Search of human proteins with 223468663

Search of human proteins with 223468663

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223468663 aldo-keto reductase family 1, member B10 [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   644   0.0  
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   594   e-170
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     475   e-134
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   338   3e-93
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     325   3e-89
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    313   1e-85
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     313   1e-85
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    307   9e-84
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     307   9e-84
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     303   1e-82
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    302   2e-82
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    298   6e-81
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         114   1e-25
gi|149944410 hypothetical protein LOC57587 [Homo sapiens]              32   0.96 
gi|21687139 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltran...    30   2.1  
gi|4504011 glutamate-cysteine ligase regulatory protein [Homo sa...    30   2.8  
gi|122937514 unc-13 homolog C [Homo sapiens]                           29   6.2  

>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  644 bits (1662), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
           MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ
Sbjct: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60

Query: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
           EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD
Sbjct: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP
Sbjct: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
           VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 301 VLQSSHLEDYPFNAEY 316
           VLQSSHLEDYPFNAEY
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  594 bits (1531), Expect = e-170
 Identities = 289/316 (91%), Positives = 301/316 (95%)

Query: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
           MATFVELSTKAKMPIVGLGTW+S LGKVKEAVKVAIDA YRHIDCAY Y+N+HEVGEAIQ
Sbjct: 1   MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ 60

Query: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
           EKIQEKAV REDLFIVSK+WPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK+GD
Sbjct: 61  EKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD 120

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           D FPKDDKGN I GK TFLDAWEAMEELVDEGLVKALGVSNF+HFQIE+LLNKPGLKYKP
Sbjct: 121 DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP 180

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
           VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HKKT AQVLIRFHIQRNV VIPKS+TPA IVENIQVFDFKLSDEEMATILSFNRNWRA +
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 301 VLQSSHLEDYPFNAEY 316
             + SHLED+PF+AEY
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  475 bits (1222), Expect = e-134
 Identities = 223/316 (70%), Positives = 263/316 (83%)

Query: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
           MA+ + L+  AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ
Sbjct: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
           EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G 
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           + FP D+ GN +      LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
             NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C 
Sbjct: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300

Query: 301 VLQSSHLEDYPFNAEY 316
           +L  +  +DYPF+ E+
Sbjct: 301 LLSCTSHKDYPFHEEF 316


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  338 bits (868), Expect = 3e-93
 Identities = 177/323 (54%), Positives = 220/323 (68%), Gaps = 25/323 (7%)

Query: 13  MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
           +P VGL +WK+  GKV EAVK AIDAGYRH DCAY Y NE EVG  I+ KI+E AV+RED
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 73  LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK--------SGDDL-- 122
           LFI +KLW T  ++ LV  A  K+LK LKL+YLD+YLIHWP GFK        S  +L  
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 123 ---------FPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNK 173
                     P D+    I     FLD WEAME+LV  GLVK +GVSNF+H Q+E+LLNK
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 174 PGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK 233
           PGL++KP+TNQ+ECHPYLTQ+ LI +C S+ ++VTAY PLG         E   L+++P 
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPV 237

Query: 234 IKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFN 293
           IK IA +H K+ AQ+LIRF IQRNVIVIP S+TP+ I ENIQVFDF+L+  +M  ILS N
Sbjct: 238 IKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN 297

Query: 294 RNWRACNVLQSSHLEDYPFNAEY 316
           RN R      + + +DYPF+ EY
Sbjct: 298 RNLRLAMFPITKNHKDYPFHIEY 320


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  325 bits (833), Expect = 3e-89
 Identities = 162/317 (51%), Positives = 213/317 (67%), Gaps = 5/317 (1%)

Query: 5   VELSTKAKMPIVGLGTWKSPLGKVKEA----VKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
           + LS    +PI+GLGT+  P    K A    VKVAID GYRHID AY+YQNEHEVGEAI+
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69

Query: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
           EKI E  V+RED+F   KLW T     +VR   E+TL+ L+L Y+D+Y+I  P  FK GD
Sbjct: 70  EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           +++P+D+ G  +  K+     WEAME   D GLVK+LGVSNF+  Q+E +LNKPGLK+KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRP-WAKPEDPSLLEDPKIKEIAA 239
           V+NQVECHPY TQ KL+++C    I +TAYSPLG+   P W     P LL+D  +  +  
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249

Query: 240 KHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRAC 299
           ++ KTAAQ+++RF+IQR V+VIPKS    RI EN Q+FDF L++EEM  I + N+N R  
Sbjct: 250 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 309

Query: 300 NVLQSSHLEDYPFNAEY 316
            +L      +YPF+ EY
Sbjct: 310 ELLMWRDHPEYPFHDEY 326


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  313 bits (803), Expect = 1e-85
 Identities = 153/297 (51%), Positives = 209/297 (70%), Gaps = 3/297 (1%)

Query: 2   ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           A+ V L T  KMP++GLGTWKS  G+VK AVK A+  GYRHIDCA +Y NE E+GEA++E
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 62  KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
            +   KAV RE+LF+ SKLW T      V  A  KTL DL+L YLD+YL+HWP  F+ GD
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           + FPK+  G        + + W+A+E LV +GLV+ALG+SNF+  QI+ +L+   ++  P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
              QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W  P++P LLE+P +  +A K
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297
           + ++ AQ+L+R+ +QR VI IPKS+TP+RI++NI+VFDF  S EEM  + + N+NWR
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  313 bits (803), Expect = 1e-85
 Identities = 153/297 (51%), Positives = 209/297 (70%), Gaps = 3/297 (1%)

Query: 2   ATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           A+ V L T  KMP++GLGTWKS  G+VK AVK A+  GYRHIDCA +Y NE E+GEA++E
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 62  KIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120
            +   KAV RE+LF+ SKLW T      V  A  KTL DL+L YLD+YL+HWP  F+ GD
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180
           + FPK+  G        + + W+A+E LV +GLV+ALG+SNF+  QI+ +L+   ++  P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180

Query: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240
              QVECHPYL Q +LI +C ++G+ VTAYSPLGS DR W  P++P LLE+P +  +A K
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWR 297
           + ++ AQ+L+R+ +QR VI IPKS+TP+RI++NI+VFDF  S EEM  + + N+NWR
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWR 297


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  307 bits (786), Expect = 9e-84
 Identities = 154/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           V+L+    MP++G GT+   + P  K  EAVK+AI+AG+ HID A+VY NE +VG AI+ 
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 68  KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127

Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
           + PKD+ G  +         WEAME+  D GL K++GVSNF+H  +E +LNKPGLKYKPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187

Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307

Query: 301 VLQSSHLEDYPFNAEY 316
           +   +   +YPF+ EY
Sbjct: 308 LDIFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  307 bits (786), Expect = 9e-84
 Identities = 154/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           V+L+    MP++G GT+   + P  K  EAVK+AI+AG+ HID A+VY NE +VG AI+ 
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 68  KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127

Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
           + PKD+ G  +         WEAME+  D GL K++GVSNF+H  +E +LNKPGLKYKPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187

Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307

Query: 301 VLQSSHLEDYPFNAEY 316
           +   +   +YPF+ EY
Sbjct: 308 LDIFAGPPNYPFSDEY 323


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  303 bits (777), Expect = 1e-82
 Identities = 152/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           V+L+    MP++G GT+   + P  K  EA K+AI+AG+RHID A++Y NE +VG AI+ 
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 68  KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127

Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
           + PKD+ G  +         WEA+E+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187

Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307

Query: 301 VLQSSHLEDYPFNAEY 316
           +   +   +YPF+ EY
Sbjct: 308 LDIFAGPPNYPFSDEY 323


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  302 bits (774), Expect = 2e-82
 Identities = 152/316 (48%), Positives = 207/316 (65%), Gaps = 4/316 (1%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           VEL+    MP++G GT+   + P  +  E  K+AI+AG+RHID AY+Y NE +VG AI+ 
Sbjct: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
           KI + +VKRED+F  SKLW TFF+  +V+ A E +LK L+L Y+D+YL+H+P   K G+ 
Sbjct: 68  KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127

Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
             PKD+ G  I         WE ME+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187

Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240
            NQVECHPYL Q KL+ +C SK I + A+S LG+   + W  P  P LLEDP +  +A K
Sbjct: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKK 247

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HK+T A + +R+ +QR V+V+ KS    RI ENIQVF+F+L+ E+M  +   NRN+R   
Sbjct: 248 HKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVV 307

Query: 301 VLQSSHLEDYPFNAEY 316
           +       DYPF+ EY
Sbjct: 308 MDFLMDHPDYPFSDEY 323


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  298 bits (762), Expect = 6e-81
 Identities = 150/316 (47%), Positives = 204/316 (64%), Gaps = 4/316 (1%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           V+L+    MP++G GT+   + P  K  E  K+AI+AG+RHID A++Y NE +VG AI+ 
Sbjct: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
           KI + +VKRED+F  SKLW TF    LVR A E +LK  +L Y+D+YLIH P   K G++
Sbjct: 68  KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127

Query: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
           L P D+ G  I         WEAME+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187

Query: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240
            NQVECHPY  + KL+ +C SK I + AYS LGS  D+ W  P  P LLEDP +  +A K
Sbjct: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247

Query: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ E+M  I   +RN    N
Sbjct: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFN 307

Query: 301 VLQSSHLEDYPFNAEY 316
               +   +YP++ EY
Sbjct: 308 SDSFASHPNYPYSDEY 323


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  114 bits (284), Expect = 1e-25
 Identities = 58/116 (50%), Positives = 80/116 (68%), Gaps = 3/116 (2%)

Query: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
           V+L+    MP++G GT+   + P  K  EAVK+AI+AG+ HID A+VY NE +VG AI+ 
Sbjct: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 117
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K
Sbjct: 68  KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123


>gi|149944410 hypothetical protein LOC57587 [Homo sapiens]
          Length = 532

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 21/65 (32%), Positives = 26/65 (40%)

Query: 171 LNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLE 230
           L  P  KYK      E  P  T  K   Y      TVT  SPL +PD    +  +  +  
Sbjct: 216 LLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIAN 275

Query: 231 DPKIK 235
           D K+K
Sbjct: 276 DQKVK 280


>gi|21687139 UDP-GlcNAc:betaGal
           beta-1,3-N-acetylglucosaminyltransferase 7 [Homo
           sapiens]
          Length = 401

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLK-LSYLDVYLIHWPQGFKSGD 120
           K +E+   ++ L    +L+    +   +   F  TLK++  L +LD+Y  H P  FK  D
Sbjct: 182 KQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDD 241

Query: 121 DLF 123
           D+F
Sbjct: 242 DVF 244


>gi|4504011 glutamate-cysteine ligase regulatory protein [Homo
           sapiens]
          Length = 274

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQV 185
           WE +E LV    + A+G S+    Q+E+L      + KP +NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQ--WAQVKPNSNQV 188


>gi|122937514 unc-13 homolog C [Homo sapiens]
          Length = 2214

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 8/57 (14%)

Query: 28   VKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSK---LWP 81
            VK+ V+  +D+ Y+     Y++ N HE+   + +  +++ + RED    +K    WP
Sbjct: 1542 VKDCVRACLDSTYK-----YIFDNCHELYSQLTDPSKKQDIPREDQGPTTKNLDFWP 1593


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,891,491
Number of Sequences: 37866
Number of extensions: 522326
Number of successful extensions: 1236
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1207
Number of HSP's gapped (non-prelim): 17
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.