Guide to the Human Genome
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Search of human proteins with 11496978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11496978 nuclear transcription factor Y, gamma isoform 2
[Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Hom...   653   0.0  
gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Ho...   647   0.0  
gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Ho...   642   0.0  
gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Ho...   564   e-161
gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Ho...   561   e-160
gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]       64   1e-10
gi|8393116 chromatin accessibility complex 1 [Homo sapiens]            59   6e-09
gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo...    56   4e-08
gi|18426973 DR1-associated protein 1 [Homo sapiens]                    56   5e-08
gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Hom...    52   7e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    52   7e-07
gi|221139761 zinc finger protein 853 [Homo sapiens]                    51   1e-06
gi|44890059 involucrin [Homo sapiens]                                  49   6e-06
gi|38788260 bromodomain PHD finger transcription factor isoform ...    47   2e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ...    47   2e-05
gi|38570099 glutamine-rich 1 [Homo sapiens]                            46   4e-05
gi|38570097 glutamine-rich 1 [Homo sapiens]                            46   4e-05
gi|56549696 E1A binding protein p400 [Homo sapiens]                    44   2e-04
gi|110347429 mediator complex subunit 12 [Homo sapiens]                44   2e-04
gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]          44   3e-04
gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]          44   3e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       43   3e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       43   3e-04
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    43   3e-04
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   42   0.001
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   41   0.001
gi|4758010 clock [Homo sapiens]                                        40   0.002
gi|33286444 mastermind-like 2 [Homo sapiens]                           40   0.002
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 40   0.003
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 39   0.009

>gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Homo
           sapiens]
          Length = 335

 Score =  653 bits (1685), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300

Query: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335


>gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Homo
           sapiens]
          Length = 334

 Score =  647 bits (1668), Expect = 0.0
 Identities = 334/335 (99%), Positives = 334/335 (99%), Gaps = 1/335 (0%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG QLYQ
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG-QLYQ 299

Query: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 300 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334


>gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Homo
           sapiens]
          Length = 354

 Score =  642 bits (1655), Expect = 0.0
 Identities = 335/354 (94%), Positives = 335/354 (94%), Gaps = 19/354 (5%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ-------------------QITQTE 281
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ                   QITQTE
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTE 300

Query: 282 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
           VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 301 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 354


>gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Homo
           sapiens]
          Length = 301

 Score =  564 bits (1453), Expect = e-161
 Identities = 300/335 (89%), Positives = 300/335 (89%), Gaps = 34/335 (10%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           A                         QPQ          GQTMQVMQQIITNTGEIQQIP
Sbjct: 181 A-------------------------QPQ---------QGQTMQVMQQIITNTGEIQQIP 206

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ
Sbjct: 207 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 266

Query: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 267 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 301


>gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Homo
           sapiens]
          Length = 297

 Score =  561 bits (1447), Expect = e-160
 Identities = 297/335 (88%), Positives = 297/335 (88%), Gaps = 38/335 (11%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVK 
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVK- 59

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
                                                RNDIAMAITKFDQFDFLIDIVPR
Sbjct: 60  -------------------------------------RNDIAMAITKFDQFDFLIDIVPR 82

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 83  DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 142

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 143 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 202

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ
Sbjct: 203 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 262

Query: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 263 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 297


>gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]
          Length = 117

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 32/81 (39%), Positives = 49/81 (60%)

Query: 34  TVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKR 93
           +V   R+  LPLAR+K ++K D DV +   EA  + A+AA++F+  +   A+   +  KR
Sbjct: 32  SVPGARLSRLPLARVKALVKADPDVTLAGQEAIFILARAAELFVETIAKDAYCCAQQGKR 91

Query: 94  RTLQRNDIAMAITKFDQFDFL 114
           +TLQR D+  AI   D+F FL
Sbjct: 92  KTLQRRDLDNAIEAVDEFAFL 112


>gi|8393116 chromatin accessibility complex 1 [Homo sapiens]
          Length = 131

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 8/101 (7%)

Query: 39  RVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQR 98
           R+  LPL+RI+ IMK   +V  I+ EA VL AKA ++F+  L   ++ H    +++ L  
Sbjct: 15  RLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYSYRHGSGKEKKVLTY 74

Query: 99  NDIAMAITKFDQFDFLIDIVPR--------DELKPPKRQEE 131
           +D+A    + + F FL DI+P+          LK  KR+E+
Sbjct: 75  SDLANTAQQSETFQFLADILPKKILASKYLKMLKEEKREED 115


>gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo
           sapiens]
          Length = 347

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 55/181 (30%), Positives = 78/181 (43%), Gaps = 27/181 (14%)

Query: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           QQ     VQ Q + Q  ++S   +Q  Q++  QP   Q +   +    GQ + +VQA P 
Sbjct: 26  QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84

Query: 210 GQAQQAQSGTGQTMQVMQQI-ITNTGEIQ-----QIPVQLNAGQLQYIRLAQPVSGTQVV 263
           GQ Q          Q +QQI +   G+IQ      + VQ   GQ Q I + QP       
Sbjct: 85  GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP------- 137

Query: 264 QGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL-YQ--------IQQVTMPAGQDLAQ 314
               QT  T  Q  TQ ++    QQ +Q  +GQ + YQ        +QQVT+P    +  
Sbjct: 138 ----QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITI 193

Query: 315 P 315
           P
Sbjct: 194 P 194



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 46/146 (31%), Positives = 61/146 (41%), Gaps = 25/146 (17%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           T+ Q P +   QG QQ Q        IQ GQ +  Q QQGQT             QI+  
Sbjct: 89  TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
           QPQ      Q+ T Q + V  Q +  T E Q I   PV  +   LQ + +         A
Sbjct: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQT 280
             ++G Q+VQ    T  T++ Q T T
Sbjct: 196 ASLAGAQIVQTGANTNTTSSGQGTVT 221


>gi|18426973 DR1-associated protein 1 [Homo sapiens]
          Length = 205

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 45/75 (60%)

Query: 44  PLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAM 103
           P ARIKKIM+ DE++  ++A  PV+ ++A ++F+  L  +A   T+    +T+  + +  
Sbjct: 13  PPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQ 72

Query: 104 AITKFDQFDFLIDIV 118
            I    QFDFL D+V
Sbjct: 73  CIELEQQFDFLKDLV 87


>gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Homo
           sapiens]
          Length = 318

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 58/179 (32%), Positives = 77/179 (43%), Gaps = 38/179 (21%)

Query: 160 QQQGQQTTSSTTTI--QPGQIIIAQPQQGQTTPVTMQVGEGQQVQ------IVQAQPQGQ 211
           +Q    + SST  I  Q GQI     QQ Q  P+ +QV  GQ +       +VQA P GQ
Sbjct: 2   EQYTANSNSSTEQIVVQAGQI----QQQVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQ 57

Query: 212 AQQAQSGTGQTMQVMQQI-ITNTGEIQ-----QIPVQLNAGQLQYIRLAQPVSGTQVVQG 265
            Q          Q +QQI +   G+IQ      + VQ   GQ Q I + QP         
Sbjct: 58  GQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP--------- 108

Query: 266 QIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL-YQ--------IQQVTMPAGQDLAQP 315
             QT  T  Q  TQ ++    QQ +Q  +GQ + YQ        +QQVT+P    +  P
Sbjct: 109 --QTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIP 165



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 46/146 (31%), Positives = 61/146 (41%), Gaps = 25/146 (17%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           T+ Q P +   QG QQ Q        IQ GQ +  Q QQGQT             QI+  
Sbjct: 60  TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 106

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
           QPQ      Q+ T Q + V  Q +  T E Q I   PV  +   LQ + +         A
Sbjct: 107 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 166

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQT 280
             ++G Q+VQ    T  T++ Q T T
Sbjct: 167 ASLAGAQIVQTGANTNTTSSGQGTVT 192



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 58/186 (31%), Positives = 71/186 (38%), Gaps = 35/186 (18%)

Query: 156 QVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQ--VGEGQQVQIVQAQPQGQAQ 213
           QVQGQ    Q +        GQ I+ Q   G      MQ  V   Q +Q +Q  P GQ  
Sbjct: 25  QVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQI- 83

Query: 214 QAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQT---L 270
           Q Q G                  Q + VQ   GQ Q I + QP   T V  GQ QT   +
Sbjct: 84  QIQGG------------------QAVQVQGQQGQTQQIIIQQP--QTAVTAGQTQTQQQI 123

Query: 271 ATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQ-----QVTMPAGQDLAQPMFIQ---SAN 322
           A   QQ+ QT   Q         DG  L Q+       +T+PA   LA    +Q   + N
Sbjct: 124 AVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAA-SLAGAQIVQTGANTN 182

Query: 323 QPSDGQ 328
             S GQ
Sbjct: 183 TTSSGQ 188


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 55/218 (25%), Positives = 82/218 (37%), Gaps = 23/218 (10%)

Query: 119  PRDELKPPKRQEEVRQSVTPAEP---------VQYYFTLAQQPTAVQVQGQQQGQQTTSS 169
            P+  + P   Q  + Q ++P  P          Q      Q P A+  QG  +    T S
Sbjct: 3773 PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQS 3832

Query: 170  TTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQI 229
                 P    +AQ  QG           G ++   Q Q Q Q  Q Q        + Q +
Sbjct: 3833 RVLSSPQ---LAQQGQGLM---------GHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSL 3880

Query: 230  ITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQF 289
            ++++G+ +     +  G LQ ++  Q +   Q +Q Q Q      QQ+ Q ++QQ QQQ 
Sbjct: 3881 MSHSGQPKLSAQPM--GSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQ 3938

Query: 290  SQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDG 327
                  QQ  Q QQ  +   Q   Q  F Q   Q   G
Sbjct: 3939 QLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/187 (31%), Positives = 75/187 (40%), Gaps = 38/187 (20%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQP---------TAVQVQGQQQGQQTTSSTTTIQPG 176
            P RQ  + QS   + P      LAQQ          TA Q Q QQQ QQ  S        
Sbjct: 3823 PHRQVLMTQSRVLSSP-----QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQ 3877

Query: 177  QIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEI 236
            Q +++   Q +                + AQP G  QQ Q    Q  Q+ QQ      + 
Sbjct: 3878 QSLMSHSGQPK----------------LSAQPMGSLQQLQ----QQQQLQQQQQLQQQQQ 3917

Query: 237  QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ 296
            QQ+  Q    QLQ  +L Q     Q+ Q Q Q L    QQ+ Q + QQ QQQF Q    Q
Sbjct: 3918 QQLQQQQ---QLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQ-QQQQQQFQQQQQQQ 3973

Query: 297  QLYQIQQ 303
            Q+  + Q
Sbjct: 3974 QMGLLNQ 3980



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 6/99 (6%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
            QQ    Q Q QQQ QQ       +Q  Q+   Q QQ       +Q  + QQ+Q  Q Q Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQ------QLQQQQQQQLQQQQQQLQ 3956

Query: 210  GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQL 248
             Q QQ Q    Q  Q  Q  + N       P Q    Q+
Sbjct: 3957 QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 60/238 (25%), Positives = 88/238 (36%), Gaps = 20/238 (8%)

Query: 86   IHTEDNKRRTLQRNDIAMAITKFDQFDF-LIDIVPRDELKPPKRQEEVRQSVTPAEPVQY 144
            +H +  K    ++     A  +F + D   + +V   + K  K+ ++VR+       +  
Sbjct: 3534 VHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMA 3593

Query: 145  YFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQ---IIIAQPQQGQTTP----VTMQVGE 197
             +   QQ    Q Q QQQ QQ  S+   + P Q   ++   P  GQ  P       Q   
Sbjct: 3594 EYRNKQQQ---QQQQQQQQQQQHSAVLALSPSQSPRLLTKLP--GQLLPGHGLQPPQGPP 3648

Query: 198  GQQVQIVQAQPQGQAQQAQSG-----TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIR 252
            G Q   ++  P G A   Q G     T    Q  QQ     G +         G L  +R
Sbjct: 3649 GGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLA-LR 3707

Query: 253  LAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQ 310
               P S   + + Q+Q      Q   + + QQ QQQ  Q   GQ   Q QQ   P  Q
Sbjct: 3708 SLGPDSRL-LQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQ 3764



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 6/115 (5%)

Query: 119  PRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTT-IQPGQ 177
            P   L+  ++Q++++Q     +  Q      QQ    Q+Q QQQ QQ        +Q  Q
Sbjct: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ 3952

Query: 178  IIIAQPQQGQTTPVTMQVGEGQ-----QVQIVQAQPQGQAQQAQSGTGQTMQVMQ 227
              + Q QQ Q      Q  + Q     Q + + +  Q Q QQ   G G   + +Q
Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQ 4007


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/230 (29%), Positives = 95/230 (41%), Gaps = 24/230 (10%)

Query: 121 DELKPPKRQEEVRQSVTPAEPVQY-YFTLAQQPTA---VQVQGQQQGQQTTSSTTT---- 172
           +E +P +R+ +++Q     EP Q       QQP     +Q Q QQ GQQ  S        
Sbjct: 80  EETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQ 139

Query: 173 ------IQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVM 226
                 ++P   ++ Q QQ Q      QV E Q++Q  Q Q Q Q  Q Q    Q  Q+ 
Sbjct: 140 SVHHQELKPELQLMHQQQQLQP----QQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQ 195

Query: 227 QQIITNTGEIQQIPVQLNAGQL----QYIRLAQPVSGTQVVQGQIQTLATNAQ-QITQTE 281
           QQ+      +QQ   QL   QL    + ++  Q     + +Q Q Q L    Q Q+ Q  
Sbjct: 196 QQV-QEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL 254

Query: 282 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
           +QQ Q Q  Q    QQ  Q+QQ  +   Q+  Q    Q   Q    Q  Q
Sbjct: 255 LQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQ 304



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 61/199 (30%), Positives = 81/199 (40%), Gaps = 22/199 (11%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+  K Q    Q + P   + +      QP  VQ Q + Q QQ    T   Q  Q++  
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQ-QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQ 190

Query: 182 QPQQGQTTP----VTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
           Q Q  Q       +  Q  + QQ Q++Q Q Q Q QQ Q    Q  Q+ QQ        Q
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQ---QQEQLQQQ--------Q 239

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQ 297
           Q+ +    GQLQ   L Q     Q  Q Q Q L     Q+ Q  + Q Q+Q  Q    QQ
Sbjct: 240 QLLLLQQQGQLQQQLLQQ-----QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ-QQQQQ 293

Query: 298 LYQIQQVTMPAGQDLAQPM 316
           L Q QQ  +   Q    P+
Sbjct: 294 LLQQQQEQLQQQQLQPPPL 312


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 18/189 (9%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+ P++QE   Q   P +         QQ   +++  QQ+GQ         Q GQ+ + 
Sbjct: 222 QLELPEQQEG--QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEH---QEGQLEVP 276

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQ------GQAQQAQSGTGQTMQVMQQIITNTGE 235
           + Q GQ   +  Q G+ + +   + QP+      GQ +  +   GQ   + QQ     G+
Sbjct: 277 EEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQ----EGQ 332

Query: 236 IQQIPVQLNAGQLQYIRLAQ-PVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTD 294
           ++Q+  Q   GQL+++   +  +   +  +GQ+        Q+ Q E QQGQ +  +  +
Sbjct: 333 LEQLEEQ--EGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEE 390

Query: 295 GQQLYQIQQ 303
           GQ  + +QQ
Sbjct: 391 GQLKHLVQQ 399



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 24/197 (12%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+ P++QE   Q   P +         QQ   +++  QQ+GQ   S     Q GQ+ ++
Sbjct: 202 QLELPEQQEG--QLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ---QEGQLELS 256

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPV 241
           + Q+GQ   +  Q G   Q+++ + Q  GQ +  +   GQ   + QQ      E Q    
Sbjct: 257 EQQEGQLKHLEHQEG---QLEVPEEQ-MGQLKYLEQQEGQLKHLDQQ------EKQPELP 306

Query: 242 QLNAGQLQYIRL--AQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG---- 295
           +   GQL+++     QP    Q  +GQ++ L     Q+   E Q+GQ +  +  +G    
Sbjct: 307 EQQMGQLKHLEQQEGQPKHLEQQ-EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGL 365

Query: 296 --QQLYQIQQVTMPAGQ 310
             QQ+ Q++Q+    GQ
Sbjct: 366 PEQQVLQLKQLEKQQGQ 382



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/192 (26%), Positives = 78/192 (40%), Gaps = 29/192 (15%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +LK   +QE  +Q   P + +     L QQ    +   QQ+GQ         Q GQ+   
Sbjct: 292 QLKHLDQQE--KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE---QEGQLKHL 346

Query: 182 QPQQGQTTPVTMQVG-----EGQQVQIVQAQPQ-GQAQQAQSGTGQTMQVMQQIITNTGE 235
           + Q+GQ   +  Q G     E Q +Q+ Q + Q GQ +  +   GQ   ++QQ       
Sbjct: 347 EQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ------- 399

Query: 236 IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG 295
                     GQL++  L Q     +  + Q++ L     Q+   E Q+GQ +  +   G
Sbjct: 400 ---------EGQLKH--LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQG 448

Query: 296 QQLYQIQQVTMP 307
           Q     QQV  P
Sbjct: 449 QLEVPEQQVGQP 460



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 38/178 (21%), Positives = 72/178 (40%), Gaps = 17/178 (9%)

Query: 155 VQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGE--------GQQVQIVQA 206
           VQ +GQ + Q+        Q GQ+   + Q+GQ   +  Q G+        GQ   + Q 
Sbjct: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQP-VSGTQVVQG 265
           + Q +  + Q G  + ++  +  +       ++P Q   GQ +++   +  +   +   G
Sbjct: 467 EKQLELPEQQEGQVKHLEKQEAQL-------ELPEQ-QVGQPKHLEQQEKHLEHPEQQDG 518

Query: 266 QIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQ 323
           Q++ L     Q+   E Q+GQ +   F       Q  Q  +P   ++  P+  Q   Q
Sbjct: 519 QLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 56/219 (25%), Positives = 85/219 (38%), Gaps = 31/219 (14%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P   ++V   +   +PV    T    P  V     Q+   + +ST+ IQ       +PQQ
Sbjct: 2212 PGAPQQVMTQIIRGQPVS---TAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQ 2268

Query: 186  GQTTPVTMQVGE------GQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI 239
            GQ      Q+ +      G Q   V  Q QGQ       TGQ   + Q +    G  QQ+
Sbjct: 2269 GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQL 2322

Query: 240  -PVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL 298
                +  G +Q   L  P++ T        T +T    ++ T    G+Q+ S+ +   Q+
Sbjct: 2323 MQAAMPNGTVQRF-LFTPLATTAT------TASTTTTTVSTTAAGTGEQRQSKLSPQMQV 2375

Query: 299  YQIQQVTMPAGQDL------AQPMFIQSANQPSDGQAPQ 331
            +  Q  T+P  Q        AQP   Q + QP     PQ
Sbjct: 2376 H--QDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQ 2412



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTP-----VTMQVGEGQQVQIV 204
            Q+PT +          T+S+T+TI P Q ++  P  G  T      +T +VG    V   
Sbjct: 2049 QKPTVIATSTTSP---TSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 2105

Query: 205  QAQPQGQ-----AQQAQSGTGQTMQVMQQII----TNTGEIQQ 238
            Q +   Q      +Q QS +G  +QV Q+++    ++TG  QQ
Sbjct: 2106 QNKNFHQTFATWVKQGQSNSG-VVQVQQKVLGIIPSSTGTSQQ 2147


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 56/219 (25%), Positives = 85/219 (38%), Gaps = 31/219 (14%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P   ++V   +   +PV    T    P  V     Q+   + +ST+ IQ       +PQQ
Sbjct: 2086 PGAPQQVMTQIIRGQPVS---TAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQ 2142

Query: 186  GQTTPVTMQVGE------GQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI 239
            GQ      Q+ +      G Q   V  Q QGQ       TGQ   + Q +    G  QQ+
Sbjct: 2143 GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQL 2196

Query: 240  -PVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQL 298
                +  G +Q   L  P++ T        T +T    ++ T    G+Q+ S+ +   Q+
Sbjct: 2197 MQAAMPNGTVQRF-LFTPLATTAT------TASTTTTTVSTTAAGTGEQRQSKLSPQMQV 2249

Query: 299  YQIQQVTMPAGQDL------AQPMFIQSANQPSDGQAPQ 331
            +  Q  T+P  Q        AQP   Q + QP     PQ
Sbjct: 2250 H--QDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQ 2286



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 26/193 (13%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQ-QTTSSTTTIQPGQ----III 180
            P +Q +V+ + +   P+Q + +L      +  QGQ Q Q Q  SST T+  GQ    + +
Sbjct: 2361 PGQQSQVQTTTSQPIPIQPHTSLQ-----IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTV 2415

Query: 181  AQP-----QQGQTTPVTMQVGE-GQQVQI---VQAQPQGQAQQAQSGTGQTMQVMQQIIT 231
            + P     Q  Q  P  + V +  QQVQ+   +Q+Q   Q Q  QSG  Q +++   I  
Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPI-- 2473

Query: 232  NTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQ 291
               +IQQ    +   Q+Q +   Q  S  + +Q ++Q L    Q+  Q +++  ++   Q
Sbjct: 2474 ---QIQQSSA-VQTHQIQNVVTVQAASVQEQLQ-RVQQLRDQQQKKKQQQIEIKREHTLQ 2528

Query: 292  FTDGQQLYQIQQV 304
             ++  ++ Q Q V
Sbjct: 2529 ASNQSEIIQKQVV 2541



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 33/233 (14%)

Query: 125  PPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQ 184
            P + + + +  V     V  +     QPT  Q    Q   Q+   +       + +  P 
Sbjct: 2288 PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPS 2347

Query: 185  QGQ---TTPVTMQVGEGQQVQIVQAQP-------------QGQAQ---QAQSGTGQTM-- 223
            Q +   +TP  +  G+  QVQ   +QP             QGQ Q   Q QS T QT+  
Sbjct: 2348 QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSST-QTLSS 2406

Query: 224  -QVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEV 282
             Q + Q+  ++    Q+  Q+   Q Q I + Q       +Q Q+Q L+    Q+   ++
Sbjct: 2407 GQTLNQVTVSSPSRPQL--QIQQPQPQVIAVPQ-------LQQQVQVLSQIQSQVV-AQI 2456

Query: 283  QQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335
            Q  Q    Q    Q   QIQQ +      +   + +Q+A+     Q  Q   D
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRD 2509



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTP-----VTMQVGEGQQVQIV 204
            Q+PT +          T+S+T+TI P Q ++  P  G  T      +T +VG    V   
Sbjct: 1923 QKPTVIATSTTSP---TSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 1979

Query: 205  QAQPQGQ-----AQQAQSGTGQTMQVMQQII----TNTGEIQQ 238
            Q +   Q      +Q QS +G  +QV Q+++    ++TG  QQ
Sbjct: 1980 QNKNFHQTFATWVKQGQSNSG-VVQVQQKVLGIIPSSTGTSQQ 2021


>gi|38570099 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/245 (26%), Positives = 94/245 (38%), Gaps = 39/245 (15%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAV------------------QVQGQQQGQQTT 167
           P+ Q+E +  V   + VQ    + Q P  V                  QVQ Q QGQ   
Sbjct: 86  PQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQ 145

Query: 168 SSTTTIQPGQIIIAQPQQGQTTPVTMQ-VGEGQQVQIVQAQPQ---GQAQQAQSGTGQTM 223
           S+  +IQ   +    P Q Q   + +Q V   QQ+Q  +   +    Q  QAQ   GQ++
Sbjct: 146 SAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSL 205

Query: 224 QVMQQI-ITNTGEIQQIPVQLNAGQLQYIRLA-----QPVSGTQVVQGQIQTLATNAQQI 277
              QQI I   G +   P Q  + +    R+      QPV   +V      + A + Q +
Sbjct: 206 AGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV 265

Query: 278 -TQTEVQQGQQQF-------SQFTDGQQLYQIQ-QVTMPAGQDLAQPMFIQSANQPSDGQ 328
            T   + QGQQQ            D   LY     +T P G+    P++  SA    D Q
Sbjct: 266 ATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVY--SAQPRGDPQ 323

Query: 329 APQVT 333
              +T
Sbjct: 324 QQSIT 328



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/191 (27%), Positives = 76/191 (39%), Gaps = 16/191 (8%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQII-IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q TA      QQG     + +T   G ++ +A P      P T Q  + Q  Q  Q Q Q
Sbjct: 46  QQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQ 105

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLN-------AGQLQYIRLAQP-VSGTQ 261
            Q QQ+       +     +   T +  Q+ VQ+        A  +Q   L  P  S  Q
Sbjct: 106 VQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQ 165

Query: 262 VVQGQIQTLATNAQQITQTEVQQ----GQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMF 317
             Q Q+Q +   AQQI   E+ +     QQ  +Q   GQ L   QQ+ +     L+ P  
Sbjct: 166 AAQIQVQHVQA-AQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPS 224

Query: 318 IQSANQPSDGQ 328
            Q +  P +G+
Sbjct: 225 QQGS--PREGE 233



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 50/234 (21%), Positives = 81/234 (34%), Gaps = 55/234 (23%)

Query: 141 PVQYYFTLAQQPTAVQV---QGQQQGQQTTSSTTTIQPGQIIIAQPQ-QGQTTPVTMQVG 196
           P+   + ++ QP A  +   QGQQQ      S  +++P  + +        T  +T   G
Sbjct: 253 PITVSYAISGQPVATVLAIPQGQQQ------SYVSLRPDLLTVDSAHLYSATGTITSPTG 306

Query: 197 EGQQVQIVQAQPQGQAQQ-----------------------------------AQSGTGQ 221
           E   + +  AQP+G  QQ                                      GT  
Sbjct: 307 ETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGTTS 366

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTL-----ATNAQQ 276
            ++   + +  T      P Q   G +      Q V+GT   Q   QT+         QQ
Sbjct: 367 VVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGT--YQNTAQTVHIWDPQQQPQQ 424

Query: 277 IT---QTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDG 327
            T   QT   Q QQQ  Q T   Q  Q+ +V   +    +  + + ++ +P +G
Sbjct: 425 QTPQEQTPPPQQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEG 478


>gi|38570097 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/245 (26%), Positives = 94/245 (38%), Gaps = 39/245 (15%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAV------------------QVQGQQQGQQTT 167
           P+ Q+E +  V   + VQ    + Q P  V                  QVQ Q QGQ   
Sbjct: 86  PQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQ 145

Query: 168 SSTTTIQPGQIIIAQPQQGQTTPVTMQ-VGEGQQVQIVQAQPQ---GQAQQAQSGTGQTM 223
           S+  +IQ   +    P Q Q   + +Q V   QQ+Q  +   +    Q  QAQ   GQ++
Sbjct: 146 SAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSL 205

Query: 224 QVMQQI-ITNTGEIQQIPVQLNAGQLQYIRLA-----QPVSGTQVVQGQIQTLATNAQQI 277
              QQI I   G +   P Q  + +    R+      QPV   +V      + A + Q +
Sbjct: 206 AGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV 265

Query: 278 -TQTEVQQGQQQF-------SQFTDGQQLYQIQ-QVTMPAGQDLAQPMFIQSANQPSDGQ 328
            T   + QGQQQ            D   LY     +T P G+    P++  SA    D Q
Sbjct: 266 ATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVY--SAQPRGDPQ 323

Query: 329 APQVT 333
              +T
Sbjct: 324 QQSIT 328



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/191 (27%), Positives = 76/191 (39%), Gaps = 16/191 (8%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQII-IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q TA      QQG     + +T   G ++ +A P      P T Q  + Q  Q  Q Q Q
Sbjct: 46  QQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQ 105

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLN-------AGQLQYIRLAQP-VSGTQ 261
            Q QQ+       +     +   T +  Q+ VQ+        A  +Q   L  P  S  Q
Sbjct: 106 VQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQ 165

Query: 262 VVQGQIQTLATNAQQITQTEVQQ----GQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMF 317
             Q Q+Q +   AQQI   E+ +     QQ  +Q   GQ L   QQ+ +     L+ P  
Sbjct: 166 AAQIQVQHVQA-AQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPS 224

Query: 318 IQSANQPSDGQ 328
            Q +  P +G+
Sbjct: 225 QQGS--PREGE 233



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 50/234 (21%), Positives = 81/234 (34%), Gaps = 55/234 (23%)

Query: 141 PVQYYFTLAQQPTAVQV---QGQQQGQQTTSSTTTIQPGQIIIAQPQ-QGQTTPVTMQVG 196
           P+   + ++ QP A  +   QGQQQ      S  +++P  + +        T  +T   G
Sbjct: 253 PITVSYAISGQPVATVLAIPQGQQQ------SYVSLRPDLLTVDSAHLYSATGTITSPTG 306

Query: 197 EGQQVQIVQAQPQGQAQQ-----------------------------------AQSGTGQ 221
           E   + +  AQP+G  QQ                                      GT  
Sbjct: 307 ETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGTTS 366

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTL-----ATNAQQ 276
            ++   + +  T      P Q   G +      Q V+GT   Q   QT+         QQ
Sbjct: 367 VVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGT--YQNTAQTVHIWDPQQQPQQ 424

Query: 277 IT---QTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDG 327
            T   QT   Q QQQ  Q T   Q  Q+ +V   +    +  + + ++ +P +G
Sbjct: 425 QTPQEQTPPPQQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEG 478


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 62/226 (27%), Positives = 86/226 (38%), Gaps = 27/226 (11%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P  Q + +  +    P      LA+ P              T+    +    + I QPQ+
Sbjct: 2854 PTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQK 2913

Query: 186  --GQTT---PVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
              GQT    PV MQ     + Q VQ Q   Q Q AQ       ++  Q IT  G  Q++ 
Sbjct: 2914 AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVA 2973

Query: 241  VQLN-AGQLQY----IRLAQPVSGTQVVQGQI-----------QTLATNAQQITQTEVQQ 284
                 A + Q+    I  AQ ++G Q VQ QI           QT   + QQ+     Q 
Sbjct: 2974 YAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQA 3033

Query: 285  GQQ--QFSQFT-DGQQLYQIQQVTMPA---GQDLAQPMFIQSANQP 324
              Q    +Q T  GQQ+  I  VT  A    Q L Q   + +A+ P
Sbjct: 3034 SPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAP 3079



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 53/202 (26%), Positives = 77/202 (38%), Gaps = 33/202 (16%)

Query: 128  RQEEVRQSVTPAEPVQYYFTLAQQPTA-VQVQGQQQGQQTTSSTTTI---QPGQIIIAQP 183
            + ++ +  + P  P     +   QPTA VQVQ  Q  QQ +   TT+   +PG ++    
Sbjct: 2782 KMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTG-- 2839

Query: 184  QQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQL 243
                TT   +QV    +V   Q Q QGQ Q       Q       +++    +   P   
Sbjct: 2840 ----TTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSP--- 2892

Query: 244  NAGQLQYIRLAQPVSGTQVVQGQIQTLA--------TNAQQITQTEVQQGQQQFS---QF 292
                     L   V+G  V  GQ Q  A         + QQ+ + + Q  QQQ +   Q 
Sbjct: 2893 -----GVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA 2947

Query: 293  TDG----QQLYQIQQVTMPAGQ 310
              G    QQ    QQ+T P  Q
Sbjct: 2948 AQGPAAVQQKITAQQITTPGAQ 2969



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 17/127 (13%)

Query: 118  VPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQ 177
            +   ++  P  Q++V  +  PA   Q+  T   Q  A ++ G QQ Q      T IQ  +
Sbjct: 2958 ITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ--AQKLAGAQQVQ------TQIQVAK 3009

Query: 178  IIIAQPQQGQTTPVT--MQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGE 235
            +     QQ   TPV    QV    Q    QA PQ  A    +  GQ +Q++  +      
Sbjct: 3010 LPQVVQQQ---TPVASIQQVASASQ----QASPQTVALTQATAAGQQVQMIPAVTATAQV 3062

Query: 236  IQQIPVQ 242
            +QQ  +Q
Sbjct: 3063 VQQKLIQ 3069



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 52/174 (29%), Positives = 64/174 (36%), Gaps = 14/174 (8%)

Query: 135  SVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQ 194
            SVT +  V    T  Q P    V    Q         TI P    + + QQ Q      Q
Sbjct: 2671 SVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQ 2730

Query: 195  VGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA-GQLQYIRL 253
              + QQ Q  Q     Q QQ Q+ T   +QV Q      G+ Q  P Q+ A G+L    L
Sbjct: 2731 QQQQQQQQQQQ-----QQQQQQTTTTSQVQVPQ----IQGQAQS-PAQIKAVGKLTPEHL 2780

Query: 254  AQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMP 307
             +     Q +Q   Q     AQ        Q Q Q SQ    QQ  Q+  VT P
Sbjct: 2781 IK--MQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQ-PPQQQSPQLTTVTAP 2831


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 34/217 (15%)

Query: 119  PRDELKPPKRQEEVRQSVTPA------EPVQYYFTLAQQPTA-VQVQGQQQGQQTTSSTT 171
            P   + PP    +  QS  P+      +P ++   L Q+P+  V  Q    G   TS+  
Sbjct: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRH---LQQRPSGYVHQQAPTYGHGLTSTQR 2015

Query: 172  TIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIIT 231
                 Q +   P     TP++ Q G    V+     P+ Q QQ Q    Q  Q  QQ   
Sbjct: 2016 FSH--QTLQQTPMISTMTPMSAQ-GVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQ--- 2069

Query: 232  NTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQ 291
                      Q    Q  +IR  Q        Q QI       QQ  Q + QQ QQQ  Q
Sbjct: 2070 ----------QQQQQQQYHIRQQQ--------QQQILRQQQQQQQQQQQQQQQQQQQQQQ 2111

Query: 292  FTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ 328
                 Q  Q QQ   P  Q  +QP F +   Q +  Q
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 14/123 (11%)

Query: 127  KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQG 186
            ++Q++ +Q     +  QY+    QQ   ++ Q QQQ QQ                Q QQ 
Sbjct: 2060 QQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ----------QQQQQQ 2109

Query: 187  QTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAG 246
            Q      Q  + QQ    Q QPQ Q Q  + G  QT Q  Q        ++Q+  QL+  
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ----TAALVRQLQQQLSNT 2165

Query: 247  QLQ 249
            Q Q
Sbjct: 2166 QPQ 2168



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 8/127 (6%)

Query: 156  QVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQA 215
            Q Q QQQ QQ        Q  Q  I Q QQ Q           QQ Q  Q Q Q Q QQ 
Sbjct: 2055 QQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILR--------QQQQQQQQQQQQQQQQQ 2106

Query: 216  QSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ 275
            Q    Q  Q  QQ        Q  P      Q Q ++  Q    T  +  Q+Q   +N Q
Sbjct: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166

Query: 276  QITQTEV 282
                T +
Sbjct: 2167 PQPSTNI 2173



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 35/128 (27%), Positives = 43/128 (33%), Gaps = 11/128 (8%)

Query: 204  VQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVV 263
            +Q +P G   Q     G  +   Q+    T  +QQ P+         I    P+S   V 
Sbjct: 1991 LQQRPSGYVHQQAPTYGHGLTSTQRFSHQT--LQQTPM---------ISTMTPMSAQGVQ 2039

Query: 264  QGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQ 323
             G   T     QQ  Q + QQ QQQ  Q    QQ  Q         Q L Q    Q   Q
Sbjct: 2040 AGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099

Query: 324  PSDGQAPQ 331
                Q  Q
Sbjct: 2100 QQQQQQQQ 2107


>gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]
          Length = 713

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 52/177 (29%), Positives = 76/177 (42%), Gaps = 13/177 (7%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQP---QGQAQQAQSGTG 220
           QQ T+S TT   GQ+  +  Q         +  + Q +Q+  AQP     Q Q++Q  T 
Sbjct: 282 QQNTNSLTT-SSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTS 340

Query: 221 QTMQVMQQIITNT-GEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQ 279
           Q  Q++Q I   T   +Q     ++   LQ ++L Q   GT ++Q   QT+  + Q   Q
Sbjct: 341 QA-QIVQGITPQTIHGVQASGQNISQQALQNLQL-QLNPGTFLIQA--QTVTPSGQVTWQ 396

Query: 280 TEVQQGQQQFS----QFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 332
           T   QG Q       Q T  QQ+      T+  GQ  A   F  +    S GQ P +
Sbjct: 397 TFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNL 453


>gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]
          Length = 781

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 52/177 (29%), Positives = 76/177 (42%), Gaps = 13/177 (7%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQP---QGQAQQAQSGTG 220
           QQ T+S TT   GQ+  +  Q         +  + Q +Q+  AQP     Q Q++Q  T 
Sbjct: 350 QQNTNSLTT-SSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTS 408

Query: 221 QTMQVMQQIITNT-GEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQ 279
           Q  Q++Q I   T   +Q     ++   LQ ++L Q   GT ++Q   QT+  + Q   Q
Sbjct: 409 QA-QIVQGITPQTIHGVQASGQNISQQALQNLQL-QLNPGTFLIQA--QTVTPSGQVTWQ 464

Query: 280 TEVQQGQQQFS----QFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 332
           T   QG Q       Q T  QQ+      T+  GQ  A   F  +    S GQ P +
Sbjct: 465 TFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNL 521


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 62/213 (29%), Positives = 80/213 (37%), Gaps = 14/213 (6%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ 182
           L+  ++Q++ +Q       +Q  F    Q    Q Q QQQ QQ           Q  I Q
Sbjct: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQ 233

Query: 183 PQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQ 242
            QQ       +Q+ + QQ Q  Q Q Q QA QAQ    Q    MQQ        Q +P Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ--PPMQQ--PQPPPSQALPQQ 289

Query: 243 LNAGQLQYIRLAQPVSGTQ---VVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLY 299
           L   Q+ + +  QP    Q   V Q Q   L   +Q  TQ  V Q Q    Q    Q   
Sbjct: 290 LQ--QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ--TQPLVSQAQALPGQMLYTQPPL 345

Query: 300 QIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 332
           +  +  M   Q   QP   Q        QA Q+
Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 44/154 (28%), Positives = 52/154 (33%), Gaps = 9/154 (5%)

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
           GQ  P T  +       +  A PQ Q Q  Q    Q  Q  Q        +QQ   Q   
Sbjct: 127 GQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ 186

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ--------ITQTEVQQGQQQFSQFTDGQQ 297
            Q Q  + A       VVQ Q Q      QQ          Q ++QQ QQQ  +     Q
Sbjct: 187 QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ-LQ 245

Query: 298 LYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
           L Q QQ      Q   Q +  Q   Q    Q PQ
Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 55/210 (26%), Positives = 72/210 (34%), Gaps = 23/210 (10%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
           P+ Q +++Q     +  Q  F   QQ    Q Q QQQ QQ  +  + +Q         QQ
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ---------QQ 199

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
            Q       V + QQ+Q  Q Q Q   +       Q  Q  QQ+        Q   QL  
Sbjct: 200 FQAV-----VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL--------QRIAQLQL 246

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVT 305
            Q Q  +  Q     Q +Q Q        QQ      Q   QQ  Q    Q      Q  
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306

Query: 306 M-PAGQDLAQPMFIQSANQPSDGQAPQVTG 334
             P  Q+    +  QS  QP   QA  + G
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 60/233 (25%), Positives = 83/233 (35%), Gaps = 41/233 (17%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ--QGQQTTSSTTTIQPGQIIIAQ-- 182
           ++Q++ +Q++    P+Q       QP   Q   QQ  Q   T       QP Q  +AQ  
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 183 ----PQQGQTTPVTMQVGE--GQQ---------------VQIVQAQPQGQAQQAQSGTGQ 221
               P Q QT P+  Q     GQ                VQ    QPQ Q QQ    T Q
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTE 281
             Q++         +Q I   L  G +       P +    +     ++    Q + Q  
Sbjct: 375 AAQMV------APGVQMITEALAQGGMHIRARFPPTTAVSAIPS--SSIPLGRQPMAQVS 426

Query: 282 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQP----SDGQAP 330
            Q      S  + GQQ+ Q  Q   P  Q   QP   Q ++QP    S G AP
Sbjct: 427 -QSSLPMLSSPSPGQQV-QTPQSMPPPPQPSPQPG--QPSSQPNSNVSSGPAP 475


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 62/213 (29%), Positives = 80/213 (37%), Gaps = 14/213 (6%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ 182
           L+  ++Q++ +Q       +Q  F    Q    Q Q QQQ QQ           Q  I Q
Sbjct: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQ 233

Query: 183 PQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQ 242
            QQ       +Q+ + QQ Q  Q Q Q QA QAQ    Q    MQQ        Q +P Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ--PPMQQ--PQPPPSQALPQQ 289

Query: 243 LNAGQLQYIRLAQPVSGTQ---VVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLY 299
           L   Q+ + +  QP    Q   V Q Q   L   +Q  TQ  V Q Q    Q    Q   
Sbjct: 290 LQ--QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ--TQPLVSQAQALPGQMLYTQPPL 345

Query: 300 QIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 332
           +  +  M   Q   QP   Q        QA Q+
Sbjct: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 44/154 (28%), Positives = 52/154 (33%), Gaps = 9/154 (5%)

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
           GQ  P T  +       +  A PQ Q Q  Q    Q  Q  Q        +QQ   Q   
Sbjct: 127 GQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ 186

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ--------ITQTEVQQGQQQFSQFTDGQQ 297
            Q Q  + A       VVQ Q Q      QQ          Q ++QQ QQQ  +     Q
Sbjct: 187 QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ-LQ 245

Query: 298 LYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
           L Q QQ      Q   Q +  Q   Q    Q PQ
Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 55/210 (26%), Positives = 72/210 (34%), Gaps = 23/210 (10%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
           P+ Q +++Q     +  Q  F   QQ    Q Q QQQ QQ  +  + +Q         QQ
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ---------QQ 199

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
            Q       V + QQ+Q  Q Q Q   +       Q  Q  QQ+        Q   QL  
Sbjct: 200 FQAV-----VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL--------QRIAQLQL 246

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVT 305
            Q Q  +  Q     Q +Q Q        QQ      Q   QQ  Q    Q      Q  
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306

Query: 306 M-PAGQDLAQPMFIQSANQPSDGQAPQVTG 334
             P  Q+    +  QS  QP   QA  + G
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 17/106 (16%)

Query: 125 PPKRQEEVRQSVTPAEPVQYYFT------------LAQQPTAVQVQGQQQGQQTTSSTTT 172
           PP+ Q +   S   A P Q  +T            + Q P   QVQ QQ   QT  +   
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378

Query: 173 IQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSG 218
           + PG + ++Q     + P+      GQQVQ  Q+ P       Q G
Sbjct: 379 VAPG-VQVSQ----SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 419



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 35/125 (28%), Positives = 47/125 (37%), Gaps = 25/125 (20%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ--QGQQTTSSTTTIQPGQIIIAQ-- 182
           ++Q++ +Q++    P+Q       QP   Q   QQ  Q   T       QP Q  +AQ  
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 183 ----PQQGQTTPVTMQVGE--GQQ---------------VQIVQAQPQGQAQQAQSGTGQ 221
               P Q QT P+  Q     GQ                VQ    QPQ Q QQ    T Q
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 222 TMQVM 226
             Q++
Sbjct: 375 AAQMV 379


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 63/221 (28%), Positives = 77/221 (34%), Gaps = 52/221 (23%)

Query: 119 PRDELKP--PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPG 176
           P+ +  P  P  Q + +Q   P  P Q   T AQ   A Q Q   Q QQ           
Sbjct: 418 PKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPA-QAQATPQHQQ----------- 465

Query: 177 QIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEI 236
           Q+ + Q QQ Q  P   Q            QP G   Q Q    Q  Q +    T    I
Sbjct: 466 QLFLKQQQQQQQPPPAQQ------------QPAGTFYQQQQAQTQQFQAVHP-ATQQPAI 512

Query: 237 QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ 296
            Q PV    G  Q                  Q +    QQ  Q + QQ QQQ +     Q
Sbjct: 513 AQFPVVSQGGSQQ------------------QLMQNFYQQQQQQQQQQQQQQLATALHQQ 554

Query: 297 QLYQ-----IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 332
           QL        Q+ TM AGQ   QP    +A QP+  Q P +
Sbjct: 555 QLMTQQAALQQKPTMAAGQQ-PQPQ-PAAAPQPAPAQEPAI 593


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 62/219 (28%), Positives = 86/219 (39%), Gaps = 33/219 (15%)

Query: 115 IDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQ 174
           + + P   +   ++Q + +Q   P         L  QP  +    QQQ QQ +      Q
Sbjct: 392 VKVTPETHMLQQQQQAQQQQQQHPV--------LHLQPQQIMQLQQQQQQQISQQPYPQQ 443

Query: 175 PGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQ--PQGQAQQAQSGTGQTMQVMQQIITN 232
           P     +Q QQ Q      Q  + QQ+Q  Q Q  P  Q  + Q    Q +Q  QQ    
Sbjct: 444 PPH-PFSQQQQQQQQAHPHQFSQ-QQLQFPQQQLHPPQQLHRPQ----QQLQPFQQ---- 493

Query: 233 TGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQF 292
              +QQ   QL   QLQ  +LAQ      ++Q Q Q      QQI Q ++Q+  QQ    
Sbjct: 494 QHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ------QQIQQQQLQRMHQQ---- 543

Query: 293 TDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
              QQ  Q+Q  T P     +Q +  Q   Q    Q  Q
Sbjct: 544 ---QQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQ 579



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 56/195 (28%), Positives = 68/195 (34%), Gaps = 17/195 (8%)

Query: 155 VQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTT---PVTMQVGEG---QQVQIVQAQP 208
           +Q Q Q Q QQ       +QP QI+  Q QQ Q     P   Q       QQ Q  QA P
Sbjct: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHP 460

Query: 209 QGQAQQAQSGTGQTMQVMQQI---------ITNTGEIQQIPVQLNAGQLQYIRLAQPVSG 259
              +QQ      Q +   QQ+               +QQ   QL   QLQ  +LAQ    
Sbjct: 461 HQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520

Query: 260 TQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQ 319
             ++Q Q Q      Q     + QQ QQ  SQ      L Q  Q           P   Q
Sbjct: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ--TAPHLSQTSQALQHQVPPQQPPQQQQ 578

Query: 320 SANQPSDGQAPQVTG 334
               P   Q  Q+ G
Sbjct: 579 QQQPPPSPQQHQLFG 593



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 119 PRDELKPPKRQEEVRQSVTPAEP----VQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQ 174
           P+ +L+P ++Q  ++Q     +      Q    L QQ + +Q Q QQQ QQ        Q
Sbjct: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQ 543

Query: 175 PGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQ 216
             Q    Q  Q QT P   Q  +  Q Q+   QP  Q QQ Q
Sbjct: 544 QQQ----QQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQ 581


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 56/191 (29%), Positives = 72/191 (37%), Gaps = 18/191 (9%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ 182
           LK PK  ++ R    P   V         P  +Q   QQQ          +Q  Q ++ Q
Sbjct: 73  LKSPKSSDKQRPLQVPVS-VAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQ 131

Query: 183 PQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQ 242
            QQ Q      Q  E   +Q++Q Q Q Q QQ Q    Q  Q  QQ        QQ   Q
Sbjct: 132 QQQLQEFYKKQQ--EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQ 182

Query: 243 LNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQ 302
               Q Q     +     Q  Q Q Q LA  AQQ+     QQ   Q  Q    Q L  +Q
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLA--AQQLV---FQQQLLQMQQLQQQQHLLSLQ 237

Query: 303 Q---VTMPAGQ 310
           +   +++P GQ
Sbjct: 238 RQGLISIPPGQ 248



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 52/178 (29%), Positives = 73/178 (41%), Gaps = 20/178 (11%)

Query: 150 QQPTAVQ------VQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQI 203
           QQ  A+Q      +Q Q  G ++  S+   +P Q+ ++         +T QV   QQ+Q 
Sbjct: 53  QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVS------VAMMTPQVITPQQMQQ 106

Query: 204 VQAQPQGQAQQAQSGTGQTMQVM--QQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQ 261
           +  Q     QQ Q+   Q   VM  QQ +    + QQ  + L   Q Q  +  Q     Q
Sbjct: 107 ILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 166

Query: 262 VVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQ 319
             Q Q Q      QQ  Q + QQ QQQ  Q   G+Q  + QQ      Q  AQ +  Q
Sbjct: 167 QQQQQQQ------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 218



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 46/185 (24%), Positives = 68/185 (36%), Gaps = 7/185 (3%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           TL+ Q  A    G+  G  T+S  +T++     +   QQ Q      Q+   QQ   +++
Sbjct: 22  TLSSQLDAGSRDGRSSGD-TSSEVSTVE-----LLHLQQQQALQAARQLLLQQQTSGLKS 75

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQ 266
                 Q+          +  Q+IT   ++QQI  Q      Q   L Q      + Q Q
Sbjct: 76  PKSSDKQRPLQVPVSVAMMTPQVITPQ-QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134

Query: 267 IQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSD 326
           +Q      Q+    ++ Q QQQ  Q    QQ  Q QQ      Q   Q    Q   Q   
Sbjct: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 194

Query: 327 GQAPQ 331
            QA +
Sbjct: 195 KQAKE 199


>gi|4758010 clock [Homo sapiens]
          Length = 846

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 55/179 (30%), Positives = 73/179 (40%), Gaps = 35/179 (19%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQ----GQT----------TPVTMQVGEGQQVQIVQAQPQ 209
           QQT  ST+T     ++    QQ     QT          T V  Q   G  VQI  + PQ
Sbjct: 625 QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIPSSMPQ 684

Query: 210 GQAQQAQSGT-GQTMQVM----QQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQ 264
              Q A   T  Q  Q+     QQ++T   ++   PV   A     + +   +   QVV 
Sbjct: 685 NSTQSAAVTTFTQDRQIRFSQGQQLVT---KLVTAPVACGA-----VMVPSTMLMGQVVT 736

Query: 265 GQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQP--MFIQSA 321
               T AT  QQ     V Q QQQ  Q +  QQL  +QQ   P+   L QP   F+Q++
Sbjct: 737 A-YPTFATQQQQSQTLSVTQQQQQ--QSSQEQQLTSVQQ---PSQAQLTQPPQQFLQTS 789



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 1/79 (1%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ-PQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q  +V  Q QQQ  Q    T+  QP Q  + Q PQQ   T   +      Q+ +  A P 
Sbjct: 749 QTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPL 808

Query: 210 GQAQQAQSGTGQTMQVMQQ 228
            Q+   QS   Q     QQ
Sbjct: 809 QQSTFPQSHHQQHQSQQQQ 827


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 47/164 (28%), Positives = 61/164 (37%), Gaps = 17/164 (10%)

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPV 241
           +P+QG T P+     +    Q+    P          T Q  Q  QQ      + QQ   
Sbjct: 550 EPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ----QQQQQQQQQ 605

Query: 242 QLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQI 301
           Q    Q Q  +  Q  S     Q Q Q  + +AQQ  Q + QQ QQQ  Q    QQ  Q 
Sbjct: 606 QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ-QQQQQQQQQQQQQQQQQQQQQQQQ 664

Query: 302 QQVTMPAGQDLAQP------------MFIQSANQPSDGQAPQVT 333
           Q  + PA    +QP            +  Q  NQP  G   QV+
Sbjct: 665 QPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVS 708



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 15/121 (12%)

Query: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           QQ    Q Q QQQ QQ++           I AQ QQ Q + ++ Q  + QQ Q  Q Q Q
Sbjct: 606 QQQQQQQQQQQQQQQQSS-----------ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGT--QVVQGQI 267
            Q QQ Q     + Q  Q + +    + + P+ L    L      QP++G   QV Q Q 
Sbjct: 655 QQQQQQQQQQQPSSQPAQSLPSQ--PLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQR 712

Query: 268 Q 268
           Q
Sbjct: 713 Q 713



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 43/178 (24%), Positives = 64/178 (35%), Gaps = 25/178 (14%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQP--- 183
           ++Q++ + S++  +  Q      QQ    Q Q QQQ QQ +S      P Q ++  P   
Sbjct: 627 QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPL 686

Query: 184 ------QQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
                 QQ Q  P+    G G QV   Q Q Q       +G   +        T +G + 
Sbjct: 687 QQKLLLQQMQNQPI---AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMN 743

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQVVQGQI----QTLATNAQQITQTEVQQGQQQFSQ 291
                LN          Q +   Q +Q QI    Q L    Q +   E    Q Q ++
Sbjct: 744 SQQSLLN---------QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINR 792


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 55/179 (30%), Positives = 69/179 (38%), Gaps = 19/179 (10%)

Query: 137 TPAEPVQYYFTLAQQPTAVQVQG--QQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQ 194
           T A PV       Q  T  Q+Q   QQQ          +Q  Q ++ Q QQ Q      Q
Sbjct: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168

Query: 195 VGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLA 254
             E   +Q++Q Q Q Q QQ Q    Q  Q  QQ        QQ   Q    Q Q     
Sbjct: 169 --EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQHPG 219

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQ---VTMPAGQ 310
           +     Q  Q Q Q LA  AQQ+     QQ   Q  Q    Q L  +Q+   +++P GQ
Sbjct: 220 KQAKEQQQQQQQQQQLA--AQQLV---FQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQ 273



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ-----QGQQTTSSTTTIQPGQ 177
           + P + Q+ ++Q V   + +Q    L QQ  AV +Q QQ     + QQ       +Q  Q
Sbjct: 124 ITPQQMQQILQQQVLSPQQLQ---ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180

Query: 178 IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
               Q QQ Q      Q  + QQ Q  Q Q Q Q QQ   G     Q  QQ        Q
Sbjct: 181 Q--QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQ 261
           Q+  Q    Q+Q ++  Q +   Q
Sbjct: 239 QLVFQQQLLQMQQLQQQQHLLSLQ 262



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 42/131 (32%), Positives = 54/131 (41%), Gaps = 8/131 (6%)

Query: 191 VTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVM--QQIITNTGEIQQIPVQLNAGQL 248
           +T QV   QQ+Q +  Q     QQ Q+   Q   VM  QQ +    + QQ  + L   Q 
Sbjct: 119 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 178

Query: 249 QYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPA 308
           Q  +  Q     Q  Q Q Q      QQ  Q + QQ QQQ  Q   G+Q  + QQ     
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232

Query: 309 GQDLAQPMFIQ 319
            Q  AQ +  Q
Sbjct: 233 QQLAAQQLVFQ 243



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 34/110 (30%), Positives = 43/110 (39%), Gaps = 10/110 (9%)

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTE 281
           T Q MQQI+      QQ+   L+  QLQ   L Q      + Q Q+Q      Q+    +
Sbjct: 125 TPQQMQQILQ-----QQV---LSPQQLQ--ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 174

Query: 282 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
           + Q QQQ  Q    QQ  Q QQ      Q   Q    Q   Q    QA +
Sbjct: 175 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKE 224


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 17/162 (10%)

Query: 152 PTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ 211
           P  +Q   QQQ          +Q  Q ++ Q QQ Q      Q  E   +Q++Q Q Q Q
Sbjct: 9   PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ--EQLHLQLLQQQQQQQ 66

Query: 212 AQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLA 271
            QQ Q    Q  Q  QQ        QQ   Q    Q Q     +     Q  Q Q Q LA
Sbjct: 67  QQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA 119

Query: 272 TNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQ---VTMPAGQ 310
             AQQ+     QQ   Q  Q    Q L  +Q+   +++P GQ
Sbjct: 120 --AQQLV---FQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQ 156



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ-----QGQQTTSSTTTIQPGQ 177
           + P + Q+ ++Q V   + +Q    L QQ  AV +Q QQ     + QQ       +Q  Q
Sbjct: 7   ITPQQMQQILQQQVLSPQQLQ---ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63

Query: 178 IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
               Q QQ Q      Q  + QQ Q  Q Q Q Q QQ   G     Q  QQ        Q
Sbjct: 64  Q--QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQ 261
           Q+  Q    Q+Q ++  Q +   Q
Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQ 145



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 42/131 (32%), Positives = 54/131 (41%), Gaps = 8/131 (6%)

Query: 191 VTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVM--QQIITNTGEIQQIPVQLNAGQL 248
           +T QV   QQ+Q +  Q     QQ Q+   Q   VM  QQ +    + QQ  + L   Q 
Sbjct: 2   MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 61

Query: 249 QYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPA 308
           Q  +  Q     Q  Q Q Q      QQ  Q + QQ QQQ  Q   G+Q  + QQ     
Sbjct: 62  QQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115

Query: 309 GQDLAQPMFIQ 319
            Q  AQ +  Q
Sbjct: 116 QQLAAQQLVFQ 126



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 180 IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQG---QAQQAQSG-TGQTMQVMQQIITNTGE 235
           +  PQQ Q   +  QV   QQ+Q +  Q Q    Q QQ Q     Q  Q+  Q++    +
Sbjct: 6   VITPQQMQQI-LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 64

Query: 236 IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFS--QFT 293
            QQ   Q    Q Q  +  Q     Q  Q Q Q      Q   Q + QQ QQQ +  Q  
Sbjct: 65  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 124

Query: 294 DGQQLYQIQQV 304
             QQL Q+QQ+
Sbjct: 125 FQQQLLQMQQL 135



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 34/110 (30%), Positives = 43/110 (39%), Gaps = 10/110 (9%)

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTE 281
           T Q MQQI+      QQ+   L+  QLQ   L Q      + Q Q+Q      Q+    +
Sbjct: 8   TPQQMQQILQ-----QQV---LSPQQLQ--ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 57

Query: 282 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 331
           + Q QQQ  Q    QQ  Q QQ      Q   Q    Q   Q    QA +
Sbjct: 58  LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKE 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.127    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,454,021
Number of Sequences: 37866
Number of extensions: 488365
Number of successful extensions: 2461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 107
Number of HSP's that attempted gapping in prelim test: 1872
Number of HSP's gapped (non-prelim): 376
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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