Guide to the Human Genome
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Search of human proteins with 219802834

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219802834 transmembrane protein 106C isoform a [Homo
sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219802834 transmembrane protein 106C isoform a [Homo sapiens]      495   e-140
gi|13129026 transmembrane protein 106C isoform a [Homo sapiens]       495   e-140
gi|219802857 transmembrane protein 106C isoform b [Homo sapiens]      448   e-126
gi|219802797 transmembrane protein 106C isoform b [Homo sapiens]      448   e-126
gi|197116389 transmembrane protein 106B [Homo sapiens]                216   1e-56
gi|40254893 transmembrane protein 106B [Homo sapiens]                 216   1e-56
gi|21450796 transmembrane protein 106A [Homo sapiens]                 138   5e-33
gi|4506591 retinal pigment epithelium-specific protein 65kDa [Ho...    32   0.52 
gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens neandert...    30   1.5  
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...    30   1.5  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.5  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.5  
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.5  
gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]               30   1.5  
gi|145587088 hypothetical protein LOC165186 [Homo sapiens]             30   2.0  
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]            28   7.5  
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]            28   7.5  

>gi|219802834 transmembrane protein 106C isoform a [Homo sapiens]
          Length = 250

 Score =  495 bits (1275), Expect = e-140
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180

Query: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240
           SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240

Query: 241 VDCGGNSTAI 250
           VDCGGNSTAI
Sbjct: 241 VDCGGNSTAI 250


>gi|13129026 transmembrane protein 106C isoform a [Homo sapiens]
          Length = 250

 Score =  495 bits (1275), Expect = e-140
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180

Query: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240
           SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240

Query: 241 VDCGGNSTAI 250
           VDCGGNSTAI
Sbjct: 241 VDCGGNSTAI 250


>gi|219802857 transmembrane protein 106C isoform b [Homo sapiens]
          Length = 231

 Score =  448 bits (1152), Expect = e-126
 Identities = 231/250 (92%), Positives = 231/250 (92%), Gaps = 19/250 (7%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV               
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV--------------- 165

Query: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240
               VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 166 ----VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 221

Query: 241 VDCGGNSTAI 250
           VDCGGNSTAI
Sbjct: 222 VDCGGNSTAI 231


>gi|219802797 transmembrane protein 106C isoform b [Homo sapiens]
          Length = 231

 Score =  448 bits (1152), Expect = e-126
 Identities = 231/250 (92%), Positives = 231/250 (92%), Gaps = 19/250 (7%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV               
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV--------------- 165

Query: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240
               VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 166 ----VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 221

Query: 241 VDCGGNSTAI 250
           VDCGGNSTAI
Sbjct: 222 VDCGGNSTAI 231


>gi|197116389 transmembrane protein 106B [Homo sapiens]
          Length = 274

 Score =  216 bits (550), Expect = 1e-56
 Identities = 110/235 (46%), Positives = 154/235 (65%), Gaps = 5/235 (2%)

Query: 19  EDDRDGLLAEREQEEA-----IAQFPYVEFTGRDSITCLTCQGTGYIPTEQVNELVALIP 73
           E+ R+GL+      E      ++QFPYVEFTGRDS+TC TCQGTG IP  Q N+LVALIP
Sbjct: 24  ENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIP 83

Query: 74  HSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFNKQDSLVI 133
           +SDQRLRP+RTK YV+ S+ +CLL SGL VFFLFP S+ V   G+K   V+++ Q   + 
Sbjct: 84  YSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIY 143

Query: 134 LTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPRSEQLVNFTGKAEM 193
           L I  TL I N+N+Y+V V ++++Q+Q+  TV+      N+++I P   + +++T    +
Sbjct: 144 LNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVI 203

Query: 194 GGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNST 248
               SY+Y FCT+  I VHNIV+ M+ +V  +Y G   Q S E + YVDCG N+T
Sbjct: 204 AEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTT 258


>gi|40254893 transmembrane protein 106B [Homo sapiens]
          Length = 274

 Score =  216 bits (550), Expect = 1e-56
 Identities = 110/235 (46%), Positives = 154/235 (65%), Gaps = 5/235 (2%)

Query: 19  EDDRDGLLAEREQEEA-----IAQFPYVEFTGRDSITCLTCQGTGYIPTEQVNELVALIP 73
           E+ R+GL+      E      ++QFPYVEFTGRDS+TC TCQGTG IP  Q N+LVALIP
Sbjct: 24  ENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIP 83

Query: 74  HSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFNKQDSLVI 133
           +SDQRLRP+RTK YV+ S+ +CLL SGL VFFLFP S+ V   G+K   V+++ Q   + 
Sbjct: 84  YSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIY 143

Query: 134 LTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPRSEQLVNFTGKAEM 193
           L I  TL I N+N+Y+V V ++++Q+Q+  TV+      N+++I P   + +++T    +
Sbjct: 144 LNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVI 203

Query: 194 GGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNST 248
               SY+Y FCT+  I VHNIV+ M+ +V  +Y G   Q S E + YVDCG N+T
Sbjct: 204 AEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTT 258


>gi|21450796 transmembrane protein 106A [Homo sapiens]
          Length = 262

 Score =  138 bits (347), Expect = 5e-33
 Identities = 72/200 (36%), Positives = 118/200 (59%), Gaps = 4/200 (2%)

Query: 49  ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
           +TC TCQG+G IP E   +LVALIP+ DQRL+P+ TK +V L++L+CL+ S  +VFFLFP
Sbjct: 57  VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116

Query: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVST 168
            SV+V   G+    V F++ D  + L I   L I N N+Y + VT L+ ++ +++ VV  
Sbjct: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174

Query: 169 YVTTNVSLIPPRSEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIG 228
                +  I P + + + +    ++       Y  CT  EI VH++++ ++ ++  SY+ 
Sbjct: 175 VSNNLLLHIGPLASEQMFYAVATKIRD--ENTYKICTWLEIKVHHVLLHIQGTLTCSYLS 232

Query: 229 LMTQSSLETHHYVDCGGNST 248
              Q   +++ YVDC GN++
Sbjct: 233 HSEQLVFQSYEYVDCRGNAS 252


>gi|4506591 retinal pigment epithelium-specific protein 65kDa [Homo
           sapiens]
          Length = 533

 Score = 32.0 bits (71), Expect = 0.52
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 13/82 (15%)

Query: 170 VTTNVSLIPPRSEQLVNFTGKAEMGGPF--------SYVYFFCTVPEILVHNIVIFMRTS 221
           +  N+  IPP      +   K+E+   F        SYV+ F   P     N ++F+ T 
Sbjct: 202 IAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTP-----NYIVFVETP 256

Query: 222 VKISYIGLMTQSSLETHHYVDC 243
           VKI+    ++  SL   +Y+DC
Sbjct: 257 VKINLFKFLSSWSLWGANYMDC 278


>gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens
           neanderthalensis]
          Length = 347

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 125 FNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVV 166
           F K +SL+I TIMAT+ + N  FY   + S S  +  M+  V
Sbjct: 270 FTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNV 311


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
          isoform d [Homo sapiens]
          Length = 458

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 83


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
          isoform a [Homo sapiens]
          Length = 486

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 49


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
          isoform c [Homo sapiens]
          Length = 502

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 32 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 65


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
          isoform b [Homo sapiens]
          Length = 520

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 83


>gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]
          Length = 347

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 125 FNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVV 166
           F K +SL+I TIMAT+ + N  FY   + S S  +  M+  V
Sbjct: 270 FTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNV 311


>gi|145587088 hypothetical protein LOC165186 [Homo sapiens]
          Length = 1019

 Score = 30.0 bits (66), Expect = 2.0
 Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 24/153 (15%)

Query: 53  TCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVL 112
           T QG G +  EQ+ EL  L+   D R R +   Q + L      L +  +V      +  
Sbjct: 756 TLQGRGEM-VEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPR 814

Query: 113 VDDDGIKV--------VKVTFNKQDSL------VILTIMATLKIRNSNFYTVAVTSLSSQ 158
           + D   KV         K+    ++SL      +I+T+   L  +NS  Y  AV  L + 
Sbjct: 815 LQDSNKKVNQWALESFAKMIPLLRESLHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAM 874

Query: 159 IQYMNTVVSTYVTTNVSLIPPRSEQLVNFTGKA 191
           ++ ++         N+ L+P  + ++   +G+A
Sbjct: 875 VESLD---------NLCLLPALAGRVRFLSGRA 898


>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
          Length = 785

 Score = 28.1 bits (61), Expect = 7.5
 Identities = 12/41 (29%), Positives = 22/41 (53%)

Query: 112 LVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAV 152
           +VD DG+ + K++ +K+    I+TI   L       YT+ +
Sbjct: 301 IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRI 341


>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
          Length = 785

 Score = 28.1 bits (61), Expect = 7.5
 Identities = 12/41 (29%), Positives = 22/41 (53%)

Query: 112 LVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAV 152
           +VD DG+ + K++ +K+    I+TI   L       YT+ +
Sbjct: 301 IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRI 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,786,250
Number of Sequences: 37866
Number of extensions: 342696
Number of successful extensions: 863
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 844
Number of HSP's gapped (non-prelim): 17
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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