Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 221316599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316599 chromogranin B precursor [Homo sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316599 chromogranin B precursor [Homo sapiens] 1394 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 104 3e-22
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 81 4e-15
gi|4502805 chromogranin A precursor [Homo sapiens] 75 3e-13
gi|4504487 histidine rich calcium binding protein precursor [Hom... 73 1e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 1e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 72 1e-12
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 2e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 2e-12
gi|148746195 trichohyalin [Homo sapiens] 70 5e-12
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 69 2e-11
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 68 2e-11
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 68 2e-11
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 68 3e-11
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 9e-11
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 9e-11
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 66 1e-10
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 66 1e-10
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 66 1e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 66 1e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 65 2e-10
gi|217330641 IWS1 homolog [Homo sapiens] 65 2e-10
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 65 3e-10
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 64 5e-10
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 64 5e-10
gi|44890059 involucrin [Homo sapiens] 64 5e-10
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 5e-10
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 64 5e-10
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 64 6e-10
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 64 6e-10
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 1394 bits (3608), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQV 60
MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQV
Sbjct: 1 MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQV 60
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT 120
LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT
Sbjct: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT 120
Query: 121 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGE 180
EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGE
Sbjct: 121 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGE 180
Query: 181 DSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESG 240
DSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESG
Sbjct: 181 DSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESG 240
Query: 241 EETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLP 300
EETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLP
Sbjct: 241 EETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLP 300
Query: 301 SEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWE 360
SEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWE
Sbjct: 301 SEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWE 360
Query: 361 RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHR 420
RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHR
Sbjct: 361 RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHR 420
Query: 421 GRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAP 480
GRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAP
Sbjct: 421 GRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAP 480
Query: 481 GKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRD 540
GKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRD
Sbjct: 481 GKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRD 540
Query: 541 NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ 600
NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ
Sbjct: 541 NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ 600
Query: 601 YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA 660
YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA
Sbjct: 601 YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA 660
Query: 661 AMDLELQKIAEKFSQRG 677
AMDLELQKIAEKFSQRG
Sbjct: 661 AMDLELQKIAEKFSQRG 677
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 104 bits (259), Expect = 3e-22
Identities = 117/465 (25%), Positives = 179/465 (38%), Gaps = 76/465 (16%)
Query: 65 RKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWA 124
++D +++E E E + R E H E EE+ +G K
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK------E 757
Query: 125 EGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSE 184
EG G E E EE + + E++ +E++ EEEG+ +GE E
Sbjct: 758 EGEGEEVEGERE------------KEEGERKKEERAGKEEKGEEEGDQ-GEGEEEETEGR 804
Query: 185 EKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETG 244
+ EE GE + + E K ++EE E +E+ E+ + GEE G
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEE--GEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862
Query: 245 SQ---ENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPS 301
+ E +E +G+ +E EGEE+ E ++ G + +G
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE-------EEGEGEGEEEGEGEGEEE 915
Query: 302 EEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEW-- 359
E +G +EE EE GE EEE GE G G E+ EW
Sbjct: 916 EGEGKGEEEGEEGE------GE-----------GEEEEGEGEGEDG-EGEGEEEEGEWEG 957
Query: 360 --ERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESE-EERGLEPGKG 416
E G G EE + E +EE+ G GEE E EE G E G+G
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEE------------GEGEGEEEEGEEEGEEEGEG 1005
Query: 417 RHH-RGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYG 475
G G E + E + GEG +E + + R +G +E RN
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEE--GEGEGEEEEGEEEGEEREKEGEGEENRRN--REE 1061
Query: 476 EEGAPGKWQQQGDLQDTKENREEARFQDK-----QYSSHHTAEKR 515
EE GK+Q+ G+ ++ +++ EE + K +Y H T +K+
Sbjct: 1062 EEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 100 bits (248), Expect = 6e-21
Identities = 114/477 (23%), Positives = 181/477 (37%), Gaps = 97/477 (20%)
Query: 91 DASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSE 150
+ + + RGE PGE + + A+ E+W + G +E+ + Q + ++ E
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKE---LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 151 EVKTRHSE----KSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQAS 206
+ H E + RE+EEE+EGE ++GE GE+ E+ EE ERK+
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGE-GEEVEGEREKEE---------GERKKEE 779
Query: 207 AIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQ-------------------- 246
KEE G +E+T R + +E GE G +
Sbjct: 780 RAGKEEKGEEEGDQGEGE-EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 247 -------ENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQG--- 296
E +E +G+ + +EE EEGE + E + G + +G
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Query: 297 -GSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRAS-----------EEEPEY-GE 343
G EE+G + E EE GE+ + EEE E+ GE
Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958
Query: 344 EIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGE 403
E +G + + E E G G EE + EE +E ++ E ++ G GE
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEG----EGEEEGEGEGE 1014
Query: 404 ESEE------------------ERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGH 445
E EE E G E G+ R G G E R REE+ E
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRR-----NREEEE---EEE 1066
Query: 446 HRVQENQMDKARRHPQGAWKELD--RNYLNYGEEGAPGKWQQQGDLQDTKENREEAR 500
+ QE ++ R +K++ + + YG+ K Q+ + +T+ N +E R
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKH----KTYQKKSVTNTQGNGKEQR 1119
Score = 87.4 bits (215), Expect = 4e-17
Identities = 114/493 (23%), Positives = 187/493 (37%), Gaps = 53/493 (10%)
Query: 94 EAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVK 153
EA+E + + G + +I D + +EG S A++ + + +
Sbjct: 607 EANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP------EGRGDGTCE 660
Query: 154 TRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFL-NERKQASAIKKEE 212
S +DEE E+GE KG RGE +E PGE + E + +++E
Sbjct: 661 EGSSGAEHWQDEEREKGEK-DKG-RGE-------MERPGEGEKELAEKEEWKKRDGEEQE 711
Query: 213 LVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATS 272
R + H +QE E+ E EE G +E +E +G+ + + E EE E +
Sbjct: 712 QKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE-EEKEGEGKEEGEGEEVEGEREK 770
Query: 273 EVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGE---KRDHHS 329
E +R+ R + QG E +G +E+ E V + E +R+
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEE 830
Query: 330 THYRASEEEPEYGEEIKGY--------PGVQAPEDLEWER--YRGRGSEEYRAPRPQSEE 379
EEE E GEE +G G + E+ E E G G E + EE
Sbjct: 831 EEGEGEEEEGE-GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889
Query: 380 SWDEEDKRNYPSLELDKMAHGYGEESE-----EERGLE----------PGKGRHHRGRGG 424
+ E + E ++ G GEE E EE G E G+G G G
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949
Query: 425 EPRAYFMSDTRE---EKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPG 481
E + + E E GEG E + ++ +G +E + GEE G
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE----GEEEGEG 1005
Query: 482 KWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDN 541
+ + +G+ ++ +E E + ++ E+ + GE + + + + E +
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1065
Query: 542 MNDNFLEGEEENE 554
GEEENE
Sbjct: 1066 EGKYQETGEEENE 1078
Score = 67.8 bits (164), Expect = 3e-11
Identities = 82/384 (21%), Positives = 142/384 (36%), Gaps = 58/384 (15%)
Query: 164 DEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAG 223
DEE E E + E + + E+ E E RK+ + I ++L ++E
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEV---- 636
Query: 224 HSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRH 283
S+ + G E+ P + R EEG A D+ R +
Sbjct: 637 ------------SEGKAKSVGEAEDGP-----EGRGDGTCEEGSSGAEHWQDEEREKGEK 679
Query: 284 HHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGE 343
GR +R +G +E++ + + EE G +++ + EEE GE
Sbjct: 680 DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 344 EIKGYPGVQAP-----------EDLEWERYRGRG---SEEYRAPRPQSEESWDE------ 383
E +G + E++E ER + G EE + EE D+
Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE 799
Query: 384 ------EDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREE 437
E+K +E ++ G GE EEE E G+G G G E EE
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKGEREEEE---EEGEGEEEEGEGEEEEG-----EGEE 851
Query: 438 KRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKW-QQQGDLQDTKENR 496
+ G+G +E + ++ +G +E + GEE G+ +++G+ + +E
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE--GEGEEEGEGEGEEEEGEGEGEEEGE 909
Query: 497 EEARFQDKQYSSHHTAEKRKRLGE 520
E ++ + E+ + GE
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGE 933
Score = 59.7 bits (143), Expect = 9e-09
Identities = 52/213 (24%), Positives = 88/213 (41%), Gaps = 20/213 (9%)
Query: 94 EAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVK 153
E E GE G E+ +G + + E EG G E E + + + EE
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEE---EGEGEGEE---EGEGEGEEGEGEGEEEEG 986
Query: 154 TRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEEL 213
E+ + E+E EEEGE ++GE GE EE+ GE + E + ++E
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGE-GEGEEEEE-----GEVEGEVEGEEGEGEGEEEEGE 1040
Query: 214 VARSETHAAGHSQEKTHSREKSSQESG--EETGSQENHPQESKGQPRSQEESEEGEEDAT 271
E G +E +RE+ +E G +ETG +EN Q+ +E + + +
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD------GEEYKKVSKIKGS 1094
Query: 272 SEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEK 304
+ K +T + ++ + Q +P + K
Sbjct: 1095 VKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSK 1127
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 80.9 bits (198), Expect = 4e-15
Identities = 116/553 (20%), Positives = 211/553 (38%), Gaps = 68/553 (12%)
Query: 138 QWSLYPSDSQVSEEVKT--RHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQ 195
Q ++ + ++ E+ K + EK R++E E E + + + +EK L E Q
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE----Q 326
Query: 196 NAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKG 255
L E+++ +KE R + +EK +E+ +E E+ QE E +
Sbjct: 327 EKELREQEKELREQKE---LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383
Query: 256 QPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESN 315
Q R QE+ +E+ E D+ R R + R + Q + E+K QE+
Sbjct: 384 QMREQEQKMRDQEERMWEQDE-RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 316 VSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRP 375
E+ R EE EE +Q E+ WE+ + ++ R P
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEE-----KMQKQEENMWEQ-EEKEWQQQRLPE- 495
Query: 376 QSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTR 435
Q E+ W++E ++ + E+ E+ R E G
Sbjct: 496 QKEKLWEQE--------KMQEQEEKIWEQEEKIRDQEEMWG------------------- 528
Query: 436 EEKRFLGEGHHRVQENQM----DKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQD 491
+EK+ + R QE+QM +K R Q W + +R +E W Q+ +++
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER-MEKKTQEQEKKTWDQEEKMRE 587
Query: 492 TKENRE-EARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGE 550
+ RE E + ++++ EK + E + + W+ E+ + E E
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM-WEQE--EKMQEQEEKMWEQE 644
Query: 551 E---ENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ------- 600
E E E + E+ PE WE + E ++ + K++ K Q
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 601 -YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENL 659
+++ + + + KK E + +E QE EK + + + E E+K E
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQE---EKMQEQEEEMWEQEEKMWEQE 761
Query: 660 AAMDLELQKIAEK 672
M E Q++ E+
Sbjct: 762 EKM-WEQQRLPEQ 773
Score = 72.0 bits (175), Expect = 2e-12
Identities = 119/604 (19%), Positives = 225/604 (37%), Gaps = 78/604 (12%)
Query: 69 KDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGG 128
++KE E E E + LR+ + + E + EE ++ + + + W +
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQ-----EEKMR---EQEEKMWRQ--- 374
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHL 188
ER E + + + ++ ++ + + + ++EE E + E+ E EEK +
Sbjct: 375 --EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 189 EEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQEN 248
+E + + ++ I++ E R E +EK +E++ E E+ Q+
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 249 HPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQ 308
P E K + QE+ +E EE + +K R D+ G E+K Q
Sbjct: 493 LP-EQKEKLWEQEKMQEQEEKIWEQEEKIR------------DQEEMWG---QEKKMWRQ 536
Query: 309 EESEESNVSMASLGEK-RDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGS 367
E+ E M EK RD + E + +E + Q + E ER R R
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Query: 368 ---EEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGG 424
EE R Q E+ ++E+K +E EE+ + K
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKM---------------QEQEEKMWEQEEK--------- 632
Query: 425 EPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHP---QGAWKELDRNYLNYGEEGAPG 481
+EEK + E QE +M + +R P + W+ +E
Sbjct: 633 -------MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 482 KWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDN 541
W+Q+ + T+E ++ Q+K E+ K++ E + + E+
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 542 MNDNFLEGEE---ENELTLNEKNFFPEYNYDWWEKKPFSEDVN-WGYEKRNLARVPKL-- 595
+ E EE E E + E+ PE WE + E W E++ + K+
Sbjct: 746 QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805
Query: 596 ---DLKRQYDRVAQLDQLL--HYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTE 650
++ Q +++ ++ + K + + EE + +E EK + + + E
Sbjct: 806 QEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865
Query: 651 DEKK 654
E+K
Sbjct: 866 QEEK 869
Score = 53.5 bits (127), Expect = 6e-07
Identities = 105/541 (19%), Positives = 206/541 (38%), Gaps = 63/541 (11%)
Query: 152 VKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNER-------KQ 204
V TRH +K+ R EE + + E ++ + L++ +NA L E+ K
Sbjct: 188 VSTRH-KKADRYIEELTKERDALSLELYRNTITNEELKK----KNAELQEKLPLAESEKS 242
Query: 205 ASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESE 264
+ +EL + E Q +T++ ++ EE QE ++ + + QEE
Sbjct: 243 EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL 302
Query: 265 EGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEK 324
+E E +++ R + Q E++ Q+E E M EK
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQ------EKELREQKELREQEEQMQEQEEK 356
Query: 325 RDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEE 384
R EE+ + E+ WE+ + +E + R Q E W E+
Sbjct: 357 MWEQEEKMREQEEK------------MWRQEERLWEQEKQMREQEQKM-RDQEERMW-EQ 402
Query: 385 DKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEG 444
D+R E + E+ E+ R + + + + R E + RE ++ + E
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDK 504
++E Q +K ++ + W++ ++ +WQQQ + ++ E+ + Q++
Sbjct: 463 EETMRE-QEEKMQKQEENMWEQEEK------------EWQQQRLPEQKEKLWEQEKMQEQ 509
Query: 505 QYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEE---ENELTLNEKN 561
+ EK + E++ + W+ E+ D E EE + E + ++
Sbjct: 510 EEKIWEQEEKIRDQEEMWG--QEKKMWRQ---EKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 562 FFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFP 621
E EKK + ++ E+R R K+ + + R + K +
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 622 DFYDSEEPVSTHQEA---------ENEKDRADQTVLTEDEKKELENLAAMDLE-LQKIAE 671
++ EE + +E E E+ +Q L E ++K E+ + E +Q+ E
Sbjct: 625 KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Query: 672 K 672
K
Sbjct: 685 K 685
Score = 53.5 bits (127), Expect = 6e-07
Identities = 77/376 (20%), Positives = 143/376 (38%), Gaps = 33/376 (8%)
Query: 56 ECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGP 115
E + ++ + + D+E + T+ + + D + E E EE++
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM-- 605
Query: 116 TKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQK 175
+ EK E E+ E + ++ + ++ E+ + ++ + ++EE+ E +
Sbjct: 606 -REQEEKMQE----QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 176 GERGEDSSEEKHLEEPGETQNAFLNERKQASAIKK-EELVARSETHAAGHSQEKTHSREK 234
E+ E E + ++E + Q +Q KK +E ++ +E REK
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 235 SSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSS 294
+E E QE QE + + + QEE +E+ E +++ +
Sbjct: 721 KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR--------LPE 772
Query: 295 QGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAP 354
Q L EK QE+ E M EK R EE+ G+E K +
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR-GQEEK----MWGQ 827
Query: 355 EDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPG 414
E+ W G EE Q E+ W +E+K ++ E+ E+ RG E
Sbjct: 828 EEKMW------GQEE--KMWGQEEKMWGQEEKMEE---KMQGQEEKMREQEEKMRGQEEK 876
Query: 415 -KGRHHRGRGGEPRAY 429
+ + + RG E + Y
Sbjct: 877 MREQEEKMRGQEEKIY 892
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 74.7 bits (182), Expect = 3e-13
Identities = 103/447 (23%), Positives = 170/447 (38%), Gaps = 61/447 (13%)
Query: 1 MQPTLLLSLLGAVGLAAVNSMPVDN-RNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQ 59
M+ +L+LL G V ++PV++ N + V +CI+EV+S+ LSK S P++ EC
Sbjct: 1 MRSAAVLALLLCAG--QVTALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQEC-- 56
Query: 60 VLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKAD 119
+T R D + ++N E++ L AH+ G ED +
Sbjct: 57 -FETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHS-----GFEDELSEVLEN 110
Query: 120 TEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERG 179
AE +E +E PS V E K S+++++ E + E
Sbjct: 111 QSSQAE----LKEAVEE------PSSKDVME--KREDSKEAEKSGEATDGARPQALPEPM 158
Query: 180 EDSSEEKHLEEPG---ETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSS 236
++S E + + PG E + N AS ++ ++E + G SQ + S
Sbjct: 159 QESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLS 218
Query: 237 QESGEETGSQENHPQESKGQPRSQEESEEGEEDAT-----------SEVDKRRTRPR--H 283
E G + +E +E + + + EE+ EE T E+ K +R
Sbjct: 219 AEPGWQAKREEEEEEEEEAE--AGEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALA 276
Query: 284 HHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEE--EPEY 341
G +P E+ H Q++ EE +++ G R S EE E+
Sbjct: 277 VDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEW 336
Query: 342 GEEIKGYPGVQAPEDLEWE-RYRGRGSEE-----------------YRAPRPQSEESWDE 383
+ + Q ++L E R G+ EE +R P PQ W
Sbjct: 337 EDSKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRP 396
Query: 384 EDKRNYPSLELDKMAHGYGEESEEERG 410
+ + L GY EE +EE G
Sbjct: 397 SSREDSLEAGLPLQVRGYPEEKKEEEG 423
Score = 45.4 bits (106), Expect = 2e-04
Identities = 88/397 (22%), Positives = 138/397 (34%), Gaps = 65/397 (16%)
Query: 302 EEKGHPQEESEESNV-----SMASLGEKRDHHSTH-----YRASEEEPEYGEEIKGYPGV 351
++K H E E S V S A L E + S+ S+E + GE G
Sbjct: 93 QQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQ 152
Query: 352 QAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGL 411
PE ++ + G P EE +EE +P L + + + GL
Sbjct: 153 ALPEPMQESKAEGNNQA------PGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGL 206
Query: 412 EPGKGRHHRGRGGEPRAYFMSDTREEKRFLGE-GHHRVQENQMDKA--RRHPQGAWKELD 468
G +G EP + EE+ E G V E + HP +KE+
Sbjct: 207 SQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIR 266
Query: 469 R-----NYLNYGEEGAPGKWQ--------QQGDLQDTKENREEARFQDKQYSSHHTAEKR 515
+ L G PG + +Q Q +E E A + + E
Sbjct: 267 KGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELE 326
Query: 516 KRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKP 575
+ L + D +W ++ + LEG+EE E N D K
Sbjct: 327 QEEERLSKEWEDSKRWSKMDQLAKELTAEKRLEGQEEE-----------EDNRDSSMKLS 375
Query: 576 FSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQE 635
F +G+ R P L+R +R S E D ++ P+
Sbjct: 376 FRARA-YGF------RGPGPQLRR------------GWRPSSRE--DSLEAGLPLQVRGY 414
Query: 636 AENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
E EK + + E +ELE+L+A++ EL+K+A +
Sbjct: 415 PE-EKKEEEGSANRRPEDQELESLSAIEAELEKVAHQ 450
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 72.8 bits (177), Expect = 1e-12
Identities = 95/482 (19%), Positives = 167/482 (34%), Gaps = 51/482 (10%)
Query: 70 DKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDI----------QGPTKAD 119
D+E + + +K LL P S+ H+ G+ G GEE +G D
Sbjct: 87 DREKEDEDVSKEYGHLL--PGHRSQDHKV---GDEGVSGEEVFAEHGGQARGHRGHGSED 141
Query: 120 TEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERG 179
TE AE H D E V + H R +GE+ + G
Sbjct: 142 TEDSAEHRHHLPSHRSHSH-----QDEDEDEVVSSEHHHHILRHGHRGHDGED----DEG 192
Query: 180 EDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQES 239
E+ EE+ EE T+ R + +++E V+ H + + H + +
Sbjct: 193 EEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDD 252
Query: 240 GEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSL 299
++ ++ E + Q + E++ S+ R H D S
Sbjct: 253 DDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVST 312
Query: 300 PSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAP----- 354
+ H ++ + V S GE H H + E E++ Q P
Sbjct: 313 EYGHQAHRHQDHRKEEVEAVS-GEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHH 371
Query: 355 ----EDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERG 410
E+ E E + + +P+ +S +E+ + Y + H E +EE
Sbjct: 372 GLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVS 431
Query: 411 LEPG--KGRHHRGRGGEPRAYFMSDTREEKRFLGEGHH--------RVQENQMDKARRHP 460
E G H + E + + +E GH R +++ +K +
Sbjct: 432 AELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEED 491
Query: 461 QGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKE------NREEARFQDKQYSSHHTAEK 514
G+ +E D + GE+G + Q D +D +E N+EE +DK+ E+
Sbjct: 492 PGSHEEDDES-SEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEE 550
Query: 515 RK 516
R+
Sbjct: 551 RR 552
Score = 62.0 bits (149), Expect = 2e-09
Identities = 108/472 (22%), Positives = 167/472 (35%), Gaps = 83/472 (17%)
Query: 67 DVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQ------GPTKADT 120
D +D E E E + E + A H++ G+ +ED+ GP+
Sbjct: 186 DGEDDEGEEEEEEEEE----EEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQ 241
Query: 121 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKT---RHSEKSQREDEEEEEGENYQKGE 177
GH + D+ D VS E + RH EDE+ +G +++
Sbjct: 242 -------GHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPS 294
Query: 178 RGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQ 237
S EE ++ + + ++ + +KEE+ A S H H H +
Sbjct: 295 HRHRSHEEDDNDDD-DVSTEYGHQAHRHQDHRKEEVEAVSGEH---HHHVPDHRHQGHRD 350
Query: 238 ESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV--------------------DKR 277
E +E S E Q + + EE EE+ T + D+
Sbjct: 351 EEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEY 410
Query: 278 RTRPRHHHGRSRPDRSSQ------GGSLPSEEKGHPQEESEESNVSMASLGEKRDH---- 327
+T HHH P + G PS + H EE+ S+ E H
Sbjct: 411 KTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQ--RGSIKEMSHHPPGH 468
Query: 328 ----HSTHYRA--SEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESW 381
+H R SEEE E E+ PG +D E+ + S +
Sbjct: 469 TVVKDRSHLRKDDSEEEKEKEED----PGSHEEDDESSEQGE-------KGTHHGSRDQE 517
Query: 382 DEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMS-DTREEKRF 440
DEED+ L L++ E+ EEE E + R R G P + S + EE+
Sbjct: 518 DEEDEEEGHGLSLNQEEEEE-EDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG 576
Query: 441 LGEGHHR--VQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQ 490
L E R + N +D+ R GA E + GE+ P Q+ G+ Q
Sbjct: 577 LEEDEPRFTIIPNPLDR-REEAGGASSEEES-----GEDTGPQDAQEYGNYQ 622
Score = 38.1 bits (87), Expect = 0.027
Identities = 46/217 (21%), Positives = 79/217 (36%), Gaps = 33/217 (15%)
Query: 62 KTSRKDVKDKETTE-----------NENTKFEVRLLRDPADASEAH--ESSSRGEAGAPG 108
K+ +D +D+ TE E+ + L ++H E + G+ G+
Sbjct: 400 KSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIK 459
Query: 109 EEDIQGP----TKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQRED 164
E P K + + +E+ ++P +S E T H + Q +
Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQ--E 517
Query: 165 EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGH 224
+EE+E E + E+ EE EE E ER + A + E G
Sbjct: 518 DEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGL 577
Query: 225 SQEKTH---------SREK-----SSQESGEETGSQE 247
+++ RE+ S +ESGE+TG Q+
Sbjct: 578 EEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQD 614
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.4 bits (176), Expect = 1e-12
Identities = 85/390 (21%), Positives = 154/390 (39%), Gaps = 23/390 (5%)
Query: 86 LRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRE-RADEPQWSLYPS 144
+R+ E R + G E++ Q + + EG +E + E + +
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 145 DSQVSE-EVKTRHSEKSQREDE---EEEEGE-NYQKGERGEDSSEEKHLEEPGETQNAFL 199
+ QV E E + R E RE E E+EG+ Q+G+ E + + E+ G+ +
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR--EQEGQVREQEG 178
Query: 200 NERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRS 259
R+Q ++++E + G +E+ +E+ Q+ E+ G QE ++ + Q
Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 260 QEES-EEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSM 318
QEE ++ EE + ++ R + + R + L +E+ +E++ E M
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 319 ASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLE--WERYRGRGSEEYRAPRPQ 376
E+ R EE+ EE G Q E E WE+ +E + Q
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE-Q 357
Query: 377 SEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTRE 436
E+ +E++ ++ K ++ E+ R E G G + RE
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ-----KEQMRE 412
Query: 437 EKRFLGEGHHRVQENQMDKARRHPQGAWKE 466
++ +GE Q+ QM K H G KE
Sbjct: 413 QEEQMGE-----QKEQMRKQEEH-MGEQKE 436
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/192 (19%), Positives = 79/192 (41%), Gaps = 16/192 (8%)
Query: 65 RKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWA 124
RK + E + + E ++L+ + ++ + E EE ++ + E+
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ-- 315
Query: 125 EGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDS-- 182
E+ E + + + Q+ E+ + +K Q +EE+ GE ++ ++ E+
Sbjct: 316 ------EEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR 369
Query: 183 SEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEE 242
+E+ + + E RKQ ++K+E + G +E+ +E+ E E+
Sbjct: 370 KQEEQMRKQEEQM------RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Query: 243 TGSQENHPQESK 254
QE H E K
Sbjct: 424 MRKQEEHMGEQK 435
Score = 36.6 bits (83), Expect = 0.078
Identities = 32/162 (19%), Positives = 67/162 (41%), Gaps = 11/162 (6%)
Query: 59 QVLKTSRKDVKDKETTENENTKFEVR-LLRDPADASEAHESSSRGEAGAPGEEDIQ---- 113
Q+LK + ++++T E E E +R+ + E R + G+++ Q
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 114 ----GPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEE 169
K K E G E+ + + + + Q+ ++ + ++ Q +EE+
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396
Query: 170 GENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKE 211
GE QK + GE + + EE Q + ++++ +KE
Sbjct: 397 GE--QKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 72.4 bits (176), Expect = 1e-12
Identities = 95/436 (21%), Positives = 160/436 (36%), Gaps = 55/436 (12%)
Query: 46 SKSSAPPITPE-CRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEA 104
+KS A +PE + K K + ++ E E K + + P A + ++ A
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV-KSPEKAKSPAKEEAKSPA 596
Query: 105 GAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYP--SDSQVSEEVKTRHSEKSQR 162
A E + P K + + AE +E A P P + S EE K+ KS
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP- 655
Query: 163 EDEEEEEGENYQKGERGEDSSEEK-------HLEEPGETQNAFLNERKQASAIK---KEE 212
E EE + E + + E S EK + P + ++ E K K KEE
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 213 LVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQP---RSQEESEEGEED 269
A+S A +E+ + EK+ EE S E K + +S E +E+
Sbjct: 716 --AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Query: 270 ATSEVDKRRTR-----------PRHHHGRSRPDRSSQGGSLPSEEK-------------- 304
A S DK + P + D + +P +E+
Sbjct: 774 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833
Query: 305 --GHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERY 362
P +++EE E++ +E P+ E K P V+ P++ + E
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 363 RGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGR 422
+ ++ + P P+ E E K + E ++A +E ++ + EP K +
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK---KEPDDAKAKEPSKPAEKKEA 950
Query: 423 GGEPRAYFMSDTREEK 438
E + DT+EEK
Sbjct: 951 APEKK-----DTKEEK 961
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/479 (21%), Positives = 178/479 (37%), Gaps = 44/479 (9%)
Query: 54 TPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQ 113
T +V + K+ K++E E E + E A+ E S E A E++ +
Sbjct: 464 TQVTEEVTEEEEKEAKEEEGKEEEGGEEE------EAEGGEEETKSPPAEEAASPEKEAK 517
Query: 114 GPTKADTEKWAEGGGHSRERADEPQWSLYP--SDSQVSEEVKTRHSEKSQREDE------ 165
P K + + AE +E A P P + S EE K+ KS ++E
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577
Query: 166 ------------EEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEEL 213
EE + K S ++ + P E ++ E K + +K E
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE- 636
Query: 214 VARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESE-EGEEDATS 272
A+S T S EK S EK +S E+ S +S + +S ++E + E A S
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696
Query: 273 EVDKRRTRPRHHHGRSRPD-RSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTH 331
V + P + + +S + P +E+ E+++ A EK
Sbjct: 697 PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756
Query: 332 YRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPR----PQSEESWDEEDKR 387
+ PE K ++P D E+ + EE ++P P E++ + ++
Sbjct: 757 KTLDVKSPEAKTPAK--EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA--KAPEK 812
Query: 388 NYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHR 447
P E K E+ +E + EP K P+ D+++E+ E
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 448 VQENQMDKARRHPQGAWKEL------DRNYLNYGEEGAPGKWQQQGDLQDTKENREEAR 500
E + + A P+ + E D+ + E+ AP K + + D + KE E A+
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK-PKEKTEVAK 930
Score = 57.8 bits (138), Expect = 3e-08
Identities = 65/290 (22%), Positives = 114/290 (39%), Gaps = 20/290 (6%)
Query: 145 DSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEE---PGETQNAFLNE 201
++QV+EEV ++++ E+ +EEEG ++ E GE+ ++ EE P + + + E
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE 522
Query: 202 RKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQE 261
++ A K +++ A S EK S K +S E S E +S + +S E
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Query: 262 ES-----EEGEEDATSEVDKRRTRPRHHHGRSRPDRSS-------QGGSLPSEEKGHPQE 309
++ EE + A ++ ++ P +S + S + S EK
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642
Query: 310 ESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEE 369
+ E + A EK + S S + E K V+A E E+ + EE
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA-EAKSPEKAKSPVKEE 701
Query: 370 YRAPR----PQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGK 415
++P P EE+ E ++ E EE + E K
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK 751
Score = 44.3 bits (103), Expect = 4e-04
Identities = 48/237 (20%), Positives = 98/237 (41%), Gaps = 19/237 (8%)
Query: 129 HSRERADEPQWSLYPSDSQ-VSEEVKTRHSEKSQREDEE------EEEGENYQKGERGED 181
H + +++E + S+ + V E +T ++ ++ EE EEEG+ + GE E
Sbjct: 435 HIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEA 494
Query: 182 SSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGE 241
E+ + P + A + K+A + KEE + +E + + K+ + KS +++
Sbjct: 495 EGGEEETKSPPAEEAA--SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS 552
Query: 242 ETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPS 301
+ P E+K E EE + A + ++ P +S + S P
Sbjct: 553 PAKEEAKSPPEAK-----SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS-----PE 602
Query: 302 EEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLE 358
+ K +EE++ + + + E+ + + + EE K ++PE E
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659
Score = 42.4 bits (98), Expect = 0.001
Identities = 52/240 (21%), Positives = 91/240 (37%), Gaps = 10/240 (4%)
Query: 183 SEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEE 242
S H++ E + + + ++ + I +E+ T +EK E+ +E G E
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 243 TGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSE 302
E +E+K P EE+ E++A S V + P + + S + S
Sbjct: 491 EEEAEGGEEETKSPP--AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP-AEVKSP 547
Query: 303 EKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPE--YGEEIKGYPGVQAPEDLEWE 360
EK + E + A EK + S S E+ + EE K ++PE +
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 361 -RYRGRGSEEYRAPRPQSEESWDE---EDKRNYPSLELDKMAH-GYGEESEEERGLEPGK 415
+ + E ++P + +S E +K P+ E K E EE + E K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Score = 40.8 bits (94), Expect = 0.004
Identities = 46/227 (20%), Positives = 92/227 (40%), Gaps = 7/227 (3%)
Query: 39 EVLSNALSKSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES 98
EV S +KS P+ + + K K + K + E EV++ P A E
Sbjct: 792 EVKSPEKAKS---PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848
Query: 99 SSRGEAGAPGEEDIQGPTK-ADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHS 157
++ + + P K A K E + E+ E + +++ ++V T
Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908
Query: 158 EKSQRED--EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVA 215
E + + E+ + E + ++ D ++ K +P E + A E+K K ++
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA-APEKKDTKEEKAKKPEE 967
Query: 216 RSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEE 262
+ +T A +KT S+E S ++ + S ++SK ++ E+
Sbjct: 968 KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 72.0 bits (175), Expect = 2e-12
Identities = 105/545 (19%), Positives = 212/545 (38%), Gaps = 60/545 (11%)
Query: 137 PQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQN 196
PQ L + +E+++ ++ + +E E Q+ E EEK E + Q
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318
Query: 197 AFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQ 256
R+Q I+++E R + +EK +E+ E E+ QE E + +
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 257 PRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNV 316
R QEE +E+ E++++ H + R + EEK QE+ +E
Sbjct: 379 MRRQEEMMWEKEEKIRELEEK----MHEQEKIREQEEKR----QEEEKIREQEKRQEQEA 430
Query: 317 SMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRP- 375
M EK R E++ EE + E + E R E +R
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEE-----KIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 376 -QSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDT 434
+ EE W +++K + ++ K + E+ R E K R
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE-KIRE---------------- 528
Query: 435 REEKRFLGEGHHRVQENQ-MDKARRHPQ-GAWKELDRNYLNYGEEGAPGKWQQQGDLQDT 492
+EEK + E R QE ++ + H Q W+E R +E W+Q+ +++
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR------QEQEDKMWRQEEKIREQ 582
Query: 493 KEN--REEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGE 550
+E R+E + ++++ EK + E + +Q + ++ E
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 551 EENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQL 610
+E E + E+ E + EK E+ W E++ R + ++ Q +++ + +++
Sbjct: 643 QEQEEKMGEQE---EKMCEQEEKMQEQEETMWRQEEK--IREQEKKIREQEEKIREQEEM 697
Query: 611 LHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIA 670
+ +++ ++ EE + +E E++ E +++ E + ++ L++
Sbjct: 698 MQEQEEK-----MWEQEEKMCEQEEKMQEQE--------EKMRRQEEKMWEQEVRLRQQE 744
Query: 671 EKFSQ 675
EK +
Sbjct: 745 EKMQE 749
Score = 62.4 bits (150), Expect = 1e-09
Identities = 96/500 (19%), Positives = 187/500 (37%), Gaps = 58/500 (11%)
Query: 47 KSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGA 106
++ A + E + V + V++ E N + E ++ R E E E
Sbjct: 264 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 107 PGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQV--SEEVKTRHSEKSQRED 164
+E+ + + E E+ + ++ + ++ EE+ EK +R++
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 165 E------------EEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEE 212
E EE+ E + E+ E EE+ + E + Q +Q I+++E
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443
Query: 213 LVARSETHAAGHSQEKTHSREKSSQE----SGEETGSQENHPQESKGQPRSQEESEEGEE 268
R + +EK H +EK +E EE QE E + R +E+ E EE
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 269 DATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHH 328
+ +K + + R + EEK QEE M E+
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM---HEQEKIW 560
Query: 329 STHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRN 388
R +E+ + +E K ++ E+ W R + E+ + Q E+ W +E+K
Sbjct: 561 EEEKRQEQEDKMWRQEEK----IREQEEKVW-RQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 389 YPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRV 448
++ + E+ E+ R E M+ +EEK +GE ++
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEE-----------------MTQEQEEK--MGEQEEKM 656
Query: 449 QENQMDKARRHPQGAWKELDR-----NYLNYGEEGAPGKWQQQGDLQDTKENR---EEAR 500
E Q +K + + W++ ++ + EE K ++Q ++ +E + +E +
Sbjct: 657 CE-QEEKMQEQEETMWRQEEKIREQEKKIREQEE----KIREQEEMMQEQEEKMWEQEEK 711
Query: 501 FQDKQYSSHHTAEKRKRLGE 520
+++ EK +R E
Sbjct: 712 MCEQEEKMQEQEEKMRRQEE 731
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 10/212 (4%)
Query: 121 EKWAEGGG-HSRERADEPQWSLYPSDSQVSEEVKTRHSEKS--QREDEEEEEGENYQKGE 177
E W E H +E+ E + D +E K R E+ ++E++ E+ E Q+ E
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Query: 178 RGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQ 237
EEK E+ + Q R+Q I+++E + + + G +EK +E+ Q
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 238 ESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGG 297
E E QE +E + + R QEE +E+ E +++ Q
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-- 722
Query: 298 SLPSEEKGHPQEESE-ESNVSMASLGEKRDHH 328
EEK QEE E V + EK H
Sbjct: 723 ----EEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 53.5 bits (127), Expect = 6e-07
Identities = 67/334 (20%), Positives = 129/334 (38%), Gaps = 54/334 (16%)
Query: 58 RQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTK 117
+++ + K + ++ E E + + + R E E + E EE I+ K
Sbjct: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR---K 507
Query: 118 ADTEKWAEGGGHSRERADEPQWSLYPSDSQV-SEEVKTRHSEKSQREDEEEEEGENYQKG 176
+ + W + E+ E + + + ++ +E K R E+ RE+E+ E E +
Sbjct: 508 QEEKVWRQ-----EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 177 ERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSS 236
E+ ++ ++ +E R+Q + ++E R + +EK +E+
Sbjct: 563 EKRQEQEDKMWRQEE--------KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 237 QESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQG 296
+E E+ QE +E + + R QEE + +E+ E +++
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE---------------- 658
Query: 297 GSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPED 356
EEK QEE +M EK R EE+ EE+ +Q E+
Sbjct: 659 ----QEEKMQEQEE------TMWRQEEKIREQEKKIREQEEKIREQEEM-----MQEQEE 703
Query: 357 LEWER------YRGRGSEEYRAPRPQSEESWDEE 384
WE+ + E+ R Q E+ W++E
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 72.0 bits (175), Expect = 2e-12
Identities = 98/501 (19%), Positives = 190/501 (37%), Gaps = 62/501 (12%)
Query: 138 QWSLYPSDSQVSEEVKT--RHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQ 195
Q ++ + ++ E+ K + EK R++E E E + + + +EK L E +
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 196 NAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKG 255
E ++ ++++E + + +EK +E+ E QE +E +
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 256 QPRSQE-----------ESEE--GEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSE 302
+ R QE E EE E++ E +++ R + R + E
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 303 EKGHPQEES----EESNVSMASLGEKRDHHSTHYRASEEEP---EYGEEIKGYPGVQAPE 355
EK QEE+ EE L E+++ + E+E E E+I+ + E
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 472
Query: 356 DLEWERYRGRGSEEY-----RAPRPQSEESWDEEDK----------RNYPSLELDKMAHG 400
W + + R E+ R Q ++ WD+E++ + E KM
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 401 YGEESEEERGLEPGK---GRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKAR 457
+ EE++ E K + + R E REE+ + E ++QE Q +K R
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE-QEEKMR 591
Query: 458 RHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKEN-----------REEARFQDKQY 506
+ W++ ++ +E W+Q+ + + +E +E + Q+++
Sbjct: 592 EQEEKMWEQEEKM-----QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 507 SSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPEY 566
EK + E + +Q + E + + ++G+EE EK E
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQ----EEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 567 NYDWWEKKPF-SEDVNWGYEK 586
E+K + E+ WG E+
Sbjct: 703 KMWGQEEKMWGQEEKMWGQEE 723
Score = 68.9 bits (167), Expect = 1e-11
Identities = 110/538 (20%), Positives = 204/538 (37%), Gaps = 84/538 (15%)
Query: 151 EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKK 210
+ T E ++E+E E+ + +K E EE+ E+ G+ + R+Q +++
Sbjct: 228 QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE 287
Query: 211 EELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDA 270
+E R QEK +K +E E+ QE E + + R QEE +E+
Sbjct: 288 QEKELR--------EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 271 TSEVDKRRTRPRHHHGRSRPDRSSQGGS--LPSEEKGHPQEESEESNVSMASLGEKRDHH 328
E +K + R + R + +R + EE+ QE+ E M E+R
Sbjct: 340 LWEQEK-QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE--EERIRE 396
Query: 329 STHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRN 388
EEE +E K +Q E+ WE+ + ++ R P Q E+ W++E
Sbjct: 397 REKKMREEEETMREQEEK----MQKQEENMWEQ-EEKEWQQQRLPE-QKEKLWEQE---- 446
Query: 389 YPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRV 448
++ + E+ E+ R E G +EK+ + R
Sbjct: 447 ----KMQEQEEKIWEQEEKIRDQEEMWG-------------------QEKKMWRQEKMRE 483
Query: 449 QENQM----DKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDK 504
QE+QM +K R Q W + +R W+Q L +E E R Q K
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEER------------MWEQDERL---REKEERMREQKK 528
Query: 505 QYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFP 564
+ + K+ E +D + + M + + EE E+ ++
Sbjct: 529 MWQQEEKMREEKKTQEQEKKTWD----QEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 565 EYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFY 624
E EK E+ W E++ + K+ +++ ++ + K + +
Sbjct: 585 EQE----EKMREQEEKMWEQEEKMQEQEEKM-----WEQEEKMWEQEEEDKMQEQEEMMW 635
Query: 625 DSEEPVSTHQE---AENEKDRADQTVLTEDEKK---ELENLAAMDLELQKIAEKFSQR 676
+ EE + +E + EK R + + E E+K + E + + ++Q EK ++
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Score = 61.2 bits (147), Expect = 3e-09
Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 18/219 (8%)
Query: 132 ERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE--EEEGENYQKGERGEDSSEEKHLE 189
++ E + + + ++ EE + R EK RE+EE E+ E Q+ E EEK E
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Query: 190 EPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENH 249
+ + Q E+++ ++E++ + E +E +E+ QE E+ QE
Sbjct: 600 QEEKMQ-----EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 250 PQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQE 309
+E + + R QEE +G+E +K R + G+ R + EEK QE
Sbjct: 655 MREQEEKMREQEEKMQGQE------EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 310 E----SEESNVSMASLGEKRDH-HSTHYRASEEEPEYGE 343
E EE + EK + + E PE+ E
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 60.5 bits (145), Expect = 5e-09
Identities = 94/495 (18%), Positives = 188/495 (37%), Gaps = 75/495 (15%)
Query: 69 KDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGG 128
++KE E E E + LR+ + + E + EE ++ + + + W +
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQ-----EEKMR---EQEEKMWRQ--- 336
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHL 188
ER E + + + ++ ++ + + + ++EE E + E+ E EE+ +
Sbjct: 337 --EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 189 EEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQEN 248
E E+K R E +EK +E++ E E+ Q+
Sbjct: 395 RE---------REKKM-----------REEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 249 HPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQ 308
P E K + QE+ +E EE + +K R D+ G E+K Q
Sbjct: 435 LP-EQKEKLWEQEKMQEQEEKIWEQEEKIR------------DQEEMWG---QEKKMWRQ 478
Query: 309 EESEESNVSMASLGEK-RDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGS 367
E+ E M EK RD + E E E ++ + W+ +
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ--QEEKM 536
Query: 368 EEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPR 427
E + + Q +++WD+E+K E ++M + EEE + + +
Sbjct: 537 REEKKTQEQEKKTWDQEEKMR----EEERMREREKKMREEEEMMREQEEKMQEQE----- 587
Query: 428 AYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQG 487
RE++ + E ++QE Q +K + W++ + + + EE W+Q+
Sbjct: 588 ----EKMREQEEKMWEQEEKMQE-QEEKMWEQEEKMWEQEEEDKMQEQEE---MMWEQEE 639
Query: 488 DLQDTKEN--REEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDN 545
+Q+ +E +E + ++++ EK + E + +Q + E + +
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ----EEKMREQEE 695
Query: 546 FLEGEEENELTLNEK 560
+ G+EE EK
Sbjct: 696 KMRGQEEKMWGQEEK 710
Score = 57.4 bits (137), Expect = 4e-08
Identities = 77/392 (19%), Positives = 143/392 (36%), Gaps = 9/392 (2%)
Query: 69 KDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGG 128
+D+ E E E + + + + E E EE+ + +K E
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHL 188
E+ + Q L ++ E+ K + E+ E EE+ + G+ + +EK
Sbjct: 424 EQEEKEWQQQ-RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 189 EEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQEN 248
E+ + R Q + +E + +E+ ++K Q+ EE +E
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ--EEKMREEK 540
Query: 249 HPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQ 308
QE + + QEE EE K R + + + EEK Q
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 309 EES-EESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGS 367
EE +E M EK + E+E E+ + +Q E+ WE+
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE---KMQEQEEKMWEQEEKMRE 657
Query: 368 EEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGK-GRHHRGRGGEP 426
+E + R Q E+ +E+K ++ E+ E+ RG E G+ + G E
Sbjct: 658 QEEKM-REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
Query: 427 RAYFMSDTREEKRFLGEGHHRVQENQMDKARR 458
+ + + RE++ + + ++QE + R
Sbjct: 717 KMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 56.6 bits (135), Expect = 7e-08
Identities = 66/286 (23%), Positives = 114/286 (39%), Gaps = 25/286 (8%)
Query: 141 LYPSDSQVSE-EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFL 199
++ D ++ E E + R +K +++E+ E + Q+ E+ EEK EE
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE-------- 560
Query: 200 NERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRS 259
R++ +++EE + R + +EK +E+ E E+ QE E + +
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
Query: 260 QEES---EEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNV 316
QEE +E EE + +K + + + R + EEK QEE
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Query: 317 SMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEE-YRAPRP 375
E++ +EE +G+E K + E+ W + R EE R +
Sbjct: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEK----MWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 376 QSEESWDEEDKRNY-----PSLELDKMAHGYGEESEEERGLEPGKG 416
+ +E E ++R PS L M+H S E G E G+G
Sbjct: 737 KMQERLPEHEERCSEPCLPPSKVLCNMSH---TGSVEPAGGEAGEG 779
Score = 56.2 bits (134), Expect = 1e-07
Identities = 102/510 (20%), Positives = 191/510 (37%), Gaps = 65/510 (12%)
Query: 157 SEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVAR 216
+E+ ++++ E +E + E+ E K L+ E FL + Q + +++E
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK-FLLPQVQTNTLQEE----- 235
Query: 217 SETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDK 276
+E+ +EK ++ E+ QE +E +G+ R QEE +E E +K
Sbjct: 236 -----MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290
Query: 277 RRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASE 336
+ Q L ++K QEE M EK R E
Sbjct: 291 --------------ELREQEKELREQKKLREQEE------QMQEQEEKMWEQEEKMREQE 330
Query: 337 EEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDK---RNYPSLE 393
E+ + E+ WE+ + +E + R Q E W+++++ + E
Sbjct: 331 EK------------MWRQEERLWEQEKQMREQEQKM-RDQEERMWEQDERLREKEERMRE 377
Query: 394 LDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQM 453
+KM + EEER E R + R E +EEK E + QE +
Sbjct: 378 QEKMWEQEEKMQEEERIRE----REKKMREEEE----TMREQEEKMQKQEENMWEQEEKE 429
Query: 454 DKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAE 513
+ +R P+ K ++ + EE W+Q+ ++D +E + + K + E
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKI---WEQEEKIRDQEEMWGQ---EKKMWRQEKMRE 483
Query: 514 KRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGE----EENELTLNEKNFFPEYNYD 569
+ ++ E D Q ER ++ E E E+ ++ E+ E
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 570 WWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEP 629
EKK + ++ E+R R K+ + + R + K + ++ EE
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 630 VSTHQEAENEKDRADQTVLTEDEKKELENL 659
+ +E E++ ED+ +E E +
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.5 bits (171), Expect = 5e-12
Identities = 108/563 (19%), Positives = 215/563 (38%), Gaps = 38/563 (6%)
Query: 132 ERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEP 191
+ +E +W + + EE + QRE +EEE E +K ER E E + E+
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE--EQLRKLERQELRRERQEEEQQ 296
Query: 192 GETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSRE--KSSQESGEETGSQENH 249
+ R++ ++E+ R E QE+ ++ + +E E+ +E
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 250 PQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQE 309
+ + Q R ++E E E+ E RR + + R ++ + E+ +E
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416
Query: 310 ESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEE 369
+ + E+ H H + E+ E+ + ++ E+ E R +
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 370 YRAPRPQSEESW---DEEDKRNYPSLELDKMAHGYGE--------ESEEERGLEPGKGRH 418
R + E W +EE++R ++ E + EEER + +
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 419 HRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEG 478
R E R + EEKR E R Q + ++ R Q +E +R E
Sbjct: 537 QLRREQEERREQLLKREEEKRL--EQERREQRLKREQEERRDQLLKREEERRQQRLKRE- 593
Query: 479 APGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFER 538
+ +Q+ ++ + +E R + + E+R++L L + + + + E+
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL--LKSEEQEERRQQQLRREQ 651
Query: 539 RDNMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLK 598
++ EEE L E+ E+ + E++ E+ E R +R+PK +
Sbjct: 652 QERREQRLKREEEEERL---EQRLKREHEEERREQELAEEEQEQARE-RIKSRIPKWQWQ 707
Query: 599 RQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDE----KK 654
+ + A+ ++ +K +E QE E ++ R + + ++E ++
Sbjct: 708 LESEADARQSKVYSRPRK----------QEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 655 ELENLAAMDLELQKIAEKFSQRG 677
+ E D Q AE+ S+RG
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERG 780
Score = 68.9 bits (167), Expect = 1e-11
Identities = 130/582 (22%), Positives = 217/582 (37%), Gaps = 90/582 (15%)
Query: 151 EVKTRHSEKSQREDE----EEEEGENYQKGERGEDSSEEKHLEEP----GETQNAFLNER 202
E K R E+ Q+E+E EE E Q+ ER +E EE E + L ER
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 203 KQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHP-----------Q 251
++ ++EE + + E G +E +E Q EE QE Q
Sbjct: 1047 ER--QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 252 ESKGQPRSQEESEEGEED-ATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSE--EKGHPQ 308
E + Q R +EE ++ EE E +KRR + R + + L E EK Q
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 309 E-----------ESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDL 357
E + EE + ++R YR EEE + + + Y DL
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYR-EEEELQRQKRKQRYRDEDQRSDL 1223
Query: 358 EWE--------------RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGE 403
+W+ +GR +E++R Q E+S D+++ L+ H GE
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFR----QLEDS-QLRDRQSQQDLQ-----HLLGE 1273
Query: 404 ESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGA 463
+ E +R E + + E + +E KR +E Q+ + R +
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR---RDRKSQEEKQLLREEREEKRR 1330
Query: 464 WKELDRNY-----LNYGEEGAPGKWQQQGDLQDTKENREEARFQD--KQYSSHHTAEKRK 516
+E DR + L E P + Q+ +D K EE R Q+ +++ +R+
Sbjct: 1331 RQETDRKFREEEQLLQEREEQPLRRQE----RDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 517 RLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPE---YNYDWWEK 573
F L+ + + R + + F E E++ ++ F E E+
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 574 KPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTH 633
K E+ E+ R + L+ + +Q LH +++ +F EE
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQERE------EQQLHRQERDRKF-----LEEEQQLR 1495
Query: 634 QEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEKFSQ 675
++ + K R + E E+K LE L Q+ KF Q
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEE--EQQLHRQQRQRKFLQ 1535
Score = 68.2 bits (165), Expect = 2e-11
Identities = 106/551 (19%), Positives = 217/551 (39%), Gaps = 48/551 (8%)
Query: 117 KADTEKWAEGGGHSRER-ADEPQW---SLYPSDSQVSEEVKTRHSEKSQREDEEEEEGEN 172
+A+ E+ GH E DE Q L + EE + + E+ R +EEEE E
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE- 245
Query: 173 YQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSR 232
++K E EEK EE + Q E +Q ++++EL R E Q++
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL--RRERQEEEQQQQRLRRE 303
Query: 233 EKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDR 292
++ ++ EE Q+ +E Q R +++ E E+ E ++RR + + R
Sbjct: 304 QQLRRKQEEERREQQEERREQ--QERREQQEERREQQLRREQEERREQQLRRE-QEEERR 360
Query: 293 SSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQ 352
Q EE+ Q E+ L ++ E++ ++++ ++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 353 APEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLE 412
+ L E+ R +++ R + ++E++R++ E + H E+ER
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH------EQER--- 471
Query: 413 PGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYL 472
K + R + E R ++ EE+R + R Q+ + ++ R Q ++ +
Sbjct: 472 -RKQQLKRDQEEERRERWLKLEEEERR--EQQERREQQLRREQEERREQRLKRQEE---- 524
Query: 473 NYGEEGAPGKWQQQGDLQDTKENREE---ARFQDKQYSSHHTAEKRKRLGELFNPYYDPL 529
EE + + + L+ +E R E R ++K+ ++ KR E
Sbjct: 525 ---EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE--------- 572
Query: 530 QWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPE-YNYDWWEKKPFSEDVNWGYEKRN 588
+ + +R + L+ E+E L K E + ++ + ++
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 589 LARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVL 648
L + + + +RQ + + R K E EE + + E+E++R +Q +
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREE------EEERLEQRLKREHEEERREQELA 686
Query: 649 TEDEKKELENL 659
E++++ E +
Sbjct: 687 EEEQEQARERI 697
Score = 66.2 bits (160), Expect = 9e-11
Identities = 129/615 (20%), Positives = 219/615 (35%), Gaps = 75/615 (12%)
Query: 116 TKADTEKWAEGGGHSR----ERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGE 171
T D EK A G R +E Q P D Q+ EE R +K Q ++ E EGE
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 172 NY-QKGERGEDSSEEKHLEEPGETQNAFLN------ERKQASAIK---------KEELVA 215
+K ER E ++ EE + + E +Q + K +E+L
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR 212
Query: 216 RS--ETHAAGHSQEKTHSREKSS---QESGE------ETGSQENHPQESKGQPRSQEESE 264
R E G +++ RE+ QE E ET ++ + + +P+ Q E +
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 265 EGEED--ATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLG 322
E EE + RR R + R R Q EE+ QEE E
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 323 EKR---------DHHSTHYRASEEEP-------EYGEEIKGYPGVQAPEDLEWERYRGRG 366
E+R + R +EE EE + ++ + L E+ R
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 367 SEEYRAPRPQSEESWDEEDK-RNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGE 425
+ R + + E+ E + R L ++ EE E+ E + R E
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 426 PRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQ 485
R ++ E +R E + + ++ RR +E +R E + Q+
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 486 QGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERR-----D 540
+ Q K EE R Q + S +++ E + + + E+R +
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 541 NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ 600
D L+ EEE ++ E ++ E E+R R LKR+
Sbjct: 573 ERRDQLLKREEER----RQQRLKREQEERLEQRLKREEVERLEQEERREQR-----LKRE 623
Query: 601 YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA 660
+ QLL KS E +E Q +++R +Q + E+E++ LE
Sbjct: 624 EPEEERRQQLL----KSEE-------QEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 661 AMDLELQKIAEKFSQ 675
+ E ++ ++ ++
Sbjct: 673 KREHEEERREQELAE 687
Score = 66.2 bits (160), Expect = 9e-11
Identities = 140/636 (22%), Positives = 239/636 (37%), Gaps = 90/636 (14%)
Query: 58 RQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGE-EDIQGPT 116
+Q+ + ++ + + E E + E RL R+ HE R + A E E +
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKRE-------HEEERREQELAEEEQEQARERI 697
Query: 117 KADTEKWA----------EGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE 166
K+ KW + +SR R E Q + +E K R E + EE
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQ------RRRQEQEEKRRRRESELQWQEE 751
Query: 167 EEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQ 226
E Q+ E+ D + + EE E L+ R ++ +L A
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
Query: 227 EKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHG 286
+ +E+ ++ E + +E + Q R + + + EED E +RR
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR-------- 863
Query: 287 RSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIK 346
RS+ R Q EE+ ++ + + +L E+ + EEE + E K
Sbjct: 864 RSQEQRRDQKWRWQLEEE---RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 347 GYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESE 406
Q + E E+ + EE + R + E+ +E +R Y DK ++ E
Sbjct: 921 RRRQEQERQYREEEQLQ---QEEEQLLREEREKRRRQERERQY---RKDKKLQ---QKEE 971
Query: 407 EERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKE 466
+ G EP K R R + Y REE+ E ++E + +K RR +E
Sbjct: 972 QLLGEEPEK----RRRQEREKKY-----REEEELQQEEEQLLRE-EREKRRR------QE 1015
Query: 467 LDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYY 526
+R Y E QQ + Q +E RE+ R Q++ E++ R E
Sbjct: 1016 WERQYRKKDE-------LQQEEEQLLREEREKRRLQER--------ERQYREEEELQQEE 1060
Query: 527 DPLQWKSSHFERRDNMNDNFLEGEE---ENELTLNEKNFFPEYNYDWWEKKPFSEDVNWG 583
+ L + RR + + + EE E E L E+ PE ++ E+
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE---PEKRRRQERERQCREEEELQ 1117
Query: 584 YEKRNLARVP-----KLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAEN 638
E+ L R + +L+RQY ++ Q + E P+ +E ++E E
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQ--EEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 639 EKDRADQTVLTEDEKK--ELENLAAMDLELQKIAEK 672
+ +Q + E EK+ E E + ELQ+ K
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Score = 65.9 bits (159), Expect = 1e-10
Identities = 126/639 (19%), Positives = 258/639 (40%), Gaps = 89/639 (13%)
Query: 58 RQVLKTSRKDVKDKETTENENTKFEV-RLLRDPADASEAHESSSRGEAGAPGEEDIQGPT 116
R+ + R+ ++++ E E + E +LLR+ + E + +++ +
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 117 KADTEKWAEGGGHSRERADEPQWSLYPSDSQV--SEEVKTRHSEKSQREDEEEEEGENYQ 174
+ + EK ER + L + Q+ E+ K R + Q +EEE + + +
Sbjct: 1155 REEPEKRRR---QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Query: 175 KGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREK 234
+ R ED + + E +N A++ ++ + + E + R++
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKEN----------AVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 235 SSQESGEE-TGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRS 293
SQ+ + G Q+ +E + + Q + EE+ +++ + R DR
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK--------RRDRK 1313
Query: 294 SQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQA 353
SQ EEK +EE E EKR T + EEE + +E + P +
Sbjct: 1314 SQ------EEKQLLREERE----------EKRRRQETDRKFREEE-QLLQEREEQPLRRQ 1356
Query: 354 PEDLEWE----RYRGRG----SEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEES 405
D ++ R++ +G EE R R + E + +E+++ ++ +
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 406 EEERGLEPGKGRHHRGRGGEPRAYFMSDTR---EEKRFLGEGHHRV--QENQMDKARRHP 460
EE + R + R E + R EE++ L + HR +E Q+ + R
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 461 QGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGE 520
Q +E DR +L ++ + ++ Q+ + E +F +++ H +RK L E
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 521 LFNPYYDPLQWKSSHFERRDNMNDNFLEGE------EENELTLNEKNFFPEYNYDWWEKK 574
L+ + +RR + + F E E EE +L+ E++ ++ + + +
Sbjct: 1537 -----EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD--RKFRLEEQKVR 1589
Query: 575 PFSEDVNWGYEKRNLARVP-KLDLKRQYDRVAQLD---------QLLHYRKKSAEFPDFY 624
++ + +++ L R + L+++ DR + D Q LH +++ +F +
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE-- 1647
Query: 625 DSEEPVSTHQEAENE-------KDRADQTVLTEDEKKEL 656
EEP QE E + K R ++ +L E E+++L
Sbjct: 1648 --EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Score = 63.2 bits (152), Expect = 8e-10
Identities = 110/656 (16%), Positives = 233/656 (35%), Gaps = 51/656 (7%)
Query: 56 ECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGP 115
E +Q + R+D +E E E K E L ++ E E R EE ++
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE--EEPQRQRELQEEEEQLRKL 281
Query: 116 TKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENY-- 173
+ + + + ++R Q + + E+ + R ++ +RE +EE +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 174 -------------QKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETH 220
Q+ ER E + EE E Q + ++ +++E+ + R +
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 221 AAGHS--------QEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATS 272
+E+ RE+ + EE ++ H QE + Q +E+ E +
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 273 EVDKRRTRPRHHHGRSR---PDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHS 329
E +R + R R +R + L EE+ QE E+ E+ +
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ-----LRREQEERRE 516
Query: 330 THYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNY 389
+ EEE + ++ ++ ++ E+ R E+ + + E+++R
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 390 PSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQ 449
L+ ++ + E+E LE R R + R E+R E +
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVER-------LEQEERREQRLKREEPEEER 629
Query: 450 ENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSH 509
Q+ K+ + ++L R E+ + +++ Q K EE R ++++ +
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER-REQELAEE 688
Query: 510 HTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPEYNYD 569
+ R+R+ + L+ ++ + + EG+ + EK E
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ-EQEEKRRRRESELQ 747
Query: 570 WWE---------KKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEF 620
W E ++ D W ++ + + L + Q ++ L ++
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 621 PDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEKFSQR 676
F EE + E+++ Q + E++ + E + E + E +R
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Score = 52.4 bits (124), Expect = 1e-06
Identities = 63/314 (20%), Positives = 123/314 (39%), Gaps = 28/314 (8%)
Query: 125 EGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGED--- 181
EG R+ D + D Q+ +E + + + +R+ + EE ++ ER +
Sbjct: 1608 EGQQQLRQERDRK----FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 182 -----SSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSS 236
EE+ L + GE Q ER + ++++L + +++ +E
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 237 QESGEETGSQENHPQESKGQPRSQE--ESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSS 294
+ EE QE ++ + Q R ++ E E+ + + +R+ R R + +
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER 1783
Query: 295 QGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAP 354
+ L S+E E E+ + YR EE+ + E+
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ---------E 1834
Query: 355 EDLEWERYRGRGSEEYRA----PRPQSEESWDEEDKRNYPSLELD-KMAHGYGEESEEER 409
+ L ER R +EE A R + +E W EE+++ E + H ++ EE+R
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 410 GLEPGKGRHHRGRG 423
+ G+ + G+G
Sbjct: 1895 HRQVGEIKSQEGKG 1908
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 68.6 bits (166), Expect = 2e-11
Identities = 62/268 (23%), Positives = 119/268 (44%), Gaps = 28/268 (10%)
Query: 52 PITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEED 111
P+TPE VK K T+ + K + ++ + D S + ++ EA EED
Sbjct: 29 PVTPE-----------VKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVV--EED 75
Query: 112 IQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE---EE 168
K K E +E + + ++ + + E+ K + + + E+E+ +E
Sbjct: 76 YNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEK-KEAVAAEVKNEEEDQKEDE 134
Query: 169 EGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEK 228
E +N +KGE G++ +EK E+ E +N NE+ + + K++E + E K
Sbjct: 135 EDQNEEKGEAGKEDKDEKGEEDGKEDKNG--NEKGEDA--KEKEDGKKGEDGKGNGEDGK 190
Query: 229 THSREKSSQESGEETG-SQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGR 287
++ +E +ETG +EN + KG + +EG++ E +K R + G
Sbjct: 191 EKGEDEKEEEDRKETGDGKENEDGKEKG------DKKEGKDVKVKEDEKEREDGKEDEGG 244
Query: 288 SRPDRSSQGGSLPSEEKGHPQEESEESN 315
+ + + L EE+G ++E +E +
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
Score = 59.3 bits (142), Expect = 1e-08
Identities = 60/265 (22%), Positives = 110/265 (41%), Gaps = 24/265 (9%)
Query: 124 AEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQR-EDEEEEEGENYQKGERGEDS 182
A G G R+ L V+ EVK + + S++ + + + EN +
Sbjct: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
Query: 183 SEEKHLEEPGETQNAFLNERK--QASAIKKEELVARSE-----THAAGHSQEKTHSREKS 235
++++ + E +NA E K +A A +KE + + E T G +E + K+
Sbjct: 66 TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKN 125
Query: 236 SQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV---DKRRTRPRHHHGRSRPDR 292
+E +E +N E KG+ +++ E+GEED + +K G+ D
Sbjct: 126 EEEDQKEDEEDQN---EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGED- 181
Query: 293 SSQGGSLPSEEKGHPQEESEE--------SNVSMASLGEKRDHHSTHYRASEEEPEYGEE 344
+G +EKG ++E E+ N G+K++ + E+E E G+E
Sbjct: 182 -GKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKE 240
Query: 345 IKGYPGVQAPEDLEWERYRGRGSEE 369
+G +A ++ E + G EE
Sbjct: 241 DEGGNEEEAGKEKEDLKEEEEGKEE 265
Score = 49.7 bits (117), Expect = 9e-06
Identities = 52/235 (22%), Positives = 90/235 (38%), Gaps = 43/235 (18%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
+ AP E +V + + +D +K + E EV+ + E ++ +GEAG
Sbjct: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKE 147
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
++ EK E G + + ++ E+ K EK + E+
Sbjct: 148 DKD----------EKGEEDGKEDK------------NGNEKGEDAK----EKEDGKKGED 181
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
+G E+GED EE+ +E G+ + NE + KKE
Sbjct: 182 GKGNGEDGKEKGEDEKEEEDRKETGDGKE---NEDGKEKGDKKE------------GKDV 226
Query: 228 KTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPR 282
K EK ++ E+ G E + K + +EE + EED E D ++ P+
Sbjct: 227 KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK--EEDEIKEDDGKKEEPQ 279
Score = 36.6 bits (83), Expect = 0.078
Identities = 52/295 (17%), Positives = 114/295 (38%), Gaps = 42/295 (14%)
Query: 221 AAGHSQEKTHSREKSSQESG-------EETGSQENHPQESKGQPRSQEESEEGEEDATSE 273
AAG + + +S++ S E + + ++ K + EE+ + A +E
Sbjct: 6 AAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAE 65
Query: 274 VDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
K+ + + + ++ P+ EK + + E + GEK++ + +
Sbjct: 66 T-KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK 124
Query: 334 ASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLE 393
EE+ + EE + E+ A + +E +E+ K
Sbjct: 125 NEEEDQKEDEE-------------------DQNEEKGEAGKEDKDEKGEEDGKE------ 159
Query: 394 LDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQM 453
DK + GE+++E+ + G+ G G+ + D +EE+ G + E+
Sbjct: 160 -DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKG---EDEKEEEDRKETGDGKENEDGK 215
Query: 454 DKA-RRHPQGAWKELDRNYLNYGEEGAPGKWQQQG----DLQDTKENREEARFQD 503
+K ++ + + D G+E G ++ G DL++ +E +EE ++
Sbjct: 216 EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 68.2 bits (165), Expect = 2e-11
Identities = 75/391 (19%), Positives = 156/391 (39%), Gaps = 37/391 (9%)
Query: 57 CRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES-----SSRGEAGAPGEED 111
C+ + K+SRK ++ + ++ K+ ++ D ++S+ R + ++
Sbjct: 1056 CKLLGKSSRKR---QDCSSSDTEKYSMK--EDGCNSSDKRLKRIELRERRNLSSKRNTKE 1110
Query: 112 IQ-GPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEG 170
IQ G + +D E+ +E ++R + ++ + + + + +++ +
Sbjct: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Query: 171 ENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARS----------ETH 220
E+ + GE SS+E+ ++ T+N L+ +E +++S +
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKPV--TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1228
Query: 221 AAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD----- 275
+K E + S +E GS ++ P+E K + Q E G+E+A ++V+
Sbjct: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS 1288
Query: 276 --KRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
+ +PR+ H R + G E+K P+E E + + + S
Sbjct: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1348
Query: 334 ASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLE 393
+ E E + P ++ + E E + ++ + R + +E E+K N E
Sbjct: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408
Query: 394 LDKMAHGYGEESEEER-------GLEPGKGR 417
+K EE EEE PGKGR
Sbjct: 1409 EEKEEEEEEEEEEEEEEEDENDDSKSPGKGR 1439
Score = 60.1 bits (144), Expect = 7e-09
Identities = 64/299 (21%), Positives = 119/299 (39%), Gaps = 30/299 (10%)
Query: 44 ALSKSSAPPIT---------PECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASE 94
ALSKS P+T PE R K +++K +++ + + + + E
Sbjct: 1211 ALSKSV--PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--------EPEE 1260
Query: 95 AHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKT 154
+ + + PG+E+ + ++++ +E R R + L SD + EE KT
Sbjct: 1261 GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1320
Query: 155 RHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNE---RKQASAIKKE 211
+ E +E +G N +K + SE+ +E G ++ +E R + + KK
Sbjct: 1321 KPKE------HKEVKGRNRRKVS--SEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1372
Query: 212 ELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDAT 271
EL ++ + + +E SS E+ + +E +E + + +EE EE E D +
Sbjct: 1373 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
Query: 272 SEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHST 330
K R + R + +Q EE+ E E + + E D T
Sbjct: 1433 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPT 1491
Score = 44.7 bits (104), Expect = 3e-04
Identities = 53/219 (24%), Positives = 84/219 (38%), Gaps = 13/219 (5%)
Query: 55 PECRQVLKTSRKDVKDKETTENENTK----FEVRLLRDPADASEAHESSSRGEAGAPGE- 109
P R L + V D E+ E + TK EV+ +SE E S E+G E
Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1355
Query: 110 ---EDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE 166
ED Q P +K AE + R + + +V E+ + + S+ E+EE
Sbjct: 1356 SESEDEQRPRTRSAKK-AELEENQRSYKQKKKRRRI----KVQEDSSSENKSNSEEEEEE 1410
Query: 167 EEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQ 226
+EE E ++ E E+ E + PG+ + K + + + E
Sbjct: 1411 KEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1470
Query: 227 EKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEE 265
E+ REK + E S P +K EE++E
Sbjct: 1471 EREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1509
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 68.2 bits (165), Expect = 2e-11
Identities = 75/391 (19%), Positives = 156/391 (39%), Gaps = 37/391 (9%)
Query: 57 CRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES-----SSRGEAGAPGEED 111
C+ + K+SRK ++ + ++ K+ ++ D ++S+ R + ++
Sbjct: 1094 CKLLGKSSRKR---QDCSSSDTEKYSMK--EDGCNSSDKRLKRIELRERRNLSSKRNTKE 1148
Query: 112 IQ-GPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEG 170
IQ G + +D E+ +E ++R + ++ + + + + +++ +
Sbjct: 1149 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1208
Query: 171 ENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARS----------ETH 220
E+ + GE SS+E+ ++ T+N L+ +E +++S +
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKPV--TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1266
Query: 221 AAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD----- 275
+K E + S +E GS ++ P+E K + Q E G+E+A ++V+
Sbjct: 1267 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS 1326
Query: 276 --KRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
+ +PR+ H R + G E+K P+E E + + + S
Sbjct: 1327 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1386
Query: 334 ASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLE 393
+ E E + P ++ + E E + ++ + R + +E E+K N E
Sbjct: 1387 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1446
Query: 394 LDKMAHGYGEESEEER-------GLEPGKGR 417
+K EE EEE PGKGR
Sbjct: 1447 EEKEEEEEEEEEEEEEEEDENDDSKSPGKGR 1477
Score = 60.1 bits (144), Expect = 7e-09
Identities = 64/299 (21%), Positives = 119/299 (39%), Gaps = 30/299 (10%)
Query: 44 ALSKSSAPPIT---------PECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASE 94
ALSKS P+T PE R K +++K +++ + + + + E
Sbjct: 1249 ALSKSV--PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--------EPEE 1298
Query: 95 AHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKT 154
+ + + PG+E+ + ++++ +E R R + L SD + EE KT
Sbjct: 1299 GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1358
Query: 155 RHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNE---RKQASAIKKE 211
+ E +E +G N +K + SE+ +E G ++ +E R + + KK
Sbjct: 1359 KPKE------HKEVKGRNRRKVS--SEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1410
Query: 212 ELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDAT 271
EL ++ + + +E SS E+ + +E +E + + +EE EE E D +
Sbjct: 1411 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470
Query: 272 SEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHST 330
K R + R + +Q EE+ E E + + E D T
Sbjct: 1471 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPT 1529
Score = 44.7 bits (104), Expect = 3e-04
Identities = 53/219 (24%), Positives = 84/219 (38%), Gaps = 13/219 (5%)
Query: 55 PECRQVLKTSRKDVKDKETTENENTK----FEVRLLRDPADASEAHESSSRGEAGAPGE- 109
P R L + V D E+ E + TK EV+ +SE E S E+G E
Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1393
Query: 110 ---EDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE 166
ED Q P +K AE + R + + +V E+ + + S+ E+EE
Sbjct: 1394 SESEDEQRPRTRSAKK-AELEENQRSYKQKKKRRRI----KVQEDSSSENKSNSEEEEEE 1448
Query: 167 EEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQ 226
+EE E ++ E E+ E + PG+ + K + + + E
Sbjct: 1449 KEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1508
Query: 227 EKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEE 265
E+ REK + E S P +K EE++E
Sbjct: 1509 EREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 67.8 bits (164), Expect = 3e-11
Identities = 105/479 (21%), Positives = 168/479 (35%), Gaps = 49/479 (10%)
Query: 45 LSKSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEA 104
L+ S + PE +Q LK E E K +V D + + R
Sbjct: 34 LAHSGRSHLEPEEKQALK---------RLVEEELLKMQVDEAASREDKLDLTKKGKRPPT 84
Query: 105 GAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQR-- 162
E + +++E +E A P + P+ + V+ EV E +R
Sbjct: 85 PCSDPERKRFRFNSESESGSE--------ASSPDYFGPPAKNGVAAEVSPAKEENPRRAS 136
Query: 163 ---EDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERK---QASAIKKE--ELV 214
E+ +EE + +RGE+SSEE+ G+T+ + +++ +AS +K+ E
Sbjct: 137 KAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREES 196
Query: 215 ARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV 274
SE + +K + + E S+E + K Q + E EE EED
Sbjct: 197 EESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGD 256
Query: 275 DKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA 334
K RTR +R +RS + S G E E+ + + RD R
Sbjct: 257 WKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRK 316
Query: 335 SEEEPEY-----------GEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEE---S 380
SE+ + EE G A + R EE R S+
Sbjct: 317 SEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSEAGG 376
Query: 381 WDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRF 440
+ +++N S + + S + E G+ GR GE M R ++
Sbjct: 377 GPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGEDHPAVM---RLKRYI 433
Query: 441 LGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEA 499
G HR + + H + L G +G P G + KE REEA
Sbjct: 434 RACGAHRNYKKLLGSCCSHKE-RLSILRAELEALGMKGTP----SLGKCRALKEQREEA 487
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 66.2 bits (160), Expect = 9e-11
Identities = 75/295 (25%), Positives = 110/295 (37%), Gaps = 38/295 (12%)
Query: 65 RKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWA 124
RKD K KE + + E + HE R EE + + + +K
Sbjct: 66 RKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHR-----EEQDKARREWERQKRR 120
Query: 125 E-GGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGE 180
E HSR D L + + E K R +K QRE +E E E ++ R E
Sbjct: 121 EMAREHSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 176
Query: 181 DSSEEKHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAG 223
S+ + + E P + + RK K EE S+
Sbjct: 177 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 236
Query: 224 HSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRH 283
S+ KT S E SS ESG + +E +E + + + EESEE EE+ E ++
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET------ 290
Query: 284 HHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
G + + S Q SEE+ EE E N + + D S +EEE
Sbjct: 291 --GSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 343
Score = 57.8 bits (138), Expect = 3e-08
Identities = 77/359 (21%), Positives = 135/359 (37%), Gaps = 41/359 (11%)
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT 120
L+ R ++ + + E R D + A + + SR E +++ + +
Sbjct: 19 LRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHR 78
Query: 121 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSE---KSQREDEEEEEGENYQKGE 177
AEGG H+R + E + E + RH E K++RE E ++ E ++
Sbjct: 79 SHSAEGGKHARVKEKERE-----------HERRKRHREEQDKARREWERQKRREMAREHS 127
Query: 178 RGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQ 237
R E E+ LE E + ++K+ K+ E A E ++ + + ++ +
Sbjct: 128 RRERDRLEQ-LERKRERERKMREQQKEQREQKERERRAE-ERRKEREARREVSAHHRTMR 185
Query: 238 ESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGG 297
E + + + PR + E +G + E + R S +R +
Sbjct: 186 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 245
Query: 298 SLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDL 357
S E G EE EE E+ + + SEEE E EE + G + E
Sbjct: 246 ESSSAESGSGSEEEEEEE-------EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE-- 296
Query: 358 EWERYRGRGSEEYRAPRPQSEESWDEEDKRN------YPSLELDKMAHGYGEESEEERG 410
+ E A EE ++E++ N P D+ + G EE+EEE G
Sbjct: 297 ---------ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS-GESEEAEEEVG 345
Score = 52.0 bits (123), Expect = 2e-06
Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 61/239 (25%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
S +PP P R L RK VK+++ E + LL D D S++ +S E+ +
Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSS- 249
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
AE G S E +E + EE + SE+S+ E+EEE
Sbjct: 250 ----------------AESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEEE 283
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
EE E + G E++SE+ A + +EE+ E H
Sbjct: 284 EE-EEEETGSNSEEASEQ------------------SAEEVSEEEMSEDEERENENHLLV 324
Query: 228 KTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEG---EEDATSEVDKRRTRPRH 283
SR ++SGE S+E + +G P+S +E + A S ++ ++ P++
Sbjct: 325 VPESR--FDRDSGE---SEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 378
Score = 37.7 bits (86), Expect = 0.035
Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 9/229 (3%)
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDK 504
HHR E + +K R A E ++ +E + ++ + QD K RE R + +
Sbjct: 64 HHRKDEKRKEKRRHRSHSA--EGGKHARVKEKEREHERRKRHREEQD-KARREWERQKRR 120
Query: 505 QYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFP 564
+ + H+ +R RL +L + + E+R+ E E E E+
Sbjct: 121 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK-----ERERRAEERRKEREARR 175
Query: 565 EYN-YDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDF 623
E + + ++ +S+ V + R+ R P+ + R ++ + R ++ D
Sbjct: 176 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 235
Query: 624 YDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 236 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 284
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 66.2 bits (160), Expect = 9e-11
Identities = 75/295 (25%), Positives = 110/295 (37%), Gaps = 38/295 (12%)
Query: 65 RKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWA 124
RKD K KE + + E + HE R EE + + + +K
Sbjct: 100 RKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHR-----EEQDKARREWERQKRR 154
Query: 125 E-GGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGE 180
E HSR D L + + E K R +K QRE +E E E ++ R E
Sbjct: 155 EMAREHSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 210
Query: 181 DSSEEKHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAG 223
S+ + + E P + + RK K EE S+
Sbjct: 211 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 270
Query: 224 HSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRH 283
S+ KT S E SS ESG + +E +E + + + EESEE EE+ E ++
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET------ 324
Query: 284 HHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
G + + S Q SEE+ EE E N + + D S +EEE
Sbjct: 325 --GSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 377
Score = 57.8 bits (138), Expect = 3e-08
Identities = 77/359 (21%), Positives = 135/359 (37%), Gaps = 41/359 (11%)
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT 120
L+ R ++ + + E R D + A + + SR E +++ + +
Sbjct: 53 LRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHR 112
Query: 121 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSE---KSQREDEEEEEGENYQKGE 177
AEGG H+R + E + E + RH E K++RE E ++ E ++
Sbjct: 113 SHSAEGGKHARVKEKERE-----------HERRKRHREEQDKARREWERQKRREMAREHS 161
Query: 178 RGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQ 237
R E E+ LE E + ++K+ K+ E A E ++ + + ++ +
Sbjct: 162 RRERDRLEQ-LERKRERERKMREQQKEQREQKERERRAE-ERRKEREARREVSAHHRTMR 219
Query: 238 ESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGG 297
E + + + PR + E +G + E + R S +R +
Sbjct: 220 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 279
Query: 298 SLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDL 357
S E G EE EE E+ + + SEEE E EE + G + E
Sbjct: 280 ESSSAESGSGSEEEEEEE-------EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE-- 330
Query: 358 EWERYRGRGSEEYRAPRPQSEESWDEEDKRN------YPSLELDKMAHGYGEESEEERG 410
+ E A EE ++E++ N P D+ + G EE+EEE G
Sbjct: 331 ---------ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS-GESEEAEEEVG 379
Score = 52.0 bits (123), Expect = 2e-06
Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 61/239 (25%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
S +PP P R L RK VK+++ E + LL D D S++ +S E+ +
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSS- 283
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
AE G S E +E + EE + SE+S+ E+EEE
Sbjct: 284 ----------------AESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEEE 317
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
EE E + G E++SE+ A + +EE+ E H
Sbjct: 318 EE-EEEETGSNSEEASEQ------------------SAEEVSEEEMSEDEERENENHLLV 358
Query: 228 KTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEG---EEDATSEVDKRRTRPRH 283
SR ++SGE S+E + +G P+S +E + A S ++ ++ P++
Sbjct: 359 VPESR--FDRDSGE---SEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 412
Score = 37.7 bits (86), Expect = 0.035
Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 9/229 (3%)
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDK 504
HHR E + +K R A E ++ +E + ++ + QD K RE R + +
Sbjct: 98 HHRKDEKRKEKRRHRSHSA--EGGKHARVKEKEREHERRKRHREEQD-KARREWERQKRR 154
Query: 505 QYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFP 564
+ + H+ +R RL +L + + E+R+ E E E E+
Sbjct: 155 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK-----ERERRAEERRKEREARR 209
Query: 565 EYN-YDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDF 623
E + + ++ +S+ V + R+ R P+ + R ++ + R ++ D
Sbjct: 210 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 269
Query: 624 YDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 270 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 318
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.9 bits (159), Expect = 1e-10
Identities = 87/377 (23%), Positives = 136/377 (36%), Gaps = 42/377 (11%)
Query: 45 LSKSSAPPITPECR-----QVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESS 99
LS+ P T C + K RK K +E+ E K ++ L P + E E
Sbjct: 1175 LSREIMPVSTQACVIEPIVSIPKAGRKP-KIQESEETVEPKEDMPL---PEERKEEEEMQ 1230
Query: 100 SRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEK 159
+ E GEE+ ++ A+ EP+ +VSEE + E+
Sbjct: 1231 AEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ 1290
Query: 160 SQREDEEEEE-----GENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELV 214
+ E+ E EE E Q + D ++ HLE T+ L E+ +K+E V
Sbjct: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE---STKKKELEEQPTREDVKEEPGV 1347
Query: 215 ARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV 274
S A SREK + E S+E P S + S E+ A SE
Sbjct: 1348 QESFLDA-----NMQKSREKIKDKEETELDSEEEQP--------SHDTSVVSEQMAGSED 1394
Query: 275 DKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA 334
D H + EE H + + E + E+ H Y+
Sbjct: 1395 D---------HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQD 1445
Query: 335 SEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLEL 394
EE + ++ Y QA ED + + E+ +P S +S + R+ S +
Sbjct: 1446 CEETLAACQTLQSY--TQADEDPQMSMVEDCHASEHNSP-ISSVQSHPSQSVRSVSSPNV 1502
Query: 395 DKMAHGYGEESEEERGL 411
+ GY + S E+ L
Sbjct: 1503 PALESGYTQISPEQGSL 1519
Score = 53.1 bits (126), Expect = 8e-07
Identities = 138/653 (21%), Positives = 244/653 (37%), Gaps = 91/653 (13%)
Query: 40 VLSNALSKSSAPPIT-PECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES 98
V S LSK P + P Q + R K+++T E K LL + + A +
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQ---- 896
Query: 99 SSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRE-RADEPQWSLY----PSDSQVS---E 150
GE G E + T+++ + A S++ + D P+ L P Q+ E
Sbjct: 897 EQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
Query: 151 EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNE---RKQASA 207
+K R +E S+R EG+ E S EE+ E P + L + +++
Sbjct: 957 ALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPF 1016
Query: 208 IKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGE 267
+ + V + + H + E + E E++ S+ P + +P + + EE E
Sbjct: 1017 LHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEE 1073
Query: 268 EDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDH 327
ED + R R SS+ S EE + + + SL KRD
Sbjct: 1074 EDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDV 1133
Query: 328 HSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGR--GSEEYRAPRPQSEESWDEED 385
++ P ++ KG+P ++ + + W++ GR G + R P S ++ E
Sbjct: 1134 KNSPLEPDTSTPL--KKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIE- 1190
Query: 386 KRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGH 445
P + + K A + E E +EP + + + R+E+ +
Sbjct: 1191 ----PIVSIPK-AGRKPKIQESEETVEPKEDMP------------LPEERKEEEEMQAEA 1233
Query: 446 HRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQ 505
+E + + A A D + E P + +E E+ R ++Q
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEP----------EVEEEEEKPRVSEEQ 1283
Query: 506 YSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPE 565
S + EL P +P + + + E N +D+ + E++ L +K
Sbjct: 1284 RQSEEEQQ------ELEEP--EPEEEEDAAAETAQN-DDHDADDEDDGHLESTKKKEL-- 1332
Query: 566 YNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYD 625
E++P EDV ++ + LD Q R D K+ E D
Sbjct: 1333 ------EEQPTREDV----KEEPGVQESFLDANMQKSREKIKD------KEETEL----D 1372
Query: 626 SEEPVSTH-------QEAENEKDRADQTVLTED--EKKELENLAAMDLELQKI 669
SEE +H Q A +E D + + E+ E KE E + +L+L+ +
Sbjct: 1373 SEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Score = 38.5 bits (88), Expect = 0.021
Identities = 116/546 (21%), Positives = 186/546 (34%), Gaps = 116/546 (21%)
Query: 156 HSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVA 215
+S S+ E+EE EEGEN E +E+ LE ++ K S KE+
Sbjct: 783 NSVVSEEEEEEAEEGEN------EEPQCQERELE---------ISVGKSVSHENKEQDSY 827
Query: 216 RSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD 275
E+ S S Q ++ + P R +++E D S++
Sbjct: 828 SVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKL- 886
Query: 276 KRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRAS 335
L E PQE+ E GEK + Y S
Sbjct: 887 -----------------------LLEETSSAPQEQYGE-------CGEKSEATQEQYTES 916
Query: 336 EEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEES-------WDEEDKRN 388
EE+ EE P DL +R G E +R +S E+ E R
Sbjct: 917 EEQLVASEE---QPSQDGKPDLP-KRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRR 972
Query: 389 YPSLELDK-MAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHR 447
Y E D+ + G+ E SEEE EP R P + +K FL HR
Sbjct: 973 YS--EGDRAVLRGFSESSEEEE--EP-----ESPRSSSPPILTKPTLKRKKPFL----HR 1019
Query: 448 VQENQMDKARRHPQGAWKE--------LDRNYLNYGEEGAPGKWQQQGDLQDTKENREEA 499
++ K + H E LD + + E + + ++ + +E +E
Sbjct: 1020 --RRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077
Query: 500 RFQDKQYSSH---------HTAEKRKRLGELFNPYYD-----PLQWKSSHFERRDNMNDN 545
++Y ++ KRK E + D P+ S +RD N
Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSP 1137
Query: 546 FLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRV- 604
E + L +K W K + ++W K+ R P L R+ V
Sbjct: 1138 L---EPDTSTPLKKKK--------GWPKGKSRKPIHW---KKRPGRKPGFKLSREIMPVS 1183
Query: 605 --AQLDQLLHYRKKSAEFPDFYDSEEPVSTHQE----AENEKDRADQTVLTEDEKKELEN 658
A + + + K+ P +SEE V ++ E +++ Q E E+ E E+
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED 1243
Query: 659 LAAMDL 664
A+ ++
Sbjct: 1244 AASSEV 1249
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.9 bits (159), Expect = 1e-10
Identities = 87/377 (23%), Positives = 136/377 (36%), Gaps = 42/377 (11%)
Query: 45 LSKSSAPPITPECR-----QVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESS 99
LS+ P T C + K RK K +E+ E K ++ L P + E E
Sbjct: 1175 LSREIMPVSTQACVIEPIVSIPKAGRKP-KIQESEETVEPKEDMPL---PEERKEEEEMQ 1230
Query: 100 SRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEK 159
+ E GEE+ ++ A+ EP+ +VSEE + E+
Sbjct: 1231 AEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ 1290
Query: 160 SQREDEEEEE-----GENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELV 214
+ E+ E EE E Q + D ++ HLE T+ L E+ +K+E V
Sbjct: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE---STKKKELEEQPTREDVKEEPGV 1347
Query: 215 ARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV 274
S A SREK + E S+E P S + S E+ A SE
Sbjct: 1348 QESFLDA-----NMQKSREKIKDKEETELDSEEEQP--------SHDTSVVSEQMAGSED 1394
Query: 275 DKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA 334
D H + EE H + + E + E+ H Y+
Sbjct: 1395 D---------HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQD 1445
Query: 335 SEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLEL 394
EE + ++ Y QA ED + + E+ +P S +S + R+ S +
Sbjct: 1446 CEETLAACQTLQSY--TQADEDPQMSMVEDCHASEHNSP-ISSVQSHPSQSVRSVSSPNV 1502
Query: 395 DKMAHGYGEESEEERGL 411
+ GY + S E+ L
Sbjct: 1503 PALESGYTQISPEQGSL 1519
Score = 53.1 bits (126), Expect = 8e-07
Identities = 138/653 (21%), Positives = 244/653 (37%), Gaps = 91/653 (13%)
Query: 40 VLSNALSKSSAPPIT-PECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES 98
V S LSK P + P Q + R K+++T E K LL + + A +
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQ---- 896
Query: 99 SSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRE-RADEPQWSLY----PSDSQVS---E 150
GE G E + T+++ + A S++ + D P+ L P Q+ E
Sbjct: 897 EQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
Query: 151 EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNE---RKQASA 207
+K R +E S+R EG+ E S EE+ E P + L + +++
Sbjct: 957 ALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPF 1016
Query: 208 IKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGE 267
+ + V + + H + E + E E++ S+ P + +P + + EE E
Sbjct: 1017 LHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEE 1073
Query: 268 EDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDH 327
ED + R R SS+ S EE + + + SL KRD
Sbjct: 1074 EDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDV 1133
Query: 328 HSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGR--GSEEYRAPRPQSEESWDEED 385
++ P ++ KG+P ++ + + W++ GR G + R P S ++ E
Sbjct: 1134 KNSPLEPDTSTPL--KKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIE- 1190
Query: 386 KRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGH 445
P + + K A + E E +EP + + + R+E+ +
Sbjct: 1191 ----PIVSIPK-AGRKPKIQESEETVEPKEDMP------------LPEERKEEEEMQAEA 1233
Query: 446 HRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQ 505
+E + + A A D + E P + +E E+ R ++Q
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEP----------EVEEEEEKPRVSEEQ 1283
Query: 506 YSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPE 565
S + EL P +P + + + E N +D+ + E++ L +K
Sbjct: 1284 RQSEEEQQ------ELEEP--EPEEEEDAAAETAQN-DDHDADDEDDGHLESTKKKEL-- 1332
Query: 566 YNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYD 625
E++P EDV ++ + LD Q R D K+ E D
Sbjct: 1333 ------EEQPTREDV----KEEPGVQESFLDANMQKSREKIKD------KEETEL----D 1372
Query: 626 SEEPVSTH-------QEAENEKDRADQTVLTED--EKKELENLAAMDLELQKI 669
SEE +H Q A +E D + + E+ E KE E + +L+L+ +
Sbjct: 1373 SEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Score = 38.5 bits (88), Expect = 0.021
Identities = 116/546 (21%), Positives = 186/546 (34%), Gaps = 116/546 (21%)
Query: 156 HSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVA 215
+S S+ E+EE EEGEN E +E+ LE ++ K S KE+
Sbjct: 783 NSVVSEEEEEEAEEGEN------EEPQCQERELE---------ISVGKSVSHENKEQDSY 827
Query: 216 RSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD 275
E+ S S Q ++ + P R +++E D S++
Sbjct: 828 SVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKL- 886
Query: 276 KRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRAS 335
L E PQE+ E GEK + Y S
Sbjct: 887 -----------------------LLEETSSAPQEQYGE-------CGEKSEATQEQYTES 916
Query: 336 EEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEES-------WDEEDKRN 388
EE+ EE P DL +R G E +R +S E+ E R
Sbjct: 917 EEQLVASEE---QPSQDGKPDLP-KRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRR 972
Query: 389 YPSLELDK-MAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHR 447
Y E D+ + G+ E SEEE EP R P + +K FL HR
Sbjct: 973 YS--EGDRAVLRGFSESSEEEE--EP-----ESPRSSSPPILTKPTLKRKKPFL----HR 1019
Query: 448 VQENQMDKARRHPQGAWKE--------LDRNYLNYGEEGAPGKWQQQGDLQDTKENREEA 499
++ K + H E LD + + E + + ++ + +E +E
Sbjct: 1020 --RRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077
Query: 500 RFQDKQYSSH---------HTAEKRKRLGELFNPYYD-----PLQWKSSHFERRDNMNDN 545
++Y ++ KRK E + D P+ S +RD N
Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSP 1137
Query: 546 FLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRV- 604
E + L +K W K + ++W K+ R P L R+ V
Sbjct: 1138 L---EPDTSTPLKKKK--------GWPKGKSRKPIHW---KKRPGRKPGFKLSREIMPVS 1183
Query: 605 --AQLDQLLHYRKKSAEFPDFYDSEEPVSTHQE----AENEKDRADQTVLTEDEKKELEN 658
A + + + K+ P +SEE V ++ E +++ Q E E+ E E+
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED 1243
Query: 659 LAAMDL 664
A+ ++
Sbjct: 1244 AASSEV 1249
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 65.9 bits (159), Expect = 1e-10
Identities = 87/377 (23%), Positives = 136/377 (36%), Gaps = 42/377 (11%)
Query: 45 LSKSSAPPITPECR-----QVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESS 99
LS+ P T C + K RK K +E+ E K ++ L P + E E
Sbjct: 1175 LSREIMPVSTQACVIEPIVSIPKAGRKP-KIQESEETVEPKEDMPL---PEERKEEEEMQ 1230
Query: 100 SRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEK 159
+ E GEE+ ++ A+ EP+ +VSEE + E+
Sbjct: 1231 AEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ 1290
Query: 160 SQREDEEEEE-----GENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELV 214
+ E+ E EE E Q + D ++ HLE T+ L E+ +K+E V
Sbjct: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE---STKKKELEEQPTREDVKEEPGV 1347
Query: 215 ARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEV 274
S A SREK + E S+E P S + S E+ A SE
Sbjct: 1348 QESFLDA-----NMQKSREKIKDKEETELDSEEEQP--------SHDTSVVSEQMAGSED 1394
Query: 275 DKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA 334
D H + EE H + + E + E+ H Y+
Sbjct: 1395 D---------HEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQD 1445
Query: 335 SEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLEL 394
EE + ++ Y QA ED + + E+ +P S +S + R+ S +
Sbjct: 1446 CEETLAACQTLQSY--TQADEDPQMSMVEDCHASEHNSP-ISSVQSHPSQSVRSVSSPNV 1502
Query: 395 DKMAHGYGEESEEERGL 411
+ GY + S E+ L
Sbjct: 1503 PALESGYTQISPEQGSL 1519
Score = 53.1 bits (126), Expect = 8e-07
Identities = 138/653 (21%), Positives = 244/653 (37%), Gaps = 91/653 (13%)
Query: 40 VLSNALSKSSAPPIT-PECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES 98
V S LSK P + P Q + R K+++T E K LL + + A +
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQ---- 896
Query: 99 SSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRE-RADEPQWSLY----PSDSQVS---E 150
GE G E + T+++ + A S++ + D P+ L P Q+ E
Sbjct: 897 EQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
Query: 151 EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNE---RKQASA 207
+K R +E S+R EG+ E S EE+ E P + L + +++
Sbjct: 957 ALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPF 1016
Query: 208 IKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGE 267
+ + V + + H + E + E E++ S+ P + +P + + EE E
Sbjct: 1017 LHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMP---RLEPTFEIDEEEEE 1073
Query: 268 EDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDH 327
ED + R R SS+ S EE + + + SL KRD
Sbjct: 1074 EDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDV 1133
Query: 328 HSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGR--GSEEYRAPRPQSEESWDEED 385
++ P ++ KG+P ++ + + W++ GR G + R P S ++ E
Sbjct: 1134 KNSPLEPDTSTPL--KKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIE- 1190
Query: 386 KRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGH 445
P + + K A + E E +EP + + + R+E+ +
Sbjct: 1191 ----PIVSIPK-AGRKPKIQESEETVEPKEDMP------------LPEERKEEEEMQAEA 1233
Query: 446 HRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQ 505
+E + + A A D + E P + +E E+ R ++Q
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEP----------EVEEEEEKPRVSEEQ 1283
Query: 506 YSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPE 565
S + EL P +P + + + E N +D+ + E++ L +K
Sbjct: 1284 RQSEEEQQ------ELEEP--EPEEEEDAAAETAQN-DDHDADDEDDGHLESTKKKEL-- 1332
Query: 566 YNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYD 625
E++P EDV ++ + LD Q R D K+ E D
Sbjct: 1333 ------EEQPTREDV----KEEPGVQESFLDANMQKSREKIKD------KEETEL----D 1372
Query: 626 SEEPVSTH-------QEAENEKDRADQTVLTED--EKKELENLAAMDLELQKI 669
SEE +H Q A +E D + + E+ E KE E + +L+L+ +
Sbjct: 1373 SEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Score = 38.5 bits (88), Expect = 0.021
Identities = 116/546 (21%), Positives = 186/546 (34%), Gaps = 116/546 (21%)
Query: 156 HSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVA 215
+S S+ E+EE EEGEN E +E+ LE ++ K S KE+
Sbjct: 783 NSVVSEEEEEEAEEGEN------EEPQCQERELE---------ISVGKSVSHENKEQDSY 827
Query: 216 RSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD 275
E+ S S Q ++ + P R +++E D S++
Sbjct: 828 SVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKL- 886
Query: 276 KRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRAS 335
L E PQE+ E GEK + Y S
Sbjct: 887 -----------------------LLEETSSAPQEQYGE-------CGEKSEATQEQYTES 916
Query: 336 EEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEES-------WDEEDKRN 388
EE+ EE P DL +R G E +R +S E+ E R
Sbjct: 917 EEQLVASEE---QPSQDGKPDLP-KRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRR 972
Query: 389 YPSLELDK-MAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHR 447
Y E D+ + G+ E SEEE EP R P + +K FL HR
Sbjct: 973 YS--EGDRAVLRGFSESSEEEE--EP-----ESPRSSSPPILTKPTLKRKKPFL----HR 1019
Query: 448 VQENQMDKARRHPQGAWKE--------LDRNYLNYGEEGAPGKWQQQGDLQDTKENREEA 499
++ K + H E LD + + E + + ++ + +E +E
Sbjct: 1020 --RRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDEN 1077
Query: 500 RFQDKQYSSH---------HTAEKRKRLGELFNPYYD-----PLQWKSSHFERRDNMNDN 545
++Y ++ KRK E + D P+ S +RD N
Sbjct: 1078 ELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSP 1137
Query: 546 FLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRV- 604
E + L +K W K + ++W K+ R P L R+ V
Sbjct: 1138 L---EPDTSTPLKKKK--------GWPKGKSRKPIHW---KKRPGRKPGFKLSREIMPVS 1183
Query: 605 --AQLDQLLHYRKKSAEFPDFYDSEEPVSTHQE----AENEKDRADQTVLTEDEKKELEN 658
A + + + K+ P +SEE V ++ E +++ Q E E+ E E+
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED 1243
Query: 659 LAAMDL 664
A+ ++
Sbjct: 1244 AASSEV 1249
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 65.9 bits (159), Expect = 1e-10
Identities = 108/559 (19%), Positives = 196/559 (35%), Gaps = 97/559 (17%)
Query: 62 KTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTE 121
++SR +++++ E+ + R+ R E E SRG G+ + D +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGS--QIDSHSSNSNYHD 594
Query: 122 KWAEGGGHSRERADEPQWSLYPS----DSQVSEEVKTRHSEKSQRE-------------- 163
W R+ P+ YP D + RH E+ +R+
Sbjct: 595 SW-------ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH 647
Query: 164 ---------DEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELV 214
DE EE + +R ++ + E+ E + + ER++ +KE +
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 215 ARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESE---------- 264
R +EK RE+ + +E K + R +EE E
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Query: 265 ---EGEEDATSEVDKRRTRPR--HHHGRSRPDRSSQGGSLPSEEK---GHPQEESE---- 312
E E + E DK R R R + R DR + + + GH + +S+
Sbjct: 768 RERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYR 827
Query: 313 -ESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLE-------WERYRG 364
E + S ++R HS A + E+ + V P++ E +G
Sbjct: 828 NEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG 887
Query: 365 RGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGR------H 418
R EE R P +E R Y EL + ++ E+ LE + R H
Sbjct: 888 RWKEEDRKPE-------RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940
Query: 419 HRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEG 478
H+ E T + + ++Q+ + K + G + G+
Sbjct: 941 HQSEDRE--------TSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVF 992
Query: 479 APGKWQQQGDLQ-DTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFE 537
+P K Q++ ++ K+++ ++ D++ + K+KR P P+ K E
Sbjct: 993 SPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQ---SKKKR-----GPRTPPITTKEELVE 1044
Query: 538 RRDNMNDNFLEGEEENELT 556
+ N LE ++ E T
Sbjct: 1045 MCNGKN-GILEDSQKKEDT 1062
Score = 47.4 bits (111), Expect = 4e-05
Identities = 119/609 (19%), Positives = 212/609 (34%), Gaps = 89/609 (14%)
Query: 42 SNALSKSSAPPITPECRQVLKTSRKDVK-----------DKETTENENTKFEVRLLRDPA 90
S +L KSS P + S+KD K + + N++ K R P
Sbjct: 209 SPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPP 268
Query: 91 DASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSE 150
E + + ++ I+ T+ D + RE+ D+P+ S P+ Q
Sbjct: 269 PIPEDIALGKKYKEKYKVKDRIEEKTR-DGKDRGRDFERQREKRDKPR-STSPA-GQHHS 325
Query: 151 EVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKK 210
+ +RH S + + + +R S ++ L P + +S +K
Sbjct: 326 PISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRK 385
Query: 211 EELVARSETHAAGHSQEKTHSREKSSQ------ESGEETGSQENHPQESK-------GQP 257
+ H + ++ H E++SQ E E+T + + ++S+ Q
Sbjct: 386 QS----PPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQS 441
Query: 258 RSQEESEEGE-EDATSEVDKRRTRPRHHHGRSRPDRSS---QGGSLPSEEKGHPQEESEE 313
S++ ++ E D D R TR R SR R S + S ++E P++
Sbjct: 442 SSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRST 501
Query: 314 SNVSMASLGEKRDHHSTHYRASEEEPEYGE----------EIKGYPGVQAPEDLEWERY- 362
+ E RD H EE YG EI+ ++ ++ +R
Sbjct: 502 RDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMG 561
Query: 363 --RGR-------GSEEYRAPRPQS-------EESWD------------EEDKRNYPSLEL 394
RGR GS R + S +SW+ E D R+
Sbjct: 562 RSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSS 621
Query: 395 DKMAHGYGEESE-EERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQM 453
+ HG + + ER P H+GR E D R E+R + R E
Sbjct: 622 FERRHGERDRRDNRERDQRPSSPIRHQGRNDE----LERDERREERRVDRVDDRRDERAR 677
Query: 454 DKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAE 513
++ R + +E +R E + +++ ++ + RE+ R +++ H E
Sbjct: 678 ERDRERERDRERERERERERDREREKERELERE-RAREREREREKERDRERDRDRDHDRE 736
Query: 514 KRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENEL---TLNEKNFFPEYNYDW 570
+ + D + + E R+ + E E E E E++ E DW
Sbjct: 737 RERERER------DREKEREREREERERERERERERERERERERERARERDKERERQRDW 790
Query: 571 WEKKPFSED 579
+K +D
Sbjct: 791 EDKDKGRDD 799
Score = 31.6 bits (70), Expect = 2.5
Identities = 61/355 (17%), Positives = 120/355 (33%), Gaps = 46/355 (12%)
Query: 72 ETTENENTKFEVRLLRDPAD--------ASEAHESSSRGEAGAPGEEDIQGPTKADTEKW 123
E E + E R P D ++ ++ S + G +P + D +
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAH--RSGDDQSG 1223
Query: 124 AEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSS 183
+ HS R E SL + + S + + E S+ + ++ ++ +S
Sbjct: 1224 RKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESD 1283
Query: 184 EEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEET 243
+ H L ER + H +E+ R + Q +
Sbjct: 1284 RQVHSRSGSFDSRDRLQERDRYE-----------------HDRERERERRDTRQREWDRD 1326
Query: 244 GSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTR-----PRHHHGRSRPDRSSQGGS 298
++ ++ + R +E E E D ++D+ R R R R DR+ +
Sbjct: 1327 ADKDW--PRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDR-DRTFESSQ 1383
Query: 299 LPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA-SEEEPEYGEEIKGYPGVQAPEDL 357
+ S ++ + E E +RD ST + + ++ +++ G +
Sbjct: 1384 IESVKRCEAKLEGE----------HERDLESTSRDSLALDKERMDKDLGSVQGFEETNKS 1433
Query: 358 EWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLE 412
E G +E + S S E ELD++ G E+ E+++ E
Sbjct: 1434 ERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEE 1488
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 65.1 bits (157), Expect = 2e-10
Identities = 71/378 (18%), Positives = 131/378 (34%), Gaps = 27/378 (7%)
Query: 145 DSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQ 204
D+ + + R E+ +R ++ + E E +K ER + + + E Q ER
Sbjct: 48 DADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER-- 105
Query: 205 ASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESE 264
E R + + RE+ ++ GE ++ Q + + R E+
Sbjct: 106 ------ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
Query: 265 EGEED----ATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHP----QEESEESNV 316
E + D +E ++++ R R + + R +R Q E H + E E
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 317 SMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQ 376
+ + D R +E E E E + + D E ER R R + R + +
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 377 SEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTRE 436
++ + +R E ++ E E + R R E + D +
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 437 EKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENR 496
E+ R ++ +MD+ R G R E + ++ +E R
Sbjct: 340 ERE-----RKRKRQTEMDRERNRQTG------REGRRQAERERERERERDRQSAREREER 388
Query: 497 EEARFQDKQYSSHHTAEK 514
E R +D+Q EK
Sbjct: 389 ERDRDRDRQKERERQTEK 406
Score = 57.4 bits (137), Expect = 4e-08
Identities = 82/414 (19%), Positives = 147/414 (35%), Gaps = 46/414 (11%)
Query: 65 RKDVKDKETTENE-NTKFEVRLLRDPADASEAHESSSRG-----EAGAPGEEDIQGPTKA 118
R+ ++K TE E + K E R +D + H R E E D Q +
Sbjct: 62 RERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKER 121
Query: 119 DTEKWAEG-----GGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENY 173
+ +K E G R+R + Q + + + + ++ RE + + E
Sbjct: 122 NRQKERERETEREGERGRDRQTDGQ-----RERERQRDAEKERERQTDRERQRQTERNRQ 176
Query: 174 QKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHS------QE 227
++ ER ++ E + E E +N + + ++ E +ET + Q
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 228 KTH-SREKSS--QESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHH 284
KT REK + + + E ++ + + + R ++ ++ E T +RRT
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
Query: 285 HGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEE 344
R R + + K + E E +RD R + + E E
Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRE--TERDREKERERKRKRQTEMDRE 354
Query: 345 IKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGE- 403
G + E ER R R + A + E + D++ + +K G E
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414
Query: 404 --ESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDK 455
+ E E+ E +GR RGR E + +G R +E Q D+
Sbjct: 415 EKQREREKDRESERGR-ERGREREKQ---------------KGRERDRERQTDR 452
Score = 55.5 bits (132), Expect = 2e-07
Identities = 80/435 (18%), Positives = 155/435 (35%), Gaps = 24/435 (5%)
Query: 239 SGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGS 298
S GSQE+ + GQ + ++ E + E ++RR + + R +
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 299 LPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLE 358
+ H + + + +RD R ++E E E +G G D +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 359 WERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRH 418
ER R R +E+ R Q++ + +RN + E E +R E
Sbjct: 147 RERERQRDAEKER--ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 419 HRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEG 478
H RG E ++T E++ R + + D+ R+ + K+ +R + E
Sbjct: 205 HSERGRERERERETETETERK-------RQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 479 APGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFER 538
+ +++ D ++ R++ R T KR+R E + +
Sbjct: 258 RDKERERERDRDRDRDRRQKER-------ERQTDRKRQRRTERDRETERKRERQRERERE 310
Query: 539 RDNMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEK-RNLARVPKLDL 597
R+ E E E E E+ E + + ++ E+ R R +
Sbjct: 311 RERNRKRERERERERE---RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 598 KRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELE 657
+R+ +R + D+ ++ E D + +E + EKDR Q + ++E +
Sbjct: 368 ERERERERERDRQSAREREERE----RDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
Query: 658 NLAAMDLELQKIAEK 672
+ E + EK
Sbjct: 424 RESERGRERGREREK 438
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/257 (19%), Positives = 96/257 (37%), Gaps = 17/257 (6%)
Query: 62 KTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTE 121
+ R+ ++ET ++ + E RD + E + + E D + K + +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 122 KWAEGGGH-SRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGE 180
+ E +R+R E + + +E + + E+ ++ E + N Q G G
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
Query: 181 DSSE-EKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQ---EKTHSREKSS 236
+E E+ E + Q+A E ++ + + +T Q EK REK
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 237 Q-ESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS------- 288
+ E G E G + ++ KG+ R +E + + + P RS
Sbjct: 425 ESERGRERGRER---EKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
Query: 289 -RPDRSSQGGSLPSEEK 304
RP R + S P + K
Sbjct: 482 NRPTRGIRWKSSPEDPK 498
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 65.1 bits (157), Expect = 2e-10
Identities = 120/620 (19%), Positives = 221/620 (35%), Gaps = 47/620 (7%)
Query: 88 DPADASEAHESSSRGEAGAPGEEDIQ----GPTKADTEKWAEGGGHSRERADEPQWSLYP 143
D +D A ++G+ GE+D+ G E+ +E RE +
Sbjct: 9 DQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTD 68
Query: 144 SDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERK 203
S++ + SE + +++ + E+ ++ E SE + + + G + +
Sbjct: 69 SENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKL 128
Query: 204 QASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEES 263
S + EEL+ + + K + + +E + S K Q E
Sbjct: 129 PGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESE 188
Query: 264 EEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEE-KGHPQEESEESNVSMASLG 322
E A+ ++ +PR S Q SEE H +SE + +
Sbjct: 189 EPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS 248
Query: 323 EKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWD 382
+ ++AS+ E EE+ P + E + R + SE P+P+ +S
Sbjct: 249 DSESEDPPRHQASDSE---NEELP-KPRISDSESEDPPRNQASDSENEELPKPRVSDSES 304
Query: 383 EEDKRN--YPSLELDKMAHGYGEESEEERGLEPGKGR--------HHRGRGGEPRAYFMS 432
E ++ S D H ES+++ E KG H + + + S
Sbjct: 305 EGPQKGPASDSETEDASRHKQKPESDDDSDRE-NKGEDTEMQNDSFHSDSHMDRKKFHSS 363
Query: 433 DTREE--KRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQ---QG 487
D+ EE K+ + +E + +K + + + EE A K +
Sbjct: 364 DSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSE------DEEKASAKKSRVVSDA 417
Query: 488 DLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNM-NDNF 546
D D+ +++ ++K +S E K L + N D S +N+ D F
Sbjct: 418 DDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIF 477
Query: 547 LEG--EEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRV 604
E EEE E T + E + K+ D N+ R +D ++ +
Sbjct: 478 GESGDEEEEEFTGFNQEDLEEEKGETQVKEAEDSD-----SDDNIKRGKHMDFLSDFEMM 532
Query: 605 AQLDQLLH-YRKKSAEFPDFY-DSEEPVSTHQEAENEKDRADQTVLTEDEKKELENL--- 659
Q + + R+++ + F D+++ VS NE D+ L +K L+ L
Sbjct: 533 LQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQ-LNNQKKPALKKLTLL 591
Query: 660 --AAMDLELQKIAEKFSQRG 677
M L+ Q + E F G
Sbjct: 592 PAVVMHLKKQDLKETFIDSG 611
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 64.7 bits (156), Expect = 3e-10
Identities = 81/333 (24%), Positives = 133/333 (39%), Gaps = 42/333 (12%)
Query: 90 ADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYP------ 143
A +E + GEA P ED++ P +A+ E E E +W + P
Sbjct: 1853 APEAEGDAQEAEGEA-QPESEDVEAP-EAEGEAQPES---EDVETPEAEWEVQPESEGAE 1907
Query: 144 ---SDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLN 200
++ + E ++ + +++ EDE E EG Q+ E +E + E ++
Sbjct: 1908 APEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE 1967
Query: 201 ERKQASAIKKEELVARSET-HAAGHSQEKTHSREKSSQESGEETGSQENHPQES--KGQP 257
E Q + E L ET A G +Q ++ E E + +E P+ + QP
Sbjct: 1968 EEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQP 2027
Query: 258 RSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVS 317
+S EGEE E + ++T G ++P+ S G P E EE++E+
Sbjct: 2028 KS-----EGEEAQEVEGETQKT-----EGDAQPE--SDGVEAPEAE-----EEAQEAEGE 2070
Query: 318 MASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQS 377
+ + S A E E E E + GV+APE E E + G E AP +
Sbjct: 2071 VQEAEGEAHPESEDVDAQEAEGEAQPESE---GVEAPE-AEGEAQKAEGIE---APETEG 2123
Query: 378 EESWDEEDKRNYPSLELDKMAHGYGEESEEERG 410
E+ E + P E + G E+++ G
Sbjct: 2124 -EAQPESEGIEAPEAEGEAQPESEGVEAQDAEG 2155
Score = 46.2 bits (108), Expect = 1e-04
Identities = 59/279 (21%), Positives = 109/279 (39%), Gaps = 39/279 (13%)
Query: 71 KETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEED-IQGPTKADTEKWAEGGGH 129
+E + E+ E + + +A E + + E A E D ++ P + + AEG
Sbjct: 2013 EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQ 2072
Query: 130 SRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGE-------RGEDS 182
E P+ S+ ++E + +S+ + E EGE QK E GE
Sbjct: 2073 EAEGEAHPE-----SEDVDAQEAEGEAQPESEGVEAPEAEGEA-QKAEGIEAPETEGEAQ 2126
Query: 183 SEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEE 242
E + +E P A + ++ ++ ++ ++ + G ++ + E E
Sbjct: 2127 PESEGIEAPEAEGEA----QPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEA 2182
Query: 243 TGSQENHPQESKGQPRSQEESE-----------EGEEDATSEVDKRRTRPRHHHGRSRPD 291
++ ES+G + E E E EE+A E + T G ++P+
Sbjct: 2183 PEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET--PEAEGEAQPE 2240
Query: 292 RSSQGGSLPSEEKGHPQ-----EESEESNVSMASLGEKR 325
G E+KG PQ +SEE++ S + + E R
Sbjct: 2241 SE---GETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Score = 43.9 bits (102), Expect = 5e-04
Identities = 78/394 (19%), Positives = 135/394 (34%), Gaps = 59/394 (14%)
Query: 55 PECRQVLKTSRKDVKDKETTENENTKFE--VRLLRDPADASEAHESSSRGEAGAPGEEDI 112
PE V + + ++ + E E K E + D +A EA E + E E
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077
Query: 113 QGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE------ 166
P D + E G ++ ++ + ++Q +E ++ +E + + E
Sbjct: 2078 AHPESEDVDA-QEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPE 2136
Query: 167 -EEEGENYQKGERGEDSSEEKHLEEPG-ETQNAFLNERKQASAIKKEELVARSETHAAG- 223
E E + +G +D+ E E G E Q A + + ++ E ++ + G
Sbjct: 2137 AEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGI 2196
Query: 224 -------------HSQEKTHSREKSSQE-SGEETGSQENHPQ---------ESKGQPR-- 258
E + E++ E G ET E Q E KG P+
Sbjct: 2197 EAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVS 2256
Query: 259 -SQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVS 317
+SEE E ++ + R T P S GG P + G S S
Sbjct: 2257 LGDGQSEEASESSSPVPEDRPTPP-----------PSPGGDTPHQRPGSQTGPSSSRASS 2305
Query: 318 MASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEE----YRAP 373
+ +K D + H P+ + G P + + EE R P
Sbjct: 2306 WGNCWQK-DSENDHVLGDTRSPD--AKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTP 2362
Query: 374 RPQSEESWDEEDKRNYPSL---ELDKMAHGYGEE 404
+ E +D ++ + SL E A G+G++
Sbjct: 2363 EQGASEGYDLQEDQALGSLAPTEAVGRADGFGQD 2396
Score = 38.9 bits (89), Expect = 0.016
Identities = 51/236 (21%), Positives = 84/236 (35%), Gaps = 36/236 (15%)
Query: 64 SRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKW 123
+ +D ++++ E + +L + E + G G +E+ + TE+
Sbjct: 1271 TNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330
Query: 124 AEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSS 183
+ G E E E + + E++Q E+ EE GE Q+
Sbjct: 1331 LQEEGVQLEETKE-------------TEGEGQQEEEAQLEEIEETGGEGLQE-------- 1369
Query: 184 EEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEET 243
E LEE E L +K+E L + H +E S S +
Sbjct: 1370 EGVQLEEVKEGPEGGLQGEALEEGLKEEGL----------PEEGSVHGQELSEASSPDGK 1419
Query: 244 GSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSS-QGGS 298
GSQE+ P + + R+ +E + T E T P H + P S Q GS
Sbjct: 1420 GSQEDDPVQEEEAGRASASAEPCPAEGTEE----PTEPPSHLSETDPSASERQSGS 1471
Score = 38.1 bits (87), Expect = 0.027
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 27/217 (12%)
Query: 149 SEEVKTRHSEKSQRED--EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQAS 206
SEE + + + E+ +EE + E ++G GE EE E +T+ E Q
Sbjct: 1280 SEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLE 1339
Query: 207 AIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEG 266
K+ E G Q++ E++ E EETG + QE Q +E EG
Sbjct: 1340 ETKETE----------GEGQQE----EEAQLEEIEETGGE--GLQEEGVQLEEVKEGPEG 1383
Query: 267 --EEDATSEVDKRRTRPRHH--HGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLG 322
+ +A E K P HG+ + SS G E+ +EE+ ++ S
Sbjct: 1384 GLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCP 1443
Query: 323 EKRDHHSTH--YRASEEEPEYGEEIKG---YPGVQAP 354
+ T SE +P E G PG++ P
Sbjct: 1444 AEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKP 1480
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 63.9 bits (154), Expect = 5e-10
Identities = 61/230 (26%), Positives = 89/230 (38%), Gaps = 32/230 (13%)
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGEDSSEE 185
HSR D L + + E K R +K QRE +E E E ++ R E S+
Sbjct: 148 HSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 203
Query: 186 KHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEK 228
+ + E P + + RK K EE S+ S+ K
Sbjct: 204 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERK 263
Query: 229 THSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS 288
T S E SS ESG + +E +E + + + EESEE EE+ E ++ G +
Sbjct: 264 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET--------GSN 315
Query: 289 RPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
+ S Q SEE+ EE E N + + D S +EEE
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 365
Score = 59.3 bits (142), Expect = 1e-08
Identities = 76/389 (19%), Positives = 145/389 (37%), Gaps = 70/389 (17%)
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEA----------GAP--- 107
+KT + +++K+ + + K E++ L++ D +S GE +P
Sbjct: 10 VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR 69
Query: 108 -------GEED----IQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRH 156
GEED I+ P + ++ H ++ + +W VK R
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVH---HRKDEKRKEKWK--------HARVKERE 118
Query: 157 SEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVAR 216
E+ +R EE+++ + ++ + + E H + +R++ +++++ R
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMARE-HSRRERDRLEQLERKRERERKMREQQKEQR 177
Query: 217 SETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQ---------PRSQEESEEGE 267
+ ++E+ RE + S +E++ + K PR + E +G
Sbjct: 178 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 237
Query: 268 EDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDH 327
+ E + R S +R + S E G EE EE E+ +
Sbjct: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE-------EEEEE 290
Query: 328 HSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKR 387
+ SEEE E EE + G + E + E A EE ++E++
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEE-----------ASEQSAEEVSEEEMSEDEERE 339
Query: 388 N------YPSLELDKMAHGYGEESEEERG 410
N P D+ + G EE+EEE G
Sbjct: 340 NENHLLVVPESRFDRDS-GESEEAEEEVG 367
Score = 51.2 bits (121), Expect = 3e-06
Identities = 56/206 (27%), Positives = 84/206 (40%), Gaps = 51/206 (24%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
S +PP P R L RK VK+++ E + LL D D S++ +S E+ +
Sbjct: 220 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSS- 271
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
AE G S E +E + EE + SE+S+ E+EEE
Sbjct: 272 ----------------AESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEEE 305
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
EE E + G E++SE+ EE E + + ER+ +E H +
Sbjct: 306 EE-EEEETGSNSEEASEQS-AEEVSEEEMSEDEERE-------------NENHLLVVPES 350
Query: 228 KTHSREKSSQESGEETGSQENHPQES 253
+ S+E+ EE G E PQ S
Sbjct: 351 RFDRDSGESEEAEEEVG--EGTPQSS 374
Score = 37.4 bits (85), Expect = 0.046
Identities = 42/238 (17%), Positives = 93/238 (39%), Gaps = 32/238 (13%)
Query: 435 REEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKE 494
++EKR H RV+E + ++ +RH + ++ A +W++Q + +E
Sbjct: 101 KDEKRKEKWKHARVKEREHERRKRHREE-------------QDKARREWERQKRREMARE 147
Query: 495 NREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENE 554
+ R + +Q E++ R + + + ER + E E E
Sbjct: 148 HSRRERDRLEQLERKRERERKMR---------EQQKEQREQKERERRAEERRKEREARRE 198
Query: 555 LTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYR 614
++ + + +Y S+ V + R+ R P+ + R ++ + R
Sbjct: 199 VSAHHRTMREDY----------SDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 248
Query: 615 KKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
++ D DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 249 DLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 306
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 63.9 bits (154), Expect = 5e-10
Identities = 61/230 (26%), Positives = 89/230 (38%), Gaps = 32/230 (13%)
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGEDSSEE 185
HSR D L + + E K R +K QRE +E E E ++ R E S+
Sbjct: 158 HSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 213
Query: 186 KHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEK 228
+ + E P + + RK K EE S+ S+ K
Sbjct: 214 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERK 273
Query: 229 THSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS 288
T S E SS ESG + +E +E + + + EESEE EE+ E ++ G +
Sbjct: 274 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET--------GSN 325
Query: 289 RPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
+ S Q SEE+ EE E N + + D S +EEE
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
Score = 60.8 bits (146), Expect = 4e-09
Identities = 76/388 (19%), Positives = 146/388 (37%), Gaps = 58/388 (14%)
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEA----------GAP--- 107
+KT + +++K+ + + K E++ L++ D +S GE +P
Sbjct: 10 VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR 69
Query: 108 -------GEEDIQGPTKADTEKWAEGGGHSRE---RADEPQWSLYPSDSQVSEEVKTRHS 157
GEED K + + H R+ R ++ + + ++ VK R
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREH 129
Query: 158 EKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARS 217
E+ +R EE+++ + ++ + + E H + +R++ +++++ R
Sbjct: 130 ERRKRHREEQDKARREWERQKRREMARE-HSRRERDRLEQLERKRERERKMREQQKEQRE 188
Query: 218 ETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQ---------PRSQEESEEGEE 268
+ ++E+ RE + S +E++ + K PR + E +G +
Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 248
Query: 269 DATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHH 328
E + R S +R + S E G EE EE E+ +
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE-------EEEEEE 301
Query: 329 STHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRN 388
+ SEEE E EE + G + E + E A EE ++E++ N
Sbjct: 302 GSTSEESEEEEEEEEEEEEETGSNSEE-----------ASEQSAEEVSEEEMSEDEEREN 350
Query: 389 ------YPSLELDKMAHGYGEESEEERG 410
P D+ + G EE+EEE G
Sbjct: 351 ENHLLVVPESRFDRDS-GESEEAEEEVG 377
Score = 51.2 bits (121), Expect = 3e-06
Identities = 56/206 (27%), Positives = 84/206 (40%), Gaps = 51/206 (24%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
S +PP P R L RK VK+++ E + LL D D S++ +S E+ +
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSS- 281
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
AE G S E +E + EE + SE+S+ E+EEE
Sbjct: 282 ----------------AESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEEE 315
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
EE E + G E++SE+ EE E + + ER+ +E H +
Sbjct: 316 EE-EEEETGSNSEEASEQS-AEEVSEEEMSEDEERE-------------NENHLLVVPES 360
Query: 228 KTHSREKSSQESGEETGSQENHPQES 253
+ S+E+ EE G E PQ S
Sbjct: 361 RFDRDSGESEEAEEEVG--EGTPQSS 384
Score = 39.3 bits (90), Expect = 0.012
Identities = 47/235 (20%), Positives = 87/235 (37%), Gaps = 23/235 (9%)
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDK 504
HHR E + +K R H A EG ++ + + K +REE QDK
Sbjct: 98 HHRKDEKRKEKCRHHSHSA-------------EGGKHARVKEREHERRKRHREE---QDK 141
Query: 505 QYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFP 564
++R+ E D L+ ER M + E E+ E +
Sbjct: 142 ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRK 201
Query: 565 EYN-------YDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKS 617
E + ++ +S+ V + R+ R P+ + R ++ + R
Sbjct: 202 EREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLL 261
Query: 618 AEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
++ D DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 316
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 63.9 bits (154), Expect = 5e-10
Identities = 88/392 (22%), Positives = 153/392 (39%), Gaps = 45/392 (11%)
Query: 158 EKSQREDEEEE-------EGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKK 210
E+ Q+E +E+E + E YQK E E +++ + + E+K
Sbjct: 76 EQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLD 135
Query: 211 EELVARSETHAAGHSQEKTHSREKSSQESG-----EETGSQENHPQESKGQ---PRSQE- 261
+ELV R E +K E Q+ G E+ Q HP++ +GQ P QE
Sbjct: 136 QELVKRDEQ----LGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEG 191
Query: 262 -----ESEEGEEDATSEVDKRRTRPRHHHGR-SRPDRSSQGGSLPSEEKGHPQEESEESN 315
E +EG+ + + + + P G+ P++ LP +++G Q E E
Sbjct: 192 QLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEG--QLELSEQQ 249
Query: 316 VSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWE-RYRGRGSEEYRAPR 374
L E+++ H E + E EE G ++ E E + ++ + ++ P
Sbjct: 250 EGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQ--LKYLEQQEGQLKHLDQQEKQPELPE 307
Query: 375 PQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERG----LEPGKGR-----HHRGRGGE 425
Q + E + P L++ G E+ EE+ G LE +G+ H G+ G
Sbjct: 308 QQMGQLKHLEQQEGQPK-HLEQQ-EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGL 365
Query: 426 PRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKEL--DRNYLNYGEEGAPGKW 483
P + + EK+ G+ H +E K +G K L L E
Sbjct: 366 PEQQVLQLKQLEKQ-QGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
Query: 484 QQQGDLQDTKENREEARFQDKQYSSHHTAEKR 515
QQ G L+ +E + + ++Q E++
Sbjct: 425 QQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQ 456
Score = 30.8 bits (68), Expect = 4.3
Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 6/118 (5%)
Query: 148 VSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASA 207
V +E + +H + + + E++E + + + G+ KHLEE E Q L E++Q
Sbjct: 397 VQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQ----LKHLEEQ-EGQLKHL-EQQQGQL 450
Query: 208 IKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEE 265
E+ V + + Q + +++ + E+ +Q P++ GQP+ E+ E+
Sbjct: 451 EVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEK 508
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 63.9 bits (154), Expect = 5e-10
Identities = 61/230 (26%), Positives = 89/230 (38%), Gaps = 32/230 (13%)
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGEDSSEE 185
HSR D L + + E K R +K QRE +E E E ++ R E S+
Sbjct: 149 HSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 204
Query: 186 KHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEK 228
+ + E P + + RK K EE S+ S+ K
Sbjct: 205 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERK 264
Query: 229 THSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS 288
T S E SS ESG + +E +E + + + EESEE EE+ E ++ G +
Sbjct: 265 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET--------GSN 316
Query: 289 RPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
+ S Q SEE+ EE E N + + D S +EEE
Sbjct: 317 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 366
Score = 57.4 bits (137), Expect = 4e-08
Identities = 72/378 (19%), Positives = 137/378 (36%), Gaps = 47/378 (12%)
Query: 61 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEE-DIQGPTKAD 119
+KT + +++K+ + + K E++ L++ D +S GE E I+
Sbjct: 10 VKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR 69
Query: 120 TEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERG 179
+ + G A +P + + + + R +K R E+E E E ++
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 180 EDSSEEK------------HLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
+D + + H + +R++ +++++ R + ++E
Sbjct: 130 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 189
Query: 228 KTHSREKSSQESGEETGSQENHPQESKGQ---------PRSQEESEEGEEDATSEVDKRR 278
+ RE + S +E++ + K PR + E +G + E + R
Sbjct: 190 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 249
Query: 279 TRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
S +R + S E G EE EE E+ + + SEEE
Sbjct: 250 DLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE-------EEEEEEGSTSEESEEE 302
Query: 339 PEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRN------YPSL 392
E EE + G + E + E A EE ++E++ N P
Sbjct: 303 EEEEEEEEEETGSNSEE-----------ASEQSAEEVSEEEMSEDEERENENHLLVVPES 351
Query: 393 ELDKMAHGYGEESEEERG 410
D+ + G EE+EEE G
Sbjct: 352 RFDRDS-GESEEAEEEVG 368
Score = 52.0 bits (123), Expect = 2e-06
Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 61/239 (25%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAP 107
S +PP P R L RK VK+++ E + LL D D S++ +S E+ +
Sbjct: 221 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSS- 272
Query: 108 GEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEE 167
AE G S E +E + EE + SE+S+ E+EEE
Sbjct: 273 ----------------AESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEEE 306
Query: 168 EEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQE 227
EE E + G E++SE+ A + +EE+ E H
Sbjct: 307 EE-EEEETGSNSEEASEQ------------------SAEEVSEEEMSEDEERENENHLLV 347
Query: 228 KTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEG---EEDATSEVDKRRTRPRH 283
SR ++SGE S+E + +G P+S +E + A S ++ ++ P++
Sbjct: 348 VPESR--FDRDSGE---SEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKY 401
Score = 37.0 bits (84), Expect = 0.060
Identities = 41/229 (17%), Positives = 89/229 (38%), Gaps = 20/229 (8%)
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEG-APGKWQQQGDLQDTKENREEARFQD 503
HHR E + +K + +E +R + E+ A +W++Q + +E+ R +
Sbjct: 98 HHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRL 157
Query: 504 KQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFF 563
+Q E++ R + + + ER + E E E++ + +
Sbjct: 158 EQLERKRERERKMR---------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 208
Query: 564 PEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDF 623
+Y S+ V + R+ R P+ + R ++ + R ++ D
Sbjct: 209 EDY----------SDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 258
Query: 624 YDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 259 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 307
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 63.9 bits (154), Expect = 5e-10
Identities = 61/230 (26%), Positives = 89/230 (38%), Gaps = 32/230 (13%)
Query: 129 HSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEE---EGENYQKGERGEDSSEE 185
HSR D L + + E K R +K QRE +E E E ++ R E S+
Sbjct: 115 HSRRERDR----LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 170
Query: 186 KHLEE-----------------PGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEK 228
+ + E P + + RK K EE S+ S+ K
Sbjct: 171 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERK 230
Query: 229 THSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRS 288
T S E SS ESG + +E +E + + + EESEE EE+ E ++ G +
Sbjct: 231 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET--------GSN 282
Query: 289 RPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEE 338
+ S Q SEE+ EE E N + + D S +EEE
Sbjct: 283 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 332
Score = 53.1 bits (126), Expect = 8e-07
Identities = 57/276 (20%), Positives = 105/276 (38%), Gaps = 36/276 (13%)
Query: 150 EEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIK 209
+E + H + + +E+++ +++ +R E + E E Q ER++ ++
Sbjct: 80 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK--MR 137
Query: 210 KEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQ---------PRSQ 260
+++ R + ++E+ RE + S +E++ + K PR +
Sbjct: 138 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 197
Query: 261 EESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMAS 320
E +G + E + R S +R + S E G EE EE
Sbjct: 198 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE----- 252
Query: 321 LGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEES 380
E+ + + SEEE E EE + G + E + E A EE
Sbjct: 253 --EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE-----------ASEQSAEEVSEEEM 299
Query: 381 WDEEDKRN------YPSLELDKMAHGYGEESEEERG 410
++E++ N P D+ + G EE+EEE G
Sbjct: 300 SEDEERENENHLLVVPESRFDRDS-GESEEAEEEVG 334
Score = 48.1 bits (113), Expect = 3e-05
Identities = 64/323 (19%), Positives = 116/323 (35%), Gaps = 61/323 (18%)
Query: 162 REDEEEEEGENYQKGE----------RGEDSSEEKHLEEPGETQNAFLNERKQASAIK-- 209
+ D+ + + ++ ++GE R E +E+ GE ++ + Q + K
Sbjct: 3 QSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK 62
Query: 210 ---KEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQ--EESE 264
+++ + + HA +E+ H R K +E Q+ +E + Q R + E
Sbjct: 63 VHHRKDEKRKEKKHARVKEKEREHERRKRHREE------QDKARREWERQKRREMAREHS 116
Query: 265 EGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEK 324
E D +++++R R R + + R + +EE+ +E E
Sbjct: 117 RRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREV---------- 166
Query: 325 RDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYR-GRGSEEYRAPRPQSEESWDE 383
S H+R E +Y +++K ++P ER+ G G +P EE +E
Sbjct: 167 ----SAHHRTMRE--DYSDKVKASHWSRSPPRPPRERFELGDGR------KPVKEEKMEE 214
Query: 384 ED-----------KRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMS 432
D +R S E G G E EEE E G E
Sbjct: 215 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE----EEEEGSTSEESEEEEE 270
Query: 433 DTREEKRFLGEGHHRVQENQMDK 455
+ EE+ G E ++
Sbjct: 271 EEEEEEEETGSNSEEASEQSAEE 293
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 21/167 (12%)
Query: 48 SSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHES-----SSRG 102
S +PP P R L RK VK+++ E + LL D D S++ SS
Sbjct: 187 SRSPPRPPRERFELGDGRKPVKEEKMEERD-------LLSDLQDISDSERKTSSAESSSA 239
Query: 103 EAGAPGEEDIQGPTKADTE-KWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQ 161
E+G+ EE+ + + + E +E E +E + + + SE+ SE+
Sbjct: 240 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 299
Query: 162 REDEEEEEGENY----QKGERGEDSSEEKHLEE---PGETQNAFLNE 201
ED EE E EN+ + DS E + EE G Q++ L E
Sbjct: 300 SED-EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 345
Score = 37.0 bits (84), Expect = 0.060
Identities = 41/229 (17%), Positives = 89/229 (38%), Gaps = 20/229 (8%)
Query: 445 HHRVQENQMDKARRHPQGAWKELDRNYLNYGEEG-APGKWQQQGDLQDTKENREEARFQD 503
HHR E + +K + +E +R + E+ A +W++Q + +E+ R +
Sbjct: 64 HHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRL 123
Query: 504 KQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFF 563
+Q E++ R + + + ER + E E E++ + +
Sbjct: 124 EQLERKRERERKMR---------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 174
Query: 564 PEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDF 623
+Y S+ V + R+ R P+ + R ++ + R ++ D
Sbjct: 175 EDY----------SDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 224
Query: 624 YDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEK 672
DSE S+ + + E + E+E++E E + + E ++ E+
Sbjct: 225 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 273
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 63.5 bits (153), Expect = 6e-10
Identities = 65/307 (21%), Positives = 120/307 (39%), Gaps = 19/307 (6%)
Query: 47 KSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAH-ESSSRGEAG 105
+ SA T E R++ R D K + + ++ E + +D +H + S + G
Sbjct: 155 QDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEG 214
Query: 106 APGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSD--SQVSEEVKTRHSEKSQ-- 161
++ ++ + G S+E + + + SQ+ E + KS+
Sbjct: 215 MQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRIS 274
Query: 162 REDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHA 221
ED+ E +N E DS+E + + G +Q + + + KE L +
Sbjct: 275 EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPR-RDSKGDSQEDSKENLSQEESQNV 333
Query: 222 AGHSQEKTHSREKSSQESGEETGSQENHPQESKGQP--------RSQEESEEGEEDATSE 273
G S E + SSQE+ E SQE ES+G QE+S+ EED++
Sbjct: 334 DGPSSESSQEANLSSQENSSE--SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHT 391
Query: 274 VDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
+ ++ R S SS+ + E P++E+ S + S + S
Sbjct: 392 LSHSKSESREEQADS---ESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 448
Query: 334 ASEEEPE 340
+ E++ +
Sbjct: 449 SEEDDSD 455
Score = 55.5 bits (132), Expect = 2e-07
Identities = 78/339 (23%), Positives = 122/339 (35%), Gaps = 69/339 (20%)
Query: 88 DPADASEAHESSSRGEAGAPG----EEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYP 143
D ASE ES+ +G+ A ++ + D++ EGG ++E E W
Sbjct: 142 DTIQASE--ESAPQGQDSAQDTTSESRELDNEDRVDSKP--EGGDSTQESESEEHWVGGG 197
Query: 144 SDSQVSEEVKTRHSEKSQREDEEE-------------------EEGENYQKGERGEDSSE 184
SD + S + ++ + D+ E E GEN ++ +DS
Sbjct: 198 SDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT-QDSGG 256
Query: 185 EKHLEEPG-----------ETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSRE 233
+ LE P E + L++ +K + S + G SQ + S+
Sbjct: 257 SQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDS-TENSNSRDTGLSQPRRDSKG 315
Query: 234 KSSQESGEETGSQENH----PQESKGQP---RSQEESEEGEEDATSEVDKRRTRPRHHHG 286
S ++S E +E+ P Q SQE S E +E+ SE
Sbjct: 316 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE------------- 362
Query: 287 RSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIK 346
SR D S +++ E + S+ S E R+ + S E + EE
Sbjct: 363 -SRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQAD--SESSESLNFSEE-- 417
Query: 347 GYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEED 385
++PED G S A QSEES EED
Sbjct: 418 ---SPESPEDENSSSQEGLQSHSSSA-ESQSEESHSEED 452
Score = 48.1 bits (113), Expect = 3e-05
Identities = 51/248 (20%), Positives = 100/248 (40%), Gaps = 21/248 (8%)
Query: 58 RQVLKTSR-KDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPT 116
R++ + SR + D+ ++ NT EV+ +D++E S+SR + D +G +
Sbjct: 265 RKIFRKSRISEEDDRSELDDNNTMEEVK-----SDSTE--NSNSRDTGLSQPRRDSKGDS 317
Query: 117 KADT------EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHS------EKSQRED 164
+ D+ E+ G S E + E S + S+ EEV + S ED
Sbjct: 318 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED 377
Query: 165 EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGH 224
+E+ + S E E+ + LN +++ ++E + E +
Sbjct: 378 QEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHS 437
Query: 225 SQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHH 284
S ++ S E S+E ++ + +E S+ SEE + E++ R+ +
Sbjct: 438 SSAESQSEESHSEEDDSDS-QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAY 496
Query: 285 HGRSRPDR 292
H + D+
Sbjct: 497 HNKPIGDQ 504
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/283 (22%), Positives = 96/283 (33%), Gaps = 69/283 (24%)
Query: 88 DPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHS-----------RERADE 136
DP +S AG +E + +A+T+ + GG + R E
Sbjct: 219 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQ---DSGGSQLLEHPSRKIFRKSRISE 275
Query: 137 PQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGE--- 193
D+ EEVK+ +E S D + KG+ EDS E EE
Sbjct: 276 EDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 335
Query: 194 -----TQNAFLNERKQASAIKKEELVARSE----------------------------TH 220
+Q A L+ ++ +S +EE+V+ S +H
Sbjct: 336 PSSESSQEANLSSQENSSE-SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSH 394
Query: 221 AAGHSQEKTHSREKS-----SQESGE----ETGSQENHPQESKGQPRSQEESEEGEEDAT 271
+ S+E+ E S S+ES E E S + Q SQ E EED +
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 272 SEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEES 314
D RS+ D +S SEE G + ES
Sbjct: 455 DSQDS---------SRSKEDSNSTESKSSSEEDGQLKNIEIES 488
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 63.5 bits (153), Expect = 6e-10
Identities = 65/307 (21%), Positives = 120/307 (39%), Gaps = 19/307 (6%)
Query: 47 KSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAH-ESSSRGEAG 105
+ SA T E R++ R D K + + ++ E + +D +H + S + G
Sbjct: 139 QDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEG 198
Query: 106 APGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSD--SQVSEEVKTRHSEKSQ-- 161
++ ++ + G S+E + + + SQ+ E + KS+
Sbjct: 199 MQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRIS 258
Query: 162 REDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHA 221
ED+ E +N E DS+E + + G +Q + + + KE L +
Sbjct: 259 EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPR-RDSKGDSQEDSKENLSQEESQNV 317
Query: 222 AGHSQEKTHSREKSSQESGEETGSQENHPQESKGQP--------RSQEESEEGEEDATSE 273
G S E + SSQE+ E SQE ES+G QE+S+ EED++
Sbjct: 318 DGPSSESSQEANLSSQENSSE--SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHT 375
Query: 274 VDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYR 333
+ ++ R S SS+ + E P++E+ S + S + S
Sbjct: 376 LSHSKSESREEQADS---ESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 432
Query: 334 ASEEEPE 340
+ E++ +
Sbjct: 433 SEEDDSD 439
Score = 55.5 bits (132), Expect = 2e-07
Identities = 78/339 (23%), Positives = 122/339 (35%), Gaps = 69/339 (20%)
Query: 88 DPADASEAHESSSRGEAGAPG----EEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYP 143
D ASE ES+ +G+ A ++ + D++ EGG ++E E W
Sbjct: 126 DTIQASE--ESAPQGQDSAQDTTSESRELDNEDRVDSKP--EGGDSTQESESEEHWVGGG 181
Query: 144 SDSQVSEEVKTRHSEKSQREDEEE-------------------EEGENYQKGERGEDSSE 184
SD + S + ++ + D+ E E GEN ++ +DS
Sbjct: 182 SDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT-QDSGG 240
Query: 185 EKHLEEPG-----------ETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSRE 233
+ LE P E + L++ +K + S + G SQ + S+
Sbjct: 241 SQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDS-TENSNSRDTGLSQPRRDSKG 299
Query: 234 KSSQESGEETGSQENH----PQESKGQP---RSQEESEEGEEDATSEVDKRRTRPRHHHG 286
S ++S E +E+ P Q SQE S E +E+ SE
Sbjct: 300 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE------------- 346
Query: 287 RSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIK 346
SR D S +++ E + S+ S E R+ + S E + EE
Sbjct: 347 -SRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQAD--SESSESLNFSEE-- 401
Query: 347 GYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEED 385
++PED G S A QSEES EED
Sbjct: 402 ---SPESPEDENSSSQEGLQSHSSSA-ESQSEESHSEED 436
Score = 48.1 bits (113), Expect = 3e-05
Identities = 51/248 (20%), Positives = 100/248 (40%), Gaps = 21/248 (8%)
Query: 58 RQVLKTSR-KDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPT 116
R++ + SR + D+ ++ NT EV+ +D++E S+SR + D +G +
Sbjct: 249 RKIFRKSRISEEDDRSELDDNNTMEEVK-----SDSTE--NSNSRDTGLSQPRRDSKGDS 301
Query: 117 KADT------EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHS------EKSQRED 164
+ D+ E+ G S E + E S + S+ EEV + S ED
Sbjct: 302 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED 361
Query: 165 EEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGH 224
+E+ + S E E+ + LN +++ ++E + E +
Sbjct: 362 QEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHS 421
Query: 225 SQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHH 284
S ++ S E S+E ++ + +E S+ SEE + E++ R+ +
Sbjct: 422 SSAESQSEESHSEEDDSDS-QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAY 480
Query: 285 HGRSRPDR 292
H + D+
Sbjct: 481 HNKPIGDQ 488
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/283 (22%), Positives = 96/283 (33%), Gaps = 69/283 (24%)
Query: 88 DPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHS-----------RERADE 136
DP +S AG +E + +A+T+ + GG + R E
Sbjct: 203 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQ---DSGGSQLLEHPSRKIFRKSRISE 259
Query: 137 PQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGE--- 193
D+ EEVK+ +E S D + KG+ EDS E EE
Sbjct: 260 EDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 319
Query: 194 -----TQNAFLNERKQASAIKKEELVARSE----------------------------TH 220
+Q A L+ ++ +S +EE+V+ S +H
Sbjct: 320 PSSESSQEANLSSQENSSE-SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSH 378
Query: 221 AAGHSQEKTHSREKS-----SQESGE----ETGSQENHPQESKGQPRSQEESEEGEEDAT 271
+ S+E+ E S S+ES E E S + Q SQ E EED +
Sbjct: 379 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438
Query: 272 SEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEES 314
D RS+ D +S SEE G + ES
Sbjct: 439 DSQDS---------SRSKEDSNSTESKSSSEEDGQLKNIEIES 472
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,668,146
Number of Sequences: 37866
Number of extensions: 1689179
Number of successful extensions: 20126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 390
Number of HSP's successfully gapped in prelim test: 1058
Number of HSP's that attempted gapping in prelim test: 8159
Number of HSP's gapped (non-prelim): 6089
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.