Search of human proteins with 223941882

Search of human proteins with 223941882

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223941882 protein tyrosine phosphatase, non-receptor type 3
isoform 3 [Homo sapiens]
         (782 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i...  1602   0.0  
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i...  1602   0.0  
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i...  1485   0.0  
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i...  1485   0.0  
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i...  1283   0.0  
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i...  1166   0.0  
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho...   783   0.0  
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [...   214   2e-55
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ...   194   2e-49
gi|4506291 protein tyrosine phosphatase, non-receptor type 2 iso...   191   3e-48
gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [H...   191   3e-48
gi|18104980 protein tyrosine phosphatase, non-receptor type 2 is...   191   3e-48
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...   190   5e-48
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...   190   5e-48
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...   190   5e-48
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...   190   5e-48
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A...   185   1e-46
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A...   185   1e-46
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A...   185   1e-46
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ...   185   1e-46
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ...   185   1e-46
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ...   185   1e-46
gi|148728162 protein tyrosine phosphatase, receptor type, J isof...   182   1e-45
gi|4506289 protein tyrosine phosphatase, non-receptor type 1 [Ho...   180   4e-45
gi|241896926 protein tyrosine phosphatase, receptor type, H isof...   179   7e-45
gi|241896924 protein tyrosine phosphatase, receptor type, H isof...   179   7e-45
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   177   4e-44
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   177   4e-44
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...   173   5e-43
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   173   5e-43

>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
           isoform 3 [Homo sapiens]
          Length = 782

 Score = 1602 bits (4147), Expect = 0.0
 Identities = 782/782 (100%), Positives = 782/782 (100%)

Query: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60
           MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL
Sbjct: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60

Query: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120
           HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS
Sbjct: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120

Query: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
           FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK
Sbjct: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180

Query: 181 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 240
           KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR
Sbjct: 181 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 240

Query: 241 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 300
           SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ
Sbjct: 241 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 300

Query: 301 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 360
           NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE
Sbjct: 301 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 360

Query: 361 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 420
           DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP
Sbjct: 361 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 420

Query: 421 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 480
           KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL
Sbjct: 421 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 480

Query: 481 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 540
           NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL
Sbjct: 481 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 540

Query: 541 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 600
           DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV
Sbjct: 541 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 600

Query: 601 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 660
           VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT
Sbjct: 601 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 660

Query: 661 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 720
           NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV
Sbjct: 661 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 720

Query: 721 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 780
           LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD
Sbjct: 721 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 780

Query: 781 PS 782
           PS
Sbjct: 781 PS 782


>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
           isoform 1 [Homo sapiens]
          Length = 913

 Score = 1602 bits (4147), Expect = 0.0
 Identities = 782/782 (100%), Positives = 782/782 (100%)

Query: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60
           MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL
Sbjct: 132 MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 191

Query: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120
           HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS
Sbjct: 192 HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 251

Query: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
           FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK
Sbjct: 252 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 311

Query: 181 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 240
           KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR
Sbjct: 312 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 371

Query: 241 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 300
           SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ
Sbjct: 372 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 431

Query: 301 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 360
           NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE
Sbjct: 432 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 491

Query: 361 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 420
           DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP
Sbjct: 492 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 551

Query: 421 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 480
           KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL
Sbjct: 552 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 611

Query: 481 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 540
           NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL
Sbjct: 612 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 671

Query: 541 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 600
           DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV
Sbjct: 672 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 731

Query: 601 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 660
           VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT
Sbjct: 732 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 791

Query: 661 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 720
           NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV
Sbjct: 792 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 851

Query: 721 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 780
           LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD
Sbjct: 852 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 911

Query: 781 PS 782
           PS
Sbjct: 912 PS 913


>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
           isoform 4 [Homo sapiens]
          Length = 737

 Score = 1485 bits (3845), Expect = 0.0
 Identities = 737/782 (94%), Positives = 737/782 (94%), Gaps = 45/782 (5%)

Query: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60
           MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL
Sbjct: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60

Query: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120
           HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS
Sbjct: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120

Query: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
           FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK
Sbjct: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180

Query: 181 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 240
           KLLPQEKNVLSQYWTMGSRNTKK                                     
Sbjct: 181 KLLPQEKNVLSQYWTMGSRNTKK------------------------------------- 203

Query: 241 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 300
                   RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ
Sbjct: 204 --------RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 255

Query: 301 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 360
           NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE
Sbjct: 256 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 315

Query: 361 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 420
           DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP
Sbjct: 316 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 375

Query: 421 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 480
           KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL
Sbjct: 376 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 435

Query: 481 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 540
           NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL
Sbjct: 436 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 495

Query: 541 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 600
           DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV
Sbjct: 496 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 555

Query: 601 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 660
           VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT
Sbjct: 556 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 615

Query: 661 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 720
           NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV
Sbjct: 616 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 675

Query: 721 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 780
           LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD
Sbjct: 676 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 735

Query: 781 PS 782
           PS
Sbjct: 736 PS 737


>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
           isoform 2 [Homo sapiens]
          Length = 868

 Score = 1485 bits (3845), Expect = 0.0
 Identities = 737/782 (94%), Positives = 737/782 (94%), Gaps = 45/782 (5%)

Query: 1   MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 60
           MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL
Sbjct: 132 MDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESL 191

Query: 61  HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 120
           HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS
Sbjct: 192 HEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTS 251

Query: 121 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
           FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK
Sbjct: 252 FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 311

Query: 181 KLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSR 240
           KLLPQEKNVLSQYWTMGSRNTKK                                     
Sbjct: 312 KLLPQEKNVLSQYWTMGSRNTKK------------------------------------- 334

Query: 241 SPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 300
                   RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ
Sbjct: 335 --------RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQ 386

Query: 301 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 360
           NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE
Sbjct: 387 NRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTE 446

Query: 361 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 420
           DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP
Sbjct: 447 DASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIP 506

Query: 421 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 480
           KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL
Sbjct: 507 KLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDEL 566

Query: 481 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 540
           NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL
Sbjct: 567 NQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNL 626

Query: 541 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 600
           DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV
Sbjct: 627 DKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQV 686

Query: 601 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 660
           VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT
Sbjct: 687 VWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVT 746

Query: 661 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 720
           NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV
Sbjct: 747 NTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGV 806

Query: 721 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 780
           LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD
Sbjct: 807 LVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLD 866

Query: 781 PS 782
           PS
Sbjct: 867 PS 868


>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
           isoform 5 [Homo sapiens]
          Length = 626

 Score = 1283 bits (3319), Expect = 0.0
 Identities = 626/626 (100%), Positives = 626/626 (100%)

Query: 157 MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGG 216
           MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGG
Sbjct: 1   MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGG 60

Query: 217 MVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYIT 276
           MVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYIT
Sbjct: 61  MVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYIT 120

Query: 277 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS 336
           ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS
Sbjct: 121 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS 180

Query: 337 CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG 396
           CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG
Sbjct: 181 CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG 240

Query: 397 GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS 456
           GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS
Sbjct: 241 GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS 300

Query: 457 RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL 516
           RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL
Sbjct: 301 RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL 360

Query: 517 IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA 576
           IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA
Sbjct: 361 IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA 420

Query: 577 ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH 636
           ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH
Sbjct: 421 ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH 480

Query: 637 GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY 696
           GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY
Sbjct: 481 GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY 540

Query: 697 VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT 756
           VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT
Sbjct: 541 VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT 600

Query: 757 SSQYKFVCEAILRVYEEGLVQMLDPS 782
           SSQYKFVCEAILRVYEEGLVQMLDPS
Sbjct: 601 SSQYKFVCEAILRVYEEGLVQMLDPS 626


>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
           isoform 6 [Homo sapiens]
          Length = 581

 Score = 1166 bits (3017), Expect = 0.0
 Identities = 581/626 (92%), Positives = 581/626 (92%), Gaps = 45/626 (7%)

Query: 157 MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGG 216
           MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKK             
Sbjct: 1   MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKK------------- 47

Query: 217 MVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYIT 276
                                           RSPRLRHEIRKPRHSSADNLANEMTYIT
Sbjct: 48  --------------------------------RSPRLRHEIRKPRHSSADNLANEMTYIT 75

Query: 277 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS 336
           ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS
Sbjct: 76  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGS 135

Query: 337 CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG 396
           CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG
Sbjct: 136 CSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKG 195

Query: 397 GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS 456
           GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS
Sbjct: 196 GVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHS 255

Query: 457 RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL 516
           RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL
Sbjct: 256 RELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVL 315

Query: 517 IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA 576
           IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA
Sbjct: 316 IQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPA 375

Query: 577 ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH 636
           ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH
Sbjct: 376 ANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNH 435

Query: 637 GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY 696
           GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY
Sbjct: 436 GGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNY 495

Query: 697 VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT 756
           VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT
Sbjct: 496 VRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQT 555

Query: 757 SSQYKFVCEAILRVYEEGLVQMLDPS 782
           SSQYKFVCEAILRVYEEGLVQMLDPS
Sbjct: 556 SSQYKFVCEAILRVYEEGLVQMLDPS 581


>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
           sapiens]
          Length = 926

 Score =  783 bits (2022), Expect = 0.0
 Identities = 414/820 (50%), Positives = 541/820 (65%), Gaps = 68/820 (8%)

Query: 2   DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLH 61
           DI  GRL CP N+A +LAS+AVQS  GDY+ S +  GYLSD  FIP+Q +DF  ++  LH
Sbjct: 133 DILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLH 192

Query: 62  EQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSF 121
           +QH GL  +EAE  Y+N ARTL+ YGVE H  RD  N ++MIG+ S G+ +Y+  +  + 
Sbjct: 193 QQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNT 252

Query: 122 YPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 181
           +PW+ I+KISFK K+FFI  R++  ESRE ++ FNM+NYR+CKNLWK+CVEHHTFF+  +
Sbjct: 253 FPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDR 312

Query: 182 LLPQEKNVLSQYWTMGS------RNTKKSVNNQYCKKVIGG----------------MVW 219
            LP +KN  + Y+T+GS      R   +SV  QY K+                    M W
Sbjct: 313 PLPPQKNFFAHYFTLGSKFRYCGRTEVQSV--QYGKEKANKDRVFARSPSKPLARKLMDW 370

Query: 220 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETE 279
               R S+S + LET+SLPSRSPP TPN R+     E  + R SS  +L + M +     
Sbjct: 371 EVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMVHT---- 426

Query: 280 DVFYTYKGSLAPQDSDSEVSQN-RSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCS 338
                         S SEV  N RSP       +  A S + + S S  +P    P +  
Sbjct: 427 --------------SPSEVFVNQRSP------SSTQANSIVLESSPSQETPGDGKPPALP 466

Query: 339 PDGVDQQLLDDFHRVTKGGSTEDASQYYCDKND----------NGD---SYLVLIRITPD 385
           P    Q   + ++++    S +D   +  +  D          NG      LVLIR+ PD
Sbjct: 467 PK---QSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIPHDNLVLIRMKPD 523

Query: 386 EDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVV 445
           E+G+FGFN+KGG DQKMP++VSR+ P +PAD C+P+LNEGDQ+VLINGRDI+EHTHDQVV
Sbjct: 524 ENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVV 583

Query: 446 MFIKASRESHSRELALVIRRRAVRSFADFKSEDELN-QLFPE-AIFPMCPEGGDTLEGSM 503
           +FIKAS E HS EL L++R  AV    + K E+E + Q  PE A      +   +L  SM
Sbjct: 584 LFIKASCERHSGELMLLVRPNAVYDVVEEKLENEPDFQYIPEKAPLDSVHQDDHSLRESM 643

Query: 504 AQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNED 563
            QL +GL +GTVL QF+QLYRKKPG+ ++ AKLPQN+ KNRY+D+ PYD TRV+L+GNED
Sbjct: 644 IQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNED 703

Query: 564 YINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKC 623
           YINA+Y+NMEIP+++++N+YIA QGPLPHTC  FWQ+ W+Q  S++VMLTT  ERGR KC
Sbjct: 704 YINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKC 763

Query: 624 HQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGV 683
           HQYWP+P    ++G + + C SE+   AY+ R+M + N +  E   +T +QY+AWPDHGV
Sbjct: 764 HQYWPEPTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGV 823

Query: 684 PDDSSDFLEFVNYVRSLRV-DSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDI 742
           PDDSSDFL+FV +VR+ R    EPV+VHCSAGIGRTGVL+TMETAMCL E N P+YPLDI
Sbjct: 824 PDDSSDFLDFVCHVRNKRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDI 883

Query: 743 VRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS 782
           VR MRDQRAMM+QT SQY+FVCEAIL+VYEEG V+ L  S
Sbjct: 884 VRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTS 923


>gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [Homo
            sapiens]
          Length = 1187

 Score =  214 bits (546), Expect = 2e-55
 Identities = 110/282 (39%), Positives = 168/282 (59%), Gaps = 20/282 (7%)

Query: 506  LKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLL----QGN 561
            LKK LE G V  ++EQ+ +KK     + A LP+N +++R ++V+PY+  RV L    + N
Sbjct: 900  LKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENN 959

Query: 562  EDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRT 621
              YINAS++ + +  A     YIATQGPLPHTC  FWQ+VW+Q +++I M+T   E GRT
Sbjct: 960  TGYINASHIKVVVGGAEW--HYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRT 1017

Query: 622  KCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAW 678
            K H+YWP          +G F +  +    ++ Y +  + V +  +G+E TV HLQY  W
Sbjct: 1018 KSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDW 1077

Query: 679  PDHGVPDDSSDFLEFVNYVRSLRVDSE-----------PVLVHCSAGIGRTGVLVTMETA 727
            PDHG P+D   FL ++  ++S+R  +            P++VHCSAG+GRTGVL+  E  
Sbjct: 1078 PDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELM 1137

Query: 728  MCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILR 769
            +   E N  +    ++R +R+QR  M+QT +QYKFV + +++
Sbjct: 1138 IYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQ 1179



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 52/195 (26%), Positives = 88/195 (45%), Gaps = 14/195 (7%)

Query: 2   DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQN-------EDFL 54
           D+ EGRL C L+  + LA  AVQ+ FGDYN       +L +    P          E+  
Sbjct: 125 DVLEGRLRCTLDQVIRLAGLAVQADFGDYNQ-FDSQDFLREYVLFPMDLALEEAVLEELT 183

Query: 55  TKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYR 114
            KV   H+ HSG+  +EAE  YIN    LD +G E+   +D H   + +GI   G+ V  
Sbjct: 184 QKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRN 243

Query: 115 KYICTS-FYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEH 173
           +    +  Y W ++  I+  +    +     +  ++E    F+  +  + K + +     
Sbjct: 244 RIGRQAVIYRWNDMGNITHNKSTILV-----ELINKEETALFHTDDIENAKYISRLFATR 298

Query: 174 HTFFQAKKLLPQEKN 188
           H F++  K+  ++ N
Sbjct: 299 HKFYKQNKICTEQSN 313


>gi|150418005 protein tyrosine phosphatase, non-receptor type 21 [Homo
            sapiens]
          Length = 1174

 Score =  194 bits (494), Expect = 2e-49
 Identities = 106/283 (37%), Positives = 166/283 (58%), Gaps = 22/283 (7%)

Query: 506  LKKGLESGTVLIQFEQLYRKK--PGLAITFAKLPQNLDKNRYKDVLPYDTTRVLL----Q 559
            L++ LE G V  ++E++ +K+   G   T A+LP+N ++NR++DVLPYD  RV L    +
Sbjct: 887  LEQRLEQGMVFTEYERILKKRLVDGECST-ARLPENAERNRFQDVLPYDDVRVELVPTKE 945

Query: 560  GNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERG 619
             N  YINAS++ + +  + +   YIATQGPL +TC  FWQ+VW+Q +++I M+T   E G
Sbjct: 946  NNTGYINASHIKVSV--SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGG 1003

Query: 620  RTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYV 676
            R K  +YWP      + + +G F I  +    +  Y +  + + +  TG+E TV HLQY 
Sbjct: 1004 REKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYT 1063

Query: 677  AWPDHGVPDDSSDFLEFVNYVRSLR----------VDSEPVLVHCSAGIGRTGVLVTMET 726
             WP+HG P+D   FL ++  ++S+R            + P+LVHCSAG+GRTGV++  E 
Sbjct: 1064 DWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEI 1123

Query: 727  AMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILR 769
             +   E N  +    ++  +R QR M+VQT  QY FV   +++
Sbjct: 1124 MIACLEHNEVLDIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQ 1166



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 89/352 (25%), Positives = 140/352 (39%), Gaps = 61/352 (17%)

Query: 2   DICEGRLTCPLNSAVVLASYAVQSHFGDYNS----------SIHHPGYLSDSHFIPDQNE 51
           DI EG + C L  A+ LA  AVQ+ FGD++           ++   G+L D   +    E
Sbjct: 127 DILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKVL----E 182

Query: 52  DFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVA 111
           +   KV  LH+++ GL   +AE  Y+     +D YG E +  +D    D+ IG    G+ 
Sbjct: 183 EATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEGIF 242

Query: 112 V-YRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSC 170
           V ++       + W +I  +S  +  F +     +  ++E  + F   +  + K +W+ C
Sbjct: 243 VKHKNGRHPVVFRWHDIANMSHNKSFFAL-----ELANKEETIQFQTEDMETAKYIWRLC 297

Query: 171 VEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVE 230
           V  H F++  +      N+ +Q  T+                       NP  RRS S  
Sbjct: 298 VARHKFYRLNQC-----NLQTQTVTV-----------------------NPIRRRSSS-- 327

Query: 231 HLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNL--ANEMTYITETEDVFYTYKGS 288
                SLP   P + P            +P  SS DNL   N+  Y   ++      +  
Sbjct: 328 ---RMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQDNLFVPNQNGYYCHSQTSLDRAQID 384

Query: 289 LAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPD 340
           L  +  +  V    S +    S NNP Q YL Q S  S +PS        PD
Sbjct: 385 LNGRIRNGSVYSAHSTN----SLNNP-QPYL-QPSPMSSNPSITGSDVMRPD 430


>gi|4506291 protein tyrosine phosphatase, non-receptor type 2
           isoform 1 [Homo sapiens]
          Length = 415

 Score =  191 bits (484), Expect = 3e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 592
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92

Query: 593 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 650
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152

Query: 651 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 707
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212

Query: 708 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272

Query: 768 L 768
           +
Sbjct: 273 I 273


>gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [Homo
           sapiens]
          Length = 353

 Score =  191 bits (484), Expect = 3e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 592
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92

Query: 593 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 650
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152

Query: 651 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 707
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212

Query: 708 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272

Query: 768 L 768
           +
Sbjct: 273 I 273


>gi|18104980 protein tyrosine phosphatase, non-receptor type 2
           isoform 2 [Homo sapiens]
          Length = 387

 Score =  191 bits (484), Expect = 3e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 592
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92

Query: 593 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 650
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152

Query: 651 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 707
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212

Query: 708 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272

Query: 768 L 768
           +
Sbjct: 273 I 273


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score =  190 bits (482), Expect = 5e-48
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 474  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 2177 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2236

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 2237 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2294

Query: 594  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 2295 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2354

Query: 652  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 2355 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2413

Query: 712  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 2414 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2472



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 103/501 (20%), Positives = 197/501 (39%), Gaps = 66/501 (13%)

Query: 2    DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
            DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 686  DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745

Query: 56   KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
            ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 746  ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805

Query: 114  RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
              +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 806  EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860

Query: 170  CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226
            C   H F    +A++     +++         R + +S+N Q  + V G  +       S
Sbjct: 861  CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911

Query: 227  LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285
            L+   L   ++   S       R       + +P  +S+    ++ ++  +  ++  +Y 
Sbjct: 912  LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971

Query: 286  ---KGSLAPQDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSS 331
               + SL P   +  V+    P           HQ S S+           +S SV+  +
Sbjct: 972  DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLN 1031

Query: 332  NAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYL 377
             +P     +     + D        +T   S   +SQ    +ND          + +  +
Sbjct: 1032 RSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREI 1091

Query: 378  VLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLIN 432
             L+ +  D     GF + GG       + + +S + P  PAD   C   L  GD+++ +N
Sbjct: 1092 TLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVN 1148

Query: 433  GRDISEHTHDQVVMFIKASRE 453
               +   +H   +  ++ + E
Sbjct: 1149 SVSLEGVSHHAAIEILQNAPE 1169



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 220  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 1611 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1670

Query: 277  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 1671 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1730

Query: 326  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 1731 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1790

Query: 379  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 1791 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1847

Query: 437  SEHTHDQVVMFIKASRESHSRELALVIRR 465
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 1848 TNMTHTDAVNLLRAA----SKTVRLVIGR 1872


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score =  190 bits (482), Expect = 5e-48
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 474  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 1981 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2040

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 2041 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2098

Query: 594  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 2099 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2158

Query: 652  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 2159 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2217

Query: 712  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 2218 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2276



 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 61/240 (25%), Positives = 104/240 (43%), Gaps = 30/240 (12%)

Query: 2   DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
           DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 686 DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745

Query: 56  KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
           ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 746 ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805

Query: 114 RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
             +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 806 EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860

Query: 170 CVEHHTF-----FQAKKLLPQEKNVLSQYWTMGSR--------NTKKSVNNQYCKKVIGG 216
           C   H F      +      Q+ +VL + W++ S         N KK        ++IGG
Sbjct: 861 CSYQHKFQLQMRARQSNQDAQDIDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGG 920



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 220  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 1415 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1474

Query: 277  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 1475 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1534

Query: 326  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 1535 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1594

Query: 379  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 1595 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1651

Query: 437  SEHTHDQVVMFIKASRESHSRELALVIRR 465
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 1652 TNMTHTDAVNLLRAA----SKTVRLVIGR 1676



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 387  DGKFGFNLKGGVDQKMP---LVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQ 443
            D   G ++ GGV+  +    + V  + P+  A++   ++++GD+++ +NG  +   TH Q
Sbjct: 1184 DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESD-GRIHKGDRVLAVNGVSLEGATHKQ 1242

Query: 444  VV 445
             V
Sbjct: 1243 AV 1244


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score =  190 bits (482), Expect = 5e-48
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 474  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 2172 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2231

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 2232 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2289

Query: 594  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 2290 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2349

Query: 652  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 2350 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2408

Query: 712  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 2409 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2467



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 103/501 (20%), Positives = 197/501 (39%), Gaps = 66/501 (13%)

Query: 2    DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
            DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 686  DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745

Query: 56   KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
            ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 746  ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805

Query: 114  RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
              +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 806  EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860

Query: 170  CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226
            C   H F    +A++     +++         R + +S+N Q  + V G  +       S
Sbjct: 861  CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911

Query: 227  LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285
            L+   L   ++   S       R       + +P  +S+    ++ ++  +  ++  +Y 
Sbjct: 912  LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971

Query: 286  ---KGSLAPQDSDSEVSQNRSP-----------HQESLSENNPAQSYLTQKSSSSVSPSS 331
               + SL P   +  V+    P           HQ S S+           +S SV+  +
Sbjct: 972  DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLN 1031

Query: 332  NAPGSCSPDGVDQQLLDDFHR----VTKGGSTEDASQYYCDKND----------NGDSYL 377
             +P     +     + D        +T   S   +SQ    +ND          + +  +
Sbjct: 1032 RSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREI 1091

Query: 378  VLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLIN 432
             L+ +  D     GF + GG       + + +S + P  PAD   C   L  GD+++ +N
Sbjct: 1092 TLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVN 1148

Query: 433  GRDISEHTHDQVVMFIKASRE 453
               +   +H   +  ++ + E
Sbjct: 1149 SVSLEGVSHHAAIEILQNAPE 1169



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 220  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 1606 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1665

Query: 277  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 1666 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1725

Query: 326  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 1726 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1785

Query: 379  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 1786 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1842

Query: 437  SEHTHDQVVMFIKASRESHSRELALVIRR 465
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 1843 TNMTHTDAVNLLRAA----SKTVRLVIGR 1867



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 387  DGKFGFNLKGGVDQKMP---LVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQ 443
            D   G ++ GGV+  +    + V  + P+  A++   ++++GD+++ +NG  +   TH Q
Sbjct: 1375 DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESD-GRIHKGDRVLAVNGVSLEGATHKQ 1433

Query: 444  VV 445
             V
Sbjct: 1434 AV 1435


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score =  190 bits (482), Expect = 5e-48
 Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)

Query: 474  FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
            F + DEL  L    + P     G  L+  +  L+  L+ G    + E L   KP      
Sbjct: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
             +  +N  KNRYK++LPYD TRV L     YINAS++ + +     V  YIA QGPLP T
Sbjct: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270

Query: 594  CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
               FWQ++W+QK ++I M+T   E  + KC +YWP+      M      +          
Sbjct: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330

Query: 652  YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
            +V R M + + QT E   ++HL + AWPDH  P    D L F++Y+R +   S P++ HC
Sbjct: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389

Query: 712  SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
            SAGIGR+G L+ ++  + L  ++L     D+VR MR QR  MVQT  QY F  + IL V
Sbjct: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 98/484 (20%), Positives = 195/484 (40%), Gaps = 51/484 (10%)

Query: 2    DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
            DI E R+ C   ++++LAS A+Q+ +GDY   +H   Y    H++P +  + L       
Sbjct: 686  DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745

Query: 56   KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
            ++  LH  + G  + E E  ++ + + L  YGV  H           +++G+ S GV V+
Sbjct: 746  ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805

Query: 114  RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
              +         +PW    KISF +KK  +   Q  ++  +H   F   N + C+ L   
Sbjct: 806  EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860

Query: 170  CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226
            C   H F    +A++     +++         R + +S+N Q  + V G  +       S
Sbjct: 861  CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911

Query: 227  LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285
            L+   L   ++   S       R       + +P  +S+    ++ ++  +  ++  +Y 
Sbjct: 912  LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971

Query: 286  ---KGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGV 342
               + SL P   +  V+    P   +     P+   +++  + S++  +    S S   +
Sbjct: 972  DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQ-MSRSDAESLAGVTKLNNSKSVASL 1030

Query: 343  DQQLLDDFHRVTKGGSTEDASQYYC--------DKNDNGDSYLVLIRITPDEDGKFGFNL 394
            ++      H  +   S ED  Q Y             + +  + L+ +  D     GF +
Sbjct: 1031 NRSPERRKHE-SDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQI 1089

Query: 395  KGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 449
             GG       + + +S + P  PAD   C   L  GD+++ +N   +   +H   +  ++
Sbjct: 1090 IGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQ 1146

Query: 450  ASRE 453
             + E
Sbjct: 1147 NAPE 1150



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)

Query: 220  NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
            +PA     S +     S   +S     N  S + + + + P  R S +D+  + E   +T
Sbjct: 1587 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1646

Query: 277  ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
               ++  +   S   Q   + VSQ +S H+   S+ +      Y  QK         S+ 
Sbjct: 1647 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1706

Query: 326  SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
            S  P   APG       +      +D +H   +++    E+ +    D  ++ + + +  
Sbjct: 1707 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1766

Query: 379  --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
              LI +   E G  GF +  G  +    V   I   + +D    +L  GD+++ +N  D+
Sbjct: 1767 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1823

Query: 437  SEHTHDQVVMFIKASRESHSRELALVIRR 465
            +  TH   V  ++A+    S+ + LVI R
Sbjct: 1824 TNMTHTDAVNLLRAA----SKTVRLVIGR 1848



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 387  DGKFGFNLKGGVDQKMP---LVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQ 443
            D   G ++ GGV+  +    + V  + P+  A++   ++++GD+++ +NG  +   TH Q
Sbjct: 1356 DNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESD-GRIHKGDRVLAVNGVSLEGATHKQ 1414

Query: 444  VV 445
             V
Sbjct: 1415 AV 1416


>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
           isoform 8 [Homo sapiens]
          Length = 339

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 100 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 157

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 158 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 215

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 274

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 275 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 331


>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
           isoform 3 [Homo sapiens]
          Length = 411

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 172 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 229

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 230 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 287

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 346

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 347 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 403


>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
           isoform 1 [Homo sapiens]
          Length = 420

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 181 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 238

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 239 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 296

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 355

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 356 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 412


>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
           isoform 8 [Homo sapiens]
          Length = 339

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 100 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 157

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 158 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 215

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 274

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 275 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 331


>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
           isoform 3 [Homo sapiens]
          Length = 411

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 172 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 229

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 230 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 287

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 346

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 347 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 403


>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
           isoform 1 [Homo sapiens]
          Length = 420

 Score =  185 bits (470), Expect = 1e-46
 Identities = 96/237 (40%), Positives = 136/237 (57%), Gaps = 8/237 (3%)

Query: 537 PQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ 596
           P N +KNRY+D+LPYD+TRV L  ++DYINASY+ +          YIATQGPL  T   
Sbjct: 181 PSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYF--YIATQGPLLSTIDD 238

Query: 597 FWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP---DPPDVMNHGGFHIQCQSEDCTIAYV 653
           FWQ+V +   ++I M+T   E G  KC+ YWP     P  + H  F +  ++      ++
Sbjct: 239 FWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH--FRVFLENYQILQYFI 296

Query: 654 SREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSA 713
            R   V    TG  H+V  LQ+  WPDHG P  +  F++++ Y R   +   P++VHCSA
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTG-PMVVHCSA 355

Query: 714 GIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
           GIGRTGV + ++   C   +N     +DIV +MR+QR+ MVQT  QY F  + +L V
Sbjct: 356 GIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV 412


>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
            precursor [Homo sapiens]
          Length = 1337

 Score =  182 bits (461), Expect = 1e-45
 Identities = 95/244 (38%), Positives = 136/244 (55%), Gaps = 12/244 (4%)

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLLQ----GNEDYINASYVNMEIPAANLVNKYIATQGP 589
            A+L +N  KNRY +VLPYD +RV L       +DYINA+Y+    P  +    +IATQGP
Sbjct: 1060 AELAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYM----PGYHSKKDFIATQGP 1115

Query: 590  LPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCT 649
            LP+T   FW++VW++ +  I+MLT   E+GRTKC +YWP      ++G   +   SE   
Sbjct: 1116 LPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPS-KQAQDYGDITVAMTSEIVL 1174

Query: 650  IAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDS---EP 706
              +  R+  V N QT E H +    + +WPDHGVPD +   + F   VR     S    P
Sbjct: 1175 PEWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQSPPESP 1234

Query: 707  VLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEA 766
            +LVHCSAG+GRTG  + ++  +   E    +    IV  +R  R +MVQT  QY F+ + 
Sbjct: 1235 ILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQC 1294

Query: 767  ILRV 770
            +L +
Sbjct: 1295 VLDI 1298


>gi|4506289 protein tyrosine phosphatase, non-receptor type 1 [Homo
           sapiens]
          Length = 435

 Score =  180 bits (457), Expect = 4e-45
 Identities = 99/268 (36%), Positives = 147/268 (54%), Gaps = 14/268 (5%)

Query: 511 ESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLL-QGNEDYINASY 569
           +SG+    ++ +  +        AKLP+N ++NRY+DV P+D +R+ L Q + DYINAS 
Sbjct: 12  KSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASL 71

Query: 570 VNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD 629
           + ME         YI TQGPLP+TC  FW++VW+QK   +VML  + E+G  KC QYWP 
Sbjct: 72  IKME----EAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQ 127

Query: 630 PPD---VMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDD 686
             +   +       +   SED    Y  R++ + N  T E   + H  Y  WPD GVP+ 
Sbjct: 128 KEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPES 187

Query: 687 SSDFLEFVNYVR---SLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIV 743
            + FL F+  VR   SL  +  PV+VHCSAGIGR+G     +T + L ++      +DI 
Sbjct: 188 PASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIK 247

Query: 744 R---KMRDQRAMMVQTSSQYKFVCEAIL 768
           +   +MR  R  ++QT+ Q +F   A++
Sbjct: 248 KVLLEMRKFRMGLIQTADQLRFSYLAVI 275


>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
           2 precursor [Homo sapiens]
          Length = 937

 Score =  179 bits (455), Expect = 7e-45
 Identities = 95/248 (38%), Positives = 135/248 (54%), Gaps = 12/248 (4%)

Query: 534 AKLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAANLVNKYIATQG 588
           A   +N  KNRY++VLPYD +RV L     +   DYINAS++    P      ++IATQG
Sbjct: 661 ASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFM----PGLWSPQEFIATQG 716

Query: 589 PLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDC 648
           PLP T   FW++VW+Q+   +VMLT   E GR KC  YWP       HG   +    E+ 
Sbjct: 717 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEV 776

Query: 649 TIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSE 705
              +  RE+L+   +  +  +V    Y AWPDHGVP      L F   +R      ++  
Sbjct: 777 MENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGG 836

Query: 706 PVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCE 765
           P +VHCSAG+GRTG L+ ++  +   +    + P   VRKMR+ R +MVQT +QY F+ +
Sbjct: 837 PPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQ 896

Query: 766 AILRVYEE 773
            ILR  ++
Sbjct: 897 CILRFLQQ 904


>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
            precursor [Homo sapiens]
          Length = 1115

 Score =  179 bits (455), Expect = 7e-45
 Identities = 95/248 (38%), Positives = 135/248 (54%), Gaps = 12/248 (4%)

Query: 534  AKLPQNLDKNRYKDVLPYDTTRVLL-----QGNEDYINASYVNMEIPAANLVNKYIATQG 588
            A   +N  KNRY++VLPYD +RV L     +   DYINAS++    P      ++IATQG
Sbjct: 839  ASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFM----PGLWSPQEFIATQG 894

Query: 589  PLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDC 648
            PLP T   FW++VW+Q+   +VMLT   E GR KC  YWP       HG   +    E+ 
Sbjct: 895  PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEV 954

Query: 649  TIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSE 705
               +  RE+L+   +  +  +V    Y AWPDHGVP      L F   +R      ++  
Sbjct: 955  MENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGG 1014

Query: 706  PVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCE 765
            P +VHCSAG+GRTG L+ ++  +   +    + P   VRKMR+ R +MVQT +QY F+ +
Sbjct: 1015 PPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQ 1074

Query: 766  AILRVYEE 773
             ILR  ++
Sbjct: 1075 CILRFLQQ 1082


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  177 bits (448), Expect = 4e-44
 Identities = 102/286 (35%), Positives = 149/286 (52%), Gaps = 16/286 (5%)

Query: 492  CPEGGDTLEGSMAQLKKGLESGTVLI-QFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLP 550
            CP   +  EG   +L+   +S  +L  ++E+L       +   A LP+N  KNRY ++LP
Sbjct: 1899 CPIKINQFEGHFMKLQA--DSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILP 1956

Query: 551  YDTTRVLLQGNED-----YINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQK 605
            YD TRV L   +D     YINASY    IP  N   +YI TQGPLP T   FW++VW+Q 
Sbjct: 1957 YDATRVKLSNVDDDPCSDYINASY----IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQN 2012

Query: 606  LSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTG 665
            +  IVM+T   E+GR KC  YWP   D + +G   +Q  SE     +  RE  +   +  
Sbjct: 2013 VHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQL 2072

Query: 666  EEH-TVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPVLVHCSAGIGRTGVL 721
            + H  + H  Y  WPDHGVP+ +   ++FV  VR   +    + P +VHCSAG+GRTG  
Sbjct: 2073 DAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTF 2132

Query: 722  VTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767
            + ++  +   +    +     V  +R  R  MVQT  QY ++ + +
Sbjct: 2133 IALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV 2178


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  177 bits (448), Expect = 4e-44
 Identities = 102/286 (35%), Positives = 149/286 (52%), Gaps = 16/286 (5%)

Query: 492  CPEGGDTLEGSMAQLKKGLESGTVLI-QFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLP 550
            CP   +  EG   +L+   +S  +L  ++E+L       +   A LP+N  KNRY ++LP
Sbjct: 1681 CPIKINQFEGHFMKLQA--DSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILP 1738

Query: 551  YDTTRVLLQGNED-----YINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQK 605
            YD TRV L   +D     YINASY    IP  N   +YI TQGPLP T   FW++VW+Q 
Sbjct: 1739 YDATRVKLSNVDDDPCSDYINASY----IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQN 1794

Query: 606  LSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTG 665
            +  IVM+T   E+GR KC  YWP   D + +G   +Q  SE     +  RE  +   +  
Sbjct: 1795 VHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQL 1854

Query: 666  EEH-TVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPVLVHCSAGIGRTGVL 721
            + H  + H  Y  WPDHGVP+ +   ++FV  VR   +    + P +VHCSAG+GRTG  
Sbjct: 1855 DAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTF 1914

Query: 722  VTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767
            + ++  +   +    +     V  +R  R  MVQT  QY ++ + +
Sbjct: 1915 IALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV 1960


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
            isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score =  173 bits (439), Expect = 5e-43
 Identities = 105/277 (37%), Positives = 151/277 (54%), Gaps = 19/277 (6%)

Query: 503  MAQLKKGLESGTVLIQFEQLYRKKPGLAITF--AKLPQNLDKNRYKDVLPYDTTRVLLQG 560
            MA+  + L++   L   ++     PG   T+  + L  N  KNRY +V+ YD +RV+LQ 
Sbjct: 935  MAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQP 994

Query: 561  NE-----DYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTL 615
             E     DYINA+YV+         N YIATQGPLP T   FW++VW+Q+ + IVM+T L
Sbjct: 995  IEGIMGSDYINANYVD----GYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRL 1050

Query: 616  TERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQY 675
             E+ R KC QYWP+      +G   +          +  R   +    + E+  V   Q+
Sbjct: 1051 EEKSRIKCDQYWPN-RGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1109

Query: 676  VAWPDHGVPDDSSDFLEFVNYVRSLR-VDSEPVLVHCSAGIGRTGVLVTMETAMCLTERN 734
             AWPDHGVP+  + FL F+  V++    D+ P++VHCSAG+GRTG  + ++    + ER 
Sbjct: 1110 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVID---AMLERI 1166

Query: 735  LPIYPLDI---VRKMRDQRAMMVQTSSQYKFVCEAIL 768
             P   +D+   V  MR QR  MVQT  QY F+ EA+L
Sbjct: 1167 KPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALL 1203



 Score =  171 bits (434), Expect = 2e-42
 Identities = 97/275 (35%), Positives = 145/275 (52%), Gaps = 14/275 (5%)

Query: 503  MAQLKKGLESGTVLIQFEQLYRKKPGLA-ITFAKLPQNLDKNRYKDVLPYDTTRVLLQG- 560
            +AQ++ G     + ++F++L   K   +    A LP N  KNR  +++PY++TRV LQ  
Sbjct: 1225 LAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPI 1284

Query: 561  ----NEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLT 616
                  DYINAS+++           YIATQGPL  T   FW+++W+   +++VMLT L 
Sbjct: 1285 RGVEGSDYINASFID----GYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLR 1340

Query: 617  ERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYV 676
            E GR KCHQYWP       +  F +   +E     Y+ RE  VT+ + G+  TV   Q+ 
Sbjct: 1341 EMGREKCHQYWPAERSA-RYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFT 1399

Query: 677  AWPDHGVPDDSSDFLEFVNYVRSLRV---DSEPVLVHCSAGIGRTGVLVTMETAMCLTER 733
             WP+ GVP     F++F+  V   +       P+ VHCSAG+GRTGV +T+   +     
Sbjct: 1400 DWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRY 1459

Query: 734  NLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAIL 768
               +     V+ +R QR  MVQT  +Y+F  +A L
Sbjct: 1460 EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAAL 1494


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  173 bits (439), Expect = 5e-43
 Identities = 105/277 (37%), Positives = 151/277 (54%), Gaps = 19/277 (6%)

Query: 503  MAQLKKGLESGTVLIQFEQLYRKKPGLAITF--AKLPQNLDKNRYKDVLPYDTTRVLLQG 560
            MA+  + L++   L   ++     PG   T+  + L  N  KNRY +V+ YD +RV+LQ 
Sbjct: 1340 MAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQP 1399

Query: 561  NE-----DYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTL 615
             E     DYINA+YV+         N YIATQGPLP T   FW++VW+Q+ + IVM+T L
Sbjct: 1400 IEGIMGSDYINANYVD----GYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRL 1455

Query: 616  TERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQY 675
             E+ R KC QYWP+      +G   +          +  R   +    + E+  V   Q+
Sbjct: 1456 EEKSRIKCDQYWPN-RGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1514

Query: 676  VAWPDHGVPDDSSDFLEFVNYVRSLR-VDSEPVLVHCSAGIGRTGVLVTMETAMCLTERN 734
             AWPDHGVP+  + FL F+  V++    D+ P++VHCSAG+GRTG  + ++    + ER 
Sbjct: 1515 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVID---AMLERI 1571

Query: 735  LPIYPLDI---VRKMRDQRAMMVQTSSQYKFVCEAIL 768
             P   +D+   V  MR QR  MVQT  QY F+ EA+L
Sbjct: 1572 KPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALL 1608



 Score =  171 bits (434), Expect = 2e-42
 Identities = 97/275 (35%), Positives = 145/275 (52%), Gaps = 14/275 (5%)

Query: 503  MAQLKKGLESGTVLIQFEQLYRKKPGLA-ITFAKLPQNLDKNRYKDVLPYDTTRVLLQG- 560
            +AQ++ G     + ++F++L   K   +    A LP N  KNR  +++PY++TRV LQ  
Sbjct: 1630 LAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPI 1689

Query: 561  ----NEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLT 616
                  DYINAS+++           YIATQGPL  T   FW+++W+   +++VMLT L 
Sbjct: 1690 RGVEGSDYINASFID----GYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLR 1745

Query: 617  ERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYV 676
            E GR KCHQYWP       +  F +   +E     Y+ RE  VT+ + G+  TV   Q+ 
Sbjct: 1746 EMGREKCHQYWPAERSA-RYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFT 1804

Query: 677  AWPDHGVPDDSSDFLEFVNYVRSLRV---DSEPVLVHCSAGIGRTGVLVTMETAMCLTER 733
             WP+ GVP     F++F+  V   +       P+ VHCSAG+GRTGV +T+   +     
Sbjct: 1805 DWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRY 1864

Query: 734  NLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAIL 768
               +     V+ +R QR  MVQT  +Y+F  +A L
Sbjct: 1865 EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAAL 1899


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,600,355
Number of Sequences: 37866
Number of extensions: 1399018
Number of successful extensions: 5171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 4243
Number of HSP's gapped (non-prelim): 531
length of query: 782
length of database: 18,247,518
effective HSP length: 110
effective length of query: 672
effective length of database: 14,082,258
effective search space: 9463277376
effective search space used: 9463277376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.