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Search of human proteins with 219842331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219842331 histamine H4 receptor isoform 2 [Homo sapiens]
(302 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219842331 histamine H4 receptor isoform 2 [Homo sapiens] 606 e-174
gi|14251205 histamine H4 receptor isoform 1 [Homo sapiens] 487 e-138
gi|237512996 histamine H4 receptor isoform 3 [Homo sapiens] 124 1e-28
gi|194018562 histamine receptor H3 [Homo sapiens] 119 4e-27
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 72 6e-13
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 71 1e-12
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 70 2e-12
gi|149158709 histamine receptor H1 [Homo sapiens] 70 2e-12
gi|149158706 histamine receptor H1 [Homo sapiens] 70 2e-12
gi|149158704 histamine receptor H1 [Homo sapiens] 70 2e-12
gi|4504491 histamine receptor H1 [Homo sapiens] 70 2e-12
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 68 1e-11
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 67 3e-11
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 67 3e-11
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 67 3e-11
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 67 3e-11
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 67 3e-11
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 65 7e-11
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 65 7e-11
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 65 7e-11
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 65 7e-11
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 65 7e-11
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 65 7e-11
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 65 7e-11
gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens] 65 1e-10
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 63 3e-10
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 62 6e-10
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 62 8e-10
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 61 1e-09
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 59 5e-09
>gi|219842331 histamine H4 receptor isoform 2 [Homo sapiens]
Length = 302
Score = 606 bits (1562), Expect = e-174
Identities = 302/302 (100%), Positives = 302/302 (100%)
Query: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
Sbjct: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
Query: 61 DFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLS 120
DFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLS
Sbjct: 61 DFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLS 120
Query: 121 RCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMN 180
RCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMN
Sbjct: 121 RCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMN 180
Query: 181 SNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSF 240
SNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSF
Sbjct: 181 SNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSF 240
Query: 241 YSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSV 300
YSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSV
Sbjct: 241 YSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSV 300
Query: 301 SS 302
SS
Sbjct: 301 SS 302
>gi|14251205 histamine H4 receptor isoform 1 [Homo sapiens]
Length = 390
Score = 487 bits (1253), Expect = e-138
Identities = 249/293 (84%), Positives = 258/293 (88%), Gaps = 16/293 (5%)
Query: 10 LSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVSESW 69
LS+S V+ + V + L A+ +LAF+V+ +VSESW
Sbjct: 114 LSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVN----------------GPMILVSESW 157
Query: 70 KDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLT 129
KDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLT
Sbjct: 158 KDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLT 217
Query: 130 AVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMG 189
AVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMG
Sbjct: 218 AVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMG 277
Query: 190 SFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKS 249
SFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKS
Sbjct: 278 SFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKS 337
Query: 250 VWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS 302
VWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
Sbjct: 338 VWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS 390
Score = 124 bits (311), Expect = 1e-28
Identities = 64/64 (100%), Positives = 64/64 (100%)
Query: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
Sbjct: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
Query: 61 DFFV 64
DFFV
Sbjct: 61 DFFV 64
>gi|237512996 histamine H4 receptor isoform 3 [Homo sapiens]
Length = 67
Score = 124 bits (311), Expect = 1e-28
Identities = 64/64 (100%), Positives = 64/64 (100%)
Query: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
Sbjct: 1 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 60
Query: 61 DFFV 64
DFFV
Sbjct: 61 DFFV 64
>gi|194018562 histamine receptor H3 [Homo sapiens]
Length = 445
Score = 119 bits (297), Expect = 4e-27
Identities = 78/258 (30%), Positives = 112/258 (43%), Gaps = 58/258 (22%)
Query: 76 CEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY------------------------- 110
C FF WY L S LEF P + V +FN++IY
Sbjct: 188 CYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPE 247
Query: 111 -----------WSLWKRDHLSRCQSHP--------GLTAVSSNICGHSFRGRLSSRRSLS 151
W W++ H H G A + + G G ++S S S
Sbjct: 248 AQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSS 307
Query: 152 ASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRAR 211
S+ S R SL S+ +S ++ +M SQS + + L R R
Sbjct: 308 GSS-------SRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFT------QRFRLSRDR 354
Query: 212 RLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYP 271
++AKSLA+++ +F +CWAPY+L I+ + P WY +FWL W NS VNP+LYP
Sbjct: 355 KVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVP-DYWYETSFWLLWANSAVNPVLYP 413
Query: 272 LCHKRFQKAFLKIFCIKK 289
LCH F++AF K+ C +K
Sbjct: 414 LCHHSFRRAFTKLLCPQK 431
Score = 56.6 bits (135), Expect = 3e-08
Identities = 29/54 (53%), Positives = 39/54 (72%)
Query: 11 SLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV 64
S + LA M+L+ A +LGNALV+LAFV D +LR ++++F LNLAISDF V
Sbjct: 30 SAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLV 83
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 72.0 bits (175), Expect = 6e-13
Identities = 39/137 (28%), Positives = 73/137 (53%), Gaps = 17/137 (12%)
Query: 148 RSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVEL 207
+ +S S E+ HS+ + ++ ++IA K+ FS
Sbjct: 243 KEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFS--------------- 287
Query: 208 LRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNP 267
R ++ AK+L I++G+F +CW P+ + + S +S+ P +V +++ FWL +FNS +NP
Sbjct: 288 -REKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAV-FKVVFWLGYFNSCLNP 345
Query: 268 LLYPLCHKRFQKAFLKI 284
++YP K F++AF++I
Sbjct: 346 IIYPCSSKEFKRAFVRI 362
Score = 38.1 bits (87), Expect = 0.010
Identities = 18/62 (29%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 4 TNSTI-NLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDF 62
+NST+ L ++ +++ + ++GN LVIL+ +++LR ++YF +NLA++D
Sbjct: 33 SNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADL 92
Query: 63 FV 64
+
Sbjct: 93 LL 94
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 71.2 bits (173), Expect = 1e-12
Identities = 37/100 (37%), Positives = 60/100 (60%), Gaps = 6/100 (6%)
Query: 185 ASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSA 244
++K +F S SV L ++ R ++ AK+LAI++GVF +CW P+ F + L
Sbjct: 323 SAKGHTFRSSLSVRL-----LKFSREKKAAKTLAIVVGVFVLCWFPF-FFVLPLGSLFPQ 376
Query: 245 TGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKI 284
P +++ FWL +FNS VNPL+YP + F++AFL++
Sbjct: 377 LKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRL 416
Score = 34.3 bits (77), Expect = 0.14
Identities = 17/43 (39%), Positives = 29/43 (67%), Gaps = 2/43 (4%)
Query: 24 LVAFAIML--GNALVILAFVVDKNLRHRSSYFFLNLAISDFFV 64
L AF +M GN LVIL+ +++L+ ++YF +NLA++D +
Sbjct: 103 LAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLL 145
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 70.5 bits (171), Expect = 2e-12
Identities = 79/350 (22%), Positives = 140/350 (40%), Gaps = 75/350 (21%)
Query: 9 NLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV---- 64
++SL +V L ++L+ A L NA VI + L ++Y +LA++D V
Sbjct: 43 SISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILV 102
Query: 65 ------------------VSESWKDEGSECEPGFFSEWYILA------ITSFLEF----- 95
V + W C ++A IT +E+
Sbjct: 103 MPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRT 162
Query: 96 ----VIPVILVAYFNMNI-----YWSLWK-RDHLSRCQSHPG--LTAVSSNICGHSFRG- 142
+ + LV F+++I +W K + +S C + L V S + F
Sbjct: 163 PKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTL 222
Query: 143 ---RLSSRRSLSASTEVPASFHSERQRRKSSLMF--------SSRTKMNSNT--IASKMG 189
L R + A + + + +R + SS T +NS + S+ G
Sbjct: 223 LLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESG 282
Query: 190 SFSQSDSV------ALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSS 243
S + V AL +++ + R R+ K+L I+LG F VCW P+ + ++V+
Sbjct: 283 SPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKD 342
Query: 244 ATGPKSVWYRIAF-----WLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
A W+ +A WL + NS +NP++Y + ++ F++AF K+ K
Sbjct: 343 A-----CWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK 387
>gi|149158709 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 70.5 bits (171), Expect = 2e-12
Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 5/92 (5%)
Query: 200 HQREHVELL---RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAF 256
H R++V L R R+ AK L ++ F +CW PY +F +V++F + + I
Sbjct: 397 HSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTI-- 454
Query: 257 WLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
WL + NS +NPL+YPLC++ F+K F +I I+
Sbjct: 455 WLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
Score = 28.9 bits (63), Expect = 5.8
Identities = 10/36 (27%), Positives = 20/36 (55%)
Query: 75 ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY 110
+CE F+ + +T+ + F +P +L+ +F IY
Sbjct: 179 KCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIY 214
>gi|149158706 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 70.5 bits (171), Expect = 2e-12
Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 5/92 (5%)
Query: 200 HQREHVELL---RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAF 256
H R++V L R R+ AK L ++ F +CW PY +F +V++F + + I
Sbjct: 397 HSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTI-- 454
Query: 257 WLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
WL + NS +NPL+YPLC++ F+K F +I I+
Sbjct: 455 WLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
Score = 28.9 bits (63), Expect = 5.8
Identities = 10/36 (27%), Positives = 20/36 (55%)
Query: 75 ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY 110
+CE F+ + +T+ + F +P +L+ +F IY
Sbjct: 179 KCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIY 214
>gi|149158704 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 70.5 bits (171), Expect = 2e-12
Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 5/92 (5%)
Query: 200 HQREHVELL---RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAF 256
H R++V L R R+ AK L ++ F +CW PY +F +V++F + + I
Sbjct: 397 HSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTI-- 454
Query: 257 WLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
WL + NS +NPL+YPLC++ F+K F +I I+
Sbjct: 455 WLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
Score = 28.9 bits (63), Expect = 5.8
Identities = 10/36 (27%), Positives = 20/36 (55%)
Query: 75 ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY 110
+CE F+ + +T+ + F +P +L+ +F IY
Sbjct: 179 KCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIY 214
>gi|4504491 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 70.5 bits (171), Expect = 2e-12
Identities = 34/92 (36%), Positives = 54/92 (58%), Gaps = 5/92 (5%)
Query: 200 HQREHVELL---RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAF 256
H R++V L R R+ AK L ++ F +CW PY +F +V++F + + I
Sbjct: 397 HSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTI-- 454
Query: 257 WLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
WL + NS +NPL+YPLC++ F+K F +I I+
Sbjct: 455 WLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
Score = 28.9 bits (63), Expect = 5.8
Identities = 10/36 (27%), Positives = 20/36 (55%)
Query: 75 ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIY 110
+CE F+ + +T+ + F +P +L+ +F IY
Sbjct: 179 KCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIY 214
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 67.8 bits (164), Expect = 1e-11
Identities = 44/177 (24%), Positives = 89/177 (50%), Gaps = 23/177 (12%)
Query: 143 RLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSN---------------TIASK 187
+L +++S+ P SF + +S++ + + +NS+ T+A +
Sbjct: 407 KLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKR 466
Query: 188 MGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGP 247
++S + +R+ + L++ ++ A++L+ +L F + W PY++ +V +F S P
Sbjct: 467 FALKTRSQ---ITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCI-P 522
Query: 248 KSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIF---CIKKQPLPSQHSRSVS 301
K+ W + +WL + NS VNP+ Y LC+K F+ F + C KK+ Q+ + S
Sbjct: 523 KTFW-NLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQS 578
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/49 (38%), Positives = 33/49 (67%)
Query: 16 VTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV 64
V +AF ++A ++GN LVI++F V+K L+ ++YF L+LA +D +
Sbjct: 69 VFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLII 117
Score = 28.1 bits (61), Expect = 10.0
Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 5/122 (4%)
Query: 75 ECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSN 134
EC F SE I T+ F +PV ++ +YW ++K R + GL A +
Sbjct: 220 ECFIQFLSEPTITFGTAIAAFYMPVTIMTI----LYWRIYKETE-KRTKELAGLQASGTE 274
Query: 135 ICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQS 194
+F S RS S+ S +R+ F TK + S S
Sbjct: 275 AETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSS 334
Query: 195 DS 196
DS
Sbjct: 335 DS 336
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Query: 209 RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPL 268
R ++ AK+L I++G F +CW P+ L + SF+ P ++I FWL + NS +NP+
Sbjct: 266 REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK-PSETVFKIVFWLGYLNSCINPI 324
Query: 269 LYPLCHKRFQKAF---LKIFCI 287
+YP + F+KAF L+I C+
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQCL 346
Score = 33.9 bits (76), Expect = 0.18
Identities = 16/57 (28%), Positives = 32/57 (56%)
Query: 10 LSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVS 66
+++S + L + + +LGN LVIL+ ++L + Y+ +NLA++D + S
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Query: 209 RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPL 268
R ++ AK+L I++G F +CW P+ L + SF+ P ++I FWL + NS +NP+
Sbjct: 266 REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK-PSETVFKIVFWLGYLNSCINPI 324
Query: 269 LYPLCHKRFQKAF---LKIFCI 287
+YP + F+KAF L+I C+
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQCL 346
Score = 33.9 bits (76), Expect = 0.18
Identities = 16/57 (28%), Positives = 32/57 (56%)
Query: 10 LSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVS 66
+++S + L + + +LGN LVIL+ ++L + Y+ +NLA++D + S
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Query: 209 RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPL 268
R ++ AK+L I++G F +CW P+ L + SF+ P ++I FWL + NS +NP+
Sbjct: 266 REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK-PSETVFKIVFWLGYLNSCINPI 324
Query: 269 LYPLCHKRFQKAF---LKIFCI 287
+YP + F+KAF L+I C+
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQCL 346
Score = 33.9 bits (76), Expect = 0.18
Identities = 16/57 (28%), Positives = 32/57 (56%)
Query: 10 LSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVS 66
+++S + L + + +LGN LVIL+ ++L + Y+ +NLA++D + S
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Query: 209 RARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPL 268
R ++ AK+L I++G F +CW P+ L + SF+ P ++I FWL + NS +NP+
Sbjct: 266 REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFK-PSETVFKIVFWLGYLNSCINPI 324
Query: 269 LYPLCHKRFQKAF---LKIFCI 287
+YP + F+KAF L+I C+
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQCL 346
Score = 33.9 bits (76), Expect = 0.18
Identities = 16/57 (28%), Positives = 32/57 (56%)
Query: 10 LSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVS 66
+++S + L + + +LGN LVIL+ ++L + Y+ +NLA++D + S
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTS 77
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 66.6 bits (161), Expect = 3e-11
Identities = 33/99 (33%), Positives = 53/99 (53%)
Query: 190 SFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKS 249
SF + + + + L R R+ K+L I++G F +CW P+ + +VL F S+ +
Sbjct: 320 SFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPT 379
Query: 250 VWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIK 288
+ I WL + NS +NP++Y +K FQ AF KI K
Sbjct: 380 LLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCK 418
Score = 37.7 bits (86), Expect = 0.013
Identities = 16/62 (25%), Positives = 38/62 (61%)
Query: 3 DTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDF 62
+T ++++S +V + + + F +LGNA V+ A ++++L++ ++Y +LA++D
Sbjct: 24 NTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL 83
Query: 63 FV 64
V
Sbjct: 84 MV 85
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 245 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 303
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 304 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 342
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 65.1 bits (157), Expect = 7e-11
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 187 KMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG 246
+ G+ S+S + Q + + AK+L I++G F +CWAP+ + IV F T
Sbjct: 231 RAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY-TV 289
Query: 247 PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFC 286
P VW WL + NS +NP LY +K F++AFL I C
Sbjct: 290 PGQVWTAF-LWLGYINSGLNPFLYAFLNKSFRRAFLIILC 328
Score = 37.7 bits (86), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 15 RVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRH-RSSYFFLNLAISDFFV 64
+V L F+S V +LGN LV++A D+ LR +++YF ++LA +D V
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV 69
>gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens]
Length = 532
Score = 64.7 bits (156), Expect = 1e-10
Identities = 28/81 (34%), Positives = 52/81 (64%), Gaps = 2/81 (2%)
Query: 201 QREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQW 260
+R+ V L++ R+ A++L+ +L F + W PY++ +V +F P ++W+ + +WL +
Sbjct: 428 KRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCV-PVTLWH-LGYWLCY 485
Query: 261 FNSFVNPLLYPLCHKRFQKAF 281
NS VNP+ Y LC++ F+K F
Sbjct: 486 VNSTVNPICYALCNRTFRKTF 506
Score = 37.4 bits (85), Expect = 0.016
Identities = 15/49 (30%), Positives = 33/49 (67%)
Query: 16 VTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV 64
+T+A ++V+ ++GN LV+++F V+ L+ ++Y+ L+LA +D +
Sbjct: 31 ITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLII 79
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 63.2 bits (152), Expect = 3e-10
Identities = 27/89 (30%), Positives = 49/89 (55%)
Query: 201 QREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQW 260
+R+ + R R+ K L I+LG F +CW P+ + ++VL + + WL +
Sbjct: 287 ERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGY 346
Query: 261 FNSFVNPLLYPLCHKRFQKAFLKIFCIKK 289
NS +NP++Y + ++ F++AF KI +K
Sbjct: 347 LNSLINPIIYTVFNEEFRQAFQKIVPFRK 375
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 62.0 bits (149), Expect = 6e-10
Identities = 73/292 (25%), Positives = 126/292 (43%), Gaps = 27/292 (9%)
Query: 11 SLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV------ 64
SL RV + FM+ F + GN +I++ K L +++ L++AI+DF +
Sbjct: 39 SLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMP 98
Query: 65 ------VSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAY-------FNMNIYW 111
V W + C+ ++S +L+ITS I Y ++ I
Sbjct: 99 YSMIRSVENCWYFGLTFCKI-YYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITI 157
Query: 112 SLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSL 171
+ KR L C S PG A G ++ S+ P F+
Sbjct: 158 PVIKR-LLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMA 216
Query: 172 MFSSRTKMNSNTIASKMGSFSQSDSVA---LHQREHVELLRARRLAKSLAILLGVFAVCW 228
F + M I K+ + S+ + A L + ++ ++ + ++ AK+L I++GVF +CW
Sbjct: 217 GFFTPGSMMVG-IYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCW 275
Query: 229 APYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKA 280
P FTI+L + + + P V + W +FNS NPL+Y + F++A
Sbjct: 276 FP-CFFTILLDPFLNFSTP-VVLFDALTWFGYFNSTCNPLIYGFFYPWFRRA 325
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 61.6 bits (148), Expect = 8e-10
Identities = 48/195 (24%), Positives = 88/195 (45%), Gaps = 18/195 (9%)
Query: 90 TSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRS 149
++F F IP+ L+ IY + H + +S I G++
Sbjct: 185 STFGAFYIPLALILILYYKIYRAAKTLYHKRQ----------ASRIAKEEVNGQVLLESG 234
Query: 150 LSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLR 209
++ V S+ E+ S F K++S T+ S F S +R+ + R
Sbjct: 235 EKSTKSVSTSYVLEKSLSDPSTDFD---KIHS-TVRSLRSEFKHEKS---WRRQKISGTR 287
Query: 210 ARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLL 269
R+ A +L ++LG F +CW P+ + +V++ + + +A WL + NS +NPL+
Sbjct: 288 ERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLA-WLGYLNSLINPLI 346
Query: 270 YPLCHKRFQKAFLKI 284
Y + ++ F+KAF K+
Sbjct: 347 YTIFNEDFKKAFQKL 361
Score = 37.0 bits (84), Expect = 0.021
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 12/70 (17%)
Query: 12 LSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDF--------- 62
+ +++ ++ +S +A N+LVI A +V + L H ++Y +LA++DF
Sbjct: 20 MPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPF 79
Query: 63 ---FVVSESW 69
++V ESW
Sbjct: 80 SIVYIVRESW 89
>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
Length = 460
Score = 61.2 bits (147), Expect = 1e-09
Identities = 28/89 (31%), Positives = 54/89 (60%), Gaps = 3/89 (3%)
Query: 199 LHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWL 258
L +R+ L++ ++ A++L+ +L F + W PY++ +V +F P+++W + +WL
Sbjct: 349 LAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCV-PETLW-ELGYWL 406
Query: 259 QWFNSFVNPLLYPLCHKRFQKAF-LKIFC 286
+ NS +NP+ Y LC+K F+ F L + C
Sbjct: 407 CYVNSTINPMCYALCNKAFRDTFRLLLLC 435
Score = 35.0 bits (79), Expect = 0.081
Identities = 15/41 (36%), Positives = 28/41 (68%)
Query: 24 LVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFV 64
L++ A + GN LV+++F V+ L+ ++YF L+LA +D +
Sbjct: 34 LLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLII 74
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 58.9 bits (141), Expect = 5e-09
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 196 SVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIA 255
S+ R + + ++ + LAI+LGVF +CW P+ + T +L+ + P V Y
Sbjct: 325 SLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFI-THILNIHCDCNIPP-VLYSAF 382
Query: 256 FWLQWFNSFVNPLLYPLCHKRFQKAFLKI 284
WL + NS VNP++Y + F+KAFLKI
Sbjct: 383 TWLGYVNSAVNPIIYTTFNIEFRKAFLKI 411
Score = 32.3 bits (72), Expect = 0.53
Identities = 15/48 (31%), Positives = 29/48 (60%)
Query: 19 AFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVS 66
A ++L+ I+ GN LV +A +K L+ ++Y ++LA++D V +
Sbjct: 38 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVAT 85
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,244,846
Number of Sequences: 37866
Number of extensions: 396443
Number of successful extensions: 3378
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 2664
Number of HSP's gapped (non-prelim): 690
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.