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Search of human proteins with 223468681
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog
A isoform 2 [Homo sapiens]
(548 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 1119 0.0
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 1113 0.0
gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [H... 375 e-104
gi|35493878 reticuloendotheliosis viral oncogene homolog B [Homo... 320 3e-87
gi|117320531 nuclear factor of kappa light polypeptide gene enha... 246 5e-65
gi|117320540 nuclear factor of kappa light polypeptide gene enha... 246 5e-65
gi|117320527 nuclear factor of kappa light polypeptide gene enha... 246 5e-65
gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens] 234 1e-61
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 68 2e-11
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 68 2e-11
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 68 2e-11
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 62 2e-09
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 62 2e-09
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 62 2e-09
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 62 2e-09
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 62 2e-09
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 61 2e-09
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 61 2e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 59 1e-08
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 59 1e-08
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 57 6e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 55 1e-07
gi|45120115 hypothetical protein LOC56905 [Homo sapiens] 55 1e-07
gi|153792074 proline rich 12 [Homo sapiens] 55 1e-07
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 55 2e-07
gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 55 2e-07
gi|108796058 ral guanine nucleotide dissociation stimulator isof... 55 2e-07
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 54 4e-07
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 52 1e-06
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 52 1e-06
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 1119 bits (2894), Expect = 0.0
Identities = 548/548 (100%), Positives = 548/548 (100%)
Query: 1 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 60
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
Sbjct: 1 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 60
Query: 61 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 120
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
Sbjct: 61 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 120
Query: 121 VKKRDLEQAISQRIQTNNNPFQEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPI 180
VKKRDLEQAISQRIQTNNNPFQEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPI
Sbjct: 121 VKKRDLEQAISQRIQTNNNPFQEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPI 180
Query: 181 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQAD 240
FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQAD
Sbjct: 181 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQAD 240
Query: 241 VHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRK 300
VHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRK
Sbjct: 241 VHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRK 300
Query: 301 RTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEF 360
RTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEF
Sbjct: 301 RTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEF 360
Query: 361 PTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP 420
PTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP
Sbjct: 361 PTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP 420
Query: 421 PAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIP 480
PAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIP
Sbjct: 421 PAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIP 480
Query: 481 VAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFS 540
VAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFS
Sbjct: 481 VAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFS 540
Query: 541 ALLSQISS 548
ALLSQISS
Sbjct: 541 ALLSQISS 548
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 1113 bits (2880), Expect = 0.0
Identities = 548/551 (99%), Positives = 548/551 (99%), Gaps = 3/551 (0%)
Query: 1 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 60
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
Sbjct: 1 MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT 60
Query: 61 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 120
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
Sbjct: 61 IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC 120
Query: 121 VKKRDLEQAISQRIQTNNNPFQ---EEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 177
VKKRDLEQAISQRIQTNNNPFQ EEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
Sbjct: 121 VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS 180
Query: 178 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 237
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
Sbjct: 181 HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS 240
Query: 238 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 297
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
Sbjct: 241 QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE 300
Query: 298 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 357
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
Sbjct: 301 KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY 360
Query: 358 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 417
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
Sbjct: 361 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 420
Query: 418 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 477
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
Sbjct: 421 VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ 480
Query: 478 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 537
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
Sbjct: 481 GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM 540
Query: 538 DFSALLSQISS 548
DFSALLSQISS
Sbjct: 541 DFSALLSQISS 551
>gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [Homo
sapiens]
Length = 619
Score = 375 bits (963), Expect = e-104
Identities = 211/427 (49%), Positives = 273/427 (63%), Gaps = 28/427 (6%)
Query: 16 ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRIS 75
A PY+EIIEQP+QRGMRFRYKCEGRSAGSIPGE STD +T+P+I+I Y G G VRI+
Sbjct: 5 AYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGKVRIT 64
Query: 76 LVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQ 135
LVTK+ P++PHPH+LVGKDCRDG+YEAE +R FQNLGI+CVKK+++++AI RI+
Sbjct: 65 LVTKNDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAIITRIK 124
Query: 136 TNNNPFQEEQR-----GDYDLNAVRLCFQVTVRDPSGR-PLRLPPVLSHPIFDNRAPNTA 189
NPF ++ D DLN VRLCFQV + D G LPPV+S+PI+DNRAPNTA
Sbjct: 125 AGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPDEHGNLTTALPPVVSNPIYDNRAPNTA 184
Query: 190 ELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVF 249
EL+ICRVN+N GS GGDEIFLLCDKVQK+DIEV F WEA+G FSQADVHRQVAIVF
Sbjct: 185 ELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQVAIVF 244
Query: 250 RTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSI 309
+TPPY ++ PV V MQLRRPSD+E+SE M+F+YLPD D + + K+++T F+ +
Sbjct: 245 KTPPYC-KAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQKL 303
Query: 310 MKKSPFSG-----------PTDPRPPPRRIAVPSRSSASVPKPAPQPYP-FTSSLSTINY 357
+ +G T PP + S+S+ +P P S+ Y
Sbjct: 304 CQDHVETGFRHVDQDGLELLTSGDPP----TLASQSAGITVNFPERPRPGLLGSIGEGRY 359
Query: 358 DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA 417
+ +F S + + P V QA + P+P +S+ A + L +
Sbjct: 360 FKKEPNLF-----SHDAVVREMPTGVSSQAESYYPSPGPISSGLSHHASMAPLPSSSWSS 414
Query: 418 VAPPAPK 424
VA P P+
Sbjct: 415 VAHPTPR 421
>gi|35493878 reticuloendotheliosis viral oncogene homolog B [Homo
sapiens]
Length = 579
Score = 320 bits (819), Expect = 3e-87
Identities = 186/422 (44%), Positives = 245/422 (58%), Gaps = 30/422 (7%)
Query: 7 LIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGY 66
L+ PA P P++ I EQPKQRGMRFRY+CEGRSAGSI GE ST+ +KT P I++
Sbjct: 114 LVSPA-PGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDC 172
Query: 67 TGPGTVRIS--LVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCI-HSFQNLGIQCVKK 123
G V ++ LV KD PHR HPH LVGKDC DG L P HSF NLGIQCV+K
Sbjct: 173 GGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSPRHSFNNLGIQCVRK 232
Query: 124 RDLEQAISQRIQTNNNPFQE---EQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPI 180
+++E AI ++IQ +P+ + + D+N VR+CFQ + RD G+ R+ PVLS P+
Sbjct: 233 KEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPV 292
Query: 181 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQAD 240
+D ++ NT+EL+ICR+N+ SG C GG+E++LLCDKVQKEDI V F+ WE R FSQAD
Sbjct: 293 YDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQAD 352
Query: 241 VHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRK 300
VHRQ+AIVF+TPPY D + PV V++ L+R +D SEP+ F YLP D + +++KRK
Sbjct: 353 VHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRK 412
Query: 301 RTYETFKSIMKKSPFSGPTDPR--PPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358
R + S DP RR P+ +P P+ S+L
Sbjct: 413 RGMPDVLGELNSS------DPHGIESKRRKKKPAILDHFLPNHGSGPFLPPSAL------ 460
Query: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP-APAMVSALAQAPAPVPVLAPGPPQA 417
P F SG +S P P +L A P AP + + L +L P PP A
Sbjct: 461 -LPDPDFFSGTVSLPGLEPPGGPDLLDDGFAYDPTAPTLFTML-------DLLPPAPPHA 512
Query: 418 VA 419
A
Sbjct: 513 SA 514
>gi|117320531 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform a [Homo sapiens]
Length = 900
Score = 246 bits (627), Expect = 5e-65
Identities = 139/334 (41%), Positives = 188/334 (56%), Gaps = 28/334 (8%)
Query: 7 LIFPAEPAQ--ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKIN 64
++ P EPA A GPY+ I+EQPKQRG RFRY CEG S G +PG S KT+PT+KI
Sbjct: 24 IVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKIC 83
Query: 65 GYTGPGTVRISLVTKDPPHRPHPHELVGKDCRD-GFYEAELCPDRCIHSFQNLGIQCVKK 123
Y GP + + LVT P R H H LVGK C + G + P F NLG+ V K
Sbjct: 84 NYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTK 143
Query: 124 RDLEQAISQRIQ-----------TNNNPFQEEQRGD-----YDLNAVRLCFQVTVRDPSG 167
+++ + Q++Q T + EQ DL+ VRL F +R G
Sbjct: 144 KNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDG 203
Query: 168 R-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYF- 225
L L PV+S PI D+++P + LKI R+++ +GS GGDE++LLCDKVQK+DIEV F
Sbjct: 204 SFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFY 263
Query: 226 --TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEF 283
GW+A G FS DVH+Q AIVFRTPPY ++ PV V +QL+R ++S+ +F
Sbjct: 264 EDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQF 323
Query: 284 QYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSG 317
Y P +D+ ++ KR++ TF PF G
Sbjct: 324 TYYPLVEDKEEVQRKRRKALPTF-----SQPFGG 352
>gi|117320540 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 246 bits (627), Expect = 5e-65
Identities = 139/334 (41%), Positives = 188/334 (56%), Gaps = 28/334 (8%)
Query: 7 LIFPAEPAQ--ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKIN 64
++ P EPA A GPY+ I+EQPKQRG RFRY CEG S G +PG S KT+PT+KI
Sbjct: 24 IVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKIC 83
Query: 65 GYTGPGTVRISLVTKDPPHRPHPHELVGKDCRD-GFYEAELCPDRCIHSFQNLGIQCVKK 123
Y GP + + LVT P R H H LVGK C + G + P F NLG+ V K
Sbjct: 84 NYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTK 143
Query: 124 RDLEQAISQRIQ-----------TNNNPFQEEQRGD-----YDLNAVRLCFQVTVRDPSG 167
+++ + Q++Q T + EQ DL+ VRL F +R G
Sbjct: 144 KNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDG 203
Query: 168 R-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYF- 225
L L PV+S PI D+++P + LKI R+++ +GS GGDE++LLCDKVQK+DIEV F
Sbjct: 204 SFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFY 263
Query: 226 --TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEF 283
GW+A G FS DVH+Q AIVFRTPPY ++ PV V +QL+R ++S+ +F
Sbjct: 264 EDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQF 323
Query: 284 QYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSG 317
Y P +D+ ++ KR++ TF PF G
Sbjct: 324 TYYPLVEDKEEVQRKRRKALPTF-----SQPFGG 352
>gi|117320527 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 246 bits (627), Expect = 5e-65
Identities = 139/334 (41%), Positives = 188/334 (56%), Gaps = 28/334 (8%)
Query: 7 LIFPAEPAQ--ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKIN 64
++ P EPA A GPY+ I+EQPKQRG RFRY CEG S G +PG S KT+PT+KI
Sbjct: 24 IVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKIC 83
Query: 65 GYTGPGTVRISLVTKDPPHRPHPHELVGKDCRD-GFYEAELCPDRCIHSFQNLGIQCVKK 123
Y GP + + LVT P R H H LVGK C + G + P F NLG+ V K
Sbjct: 84 NYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTK 143
Query: 124 RDLEQAISQRIQ-----------TNNNPFQEEQRGD-----YDLNAVRLCFQVTVRDPSG 167
+++ + Q++Q T + EQ DL+ VRL F +R G
Sbjct: 144 KNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDG 203
Query: 168 R-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYF- 225
L L PV+S PI D+++P + LKI R+++ +GS GGDE++LLCDKVQK+DIEV F
Sbjct: 204 SFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFY 263
Query: 226 --TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEF 283
GW+A G FS DVH+Q AIVFRTPPY ++ PV V +QL+R ++S+ +F
Sbjct: 264 EDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQF 323
Query: 284 QYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSG 317
Y P +D+ ++ KR++ TF PF G
Sbjct: 324 TYYPLVEDKEEVQRKRRKALPTF-----SQPFGG 352
>gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]
Length = 969
Score = 234 bits (598), Expect = 1e-61
Identities = 139/344 (40%), Positives = 181/344 (52%), Gaps = 43/344 (12%)
Query: 6 PLIFPAEPA--QASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKI 63
P +F + A A GPY++I+EQPKQRG RFRY CEG S G +PG S K++P +KI
Sbjct: 28 PEVFQPQMALPTADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKI 87
Query: 64 NGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKK 123
Y GP V + LVT H H LVGK C DG P + F NLGI V K
Sbjct: 88 CNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTK 147
Query: 124 RDLEQAISQRIQT----NNNP----------FQEEQRGD--------------------- 148
+ + + + R+ NP Q E GD
Sbjct: 148 KKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKE 207
Query: 149 YDLNAVRLCFQVTVRDPSGR-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGD 207
DL+ VRL F + D +G RL PV+S I+D++APN + LKI R++R +G GG+
Sbjct: 208 MDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGE 267
Query: 208 EIFLLCDKVQKEDIEVYF-----TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAP 262
EI+LLCDKVQK+DI++ F G WE G FS DVHRQ AIVF+TP Y D ++ P
Sbjct: 268 EIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKP 327
Query: 263 VRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETF 306
V +QLRR SD E SEP F Y P+ D+ ++ KR++ F
Sbjct: 328 ASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNF 371
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 68.2 bits (165), Expect = 2e-11
Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
++++P P+ P P P P A P PAP P
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV----------------------- 154
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 429
A AP VL APAPAPAPA A APAP P AP P A PAP P A
Sbjct: 155 --AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 209
Query: 430 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 487
+ + + Q Q E L L G S PA T AS + + ++L P+
Sbjct: 210 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 266
Query: 488 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 520
PE + V P P P+P APG+
Sbjct: 267 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 293
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 308 SIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYP 347
+++ +P P P P P +A P+ + A P PAP P P
Sbjct: 165 AVLAPAPAPAPA-PAPAPAPVAAPAPAPAPAPAPAPAPAP 203
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 68.2 bits (165), Expect = 2e-11
Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
++++P P+ P P P P A P PAP P
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV----------------------- 154
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 429
A AP VL APAPAPAPA A APAP P AP P A PAP P A
Sbjct: 155 --AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 209
Query: 430 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 487
+ + + Q Q E L L G S PA T AS + + ++L P+
Sbjct: 210 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 266
Query: 488 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 520
PE + V P P P+P APG+
Sbjct: 267 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 293
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 308 SIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYP 347
+++ +P P P P P +A P+ + A P PAP P P
Sbjct: 165 AVLAPAPAPAPA-PAPAPAPVAAPAPAPAPAPAPAPAPAP 203
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 68.2 bits (165), Expect = 2e-11
Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 39/213 (18%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
++++P P+ P P P P A P PAP P
Sbjct: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV----------------------- 165
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAG 429
A AP VL APAPAPAPA A APAP P AP P A PAP P A
Sbjct: 166 --AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA---PAPAPDAAP 220
Query: 430 EGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTE 487
+ + + Q Q E L L G S PA T AS + + ++L P+
Sbjct: 221 QESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG---PLISDFFA 277
Query: 488 PMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGL 520
PE + V P P P+P APG+
Sbjct: 278 KRKRSAPEKSSGDV------PAPCPSPSAAPGV 304
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 308 SIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYP 347
+++ +P P P P P +A P+ + A P PAP P P
Sbjct: 176 AVLAPAPAPAPA-PAPAPAPVAAPAPAPAPAPAPAPAPAP 214
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 61.6 bits (148), Expect = 2e-09
Identities = 118/497 (23%), Positives = 179/497 (36%), Gaps = 78/497 (15%)
Query: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
Query: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
D RPH H + GK +EA L + + I + + +
Sbjct: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
Query: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184
I I N E ++G+ D+ VRL F+V V PSGR L L V S+PI ++
Sbjct: 518 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 576
Query: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238
+ EL + + G + +L +D +V F WE +
Sbjct: 577 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 634
Query: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298
D+ + ++V PP+ + + +PV VS + R+ S+ F YLP + E
Sbjct: 635 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 691
Query: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358
PTD P S+ + P P P+ S + D
Sbjct: 692 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 726
Query: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416
+V Q S L PA P V P+ +PA V++ +P A P
Sbjct: 727 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 786
Query: 417 AVAPPAPKPTQAGE-GTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLL 475
P P T G G ALL Q + A +S P + L S
Sbjct: 787 VQDVPRPVATHPGSPGQPPPALLPQQ-----VSAPPSSSCPPGLEHSLCPSSPSP----- 836
Query: 476 NQGIPVAPHTTEPMLME 492
P+ P T EP ++
Sbjct: 837 ----PLPPATQEPTCLQ 849
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 61.6 bits (148), Expect = 2e-09
Identities = 102/428 (23%), Positives = 166/428 (38%), Gaps = 47/428 (10%)
Query: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
Query: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Query: 120 CVKKRDLEQAIS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPP 174
+ + ++ +I I N E ++G+ D+ VRL F+V + PSG+ L L
Sbjct: 525 LLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL-Q 583
Query: 175 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT-----GPG 229
+ S P+ ++ I + + NS S GG E+ + E ++ P
Sbjct: 584 IASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQ 643
Query: 230 WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDT 289
WE G + + + IV PPY +P++ A V+V L R+ S+ F Y P
Sbjct: 644 WEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTYTP-- 699
Query: 290 DDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFT 349
+ K++ E S + P P + P S S + P T
Sbjct: 700 -----VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQT 754
Query: 350 SSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA 403
+ S + P + +S+ + P+P P P P P + +
Sbjct: 755 YA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
Query: 404 PAPVPVLA 411
P +P+ A
Sbjct: 814 PTCLPINA 821
Score = 30.4 bits (67), Expect = 4.4
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 342
+ SP SGP P+ P PS +AS P PA
Sbjct: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 61.6 bits (148), Expect = 2e-09
Identities = 102/428 (23%), Positives = 166/428 (38%), Gaps = 47/428 (10%)
Query: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
Query: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Query: 120 CVKKRDLEQAIS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPP 174
+ + ++ +I I N E ++G+ D+ VRL F+V + PSG+ L L
Sbjct: 525 LLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL-Q 583
Query: 175 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT-----GPG 229
+ S P+ ++ I + + NS S GG E+ + E ++ P
Sbjct: 584 IASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQ 643
Query: 230 WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDT 289
WE G + + + IV PPY +P++ A V+V L R+ S+ F Y P
Sbjct: 644 WEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTYTP-- 699
Query: 290 DDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFT 349
+ K++ E S + P P + P S S + P T
Sbjct: 700 -----VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQT 754
Query: 350 SSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA 403
+ S + P + +S+ + P+P P P P P + +
Sbjct: 755 YA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
Query: 404 PAPVPVLA 411
P +P+ A
Sbjct: 814 PTCLPINA 821
Score = 30.4 bits (67), Expect = 4.4
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 342
+ SP SGP P+ P PS +AS P PA
Sbjct: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 61.6 bits (148), Expect = 2e-09
Identities = 102/428 (23%), Positives = 166/428 (38%), Gaps = 47/428 (10%)
Query: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
Query: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Query: 120 CVKKRDLEQAIS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPP 174
+ + ++ +I I N E ++G+ D+ VRL F+V + PSG+ L L
Sbjct: 525 LLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL-Q 583
Query: 175 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT-----GPG 229
+ S P+ ++ I + + NS S GG E+ + E ++ P
Sbjct: 584 IASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQ 643
Query: 230 WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDT 289
WE G + + + IV PPY +P++ A V+V L R+ S+ F Y P
Sbjct: 644 WEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTYTP-- 699
Query: 290 DDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFT 349
+ K++ E S + P P + P S S + P T
Sbjct: 700 -----VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQT 754
Query: 350 SSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA 403
+ S + P + +S+ + P+P P P P P + +
Sbjct: 755 YA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
Query: 404 PAPVPVLA 411
P +P+ A
Sbjct: 814 PTCLPINA 821
Score = 30.4 bits (67), Expect = 4.4
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 342
+ SP SGP P+ P PS +AS P PA
Sbjct: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 61.6 bits (148), Expect = 2e-09
Identities = 102/428 (23%), Positives = 166/428 (38%), Gaps = 47/428 (10%)
Query: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
Query: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Query: 120 CVKKRDLEQAIS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPP 174
+ + ++ +I I N E ++G+ D+ VRL F+V + PSG+ L L
Sbjct: 525 LLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL-Q 583
Query: 175 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT-----GPG 229
+ S P+ ++ I + + NS S GG E+ + E ++ P
Sbjct: 584 IASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQ 643
Query: 230 WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDT 289
WE G + + + IV PPY +P++ A V+V L R+ S+ F Y P
Sbjct: 644 WEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTYTP-- 699
Query: 290 DDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFT 349
+ K++ E S + P P + P S S + P T
Sbjct: 700 -----VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQT 754
Query: 350 SSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA 403
+ S + P + +S+ + P+P P P P P + +
Sbjct: 755 YA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
Query: 404 PAPVPVLA 411
P +P+ A
Sbjct: 814 PTCLPINA 821
Score = 30.4 bits (67), Expect = 4.4
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 342
+ SP SGP P+ P PS +AS P PA
Sbjct: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 61.2 bits (147), Expect = 2e-09
Identities = 108/446 (24%), Positives = 163/446 (36%), Gaps = 64/446 (14%)
Query: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
Query: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
D RPH H + GK +EA L + + I + + +
Sbjct: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
Query: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184
I I N E ++G+ D+ VRL F+V V PSGR L L V S+PI ++
Sbjct: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 589
Query: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238
+ EL + + G + +L +D +V F WE +
Sbjct: 590 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 647
Query: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298
D+ + ++V PP+ + + +PV VS + R+ S+ F YLP + E
Sbjct: 648 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 704
Query: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358
PTD P S+ + P P P+ S + D
Sbjct: 705 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 739
Query: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416
+V Q S L PA P V P+ +PA V++ +P A P
Sbjct: 740 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 799
Query: 417 AVAPPAPKPTQAGE-GTLSEALLQLQ 441
P P T G G ALL Q
Sbjct: 800 VQDVPRPVATHPGSPGQPPPALLPQQ 825
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 61.2 bits (147), Expect = 2e-09
Identities = 108/446 (24%), Positives = 163/446 (36%), Gaps = 64/446 (14%)
Query: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 410 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 463
Query: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
D RPH H + GK +EA L + + I + + +
Sbjct: 464 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 517
Query: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184
I I N E ++G+ D+ VRL F+V V PSGR L L V S+PI ++
Sbjct: 518 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQ-VASNPIECSQ 576
Query: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238
+ EL + + G + +L +D +V F WE +
Sbjct: 577 R-SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 634
Query: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEK 298
D+ + ++V PP+ + + +PV VS + R+ S+ F YLP + E
Sbjct: 635 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLPANVPIIKTE-- 691
Query: 299 RKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYD 358
PTD P S+ + P P P+ S + D
Sbjct: 692 -------------------PTDDYEPAPTCGPVSQGLS------PLPRPYYSQQLAMPPD 726
Query: 359 EFPTMVFPSGQISQASALAPAPPQVLPQAP--APAPAPAMVSALAQAPAPVPVLAPGPPQ 416
+V Q S L PA P V P+ +PA V++ +P A P
Sbjct: 727 PSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPA 786
Query: 417 AVAPPAPKPTQAGE-GTLSEALLQLQ 441
P P T G G ALL Q
Sbjct: 787 VQDVPRPVATHPGSPGQPPPALLPQQ 812
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 58.9 bits (141), Expect = 1e-08
Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 22/138 (15%)
Query: 314 PFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYP---------------FTSSLSTINYD 358
P G T P PP P+ ++A+ P P P P P ++ +T
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS 161
Query: 359 EFPTMVFPSGQISQASALAP----APPQVLPQA-PAPAPAPAMVSALAQAPAPVPVLAPG 413
P P Q + A P APP V P A P AP PA+ A + P P P P
Sbjct: 162 PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAV--AAREPPLPPPPQPPA 219
Query: 414 PPQAVAPPAPKPTQAGEG 431
PPQ PP P+P EG
Sbjct: 220 PPQQQQPPPPQPQPPPEG 237
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/105 (31%), Positives = 39/105 (37%), Gaps = 18/105 (17%)
Query: 343 PQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQ 402
P+P + L + V G IS +A PP+ PAP AP A A
Sbjct: 64 PEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAA 123
Query: 403 APAPVPVLAPGPP------------------QAVAPPAPKPTQAG 429
A AP P AP PP A APP+P P Q G
Sbjct: 124 AAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 58.5 bits (140), Expect = 1e-08
Identities = 44/119 (36%), Positives = 56/119 (47%), Gaps = 19/119 (15%)
Query: 325 PRRIAVPSRSSASVPKPAPQPYPFTSSLST---INYDEFPTMVFPSGQISQASALAPAPP 381
P + + +S+S P AP P P +S+ST + ++ + ++ SA PAP
Sbjct: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879
Query: 382 QVLPQAPA------PAPAP------AMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQA 428
P AP PA AP A SA A APAP PV AP P APPAP TQA
Sbjct: 1880 ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNP----APPAPAQTQA 1934
Score = 53.5 bits (127), Expect = 5e-07
Identities = 69/248 (27%), Positives = 88/248 (35%), Gaps = 46/248 (18%)
Query: 296 EEKRKRTYETFKSIMKKSPFS-GPTDPRPPPRRIAVP-------SRSSASVPKPAPQPYP 347
EE+RK+ + + KK+ G + P R A ++SSASVP A P P
Sbjct: 1696 EERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLP 1755
Query: 348 FTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLP---QAPAPAPAPAMVSALAQAP 404
++S S AS AP P + P AP PA + LA
Sbjct: 1756 PSTSASV-----------------PASTSAPLPATLTPVPASTSAPVPASTLAPVLASTS 1798
Query: 405 APVPVLAPGPPQA---VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFT 461
APVP P A V+ P T A T S A +L + + PA T
Sbjct: 1799 APVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPT----PILASVSTPASVT 1854
Query: 462 DLASVDNSEFQQLLNQ----------GIPVAPHTTEPML-MEYPEAITRLVTGAQRPPDP 510
LAS L P AP T P + P A L + P P
Sbjct: 1855 ILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAP 1914
Query: 511 APAPLGAP 518
AP P+ AP
Sbjct: 1915 APTPVSAP 1922
Score = 31.6 bits (70), Expect = 2.0
Identities = 53/220 (24%), Positives = 79/220 (35%), Gaps = 43/220 (19%)
Query: 313 SPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQ 372
+P S P +P PP P+++ A KP P TS S P++ PS Q
Sbjct: 1917 TPVSAP-NPAPP-----APAQTQAQTHKPVQNPLQTTSQSSK---QPPPSIRLPSAQTPN 1967
Query: 373 ASALAPAPPQV-LPQAPAPAPA---------PAMVSALAQAPAPVPVLAPGPPQAVAPPA 422
+ + + PQ+ A PA+++ +++ P+ P PP A
Sbjct: 1968 GTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPIS--PPQPPSVSAWNK 2025
Query: 423 PKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVA 482
P T G SE Q ++G TD F AS N N+ +PV
Sbjct: 2026 PL-TSFGSAPSSEGAKNGQESGLEIG------TDTIQFGAPASNGNE------NEVVPVL 2072
Query: 483 PHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPN 522
+ + E E QR P P+ A LP+
Sbjct: 2073 SEKSADKIPEPKE---------QRQKQPRAGPIKAQKLPD 2103
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 56.6 bits (135), Expect = 6e-08
Identities = 51/136 (37%), Positives = 60/136 (44%), Gaps = 34/136 (25%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTS------SLSTINYDEFPTMVF--------- 365
P P P VP + + SVP P+P P + S+ T+ D P V
Sbjct: 228 PAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPA 287
Query: 366 ---PSGQIS-QASALAP------APPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAP--- 412
PSG + A A AP APP L QAP P AP +V AP P PVLAP
Sbjct: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLV----LAPVPTPVLAPMPA 343
Query: 413 -GPPQAVAPPA-PKPT 426
PP A APP+ P PT
Sbjct: 344 STPPAAPAPPSVPMPT 359
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/213 (28%), Positives = 73/213 (34%), Gaps = 27/213 (12%)
Query: 319 TDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQIS-QASALA 377
T+ P P I P+ SASVP P + S+ P V SG + Q +
Sbjct: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSV--------PAPVPHSGLVPVQVATSV 245
Query: 378 PAPPQVLPQAPAPAPAPAMVSALAQAPAP--------VPVLAPGPPQAVAP---PAPKPT 426
PAP L PA APAP V L P VPV A PP P PAP P
Sbjct: 246 PAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPL 305
Query: 427 QAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTT 486
AL+Q +L P + AS + P P T
Sbjct: 306 SVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAA------PAPPSVPMPT 359
Query: 487 EPMLMEYPEAITRLVTGAQRP-PDPAPAPLGAP 518
P T + A P P P PAP+ P
Sbjct: 360 PTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTP 392
Score = 50.8 bits (120), Expect = 3e-06
Identities = 41/119 (34%), Positives = 48/119 (40%), Gaps = 11/119 (9%)
Query: 313 SPFSGPTD---PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
+P SGP P P P + V + A + P P P T+ PT V
Sbjct: 289 APPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAP------TLVLAPVPTPVLAPMP 342
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQA 428
S A APAPP V P P+ P L A AP PV AP P + PAP P A
Sbjct: 343 ASTPPA-APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAP-TPAPIFTPAPTPMPA 399
Score = 43.5 bits (101), Expect = 5e-04
Identities = 71/273 (26%), Positives = 97/273 (35%), Gaps = 52/273 (19%)
Query: 323 PPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQ 382
P P + P +S PAP P + + PT++ P+ + A PAP
Sbjct: 332 PVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLI-PAFAPTPVPAPTPAPIF 390
Query: 383 VLPQAPAPAPAPAMVSA----------------LAQAPA---------PVPVLAPGPPQA 417
P PA PA + AQAPA P VL P P
Sbjct: 391 TPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLV 450
Query: 418 VAPP---------APKPTQAG-EGTLSEALLQLQFDDEDLGALLGN---STDPAVFTDLA 464
PP A PT G TL+ +L D L +L + + P F+
Sbjct: 451 YIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVAR 510
Query: 465 SV-DNSEFQQL----LNQGIPVAPHTTEPML--MEYPEAITRLVTGAQR------PPDPA 511
+ +S+ L L P TT+P + P A T LVT + + P PA
Sbjct: 511 PLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPA 570
Query: 512 PAPLGAPGLPNGLLSGDEDFSSIADMDFSALLS 544
P+ AP P + SG E + + FS L S
Sbjct: 571 PSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKS 603
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/114 (28%), Positives = 42/114 (36%), Gaps = 5/114 (4%)
Query: 313 SPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQ 372
+P S P PP I P SA AP P P + + P
Sbjct: 303 APLSVPVSA-PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPT 361
Query: 373 ASALAPAPPQVLPQ-APAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKP 425
S+ P+ P ++P AP P PAP AP P+P P A+ AP P
Sbjct: 362 PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPA---AIPTSAPIP 412
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/216 (28%), Positives = 83/216 (38%), Gaps = 22/216 (10%)
Query: 328 IAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQIS--QASALAPAPPQVLP 385
+ VP+ + AS AP P P +SL + P ++ Q + LAP+P L
Sbjct: 1548 VLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLA 1607
Query: 386 QAPAPAPAPAMVSALAQAPAPVPVLA----PGPPQAVAPPAPKPTQAGEGTLSEALLQLQ 441
P AP+P LA + PVPV+A PG A A P P PT + ++ +L
Sbjct: 1608 PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAP 1667
Query: 442 FDDEDLGALLGNST---DPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPM-------LM 491
L + T PA+ L S+ L G P P T+ + L+
Sbjct: 1668 V-PSPLPSPASTQTLALAPALAPTLGGSSPSQTLS-LGTGNPQGPFPTQTLSLTPASSLV 1725
Query: 492 EYPEAITRLVTGAQRPPDP----APAPLGAPGLPNG 523
P L G P APAP AP P G
Sbjct: 1726 PTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVG 1761
Score = 50.4 bits (119), Expect = 4e-06
Identities = 59/230 (25%), Positives = 84/230 (36%), Gaps = 38/230 (16%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEF-------------------- 360
P P P + PS + +P P P P P +S T+
Sbjct: 1647 PVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGN 1706
Query: 361 PTMVFPSGQIS--QASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAV 418
P FP+ +S AS+L P P Q L AP P P +L AP P LAP P
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSL----APAPPLAPASPVGP 1762
Query: 419 APP---APKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDN--SEFQQ 473
AP P + L+ A +Q LG + + AS + S+
Sbjct: 1763 APAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASS 1822
Query: 474 LLNQG-----IPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAP 518
L+ +PV + P+ + P+ +T L +G PP A + G P
Sbjct: 1823 LVVSASGAAPLPVTMVSRLPVSKDEPDTLT-LRSGPPSPPSTATS-FGGP 1870
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/130 (31%), Positives = 56/130 (43%), Gaps = 15/130 (11%)
Query: 307 KSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFP 366
K + SP + P P I+ P +S+P PA P P +S + V
Sbjct: 1376 KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS------SPLASPVSS 1429
Query: 367 SGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA--PAPVPVLAPGPPQAV 418
+ + +S+L + P LP APA AP AP VSA A + P LAP P A
Sbjct: 1430 TVSVPLSSSLPISVPTTLP-APASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488
Query: 419 APPAPKPTQA 428
PP+ P+ A
Sbjct: 1489 GPPSLAPSGA 1498
Score = 44.7 bits (104), Expect = 2e-04
Identities = 67/263 (25%), Positives = 97/263 (36%), Gaps = 44/263 (16%)
Query: 321 PRPPPRRIAV-PSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQI--------- 370
P P P ++V PS + ++ P P P ++ PTMV +G +
Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVP------PTMVNNTGVVKIVVRQAPR 1318
Query: 371 ---SQASALAPAP-------PQVLPQAPAPAPA--PAMVSALAQAPAPVPVLAPGPPQAV 418
+ LAPAP P VL P P P A+AP P P L + V
Sbjct: 1319 DGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLV 1378
Query: 419 APPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVF---TDLASVDNSEFQQLL 475
P+P+ + + G A L + +L G ++ P + LAS +S L
Sbjct: 1379 HSPSPEVSASAPGA---APLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPL 1435
Query: 476 NQGIPVAPHTTEPMLMEYPEAI---TRLVTGAQRP-------PDPAPAPLGAPGLPNGLL 525
+ +P++ TT P P I L A P P AP APG P+
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAP 1495
Query: 526 SGDEDFSSIADMDFSALLSQISS 548
SG +S + + S SS
Sbjct: 1496 SGASPSASALTLGLATAPSLSSS 1518
Score = 44.3 bits (103), Expect = 3e-04
Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 323 PPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQ 382
P P V + S VP AP P T SL++ + PT V S + PAP
Sbjct: 1614 PSPGAAPVLASSQTPVPVMAPSSTPGT-SLASASPVPAPTPVLAP---SSTQTMLPAP-- 1667
Query: 383 VLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVA------PPAPKPTQAGEGTLSEA 436
P+P P+PA LA APA P L P P P PTQ T + +
Sbjct: 1668 ----VPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723
Query: 437 LL 438
L+
Sbjct: 1724 LV 1725
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 15/107 (14%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTIN-YDEFPTMVFPSGQISQASALAPA 379
PRP PR P+ + A++P P P +S N P + PS P
Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPS----------PP 2486
Query: 380 PPQVLPQAPAPA--PAPAMVSALAQAPAPVP--VLAPGPPQAVAPPA 422
PP +P +PA P PA A P P ++ P P + PP+
Sbjct: 2487 PPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPS 2533
Score = 43.5 bits (101), Expect = 5e-04
Identities = 46/164 (28%), Positives = 60/164 (36%), Gaps = 13/164 (7%)
Query: 316 SGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASA 375
S T PR P R VP+PAP+P P +S P V IS +
Sbjct: 2422 STTTPPRCSPAR--------ERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNP 2473
Query: 376 LAPAPPQVLPQAPAPAPAPAMVS-ALAQAPAPVPVLAPGPPQA----VAPPAPKPTQAGE 430
+ P +LP P P+ P S A PA P A PP A V P +P
Sbjct: 2474 ITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPS 2533
Query: 431 GTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQL 474
+S ++ L L + +LASV +SE L
Sbjct: 2534 VPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL 2577
Score = 40.0 bits (92), Expect = 0.006
Identities = 65/236 (27%), Positives = 83/236 (35%), Gaps = 36/236 (15%)
Query: 314 PFSGPTDPRPPPRRIAVPSRSSASVPKPA------PQPYPFTSSLSTINYDEFPTMVFPS 367
P S P P P +A P S+ SVP + P P +S P V S
Sbjct: 1410 PASSPM-PIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSAS 1468
Query: 368 GQISQASALAPAPPQVLPQAPAP---APAPAMVSA------LAQAPAPVPVLAPGPPQAV 418
G S P P V+P AP P AP+ A SA LA AP+ PG P +
Sbjct: 1469 GPALLTSVTPPLAP-VVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLL 1527
Query: 419 AP-------------PAPKPTQAGEGTLSEALLQLQFDDEDLGALL--GNSTDPAVFTDL 463
AP PA P L+ +LL +S A+ T L
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL 1587
Query: 464 ASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPG 519
A + + Q + P P P+L P A V + + P P AP PG
Sbjct: 1588 APM--AAPQTAILAPSPAPPLAPLPVLAPSPGAAP--VLASSQTPVPVMAPSSTPG 1639
Score = 36.2 bits (82), Expect = 0.080
Identities = 36/125 (28%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 316 SGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASA 375
+ P P P P+ SSAS+ PA S+ T+ P +Q A
Sbjct: 1757 ASPVGPAPAHTLTLAPASSSASLLAPA--------SVQTLTLSPAPVPTL-GPAAAQTLA 1807
Query: 376 LAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGP-----PQAV----APPAPKPT 426
LAPA Q+PA + +VSA AP PV +++ P P + PP+P T
Sbjct: 1808 LAPAS----TQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPST 1863
Query: 427 QAGEG 431
G
Sbjct: 1864 ATSFG 1868
Score = 34.7 bits (78), Expect = 0.23
Identities = 54/226 (23%), Positives = 78/226 (34%), Gaps = 37/226 (16%)
Query: 319 TDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFP---TMVFPSGQISQASA 375
T P PPPR V + + + P P ++ +N P V P ++
Sbjct: 979 TAPDPPPRPKPVKMKVNRMLQ---PVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQ 1035
Query: 376 LAPAP-PQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLS 434
P P PQVLP + + +PA + + P PVL P P Q G+L
Sbjct: 1036 PTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLP------------PLQPNSGSLP 1083
Query: 435 EALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQ---------QLLNQGIPVAPHT 485
+ L LG L G S P L + + L + + V P
Sbjct: 1084 QVL------PSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGY 1137
Query: 486 TEPMLMEYPEAITRLVTGAQRPPDPAPAP---LGAPGLPNGLLSGD 528
T P + T P P PAP + +P + L SG+
Sbjct: 1138 TFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGE 1183
>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
Length = 1047
Score = 55.5 bits (132), Expect = 1e-07
Identities = 42/115 (36%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 322 RPPPRRIAVPSRSSASVPKPA-PQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAP 380
RP P AV + S P P P P P + + + P V + S P+P
Sbjct: 658 RPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSV------TCFSLALPSP 711
Query: 381 PQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSE 435
P V +PAPAPAP+ A AQAPA AP P VA PAP T A +L +
Sbjct: 712 PAVAVASPAPAPAPSPAPARAQAPASARDPAPA-PAPVAGPAPASTSAPGDSLEQ 765
Score = 30.4 bits (67), Expect = 4.4
Identities = 29/93 (31%), Positives = 32/93 (34%), Gaps = 41/93 (44%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAP 380
P PP +A P+ P PAP P P A A APA
Sbjct: 709 PSPPAVAVASPA------PAPAPSPAP-------------------------ARAQAPAS 737
Query: 381 PQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPG 413
+ PAPAPAP PAP APG
Sbjct: 738 ----ARDPAPAPAP------VAGPAPASTSAPG 760
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/161 (28%), Positives = 66/161 (40%), Gaps = 13/161 (8%)
Query: 274 DRELSEPMEFQYLPDTDDRHRIEEKR--KRTYETFKSIMKKSPFSGPTDPRPPPRRIAVP 331
D EL +E +D+ + + R + + + S + P +GP D P P
Sbjct: 1367 DEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD---GPP 1423
Query: 332 SRSSASVPKPAPQP-YPFTSSLSTIN---YDEFPTMVFPSGQISQASALAPAPPQVLPQA 387
+A+VP P P P P +S T +E P P Q P PP PQ
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP---PQP 1480
Query: 388 PAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQA 428
P+P P +V+ +P P P+ P PP +PP P P A
Sbjct: 1481 ALPSPPP-LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAA 1520
Score = 40.0 bits (92), Expect = 0.006
Identities = 52/202 (25%), Positives = 77/202 (38%), Gaps = 24/202 (11%)
Query: 336 ASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPA 395
A + K P P P S + ++ +G L P PPQ+LP + AP+P+
Sbjct: 758 AFLQKSPPPPPPTAQSTQPTPHG----LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPS 813
Query: 396 MVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNST 455
++ P G PQ PP P P LQL+ G L +
Sbjct: 814 PSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP--------LQLEAHLRSHG-LEPAAP 864
Query: 456 DPAVFTDLASVDNSEFQQLLN--QGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDP--- 510
P + + + Q+LL + +P AP T + P + + GA R P P
Sbjct: 865 SPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG---VGPPNSEGKDPAGAYRSPSPQGT 921
Query: 511 -AP--APLGAPGLPNGLLSGDE 529
AP PL + P+ LL +E
Sbjct: 922 KAPRFVPLTSICFPDSLLQDEE 943
Score = 39.3 bits (90), Expect = 0.009
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 15/102 (14%)
Query: 320 DPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPA 379
+ +PPP P + P+P P P P +L + P +V P+ L P
Sbjct: 1454 EEKPPP----TPPPAPTPQPQPPPPPPPPQPALPSP-----PPLVAPTPSSPPPPPLPPP 1504
Query: 380 PPQVLPQAPAPAP-APAMVSALAQAPAPVPVLAPGPPQAVAP 420
PP +P P P P A A ++A + PA AP P P
Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPA-----APSPEDPELP 1541
Score = 32.0 bits (71), Expect = 1.5
Identities = 30/112 (26%), Positives = 41/112 (36%), Gaps = 13/112 (11%)
Query: 325 PRRIAVPSRSSASVPK-PAP---QPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAP 380
P PS S+ S + PA +P+P SSLS + P P+ + +
Sbjct: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSL----QDPPFSPPANGLLSPHDVLHLK 192
Query: 381 PQVLPQAPAPA-----PAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQ 427
P P P+ ++ PA P PGPP PP PTQ
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQ 244
Score = 30.4 bits (67), Expect = 4.4
Identities = 29/113 (25%), Positives = 37/113 (32%), Gaps = 42/113 (37%)
Query: 317 GPTDPRPPPRR-------IAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQ 369
GP DP PPPR +A S ++A+ + +PQ Y F
Sbjct: 230 GPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF--------------------- 268
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPA 422
S AP PP P P + + P P PP PPA
Sbjct: 269 ----SGAAPGPP------PPERALPRQDTVIKHYQRPASAQPPPPP----PPA 307
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 54.7 bits (130), Expect = 2e-07
Identities = 73/289 (25%), Positives = 116/289 (40%), Gaps = 34/289 (11%)
Query: 17 SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76
SGPY IE + R Y+ EG S G++ HP ++++GY + + L
Sbjct: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
Query: 77 ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129
D RPH H + GK +EA L + + I + + +
Sbjct: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
Query: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184
I I N E ++G+ D+ VRL F+V V PSGR L L V S+PI +
Sbjct: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL-QVASNPI-ECS 588
Query: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238
+ EL + + G + +L +D +V F WE +
Sbjct: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 647
Query: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLP 287
D+ + ++V PP+ + + +PV VS + R+ S+ F YLP
Sbjct: 648 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLP 695
>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
1 [Homo sapiens]
Length = 914
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASA----- 375
P P P+R+ + VP PAP+P P + + P P+ ++ QA
Sbjct: 269 PTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPA---PAPELQQAPEPAVGL 325
Query: 376 -LAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAV 418
APAP L AP PAP+ L APAPVP L P P V
Sbjct: 326 ESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPV 369
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP-PAPKPTQA 428
+S AL P P L PA AP+P V A A P P P APG VAP PAP+ QA
Sbjct: 261 LSPVPALKPTPELELALTPARAPSP--VPAPAPEPEPAPTPAPGSELEVAPAPAPELQQA 318
Query: 429 GE 430
E
Sbjct: 319 PE 320
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/61 (40%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 366 PSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAV---APPA 422
P +++ A AP+P P PAP PA S L APAP P L P AV + PA
Sbjct: 271 PELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPA 330
Query: 423 P 423
P
Sbjct: 331 P 331
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 379 APPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGP-PQAVAPPAP 423
A P+ L PA P P + AL A AP PV AP P P+ PAP
Sbjct: 256 AEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAP 301
>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
2 [Homo sapiens]
Length = 859
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 321 PRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASA----- 375
P P P+R+ + VP PAP+P P + + P P+ ++ QA
Sbjct: 214 PTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPA---PAPELQQAPEPAVGL 270
Query: 376 -LAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAV 418
APAP L AP PAP+ L APAPVP L P P V
Sbjct: 271 ESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPV 314
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 370 ISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAP-PAPKPTQA 428
+S AL P P L PA AP+P V A A P P P APG VAP PAP+ QA
Sbjct: 206 LSPVPALKPTPELELALTPARAPSP--VPAPAPEPEPAPTPAPGSELEVAPAPAPELQQA 263
Query: 429 GE 430
E
Sbjct: 264 PE 265
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/61 (40%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 366 PSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAV---APPA 422
P +++ A AP+P P PAP PA S L APAP P L P AV + PA
Sbjct: 216 PELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPA 275
Query: 423 P 423
P
Sbjct: 276 P 276
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 379 APPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGP-PQAVAPPAP 423
A P+ L PA P P + AL A AP PV AP P P+ PAP
Sbjct: 201 AEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAP 246
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 53.9 bits (128), Expect = 4e-07
Identities = 40/124 (32%), Positives = 50/124 (40%), Gaps = 16/124 (12%)
Query: 318 PTDPRPPPRRIAVPSRSSASVPKPAPQ----PYPFTSSLSTINYDEFPT---MVFPSGQI 370
P P PPP + S +P+P P+ P P +S S PT P+ +
Sbjct: 34 PPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEP 93
Query: 371 SQASALAPAPPQVLPQAPAPAPAPAMVS--------ALAQAPAPVPVLAPGPPQAVAP-P 421
+ A PAP AP PAP PA S AL P P P L P +AP P
Sbjct: 94 APEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEP 153
Query: 422 APKP 425
P+P
Sbjct: 154 TPEP 157
Score = 37.4 bits (85), Expect = 0.036
Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 12/74 (16%)
Query: 369 QISQASALAPAPPQVLPQAP---APAPAPAMVSALAQAPAPVPV--LAPGP-PQAVAPPA 422
Q + A +P PP P P AP PAP ++S + P P P LAPGP P+A + A
Sbjct: 15 QDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESA 74
Query: 423 ------PKPTQAGE 430
P P A E
Sbjct: 75 TELYTEPTPEPATE 88
Score = 29.3 bits (64), Expect = 9.7
Identities = 37/142 (26%), Positives = 45/142 (31%), Gaps = 32/142 (22%)
Query: 373 ASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGT 432
A+A APPQ Q PA +P P P P P PP A P P ++A
Sbjct: 6 AAAQGTAPPQDGEQ-PAESPEP-----------PPPWPPPPPPPAPPPAPPLLSEASPEP 53
Query: 433 LSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLME 492
+ E +L P + S +E P TEP
Sbjct: 54 IPEPCPELA---------------PGPCPEATSESATELYT-----EPTPEPATEPASEP 93
Query: 493 YPEAITRLVTGAQRPPDPAPAP 514
PE T P P PAP
Sbjct: 94 APEPATEPAPEPATEPAPEPAP 115
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/137 (32%), Positives = 58/137 (42%), Gaps = 18/137 (13%)
Query: 304 ETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSS--ASVPKPAPQPYPF-TSSLSTINYDEF 360
+T + I P P P PP +PS + SVP+P P P T+ +S +
Sbjct: 475 DTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPR 534
Query: 361 PTMVFPSGQISQASALAPAPP-------QVLPQAP------APAPAPAMV-SALAQAPAP 406
P M ++ S +AP PP V+P P AP P P +V +A AP
Sbjct: 535 PPMASVV-RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 593
Query: 407 VPVLAPGPPQAVAPPAP 423
PV AP P V PP P
Sbjct: 594 APVPAPAPMPPVHPPPP 610
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/137 (32%), Positives = 58/137 (42%), Gaps = 18/137 (13%)
Query: 304 ETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSS--ASVPKPAPQPYPF-TSSLSTINYDEF 360
+T + I P P P PP +PS + SVP+P P P T+ +S +
Sbjct: 540 DTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPR 599
Query: 361 PTMVFPSGQISQASALAPAPP-------QVLPQAP------APAPAPAMV-SALAQAPAP 406
P M ++ S +AP PP V+P P AP P P +V +A AP
Sbjct: 600 PPMASVV-RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 658
Query: 407 VPVLAPGPPQAVAPPAP 423
PV AP P V PP P
Sbjct: 659 APVPAPAPMPPVHPPPP 675
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,386,582
Number of Sequences: 37866
Number of extensions: 1721305
Number of successful extensions: 27003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 1099
Number of HSP's that attempted gapping in prelim test: 12722
Number of HSP's gapped (non-prelim): 8234
length of query: 548
length of database: 18,247,518
effective HSP length: 107
effective length of query: 441
effective length of database: 14,195,856
effective search space: 6260372496
effective search space used: 6260372496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.