFPPPPT--PPAMESQPLKPV 886 Query: 377 PPMAQPVIPPTPPVQQPFQAS 397 P P PP + +Q S Sbjct: 887 PANVAPQSPPAVKAKPKWQPS 907 Score = 50.4 bits (119), Expect = 9e-06 Identities = 66/284 (23%), Positives = 95/284 (33%), Gaps = 72/284 (25%) Query: 129 QPLLDMAAGTSN--AAPVAENVTNNEGSPP-PPVK------VSSEPPTQATPNSVPAVPQ 179 +PL+ + A TS APV +PP PP K S PP+ TP P Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT 839 Query: 180 LPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPT 239 LP +F A + PP P SP V + V+ I +Q PT Sbjct: 840 LPKQQSFCA--------------------KPPPSPLSP-----VPSVVKQIASQFPPPPT 874 Query: 240 QPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAP--------- 290 P+ + P A P AV+ K +++ +P Sbjct: 875 PPAMESQPLKPVPANVA-----------PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923 Query: 291 AAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPG--------DGMQQPAYTQHQN----- 337 + PP P + VPA P + P G PG G ++P T +N Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983 Query: 338 ---MDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPP 378 + +P+ + D + + P P LP P PP Sbjct: 984 SSGAEHPEPKRPSV--DSLVSKFTPPAESGSPSKETLPPPAAPP 1025 Score = 50.1 bits (118), Expect = 1e-05 Identities = 39/149 (26%), Positives = 54/149 (36%), Gaps = 16/149 (10%) Query: 283 TAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQ 342 T T + P+ +PP P P P PPPP P G P + ++ + + Q Sbjct: 617 TPYTASQPSPPLPPPPPP--PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQ 674 Query: 343 ------------PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPV 390 P +Q + Q+ +PPNG +P P PP P A + P P Sbjct: 675 NASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA 734 Query: 391 QQPFQASFQAQNEPLTQKPHQQEMEVEQP 419 P F A PL Q +V P Sbjct: 735 --PSLPQFSAPPPPLKIHQVQHITQVAPP 761 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 103 bits (258), Expect = 7e-22 Identities = 107/338 (31%), Positives = 122/338 (36%), Gaps = 46/338 (13%) Query: 640 EVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPA 699 +V+Q P P P+ P P P P PPPQ GPP G Q P Sbjct: 22 DVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP- 80 Query: 700 FTPPLGIPP--PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI-TPPVSIPPP 756 PP G P PG P PPP +P P PP P GPPP P PPP Sbjct: 81 --PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPPPQGGNRPQGPPPP 135 Query: 757 HTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGP 816 P +G GD + S PP P P QP QG P P Sbjct: 136 GKP-----------QGPPPQGDKSRSPRS--PPGKPQGPPPQGGNQP------QGPPPPP 176 Query: 817 VIGLQAPSTGLLGARP-GLIPLQRPPGMPPP----HLQRFPLMPPRPMPPH--MMHRGPP 869 P G G +P G P +P G PP + P P+ PP +GPP Sbjct: 177 GKPQGPPPQG--GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP 234 Query: 870 PGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGG--------PGPGPGGPEDRDGRQQP 921 P PG PPP G P P P +P G P GG P P GP ++G Sbjct: 235 PPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293 Query: 922 PQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 P PQ PQ P Q Q PP Q + PQ Sbjct: 294 GPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331 Score = 87.0 bits (214), Expect = 9e-17 Identities = 98/324 (30%), Positives = 113/324 (34%), Gaps = 68/324 (20%) Query: 628 PDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQP 687 P G P+ P + ++ + +P P P+ P P P P PPPQ Sbjct: 71 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130 Query: 688 GPPVVGALQPPAFTPPLG--IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPP 745 GPP G Q P PP G P PG P PPP +P P PP P GPPP Sbjct: 131 GPPPPGKPQGP---PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPPP 184 Query: 746 PITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS 805 PPP P +G GD K S PP P P QP Sbjct: 185 QGGKKPQGPPPPGKP----------QGPPPQGD--KSRSSQSPPGKPQGPPPQGGNQP-- 230 Query: 806 LLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMH 865 QG P P +P G PPP P PP P P Sbjct: 231 ----QGPPPPP---------------------GKPQG-PPPQGGNKPQGPPPPGKP---- 260 Query: 866 RGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQP 925 +GPP G + P P GP + G P GP P GG PQQP Sbjct: 261 QGPPAQGGSKSQ---SARSPPGKPQGPPQQEGNNP--QGPPPPAGG---------NPQQP 306 Query: 926 QQQP--QPQAPQQPQQQQQQQPPP 947 Q P QPQ P +P Q + PP Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSRPP 330 Score = 60.5 bits (145), Expect = 9e-09 Identities = 54/158 (34%), Positives = 63/158 (39%), Gaps = 25/158 (15%) Query: 839 RPPGMPPPHLQRFPLMPPR------PMPPHMMHRGPPPGPGGFAM---PPPHGMKGPFPP 889 +P G PPP + P PP+ P P +GPPP G PPP +GP P Sbjct: 67 KPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 124 Query: 890 HGPFVRPGGMPGLGGP-GPGPGGPEDRDGR------QQPPQQPQQQPQ-----PQAPQQP 937 G RP G P G P GP P G + R R Q PP Q QPQ P PQ P Sbjct: 125 GGN--RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182 Query: 938 QQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQ 975 Q ++P P Q P Q Q G+ Q Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ 220 Score = 50.4 bits (119), Expect = 9e-06 Identities = 39/104 (37%), Positives = 45/104 (43%), Gaps = 22/104 (21%) Query: 866 RGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP-GPGPGGPEDRDGRQQPPQQ 924 +GPPP PG PPP G +P G P G P GP P G + R R PP + Sbjct: 48 QGPPPPPGKPQGPPPQGGN----------KPQGPPPPGKPQGPPPQGDKSRSPRS-PPGK 96 Query: 925 PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQ 968 PQ P PQ Q Q PP PPP + Q + NR Q Sbjct: 97 PQGPP-------PQGGNQPQGPP---PPPGKPQGPPPQGGNRPQ 130 Score = 48.1 bits (113), Expect = 5e-05 Identities = 59/247 (23%), Positives = 72/247 (29%), Gaps = 25/247 (10%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P + +G PPPP K PP P P P QG + + Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP----------PQGDKSR 149 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 P KPQ P Q P +K PPP K Sbjct: 150 S---PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQG 206 Query: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 322 D+ P + P PP P PPPP P G Sbjct: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPGKPQGP 263 Query: 323 PGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 382 P G + +Q +P+ QQ+ + Q P PP G P P PP QP Sbjct: 264 PAQGGSK---SQSARSPPGKPQGPP-QQEGNNPQGPPPPAGGNP-----QQPQAPPAGQP 314 Query: 383 VIPPTPP 389 PP PP Sbjct: 315 QGPPRPP 321 Score = 43.9 bits (102), Expect = 9e-04 Identities = 62/254 (24%), Positives = 76/254 (29%), Gaps = 15/254 (5%) Query: 150 NNEGSPPPPVKVSSEPPT---QATPNSVPAVPQLP---SSDAFAAVAQLFQTTQGQQLQQ 203 N PPPP K PP +P S P PQ P + QG Q Sbjct: 66 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 125 Query: 204 ILQTFQQPP--KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKL 261 + PP KPQ P ++ + + P Q Q PPP K Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185 Query: 262 LDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPA-PTATVPAAAAPAAASPPPPQAPF 320 + P K + + ++ PP P P PPPP P Sbjct: 186 GGKKPQGPPPPG----KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241 Query: 321 GFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMA 380 G P G +P Q P G + P P G G P P PP Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAG 300 Query: 381 -QPVIPPTPPVQQP 393 P P PP QP Sbjct: 301 GNPQQPQAPPAGQP 314 Score = 37.7 bits (86), Expect = 0.062 Identities = 31/118 (26%), Positives = 41/118 (34%), Gaps = 5/118 (4%) Query: 276 ESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQH 335 ++ ED + + + A P P+ P PPPP P G P G +P Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGPS---PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73 Query: 336 QNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 Q P + P P P G P G P P PP +P PP +P Sbjct: 74 PGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 102 bits (255), Expect = 2e-21 Identities = 85/232 (36%), Positives = 98/232 (42%), Gaps = 45/232 (19%) Query: 673 APITVPP--PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFN 730 A ITVPP P P P PP+ G PP P P PPPPPPPP PG Sbjct: 559 AAITVPPSVPSRAPVPPAPPLPG--DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616 Query: 731 PMHLPPGFLPPG----PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSA 786 + PP LP G PPPP++ +IPPP PP+ G S G+A Sbjct: 617 CISSPPS-LPGGTAISPPPPLSGDATIPPP--PPLP--------EGVGIPSPSSLPGGTA 665 Query: 787 VPPAAP----TNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG 842 +PP P +P PP P G+ G+ P P P G G P PL PG Sbjct: 666 IPPPPPLPGSARIPPPPPPLP----GSAGIPPPP-----PPLPGEAGMPPPPPPLPGGPG 716 Query: 843 MPPPHLQRFPLMPPRPMPPHMMHRGPPPGPG-GFAMPPPHGMKGPFPPHGPF 893 +PPP PP P P + PPP PG G PPP G P P PF Sbjct: 717 IPPP--------PPFPGGPGI----PPPPPGMGMPPPPPFGFGVPAAPVLPF 756 Score = 64.7 bits (156), Expect = 5e-10 Identities = 52/129 (40%), Positives = 65/129 (50%), Gaps = 24/129 (18%) Query: 645 GGAETSHTEPVS---PIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFT 701 GG S P+S IP P P+P + +P+P ++P P P PP+ G+ + P Sbjct: 626 GGTAISPPPPLSGDATIPPPPPLP-EGVGIPSPSSLPGGTAIP--PPPPLPGSARIPPPP 682 Query: 702 PPL----GIPPP----GFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP--PPITPPV 751 PPL GIPPP G+PPPPPP P PG P PP F PG P PP P + Sbjct: 683 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG-GPGIPP---PPPF--PGGPGIPPPPPGM 736 Query: 752 SIPPPHTPP 760 +PPP PP Sbjct: 737 GMPPP--PP 743 Score = 52.0 bits (123), Expect = 3e-06 Identities = 55/189 (29%), Positives = 66/189 (34%), Gaps = 33/189 (17%) Query: 787 VPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPP 846 VPP+ P+ P PP GT + P P P+ G P P PP PPP Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGT--IIPPP------PAPGDSTTPP---PPPPPPPPPPP 611 Query: 847 -----HLQRFP-------LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG-----PFPP 889 + P + PP P+ PPP P G +P P + G P PP Sbjct: 612 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671 Query: 890 HGPFVR----PGGMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 944 R P +PG G P P P P + PP P P P P Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 731 Query: 945 PPPSQQPPP 953 PPP PP Sbjct: 732 PPPGMGMPP 740 Score = 41.6 bits (96), Expect = 0.004 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 23/140 (16%) Query: 274 VEESKKE--DTTAVTTTAPA-----AAVPPAPT------ATVPAAAAPAAAS-----PPP 315 +E++KKE +A T P A VPPAP +P AP ++ PPP Sbjct: 546 LEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 605 Query: 316 PQAPFGFPGDG-MQQPAYTQHQNMDQFQPRMMGIQQ----DPMHHQVPLPPNGQMPGFGL 370 P P PG + P P + G P+ V +P +PG Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 665 Query: 371 LPTPPFPPMAQPVIPPTPPV 390 +P PP P + + PP PP+ Sbjct: 666 IPPPPPLPGSARIPPPPPPL 685 Score = 41.6 bits (96), Expect = 0.004 Identities = 41/179 (22%), Positives = 52/179 (29%), Gaps = 49/179 (27%) Query: 211 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDE 270 PP P P ++ ++ +P P A PPP Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL---------------- 648 Query: 271 PEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQP 330 PE V T P +P + P P +A PPP P PG+ Sbjct: 649 PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP--LPGEA---- 702 Query: 331 AYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPP 389 +P PP G G+ P PPFP P IPP PP Sbjct: 703 -------------------------GMPPPPPPLPGGPGIPPPPPFP--GGPGIPPPPP 734 Score = 37.4 bits (85), Expect = 0.081 Identities = 34/104 (32%), Positives = 38/104 (36%), Gaps = 33/104 (31%) Query: 628 PDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLP----VPVPPIPVPAPITVPPPQVP 683 P GIP P + G + P P PLP +P PP P P +PPP Sbjct: 686 PGSAGIPPPPPPLPGEAG---------MPPPPPPLPGGPGIPPPP-PFPGGPGIPPP--- 732 Query: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRP 727 PP P PPP FG GVP P P L P Sbjct: 733 -------------PPGMGMP---PPPPFGFGVPAAPVLPFGLTP 760 Score = 36.2 bits (82), Expect = 0.18 Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 25/127 (19%) Query: 852 PLMPPR-PMPPHMMHRGPP-PGPGGFAMPPPHG-------MKGPFPPHGPFVRPGGM--- 899 P +P R P+PP PP PG G +PPP P PP P PGG+ Sbjct: 565 PSVPSRAPVPP-----APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS 619 Query: 900 --PGL-GGPGPGPGGPEDRDGR-QQPPQQPQQQPQPQAPQQPQQQQQQQPPP----SQQP 951 P L GG P P D PP P+ P P PPP ++ P Sbjct: 620 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 679 Query: 952 PPTQQQP 958 PP P Sbjct: 680 PPPPPLP 686 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 102 bits (255), Expect = 2e-21 Identities = 85/232 (36%), Positives = 98/232 (42%), Gaps = 45/232 (19%) Query: 673 APITVPP--PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFN 730 A ITVPP P P P PP+ G PP P P PPPPPPPP PG Sbjct: 568 AAITVPPSVPSRAPVPPAPPLPG--DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625 Query: 731 PMHLPPGFLPPG----PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSA 786 + PP LP G PPPP++ +IPPP PP+ G S G+A Sbjct: 626 CISSPPS-LPGGTAISPPPPLSGDATIPPP--PPLP--------EGVGIPSPSSLPGGTA 674 Query: 787 VPPAAP----TNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG 842 +PP P +P PP P G+ G+ P P P G G P PL PG Sbjct: 675 IPPPPPLPGSARIPPPPPPLP----GSAGIPPPP-----PPLPGEAGMPPPPPPLPGGPG 725 Query: 843 MPPPHLQRFPLMPPRPMPPHMMHRGPPPGPG-GFAMPPPHGMKGPFPPHGPF 893 +PPP PP P P + PPP PG G PPP G P P PF Sbjct: 726 IPPP--------PPFPGGPGI----PPPPPGMGMPPPPPFGFGVPAAPVLPF 765 Score = 64.7 bits (156), Expect = 5e-10 Identities = 52/129 (40%), Positives = 65/129 (50%), Gaps = 24/129 (18%) Query: 645 GGAETSHTEPVS---PIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFT 701 GG S P+S IP P P+P + +P+P ++P P P PP+ G+ + P Sbjct: 635 GGTAISPPPPLSGDATIPPPPPLP-EGVGIPSPSSLPGGTAIP--PPPPLPGSARIPPPP 691 Query: 702 PPL----GIPPP----GFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP--PPITPPV 751 PPL GIPPP G+PPPPPP P PG P PP F PG P PP P + Sbjct: 692 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG-GPGIPP---PPPF--PGGPGIPPPPPGM 745 Query: 752 SIPPPHTPP 760 +PPP PP Sbjct: 746 GMPPP--PP 752 Score = 52.0 bits (123), Expect = 3e-06 Identities = 55/189 (29%), Positives = 66/189 (34%), Gaps = 33/189 (17%) Query: 787 VPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPP 846 VPP+ P+ P PP GT + P P P+ G P P PP PPP Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGT--IIPPP------PAPGDSTTPP---PPPPPPPPPPP 620 Query: 847 -----HLQRFP-------LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG-----PFPP 889 + P + PP P+ PPP P G +P P + G P PP Sbjct: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680 Query: 890 HGPFVR----PGGMPGLGG-PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 944 R P +PG G P P P P + PP P P P P Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 740 Query: 945 PPPSQQPPP 953 PPP PP Sbjct: 741 PPPGMGMPP 749 Score = 41.6 bits (96), Expect = 0.004 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 23/140 (16%) Query: 274 VEESKKE--DTTAVTTTAPA-----AAVPPAPT------ATVPAAAAPAAAS-----PPP 315 +E++KKE +A T P A VPPAP +P AP ++ PPP Sbjct: 555 LEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 614 Query: 316 PQAPFGFPGDG-MQQPAYTQHQNMDQFQPRMMGIQQ----DPMHHQVPLPPNGQMPGFGL 370 P P PG + P P + G P+ V +P +PG Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 674 Query: 371 LPTPPFPPMAQPVIPPTPPV 390 +P PP P + + PP PP+ Sbjct: 675 IPPPPPLPGSARIPPPPPPL 694 Score = 41.6 bits (96), Expect = 0.004 Identities = 41/179 (22%), Positives = 52/179 (29%), Gaps = 49/179 (27%) Query: 211 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDE 270 PP P P ++ ++ +P P A PPP Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL---------------- 657 Query: 271 PEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQP 330 PE V T P +P + P P +A PPP P PG+ Sbjct: 658 PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP--LPGEA---- 711 Query: 331 AYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPP 389 +P PP G G+ P PPFP P IPP PP Sbjct: 712 -------------------------GMPPPPPPLPGGPGIPPPPPFP--GGPGIPPPPP 743 Score = 37.4 bits (85), Expect = 0.081 Identities = 34/104 (32%), Positives = 38/104 (36%), Gaps = 33/104 (31%) Query: 628 PDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLP----VPVPPIPVPAPITVPPPQVP 683 P GIP P + G + P P PLP +P PP P P +PPP Sbjct: 695 PGSAGIPPPPPPLPGEAG---------MPPPPPPLPGGPGIPPPP-PFPGGPGIPPP--- 741 Query: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRP 727 PP P PPP FG GVP P P L P Sbjct: 742 -------------PPGMGMP---PPPPFGFGVPAAPVLPFGLTP 769 Score = 36.2 bits (82), Expect = 0.18 Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 25/127 (19%) Query: 852 PLMPPR-PMPPHMMHRGPP-PGPGGFAMPPPHG-------MKGPFPPHGPFVRPGGM--- 899 P +P R P+PP PP PG G +PPP P PP P PGG+ Sbjct: 574 PSVPSRAPVPP-----APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS 628 Query: 900 --PGL-GGPGPGPGGPEDRDGR-QQPPQQPQQQPQPQAPQQPQQQQQQQPPP----SQQP 951 P L GG P P D PP P+ P P PPP ++ P Sbjct: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688 Query: 952 PPTQQQP 958 PP P Sbjct: 689 PPPPPLP 695 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 102 bits (255), Expect = 2e-21 Identities = 123/413 (29%), Positives = 154/413 (37%), Gaps = 128/413 (30%) Query: 691 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPP 750 V G + P P G PPP PP PP P PG PPG PPGPPP P Sbjct: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP---PG------PPG--PPGPPP---PG 256 Query: 751 VSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQ 810 +PPP P PN RG+ P P P P QP LG Sbjct: 257 QVLPPPLAGP---PN-----RGDR--------------PPPPVLFPGQPFGQPP--LGPL 292 Query: 811 GVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPP 870 P P + PG P PPG PPP Q+ P PP P PP PP Sbjct: 293 PPGPPPPV-------------PGYGP---PPGPPPP--QQGPPPPPGPFPPR------PP 328 Query: 871 GPGGFAM---PPPHGMKGP---FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ 924 GP G + PPPH + GP PP P V P P P G D R PP Sbjct: 329 GPLGPPLTLAPPPH-LPGPPPGAPPPAPHVNPAFF-----PPPTNSGMPTSDSRGPPPTD 382 Query: 925 PQQQPQPQAPQQPQQQQQQQPPPSQQ-----PPPTQQQPQQFRNDNRQQFNS--GRDQER 977 P +P P + PP ++ P ++ + ++ N NR +S R Sbjct: 383 PYGRP-------PPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSD 435 Query: 978 FGRRSFGNRVEN---------------------------------DRERYGN-----RND 999 +G+ +E + + YG+ R+ Sbjct: 436 ASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSR 495 Query: 1000 DRDNSNRDRREWGRRSPDRDRHRD-LEERNRRSSGHRDRERDSRDRESRREKE 1051 +RD+S + +S RDRH D ER+R HRDR+RD RDRE RE+E Sbjct: 496 ERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRD-RDRERDRERE 547 Score = 94.7 bits (234), Expect = 4e-19 Identities = 113/390 (28%), Positives = 146/390 (37%), Gaps = 98/390 (25%) Query: 708 PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLV 767 P GPG PPPP P P P PPG PPGPP P P +PPP P PN Sbjct: 218 PGPAGPGGPPPPFPAGQTPP--RPPLGPPG--PPGPPGPPPPGQVLPPPLAGP---PN-- 268 Query: 768 SGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGL 827 RG+ P P P P QP LG P P + Sbjct: 269 ---RGDR--------------PPPPVLFPGQPFGQPP--LGPLPPGPPPPV--------- 300 Query: 828 LGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM---PPPHGMK 884 PG P PPG PPP Q+ P PP P PP PPGP G + PPPH + Sbjct: 301 ----PGYGP---PPGPPPP--QQGPPPPPGPFPPR------PPGPLGPPLTLAPPPH-LP 344 Query: 885 GP---FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQ 941 GP PP P V P P P G D R PP P +P P + Sbjct: 345 GPPPGAPPPAPHVNPAFFPP-----PTNSGMPTSDSRGPPPTDPYGRPPPY-------DR 392 Query: 942 QQQPPPSQQ-----PPPTQQQPQQFRNDNRQQFNSG--RDQERFGRRSFGNRVEN----- 989 PP ++ P ++ + ++ N NR +S R +G+ +E Sbjct: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAI 452 Query: 990 -----DRERYGNRNDDRDNSNRD------RREWGRRSP-DRDRHRDLEERNRRSSGHRDR 1037 + +R +S +D + +G S +R R RD +S H+ R Sbjct: 453 SLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSR 512 Query: 1038 ERDSRD---RESRREKEEARGKEKPEVTDR 1064 RD D RE RE+E R +++ +R Sbjct: 513 SRDRHDDYYRERSRERERHRDRDRDRDRER 542 Score = 87.4 bits (215), Expect = 7e-17 Identities = 78/227 (34%), Positives = 86/227 (37%), Gaps = 44/227 (19%) Query: 659 PKPLPVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPP 717 P P PP P PA T P PP PP PGPP PP P +PPP GP Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPP-----GPPP--PGQVLPPPLAGPPNRG 270 Query: 718 PPPPPPFLRPGFNPMHLPP-GFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAES 776 PPPP L PG P PP G LPPGPPPP+ P PPP PP Sbjct: 271 DRPPPPVLFPG-QPFGQPPLGPLPPGPPPPV--PGYGPPPGPPP---------------- 311 Query: 777 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 836 G PP P P+ P++L + PGP G P+ P Sbjct: 312 ----PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHL-PGPPPGAPPPA-----------P 355 Query: 837 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGM 883 P PPP P R PP + PPP G PP M Sbjct: 356 HVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402 Score = 79.0 bits (193), Expect = 2e-14 Identities = 53/117 (45%), Positives = 62/117 (52%), Gaps = 16/117 (13%) Query: 652 TEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPP----HQPGPPVVGALQPPAFTPPLGIP 707 T P P+ P P P PP P P +PPP P +P PPV+ QP PPLG Sbjct: 235 TPPRPPLGPPGP-PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFG-QPPLGPL 292 Query: 708 PPGFGPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSI-PPPHTP 759 PPG P V PPP PPPP + G P PPG PP PP P+ PP+++ PPPH P Sbjct: 293 PPGPPPPVPGYGPPPGPPPP--QQGPPP---PPGPFPPRPPGPLGPPLTLAPPPHLP 344 Score = 65.1 bits (157), Expect = 4e-10 Identities = 47/113 (41%), Positives = 54/113 (47%), Gaps = 19/113 (16%) Query: 654 PVSPIPKPLPVPVP---PIPVPAPITVPPPQVPPHQPGPPVVGALQPPA-FTPPLGIPPP 709 P+ P+P P PVP P P P P PP PP P PP +PP PPL + PP Sbjct: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQQGPP--PPPGPFPP-----RPPGPLGPPLTLAPP 340 Query: 710 GFGPGVPP-PPPPPPFLRPGFNPMHLPPGFLPP----GPPPPITPPVSIPPPH 757 PG PP PPP P + P F P G +P GPPP T P PPP+ Sbjct: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPP--TDPYGRPPPY 390 Score = 50.1 bits (118), Expect = 1e-05 Identities = 32/78 (41%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 418 QPCIQ--EVKRHMSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRS-RSRSRDRRRHSP 474 Q C+ E K + S +R+ RSR S R +SR R RH R RSR+R RH Sbjct: 474 QDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRD 533 Query: 475 RSRSQER-RDREKERERR 491 R R ++R RDRE+E R Sbjct: 534 RDRDRDRERDREREYRHR 551 Score = 48.9 bits (115), Expect = 3e-05 Identities = 57/253 (22%), Positives = 80/253 (31%), Gaps = 55/253 (21%) Query: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPF------------------GFPGDGMQQPA 331 P PP P P P PPPP PF PG P Sbjct: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 Query: 332 YTQHQNMDQF-QPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPV 390 H N F P G+ P P G+ P + + P + + P+ Sbjct: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPY---DRGDYGPPGREMDTARTPL 409 Query: 391 QQPFQASFQAQNEPLTQKP---------------------------HQQEMEVEQPCIQE 423 + +N ++ Q ++ + C Sbjct: 410 SEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVL 469 Query: 424 VKRHMSDNRKSRSRSASRSPKRRRSRSGSRSR-RSRHRRSRSRSRDRRRHSPRSRSQER- 481 + S+S +R RSR SR R + RR +SRSRDR R RS+ER Sbjct: 470 ISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERE 529 Query: 482 ----RDREKERER 490 RDR+++RER Sbjct: 530 RHRDRDRDRDRER 542 Score = 48.5 bits (114), Expect = 3e-05 Identities = 34/94 (36%), Positives = 37/94 (39%), Gaps = 9/94 (9%) Query: 867 GPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG--MPGLGGPGPGPGGPEDRDGRQQPPQQ 924 GPP G A P +G FP PGG PG GPG G P Q PP+ Sbjct: 187 GPPGGSSRAAFPQGGRGRGRFPG----AVPGGDRFPGPAGPG---GPPPPFPAGQTPPRP 239 Query: 925 PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 P P P P P Q PPP PP +P Sbjct: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273 Score = 39.3 bits (90), Expect = 0.021 Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 9/78 (11%) Query: 967 QQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEE 1026 + + SG +ER R E R D D+ R+R R DRDR RD E Sbjct: 483 KSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDRE- 541 Query: 1027 RNRRSSGHRDRERDSRDR 1044 RDRER+ R R Sbjct: 542 --------RDREREYRHR 551 Score = 38.9 bits (89), Expect = 0.028 Identities = 35/111 (31%), Positives = 40/111 (36%), Gaps = 21/111 (18%) Query: 290 PAAAVPPAPTATVPAAAAPAAASPP-----PPQAPFGFPGDGMQQPAYTQHQNMDQFQPR 344 PA PP P P P PP PP A G P G + P QP Sbjct: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA--GPPNRGDRPPPPVLFPGQPFGQPP 288 Query: 345 MMGIQQDPMHHQVPLPPNGQ--MPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 + PLPP +PG+G P PP PP P PP P +P Sbjct: 289 LG-----------PLPPGPPPPVPGYGPPPGPP-PPQQGPPPPPGPFPPRP 327 Score = 30.8 bits (68), Expect = 7.6 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 358 PLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 P P G P F TPP PP+ P PP PP P Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPG-PPGPPGPPP 254 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 102 bits (255), Expect = 2e-21 Identities = 105/367 (28%), Positives = 137/367 (37%), Gaps = 72/367 (19%) Query: 657 PIPKPLPVPVPPIPVPA---PITVPPPQVPPH--QPGPPVVGALQPPAFTPPLGIPPPGF 711 P + L P+ PA P P+ P H QP P + AL+PP TPP P Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287 Query: 712 G-----------PGVPPPPPPPPFLRPGFNPMHLPP----------------GFLPPGP- 743 G P PP P PP L+ +P PP FLP P Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347 Query: 744 -----PPPITPP-VSIPP---PHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTN 794 PPP PP +++PP P +PP S P L A + ++ +++ ++ P + P Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPP-- 404 Query: 795 LPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP-- 852 P+PPV P S + V+P QAP + L A P +P PP PP P Sbjct: 405 -PSPPVQAPFSPPASPPVSPSATPPSQAPPS--LAAPPLQVP-PSPPASPPMSPSATPPP 460 Query: 853 -LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP---FPPHGPFVRPGGMPGLGGPGPG 908 PP PP + + PP P A PP + P FP PF +P P Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520 Query: 909 PGGPEDRDG-RQQPPQQPQQQPQPQAPQQPQQQQQQ----------------QPPPSQQP 951 P P Q P P P QAP++P PPPS+ P Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 Query: 952 PPTQQQP 958 T P Sbjct: 581 SSTLSGP 587 Score = 90.5 bits (223), Expect = 8e-18 Identities = 96/360 (26%), Positives = 125/360 (34%), Gaps = 61/360 (16%) Query: 634 PKKPENEVAQNGGAETSH-TEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVV 692 P P ++ + G+ T T P P P+ PP P + +PP Q PP P P + Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378 Query: 693 GALQPPAFTPPLGI----------PPPGFGPGVPPPPPPPPFLRPGFNP-------MHLP 735 L P+ P + PPP P PP P + P P + P Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438 Query: 736 PGFLPPGPP--PPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPT 793 P +PP PP PP++P + PP PP++ P L + PP AP Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL----------------AKPPPQAPP 482 Query: 794 NLPTPPV----TQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP--LQRPPGMPPPH 847 L TPP+ + P S G +P + + +T A P L LQ PP P Sbjct: 483 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542 Query: 848 LQRFPLMPPRPMPPHMMHRGP------PPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPG 901 + P PP P P + GP PGP PPP GP + Sbjct: 543 TLQAPRRPPTPGPDTSV-SGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSA 596 Query: 902 LGGPGPGPG---GPEDRDGRQQPPQQPQQQPQPQA----PQQPQQQQQQQPPPSQQPPPT 954 P G GPE PP P A P P + P PP T Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 Score = 83.6 bits (205), Expect = 1e-15 Identities = 85/280 (30%), Positives = 101/280 (36%), Gaps = 44/280 (15%) Query: 654 PVSPIPKP--LPVPVPPIPVPAPITVPPPQVPPHQPGPPVV--GALQPPAFTPPLGIPPP 709 P SP P P PP P + PP QVPP P P + A PP PPL PP Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471 Query: 710 GFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP---PGPPPPITP--PVSIPPPHTPPISIP 764 PPP PP P + PP P P P P P++ PPP PP+ Sbjct: 472 QLAK--PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 Query: 765 NLVSGARGNAESGDSVKMYGSAVPPAAPT-----NLPTP-PVTQPVSLLGTQGVAPG-PV 817 L+ PPA+PT PTP P T T +APG P Sbjct: 530 PLLQVPPS---------------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 Query: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 877 ++PS+ L G P L P L+ + P PPP A Sbjct: 575 PPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYDSGPEGGAA-----ASPPPDAELAAC 627 Query: 878 PPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG 917 P +GP PP + G PG P P GP DG Sbjct: 628 HPAAWSRGPAPP----LAFRGAPGAPLPWPPATGPGSADG 663 Score = 80.5 bits (197), Expect = 8e-15 Identities = 101/347 (29%), Positives = 120/347 (34%), Gaps = 54/347 (15%) Query: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVV- 692 P P +A+ A + TE P P P P PP P + +P P Sbjct: 160 PGTPSPAMARRSRA--AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217 Query: 693 -----GALQPPAF------TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP 741 G LQ PA PL P GP P P +P P L Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARS-GPSARGTPRAPA------HPSQPKPKGLQA 270 Query: 742 GPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVT 801 PP +TPP P P+S L + + S + PP+ T LP+PP T Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS--------PSAPPSLQT-LPSPPAT 321 Query: 802 QPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPP 861 P + G LQA + L P L PL PP PP L PL P P PP Sbjct: 322 PPSQATTSLGSPT-----LQATHSFL--PSPPLSPLATPPPQAPPALALPPLQAP-PSPP 373 Query: 862 HMMHRGP-----PPGPGGFAMPPPHGMKGPF-PPHGPFVRPGGMPGLGGPGPGPGGPEDR 915 P P P A+ H ++ PF PP P V+ P P P P Sbjct: 374 ASPPLSPLATPSPQAPNALAV---HLLQAPFSPPPSPPVQAPFSP----PASPPVSPSAT 426 Query: 916 DGRQQPPQ--QPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 Q PP P Q P P P PPP Q PPP P Q Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP-QAPPPLAAPPLQ 472 Score = 62.8 bits (151), Expect = 2e-09 Identities = 76/287 (26%), Positives = 107/287 (37%), Gaps = 51/287 (17%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQ 194 A G +++P+A T + +PP P S PP+ T S PA P PS + + Q Sbjct: 286 ALGPLSSSPLA---TPSPSAPPSP----SAPPSLQTLPSPPATP--PSQATTSLGSPTLQ 336 Query: 195 TTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQK 254 T L PP PAL + +QA + + P P A P P+ Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPAL---ALPPLQAPPSPPASPPLSP----LATPSPQAP 389 Query: 255 TAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPP 314 A LL + P ++ +P A+ P +P+AT P+ A P+ A+PP Sbjct: 390 NALAVHLLQA-PFSPPPSPPVQAP---------FSPPASPPVSPSATPPSQAPPSLAAPP 439 Query: 315 ----------PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPP--- 361 PP +P P P + + P+ P +P PP Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499 Query: 362 NGQMP--GFGLLPTPPF---PPMAQPV-------IPPTPPVQQPFQA 396 GQ P LP P PP A PV +PP+PP QA Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546 Score = 57.0 bits (136), Expect = 1e-07 Identities = 74/274 (27%), Positives = 93/274 (33%), Gaps = 54/274 (19%) Query: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-PV 691 +P P + A P PL + PP P + PP Q P P P Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501 Query: 692 VGALQPPAFTP--PLGIPPPGFGP-------GVPPPPPPPPFLRPGFNPMHLPPG----- 737 P A P PL PPP P VPP PP P L+ P P Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561 Query: 738 -----FLPPGPPPP--ITPPVSIPPPH---------TPPISIPNLVSGARGNAESGDSVK 781 L PGPPPP +P ++ P + P + SG G A + Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621 Query: 782 MYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPP 841 +A PAA + P P P++ G G AP P P+TG G+ GL + Sbjct: 622 AELAACHPAAWSRGPAP----PLAFRGAPG-APLP----WPPATG-PGSADGLCTIYETE 671 Query: 842 GMPPPHLQRFPLMPPRPMP-PHMMHRGPPPGPGG 874 G P P P + GP PG G Sbjct: 672 G------------PESATPAPGALDPGPSPGTSG 693 Score = 47.0 bits (110), Expect = 1e-04 Identities = 62/259 (23%), Positives = 80/259 (30%), Gaps = 41/259 (15%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 213 S P P + + P Q TP A P L + LQT PP Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320 Query: 214 -PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPE 272 P S A + +QA + L + P P A PPP+ A L Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSP----LATPPPQAPPALALPPL---------- 366 Query: 273 AVEESKKEDTTAVTTTAPAAAVPPAPTA-TVPAAAAPAAASPPPP-QAPFGFPGDGMQQP 330 ++ + + A P AP A V AP + P PP QAPF P P Sbjct: 367 ---QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423 Query: 331 AYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPV 390 + T PP+ P + P+PP P P P P Sbjct: 424 SATPPSQA---------------------PPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462 Query: 391 QQPFQASFQAQNEPLTQKP 409 P A +P Q P Sbjct: 463 PPPLAAPPLQLAKPPPQAP 481 Score = 46.2 bits (108), Expect = 2e-04 Identities = 64/261 (24%), Positives = 82/261 (31%), Gaps = 31/261 (11%) Query: 154 SPP--PPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211 SPP PPV S+ PP+QA P+ Q+P S + T Q + Q Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 Query: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQ----PSEQ----KAAFPPPEQKTAFDKKLLD 263 KP A +QA+ + + P Q PS A PPP+ LL Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533 Query: 264 RFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFP 323 P A + T AP P P +V A +P PP P P Sbjct: 534 ---VPPSPPA----------SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 Query: 324 GDGMQQPAYTQHQNMDQFQP-RMMGIQQDPMHHQVPLPPNG------QMPGFGLLPTPPF 376 + P H + P + G P PP + P PP Sbjct: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640 Query: 377 PPMAQPVIP-PTPPVQQPFQA 396 P P P PP P A Sbjct: 641 AFRGAPGAPLPWPPATGPGSA 661 Score = 44.7 bits (104), Expect = 5e-04 Identities = 86/362 (23%), Positives = 103/362 (28%), Gaps = 102/362 (28%) Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPPP--PPFLRP-----------------GFNPMHL 734 A P A P L P P PG P PPPP P LR G + Sbjct: 14 ARTPAARAPGLLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 735 PPGFLPPGPPPPITPPVS-----IPPPHTP---PISIPNLVSG----------------- 769 P GP PP S PP P+S P SG Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130 Query: 770 ---ARGNAESGD--SVKMYGSAVPPAAPT-NLPTPPVTQPVSLLGTQGVAPGPVIGL--- 820 ARG A S G+ + PT P+P + + GT+ P P Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 Query: 821 ---QAPSTGLLGA------RPGLIPLQRPP---GMPPPHLQRF-----PLMPPRPMPPHM 863 + P + A P +RP G+ P + PL P P Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 Query: 864 MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLG------------GPGPGPGG 911 RG P P + P P G++ PP R P LG P P Sbjct: 251 --RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308 Query: 912 PEDRDGRQQPPQQPQQQPQ---------------PQAPQQPQQQQQQQPPPSQQPPPTQQ 956 P PP P Q P P P Q PP+ PP Q Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368 Query: 957 QP 958 P Sbjct: 369 PP 370 Score = 43.5 bits (101), Expect = 0.001 Identities = 61/297 (20%), Positives = 100/297 (33%), Gaps = 61/297 (20%) Query: 153 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 212 G P P PPT+ SV + + +++ A + + + G LQ Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR--RPSAGGGLQ---------- 226 Query: 213 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPE 272 +P S +L ++ +++ ++ P+ +A P + K + L P Sbjct: 227 RPASRSLSSSATP----LSSPARSGPSARGTPRAPAHPSQPKPKGLQAL--------RPP 274 Query: 273 AVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAAS-PPPPQAPFGFPGDGMQQPA 331 V +K+ A+ + + P+P+A +A P+ + P PP P + P Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334 Query: 332 YTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP--TPPFPPMAQPVIP---- 385 Q F P P + PP P L P PP PP + P+ P Sbjct: 335 L---QATHSFLP-------SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384 Query: 386 --------------------PTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQ 422 P+PPVQ PF P P Q + P +Q Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441 >gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] Length = 411 Score = 97.8 bits (242), Expect = 5e-20 Identities = 88/264 (33%), Positives = 111/264 (42%), Gaps = 38/264 (14%) Query: 655 VSPIPKPLPVPVP---PIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGF 711 +SP P P+P P+P IP P P ++P P P Q P+ + P + P+ IP P Sbjct: 92 LSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGP-ISGPVQIPGPFR 150 Query: 712 GPGVPPPPPPPPFLRPGFNPMHLP-PGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGA 770 GP P P P P P P PG +P P PI P+S P P PIS+P + G Sbjct: 151 GPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPG--PISVP--IPGP 206 Query: 771 RGNAESGDSVKMYGSAVPPAAPTNLPTP-PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 829 SG P + P P P P+ P+S G PGP+ G + G Sbjct: 207 IPGPISG----------PISGPNPGPIPGPIPGPIS-----GPNPGPIPG------PISG 245 Query: 830 ARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPP 889 PGLIP P + P P++ P P P + G GPG P G P Sbjct: 246 PNPGLIPGPIPGPISGPG----PIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPG 301 Query: 890 HGPFVRPGGMPGLG---GPGPGPG 910 P + PG PG G P PGPG Sbjct: 302 LAPILGPGSGPGSGSVPAPIPGPG 325 Score = 94.4 bits (233), Expect = 6e-19 Identities = 94/312 (30%), Positives = 120/312 (38%), Gaps = 59/312 (18%) Query: 660 KPLPVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPP 718 K +P + P P P P +P P Q+P PG IP P GP P Sbjct: 86 KGIPAALSPGPGPIPAPIPGPAQIPGPLPG----------------SIPGPIPGPAQIPS 129 Query: 719 PPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGD 778 P P P P P+ +P F P P PI+ P IP P + P S PN Sbjct: 130 PIPAPIPGPISGPVQIPGPFRGP-IPGPISGPAPIPGPISGPFSGPN------------- 175 Query: 779 SVKMYGSAVPPAAPTNLPTP---PVTQPVSLLGTQGVAPGPVIG-LQAPSTG-LLGARPG 833 +P P +P P P+ P+S + G PGP+ G + P+ G + G PG Sbjct: 176 -----PGPIPGPNPGPIPGPISGPIPGPIS-VPIPGPIPGPISGPISGPNPGPIPGPIPG 229 Query: 834 LIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGP--PPGPGGFAMPPPHGMKGPFP--P 889 I P +P P P + P P+P + GP P P +P P ++GP P Sbjct: 230 PISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILS 289 Query: 890 HGPFVRPGGMPGLG---GPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPP 946 G PG +PGL GPG GPG P P P + P Q P Sbjct: 290 PGRMRSPGSLPGLAPILGPGSGPGS----------GSVPAPIPGPGSLPAPAPLWPQSPD 339 Query: 947 PSQQPPPTQQQP 958 S P TQ P Sbjct: 340 ASDFLPDTQLFP 351 Score = 46.6 bits (109), Expect = 1e-04 Identities = 58/206 (28%), Positives = 71/206 (34%), Gaps = 21/206 (10%) Query: 764 PNLVSGARGN-AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQA 822 P V G RG A + V ++ P P+ + P +P ++ GP Q Sbjct: 30 PQRVPGQRGRGARAAPLVPAASASAPQRGPSGIL--PAAEP-TICSLHQAWGGPGCRAQK 86 Query: 823 PSTGLLGARPGLIPLQRP---------PGMPP---PHLQRFPLMPPRPMPPHMMHRGPPP 870 L PG IP P PG P P + P P P+P + GP Sbjct: 87 GIPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPIS--GPVQ 144 Query: 871 GPGGFAMPPPHGMKGPFPPHGPFVRP--GGMPG-LGGPGPGPGGPEDRDGRQQPPQQPQQ 927 PG F P P + GP P GP P G PG + GP PGP P P Sbjct: 145 IPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIP 204 Query: 928 QPQPQAPQQPQQQQQQQPPPSQQPPP 953 P P P P P P P Sbjct: 205 GPIPGPISGPISGPNPGPIPGPIPGP 230 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 97.1 bits (240), Expect = 9e-20 Identities = 107/364 (29%), Positives = 137/364 (37%), Gaps = 59/364 (16%) Query: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPG-------PPVVGALQPPAFTPPLGI 706 P S +P PLP PP+ P ++PPP +PP P PP V P PP G+ Sbjct: 522 PYSQMPPPLPTMPPPV---LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578 Query: 707 PPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI---------TPPVSIPPPH 757 PP G PPP PPP L P LPP L PPP+ TPP IPPP Sbjct: 579 PPSLSSAG-PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPG 637 Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNL---PTPPVTQPVSLLGTQGVAP 814 P P L + A S S ++ P PT + PP T L Q P Sbjct: 638 VPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPL---QSAGP 694 Query: 815 GPVIGLQAPST------GLLGARPGLIPLQRPPGMPPPHLQRFPLMPP--RPMPPHMMHR 866 + +AP + + GL P P ++ P+ P PP + Sbjct: 695 SEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYL 754 Query: 867 GPPPGPGGFAMPP-----PHGMKGPFP---------PHGPFVRPGGMPGLGGP---GPGP 909 P GP F P +GP P P GP R G P G G P Sbjct: 755 ESPRGP-RFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIP 813 Query: 910 GGPEDR----DGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ-QPPPTQQQPQQFRND 964 GP + P+ Q PQ + P+ QQ QQ P SQ +P ++P + Sbjct: 814 RGPASQFYITPSTSLSPR--QSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSS 871 Query: 965 NRQQ 968 N+Q+ Sbjct: 872 NQQK 875 Score = 72.4 bits (176), Expect = 2e-12 Identities = 81/297 (27%), Positives = 109/297 (36%), Gaps = 48/297 (16%) Query: 732 MHLPPGFLP--------PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMY 783 M +PP F+P P PPP+ PP S+PPP PP ++P V M Sbjct: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPP-SLPPPVMPP-ALPATV----------PPPGMP 561 Query: 784 GSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGM 843 +PP+ PT++P P + +S G V P P + P L P L PP M Sbjct: 562 PPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVL--PPPSLSSTAPPPVM 619 Query: 844 PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLG 903 P P L PP +PP + +G PP +PP + P P RP +P Sbjct: 620 PLPPLS--SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP--RPALLPTPV 675 Query: 904 GPGPGP----------GGPEDRDGRQQP------PQQPQQQPQ-----PQAPQQPQQQQQ 942 G P GP ++ + P P Q AP QP + Sbjct: 676 SFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVK 735 Query: 943 QQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRND 999 P S P + + +F+ R E G R G R + R GNR D Sbjct: 736 DMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFE-GNRPD 791 Score = 63.5 bits (153), Expect = 1e-09 Identities = 92/369 (24%), Positives = 125/369 (33%), Gaps = 76/369 (20%) Query: 654 PVSPIPKPLPVPVPPI-PVPAPITVPPPQVPP---------------------HQPGPPV 691 P P+P P PV +P P P + P P HQ Sbjct: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74 Query: 692 V---GALQPPAFTPPLGIPPPGFGPGVPPPPPPPP-----------------FLR----- 726 V L PP PP +P G+G PPPPP PP L Sbjct: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134 Query: 727 -PGFNPMHL-PPGFLPPGPPPPITPPVS--IPPPHTPPISIPNLVSGARGNAESGDSVKM 782 PG PM L P PP PP PP +PPP PP P + + Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYP-----PTSSQPYLPPAQP 189 Query: 783 YGSAVPPAAPTNLPTPPVTQPVS-----LLGTQGVAPGPVIGLQAPSTGLLGARPGLIPL 837 S PP+ PTP + S L +Q P PS G ++ P Sbjct: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP- 248 Query: 838 QRPPGMPPPH---LQRFPL-MPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF 893 PP PP + +Q+ PL + P P P M P + + H Sbjct: 249 --PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS--TMTPQEQQQYWYRQHLLS 304 Query: 894 VRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQP-QPQAPQQPQQQQQQQPPPSQQPP 952 ++ L G GP +D +P ++ P Q P+ P ++ PPP+++ P Sbjct: 305 LQQRTKVHLPGHKKGPVVAKD---TPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVP 361 Query: 953 P--TQQQPQ 959 P ++PQ Sbjct: 362 PPLPPEEPQ 370 Score = 62.8 bits (151), Expect = 2e-09 Identities = 82/325 (25%), Positives = 99/325 (30%), Gaps = 94/325 (28%) Query: 685 HQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGF--------------- 729 H P PPV PP PP+ +P GPG P GF Sbjct: 13 HYPPPPV-----PPP--PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQ 65 Query: 730 -----------NPMHLPPGFLPPGPPPPITPPVSI-----PPPHTPPISIPNLVSGARGN 773 P HLPP PP PPPP+ P PPP PP P L S + Sbjct: 66 QMHQKQMQCVLQPHHLPP---PPLPPPPVMPGGGYGDWQPPPPPMPPPPGPAL-SYQKQQ 121 Query: 774 AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPG 833 + P P L +PP + PV PG + PS + Sbjct: 122 QYKHQMLHHQRDGPPGLVPMELESPPESPPVP--------PGSYM---PPSQSYM----- 165 Query: 834 LIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF 893 PP PPP PP P++ PP P PP P P + Sbjct: 166 ------PPPQPPPSYY-----PPTSSQPYL----PPAQPSPSQSPPSQSYLAPTPSYSSS 210 Query: 894 VRPG------GMPGLGGPGPGPGGPEDRDGRQQ-----PPQQP-------QQQPQPQAPQ 935 L P P + Q PP P QQ+P + Sbjct: 211 SSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAK 270 Query: 936 QPQQQQQQ---QPPPSQQPPPTQQQ 957 +QQQ +P PS P QQQ Sbjct: 271 NKSTEQQQAAPEPDPSTMTPQEQQQ 295 Score = 58.5 bits (140), Expect = 3e-08 Identities = 75/277 (27%), Positives = 106/277 (38%), Gaps = 56/277 (20%) Query: 830 ARPGLIPLQRPPGM--PPPHLQRFPLMPPRPMPPHMMHRGP---PPGPGGFAMPPPHGMK 884 +RPG+ P PPG PPP + + P RP P P PP P PPP Sbjct: 1501 SRPGMYP---PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP---- 1553 Query: 885 GPFPPHGPFVRP------------GGMPGLGGPGPGPG-GPEDRDGRQQPPQQPQQQPQP 931 P PP P ++P GL G E + P P P P Sbjct: 1554 -PLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPP 1612 Query: 932 -QAPQQPQQQQQQQPPPSQQPPPTQQ-----QPQQFRNDNRQQFNSGR------------ 973 + P PP +PPP QQ + + +Q G Sbjct: 1613 VHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPER 1672 Query: 974 ---DQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRR 1030 + E G+R +R E DRE Y +R + N D R++ R DR+ HRD +R+R Sbjct: 1673 STFETEHAGQRDRYDR-ERDREPYFDR---QSNVIADHRDFKR---DRETHRD-RDRDRG 1724 Query: 1031 SSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGG 1067 + DR+R R+R R ++ ++ +K + R GG Sbjct: 1725 VIDY-DRDRFDRERRPRDDRAQSYRDKKDHSSSRRGG 1760 Score = 55.1 bits (131), Expect = 4e-07 Identities = 88/337 (26%), Positives = 118/337 (35%), Gaps = 80/337 (23%) Query: 726 RPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGS 785 RPG P PPG P PPP PP SI P PP S Sbjct: 1502 RPGMYP---PPGSYRP-PPPMGKPPGSIVRPSAPPAR----------------------S 1535 Query: 786 AVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP-------GLIPLQ 838 +VP P +P PP P L P PVI P T + GL Sbjct: 1536 SVPVTRPP-VPIPPPPPPPPL-----PPPPPVI---KPQTSAVEQERWDEDSFYGLWDTN 1586 Query: 839 RPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG 898 G+ +P P+ P PPP + PP GP P G Sbjct: 1587 DEQGLNSEFKSETAAIPSAPVLP----------------PPP--VHSSIPPPGPV--PMG 1626 Query: 899 MPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 MP + P P + GR + +Q P + + + P P + T+ Sbjct: 1627 MPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGE-----RITLRPDPLPERSTFETEHAG 1681 Query: 959 QQFRNDNRQQFNSGRDQERFGRRSFG-----NRVENDRERYGNRNDDRDNSNRDRREWGR 1013 Q+ R D RD+E + R + DRE + +R+ DR + DR + R Sbjct: 1682 QRDRYDRE------RDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDR 1735 Query: 1014 -RSPDRDRHRDLEERNRRSSGHRDR-ERDSRDRESRR 1048 R P DR + ++ SS R +R S DR+S R Sbjct: 1736 ERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDR 1772 Score = 53.9 bits (128), Expect = 8e-07 Identities = 69/279 (24%), Positives = 92/279 (32%), Gaps = 49/279 (17%) Query: 716 PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAE 775 PPPP PPP PP LP P P + P P S + + A+ Sbjct: 15 PPPPVPPP-----------PPVALPEASPGPGYSSSTTP---AAPSSSGFMSFREQHLAQ 60 Query: 776 SGDSVKMYGSAVP-PAAPTNLPTPPVTQPVSLLG-----------TQGVAPGPVIGLQAP 823 +M+ + P +LP PP+ P + G PGP + Q Sbjct: 61 LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120 Query: 824 STGLLGARPGLIPLQR--PPGMPPPHLQRFPLMPPRP----MPPHMMHRGPPPGPGGFAM 877 + ++ QR PPG+ P L+ P PP P MPP + PP P + Sbjct: 121 QQ----YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYY- 175 Query: 878 PPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQ-----QPPQQPQQQPQPQ 932 PP + PP P P P P Q P Q P Sbjct: 176 -PPTSSQPYLPPAQPSPSQ-SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233 Query: 933 APQQPQQQQQQQPPPSQQPPP-----TQQQPQQFRNDNR 966 P Q + Q PP PP QQ+P + N+ Sbjct: 234 RPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNK 272 Score = 49.3 bits (116), Expect = 2e-05 Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 1/131 (0%) Query: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 349 P PP P A A+ P +S P AP ++ Q Q + Q + M Sbjct: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75 Query: 350 QDPMH-HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408 P H PLPP MPG G P PP P P Q+ Q Q + Sbjct: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135 Query: 409 PHQQEMEVEQP 419 P ME+E P Sbjct: 136 PGLVPMELESP 146 Score = 47.0 bits (110), Expect = 1e-04 Identities = 76/299 (25%), Positives = 104/299 (34%), Gaps = 54/299 (18%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPP-----TQATPNSVPAVPQL--PSSDA-----FAAVA 190 PV E VT S P S EPP + P P PQ P DA AA A Sbjct: 329 PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388 Query: 191 QLFQTTQGQ-------------QLQQILQTFQQ----PPKPQSPALDNAV------MAQV 227 Q Q + QLQQILQ +QQ PP Q+ ++D + Q Sbjct: 389 HWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQF 448 Query: 228 QAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV-- 285 Q + + + EQ ++P +Q ++K+ + +A + +E + Sbjct: 449 QHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK---TWQGHMKATQSYLQEKVNSFQN 505 Query: 286 -------TTTAPAAAVP----PAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQPAY 332 + P VP P P T+P P + PP PP P P GM P Sbjct: 506 MKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVM 565 Query: 333 TQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPG-FGLLPTPPFPPMAQPVIPPTPPV 390 P M V PP+ G +LP P A P + P PP+ Sbjct: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624 Score = 47.0 bits (110), Expect = 1e-04 Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 58/172 (33%) Query: 629 DWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPG 688 D+ P+ ++ Q + + + P P P PP+ P P ++ P PP + Sbjct: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP-PGSIVRPSAPPARSS 1536 Query: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPP--PPPPPFLRP------------------- 727 PV PP+ IPPP PPP PPPPP ++P Sbjct: 1537 VPVT--------RPPVPIPPPP-----PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583 Query: 728 ------GFN-------------PMHLPP----GFLPPGPPPPITPPVSIPPP 756 G N P+ PP PPGP P PP+S PPP Sbjct: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635 Score = 47.0 bits (110), Expect = 1e-04 Identities = 53/189 (28%), Positives = 67/189 (35%), Gaps = 51/189 (26%) Query: 680 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLP-PGF 738 PQ+ H P P LQ + P + PP + P P PP +RP P P Sbjct: 1483 PQMADHLP--PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540 Query: 739 LPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG-------------- 784 PP P PP PP + PP PP+ P + E D YG Sbjct: 1541 RPPVPIPPPPPPPPL-PP-PPPVIKPQT---SAVEQERWDEDSFYGLWDTNDEQGLNSEF 1595 Query: 785 ---SAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPP 841 +A P+AP LP PPV + PGPV P+ PP Sbjct: 1596 KSETAAIPSAPV-LPPPPVHSSIP-------PPGPV------------------PMGMPP 1629 Query: 842 GMPPPHLQR 850 PP +Q+ Sbjct: 1630 MSKPPPVQQ 1638 Score = 43.9 bits (102), Expect = 9e-04 Identities = 65/286 (22%), Positives = 92/286 (32%), Gaps = 44/286 (15%) Query: 155 PPPPVKVSSEPPTQATPNSVPA-------VPQLPSSDAFAA-----VAQLFQTTQ--GQQ 200 PPPPV PP A P + P P PSS F + +AQL Q Q +Q Sbjct: 15 PPPPVP---PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71 Query: 201 LQQILQTFQ--QPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFD 258 +Q +LQ PP P P + Q P P PPP ++ Sbjct: 72 MQCVLQPHHLPPPPLPPPPVMPGGGYGDWQ------PPPPPMP-------PPPGPALSYQ 118 Query: 259 KKLLDRFD----YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASP- 313 K+ + D P + + E P + +PP+ + P P+ P Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178 Query: 314 -PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 372 P P P P+ + + Q H Q LP + P Sbjct: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS----- 233 Query: 373 TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQ 418 P ++ P PP P + Q EPL + E +Q Sbjct: 234 RPSQGHSKSQLLAPPPPSAPPGNKT-TVQQEPLESGAKNKSTEQQQ 278 Score = 43.5 bits (101), Expect = 0.001 Identities = 61/301 (20%), Positives = 104/301 (34%), Gaps = 89/301 (29%) Query: 155 PPPPVKVSSEPPTQATPNSVPAVP---QLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211 PPP S PPT + P PA P Q P S ++ A P Sbjct: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT--------------------P 205 Query: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSE----QKAAFPPPEQKTAFDKKLLDRFDY 267 S + + ++ Q+ + +P++PS+ + PPP +K + + Sbjct: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQ--- 262 Query: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327 E +E K +T AP P P+ P Sbjct: 263 ----EPLESGAKNKSTEQQQAAPE----PDPSTMTP-----------------------Q 291 Query: 328 QQPAYTQHQNMDQFQPR----MMGIQQ---------DPMHHQVPLPPNGQMPGFGLLPTP 374 +Q Y Q++ Q R + G ++ +P+ +V +P Q+P P Sbjct: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351 Query: 375 PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKS 434 P PP + V PP PP EP ++ P +++ ++Q +Q H +++ Sbjct: 352 PLPPPNEEVPPPLPP------------EEPQSEDP-EEDARLKQ--LQAAAAHWQQHQQH 396 Query: 435 R 435 R Sbjct: 397 R 397 Score = 43.1 bits (100), Expect = 0.001 Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 14/164 (8%) Query: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQ---PRMM 346 P +PP P +P PPPP P P Q+ +HQ + + P ++ Sbjct: 82 PPPPLPPPPV--MPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLV 139 Query: 347 GIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPP-------MAQPVIPPT--PPVQQPFQAS 397 ++ + P+PP MP PP PP +QP +PP P Q P S Sbjct: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQS 199 Query: 398 FQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441 + A + + + S +R S+ S S+ Sbjct: 200 YLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243 Score = 42.0 bits (97), Expect = 0.003 Identities = 54/226 (23%), Positives = 81/226 (35%), Gaps = 40/226 (17%) Query: 295 PPAPTA--TVPAAAAPAAASPPPPQAPFGFPGDGMQ-QPAYTQHQNMDQ----------- 340 P AP A +VP P PPPP P P ++ Q + + + D+ Sbjct: 1528 PSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587 Query: 341 -------FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQ- 392 F+ I P+ LPP P +P P PM P + PPVQQ Sbjct: 1588 EQGLNSEFKSETAAIPSAPV-----LPPP---PVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639 Query: 393 -PFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSG 451 + + Q P+ + + + + E +++ R R R R R Sbjct: 1640 VDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRY-----DRERDREP 1694 Query: 452 SRSRRSR---HRRSRSRSRDRRRHSPRSRSQERRDREK-ERERRQK 493 R+S R R R+ R R R DR++ +RERR + Sbjct: 1695 YFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740 Score = 37.4 bits (85), Expect = 0.081 Identities = 74/350 (21%), Positives = 113/350 (32%), Gaps = 81/350 (23%) Query: 146 ENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQIL 205 +N ++ G PPP PP P S+ P P + + V + Sbjct: 1497 QNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR-PSAPPARSSVPVTR-------------- 1541 Query: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265 PP P P L P P K EQ+ + + Sbjct: 1542 PPVPIPPPPPPPPL------------------PPPPPVIKPQTSAVEQERWDEDSFYGLW 1583 Query: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325 D +DE E K E TA +AP PP ++ PPP P G P Sbjct: 1584 DTNDEQGLNSEFKSE--TAAIPSAPVLPPPPVHSSI-----------PPPGPVPMGMP-- 1628 Query: 326 GMQQPAYTQHQNMDQFQPRMMG---IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 382 M +P Q Q +D R + ++Q P ++ L P+ P+ Sbjct: 1629 PMSKPPPVQ-QTVDYGHGRDISTNKVEQIPYGERITLRPD---------------PL--- 1669 Query: 383 VIPPTPPVQQPFQASFQAQNEPL-TQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441 P + F+ Q + ++ + + + I + + D R R R Sbjct: 1670 ------PERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDR 1723 Query: 442 SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERR---DREKER 488 R RR R R++S RD++ HS R R DR+ +R Sbjct: 1724 GVIDYDRDRFDRERRPRDDRAQS-YRDKKDHSSSRRGGFDRPSYDRKSDR 1772 Score = 35.8 bits (81), Expect = 0.23 Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 35/212 (16%) Query: 868 PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRD-----GRQQPP 922 P PG GG M P H + PP P+ P G P +R+ R++ Sbjct: 1171 PEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYW 1227 Query: 923 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP--------QQFRND-NRQ-QFNSG 972 ++ ++ Q + ++ + PPS+ ++ P Q D NR+ + + Sbjct: 1228 RECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMD 1287 Query: 973 RDQERFGR------RSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRS-------PDRD 1019 RD +R R RS N + D YG D++++ R+R P D Sbjct: 1288 RDVDRISRPMDMYDRSLDNEWDRD---YGRPLDEQESQFRERDIPSLPPLPPLPPLPPLD 1344 Query: 1020 RHRDLEERNRRSSGHRDRERDSRDRESRREKE 1051 R+RD R R+ H +RD RDR R +E Sbjct: 1345 RYRDDRWREERNREH-GYDRDFRDRGELRIRE 1375 Score = 33.9 bits (76), Expect = 0.89 Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 46/201 (22%) Query: 854 MPPRPMPPHMMHRGPPPGPG----GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 909 +PPR RGPP GPG G +GPF P PG GG P Sbjct: 1134 IPPRRAGSR--ERGPPRGPGSRERGLGRSDFGRDRGPFRPE---------PGDGGEKMYP 1182 Query: 910 GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 969 R +PP+ P + ++ ++ P + P +++ + Sbjct: 1183 ------YHRDEPPRAPWNHGE-------ERGHEEFPLDGRNAPMERERLDDW-------- 1221 Query: 970 NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSP---DRDRHRDLEE 1026 D+ER+ R + ++ E Y NR D + RR P D +R +D++E Sbjct: 1222 ----DRERYWRECERDYQDDTLELY-NREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276 Query: 1027 RNRRSSGHRDRERDSRDRESR 1047 R RD +RD DR SR Sbjct: 1277 DYNREM-ERDMDRDV-DRISR 1295 Score = 33.5 bits (75), Expect = 1.2 Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 45/130 (34%) Query: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325 D+ EP+ + +++ T++ PP P + PPPP G P Sbjct: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPP-----------PGSYRPPPPM---GKPPG 1523 Query: 326 GMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPV 383 + +P+ P VP+ PP +P PP PP P Sbjct: 1524 SIVRPS------------------APPARSSVPVTRPP---------VPIPPPPP--PPP 1554 Query: 384 IPPTPPVQQP 393 +PP PPV +P Sbjct: 1555 LPPPPPVIKP 1564 Score = 32.7 bits (73), Expect = 2.0 Identities = 28/90 (31%), Positives = 30/90 (33%), Gaps = 17/90 (18%) Query: 873 GGFAMPPP----HGMKGPFPPHGPFVRPGGM------PGLGGPGPGPGGPEDRDGRQQPP 922 G +MPPP M P P P V P + P L P PG P PP Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPP----VMPP 567 Query: 923 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPP 952 P P P P PPP PP Sbjct: 568 SLPTSVP---PPGMPPSLSSAGPPPVLPPP 594 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 96.7 bits (239), Expect = 1e-19 Identities = 96/344 (27%), Positives = 119/344 (34%), Gaps = 73/344 (21%) Query: 656 SPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPP------LG---- 705 S P LP + + P P PP PP + L P TPP LG Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374 Query: 706 ------IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP--PPITPPVSIPPPH 757 +P P P PPP PP L LPP PP PP PP++ P++ P P Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQAPPSPPASPPLS-PLATPSPQ 426 Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPV 817 P +L+ P +P P+PPV P S + V+P Sbjct: 427 APNALAVHLLQA-------------------PFSPP--PSPPVQAPFSPPASPPVSPSAT 465 Query: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP---LMPPRPMPPHMMHRGPPPGPGG 874 QAP + L A P +P PP PP P PP PP + + PP P Sbjct: 466 PPSQAPPS--LAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522 Query: 875 FAMPPPHGMKGP---FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG-RQQPPQQPQQQPQ 930 A PP + P FP PF +P P P P Q P P P Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582 Query: 931 PQAPQQPQQQQQQ----------------QPPPSQQPPPTQQQP 958 QAP++P PPPS+ P T P Sbjct: 583 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626 Score = 90.5 bits (223), Expect = 8e-18 Identities = 96/360 (26%), Positives = 125/360 (34%), Gaps = 61/360 (16%) Query: 634 PKKPENEVAQNGGAETSH-TEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVV 692 P P ++ + G+ T T P P P+ PP P + +PP Q PP P P + Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417 Query: 693 GALQPPAFTPPLGI----------PPPGFGPGVPPPPPPPPFLRPGFNP-------MHLP 735 L P+ P + PPP P PP P + P P + P Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477 Query: 736 PGFLPPGPP--PPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPT 793 P +PP PP PP++P + PP PP++ P L + PP AP Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL----------------AKPPPQAPP 521 Query: 794 NLPTPPV----TQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP--LQRPPGMPPPH 847 L TPP+ + P S G +P + + +T A P L LQ PP P Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581 Query: 848 LQRFPLMPPRPMPPHMMHRGP------PPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPG 901 + P PP P P + GP PGP PPP GP + Sbjct: 582 TLQAPRRPPTPGPDTSV-SGPRLTLALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSA 635 Query: 902 LGGPGPGPG---GPEDRDGRQQPPQQPQQQPQPQA----PQQPQQQQQQQPPPSQQPPPT 954 P G GPE PP P A P P + P PP T Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695 Score = 83.6 bits (205), Expect = 1e-15 Identities = 85/280 (30%), Positives = 101/280 (36%), Gaps = 44/280 (15%) Query: 654 PVSPIPKP--LPVPVPPIPVPAPITVPPPQVPPHQPGPPVV--GALQPPAFTPPLGIPPP 709 P SP P P PP P + PP QVPP P P + A PP PPL PP Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510 Query: 710 GFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP---PGPPPPITP--PVSIPPPHTPPISIP 764 PPP PP P + PP P P P P P++ PPP PP+ Sbjct: 511 QLAK--PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568 Query: 765 NLVSGARGNAESGDSVKMYGSAVPPAAPT-----NLPTP-PVTQPVSLLGTQGVAPG-PV 817 L+ PPA+PT PTP P T T +APG P Sbjct: 569 PLLQVPPS---------------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613 Query: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 877 ++PS+ L G P L P L+ + P PPP A Sbjct: 614 PPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYDSGPEGGAA-----ASPPPDAELAAC 666 Query: 878 PPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG 917 P +GP PP + G PG P P GP DG Sbjct: 667 HPAAWSRGPAPP----LAFRGAPGAPLPWPPATGPGSADG 702 Score = 61.2 bits (147), Expect = 5e-09 Identities = 77/292 (26%), Positives = 106/292 (36%), Gaps = 45/292 (15%) Query: 131 LLDMAAGTSNAAPVAENVTNNEGSPPPPVKVS-SEPPTQATPNSVPAVPQLPSSDAFAAV 189 L A T A P + ++T +P P S S PP+ T S PA P PS + Sbjct: 313 LQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP--PSQATTSLG 370 Query: 190 AQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFP 249 + Q T L PP PAL + +QA + + P P A P Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPAL---ALPPLQAPPSPPASPPLSP----LATP 423 Query: 250 PPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPA 309 P+ A LL + P ++ +P A+ P +P+AT P+ A P+ Sbjct: 424 SPQAPNALAVHLLQA-PFSPPPSPPVQAP---------FSPPASPPVSPSATPPSQAPPS 473 Query: 310 AASPP----------PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL 359 A+PP PP +P P P + + P+ P +P Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 533 Query: 360 PP---NGQMP--GFGLLPTPPF---PPMAQPV-------IPPTPPVQQPFQA 396 PP GQ P LP P PP A PV +PP+PP QA Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585 Score = 57.0 bits (136), Expect = 1e-07 Identities = 74/274 (27%), Positives = 93/274 (33%), Gaps = 54/274 (19%) Query: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-PV 691 +P P + A P PL + PP P + PP Q P P P Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540 Query: 692 VGALQPPAFTP--PLGIPPPGFGP-------GVPPPPPPPPFLRPGFNPMHLPPG----- 737 P A P PL PPP P VPP PP P L+ P P Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600 Query: 738 -----FLPPGPPPP--ITPPVSIPPPH---------TPPISIPNLVSGARGNAESGDSVK 781 L PGPPPP +P ++ P + P + SG G A + Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660 Query: 782 MYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPP 841 +A PAA + P P P++ G G AP P P+TG G+ GL + Sbjct: 661 AELAACHPAAWSRGPAP----PLAFRGAPG-APLP----WPPATG-PGSADGLCTIYETE 710 Query: 842 GMPPPHLQRFPLMPPRPMP-PHMMHRGPPPGPGG 874 G P P P + GP PG G Sbjct: 711 G------------PESATPAPGALDPGPSPGTSG 732 Score = 46.2 bits (108), Expect = 2e-04 Identities = 64/261 (24%), Positives = 82/261 (31%), Gaps = 31/261 (11%) Query: 154 SPP--PPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211 SPP PPV S+ PP+QA P+ Q+P S + T Q + Q Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQ----PSEQ----KAAFPPPEQKTAFDKKLLD 263 KP A +QA+ + + P Q PS A PPP+ LL Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572 Query: 264 RFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFP 323 P A + T AP P P +V A +P PP P P Sbjct: 573 ---VPPSPPA----------SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619 Query: 324 GDGMQQPAYTQHQNMDQFQP-RMMGIQQDPMHHQVPLPPNG------QMPGFGLLPTPPF 376 + P H + P + G P PP + P PP Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679 Query: 377 PPMAQPVIP-PTPPVQQPFQA 396 P P P PP P A Sbjct: 680 AFRGAPGAPLPWPPATGPGSA 700 Score = 43.1 bits (100), Expect = 0.001 Identities = 68/303 (22%), Positives = 102/303 (33%), Gaps = 46/303 (15%) Query: 138 TSNAAPV---AENVTNNEGSPPPPVKVSSEPPTQATPNSVPAV--PQL--PSSDAFAAVA 190 +S+A P+ A + + G+P P P+Q P + A+ PQ+ P DA A+ Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAH-----PSQPKPKGLQALRPPQVTPPRKDAAPALG 297 Query: 191 QLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPP 250 L + Q PP + +++ Q+ +P+ P + P Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357 Query: 251 PEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAA 310 P P + + T T + + P +P AT P A PA Sbjct: 358 PAT-----------------PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400 Query: 311 ASPP---PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPG 367 A PP PP P P + P+ P + + P P Q P Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQA--------PNALAVHLLQAPFSPPPSPPVQAP- 451 Query: 368 FGLLPTPPFPPMAQPV--IPPT---PPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQ 422 F +PP P A P PP+ PP+Q P P P Q + P +Q Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511 Query: 423 EVK 425 K Sbjct: 512 LAK 514 Score = 37.0 bits (84), Expect = 0.11 Identities = 86/356 (24%), Positives = 102/356 (28%), Gaps = 98/356 (27%) Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPPP--PPFLR-----------------PGFNPMHL 734 A P A P L P P PG P PPPP P LR G + Sbjct: 14 ARTPAARAPGLLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 735 PPGFLPPGPP---------PPITPPVS-----IPPPHTP---PISIPNLVSG-------- 769 P GP P PP S PP P+S P SG Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130 Query: 770 ------------ARGNAESGD--SVKMYGSAVPPAAPT-NLPTPPVTQPVSLLGTQGVAP 814 ARG A S G+ + PT P+P + + GT+ P Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190 Query: 815 GPVIG------LQAPSTGLLGA------RPGLIPLQRPP---GMPPPHLQRF-----PLM 854 P + P + A P +RP G+ P + PL Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250 Query: 855 PPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP---GG 911 P P RG P P + P P G++ PP R P LG P Sbjct: 251 SPARSGPSA--RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 912 PEDRDGRQQPPQQPQ-----------QQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 956 P Q PP P P P AP P Q PS P Q Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 96.7 bits (239), Expect = 1e-19 Identities = 91/247 (36%), Positives = 106/247 (42%), Gaps = 53/247 (21%) Query: 684 PHQ---PGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLP 740 PHQ PP A P + G+PPPG P PPP PP P LPPG P Sbjct: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPP-------PGALPPGIPP 259 Query: 741 PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVP-PAAPTNLPTPP 799 PPPP+ P + H PP + G G G +G + P P P +P P Sbjct: 260 AMPPPPMPPGAA---GHGPPSA------GTPGAGHPG-----HGHSHPHPFPPGGMPHPG 305 Query: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP---------PPHLQR 850 ++Q Q GP GL P G G+ G P + PPGMP PP Sbjct: 306 MSQ------MQLAHHGPH-GLGHPHAGPPGSG-GQPPPRPPPGMPHPGPPPMGMPPRGPP 357 Query: 851 F--PLMPPRPMPPHMMHRGPPP-----GPGGFAMPPPHG-MKGPFPPHGPFVRPGGMPGL 902 F P+ P PMPPH M RGPPP G G PPP+G +GP PP P RP P Sbjct: 358 FGSPMGHPGPMPPHGM-RGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPP-- 414 Query: 903 GGPGPGP 909 GP GP Sbjct: 415 RGPLRGP 421 Score = 95.9 bits (237), Expect = 2e-19 Identities = 96/265 (36%), Positives = 112/265 (42%), Gaps = 66/265 (24%) Query: 678 PPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPG-FGPGVPPPPPPPPFLRPGFNPMHLPP 736 PPP P PVV +L + PP G+PPPG F P VPPP PP + P P +PP Sbjct: 216 PPPSAPN-----PVVSSLG--SGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPP 268 Query: 737 GFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVP-PAAPTNL 795 G GPP TP P +G + P P P + Sbjct: 269 GAAGHGPPSAGTPGAGHPG---------------------------HGHSHPHPFPPGGM 301 Query: 796 PTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMP 855 P P ++Q Q GP GL P G G+ G P + PPGMP P P Sbjct: 302 PHPGMSQ------MQLAHHGP-HGLGHPHAGPPGS-GGQPPPRPPPGMPHPG------PP 347 Query: 856 PRPMPPHMMHRGPPPG-PGGFAMP-PPHGMKGP---FPPHGPFVRPGGMPGLG---GPGP 907 P MPP RGPP G P G P PPHGM+GP PPHG + P P G GP P Sbjct: 348 PMGMPP----RGPPFGSPMGHPGPMPPHGMRGPPPLMPPHG-YTGPPRPPPYGYQRGPLP 402 Query: 908 GPGGPEDRDGRQQPPQQPQQQPQPQ 932 P P R PP+ P + P PQ Sbjct: 403 -PPRPTPRP--PVPPRGPLRGPLPQ 424 Score = 81.3 bits (199), Expect = 5e-15 Identities = 81/241 (33%), Positives = 93/241 (38%), Gaps = 67/241 (27%) Query: 655 VSPIPKPLPVPVPPIPVPAPITVPP-----PQVPPHQPGPPV----VGALQPPAFTPPLG 705 VS + LP P P P P VPP P +PP P PP+ G P A TP G Sbjct: 225 VSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP--G 282 Query: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPM----HLPPGFLPP--GPP-----PPITPPVSIP 754 PG G P P PP PG + M H P G P GPP PP PP +P Sbjct: 283 AGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMP 342 Query: 755 PPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAP 814 P PP+ +P RG PP P+ P Sbjct: 343 HPGPPPMGMP-----PRG-------------------------PPFGSPMG-------HP 365 Query: 815 GPVIGLQAPSTGLLGARPGLIP--LQRPPGMPPPHLQRFPLMPPRPMP-PHMMHRGPPPG 871 GP+ P G+ G P + P PP PP QR PL PPRP P P + RGP G Sbjct: 366 GPM-----PPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420 Query: 872 P 872 P Sbjct: 421 P 421 Score = 72.0 bits (175), Expect = 3e-12 Identities = 59/180 (32%), Positives = 66/180 (36%), Gaps = 35/180 (19%) Query: 813 APGPVI-----GLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 867 AP PV+ GL P G+ P +P PPG PP + P MPP PMPP G Sbjct: 220 APNPVVSSLGSGLPPPGMPPPGSFPPPVP---PPGALPPGIP--PAMPPPPMPPGAAGHG 274 Query: 868 PPPGPGGFAMPPPHGMKGPFP-PHGPFVRPG---------GMPGLGGPGPGPGGPEDRDG 917 PP A P HG P P P G PG G GLG P GP G G Sbjct: 275 PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPG----SG 330 Query: 918 RQQPPQQPQQQPQPQAPQ-----------QPQQQQQQQPPPSQQPPPTQQQPQQFRNDNR 966 Q PP+ P P P P P PP + PP P + R Sbjct: 331 GQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPR 390 Score = 58.9 bits (141), Expect = 3e-08 Identities = 45/128 (35%), Positives = 57/128 (44%), Gaps = 13/128 (10%) Query: 634 PKKPENEVAQNG--GAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPV 691 P + ++A +G G H P +P P P P +P P P PP +PP GPP Sbjct: 304 PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGP---PPMGMPPR--GPPF 358 Query: 692 VGALQPPAFTPPLGI--PPPGFGP-GVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPIT 748 + P PP G+ PPP P G PP PPP+ G+ LPP P PP P Sbjct: 359 GSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPY---GYQRGPLPPPRPTPRPPVPPR 415 Query: 749 PPVSIPPP 756 P+ P P Sbjct: 416 GPLRGPLP 423 Score = 41.6 bits (96), Expect = 0.004 Identities = 42/115 (36%), Positives = 48/115 (41%), Gaps = 15/115 (13%) Query: 290 PAAAVPPA-PTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMM-- 346 P A+PP P A P P AA PP A G PG G P + H + F P M Sbjct: 249 PPGALPPGIPPAMPPPPMPPGAAGHGPPSA--GTPGAG--HPGH-GHSHPHPFPPGGMPH 303 Query: 347 -GIQQDPMHHQVPL---PPNGQMPGFGLLPTP-PFPPMAQPVIPP--TPPVQQPF 394 G+ Q + H P P+ PG G P P P P M P PP PP PF Sbjct: 304 PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPF 358 Score = 40.4 bits (93), Expect = 0.010 Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 41/116 (35%) Query: 303 PAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ------DPMHHQ 356 P A P + PPP+ P G P G P MG+ PM H Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPG----------------PPPMGMPPRGPPFGSPMGHP 365 Query: 357 VPLPPNGQ------MPGFGLL-------------PTPPFPPMAQPVIPPTPPVQQP 393 P+PP+G MP G P PP P +P +PP P++ P Sbjct: 366 GPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421 Score = 32.3 bits (72), Expect = 2.6 Identities = 12/25 (48%), Positives = 15/25 (60%) Query: 657 PIPKPLPVPVPPIPVPAPITVPPPQ 681 P+P P P P PP+P P+ P PQ Sbjct: 400 PLPPPRPTPRPPVPPRGPLRGPLPQ 424 Score = 32.0 bits (71), Expect = 3.4 Identities = 33/125 (26%), Positives = 41/125 (32%), Gaps = 39/125 (31%) Query: 292 AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQD 351 A PP P+A P ++ + PPP G P G P Sbjct: 212 ADAPPPPSAPNPVVSSLGSGLPPP-----GMPPPGSFPP--------------------- 245 Query: 352 PMHHQVPLPPNGQMPGFGL---LPTPPFPPMAQPVIPP---TPPVQQPFQASFQAQNEPL 405 P+PP G +P G+ +P PP PP A PP TP P P Sbjct: 246 ------PVPPPGALPP-GIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPP 298 Query: 406 TQKPH 410 PH Sbjct: 299 GGMPH 303 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 96.7 bits (239), Expect = 1e-19 Identities = 85/248 (34%), Positives = 107/248 (43%), Gaps = 49/248 (19%) Query: 654 PVSPIPKPLP------VPVPPIPV--PAPITVP-PPQVPPHQPG--PPVVGALQPPAFTP 702 P P+P+ LP +P+PP+P PAP P PPQ+PP PG PP P P Sbjct: 243 PRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPA-----PVVHPP 297 Query: 703 PLGIPPPGFGPGVPPPP----PPPPFLRPGFNPMHLP-PGFLPPGPPPPITPPVSIPPPH 757 G+ PP PGV PP PP P + P + +H P PG PP P + PP P H Sbjct: 298 ASGVHPP--APGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPA--PGVHPPA--PGVH 351 Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPV 817 P + G +G V V PAAP P P P P P Sbjct: 352 PPAPGVHPPAPGVHPPPSAG--VHPQAPGVHPAAPAVHPQAPGVHP----------PAPG 399 Query: 818 IGLQAPST-----GLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 872 + QAP G+ + PG+ P +PPG+ P + + PP PMPP + P GP Sbjct: 400 MHPQAPGVHPQPPGVHPSAPGVHP--QPPGVHPSNP---GVHPPTPMPPMLRPPLPSEGP 454 Query: 873 GGFAMPPP 880 G PPP Sbjct: 455 GNIPPPPP 462 Score = 81.3 bits (199), Expect = 5e-15 Identities = 90/303 (29%), Positives = 106/303 (34%), Gaps = 62/303 (20%) Query: 657 PIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVP 716 P P LP P + P PPP + P PP+ +L PP PP G+P P P P Sbjct: 218 PAPPSLPAGPPGVKRP-----PPPLMNGLPPRPPLPESLPPP---PPGGLPLPPMPPTGP 269 Query: 717 PP--PPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNA 774 P PP PP L P PG PP P + PP S P P + Sbjct: 270 APSGPPGPPQLPPP------APGVHPPAPV--VHPPASGVHPPAPGVH------------ 309 Query: 775 ESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGL 834 PPA + P P V P T GV P P G+ P+ G+ PG+ Sbjct: 310 -------------PPAPGVHPPAPGVHPP-----TSGVHP-PAPGVHPPAPGVHPPAPGV 350 Query: 835 IPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGP---PPGPGGFAMPPPHGMKGPFPPHG 891 P P P + P P P + P P PG PP GM P Sbjct: 351 HPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPG--VHPPAPGMHPQAPGVH 408 Query: 892 PFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP 951 P PG P G P P G + P P P P P + PP P Sbjct: 409 P-QPPGVHPSAPGVHPQPPGVHPSNPGVHP---PTPMPPMLRPPLPSEGPGNIPP----P 460 Query: 952 PPT 954 PPT Sbjct: 461 PPT 463 Score = 78.6 bits (192), Expect = 3e-14 Identities = 82/253 (32%), Positives = 97/253 (38%), Gaps = 28/253 (11%) Query: 719 PPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGD 778 PP PP L G + PP L G PP P S+PPP PP +P G A SG Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP--PPGGLPLPPMPPTGPAPSGP 274 Query: 779 SVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPG---PVIGLQAPSTGLLGARPGLI 835 +PP AP P PV P + G APG P G+ P+ G+ G+ Sbjct: 275 PGP---PQLPPPAPGVHPPAPVVHPPA-SGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330 Query: 836 PLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP----HGMKGPFPPHG 891 P PG+ PP P P P +H PP PG PPP H P Sbjct: 331 P--PAPGVHPPAPGVHPPAPGVHPPAPGVH---PPAPG--VHPPPSAGVHPQAPGVHPAA 383 Query: 892 PFVRPGGMPGLGGPGPGPGGPEDRDGRQQP----PQQPQQQPQPQA--PQQPQQQQQQQP 945 P V P PG+ P PG P+ QP P P PQP P P Sbjct: 384 PAVHPQA-PGVHPPAPGM-HPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPM 441 Query: 946 PPSQQPPPTQQQP 958 PP +PP + P Sbjct: 442 PPMLRPPLPSEGP 454 Score = 45.4 bits (106), Expect = 3e-04 Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 17/116 (14%) Query: 848 LQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG--MPGLGGP 905 +++ P P P P + R PPP G PP P PP PGG +P + Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPP------PGGLPLPPMPPT 267 Query: 906 GPGPGGPEDRDGRQQPPQQPQQQP--QPQAP-QQPQQQQQQQPPPSQQPPPTQQQP 958 GP P GP PPQ P P P AP P P P PP P Sbjct: 268 GPAPSGPPG------PPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHP 317 Score = 42.7 bits (99), Expect = 0.002 Identities = 36/107 (33%), Positives = 44/107 (41%), Gaps = 11/107 (10%) Query: 290 PAAAVPPAPTATV-PAAAAPAAASPPP-PQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347 PA V P P+A V P A A+P PQAP G+ PA H P+ G Sbjct: 360 PAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAP------GVHPPAPGMHPQAPGVHPQPPG 413 Query: 348 IQQD-PMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 + P H P PP G+ P P PPM +P +P P P Sbjct: 414 VHPSAPGVH--PQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIP 458 Score = 40.8 bits (94), Expect = 0.007 Identities = 41/137 (29%), Positives = 45/137 (32%), Gaps = 12/137 (8%) Query: 288 TAPAAAVPPAPTATVPAAAA--PAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRM 345 T PA + PP P P A P A PP + P G+ PA H P Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326 Query: 346 MGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN--- 402 G+ P V P G P P P P A V PP P V P A Q Sbjct: 327 SGVH--PPAPGVHPPAPGVHP-----PAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGV 379 Query: 403 EPLTQKPHQQEMEVEQP 419 P H Q V P Sbjct: 380 HPAAPAVHPQAPGVHPP 396 Score = 39.3 bits (90), Expect = 0.021 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 9/107 (8%) Query: 293 AVPPAPTATVPAA----AAPAAASPP-PPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347 ++PP P +P PA + PP PPQ P P G+ PA H P G Sbjct: 250 SLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPP--PAPGVHPPAPVVHPPASGVHPPAPG 307 Query: 348 IQQDPMHHQVPLPPNGQMPGFGL-LPTPPFPPMAQPVIPPTPPVQQP 393 + P P P P G+ P P P A V PP P V P Sbjct: 308 V-HPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPP 353 Score = 37.4 bits (85), Expect = 0.081 Identities = 29/82 (35%), Positives = 31/82 (37%), Gaps = 18/82 (21%) Query: 313 PPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 372 P PP P G PG P P M G+ P PLP + P G LP Sbjct: 218 PAPPSLPAGPPGVKRPPP------------PLMNGLPPRP-----PLPESLPPPPPGGLP 260 Query: 373 TPPFPPMA-QPVIPPTPPVQQP 393 PP PP P PP PP P Sbjct: 261 LPPMPPTGPAPSGPPGPPQLPP 282 Score = 33.1 bits (74), Expect = 1.5 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 13/115 (11%) Query: 290 PAAAV-PPAPTATVPAAAA-PAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347 PA V PPAP PA P + PP P G+ PA H P G Sbjct: 304 PAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPG 363 Query: 348 IQQDP---MHHQVP-LPP-----NGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 + P +H Q P + P + Q PG P P P A P + P PP P Sbjct: 364 VHPPPSAGVHPQAPGVHPAAPAVHPQAPGVH-PPAPGMHPQA-PGVHPQPPGVHP 416 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 96.7 bits (239), Expect = 1e-19 Identities = 104/364 (28%), Positives = 123/364 (33%), Gaps = 42/364 (11%) Query: 623 SDTLNPDWKGIPKKPENEV-AQNGGAET-----SHTEPVSPIPKPLPVPVPPIPVPAPIT 676 S P KG P P + + GG T + T P + P P P P P AP Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP-- 1103 Query: 677 VPPPQVPPHQPG----PPVVGALQPPAFTPP-----LGIPPPGFGPGVPPPPPPPP---F 724 +PP PP G PP GA PA TPP L PPP P P PP P Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163 Query: 725 LRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG 784 P P PP P + P P TP + P+ G + G Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG--APTTP 1221 Query: 785 SAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP 844 +A PP+ L TP +G P +P G P P PP Sbjct: 1222 AATPPSPKGGLATP---------SPKGAPTTPAATPPSPKGGPATPPPKGAP--TPPAAT 1270 Query: 845 PPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP--FPPHGPFVRPGGMPGL 902 PP L+ PP P+ PP GG A PP G P P P PG P Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330 Query: 903 GGPGPGPGGPEDRDGRQQPPQQPQQQPQPQ-APQQPQQQQQQQPP---PSQQPPPTQQQP 958 G P P P G P P P + P P ++ PP PS + P P Sbjct: 1331 GAPTPPAVTPPSPKG---TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387 Query: 959 QQFR 962 R Sbjct: 1388 SPKR 1391 Score = 94.4 bits (233), Expect = 6e-19 Identities = 103/375 (27%), Positives = 116/375 (30%), Gaps = 48/375 (12%) Query: 628 PDWKGIPKKPENEVAQNGGAETSHTE---PVSPIPKPLPVP---VPPIPVPAPIT----- 676 P KG P P + A A T + P +P PK P P PP P P T Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007 Query: 677 --VPPPQVPPHQPGPPVVGALQPPAFTPPLGIPP-PGFGPGVPPPPPPPPF--------- 724 PP PP G P A TPP PP P P P P P Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067 Query: 725 ----LRPGFNPMHLPPGFLPP----GPPPPITPPVSIPPPHTPPISIPNLVS----GARG 772 P PP PP GP P +PP TPP L + GA Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127 Query: 773 NAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP 832 + G A PP P PT P P S G G+A P G + Sbjct: 1128 TPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKG--GLATPPPKGAPTTPAATPPSPK 1183 Query: 833 GLIPLQRPPGMP-----PPHLQRFPLMPPRPMPPHMMHRGPPPGP-GGFAMPPPHG--MK 884 G + P G P P + L P P PP P GG A P P G Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243 Query: 885 GPFPPHGPFVRPGGMPGLGGPGPGPGGPED-RDGRQQPPQQPQQQPQPQAPQQPQQQQQQ 943 P P P P G P P P + G PP + P P P+ Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303 Query: 944 QPPPSQQPPPTQQQP 958 PP PP P Sbjct: 1304 SPPKGAPTPPAATPP 1318 Score = 91.7 bits (226), Expect = 4e-18 Identities = 103/369 (27%), Positives = 126/369 (34%), Gaps = 59/369 (15%) Query: 637 PENEVAQNGGAETSHT--EPVSPIPKPLPVP------------VPP--IPVPAPITVPPP 680 PEN ++ G ++ T P P PK P P +PP P P+ + +P P Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896 Query: 681 QVPPHQPGPPVVGALQPPAFTP--------PLGIPPPGFGPGVPPPP---PPPPF---LR 726 + P P P AL + +P P GIP G P PP PP P Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956 Query: 727 PGFNPMHLPPGFLPP----GPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKM 782 P PP PP GP P PP TPP + + A + +V Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016 Query: 783 YGSAVPPAA---PTNLPTPPVTQPVSLLGTQGVAP-------GPVIGLQAPSTGLLGARP 832 PAA P TPP P S G+ P P L +P G A P Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG--PATP 1074 Query: 833 GLIPLQRPPGMPPPHLQRFPLMPP---RPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPP 889 L PP PP + P P PMPP PP P G PPH P Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPP----AATPPSPKGGLATPPHKGAPTTPA 1130 Query: 890 HGPFVRPGGM---PGLGGP-GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 945 P GG+ P G P P P + G PP P+ P A P + Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLAT 1188 Query: 946 PPSQQPPPT 954 P + P T Sbjct: 1189 PSPKGAPTT 1197 Score = 88.6 bits (218), Expect = 3e-17 Identities = 108/365 (29%), Positives = 128/365 (35%), Gaps = 71/365 (19%) Query: 628 PDWKGIPKKPE-NEVAQNGGAET-----SHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQ 681 P KG P P + GG T + T P + P P P P AP T P Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT--PAA 1223 Query: 682 VPPHQPG----PPVVGALQPPAFTPPLGIPPPGFGPGVPPPP----PP---PPFLRPGF- 729 PP G P GA PA TPP P GP PPP PP PP L+ G Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPP----SPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279 Query: 730 NPMHL----PPGFLPPGPP--PPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMY 783 P H P PP P P +PP P TPP + P G+ G Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAP---TPPAATPPSPKGSPGT---------- 1326 Query: 784 GSAVPPAAPTNLPTPPVTQPVSLLGTQ---GVAPGPVIGLQAPSTGLLGARPGLIPLQRP 840 PP P PTPP P S GT P G PS+ P P + Sbjct: 1327 ----PP--PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380 Query: 841 -PGMPPPHLQRFPLMP-PR--PMPPHMMHRGPPPGPG------GFAMPPPHGMKGPFPPH 890 P M PP +R P +P P+ P P ++ P P G A P KG P Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS----KGDLTP- 1435 Query: 891 GPFVRPGGM---PGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPP 947 P V P + P P GP P + P P +P AP+Q + P Sbjct: 1436 -PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494 Query: 948 SQQPP 952 + P Sbjct: 1495 ATPAP 1499 Score = 58.5 bits (140), Expect = 3e-08 Identities = 80/289 (27%), Positives = 98/289 (33%), Gaps = 38/289 (13%) Query: 628 PDWKGIPKKPENEVAQNGGAET-SHT-----EPVSP-----IPKPLPVPVPPIPVP-API 675 P KG P P ++ A T SH P SP IP P P P +P +P Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413 Query: 676 TVPPPQVPPHQPGPPVVGALQPPAFTP------PLGIPPPGFGPGVPPPPPPPPFLRPGF 729 P V P G L PPA TP P P G GP P P Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPATPSSKGDPTL----- 1467 Query: 730 NPMHLPPGFLPPGPPPPITPPVSIPP---PHTP-PISIPNLVSGARGNAESGDSVKMYGS 785 P PP P PP P S P P TP P+ P L + + + + S Sbjct: 1468 -PAVTPPS--PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP--SS 1522 Query: 786 AVPPAAPT----NLPTPPVTQPV-SLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRP 840 P APT + TP P +L+ P P P+ A P P Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582 Query: 841 PGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPP 889 P + P + P +PP + P P A+ PP KGP P Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631 Score = 52.4 bits (124), Expect = 2e-06 Identities = 85/352 (24%), Positives = 115/352 (32%), Gaps = 41/352 (11%) Query: 625 TLNPDWKG-IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIP----VPAPITVPP 679 T +P +G + P+N + G T T P+ P PV P P P V Sbjct: 672 TASPFLEGTVSLAPKNHPVKEG---TLTTLPLVPTASE-NCPVAPSPQNTCAPLATLVLA 727 Query: 680 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPG-- 737 P++P P P + A PP GI V P P G + G Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787 Query: 738 -FLPPGPPP---PITPPVSIPP-------PHTPPISIPNLVSGARGNAESGDSVKMYGSA 786 +L P P ++P PP P TP ++ + VS + +S+ GS Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847 Query: 787 VPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPP 846 PA T+ PTPP P V P G+ P P P +P P Sbjct: 848 DSPAT-THSPTPP--SPKGAPTPSAVTPLSPKGVTLP--------PKETPTPSVVNLPFP 896 Query: 847 HLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 906 + P P P + P A P P G+ P G P P P Sbjct: 897 --KEGPATPAPKQAPALSMTSSSPKKAR-ATPAPKGIPASPSPKGAPTPPAATP----PS 949 Query: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 P GGP + P P P+ + PP+ PP + P Sbjct: 950 P-KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000 Score = 48.9 bits (115), Expect = 3e-05 Identities = 86/407 (21%), Positives = 125/407 (30%), Gaps = 74/407 (18%) Query: 634 PKK-PENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVV 692 PKK P + A S E SP P P P P + +PP P P Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT- 1615 Query: 693 GALQPPAFTPPLGIPPPGFGPGVPPP---PPPPPFLRPGFNPMHLPP-------GFLPP- 741 PPA TP P P GP P P P PP P G P Sbjct: 1616 ----PPAVTP----PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667 Query: 742 -------------------GPPPPITPPVSIPP---PHT-------PPI-SIPNLVSGAR 771 P P TP ++ P P T PPI P+ +G++ Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727 Query: 772 G-------------NAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI 818 G +S + K ++ P P P + P++ + V P P Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKP-- 1785 Query: 819 GLQAPSTGLLGARPGLIPLQRPPGMP--PPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFA 876 ++ S + P +PL P +P PP Q P P + P Sbjct: 1786 --ESASVSAAPSPPVSLPL-APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842 Query: 877 MPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG--PEDRDGRQQPPQQPQQQPQPQAP 934 + PP + G P V G P P P P ++ + + + P+ Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE 1902 Query: 935 QQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRR 981 +Q Q Q ++P +R + + + + G R Sbjct: 1903 EQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLR 1949 Score = 43.5 bits (101), Expect = 0.001 Identities = 82/298 (27%), Positives = 101/298 (33%), Gaps = 53/298 (17%) Query: 130 PLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSD-AFAA 188 P L M TS++ A +G P P + P ATP S P PS A Sbjct: 909 PALSM---TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965 Query: 189 VAQLFQTTQGQQLQQILQTFQQPP--KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKA 246 A + +G + PP P SP A + A T TP P A Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP-AVTPPSPKGSPA 1024 Query: 247 AFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV-----TTTAPAAAVP-----P 296 A P P+ + P A S K A T PAA +P P Sbjct: 1025 ATPFPKGAST-------------PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071 Query: 297 APTATVPAAAAPAAASPPPPQ------APFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQ 350 A T ++ A P AA+PP P+ +P G P PA T P G Sbjct: 1072 A-TPSLKGAPTPPAATPPSPKGGPATPSPKGAP----MPPAAT--------PPSPKGGLA 1118 Query: 351 DPMHHQVPLPPNGQMPG-FGLLPTPPFPPMAQPVIP-PTPPVQQPFQASFQAQNEPLT 406 P H P P P G L TP PP P P TPP + A+ + P T Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174 Score = 43.5 bits (101), Expect = 0.001 Identities = 75/334 (22%), Positives = 121/334 (36%), Gaps = 53/334 (15%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQL----PSSDAF------AAVAQLFQTTQGQQLQQ 203 +PP P K + P + TP S P P P+S A A V Q + ++ Sbjct: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679 Query: 204 ILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPT---QPSEQKAAFPP---------- 250 L+ P P+S + A + T+P PS + + P Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLL 1739 Query: 251 PEQK-TAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVP----------PAPT 299 P QK ++ K D P A ESK +T +T A +P P+P Sbjct: 1740 PVQKDSSKTAKGKDASHSPKGPLAPPESKA--STPLTAAAFEKVLPKPESASVSAAPSPP 1797 Query: 300 ATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL 359 ++P A +P PP Q PG ++ P+ +P + + + P Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS----------KPLAPADEDELLPLIPPE 1847 Query: 360 PPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQ---AQNEPLTQKPHQQEMEV 416 P +G +P +L P P A + PTP +QP + + +++ P +E + Sbjct: 1848 PISGGVPFQSVLVNMPTPKSA-GIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDS 1906 Query: 417 EQPCIQEVKRHMS---DNRKSRSRSASRSPKRRR 447 Q Q+ + + D SRS K+ R Sbjct: 1907 TQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKAR 1940 Score = 42.0 bits (97), Expect = 0.003 Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 31/148 (20%) Query: 277 SKKEDTTAVTTTAPAAAVPPAPTATVPAA----AAPAAASPPPPQAPFGFPGDGMQQPAY 332 SK T + T P+ P P+A P + P +P P FP +G PA Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905 Query: 333 TQHQNMDQFQ---------PRMMGIQQDPMHHQVPLPPNGQMP---GFGLLPTP---PFP 377 Q + P GI P P PP P G P+P P P Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965 Query: 378 PMAQPVIP------------PTPPVQQP 393 P A P P PTPP P Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATP 993 Score = 41.6 bits (96), Expect = 0.004 Identities = 66/278 (23%), Positives = 82/278 (29%), Gaps = 62/278 (22%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQG------QQLQQILQT 207 SP PP + P+ TP S V P +V L +G +Q + T Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914 Query: 208 FQQPPKPQSPALDNAVMAQVQ---------AITAQLKTTPTQPSEQKAAFPP-------- 250 P K ++ + A A K P PS + A PP Sbjct: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974 Query: 251 -----PEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVT---TTAPAAAVPPAPTATV 302 P K A P A S K + P A PP+P + Sbjct: 975 GGPATPSPKGA-----------PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023 Query: 303 PAAAAPAAASPPP---PQAPFG------FPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPM 353 A P AS PP P +P G P PA T P G P Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT--------LPSPKGGPATPS 1075 Query: 354 HHQVPLPPNGQMP---GFGLLPTPPFPPMAQPVIPPTP 388 P PP P G P+P PM PP+P Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113 Score = 38.5 bits (88), Expect = 0.036 Identities = 45/197 (22%), Positives = 67/197 (34%), Gaps = 20/197 (10%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQ 194 A +S P VT PP K + T ++P PA P + AV Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPK---QVATSSSPKKAPATPAPMGAPTLPAVIP--- 1510 Query: 195 TTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKA-AFPPPEQ 253 + +++ + + P P + L A + A + T PS +K A P P++ Sbjct: 1511 -SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569 Query: 254 -------KTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAA 306 K A + Y P S KE T+P+ P P A P + Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAP-----SPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624 Query: 307 APAAASPPPPQAPFGFP 323 A+P P P P Sbjct: 1625 EKGPATPAPKGTPTSPP 1641 Score = 38.1 bits (87), Expect = 0.047 Identities = 67/272 (24%), Positives = 81/272 (29%), Gaps = 47/272 (17%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P A + +G P P + P ATP S P PS Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-------------- 1010 Query: 203 QILQTFQQPP--KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKK 260 PP P SP A + + TP P AA P P+ Sbjct: 1011 --------PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT---- 1058 Query: 261 LLDRFDYDDEPEAVEESKKEDTTAVT---TTAPAAAVPPAPTATVPAAAAPAAASPPPPQ 317 P A S K + P AA PP+P PA +P A P PP Sbjct: 1059 ---------TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG-PATPSPKGA-PMPPA 1107 Query: 318 APFGFPGDGMQQPAYTQHQNMD-QFQPRMMGIQQDPMHHQVPLPPNGQMPG-FGLLPTPP 375 A P G+ P + P G P P P P G L TP Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP- 1166 Query: 376 FPPMAQPVIP-PTPPVQQPFQASFQAQNEPLT 406 PP P P TPP + A+ + P T Sbjct: 1167 -PPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197 Score = 37.7 bits (86), Expect = 0.062 Identities = 62/275 (22%), Positives = 88/275 (32%), Gaps = 28/275 (10%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P A + +GSP P + P TP S P LP++ + +++ Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371 Query: 203 QILQTFQQ------PPKPQ------SPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPP 250 + PP P+ SP D A + + TP + + AA P Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV--TREGAATPS 1429 Query: 251 PEQKT--AFDKKLLDRFDYDDEPEA--VEESKKEDTTAVTTTAPAAAVPPAP----TATV 302 T A L + P+ S K D T T P+ PPAP T++ Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489 Query: 303 PAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVP---- 358 P A A P P P + PA T D P + + P Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Query: 359 LPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 +PP +P P P P A P P + P Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEA-PATPSSKEASSP 1582 Score = 35.4 bits (80), Expect = 0.31 Identities = 56/227 (24%), Positives = 82/227 (36%), Gaps = 43/227 (18%) Query: 671 VPAPITVPPPQVPPHQPGPPVVGALQPPA----FTPPLGIPPPGFGPGVPPPPPPPPFLR 726 +P T P P P A+ P + T LG P GP +PPP P P Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQP----GPTLPPPCSPAPQQC 56 Query: 727 PGFNPMHLPPGFLPPGPPPPITPPVSIPPPHT-------------PPISIPNLVSGARGN 773 P P P P + P+ +P P + P +PNL+ Sbjct: 57 PLSAANQASPF---PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113 Query: 774 AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL-----GTQGVAPGPVIGLQAPSTGLL 828 A A P APT TP + P++L+ Q + P L +P + + Sbjct: 114 A-------ALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAV 166 Query: 829 GARPGLIPLQRP--PGMPPPHLQRFP--LMP-PR--PMPPHMMHRGP 868 +I L P P P +L + P ++P P+ P PP ++ P Sbjct: 167 AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213 Score = 35.4 bits (80), Expect = 0.31 Identities = 45/188 (23%), Positives = 71/188 (37%), Gaps = 33/188 (17%) Query: 145 AENVTNNEGSPPPPVKVSSEP-----PTQATPNSVPAVPQ-LPSSDAFAAVAQLFQTTQG 198 +E V N +G+P PP VS+ P P + + V ++PQ P++ A Q+ TT Sbjct: 193 SEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTT-- 250 Query: 199 QQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFP--PPEQKTA 256 I P P S +L V + A++ ++ P S QK A P PP+ + Sbjct: 251 -----ISSVLISPQNPGSLSLKGPV-SPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS 304 Query: 257 FDKKLLDRFDYD---------------DEPEAVEESKKEDTTAVTTTAPAAAVPPAPT-- 299 L +P S +T + + + +PP P+ Sbjct: 305 LGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRN 364 Query: 300 ATVPAAAA 307 VPA A Sbjct: 365 EVVPATVA 372 Score = 35.0 bits (79), Expect = 0.40 Identities = 63/288 (21%), Positives = 83/288 (28%), Gaps = 42/288 (14%) Query: 149 TNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTF 208 T +PP P + PP + P + A P P + TT Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209 Query: 209 QQPPKPQSPALDNAVMAQVQA--ITAQLKTTPTQPSEQKA------AFPPPEQKTAFDKK 260 P +P A + T K PT P+ A PPP+ Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT---- 1265 Query: 261 LLDRFDYDDEPEAVEESKK-----------EDTTAVTTTAPA---AAVPPAPTATVPAAA 306 P A S K + VT +P A PP T PAA Sbjct: 1266 ---------PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316 Query: 307 APAAASPPPPQAPFGFP-GDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQM 365 P+ P P G P + P+ + P G P + P PP Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376 Query: 366 PGFGLLPTPPFPPMAQPVIP-----PTPPVQQPFQASFQAQNEPLTQK 408 G P P P IP PT P P +A P+T++ Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK-KAPATPVTRE 1423 Score = 31.2 bits (69), Expect = 5.8 Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPP--PGF 711 P+S + P P P P+ VP PQ PLG P P F Sbjct: 57 PLSAANQASPFPSPSTIASTPLEVPFPQ--------------SSSGTALPLGTAPEAPTF 102 Query: 712 GPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISI--PNLVSG 769 P + PP P L +PM P P P+ V++ P S PNL++ Sbjct: 103 LPNLIGPPISPAALALA-SPMIAPTLKGTPSSSAPLA-LVALAPHSVQKSSAFPPNLLTS 160 Query: 770 --ARGNAESGDSVKMYGSAVPPAAPTNLPTPP 799 + AESG + + P TNL P Sbjct: 161 PPSVAVAESGSVITLSAPIAPSEPKTNLNKVP 192 Score = 30.4 bits (67), Expect = 9.9 Identities = 50/198 (25%), Positives = 69/198 (34%), Gaps = 27/198 (13%) Query: 650 SHTEPVSPIPKPLPVPVPPIPVPAPI----TVPPPQVPPHQPG--PPVVGALQPPAFTPP 703 S SP P P + P+ VP P T P P P P ++G PP Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIG---PPISPAA 115 Query: 704 LGIPPPGFGP---GVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPP 760 L + P P G P P + + + F PP +T P S+ + Sbjct: 116 LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF----PPNLLTSPPSVAVAESGS 171 Query: 761 I---SIPNLVSGARGNAESGDSVKM---YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAP 814 + S P S + N S + G+ PP + +P VT S+ GVA Sbjct: 172 VITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASI--QSGVAS 229 Query: 815 GPVIGLQAPSTGLLGARP 832 P P+T L A P Sbjct: 230 LP---QTTPTTTLAIASP 244 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 96.3 bits (238), Expect = 1e-19 Identities = 105/378 (27%), Positives = 132/378 (34%), Gaps = 78/378 (20%) Query: 617 EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKP-------------LP 663 EG DS ++N + PK + + T P P P+ L Sbjct: 130 EGESSDSRSVNDEGSSDPKDIDQD--------NRSTSPSIPSPQDNESDSDSSAQQQMLQ 181 Query: 664 VPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPP 723 P + P +T P PP P P G PP G P P P P P Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP- 240 Query: 724 FLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMY 783 + P P PP P PP P PH PP+ P S + +A S ++ Sbjct: 241 ---VPHTHIQQAPALHPQRPPSPHPPP--HPSPH-PPLQ-PLTGSAGQPSAPSHAQPPLH 293 Query: 784 GSAVP---------------PAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLL 828 G P P P LP P +Q + LGT A P LQ P Sbjct: 294 GQGPPGPHSLQAGPLLQHPGPPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLP----- 347 Query: 829 GARPGLIPLQRPP---GMPP-----PHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 880 A + Q+PP +PP PH++ P P +P H+ PP G P P Sbjct: 348 -ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSP 402 Query: 881 HGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ--PQQQPQPQAPQQPQ 938 M PP P ++P + L P P PP Q PQ QP P +P QP Sbjct: 403 FSMNANLPP-PPALKP--LSSLSTHHPPSAHP--------PPLQLMPQSQPLPSSPAQPP 451 Query: 939 --QQQQQQPPPSQQPPPT 954 Q Q PPP PPT Sbjct: 452 GLTQSQNLPPPPASHPPT 469 Score = 92.4 bits (228), Expect = 2e-18 Identities = 129/507 (25%), Positives = 179/507 (35%), Gaps = 112/507 (22%) Query: 646 GAETSHTEPVSPIPKPLPVPVPPI-------PVPAPITVPPPQVPPHQPGPPVVGALQPP 698 G+ T+ P P PVP I P P PPP PH P P+ G+ P Sbjct: 223 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP 282 Query: 699 AFT----PPL-GIPPPG-----FGPGVPPPPPPPPF-LRPGFNPMHLPPGFLP------- 740 + PPL G PPG GP + P PP PF L P + P G P Sbjct: 283 SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342 Query: 741 --------------------PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV 780 P PP P+ P PPP TP +P + SG S Sbjct: 343 SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS- 401 Query: 781 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQ---GVAPGPVIGLQAPSTGLLGARPGLIPL 837 P + NLP PP +P+S L T P P L P PL Sbjct: 402 -------PFSMNANLPPPPALKPLSSLSTHHPPSAHPPP-----------LQLMPQSQPL 443 Query: 838 QRPPGMPPPHLQRFPLMPPRPM-PPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF-VR 895 P PP Q L PP PP +H+ P P FA + PF P GP + Sbjct: 444 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--FA-------QHPFVPGGPPPIT 494 Query: 896 PGGMPGLGGPGPGPG-------------GPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 942 P P P GPG G G P P Q + +A ++ + Sbjct: 495 PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPES 552 Query: 943 QQPPP-SQQPPPT-------QQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERY 994 PPP S P PT Q +F + +NS + + G+++ RE Sbjct: 553 PPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-- 610 Query: 995 GNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR 1054 + + + R+ + R +R++ ++ +ER R R+ ER ++ S E Sbjct: 611 ----EAIEKAKREAEQKAREEREREKEKE-KEREREREREREAERAAKASSSAHEGR--- 662 Query: 1055 GKEKPEVTDRAGGNKTVEPPISQVGNV 1081 P+++ + EPP + + V Sbjct: 663 -LSDPQLSGPGHMRPSFEPPPTTIAAV 688 Score = 53.5 bits (127), Expect = 1e-06 Identities = 99/422 (23%), Positives = 144/422 (34%), Gaps = 77/422 (18%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 213 SP PP S PP Q S PS+ + A Q G Q Q P Sbjct: 259 SPHPPPHPSPHPPLQPLTGSAGQ----PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314 Query: 214 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 273 PQ L Q A L T+P + P Q ++ P A Sbjct: 315 PQPFGLP----PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 370 Query: 274 VEESKKEDTTAVTTT-APAA----------------AVPPAPTATVPAAAA----PAAAS 312 + K TT + AP A A P P A P ++ P +A Sbjct: 371 MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 430 Query: 313 PPP----PQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGF 368 PPP PQ+ P Q P TQ QN+ P +H P PP Q P Sbjct: 431 PPPLQLMPQSQ-PLPSSPAQPPGLTQSQNLP---PPPASHPPTGLHQVAPQPPFAQHPFV 486 Query: 369 GLLPTPPFPPM--------------AQPVIP---------------PTPPVQQPFQASFQ 399 P P PP AQP P P VQ +A Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 546 Query: 400 AQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSR------SASRSPKRRRSRSGSR 453 A+ EP + P + E P + + H S + + S +R+ +GS+ Sbjct: 547 AE-EPESPPPPPRSPSPE-PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK 604 Query: 454 SRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVG 513 + +R + + +R ++R + R++EKE+ER ++ + + E A+ S++ G Sbjct: 605 LAK---KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEG 661 Query: 514 QL 515 +L Sbjct: 662 RL 663 Score = 48.1 bits (113), Expect = 5e-05 Identities = 59/234 (25%), Positives = 74/234 (31%), Gaps = 54/234 (23%) Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPP-------AAPTNLPTPP----------- 799 T IS PN S G + SV GS+ P + ++P+P Sbjct: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 176 Query: 800 ----VTQPVSLLGTQGVAPGPVIGL----QAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 851 QP +L GV P P Q P+ G + + P P P+ Sbjct: 177 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQ--- 233 Query: 852 PLMPPRPMPPHMMHRGP------PPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP 905 P P P+P + + P PP P PPPH P PP P G P Sbjct: 234 PQAPTAPVPHTHIQQAPALHPQRPPSPH----PPPH--PSPHPPLQPLTGSAGQPSA--- 284 Query: 906 GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 QPP Q P P + Q Q PP PP Q Q Sbjct: 285 ----------PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 328 Score = 37.7 bits (86), Expect = 0.062 Identities = 59/284 (20%), Positives = 96/284 (33%), Gaps = 19/284 (6%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSS-EPPTQATPNSVPAVPQLPSSDAFAAVAQ-- 191 A+ +P+ E++ ++ + P SS + + S V + SS + Q Sbjct: 39 ASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE 98 Query: 192 --LFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAA-- 247 T + + Q+ +P SP+ + +++ + + P + + Sbjct: 99 KVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 158 Query: 248 --FPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA 305 P P+ + + +P A++ + T A ++ P P P T A Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSAT 217 Query: 306 AAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQM 365 A P SP QAP P +T Q P+ P H P P Sbjct: 218 AVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PSPHPPLQ 273 Query: 366 PGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKP 409 P G P P AQP + P P S QA PL Q P Sbjct: 274 PLTGSAGQPSAPSHAQPPLHGQGP---PGPHSLQA--GPLLQHP 312 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 96.3 bits (238), Expect = 1e-19 Identities = 105/378 (27%), Positives = 132/378 (34%), Gaps = 78/378 (20%) Query: 617 EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKP-------------LP 663 EG DS ++N + PK + + T P P P+ L Sbjct: 684 EGESSDSRSVNDEGSSDPKDIDQD--------NRSTSPSIPSPQDNESDSDSSAQQQMLQ 735 Query: 664 VPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPP 723 P + P +T P PP P P G PP G P P P P P Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP- 794 Query: 724 FLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMY 783 + P P PP P PP P PH PP+ P S + +A S ++ Sbjct: 795 ---VPHTHIQQAPALHPQRPPSPHPPP--HPSPH-PPLQ-PLTGSAGQPSAPSHAQPPLH 847 Query: 784 GSAVP---------------PAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLL 828 G P P P LP P +Q + LGT A P LQ P Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLP----- 901 Query: 829 GARPGLIPLQRPP---GMPP-----PHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 880 A + Q+PP +PP PH++ P P +P H+ PP G P P Sbjct: 902 -ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSP 956 Query: 881 HGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ--PQQQPQPQAPQQPQ 938 M PP P ++P + L P P PP Q PQ QP P +P QP Sbjct: 957 FSMNANLPP-PPALKP--LSSLSTHHPPSAHP--------PPLQLMPQSQPLPSSPAQPP 1005 Query: 939 --QQQQQQPPPSQQPPPT 954 Q Q PPP PPT Sbjct: 1006 GLTQSQNLPPPPASHPPT 1023 Score = 92.4 bits (228), Expect = 2e-18 Identities = 129/507 (25%), Positives = 179/507 (35%), Gaps = 112/507 (22%) Query: 646 GAETSHTEPVSPIPKPLPVPVPPI-------PVPAPITVPPPQVPPHQPGPPVVGALQPP 698 G+ T+ P P PVP I P P PPP PH P P+ G+ P Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP 836 Query: 699 AFT----PPL-GIPPPG-----FGPGVPPPPPPPPF-LRPGFNPMHLPPGFLP------- 740 + PPL G PPG GP + P PP PF L P + P G P Sbjct: 837 SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Query: 741 --------------------PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV 780 P PP P+ P PPP TP +P + SG S Sbjct: 897 SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS- 955 Query: 781 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQ---GVAPGPVIGLQAPSTGLLGARPGLIPL 837 P + NLP PP +P+S L T P P L P PL Sbjct: 956 -------PFSMNANLPPPPALKPLSSLSTHHPPSAHPPP-----------LQLMPQSQPL 997 Query: 838 QRPPGMPPPHLQRFPLMPPRPM-PPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF-VR 895 P PP Q L PP PP +H+ P P FA + PF P GP + Sbjct: 998 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--FA-------QHPFVPGGPPPIT 1048 Query: 896 PGGMPGLGGPGPGPG-------------GPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 942 P P P GPG G G P P Q + +A ++ + Sbjct: 1049 PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPES 1106 Query: 943 QQPPP-SQQPPPT-------QQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERY 994 PPP S P PT Q +F + +NS + + G+++ RE Sbjct: 1107 PPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-- 1164 Query: 995 GNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR 1054 + + + R+ + R +R++ ++ +ER R R+ ER ++ S E Sbjct: 1165 ----EAIEKAKREAEQKAREEREREKEKE-KEREREREREREAERAAKASSSAHEGR--- 1216 Query: 1055 GKEKPEVTDRAGGNKTVEPPISQVGNV 1081 P+++ + EPP + + V Sbjct: 1217 -LSDPQLSGPGHMRPSFEPPPTTIAAV 1242 Score = 53.5 bits (127), Expect = 1e-06 Identities = 99/422 (23%), Positives = 144/422 (34%), Gaps = 77/422 (18%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 213 SP PP S PP Q S PS+ + A Q G Q Q P Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQ----PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868 Query: 214 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 273 PQ L Q A L T+P + P Q ++ P A Sbjct: 869 PQPFGLP----PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 924 Query: 274 VEESKKEDTTAVTTT-APAA----------------AVPPAPTATVPAAAA----PAAAS 312 + K TT + AP A A P P A P ++ P +A Sbjct: 925 MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 984 Query: 313 PPP----PQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGF 368 PPP PQ+ P Q P TQ QN+ P +H P PP Q P Sbjct: 985 PPPLQLMPQSQ-PLPSSPAQPPGLTQSQNLP---PPPASHPPTGLHQVAPQPPFAQHPFV 1040 Query: 369 GLLPTPPFPPM--------------AQPVIP---------------PTPPVQQPFQASFQ 399 P P PP AQP P P VQ +A Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100 Query: 400 AQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSR------SASRSPKRRRSRSGSR 453 A+ EP + P + E P + + H S + + S +R+ +GS+ Sbjct: 1101 AE-EPESPPPPPRSPSPE-PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK 1158 Query: 454 SRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVG 513 + +R + + +R ++R + R++EKE+ER ++ + + E A+ S++ G Sbjct: 1159 LAK---KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEG 1215 Query: 514 QL 515 +L Sbjct: 1216 RL 1217 Score = 48.1 bits (113), Expect = 5e-05 Identities = 59/234 (25%), Positives = 74/234 (31%), Gaps = 54/234 (23%) Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPP-------AAPTNLPTPP----------- 799 T IS PN S G + SV GS+ P + ++P+P Sbjct: 671 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 730 Query: 800 ----VTQPVSLLGTQGVAPGPVIGL----QAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 851 QP +L GV P P Q P+ G + + P P P+ Sbjct: 731 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQ--- 787 Query: 852 PLMPPRPMPPHMMHRGP------PPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP 905 P P P+P + + P PP P PPPH P PP P G P Sbjct: 788 PQAPTAPVPHTHIQQAPALHPQRPPSPH----PPPH--PSPHPPLQPLTGSAGQPSA--- 838 Query: 906 GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 QPP Q P P + Q Q PP PP Q Q Sbjct: 839 ----------PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Score = 37.7 bits (86), Expect = 0.062 Identities = 59/284 (20%), Positives = 96/284 (33%), Gaps = 19/284 (6%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSS-EPPTQATPNSVPAVPQLPSSDAFAAVAQ-- 191 A+ +P+ E++ ++ + P SS + + S V + SS + Q Sbjct: 593 ASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE 652 Query: 192 --LFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAA-- 247 T + + Q+ +P SP+ + +++ + + P + + Sbjct: 653 KVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 712 Query: 248 --FPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA 305 P P+ + + +P A++ + T A ++ P P P T A Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSAT 771 Query: 306 AAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQM 365 A P SP QAP P +T Q P+ P H P P Sbjct: 772 AVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PSPHPPLQ 827 Query: 366 PGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKP 409 P G P P AQP + P P S QA PL Q P Sbjct: 828 PLTGSAGQPSAPSHAQPPLHGQGP---PGPHSLQA--GPLLQHP 866 Score = 31.2 bits (69), Expect = 5.8 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%) Query: 988 ENDRERYGNRNDDRDNSNRDR-REWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRES 1046 + D+E+ +R+ DR+ RD+ RE P R + +N S H + E D+ + + Sbjct: 8 DKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDE-DNDNNSA 66 Query: 1047 RREKEEARGKEKP 1059 E+ + K+KP Sbjct: 67 TAEESTKKNKKKP 79 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 96.3 bits (238), Expect = 1e-19 Identities = 105/378 (27%), Positives = 132/378 (34%), Gaps = 78/378 (20%) Query: 617 EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKP-------------LP 663 EG DS ++N + PK + + T P P P+ L Sbjct: 684 EGESSDSRSVNDEGSSDPKDIDQD--------NRSTSPSIPSPQDNESDSDSSAQQQMLQ 735 Query: 664 VPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPP 723 P + P +T P PP P P G PP G P P P P P Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP- 794 Query: 724 FLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMY 783 + P P PP P PP P PH PP+ P S + +A S ++ Sbjct: 795 ---VPHTHIQQAPALHPQRPPSPHPPP--HPSPH-PPLQ-PLTGSAGQPSAPSHAQPPLH 847 Query: 784 GSAVP---------------PAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLL 828 G P P P LP P +Q + LGT A P LQ P Sbjct: 848 GQGPPGPHSLQAGPLLQHPGPPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLP----- 901 Query: 829 GARPGLIPLQRPP---GMPP-----PHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 880 A + Q+PP +PP PH++ P P +P H+ PP G P P Sbjct: 902 -ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSP 956 Query: 881 HGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQ--PQQQPQPQAPQQPQ 938 M PP P ++P + L P P PP Q PQ QP P +P QP Sbjct: 957 FSMNANLPP-PPALKP--LSSLSTHHPPSAHP--------PPLQLMPQSQPLPSSPAQPP 1005 Query: 939 --QQQQQQPPPSQQPPPT 954 Q Q PPP PPT Sbjct: 1006 GLTQSQNLPPPPASHPPT 1023 Score = 92.4 bits (228), Expect = 2e-18 Identities = 129/507 (25%), Positives = 179/507 (35%), Gaps = 112/507 (22%) Query: 646 GAETSHTEPVSPIPKPLPVPVPPI-------PVPAPITVPPPQVPPHQPGPPVVGALQPP 698 G+ T+ P P PVP I P P PPP PH P P+ G+ P Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQP 836 Query: 699 AFT----PPL-GIPPPG-----FGPGVPPPPPPPPF-LRPGFNPMHLPPGFLP------- 740 + PPL G PPG GP + P PP PF L P + P G P Sbjct: 837 SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Query: 741 --------------------PGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSV 780 P PP P+ P PPP TP +P + SG S Sbjct: 897 SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS- 955 Query: 781 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQ---GVAPGPVIGLQAPSTGLLGARPGLIPL 837 P + NLP PP +P+S L T P P L P PL Sbjct: 956 -------PFSMNANLPPPPALKPLSSLSTHHPPSAHPPP-----------LQLMPQSQPL 997 Query: 838 QRPPGMPPPHLQRFPLMPPRPM-PPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF-VR 895 P PP Q L PP PP +H+ P P FA + PF P GP + Sbjct: 998 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--FA-------QHPFVPGGPPPIT 1048 Query: 896 PGGMPGLGGPGPGPG-------------GPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 942 P P P GPG G G P P Q + +A ++ + Sbjct: 1049 PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQIKEEALDDAEEPES 1106 Query: 943 QQPPP-SQQPPPT-------QQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERY 994 PPP S P PT Q +F + +NS + + G+++ RE Sbjct: 1107 PPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-- 1164 Query: 995 GNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEAR 1054 + + + R+ + R +R++ ++ +ER R R+ ER ++ S E Sbjct: 1165 ----EAIEKAKREAEQKAREEREREKEKE-KEREREREREREAERAAKASSSAHEGR--- 1216 Query: 1055 GKEKPEVTDRAGGNKTVEPPISQVGNV 1081 P+++ + EPP + + V Sbjct: 1217 -LSDPQLSGPGHMRPSFEPPPTTIAAV 1242 Score = 53.5 bits (127), Expect = 1e-06 Identities = 99/422 (23%), Positives = 144/422 (34%), Gaps = 77/422 (18%) Query: 154 SPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK 213 SP PP S PP Q S PS+ + A Q G Q Q P Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQ----PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868 Query: 214 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 273 PQ L Q A L T+P + P Q ++ P A Sbjct: 869 PQPFGLP----PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 924 Query: 274 VEESKKEDTTAVTTT-APAA----------------AVPPAPTATVPAAAA----PAAAS 312 + K TT + AP A A P P A P ++ P +A Sbjct: 925 MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 984 Query: 313 PPP----PQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGF 368 PPP PQ+ P Q P TQ QN+ P +H P PP Q P Sbjct: 985 PPPLQLMPQSQ-PLPSSPAQPPGLTQSQNLP---PPPASHPPTGLHQVAPQPPFAQHPFV 1040 Query: 369 GLLPTPPFPPM--------------AQPVIP---------------PTPPVQQPFQASFQ 399 P P PP AQP P P VQ +A Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDD 1100 Query: 400 AQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSR------SASRSPKRRRSRSGSR 453 A+ EP + P + E P + + H S + + S +R+ +GS+ Sbjct: 1101 AE-EPESPPPPPRSPSPE-PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK 1158 Query: 454 SRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVG 513 + +R + + +R ++R + R++EKE+ER ++ + + E A+ S++ G Sbjct: 1159 LAK---KREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEG 1215 Query: 514 QL 515 +L Sbjct: 1216 RL 1217 Score = 48.1 bits (113), Expect = 5e-05 Identities = 59/234 (25%), Positives = 74/234 (31%), Gaps = 54/234 (23%) Query: 758 TPPISIPNLVSGARGNAESGDSVKMYGSAVPP-------AAPTNLPTPP----------- 799 T IS PN S G + SV GS+ P + ++P+P Sbjct: 671 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQ 730 Query: 800 ----VTQPVSLLGTQGVAPGPVIGL----QAPSTGLLGARPGLIPLQRPPGMPPPHLQRF 851 QP +L GV P P Q P+ G + + P P P+ Sbjct: 731 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQ--- 787 Query: 852 PLMPPRPMPPHMMHRGP------PPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP 905 P P P+P + + P PP P PPPH P PP P G P Sbjct: 788 PQAPTAPVPHTHIQQAPALHPQRPPSPH----PPPH--PSPHPPLQPLTGSAGQPSA--- 838 Query: 906 GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 QPP Q P P + Q Q PP PP Q Q Sbjct: 839 ----------PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Score = 37.7 bits (86), Expect = 0.062 Identities = 59/284 (20%), Positives = 96/284 (33%), Gaps = 19/284 (6%) Query: 135 AAGTSNAAPVAENVTNNEGSPPPPVKVSS-EPPTQATPNSVPAVPQLPSSDAFAAVAQ-- 191 A+ +P+ E++ ++ + P SS + + S V + SS + Q Sbjct: 593 ASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQRE 652 Query: 192 --LFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAA-- 247 T + + Q+ +P SP+ + +++ + + P + + Sbjct: 653 KVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 712 Query: 248 --FPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAA 305 P P+ + + +P A++ + T A ++ P P P T A Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSAT 771 Query: 306 AAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQM 365 A P SP QAP P +T Q P+ P H P P Sbjct: 772 AVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PSPHPPLQ 827 Query: 366 PGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKP 409 P G P P AQP + P P S QA PL Q P Sbjct: 828 PLTGSAGQPSAPSHAQPPLHGQGP---PGPHSLQA--GPLLQHP 866 Score = 31.2 bits (69), Expect = 5.8 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%) Query: 988 ENDRERYGNRNDDRDNSNRDR-REWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRES 1046 + D+E+ +R+ DR+ RD+ RE P R + +N S H + E D+ + + Sbjct: 8 DKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDE-DNDNNSA 66 Query: 1047 RREKEEARGKEKP 1059 E+ + K+KP Sbjct: 67 TAEESTKKNKKKP 79 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 95.9 bits (237), Expect = 2e-19 Identities = 103/343 (30%), Positives = 126/343 (36%), Gaps = 71/343 (20%) Query: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713 P P P P P+ + P P+ P PH P PP + P TP + + P P Sbjct: 320 PPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP----P 375 Query: 714 GVPPPPPPPPFLRPGF-----NPMHLPPGFLPPGPPPPITPPVSIPPPHTP---PISIPN 765 V P P + P F P+ +P +P P P + P PP P P +PN Sbjct: 376 PVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPN 435 Query: 766 LVSGARGNAESGDSVKMYGSAVPPAAPT----NLPTPPVTQPVSLLGTQGV--------- 812 S PP P P PP + LG G Sbjct: 436 SFS------------------QPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477 Query: 813 ---APGPVIGLQAPSTGLLGARPGLIPLQRP-----PGMPPPHLQRFPLMP-PRPMPPHM 863 +P P P T L + P +P Q P PG + P+ P RP+ P + Sbjct: 478 EQRSPPPP---PPPPTLLNSSHP--VPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPAL 532 Query: 864 MHRGPPPGPGG---FAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG----PGPGGPEDRD 916 PPGP G F+ P + PP PF+ G P L GP P Sbjct: 533 Q----PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPP 588 Query: 917 GRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 Q PQQPQQQP PQ QP Q QPPP QPPP Q PQ Sbjct: 589 PHQPQPQQPQQQPPPQ--HQPPHQPPHQPPPQHQPPP-QHPPQ 628 Score = 46.6 bits (109), Expect = 1e-04 Identities = 71/301 (23%), Positives = 100/301 (33%), Gaps = 53/301 (17%) Query: 156 PPPVKVSSEPPTQATPNSV----PAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211 P P + PP TP + P PQ P + + F+ T +Q L Sbjct: 353 PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKN---IHINPHFKGTVVTPVQVPLLPVPSQ 409 Query: 212 PKP-----QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFD 266 P+P + P + P P + + PPP Q Sbjct: 410 PRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQ------------- 456 Query: 267 YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDG 326 D +P + S + + + PP P T+ ++ P P PF PG Sbjct: 457 -DRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSP---LPFTQPGPA 512 Query: 327 M----QQPAYTQHQNMDQF--QPRMMGIQQDPMHHQVP--------LPPNGQM---PGFG 369 QQP + + + + P +GI +H P +PP PG Sbjct: 513 FNQQGQQPVFPRERPVRPALQPPGPVGI----LHFSQPGSATTRPFIPPRQPFLPGPGQP 568 Query: 370 LLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQ---QEMEVEQPCIQEVKR 426 LPT P + P+ PP PP QP Q Q P Q PHQ Q QP Q + Sbjct: 569 FLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ 628 Query: 427 H 427 H Sbjct: 629 H 629 Score = 45.1 bits (105), Expect = 4e-04 Identities = 87/352 (24%), Positives = 114/352 (32%), Gaps = 63/352 (17%) Query: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQ------LFQTTQGQQL---QQIL 205 P PP P PNS P+LP D + A F G+ L Sbjct: 420 PGPPEFPQHTPGP--VPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477 Query: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265 + PP P P L N+ + Q TQP AF Q+ F ++ R Sbjct: 478 EQRSPPPPPPPPTLLNSS----HPVPTQSPLPFTQPGP---AFNQQGQQPVFPRERPVRP 530 Query: 266 DYDDEPEAVEESKKEDTTAVTTTA---------PAAAVPPAPTATVPAAAAPAAASPPPP 316 P V + TT P P PT T P P PPP Sbjct: 531 ALQP-PGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPP 589 Query: 317 -----QAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371 Q P P Q P HQ Q QP Q P HQ + + Sbjct: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ-----HHHHHHHLSV 644 Query: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQ------------NEPLTQKPHQQEMEV--- 416 P PP PM+QP P QP +S + Q ++ ++++P QQ Sbjct: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704 Query: 417 -----EQPCIQEVKRHMSDNRKSRSRSASRSP-----KRRRSRSGSRSRRSR 458 E P MS +R S + SA P R+ +GSRS + + Sbjct: 705 NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGK 756 Score = 37.0 bits (84), Expect = 0.11 Identities = 24/45 (53%), Positives = 27/45 (60%), Gaps = 5/45 (11%) Query: 370 LLPT-PPFPPMAQPVIPPTPPVQQPFQASFQAQN-EPL--TQKPH 410 LLPT PP P A P PP PP QQP ++ FQ Q +PL Q PH Sbjct: 308 LLPTQPPVVPQAPPP-PPPPPQQQPIRSLFQPQPLQPLLPVQHPH 351 >gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] Length = 2240 Score = 93.6 bits (231), Expect = 9e-19 Identities = 146/515 (28%), Positives = 196/515 (38%), Gaps = 116/515 (22%) Query: 677 VPPPQVPPHQPGPPVVGALQP-PAFTPPLGIPPPGF-GPGVPPPPPPPPFLRPGFNPMHL 734 +PPP PP G +P P G+ P F GP P PP P + P Sbjct: 1736 LPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGP 1795 Query: 735 PPGFL--PPGPPPPITPPVSIPPPHTPPIS-IPNLVSGARGNAESG-------DSVKMYG 784 PP GP P + PPP+ P+ + G RG A S K Sbjct: 1796 PPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREF 1855 Query: 785 SAVPPAAPTNLPTP-PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGM 843 P T P T+ LG++G AP G + RP L L+ P G Sbjct: 1856 QDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQR---------RPLLSQLKGPRGG 1906 Query: 844 PPPHL---QRFPLMPPR----PMPPHMMH----RGPPP----GPGGFA---MPPPHGMKG 885 PPP QR P PP P PH RGP P GP G A MP P G++ Sbjct: 1907 PPPSQFGGQRGP--PPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQP 1964 Query: 886 P--------FPPHGPFVR---PGGMPGLGGPGPGPGGPEDRDGR----QQPPQQPQQQPQ 930 PP R P GL G P E R Q PQ + P+ Sbjct: 1965 QQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPR 2024 Query: 931 P--QAPQQPQQQQQQQ-----PPPSQQPPPTQQQPQ--------QFR----NDNRQQFNS 971 P + P P Q ++ + PP + Q P+ FR ++ R Q Sbjct: 2025 PLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFE 2084 Query: 972 GRDQERF---------------GRRSFGNRVENDRERYGNRNDDRD-----NSNRDR--- 1008 GR +ERF GR S R E +R R +R D D + +RD+ Sbjct: 2085 GRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSS 2144 Query: 1009 REWGR---RSPDRDRHRDLE-----ERNRRSSGHRDRERD---SRDRESRREKEEARGKE 1057 R+W R RS +RDR R+ + +R+R S +R+RERD RDR RE++ + ++ Sbjct: 2145 RDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARD 2204 Query: 1058 KPEVTDRAGGNKTVE------PPISQVGNVDTASE 1086 + DR +K+ E P S+ + TAS+ Sbjct: 2205 RERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239 Score = 49.7 bits (117), Expect = 2e-05 Identities = 25/68 (36%), Positives = 36/68 (52%) Query: 430 DNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERE 489 + R + RS +R R+R R RR RSRSR RDR + R R ++R+DR K +E Sbjct: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219 Query: 490 RRQKGLPQ 497 + P+ Sbjct: 2220 SARDPKPE 2227 Score = 48.1 bits (113), Expect = 5e-05 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%) Query: 385 PPTPPVQQPF---QASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNR---KSRSRS 438 P P+++P +AS + E + +E + ++P + R +R ++R RS Sbjct: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154 Query: 439 ASRSPKRR----------RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKER 488 A+R +R R RS +R R RR R RSR R R ++R +ER K+R Sbjct: 2155 ANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDR 2214 Query: 489 ERRQKGLPQVKPETA 503 + ++ KPE + Sbjct: 2215 SKSKESARDPKPEAS 2229 Score = 43.9 bits (102), Expect = 9e-04 Identities = 40/183 (21%), Positives = 68/183 (37%), Gaps = 6/183 (3%) Query: 947 PSQQPPPTQQQPQQFRNDNRQQFNSGRDQE------RFGRRSFGNRVENDRERYGNRNDD 1000 P + PPP QQ R RQ + R ++ R GRRS +E+ E D Sbjct: 47 PLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATD 106 Query: 1001 RDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPE 1060 + ++ E + + + R +S + + D D S + + KE Sbjct: 107 AETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQN 166 Query: 1061 VTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSA 1120 R + E P+ + + E+G +E + S+ + S EPE D G Sbjct: 167 RLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVV 226 Query: 1121 AEA 1123 ++A Sbjct: 227 SQA 229 Score = 39.7 bits (91), Expect = 0.016 Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 58/353 (16%) Query: 149 TNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQ-------L 201 T GSPPPP + P + + PA P ++ AA A ++ L Sbjct: 1255 TTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPL 1314 Query: 202 QQILQTF-----------QQPP-----KPQSP--ALDNAVMAQ------VQAITAQLKTT 237 + ILQT ++PP PQ P ++ V A VQ K Sbjct: 1315 EHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDK 1374 Query: 238 PTQPSEQKAAFPPPEQ---KTAFDKKLLD---RFDYDDEPEAVEESKKE---DTTAVTTT 288 + E + P E+ + AFD +L++ R + + PEA ++E D T Sbjct: 1375 ALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETIL 1434 Query: 289 APA-AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347 A V P + P P A P QQ + + Q R + Sbjct: 1435 EEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLE 1494 Query: 348 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQ 407 Q++ + Q M F + PP + P + FQ Q+ ++P + Sbjct: 1495 EQEEALRQQ-RAAVGVSMAHFSVSDALMSPPPKSSL-----PKAELFQQEQQSADKPASL 1548 Query: 408 KPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR---------SPKRRRSRSG 451 P Q P ++ +R ++ + SR P+R SR G Sbjct: 1549 PPASQASNHRDP--RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGG 1599 Score = 38.1 bits (87), Expect = 0.047 Identities = 37/104 (35%), Positives = 43/104 (41%), Gaps = 22/104 (21%) Query: 870 PGPGGFAMPPPHGMK--GPFPPHGPFVRPG----GMPGLGGPG-PGPGGP---------E 913 PG G +PPP G K G PP PG GM GL GP PGP GP Sbjct: 1729 PGEGTAPLPPP-GQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIA 1787 Query: 914 DRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPP---SQQPPPT 954 DG + PP P + + P Q PPP S+ P P+ Sbjct: 1788 SNDGPRGPP--PARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPS 1829 Score = 35.0 bits (79), Expect = 0.40 Identities = 67/306 (21%), Positives = 110/306 (35%), Gaps = 42/306 (13%) Query: 104 SEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEG---------- 153 SED+ R+ +G K++I QP+++ + P +V + Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420 Query: 154 SPPPPVKVSS-----EPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTF 208 +K S +P + P P LP A A + +I Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGI-------------KISSVH 467 Query: 209 QQP-PKPQSPALDNAVM--AQVQAITAQL---KTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 ++P P+ + + AV+ A+ +A+ + +TP+ S+ PE+ A LL Sbjct: 468 KRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLL 527 Query: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--PPAPTATVP---AAAAPAAASPPPPQ 317 + +D EE + T P +AV PAP VP + A AAA+P + Sbjct: 528 YKSTKEDRRS--EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKK 585 Query: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMG-IQQDPMHHQVPLPPNGQMPGFGLLPTPPF 376 P GF G ++P + + R G P + + G P P Sbjct: 586 PPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPS 645 Query: 377 PPMAQP 382 PMA P Sbjct: 646 VPMASP 651 Score = 30.8 bits (68), Expect = 7.6 Identities = 42/149 (28%), Positives = 51/149 (34%), Gaps = 26/149 (17%) Query: 660 KPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPP 719 +P VP P A TVP + P + P+ A + TPP G PPPP Sbjct: 1219 QPEEADVPAYPKVA--TVPQSEKKPSKY--PLCSADAAVSTTPP----------GSPPPP 1264 Query: 720 PPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAES--- 776 PP P P P+ L P P P T + T S + S E Sbjct: 1265 PPLP--EP---PVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQ 1319 Query: 777 ---GDSVKMYGSA-VPPAAPTNLPTPPVT 801 G SA PP + LP P T Sbjct: 1320 TLFGKKKSFDPSAREPPGSTAGLPQEPKT 1348 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 91.3 bits (225), Expect = 5e-18 Identities = 105/360 (29%), Positives = 125/360 (34%), Gaps = 58/360 (16%) Query: 623 SDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPV-PPIPVPAPITVPPPQ 681 + T D +P + + Q A+ E V P LP P PPI P P PP Q Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTP-GKPPAQ 317 Query: 682 VPPH---QPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGF 738 P H QPGP A QP T PL P P V PP P Sbjct: 318 QPGHEKSQPGPAKPPA-QPSGLTKPLAQQPGTVKPPVQPPGTTKP--------------- 361 Query: 739 LPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798 P P P PP P P + A+ + G A PP P P Sbjct: 362 -PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Query: 799 PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRP 858 QP L + APGP T + PG IP Q+ Q P PP Sbjct: 421 LAQQPG--LQSPAKAPGPT------KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 859 MPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG-MPGLGGPGPGPGGPEDRDG 917 +P PPP G A PPP + P P +PG P PGP P+ Sbjct: 473 LPGPAK---PPPQQPGPAKPPP---QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 918 RQQPPQQP------QQQPQPQAPQQPQQQ---------QQQQPP---PSQQPPPTQQQPQ 959 + P QQP QQP P P Q + QPP PS + PP+Q P+ Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 85.1 bits (209), Expect = 3e-16 Identities = 100/349 (28%), Positives = 119/349 (34%), Gaps = 75/349 (21%) Query: 660 KPLPVPVPPI----PVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGV 715 KP + PP+ P P P P + P Q G P + Q P + PPG G + Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE---KIKSQPPGTGKPI 258 Query: 716 PPPPPPP-------PFLRPGFNPMHLPPGFL-----PPGPPPPITPPVSIPPPHTPPISI 763 P P P R P + P P P PP+ P P PP Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318 Query: 764 PNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQP------VSLLGT-----QGV 812 P G G A PPA P+ L P QP V GT Q + Sbjct: 319 P------------GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366 Query: 813 APGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 872 P Q S +PG L +PPG+ + P P P P G P Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG-----KTPAQQPGPAKPPTQQVGTPKP- 420 Query: 873 GGFAMPPPHGMKGPFPPHGPFVRPGGMPGLG-------GPGP------GPGGPEDR-DGR 918 A P G++ P GP P PG G GPG GP P + G Sbjct: 421 --LAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 919 QQPPQQ-------PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 +PP Q P QQP P P QQ PP QQP P + PQQ Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKP--PSQQPGSTKPPPQQPGPAKPSPQQ 523 Score = 55.1 bits (131), Expect = 4e-07 Identities = 48/171 (28%), Positives = 61/171 (35%), Gaps = 28/171 (16%) Query: 655 VSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPV---------------------VG 693 +S P P P P PP P P P PPP PP P P + V Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460 Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRP-GFNPMHLPPGFLPPGPPPPITP--P 750 L+ A G+P PPP PP P P G H P PP P P+ P P Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520 Query: 751 VSIPPP---HTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798 + P H P + +L S N + K+ P + +N +P Sbjct: 2521 TTTQKPTDIHPKPTGL-SLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 52.8 bits (125), Expect = 2e-06 Identities = 72/328 (21%), Positives = 110/328 (33%), Gaps = 49/328 (14%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P+ ++ T S P K+ S+PP P P QT Q + Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT-----------------QTPQTDHAK 271 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 LQ + +PQ+ D + + +++ L + P +Q PP Q+ +K Sbjct: 272 LPLQ--RDASRPQTKQAD---IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 263 DRFDYDDEPEAVEESKKEDTTAV--------TTTAPAAAVPPAPTATVPAAAAPAAASPP 314 +P + + + V TT PA + PA + ++ P Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386 Query: 315 PPQAPFGFPGDGM---QQPAYTQHQNMDQFQPRMMGIQ---QDPMHHQVPLPPNGQMPGF 368 P+A PG G QQP + P+ + Q Q P P Q PG Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446 Query: 369 GLLP-------------TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEME 415 G +P T P P +Q P PP QQP A Q + P QQ Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506 Query: 416 VEQPCIQEVKRHMSDNRKSRSRSASRSP 443 + P Q S + ++ S+ P Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Score = 48.5 bits (114), Expect = 3e-05 Identities = 50/175 (28%), Positives = 64/175 (36%), Gaps = 19/175 (10%) Query: 709 PGFGPGVPP-PPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLV 767 P P V P P PF R + P PP PPPP PP PPP PP + P Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436 Query: 768 SGARGNAESGDSVKMYGSAVPP-AAPTNLPTPPVTQ----PVSLLGTQGVAPGPVIGLQA 822 + V +A P A T L T V + PV+ + T P P Sbjct: 2437 ILPKKKLTVASPVT---TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493 Query: 823 PSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 877 PS + RP +PP P P + + P +P H P P G ++ Sbjct: 2494 PSGLVFTHRP---EPSKPPIAPKPVIPQLPTTTQKPTDIH-------PKPTGLSL 2538 Score = 45.8 bits (107), Expect = 2e-04 Identities = 87/411 (21%), Positives = 124/411 (30%), Gaps = 90/411 (21%) Query: 626 LNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPP- 684 L D +P P+ ++ TS SP P+ P P P+ PP Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705 Query: 685 --HQP---GPPVVGALQPPAFTPPLGIPPPGFGPGVPPP----------PPPPPFLRPGF 729 QP G P A QPP L P P P VP P P ++P Sbjct: 706 LVKQPTLHGSPSAKAKQPPE-ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764 Query: 730 NPMHLPPGFLPPGPP-------------PPITPPVSIPPPHTPPI----------SIPNL 766 + + P P PP+ + P PP +IP Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824 Query: 767 VSGARGNAESGDSVKMYGSAV---------PPAAPTNLPTPPVTQPVSLLGTQGVAPGPV 817 S ++ + G S + G P A T + P +P+ P P Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884 Query: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLM--------PPRPMPPHMMHRGPP 869 G P+ P Q P P +RF L +P P G Sbjct: 885 AGQTVPT-----------PQQSPK--PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931 Query: 870 PGPGGF------------AMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG 917 G G P PH GP P P P GP G Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991 Query: 918 RQQPPQQPQQQP-----QPQAPQQP---QQQQQQQPPPSQQPPPTQQQPQQ 960 + P ++ + P +P+A Q P + + +++PPP + +PQ+ Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042 Score = 44.7 bits (104), Expect = 5e-04 Identities = 79/346 (22%), Positives = 121/346 (34%), Gaps = 59/346 (17%) Query: 153 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVA--QLFQTTQGQQLQQILQTFQQ 210 GSP K E + + P + P P +PS A VA + Q + ++ + Sbjct: 714 GSPSAKAKQPPEADSLSKP-APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772 Query: 211 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTA-FDKKLLDRFDYDD 269 KP P+ A+ + T LKT +PS+ +FPP +K + FD K + R D Sbjct: 773 TTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAIPRPASDS 828 Query: 270 E----PEAVEESK-----------KEDTTAVTTTAP---------AAAVPPAPTATVPAA 305 + P ESK +E A T +P + PP P T Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888 Query: 306 AAPAAASPPPPQAPFGFP---GDGMQQPAYTQHQNMDQFQPRMMGI-------------- 348 SP P + F G P + ++ G Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948 Query: 349 --QQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP----PVQQPFQASFQAQN 402 Q P P P Q P PT PP + PP P PV++ +A + Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008 Query: 403 EPLTQKP---HQQEMEVEQPCIQEVKRHMSDNRKS-RSRSASRSPK 444 EP ++ + E E + P I++ K ++ +K+ +SPK Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK 1054 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/212 (26%), Positives = 76/212 (35%), Gaps = 58/212 (27%) Query: 633 IPKKPENEVAQNGGAETSHTE-PVSPIPKPLP----VPVPPIPV----PAPITVPPPQVP 683 +P K + ET E P S +P P +P P P I+ PP P Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409 Query: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 743 P P PP PPP PPPPPPP LPP P P Sbjct: 2410 PPPPPPP----------------PPP------PPPPPPP-----------LPP---PTSP 2433 Query: 744 PPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG---SAVPPAAPTNLPTPPV 800 P I P + P++ + A E+ ++ G + + AP +P P Sbjct: 2434 KPTILPKKKLTV--ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 Query: 801 TQPVSLLGTQ-------GVAPGPVIGLQAPST 825 + P L+ T +AP PVI Q P+T Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPVIP-QLPTT 2522 Score = 38.1 bits (87), Expect = 0.047 Identities = 49/204 (24%), Positives = 63/204 (30%), Gaps = 49/204 (24%) Query: 788 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH 847 PP++ LP L T G G + P++ L P + L P P P Sbjct: 2343 PPSSVIALPMK------EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL---PAKPRPF 2393 Query: 848 LQRFPL----MPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF---------- 893 + L PP P PP PPP P +PPP K P Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453 Query: 894 --------------VRPGGMP----GLGGPGPGPGGPEDRDG-----RQQPPQQPQQQPQ 930 +R G+P P P P P + P +P P+ Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513 Query: 931 PQAPQQPQQQQQQQPPPSQQPPPT 954 P PQ P Q+ P P PT Sbjct: 2514 PVIPQLPTTTQK---PTDIHPKPT 2534 Score = 37.0 bits (84), Expect = 0.11 Identities = 38/149 (25%), Positives = 53/149 (35%), Gaps = 31/149 (20%) Query: 269 DEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQ 328 + P +++ T + VPP T ++PA P QAP Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPAL----PTQAP--------- 3900 Query: 329 QPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 +YTQ + +Q Q H QV P P F + T F P QP P P Sbjct: 3901 -TSYTQQSHFEQ---------QTLYHQQVS--PYQTQPTFQAVATMSFTPQVQPTPTPQP 3948 Query: 389 PVQQPFQASFQAQNEPLTQKPHQQEMEVE 417 Q P +Q + QKP Q + +E Sbjct: 3949 SYQLP------SQMMVIQQKPRQTTLYLE 3971 Score = 36.6 bits (83), Expect = 0.14 Identities = 98/446 (21%), Positives = 130/446 (29%), Gaps = 128/446 (28%) Query: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPL-PVPVPPIPVPAPITVPPPQVP------PHQ 686 P KP + Q G A+ +P S P P P P P P T PP Q P Q Sbjct: 486 PAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 687 PGPPVVGALQPPAFTPPLG----IPPPGFGPGVPPPPPP--PPFLRPGFNP----MHLPP 736 P P A Q G + PP P PP P + P N +H+P Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603 Query: 737 ------------------GFLPPGPPPPIT---------------------PPVSIPPPH 757 GF P P +T P S P P Sbjct: 604 KANFNTCTECQTTVCSLCGF---NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660 Query: 758 --TPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPG 815 T P++ + VS + + K A P + P P P+ T +P Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKK---DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 816 PVIGLQAPSTGLLGARPGLIPLQRPPGMP--PPHLQRFPLMPPRPMPPHMM--------- 864 Q P L ++P PP P P + P+ +P P M+ Sbjct: 718 AK-AKQPPEADSL-SKPA------PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 865 -------------------HRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP 905 + PP A P FPP G V P + P Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS-----FPPTGEKVSPFDSKAIPRP 824 Query: 906 G--------PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPP---PT 954 PGP + P Q+ ++ + Q P+ + P S PP PT Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884 Query: 955 --------QQQPQQFRNDNRQQFNSG 972 QQ P+ R N G Sbjct: 885 AGQTVPTPQQSPKPQEQSRRFSLNLG 910 Score = 35.4 bits (80), Expect = 0.31 Identities = 75/358 (20%), Positives = 127/358 (35%), Gaps = 61/358 (17%) Query: 118 QKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPP------------VKVSSEP 165 + G +++ +Q + + +P + +GSP PP + S +P Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898 Query: 166 PTQA------------TPNSVPAVPQ-LPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 212 Q+ P S P PQ + F A +F Q ++ T Q P Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF-----SQASNLISTAGQ-P 952 Query: 213 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPP--------EQKTAFDKKLLDR 264 P S + A M Q A +Q T+ P A P P E K +KL + Sbjct: 953 GPHSQSGPGAPMKQAPA-PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK 1011 Query: 265 FDYDDEPEAVEESKK----EDTTAVTTTAPAAAVP------PAPTATVPAAAAPAAASPP 314 + + E KK +D+ ++T A +P P P +T P Sbjct: 1012 AEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSK 1071 Query: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQFQ--PRMMGIQQ-DPMHHQVPLPPNGQMPGFGLL 371 P P Q N+ F P + IQ+ ++ Q +GQ+ + Sbjct: 1072 DP------PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKM 1125 Query: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMS 429 P P P A P+ PT Q + + Q + + ++ + + E E+ +++VK +S Sbjct: 1126 PPAPSGPKASPMPVPTESSSQ--KTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181 Score = 34.7 bits (78), Expect = 0.52 Identities = 53/236 (22%), Positives = 78/236 (33%), Gaps = 25/236 (10%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPP-TQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQL 201 P + + S P K ++PP TP P P P + L Q Q Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSP 430 Query: 202 QQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKA--AFPPPEQKTAFDK 259 + + P + P A A +AQ +T PT+P Q A PPP+Q Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ-QTGPTKPPSQLPGPAKPPPQQ------ 483 Query: 260 KLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPA--AASPPPPQ 317 P + ++ +A + + P P PA +P ++ PP Q Sbjct: 484 -----------PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532 Query: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373 P G QQP+ + +P P+ P Q P GL T Sbjct: 533 QP-GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587 Score = 33.9 bits (76), Expect = 0.89 Identities = 43/206 (20%), Positives = 71/206 (34%), Gaps = 23/206 (11%) Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVP---PA 297 P +Q+ P P+Q+ D D P+++ + E + + P P P Sbjct: 210 PLQQQPPKPIPKQQGPGR----DPLQQDGTPKSISSQQPEK---IKSQPPGTGKPIQGPT 262 Query: 298 PTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQV 357 T A P PQ +Q + +++ +P + + P+ Sbjct: 263 QTPQTDHAKLPLQRDASRPQT---------KQADIVRGESV---KPSLPSPSKPPIQQPT 310 Query: 358 PLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVE 417 P P Q PG P P AQP P QQP Q P T KP Q + Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ-PPGTTKPPAQPLGPA 369 Query: 418 QPCIQEVKRHMSDNRKSRSRSASRSP 443 +P Q+ + + ++ ++ P Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPP 395 Score = 33.9 bits (76), Expect = 0.89 Identities = 16/39 (41%), Positives = 17/39 (43%), Gaps = 7/39 (17%) Query: 920 QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 QPP P P P P P PPP PPPT +P Sbjct: 2404 QPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKP 2435 Score = 33.1 bits (74), Expect = 1.5 Identities = 56/285 (19%), Positives = 97/285 (34%), Gaps = 31/285 (10%) Query: 118 QKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAV 177 Q+ G K QP + + PV++ + PP + +PP+Q P ++ Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI--C 589 Query: 178 PQLPSSDAFAAV---AQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQ---AIT 231 P +++ V A T+ Q L F P P + + Q A+ Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN--PNPHLTEVKEWLCLNCQMKRALG 647 Query: 232 AQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV--TTTA 289 L P+ P + K P +A K P+ + S K+D + A Sbjct: 648 GDLAPVPSSP-QPKLKTAPVTTTSAVSK---------SSPQPQQTSPKKDAAPKQDLSKA 697 Query: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 349 P PP +P+A + PP+A D + +PA + ++ Q + Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEA------DSLSKPAPPKEPSVPSEQDKAPVAD 751 Query: 350 QDPMHHQVPLPPNGQMPGFGLLPTPPFPP---MAQPVIPPTPPVQ 391 P ++ P + P P +Q TPP++ Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796 Score = 32.7 bits (73), Expect = 2.0 Identities = 35/179 (19%), Positives = 77/179 (43%), Gaps = 31/179 (17%) Query: 924 QPQQQPQPQAPQQPQQQQQQQP---------PPSQQPPPTQQQPQQFRNDNRQQFNSGRD 974 + + QP +P+QP+ Q++ Q + +++ F+ D++Q S +D Sbjct: 1433 EKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKD 1492 Query: 975 QERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSS-- 1032 + + F + + RE Y + + ++ N SP + +R RR+S Sbjct: 1493 HKE--KSEFVDDITTRREPYDSVEESSESEN---------SP-------VPQRKRRTSVG 1534 Query: 1033 GHRDRERDSRDRESRREKEEARGKEKPEVT--DRAGGNKTVEPPISQVGNVDTASELEK 1089 E D + E+E+ K+ E++ + A G++ E +Q+ + +++E +K Sbjct: 1535 SSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK 1593 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 91.3 bits (225), Expect = 5e-18 Identities = 105/360 (29%), Positives = 125/360 (34%), Gaps = 58/360 (16%) Query: 623 SDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPV-PPIPVPAPITVPPPQ 681 + T D +P + + Q A+ E V P LP P PPI P P PP Q Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTP-GKPPAQ 317 Query: 682 VPPH---QPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGF 738 P H QPGP A QP T PL P P V PP P Sbjct: 318 QPGHEKSQPGPAKPPA-QPSGLTKPLAQQPGTVKPPVQPPGTTKP--------------- 361 Query: 739 LPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798 P P P PP P P + A+ + G A PP P P Sbjct: 362 -PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Query: 799 PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRP 858 QP L + APGP T + PG IP Q+ Q P PP Sbjct: 421 LAQQPG--LQSPAKAPGPT------KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 859 MPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGG-MPGLGGPGPGPGGPEDRDG 917 +P PPP G A PPP + P P +PG P PGP P+ Sbjct: 473 LPGPAK---PPPQQPGPAKPPP---QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 918 RQQPPQQP------QQQPQPQAPQQPQQQ---------QQQQPP---PSQQPPPTQQQPQ 959 + P QQP QQP P P Q + QPP PS + PP+Q P+ Sbjct: 527 TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586 Score = 85.1 bits (209), Expect = 3e-16 Identities = 100/349 (28%), Positives = 119/349 (34%), Gaps = 75/349 (21%) Query: 660 KPLPVPVPPI----PVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGV 715 KP + PP+ P P P P + P Q G P + Q P + PPG G + Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE---KIKSQPPGTGKPI 258 Query: 716 PPPPPPP-------PFLRPGFNPMHLPPGFL-----PPGPPPPITPPVSIPPPHTPPISI 763 P P P R P + P P P PP+ P P PP Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318 Query: 764 PNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQP------VSLLGT-----QGV 812 P G G A PPA P+ L P QP V GT Q + Sbjct: 319 P------------GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366 Query: 813 APGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 872 P Q S +PG L +PPG+ + P P P P G P Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG-----KTPAQQPGPAKPPTQQVGTPKP- 420 Query: 873 GGFAMPPPHGMKGPFPPHGPFVRPGGMPGLG-------GPGP------GPGGPEDR-DGR 918 A P G++ P GP P PG G GPG GP P + G Sbjct: 421 --LAQQP--GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Query: 919 QQPPQQ-------PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 +PP Q P QQP P P QQ PP QQP P + PQQ Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKP--PSQQPGSTKPPPQQPGPAKPSPQQ 523 Score = 55.1 bits (131), Expect = 4e-07 Identities = 48/171 (28%), Positives = 61/171 (35%), Gaps = 28/171 (16%) Query: 655 VSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPV---------------------VG 693 +S P P P P PP P P P PPP PP P P + V Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460 Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRP-GFNPMHLPPGFLPPGPPPPITP--P 750 L+ A G+P PPP PP P P G H P PP P P+ P P Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520 Query: 751 VSIPPP---HTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798 + P H P + +L S N + K+ P + +N +P Sbjct: 2521 TTTQKPTDIHPKPTGL-SLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 52.8 bits (125), Expect = 2e-06 Identities = 72/328 (21%), Positives = 110/328 (33%), Gaps = 49/328 (14%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 P+ ++ T S P K+ S+PP P P QT Q + Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT-----------------QTPQTDHAK 271 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 LQ + +PQ+ D + + +++ L + P +Q PP Q+ +K Sbjct: 272 LPLQ--RDASRPQTKQAD---IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 263 DRFDYDDEPEAVEESKKEDTTAV--------TTTAPAAAVPPAPTATVPAAAAPAAASPP 314 +P + + + V TT PA + PA + ++ P Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386 Query: 315 PPQAPFGFPGDGM---QQPAYTQHQNMDQFQPRMMGIQ---QDPMHHQVPLPPNGQMPGF 368 P+A PG G QQP + P+ + Q Q P P Q PG Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446 Query: 369 GLLP-------------TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEME 415 G +P T P P +Q P PP QQP A Q + P QQ Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506 Query: 416 VEQPCIQEVKRHMSDNRKSRSRSASRSP 443 + P Q S + ++ S+ P Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Score = 48.5 bits (114), Expect = 3e-05 Identities = 50/175 (28%), Positives = 64/175 (36%), Gaps = 19/175 (10%) Query: 709 PGFGPGVPP-PPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLV 767 P P V P P PF R + P PP PPPP PP PPP PP + P Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436 Query: 768 SGARGNAESGDSVKMYGSAVPP-AAPTNLPTPPVTQ----PVSLLGTQGVAPGPVIGLQA 822 + V +A P A T L T V + PV+ + T P P Sbjct: 2437 ILPKKKLTVASPVT---TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493 Query: 823 PSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 877 PS + RP +PP P P + + P +P H P P G ++ Sbjct: 2494 PSGLVFTHRP---EPSKPPIAPKPVIPQLPTTTQKPTDIH-------PKPTGLSL 2538 Score = 45.8 bits (107), Expect = 2e-04 Identities = 87/411 (21%), Positives = 124/411 (30%), Gaps = 90/411 (21%) Query: 626 LNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPP- 684 L D +P P+ ++ TS SP P+ P P P+ PP Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705 Query: 685 --HQP---GPPVVGALQPPAFTPPLGIPPPGFGPGVPPP----------PPPPPFLRPGF 729 QP G P A QPP L P P P VP P P ++P Sbjct: 706 LVKQPTLHGSPSAKAKQPPE-ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764 Query: 730 NPMHLPPGFLPPGPP-------------PPITPPVSIPPPHTPPI----------SIPNL 766 + + P P PP+ + P PP +IP Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824 Query: 767 VSGARGNAESGDSVKMYGSAV---------PPAAPTNLPTPPVTQPVSLLGTQGVAPGPV 817 S ++ + G S + G P A T + P +P+ P P Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884 Query: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLM--------PPRPMPPHMMHRGPP 869 G P+ P Q P P +RF L +P P G Sbjct: 885 AGQTVPT-----------PQQSPK--PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931 Query: 870 PGPGGF------------AMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDG 917 G G P PH GP P P P GP G Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991 Query: 918 RQQPPQQPQQQP-----QPQAPQQP---QQQQQQQPPPSQQPPPTQQQPQQ 960 + P ++ + P +P+A Q P + + +++PPP + +PQ+ Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042 Score = 44.7 bits (104), Expect = 5e-04 Identities = 79/346 (22%), Positives = 121/346 (34%), Gaps = 59/346 (17%) Query: 153 GSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVA--QLFQTTQGQQLQQILQTFQQ 210 GSP K E + + P + P P +PS A VA + Q + ++ + Sbjct: 714 GSPSAKAKQPPEADSLSKP-APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772 Query: 211 PPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTA-FDKKLLDRFDYDD 269 KP P+ A+ + T LKT +PS+ +FPP +K + FD K + R D Sbjct: 773 TTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAIPRPASDS 828 Query: 270 E----PEAVEESK-----------KEDTTAVTTTAP---------AAAVPPAPTATVPAA 305 + P ESK +E A T +P + PP P T Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888 Query: 306 AAPAAASPPPPQAPFGFP---GDGMQQPAYTQHQNMDQFQPRMMGI-------------- 348 SP P + F G P + ++ G Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948 Query: 349 --QQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP----PVQQPFQASFQAQN 402 Q P P P Q P PT PP + PP P PV++ +A + Sbjct: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008 Query: 403 EPLTQKP---HQQEMEVEQPCIQEVKRHMSDNRKS-RSRSASRSPK 444 EP ++ + E E + P I++ K ++ +K+ +SPK Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK 1054 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/212 (26%), Positives = 76/212 (35%), Gaps = 58/212 (27%) Query: 633 IPKKPENEVAQNGGAETSHTE-PVSPIPKPLP----VPVPPIPV----PAPITVPPPQVP 683 +P K + ET E P S +P P +P P P I+ PP P Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409 Query: 684 PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGP 743 P P PP PPP PPPPPPP LPP P P Sbjct: 2410 PPPPPPP----------------PPP------PPPPPPP-----------LPP---PTSP 2433 Query: 744 PPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG---SAVPPAAPTNLPTPPV 800 P I P + P++ + A E+ ++ G + + AP +P P Sbjct: 2434 KPTILPKKKLTV--ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 Query: 801 TQPVSLLGTQ-------GVAPGPVIGLQAPST 825 + P L+ T +AP PVI Q P+T Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPVIP-QLPTT 2522 Score = 38.1 bits (87), Expect = 0.047 Identities = 49/204 (24%), Positives = 63/204 (30%), Gaps = 49/204 (24%) Query: 788 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH 847 PP++ LP L T G G + P++ L P + L P P P Sbjct: 2343 PPSSVIALPMK------EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL---PAKPRPF 2393 Query: 848 LQRFPL----MPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF---------- 893 + L PP P PP PPP P +PPP K P Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453 Query: 894 --------------VRPGGMP----GLGGPGPGPGGPEDRDG-----RQQPPQQPQQQPQ 930 +R G+P P P P P + P +P P+ Sbjct: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513 Query: 931 PQAPQQPQQQQQQQPPPSQQPPPT 954 P PQ P Q+ P P PT Sbjct: 2514 PVIPQLPTTTQK---PTDIHPKPT 2534 Score = 37.0 bits (84), Expect = 0.11 Identities = 38/149 (25%), Positives = 53/149 (35%), Gaps = 31/149 (20%) Query: 269 DEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQ 328 + P +++ T + VPP T ++PA P QAP Sbjct: 3854 ERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPAL----PTQAP--------- 3900 Query: 329 QPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 +YTQ + +Q Q H QV P P F + T F P QP P P Sbjct: 3901 -TSYTQQSHFEQ---------QTLYHQQVS--PYQTQPTFQAVATMSFTPQVQPTPTPQP 3948 Query: 389 PVQQPFQASFQAQNEPLTQKPHQQEMEVE 417 Q P +Q + QKP Q + +E Sbjct: 3949 SYQLP------SQMMVIQQKPRQTTLYLE 3971 Score = 36.6 bits (83), Expect = 0.14 Identities = 98/446 (21%), Positives = 130/446 (29%), Gaps = 128/446 (28%) Query: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPL-PVPVPPIPVPAPITVPPPQVP------PHQ 686 P KP + Q G A+ +P S P P P P P P T PP Q P Q Sbjct: 486 PAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 687 PGPPVVGALQPPAFTPPLG----IPPPGFGPGVPPPPPP--PPFLRPGFNP----MHLPP 736 P P A Q G + PP P PP P + P N +H+P Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603 Query: 737 ------------------GFLPPGPPPPIT---------------------PPVSIPPPH 757 GF P P +T P S P P Sbjct: 604 KANFNTCTECQTTVCSLCGF---NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660 Query: 758 --TPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPG 815 T P++ + VS + + K A P + P P P+ T +P Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKK---DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 816 PVIGLQAPSTGLLGARPGLIPLQRPPGMP--PPHLQRFPLMPPRPMPPHMM--------- 864 Q P L ++P PP P P + P+ +P P M+ Sbjct: 718 AK-AKQPPEADSL-SKPA------PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 865 -------------------HRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP 905 + PP A P FPP G V P + P Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS-----FPPTGEKVSPFDSKAIPRP 824 Query: 906 G--------PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPP---PT 954 PGP + P Q+ ++ + Q P+ + P S PP PT Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884 Query: 955 --------QQQPQQFRNDNRQQFNSG 972 QQ P+ R N G Sbjct: 885 AGQTVPTPQQSPKPQEQSRRFSLNLG 910 Score = 35.4 bits (80), Expect = 0.31 Identities = 75/358 (20%), Positives = 127/358 (35%), Gaps = 61/358 (17%) Query: 118 QKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPP------------VKVSSEP 165 + G +++ +Q + + +P + +GSP PP + S +P Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898 Query: 166 PTQA------------TPNSVPAVPQ-LPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPP 212 Q+ P S P PQ + F A +F Q ++ T Q P Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF-----SQASNLISTAGQ-P 952 Query: 213 KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPP--------EQKTAFDKKLLDR 264 P S + A M Q A +Q T+ P A P P E K +KL + Sbjct: 953 GPHSQSGPGAPMKQAPA-PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK 1011 Query: 265 FDYDDEPEAVEESKK----EDTTAVTTTAPAAAVP------PAPTATVPAAAAPAAASPP 314 + + E KK +D+ ++T A +P P P +T P Sbjct: 1012 AEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSK 1071 Query: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQFQ--PRMMGIQQ-DPMHHQVPLPPNGQMPGFGLL 371 P P Q N+ F P + IQ+ ++ Q +GQ+ + Sbjct: 1072 DP------PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKM 1125 Query: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMS 429 P P P A P+ PT Q + + Q + + ++ + + E E+ +++VK +S Sbjct: 1126 PPAPSGPKASPMPVPTESSSQ--KTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181 Score = 34.7 bits (78), Expect = 0.52 Identities = 53/236 (22%), Positives = 78/236 (33%), Gaps = 25/236 (10%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPP-TQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQL 201 P + + S P K ++PP TP P P P + L Q Q Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSP 430 Query: 202 QQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKA--AFPPPEQKTAFDK 259 + + P + P A A +AQ +T PT+P Q A PPP+Q Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ-QTGPTKPPSQLPGPAKPPPQQ------ 483 Query: 260 KLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPA--AASPPPPQ 317 P + ++ +A + + P P PA +P ++ PP Q Sbjct: 484 -----------PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532 Query: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373 P G QQP+ + +P P+ P Q P GL T Sbjct: 533 QP-GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587 Score = 33.9 bits (76), Expect = 0.89 Identities = 43/206 (20%), Positives = 71/206 (34%), Gaps = 23/206 (11%) Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVP---PA 297 P +Q+ P P+Q+ D D P+++ + E + + P P P Sbjct: 210 PLQQQPPKPIPKQQGPGR----DPLQQDGTPKSISSQQPEK---IKSQPPGTGKPIQGPT 262 Query: 298 PTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQV 357 T A P PQ +Q + +++ +P + + P+ Sbjct: 263 QTPQTDHAKLPLQRDASRPQT---------KQADIVRGESV---KPSLPSPSKPPIQQPT 310 Query: 358 PLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVE 417 P P Q PG P P AQP P QQP Q P T KP Q + Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ-PPGTTKPPAQPLGPA 369 Query: 418 QPCIQEVKRHMSDNRKSRSRSASRSP 443 +P Q+ + + ++ ++ P Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPP 395 Score = 33.9 bits (76), Expect = 0.89 Identities = 16/39 (41%), Positives = 17/39 (43%), Gaps = 7/39 (17%) Query: 920 QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 QPP P P P P P PPP PPPT +P Sbjct: 2404 QPPPPPPPPPPPPPPPPP-------PPPPPLPPPTSPKP 2435 Score = 33.1 bits (74), Expect = 1.5 Identities = 56/285 (19%), Positives = 97/285 (34%), Gaps = 31/285 (10%) Query: 118 QKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAV 177 Q+ G K QP + + PV++ + PP + +PP+Q P ++ Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI--C 589 Query: 178 PQLPSSDAFAAV---AQLFQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQ---AIT 231 P +++ V A T+ Q L F P P + + Q A+ Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN--PNPHLTEVKEWLCLNCQMKRALG 647 Query: 232 AQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV--TTTA 289 L P+ P + K P +A K P+ + S K+D + A Sbjct: 648 GDLAPVPSSP-QPKLKTAPVTTTSAVSK---------SSPQPQQTSPKKDAAPKQDLSKA 697 Query: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 349 P PP +P+A + PP+A D + +PA + ++ Q + Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEA------DSLSKPAPPKEPSVPSEQDKAPVAD 751 Query: 350 QDPMHHQVPLPPNGQMPGFGLLPTPPFPP---MAQPVIPPTPPVQ 391 P ++ P + P P +Q TPP++ Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796 Score = 32.7 bits (73), Expect = 2.0 Identities = 35/179 (19%), Positives = 77/179 (43%), Gaps = 31/179 (17%) Query: 924 QPQQQPQPQAPQQPQQQQQQQP---------PPSQQPPPTQQQPQQFRNDNRQQFNSGRD 974 + + QP +P+QP+ Q++ Q + +++ F+ D++Q S +D Sbjct: 1433 EKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKD 1492 Query: 975 QERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSS-- 1032 + + F + + RE Y + + ++ N SP + +R RR+S Sbjct: 1493 HKE--KSEFVDDITTRREPYDSVEESSESEN---------SP-------VPQRKRRTSVG 1534 Query: 1033 GHRDRERDSRDRESRREKEEARGKEKPEVT--DRAGGNKTVEPPISQVGNVDTASELEK 1089 E D + E+E+ K+ E++ + A G++ E +Q+ + +++E +K Sbjct: 1535 SSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK 1593 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 91.3 bits (225), Expect = 5e-18 Identities = 91/314 (28%), Positives = 110/314 (35%), Gaps = 77/314 (24%) Query: 665 PVPPIPVPAPITVPPPQVPPHQPG----PPVVGALQPPAFTPPLGIPPPGFGPGVPPPPP 720 P P +P T+ P +PP P GA + P + PPP P PPP P Sbjct: 131 PSPRLPNK---TISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLP 187 Query: 721 PP-PFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDS 779 PP P P P+ PPG L G P + PPV PP PP Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP------------------- 228 Query: 780 VKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQR 839 PP PTPP P S+L + V +P L PL Sbjct: 229 --------PPP-----PTPPPLPPASVLSDKAV------------------KPQLAPLHL 257 Query: 840 PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGM 899 PP +PPP PL+PP P + P P A PP P PP P+ Sbjct: 258 PP-IPPP----LPLLPPCGYPGL---KAEPASPAQDAQEPP----APPPPLPPYASCSPR 305 Query: 900 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 959 L P P P + PP P + P QAP Q Q PP+ PP Q Sbjct: 306 ASL----PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPA---PPGSQPFL 358 Query: 960 QFRNDNRQQFNSGR 973 Q + R G+ Sbjct: 359 QKKRHGRPGAGGGK 372 Score = 87.4 bits (215), Expect = 7e-17 Identities = 94/338 (27%), Positives = 117/338 (34%), Gaps = 94/338 (27%) Query: 639 NEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPP--HQPGPPVVGALQ 696 N +G A T+ P P P P P PP P+P P+ P P PGP G L Sbjct: 154 NTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL- 212 Query: 697 PPAFTPPLGIPPPGFGPGVPPPPPPPP--------FLRPGFNPMHLPPGFLPPGPPPPIT 748 P PP+ PP P PP PPP P ++P P+HLPP +PP Sbjct: 213 -PVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP--IPP------- 262 Query: 749 PPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLG 808 P P PP P L + A+ PPA P LP P + Sbjct: 263 -----PLPLLPPCGYPGLKAEPASPAQDAQE--------PPAPPPPLP------PYASCS 303 Query: 809 TQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGP 868 + P P + PG+ P PP P P + P Sbjct: 304 PRASLPAPPL-------------PGVNSSSETP-------------PPLP-PKSPSFQAP 336 Query: 869 PPGPGGFAMPPPHGMKGPFPPHG-PFV--RPGGMPGLGGPGPGPGGPEDRDGRQQPPQQP 925 P G A+P P P PP PF+ + G PG GG P PP P Sbjct: 337 PQKAGAQALPAP-----PAPPGSQPFLQKKRHGRPGAGGGKLNP-----------PPAPP 380 Query: 926 QQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRN 963 + P + + QQ + PTQQ Q RN Sbjct: 381 ARSPTTELSSKSQQ--------ATAWTPTQQPGGQLRN 410 Score = 70.9 bits (172), Expect = 7e-12 Identities = 97/354 (27%), Positives = 115/354 (32%), Gaps = 71/354 (20%) Query: 657 PIPKPLPVPVPPIPVPAPITVPPPQVPP--------HQPGPPVVGAL------------- 695 P P PLP P PP+ P P PPP PP + P AL Sbjct: 6 PPPPPLPPPPPPLGAPPP---PPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKV 62 Query: 696 ------QPPAFTPPLGIPPPGFGP----GVPPPPPPPPFLRPGFNPMHLPPGFLP----- 740 P G G G G PP GF P+ P G Sbjct: 63 TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGF-PVLRPAGQRDVAGGK 121 Query: 741 ----PG--PPPPITPPVSIPPPHTPPISIPNL--VSGARGNAESGDSVKMYGSAVPPAAP 792 PG P P P +I P PP S P L S A G A + + PP P Sbjct: 122 TGQGPGSRAPSPRLPNKTISGPLIPPAS-PRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180 Query: 793 TNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPST-GLLGARPGLIPLQRPPGMPPPHLQRF 851 P PP+ P L + P++ P T G L +P PP PPP Sbjct: 181 P--PPPPLPPP---LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP----- 230 Query: 852 PLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGG 911 P PP P+PP + P + P H P PP P + P G PGL P Sbjct: 231 PPTPP-PLPPASVLSDKAVKP---QLAPLH--LPPIPPPLPLLPPCGYPGLKAEPASPAQ 284 Query: 912 PEDRDGRQQPPQQPQQQPQPQA-----PQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 PP P P+A P + PPP P+ Q P Q Sbjct: 285 DAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQ 338 Score = 46.2 bits (108), Expect = 2e-04 Identities = 73/306 (23%), Positives = 97/306 (31%), Gaps = 84/306 (27%) Query: 141 AAPVAENVTNNEGSP---PPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAA--VAQLFQT 195 A+P N + G+ PP V + PP P P P LPSS V+ Sbjct: 148 ASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPL 207 Query: 196 TQGQQLQQILQTF-------QQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAF 248 T+G L + PP P P L A + +A+ QL P Sbjct: 208 TKG-NLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP------I 260 Query: 249 PPPEQKTAFDKKLLDRFDYDD---EPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVP-- 303 PPP LL Y EP + + +E PPAP +P Sbjct: 261 PPP-------LPLLPPCGYPGLKAEPASPAQDAQE--------------PPAPPPPLPPY 299 Query: 304 AAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNG 363 A+ +P A+ P PP PG + + P+ Q P Sbjct: 300 ASCSPRASLPAPP-----LPG------VNSSSETPPPLPPKSPSFQAPP----------- 337 Query: 364 QMPGFGLLPTPPFPPMAQPVI-----------------PPTPPVQQPFQASFQAQNEPLT 406 Q G LP PP PP +QP + PP PP + P + Sbjct: 338 QKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATA 397 Query: 407 QKPHQQ 412 P QQ Sbjct: 398 WTPTQQ 403 Score = 41.2 bits (95), Expect = 0.006 Identities = 44/175 (25%), Positives = 55/175 (31%), Gaps = 26/175 (14%) Query: 214 PQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEA 273 P SP L N A A TA + P P+ PPP P Sbjct: 147 PASPRLGNTSEAHGAARTAPPR--PNVPAPPPPTPPPPPPPL---------------PPP 189 Query: 274 VEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYT 333 + S T V+ P P P AP PPPP P P PA Sbjct: 190 LPSSSPIKTPLVSPPGPLTK-GNLPVVAPPVPCAPPPPPPPPPPTPPPLP------PASV 242 Query: 334 QHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTP 388 +P++ + P+ +PL P PG P P +P PP P Sbjct: 243 LSDKA--VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP 295 Score = 40.0 bits (92), Expect = 0.012 Identities = 65/289 (22%), Positives = 84/289 (29%), Gaps = 55/289 (19%) Query: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP 214 PPPP+ PP A P S L +D A L QG +L+++ Q + Sbjct: 14 PPPPLGAPPPPPPSAPPVSTDT-SSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQ 72 Query: 215 QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFP---PPEQKTAFDKKLLDRFDYDDEP 271 + A T T PT FP P Q+ K P Sbjct: 73 IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKT------GQGP 126 Query: 272 EAVEESKKEDTTAV--------------TTTAPAAAVPPAPTATVPAAAAPAAASPPPPQ 317 + S + + T+ A AA P VPA P PPPP Sbjct: 127 GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPL 186 Query: 318 APFGFPGDG------MQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371 P P + P N+ P VP P Sbjct: 187 PP-PLPSSSPIKTPLVSPPGPLTKGNLPVVAP------------PVPCAP---------- 223 Query: 372 PTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPC 420 PP PP P PP PP + + Q PL P + + PC Sbjct: 224 --PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC 270 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 90.9 bits (224), Expect = 6e-18 Identities = 96/333 (28%), Positives = 115/333 (34%), Gaps = 63/333 (18%) Query: 654 PVSPIPKPLPVPVPPIPVPAPI-----TVPPPQVP-PHQPGPPVVGALQPPAFTPPLGIP 707 PV +P P P P P +PPP P P PG P QPP P +P Sbjct: 682 PVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLP 741 Query: 708 ----PPGFGPGVPPPPPPPPFLRPGFN---PMHLPPGFLPPGP------PPPITPPVSIP 754 P P P PP PP+L P P L P +P P PP PP+ + Sbjct: 742 QVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVV 801 Query: 755 PPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPT---PPVTQPVSLLGTQG 811 PP TP I L PPA P +LPT PPV P Sbjct: 802 PPITPLAGIDGL---------------------PPALP-DLPTATVPPVPPPQYF----- 834 Query: 812 VAPGPVIGLQAPSTGLLGARPGL----IPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 867 P + L + + L A P L + L PPG P R ++P P ++ Sbjct: 835 ---SPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCR-TIVPNAPATIPLLAVA 890 Query: 868 PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQ 927 PP G A H P G V P P + P + P QP Sbjct: 891 PP----GVAALSIHSAVAQLP--GQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPAL 944 Query: 928 QPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960 PQP P QP Q PP PP +P Q Sbjct: 945 PPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQ 977 Score = 83.6 bits (205), Expect = 1e-15 Identities = 99/342 (28%), Positives = 124/342 (36%), Gaps = 76/342 (22%) Query: 654 PVSPIPKPLPVPVPP--------IPVPAPITVPPPQVPPHQPGPP-------VVGALQPP 698 P +P+P P PP P P P + P V P QP PP + P Sbjct: 713 PSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP 772 Query: 699 AFTPPLGIPPPGFGP--GVPPPPPPPPFLRPGFNPM----HLPPGFLPPGPPPPITPPVS 752 A PL +P P VPP PP P + P P+ LPP P P PPV Sbjct: 773 AQLKPLQMPQAPLQPLAQVPPQMPPIPVV-PPITPLAGIDGLPPAL--PDLPTATVPPVP 829 Query: 753 IPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAP------TNLPTP---PVTQP 803 P +P + +P+L + +PPA+P LP P P+ P Sbjct: 830 PPQYFSPAVILPSL-----------------AAPLPPASPALPLQAVKLPHPPGAPLAMP 872 Query: 804 VSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHM 863 + A P++ + P L + L PG P + FP M P +PP Sbjct: 873 CRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL---PGQ-PVYPAAFPQMAPTDVPPSP 928 Query: 864 MH-----RGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGR 918 H R PP P A+PP P P P + P P L P P P Sbjct: 929 HHTVQNMRATPPQP---ALPPQ-----PTLPPQPVLPP--QPTL---PPQPVLPPQPTRP 975 Query: 919 QQP--PQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958 QP P QP PQP P PQ +P P Q P Q P Sbjct: 976 PQPVLPPQPMLPPQPVLP--PQPALPVRPEPLQPHLPEQAAP 1015 Score = 80.1 bits (196), Expect = 1e-14 Identities = 116/448 (25%), Positives = 161/448 (35%), Gaps = 103/448 (22%) Query: 653 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQ-PGPPVVGALQPPAFTPPLGIPPP-- 709 +PV P+ +P+P +PP PA P Q+ P Q P P+ Q P PP+ + PP Sbjct: 747 QPVVPL-QPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPIT 805 Query: 710 ------GFGPGVP-------PPPPPPPFLRPGFNPMHLPPGFLPPGPP-PPITPPVSIPP 755 G P +P PP PPP + F+P + P P PP P P ++ Sbjct: 806 PLAGIDGLPPALPDLPTATVPPVPPPQY----FSPAVILPSLAAPLPPASPALPLQAVKL 861 Query: 756 PHTP---------------PISIPNLVSGARGNAESG--------DSVKMYGSAVPPAAP 792 PH P P +IP L G A +Y +A P AP Sbjct: 862 PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAP 921 Query: 793 TNLPTPP--------VTQPVSLLGTQ-GVAPGPVIGLQ--APSTGLLGARPGLIP---LQ 838 T++P P T P L Q + P PV+ Q P +L +P P L Sbjct: 922 TDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981 Query: 839 RPPGMPP-PHLQRFPLMP--PRPMPPHMMHRGPP---PG-------PGGFA--------- 876 P +PP P L P +P P P+ PH+ + P PG P +A Sbjct: 982 PQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPT 1041 Query: 877 --MPPPHGMKGPFP----PHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQP----- 925 +PP + P P P P + P L + PP P Sbjct: 1042 VPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGG 1101 Query: 926 ----QQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRR 981 P Q +P Q++Q SQ PP PQ + SG++ Sbjct: 1102 PGIASPCPTVQLTVEPVQEEQ----ASQDKPP--GLPQSCESYGGSDVTSGKELSDSCEG 1155 Query: 982 SF-GNRVENDRERYGNRNDDRDNSNRDR 1008 +F G R+E R +R R S ++R Sbjct: 1156 AFGGGRLEGRAARKHHRRSTRARSRQER 1183 Score = 51.6 bits (122), Expect = 4e-06 Identities = 63/226 (27%), Positives = 82/226 (36%), Gaps = 31/226 (13%) Query: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVV 692 +P P + V QN A T P +P +P P+ P P P P +PP PP Sbjct: 924 VPPSPHHTV-QNMRA----TPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP-Q 977 Query: 693 GALQPPAFTPPLGIPPPGFGPGVPPPPPP-PPFLRPGFNPMHLPPGFLPPGPPPPI---- 747 L P PP + PP P +P P P P L P P + G P P Sbjct: 978 PVLPPQPMLPPQPVLPP--QPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDV 1035 Query: 748 ---TPPVSIPP-----PHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPP 799 P V +PP P P + +P S +V +VP T L PP Sbjct: 1036 AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLL--PP 1093 Query: 800 VTQPVSLLGTQGVA-PGPVIGLQAPSTGLLGARPGLIPLQRPPGMP 844 P L G G+A P P + L + +PPG+P Sbjct: 1094 ANPP--LPGGPGIASPCPTVQLTVEP-----VQEEQASQDKPPGLP 1132 Score = 48.9 bits (115), Expect = 3e-05 Identities = 66/264 (25%), Positives = 87/264 (32%), Gaps = 50/264 (18%) Query: 654 PVSPIPKP-LPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFG 712 PV+ P P P PP+P+ + +PP P + + + P+F + G Sbjct: 1317 PVAEHPAPEAPESSPPLPLSS---LPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQA-G 1372 Query: 713 PGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARG 772 P PP PP P L P PP P P T + P Sbjct: 1373 PSNPPGAPPAP---------------LAPSSPPVTALPQDGAAPATSTMPEP-------- 1409 Query: 773 NAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP 832 SG + + G P + L T +QP++ +A P++ AP T Sbjct: 1410 --ASGTASQAGGPGTPQGLTSELET---SQPLAETHEAPLAVQPLVVGLAPCT------- 1457 Query: 833 GLIPLQRPPGMPPPHLQRFPLMPPRPMP-PHMMHRGPPPGPGGFAMPPPHGMKG------ 885 P R PL PP P P PH P G +P G Sbjct: 1458 ---PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQL 1514 Query: 886 PFPPHGPFVRPGGMPGLGGPGPGP 909 P PP GP V P L G GP Sbjct: 1515 PSPPLGPTVPPQPPSALESDGEGP 1538 Score = 48.5 bits (114), Expect = 3e-05 Identities = 81/322 (25%), Positives = 108/322 (33%), Gaps = 35/322 (10%) Query: 165 PPTQATPNSVPAVPQLPSSDAF-AAVAQLFQT----TQGQQLQQILQTFQQPPKPQSPAL 219 PP A + AV QLP + AA Q+ T + +Q + T QP P P L Sbjct: 891 PPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTL 950 Query: 220 DNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKK 279 + Q P QP+ PP+ L + PE ++ Sbjct: 951 PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLP 1010 Query: 280 EDTTAVTTTAPAAAVP-PAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNM 338 E T + PAP A AA P P PP A P + PA + + Sbjct: 1011 EQAAPAATPGSQILLGHPAPYAVDVAAQVPTV--PVPPAAVLSPPLPEVLLPAAPEL--L 1066 Query: 339 DQFQPRMM----GIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPF 394 QF + +Q P LPP P P P +A P P +P Sbjct: 1067 PQFPSSLATVSASVQSVPTQTATLLPPANP-------PLPGGPGIASPC-PTVQLTVEPV 1118 Query: 395 QASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSGSRS 454 Q +Q++P + Q C SD + S S R R+ Sbjct: 1119 QEEQASQDKP---------PGLPQSC---ESYGGSDVTSGKELSDSCEGAFGGGRLEGRA 1166 Query: 455 RRSRHRRS-RSRSRDRRRHSPR 475 R HRRS R+RSR R PR Sbjct: 1167 ARKHHRRSTRARSRQERASRPR 1188 Score = 47.4 bits (111), Expect = 8e-05 Identities = 71/283 (25%), Positives = 99/283 (34%), Gaps = 45/283 (15%) Query: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202 PVAE+ PP+ +SS PP +A+ +S P QL S + + +A QQL Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPP-EASQDSAPYKDQLSSKEQPSFLAS-------QQLL 1368 Query: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262 P P +P ++ T T P P TA Sbjct: 1369 SQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPE--------PASGTA------ 1414 Query: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAAS---------P 313 + P+ + + T AV P P AP AAS P Sbjct: 1415 SQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREP 1474 Query: 314 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373 PP AP P G QPA Q + P +G Q+P PP G PT Sbjct: 1475 LPPPAPEPSPHSGTPQPALGQPAPL---LPAAVG-AVSLATSQLPSPPLG--------PT 1522 Query: 374 -PPFPPMAQPVIPPTPPVQQPF-QASFQAQNEPLTQKPHQQEM 414 PP PP A PP + F ++ ++ +E L +Q+ + Sbjct: 1523 VPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565 Score = 43.9 bits (102), Expect = 9e-04 Identities = 70/283 (24%), Positives = 87/283 (30%), Gaps = 54/283 (19%) Query: 133 DMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQL 192 D A G V G P PP E P P LP+S A Sbjct: 562 DKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP------PTLPTSATSLASDST 615 Query: 193 FQTTQGQQLQQILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPE 252 F + QG + Q+ QQ +VM A A PS + PP Sbjct: 616 FDSGQGSTVYSDSQSSQQ-----------SVMLGSLADAA--------PSPAQCVCSPPV 656 Query: 253 QKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAAS 312 + + L +P A + PA A PP+ P A A Sbjct: 657 SEGPVLPQSLPSLGAYQQPTAAPGLP-------VGSVPAPACPPSLQQHFPDPAMSFAPV 709 Query: 313 PPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 372 PPP P G G QP G Q P+ PLP + ++P Sbjct: 710 LPPPSTPMP-TGPG---------------QPAPPGQQPPPLAQPTPLPQ--VLAPQPVVP 751 Query: 373 TPPFPPMAQPVIPPTPPVQQPFQAS----FQAQNEPLTQKPHQ 411 P PP P + P V P Q QA +PL Q P Q Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794 Score = 43.5 bits (101), Expect = 0.001 Identities = 62/245 (25%), Positives = 84/245 (34%), Gaps = 38/245 (15%) Query: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQL-KTTPTQPSEQKAAFPPPEQKTAFDKKLLDR 264 Q P K + P + V A Q P +P + PP +A Sbjct: 556 QDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDST 615 Query: 265 FD-------YDDEPEAVEESKKEDTTAVTTTAPAAAV--PPAPTATVPAAAAPAAASPPP 315 FD Y D ++ ++S + A +PA V PP V + P+ + Sbjct: 616 FDSGQGSTVYSDS-QSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQ 674 Query: 316 PQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPT 373 P A G P + PA ++ Q P DP P+ PP+ MP P Sbjct: 675 PTAAPGLPVGSVPAPACPP--SLQQHFP-------DPAMSFAPVLPPPSTPMPTGPGQPA 725 Query: 374 PPF---PPMAQP-----------VIP--PTPPVQQPFQASFQAQNEPLTQKPHQQEMEVE 417 PP PP+AQP V+P P PP P+ A P KP Q Sbjct: 726 PPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPL 785 Query: 418 QPCIQ 422 QP Q Sbjct: 786 QPLAQ 790 Score = 40.4 bits (93), Expect = 0.010 Identities = 33/105 (31%), Positives = 37/105 (35%), Gaps = 24/105 (22%) Query: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVG 693 P P E A A P P+P P P P P P P P + P G + Sbjct: 1455 PCTPAPEAASTRDASA----PREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLA 1510 Query: 694 ALQPPAFTPPLGIPPPGFGPGVPPPPP---------PPPFLRPGF 729 Q +P P GP VPP PP PPP R GF Sbjct: 1511 TSQ---------LPSPPLGPTVPPQPPSALESDGEGPPP--RVGF 1544 Score = 37.7 bits (86), Expect = 0.062 Identities = 62/273 (22%), Positives = 79/273 (28%), Gaps = 67/273 (24%) Query: 125 IEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSD 184 I ++ P+ +A G P ++ P PP + S P P+ +P P+S Sbjct: 798 IPVVPPITPLA-GIDGLPPALPDLPTATVPPVPPPQYFS--PAVILPSLAAPLP--PASP 852 Query: 185 AFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDNA----VMAQVQAITAQLKTTPTQ 240 A A G L +T P L A + + AQL P Sbjct: 853 ALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVY 912 Query: 241 PSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTA 300 P AAFP P V S + T P A+PP PT Sbjct: 913 P----AAFPQMA------------------PTDVPPSPHHTVQNMRATPPQPALPPQPTL 950 Query: 301 TVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLP 360 P PP P P Q Q LP Sbjct: 951 PPQPVLPPQPTLPPQPVLP-----------------------------PQPTRPPQPVLP 981 Query: 361 PNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP 393 P +P P P PP QP +P P QP Sbjct: 982 PQPMLP-----PQPVLPP--QPALPVRPEPLQP 1007 Score = 35.8 bits (81), Expect = 0.23 Identities = 37/144 (25%), Positives = 48/144 (33%), Gaps = 26/144 (18%) Query: 621 LDSDTLNPDWKGIPKKPENEVAQNGGAET-----SHTEPVSPIPKP--LPVPVPPIPVPA 673 L D P +P+ +Q GG T S E P+ + P+ V P+ V Sbjct: 1394 LPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGL 1453 Query: 674 PITVPPPQVP-------PHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLR 726 P P+ P +P PP P +P G P P G P P L Sbjct: 1454 APCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPALGQ-------PAPLLP 1501 Query: 727 PGFNPMHLPPGFLPPGPPPPITPP 750 + L LP P P PP Sbjct: 1502 AAVGAVSLATSQLPSPPLGPTVPP 1525 Score = 32.0 bits (71), Expect = 3.4 Identities = 28/127 (22%), Positives = 47/127 (37%), Gaps = 19/127 (14%) Query: 832 PGLIPLQRPPGMPPPHLQRFPLM---------------PPRPMPPHMMHRGPPPGPGGFA 876 PGL + P PP LQR L+ P P P ++ + PG A Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADA 114 Query: 877 MPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQ 936 P P G + P GP + P GP R++ + +P+P ++ Sbjct: 115 GPEPVGTQEP----GPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRR 170 Query: 937 PQQQQQQ 943 + ++++ Sbjct: 171 DEPEEEE 177 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,253,963 Number of Sequences: 37866 Number of extensions: 5548137 Number of successful extensions: 135710 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1338 Number of HSP's successfully gapped in prelim test: 2266 Number of HSP's that attempted gapping in prelim test: 29605 Number of HSP's gapped (non-prelim): 46882 length of query: 1125 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1012 effective length of database: 13,968,660 effective search space: 14136283920 effective search space used: 14136283920 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.