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Search of human proteins with 219555642
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
(502 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 1011 0.0
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 1011 0.0
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 474 e-134
gi|56119110 family with sequence similarity 13, member A1 isofor... 287 2e-77
gi|62865869 family with sequence similarity 13, member A1 isofor... 287 2e-77
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 243 2e-64
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 242 5e-64
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 228 7e-60
gi|150170670 piccolo isoform 2 [Homo sapiens] 45 2e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 45 2e-04
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 42 0.002
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 41 0.002
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 40 0.006
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 39 0.011
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 39 0.014
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.014
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 38 0.019
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 38 0.019
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 38 0.019
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 38 0.025
gi|151101151 coiled-coil domain containing 2 isoform b [Homo sap... 38 0.025
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 38 0.025
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 38 0.025
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 38 0.025
gi|58530842 desmoplakin isoform II [Homo sapiens] 37 0.042
gi|169214011 PREDICTED: hypothetical protein [Homo sapiens] 37 0.042
gi|113428768 PREDICTED: hypothetical protein [Homo sapiens] 37 0.042
gi|113428351 PREDICTED: hypothetical protein [Homo sapiens] 37 0.042
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 37 0.042
gi|116517292 cut-like 2 [Homo sapiens] 37 0.055
>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
Length = 585
Score = 1011 bits (2613), Expect = 0.0
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 1 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 60
MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV
Sbjct: 84 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 143
Query: 61 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 120
RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH
Sbjct: 144 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 203
Query: 121 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 180
KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST
Sbjct: 204 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 263
Query: 181 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 240
QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN
Sbjct: 264 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 323
Query: 241 PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP 300
PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP
Sbjct: 324 PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP 383
Query: 301 SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT 360
SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT
Sbjct: 384 SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT 443
Query: 361 IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM 420
IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM
Sbjct: 444 IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM 503
Query: 421 SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 480
SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK
Sbjct: 504 SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 563
Query: 481 HIKAKLRLLEVLISKQDVAKTI 502
HIKAKLRLLEVLISKQDVAKTI
Sbjct: 564 HIKAKLRLLEVLISKQDVAKTI 585
>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
Length = 502
Score = 1011 bits (2613), Expect = 0.0
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 1 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 60
MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV
Sbjct: 1 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 60
Query: 61 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 120
RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH
Sbjct: 61 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 120
Query: 121 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 180
KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST
Sbjct: 121 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 180
Query: 181 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 240
QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN
Sbjct: 181 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 240
Query: 241 PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP 300
PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP
Sbjct: 241 PEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEP 300
Query: 301 SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT 360
SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT
Sbjct: 301 SSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPT 360
Query: 361 IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM 420
IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM
Sbjct: 361 IQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSM 420
Query: 421 SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 480
SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK
Sbjct: 421 SNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYK 480
Query: 481 HIKAKLRLLEVLISKQDVAKTI 502
HIKAKLRLLEVLISKQDVAKTI
Sbjct: 481 HIKAKLRLLEVLISKQDVAKTI 502
>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
Length = 487
Score = 474 bits (1220), Expect = e-134
Identities = 254/327 (77%), Positives = 270/327 (82%), Gaps = 12/327 (3%)
Query: 1 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 60
MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV
Sbjct: 84 MGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETV 143
Query: 61 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 120
RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH
Sbjct: 144 RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVH 203
Query: 121 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 180
KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST
Sbjct: 204 KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPST 263
Query: 181 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSN 240
QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYR + DK
Sbjct: 264 QQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDK--- 320
Query: 241 PEVLKWMNDLAKGRKQL---KELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAG 297
++K + D + KQ+ L + EE+ S P + +QP++ + G
Sbjct: 321 -NLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS---QQPSL-ADPASHLPVG 375
Query: 298 PEPSSSGEETPDAALTCLKERREQLPP 324
+ S E P AL E++E PP
Sbjct: 376 DHLTYSNETEPVRAL-LPDEKKEVKPP 401
Score = 351 bits (900), Expect = 1e-96
Identities = 185/234 (79%), Positives = 197/234 (84%), Gaps = 3/234 (1%)
Query: 272 PKGPPRNLLCEQPTVPRENGKPEAA-GPEPSSSGEETPDAALTCLKERR--EQLPPQEDS 328
P+ P +Q +PR + + G EP + + T K R+ E+ ++
Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
Query: 329 KVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 388
+VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP
Sbjct: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373
Query: 389 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 448
VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA
Sbjct: 374 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKA 433
Query: 449 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 502
LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI
Sbjct: 434 LREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 287 bits (734), Expect = 2e-77
Identities = 185/478 (38%), Positives = 255/478 (53%), Gaps = 59/478 (12%)
Query: 79 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 138
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 540 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 599
Query: 139 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 197
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 600 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 659
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E T QLT+ IQSLK+KIRKFE++FE+EKKYRPSH DK +NPEVLKW NDLAK R+QL
Sbjct: 660 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 719
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCE---QPTVPRENGKPEAAGPEPSSSGEETPDAALTC 314
KE KLK+SEE + N L + + K E S E T ++
Sbjct: 720 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRK 779
Query: 315 LKERREQLPPQEDSK----------------------------VTKQDKNLIKPLYDRYR 346
L+E+R + ED K VTK ++ ++KPLYDRYR
Sbjct: 780 LQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYR 839
Query: 347 IIKQILS----------------TPSLIPTIQEEEDS----DEDRPQGSQQPSLADPASH 386
++KQILS +P L P I+ E S ++ +GS+ S P
Sbjct: 840 LVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFM 899
Query: 387 LPVGDHLT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETR 439
+ + + + ++ + + + D+ +SNLH A++P LL+HL+E R
Sbjct: 900 VTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMR 959
Query: 440 ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 497
+KKR+RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 960 EEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 1017
Score = 29.6 bits (65), Expect = 6.7
Identities = 51/240 (21%), Positives = 89/240 (37%), Gaps = 49/240 (20%)
Query: 239 SNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKG--PPRNLLCEQPTVP-RENGKPEA 295
+ P+ +WM+D KG +E+ G + P + E P++ + + +
Sbjct: 500 TGPDDFEWMSDERKG-----------NEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQD 548
Query: 296 AGPEPSSSGEETPDAALTCL---KERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQIL 352
AG + S E P + LT L K E +P + D + R+I+Q+L
Sbjct: 549 AGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLL 608
Query: 353 ---STPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDE 409
S P L P S + PS P SH ++ DE
Sbjct: 609 DEDSDPMLSPRFYAYGQSRQYLDDTEVPPS--PPNSH-------SFMRRRSSSLGSYDDE 659
Query: 410 KKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 469
++++ P L+ R ++ KK++RK FE++F ++ P D+
Sbjct: 660 QEDLTPAQLT----------------RRIQSLKKKIRK----FEDRFEEEKKYRPSHSDK 699
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 287 bits (734), Expect = 2e-77
Identities = 185/478 (38%), Positives = 255/478 (53%), Gaps = 59/478 (12%)
Query: 79 ETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVG 138
+T+Q N++ Q P S + L D + +P P Q E + E S
Sbjct: 214 DTKQQRNQDAGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQ 273
Query: 139 TSRLLYHITDGDN-PLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDG 197
RL+ + D D+ P+LSPR + QS+++ D E PSPP++ FM RSSS S D
Sbjct: 274 AGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGSYDDE 333
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E T QLT+ IQSLK+KIRKFE++FE+EKKYRPSH DK +NPEVLKW NDLAK R+QL
Sbjct: 334 QEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKFRRQL 393
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCE---QPTVPRENGKPEAAGPEPSSSGEETPDAALTC 314
KE KLK+SEE + N L + + K E S E T ++
Sbjct: 394 KESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEATLESIQRK 453
Query: 315 LKERREQLPPQEDSK----------------------------VTKQDKNLIKPLYDRYR 346
L+E+R + ED K VTK ++ ++KPLYDRYR
Sbjct: 454 LQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVMKPLYDRYR 513
Query: 347 IIKQILS----------------TPSLIPTIQEEEDS----DEDRPQGSQQPSLADPASH 386
++KQILS +P L P I+ E S ++ +GS+ S P
Sbjct: 514 LVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDDSNVKPDFM 573
Query: 387 LPVGDHLT-------YSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETR 439
+ + + + ++ + + + D+ +SNLH A++P LL+HL+E R
Sbjct: 574 VTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLEHLQEMR 633
Query: 440 ADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQD 497
+KKR+RK LR+FE+ FF+Q GR+ QKEDR PMA+EY EYKHIKAKLRLLEVLISK+D
Sbjct: 634 EEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEVLISKRD 691
Score = 29.6 bits (65), Expect = 6.7
Identities = 51/240 (21%), Positives = 89/240 (37%), Gaps = 49/240 (20%)
Query: 239 SNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKG--PPRNLLCEQPTVP-RENGKPEA 295
+ P+ +WM+D KG +E+ G + P + E P++ + + +
Sbjct: 174 TGPDDFEWMSDERKG-----------NEKDGGHTQHFESPTMKIQEHPSLSDTKQQRNQD 222
Query: 296 AGPEPSSSGEETPDAALTCL---KERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQIL 352
AG + S E P + LT L K E +P + D + R+I+Q+L
Sbjct: 223 AGDQEESFVSEVPQSDLTALCDEKNWEEPIPAFSSWQRENSDSDEAHLSPQAGRLIRQLL 282
Query: 353 ---STPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDE 409
S P L P S + PS P SH ++ DE
Sbjct: 283 DEDSDPMLSPRFYAYGQSRQYLDDTEVPPS--PPNSH-------SFMRRRSSSLGSYDDE 333
Query: 410 KKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDR 469
++++ P L+ R ++ KK++RK FE++F ++ P D+
Sbjct: 334 QEDLTPAQLT----------------RRIQSLKKKIRK----FEDRFEEEKKYRPSHSDK 373
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 243 bits (621), Expect = 2e-64
Identities = 165/429 (38%), Positives = 241/429 (56%), Gaps = 47/429 (10%)
Query: 107 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 165
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
Query: 166 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 225
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
Query: 226 QEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPT 285
+E+ +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T
Sbjct: 589 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NT 642
Query: 286 VPRENG------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQ 333
+P+ G +P+ E S E T + L LKE+R + ED KVTK+
Sbjct: 643 LPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKE 702
Query: 334 DKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL----- 387
+++++KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H
Sbjct: 703 ERHIVKPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIK 758
Query: 388 -PVGDHLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLD 433
D + S+E V++ L + + +V+ L +S+ A+MP LL+
Sbjct: 759 EEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLE 818
Query: 434 HLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLI 493
L + RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLI
Sbjct: 819 QLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLI 878
Query: 494 SKQDVAKTI 502
SKQD +K+I
Sbjct: 879 SKQDSSKSI 887
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 242 bits (618), Expect = 5e-64
Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%)
Query: 112 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 170
D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D
Sbjct: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
Query: 171 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 230
PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+
Sbjct: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
Query: 231 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 290
+PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T+P+
Sbjct: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551
Query: 291 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 338
G +P+ E S E T + L LKE+R + ED KVTK++++++
Sbjct: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611
Query: 339 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 391
KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H D
Sbjct: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667
Query: 392 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 438
+ S+E V++ L + + +V+ L +S+ A+MP LL+ L +
Sbjct: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727
Query: 439 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 498
RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD
Sbjct: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
Query: 499 AKTI 502
+K+I
Sbjct: 788 SKSI 791
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 228 bits (582), Expect = 7e-60
Identities = 165/457 (36%), Positives = 241/457 (52%), Gaps = 75/457 (16%)
Query: 107 LADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQ 165
++DG +P P K Q +++S L S R+ +H + D P+LS R F QSQ
Sbjct: 473 VSDGDKWEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQ 531
Query: 166 RFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFE 225
RF DPE S F R SS S + +E +T QL K +Q +KIR+FEE+FE
Sbjct: 532 RFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFE 588
Query: 226 QEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPT 285
+E+ +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T
Sbjct: 589 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NT 642
Query: 286 VPRENG------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSK---- 329
+P+ G +P+ E S E T + L LKE+R + ED K
Sbjct: 643 LPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTK 702
Query: 330 ------------------------VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEE 365
VTK++++++KPLYDRYR++KQ+L+ S+ P +
Sbjct: 703 DHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVL---- 758
Query: 366 DSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEPVRALLPDEKK 411
S + +G QP + +H D + S+E V++ L + +
Sbjct: 759 GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSES 818
Query: 412 EVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQ 465
+V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE F++Q GR+ Q
Sbjct: 819 DVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQ 878
Query: 466 KEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 502
KEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 879 KEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/374 (21%), Positives = 147/374 (39%), Gaps = 34/374 (9%)
Query: 114 ADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPES 173
A P PV + ++ + P + V + + + + + + L E
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQ---------EQEVKTEAEKVILEKVKETLSMEK 1184
Query: 174 APSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEK-FEQEKKYRP 232
P +T Q + +E + + + K I + KIR E+K +EKK P
Sbjct: 1185 IPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPE-EEKIRSEEKKPLLEEKKPTP 1243
Query: 233 SHGD-----KTSNPEVLKWMNDLAKGRKQLKELKLK-----LSEEQGSAPKGPPRNLLCE 282
KTS PE K +DL K + Q+ E KL+ + ++G P+ L
Sbjct: 1244 EDKKLLPEAKTSAPEEQK--HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSG 1301
Query: 283 QP-TVPRENGKP-EAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKN---L 337
P ++P+E+ K + +P PD KE+ E+ + D+ ++Q K+ L
Sbjct: 1302 TPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 338 IKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSN 397
Y I + PSLIPT +++ + SQ+ S + P+ + T +
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL--ESTVLS 1418
Query: 398 ETEPVRALLPDEKKEVK--PPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 455
E + L DEK E K P +S + L E ++ ++++ E ++
Sbjct: 1419 ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 456 FFKQTGRS-PQKED 468
F K + + P +D
Sbjct: 1479 FKKDSQQDIPSSKD 1492
Score = 30.0 bits (66), Expect = 5.1
Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 22/228 (9%)
Query: 172 ESAPSPPST--QQFMMPRSSSRCSCGDGKEPQTITQLTKH------------IQSLKRKI 217
+S+P P T ++ P+ + K P + Q T H SL +
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 218 RKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPR 277
E E+ P DK P+++K DL + + S+ Q A +
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 278 NLLCEQ--------PTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSK 329
L + PT + + A P P+S + + + ++Q+ P + +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 330 VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQ 377
K+ + + P D + K + P PT + + + P+ +Q
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/374 (21%), Positives = 147/374 (39%), Gaps = 34/374 (9%)
Query: 114 ADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPES 173
A P PV + ++ + P + V + + + + + + L E
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQ---------EQEVKTEAEKVILEKVKETLSMEK 1184
Query: 174 APSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEK-FEQEKKYRP 232
P +T Q + +E + + + K I + KIR E+K +EKK P
Sbjct: 1185 IPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPE-EEKIRSEEKKPLLEEKKPTP 1243
Query: 233 SHGD-----KTSNPEVLKWMNDLAKGRKQLKELKLK-----LSEEQGSAPKGPPRNLLCE 282
KTS PE K +DL K + Q+ E KL+ + ++G P+ L
Sbjct: 1244 EDKKLLPEAKTSAPEEQK--HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSG 1301
Query: 283 QP-TVPRENGKP-EAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKN---L 337
P ++P+E+ K + +P PD KE+ E+ + D+ ++Q K+ L
Sbjct: 1302 TPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 338 IKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSN 397
Y I + PSLIPT +++ + SQ+ S + P+ + T +
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL--ESTVLS 1418
Query: 398 ETEPVRALLPDEKKEVK--PPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 455
E + L DEK E K P +S + L E ++ ++++ E ++
Sbjct: 1419 ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 456 FFKQTGRS-PQKED 468
F K + + P +D
Sbjct: 1479 FKKDSQQDIPSSKD 1492
Score = 30.0 bits (66), Expect = 5.1
Identities = 42/228 (18%), Positives = 80/228 (35%), Gaps = 22/228 (9%)
Query: 172 ESAPSPPST--QQFMMPRSSSRCSCGDGKEPQTITQLTKH------------IQSLKRKI 217
+S+P P T ++ P+ + K P + Q T H SL +
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 218 RKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPR 277
E E+ P DK P+++K DL + + S+ Q A +
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 278 NLLCEQ--------PTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSK 329
L + PT + + A P P+S + + + ++Q+ P + +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 330 VTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQ 377
K+ + + P D + K + P PT + + + P+ +Q
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
[Homo sapiens]
Length = 1265
Score = 41.6 bits (96), Expect = 0.002
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 27/169 (15%)
Query: 215 RKIRKFE--EKFEQEKKYRPSHGDKTSNPEVLKWMND---LAKGRKQLKELKLKLSEEQG 269
RK RK+E ++ K+ +P DK + W N +A K L+ K E +
Sbjct: 770 RKKRKYEKPQELSGRKRLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFK---QEPED 826
Query: 270 SAPKGPPRNLLCEQPTVPRENGKPEAAGPE--PSSSGEETPDAALTCLKERREQLPPQED 327
P+ PP+ RE+ ++ P PS+ G E P+ R+ +LP +E
Sbjct: 827 ELPEAPPKT---------RESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKEL 877
Query: 328 SKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDED--RPQG 374
S + L K L + + L+ + P E E E+ RP G
Sbjct: 878 S------RELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPG 920
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 41.2 bits (95), Expect = 0.002
Identities = 104/491 (21%), Positives = 167/491 (34%), Gaps = 105/491 (21%)
Query: 40 RAGTPAHESPQNNAFK-CQETV--RLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVK 96
R G P E + + K C+ V + P + S K+A E D EE + + K
Sbjct: 307 RPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAK 366
Query: 97 DPAPASTQSVLADGTDSADPSPVHKDGQNEAD------SAPEDLHSVG---TSRLLYHIT 147
+P + S L +G+ A + E S P+ H + SR+ H+
Sbjct: 367 EPKKKA--SALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLL 424
Query: 148 DGD--NPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQ 205
D D +P+L C Q L E S+Q + + S G E +
Sbjct: 425 DVDVLSPVLGGACRQAQQP----LGIEDKDDSQSSQDELQSKQSK------GLEERLSPP 474
Query: 206 LT--KHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLK 263
L + QS R + EE P G + PE W G L L+
Sbjct: 475 LPHEERAQSPPRSLATEEE---------PPQGPE-GQPE---WKEAEELGEDSAASLSLQ 521
Query: 264 LSEEQGSAPKGP-------------------------PRNLLCEQPTVPRENGKPEAAGP 298
LS ++ AP P P + PT P PE
Sbjct: 522 LSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVS---PEVRST 578
Query: 299 EPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDR------------YR 346
EP + E+ +AAL ++E Q+ Q+ + + + ++ L ++ ++
Sbjct: 579 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ 638
Query: 347 IIKQILST--PSLIPTIQEEE----------------------DSDEDRPQGSQQPSLAD 382
+Q LS+ L I+EEE +DED+ + Q+ SL
Sbjct: 639 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK 698
Query: 383 PASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK 442
L ++ + R +L K+E++ S A L LRE +
Sbjct: 699 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 758
Query: 443 KRLRKALREFE 453
++ A E E
Sbjct: 759 RKEAVATLEKE 769
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 39.7 bits (91), Expect = 0.006
Identities = 62/294 (21%), Positives = 99/294 (33%), Gaps = 38/294 (12%)
Query: 159 SIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRC-------------------SCGDGKE 199
S F +R + AP PP + SSSR S +E
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208
Query: 200 PQTITQLTKH---IQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQ 256
+ ++ KH +S KRK R K +++ K + +++ P +
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268
Query: 257 LKELKLKLSEEQGSAPKGPPRNLLCEQPT-VPRENGKPEAAGPEPSSSGEETPDAALTCL 315
S + +A K L P+ G+ +A EP ++ + P + T
Sbjct: 269 ASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT 328
Query: 316 KERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGS 375
K+ P ED K++K+ +P R P+ P + E R GS
Sbjct: 329 KQPSS---PYEDKDKDKKEKSATRPSPSPER-SSTGPEPPAPTPLLAE-------RHGGS 377
Query: 376 QQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMP 429
QP P S PV +E P R P + E P + S + + P
Sbjct: 378 PQPLATTPLSQEPVNP----PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427
Score = 31.6 bits (70), Expect = 1.8
Identities = 56/282 (19%), Positives = 95/282 (33%), Gaps = 47/282 (16%)
Query: 33 SQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQV 92
S E + TP E + + Q+TV P + QR+ + + + +E ++
Sbjct: 1501 SSPELNNKCLTPQRERSGSESSVDQKTVARTP-LGQRSRSGSSQELDVKPSASPQERSES 1559
Query: 93 HGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNP 152
D + A T++ L + S V +++ +P S + + D P
Sbjct: 1560 DSSPD-SKAKTRTPLRQRSRSGSSPEV----DSKSRLSPRRSRSGSSPEVK------DKP 1608
Query: 153 LLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQ-----TITQLT 207
+PR S +S+P P + +PR S S G+ P +
Sbjct: 1609 RAAPRAQSGS---------DSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP 1659
Query: 208 KHIQSLKRKIRKFEEKFEQEKKYR--PSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLS 265
+H + R E + K R P S+PE+ + K +LS
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTR---------------KARLS 1704
Query: 266 EEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEET 307
SA P T PR P + PEP+ +
Sbjct: 1705 RRSRSASSSPETR----SRTPPRHRRSPSVSSPEPAEKSRSS 1742
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 38.9 bits (89), Expect = 0.011
Identities = 76/369 (20%), Positives = 135/369 (36%), Gaps = 37/369 (10%)
Query: 82 QDLNEEEAAQVHGVKD---------PAPASTQSVLADGTDSADPSPVHKDGQNEADSAPE 132
Q + + + +VH V++ P P + + S P P KD Q+ +
Sbjct: 343 QSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPT-KDSQHVSSVTQN 401
Query: 133 DLHSVGTSRLLYHITDGDNPLLSPRCSIF----SQSQRFNLDPESAPSPPSTQQFMMPRS 188
+S+ + G + +L + S S++ P S+ +PPS Q +
Sbjct: 402 QKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPV 461
Query: 189 SSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMN 248
+S S E ++ + S E+ E + P T+N KW
Sbjct: 462 ASAHS--SSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN----KWQL 515
Query: 249 DLAKGRKQLKELKLKLSEEQGSAPKGPPR----NLLCEQPTVPRENGKPEAAGPEPSSSG 304
D L ++ + +G PPR + +E+ + + P+ SS
Sbjct: 516 D-----NWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKA 570
Query: 305 EETPDAA-----LTCLKERREQLPPQEDSKVTKQDKNLIK-PLYDRYRIIKQILSTPSLI 358
P A +C K +Q PPQ + TKQ K +K R Q P L+
Sbjct: 571 PRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL 630
Query: 359 PTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPAL 418
P ++ S +D+P+ + AS+ P + S+E + ++ LP K + P
Sbjct: 631 PYGSRDQTS-KDKPKVKTKGRPRAAASNEP-KPAVPPSSEKKKHKSSLPAPSKALSGPEP 688
Query: 419 SMSNLHEAT 427
+ N+ + T
Sbjct: 689 AKDNVEDRT 697
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 38.5 bits (88), Expect = 0.014
Identities = 91/466 (19%), Positives = 159/466 (34%), Gaps = 58/466 (12%)
Query: 21 HGESQETEHVVSSQSE-CQVRAGTP-AHESPQNNAFKCQETVRLQPRIDQRTAISPKDAF 78
HGE E+ S +E + TP A++ +++ + E P ++ T SP +
Sbjct: 383 HGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPT 442
Query: 79 ETRQDL--------------NEEEAAQVHGVKDPA-PASTQSVLADGTDSADPSPVHKDG 123
E R+ N E A P P + A+ + P+ ++G
Sbjct: 443 ENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENG 502
Query: 124 QNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQF 183
Q + + S T N +P + ++++ + ++ PSP +
Sbjct: 503 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTE- 561
Query: 184 MMPRSSSRCSCGDGKEPQTITQLTKHIQSL----KRKIRKFEEKFEQEKKY-------RP 232
+ R + K ++ + T++ Q ++ E E E++ P
Sbjct: 562 ----NGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTP 617
Query: 233 SHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNL-------LCEQPT 285
S + T N E N + ++ +E+ P P N P
Sbjct: 618 SPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPA 677
Query: 286 VPRENG--------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNL 337
P ENG K ++ EP+ GE TP A E +E + K
Sbjct: 678 EPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFP 737
Query: 338 IKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSN 397
+P +R R + +TPS P E PSLA+P + G ++N
Sbjct: 738 AEPTENRERTANE-NTTPS--PAQPTENGDRTPLANEKTTPSLAEPTEN---GKRTPFAN 791
Query: 398 ETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKK 443
E + P E E P ++N + + P RE A++K
Sbjct: 792 EKTTSSSAEPTEHAERTP----LANENTTSSPAEPTENRERTANEK 833
Score = 30.4 bits (67), Expect = 3.9
Identities = 81/429 (18%), Positives = 145/429 (33%), Gaps = 53/429 (12%)
Query: 11 SIFKAESGRSHGESQETEHVVSSQSECQVRAGTP-AHESPQNNAFKCQETVRLQPRIDQR 69
++F AE + + + S + TP A+E +++ + E P ++
Sbjct: 654 TLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANEN 713
Query: 70 TAISPKDAFETRQDLNEEEAAQVHGVKDPAPAS-TQSVLADGTDSADPSPVHKDGQNEAD 128
T +SP + E R+ E+ P PA T++ ++ PSP D
Sbjct: 714 TTLSPAEPTENRERTANEKTT-------PFPAEPTENRERTANENTTPSPAQPT--ENGD 764
Query: 129 SAPEDLHSVGTSRLLYHITDGDN--PLLSPRCSIFS-----QSQRFNLDPESAPSPPSTQ 181
P L + T+ L T+ P + + + S ++R L E+ S P+
Sbjct: 765 RTP--LANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEP 822
Query: 182 QFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNP 241
R+++ + EP + T + K F + + +++ + S
Sbjct: 823 TENRERTANEKTTQFPAEPTENRESTAN-----EKTTPFPAEPTENREWTANENTTLSPA 877
Query: 242 EVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPS 301
E + +E+ +E+ +P P N P N K + EP+
Sbjct: 878 EPTEH-----------EEMTPLANEKTTLSPAEPTEN----GERTPFTNEKTTPSSAEPT 922
Query: 302 SSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTI 361
GE TP A R E E K + KP + + + S PT
Sbjct: 923 EHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTE 982
Query: 362 QEEE-------------DSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPD 408
E +S E + + + + PA G+ +NE P
Sbjct: 983 NGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPT 1042
Query: 409 EKKEVKPPA 417
E +E+ P A
Sbjct: 1043 EHEEMTPSA 1051
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.5 bits (88), Expect = 0.014
Identities = 65/281 (23%), Positives = 111/281 (39%), Gaps = 39/281 (13%)
Query: 208 KHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLK---ELKLKL 264
K ++ L+ K RK EE+ EQEK+ R +K + K L K +++ + E LKL
Sbjct: 367 KRLEELEAK-RKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425
Query: 265 SEEQG-------SAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKE 317
+ QG S PK P ++ +P++ E + + E + + +E
Sbjct: 426 LQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEE 485
Query: 318 RREQLPPQE----------DSKVTKQDKNLIKPLYDRYRI-IKQILSTPSLIPTIQEEED 366
+ P+E D + D+ K ++ I +K+ P +EEE+
Sbjct: 486 TPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKE-------NPEEEEEEE 538
Query: 367 SDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEA 426
+E+ + S++ + S GD E E V K K P+ MS+ E
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGD-----EEDEKVSDEKDSGKTLDKKPSKEMSSDSEY 593
Query: 427 TMPVLLDHLRETRA---DKKRLRKALREFEEQFFKQTGRSP 464
D +E RA K+R+ K E + + R+P
Sbjct: 594 DSDD--DRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAP 632
Score = 29.6 bits (65), Expect = 6.7
Identities = 28/128 (21%), Positives = 52/128 (40%), Gaps = 9/128 (7%)
Query: 214 KRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPK 273
K K+RK +EK E E + K S K+ + K + + + SEE+ P
Sbjct: 247 KAKLRKLKEKEELETGKKDQSKQKESQR---KFEEETVKSKVTVDTGVIPASEEKAETPT 303
Query: 274 GPPRNLLCEQPTVPRENGKPEAAGPE------PSSSGEETPDAALTCLKERREQLPPQED 327
+ ++ ++ K E E PS + + AL LKE E+ +E+
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363
Query: 328 SKVTKQDK 335
++ + ++
Sbjct: 364 ERIKRLEE 371
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 38.1 bits (87), Expect = 0.019
Identities = 58/234 (24%), Positives = 92/234 (39%), Gaps = 38/234 (16%)
Query: 96 KDPAPASTQSVLADGTDSADPSPVH-KDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLL 154
K PA +S+ ++ G S S + KD ++ P TS+L D PL
Sbjct: 2234 KPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQHSGRPSPGCDSQTSQL-------DQPLF 2286
Query: 155 ------SPRCSIFSQSQRFNLDPES-----APSPPSTQQFMMPRSSSRCSCGDGKEPQTI 203
SP + S+S R N+ P S A S PS S+R S D + +
Sbjct: 2287 KLKYPSSPYSAHISKSPR-NMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKL 2345
Query: 204 TQ--LTKHIQSLKRKIRKFEEKFEQE-----KKYRPSHGDKTSNPEVLKWMN------DL 250
+ + +Q++ ++ F + Q K +R + G TS +VL +N
Sbjct: 2346 KMAAIDEKVQAV-HNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLSLLNLSPRHNKK 2404
Query: 251 AKGRKQLKELKLKLSEEQGSAPKGPP----RNLLCEQPTVPRENGKPEAAGPEP 300
+G +L+ +L L + G+ PK PP R ++P G P A P
Sbjct: 2405 EEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPLPAGPPATAPARP 2458
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 38.1 bits (87), Expect = 0.019
Identities = 52/236 (22%), Positives = 84/236 (35%), Gaps = 45/236 (19%)
Query: 282 EQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPL 341
E P+ E PEA P+P SS E + C R + P Q + K +P
Sbjct: 522 EDPSSQEEAHTPEAPPPQPPSS--ERCLGEMKCTLVRGDSSPRQAELKSGPAS----RPA 575
Query: 342 YDRYRIIKQILSTPSLIP-----TIQEEEDSDEDRP--------QGSQQPSLADPASHLP 388
++ ++ + P P T +EE +E RP +G LP
Sbjct: 576 LEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP 635
Query: 389 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDH-----------LRE 437
+ + E P+ + + +KPP S L +P L+ +
Sbjct: 636 PKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETL---ALPSLVPQNYTENKNEGVDVTS 692
Query: 438 TRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLI 493
R + + LR+AL E Q ++ + D + E K K + R LEV +
Sbjct: 693 LRGEVESLRRALELMEVQLERK------------LTDIWEELKSEKEQRRRLEVQV 736
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 38.1 bits (87), Expect = 0.019
Identities = 52/236 (22%), Positives = 84/236 (35%), Gaps = 45/236 (19%)
Query: 282 EQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPL 341
E P+ E PEA P+P SS E + C R + P Q + K +P
Sbjct: 411 EDPSSQEEAHTPEAPPPQPPSS--ERCLGEMKCTLVRGDSSPRQAELKSGPAS----RPA 464
Query: 342 YDRYRIIKQILSTPSLIP-----TIQEEEDSDEDRP--------QGSQQPSLADPASHLP 388
++ ++ + P P T +EE +E RP +G LP
Sbjct: 465 LEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELP 524
Query: 389 VGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDH-----------LRE 437
+ + E P+ + + +KPP S L +P L+ +
Sbjct: 525 PKEEVAPKEEVPPIERAFAQKTRPIKPPPDSQETL---ALPSLVPQNYTENKNEGVDVTS 581
Query: 438 TRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLI 493
R + + LR+AL E Q ++ + D + E K K + R LEV +
Sbjct: 582 LRGEVESLRRALELMEVQLERK------------LTDIWEELKSEKEQRRRLEVQV 625
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 37.7 bits (86), Expect = 0.025
Identities = 94/471 (19%), Positives = 163/471 (34%), Gaps = 68/471 (14%)
Query: 21 HGESQETEHVVSSQSE-CQVRAGTP-AHESPQNNAFKCQETVRLQPRIDQRTAISPKDAF 78
HGE E+ S +E + TP A++ +++ + E P ++ T SP +
Sbjct: 445 HGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPT 504
Query: 79 ETRQDL--------------NEEEAAQVHGVKDPA-PASTQSVLADGTDSADPSPVHKDG 123
E R+ N E A P P + A+ + P+ ++G
Sbjct: 505 ENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENG 564
Query: 124 QNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQF 183
Q + + S T N +P + ++++ + ++ PSP +
Sbjct: 565 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTE- 623
Query: 184 MMPRSSSRCSCGDGKEPQTITQLTKHIQSL----KRKIRKFEEKFEQEKKY-------RP 232
+ R + K ++ + T++ Q ++ E E E++ P
Sbjct: 624 ----NGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTP 679
Query: 233 SHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNL-------LCEQPT 285
S + T N E N + ++ +E+ P P N P
Sbjct: 680 SPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPA 739
Query: 286 VPRENG--------KPEAAGPEPSSSGEETPDAALTCLKERREQLP--PQEDSKVTKQDK 335
P ENG K ++ EP+ GE TP A E P P E+ + T +K
Sbjct: 740 EPTENGQRTPFANEKTTSSSAEPTEHGERTPLA-----NENTTLSPAGPTENRERTANEK 794
Query: 336 NL---IKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDH 392
+P +R R + +TPS P E PSLA+P + G
Sbjct: 795 TTPFPAEPTENRERTANE-NTTPS--PAQPTENGDRTPLANEKTTPSLAEPTEN---GKR 848
Query: 393 LTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKK 443
++NE + P E E P ++N + + P RE A++K
Sbjct: 849 TPFANEKTTSSSAEPTEHAERTP----LANENTTSSPAEPTENRERTANEK 895
>gi|151101151 coiled-coil domain containing 2 isoform b [Homo
sapiens]
Length = 372
Score = 37.7 bits (86), Expect = 0.025
Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 31/171 (18%)
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E Q++ + Q+ +++IR EE+ EQEK+ + +++K M+ Q+
Sbjct: 182 RETQSLDVIFTERQAKEKQIRSVEEEIEQEKQ---------ATDDIIKNMS----FENQV 228
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCEQPTVPR----ENGKPEAAGPEPSSSGEETPDAALT 313
K L++K + E+ LL E T+ + +N K E+ E + S + +A L
Sbjct: 229 KYLEMKTTNEK----------LLQELDTLQQQLDSQNMKKESLEAEIAHS-QVKQEAVL- 276
Query: 314 CLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEE 364
L E+ +L D + +DK++ P+ +R +++KQI I +++ +
Sbjct: 277 -LHEKLYELESHRDQMIA-EDKSIGSPMEEREKLLKQIKDDNQEIASMERQ 325
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 37.7 bits (86), Expect = 0.025
Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 31/171 (18%)
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E Q++ + Q+ +++IR EE+ EQEK+ + +++K M+ Q+
Sbjct: 182 RETQSLDVIFTERQAKEKQIRSVEEEIEQEKQ---------ATDDIIKNMS----FENQV 228
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCEQPTVPR----ENGKPEAAGPEPSSSGEETPDAALT 313
K L++K + E+ LL E T+ + +N K E+ E + S + +A L
Sbjct: 229 KYLEMKTTNEK----------LLQELDTLQQQLDSQNMKKESLEAEIAHS-QVKQEAVL- 276
Query: 314 CLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEE 364
L E+ +L D + +DK++ P+ +R +++KQI I +++ +
Sbjct: 277 -LHEKLYELESHRDQMIA-EDKSIGSPMEEREKLLKQIKDDNQEIASMERQ 325
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 37.7 bits (86), Expect = 0.025
Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 31/171 (18%)
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E Q++ + Q+ +++IR EE+ EQEK+ + +++K M+ Q+
Sbjct: 182 RETQSLDVIFTERQAKEKQIRSVEEEIEQEKQ---------ATDDIIKNMS----FENQV 228
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCEQPTVPR----ENGKPEAAGPEPSSSGEETPDAALT 313
K L++K + E+ LL E T+ + +N K E+ E + S + +A L
Sbjct: 229 KYLEMKTTNEK----------LLQELDTLQQQLDSQNMKKESLEAEIAHS-QVKQEAVL- 276
Query: 314 CLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEE 364
L E+ +L D + +DK++ P+ +R +++KQI I +++ +
Sbjct: 277 -LHEKLYELESHRDQMIA-EDKSIGSPMEEREKLLKQIKDDNQEIASMERQ 325
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 37.7 bits (86), Expect = 0.025
Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 31/171 (18%)
Query: 198 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQL 257
+E Q++ + Q+ +++IR EE+ EQEK+ + +++K M+ Q+
Sbjct: 182 RETQSLDVIFTERQAKEKQIRSVEEEIEQEKQ---------ATDDIIKNMS----FENQV 228
Query: 258 KELKLKLSEEQGSAPKGPPRNLLCEQPTVPR----ENGKPEAAGPEPSSSGEETPDAALT 313
K L++K + E+ LL E T+ + +N K E+ E + S + +A L
Sbjct: 229 KYLEMKTTNEK----------LLQELDTLQQQLDSQNMKKESLEAEIAHS-QVKQEAVL- 276
Query: 314 CLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEE 364
L E+ +L D + +DK++ P+ +R +++KQI I +++ +
Sbjct: 277 -LHEKLYELESHRDQMIA-EDKSIGSPMEEREKLLKQIKDDNQEIASMERQ 325
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 37.0 bits (84), Expect = 0.042
Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 27/243 (11%)
Query: 201 QTITQLTKHIQSLKRKIRKFEEKFEQEKK-YRPSHGDKTSNPEVLKWMNDLAKGRKQLKE 259
+ IT+LT I+ KR+ + E++F+Q+K Y + E L W + K +KE
Sbjct: 1109 EKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQK--LESEKAIKE 1166
Query: 260 LKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERR 319
+ ++ R LL E+ T RE A + S+ +E+ + ++ER
Sbjct: 1167 KEYEIER---------LRVLLQEEGTRKREYENELA---KASNRIQESKNQCTQVVQERE 1214
Query: 320 EQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQ--EEEDSDEDRPQGSQQ 377
L KV +QDK ++ L D K L + + E++ D Q Q
Sbjct: 1215 SLL---VKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQ 1271
Query: 378 PSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRE 437
S + A + E +R+ + + E+K + E L D RE
Sbjct: 1272 YSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIK-------RIEERCRRKLEDSTRE 1324
Query: 438 TRA 440
T++
Sbjct: 1325 TQS 1327
>gi|169214011 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 37.0 bits (84), Expect = 0.042
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 4/43 (9%)
Query: 269 GSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAA 311
G+ P+ PP L PT+P ++GK EA GPEP ETP AA
Sbjct: 141 GAGPRTPPMTLP-SPPTLPAQDGKKEARGPEPPL---ETPLAA 179
>gi|113428768 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 37.0 bits (84), Expect = 0.042
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 4/43 (9%)
Query: 269 GSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAA 311
G+ P+ PP L PT+P ++GK EA GPEP ETP AA
Sbjct: 141 GAGPRTPPMTLP-SPPTLPAQDGKKEARGPEPPL---ETPLAA 179
>gi|113428351 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 37.0 bits (84), Expect = 0.042
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 4/43 (9%)
Query: 269 GSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAA 311
G+ P+ PP L PT+P ++GK EA GPEP ETP AA
Sbjct: 141 GAGPRTPPMTLP-SPPTLPAQDGKKEARGPEPPL---ETPLAA 179
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 37.0 bits (84), Expect = 0.042
Identities = 57/268 (21%), Positives = 101/268 (37%), Gaps = 19/268 (7%)
Query: 161 FSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKF 220
FS+S+ + + S S + + +SS + + E Q T + I F
Sbjct: 159 FSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSF 218
Query: 221 EEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKL-SEEQGSAPKGPPRNL 279
+ + KK P + EV + K++ +++ S E+ A PP
Sbjct: 219 TQ---ETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPP--- 272
Query: 280 LCEQPTVPRENGKPEAAGPEPSSSGEETPDA-ALTCLKER--REQLPPQEDSKVTKQDKN 336
L E+ T E E + S EETPDA A T + E + Q PP E++ + +
Sbjct: 273 LVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAE 332
Query: 337 LIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHL------PVG 390
+ P + ++ + ++P EE S+E + P+ P+ L P
Sbjct: 333 IQPPSAEESPSVELL---AEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA 389
Query: 391 DHLTYSNETEPVRALLPDEKKEVKPPAL 418
+ P L + +V+PP +
Sbjct: 390 QKAPIEVQPLPAEGALEEAPAKVEPPTV 417
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 36.6 bits (83), Expect = 0.055
Identities = 57/229 (24%), Positives = 86/229 (37%), Gaps = 47/229 (20%)
Query: 97 DPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSP 156
D AP + A G + P + G+ +A+ A + +RL Y+ P P
Sbjct: 828 DEAPVPPEDEAAAGAEDEPP----RTGELKAEGATAE----AGARLPYY------PAYVP 873
Query: 157 RCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRK 216
R L P P P + M R E T+ +LT+ + K K
Sbjct: 874 R----------TLKPTVPPLTPEQYELYMYR-----------EVDTL-ELTRQV---KEK 908
Query: 217 IRK--FEEKFEQEKKYRPSHG---DKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSA 271
+ K ++ EK S G D S P+ W KGR+ ++L LS++ G A
Sbjct: 909 LAKNGICQRIFGEKVLGLSQGSVSDMLSRPK--PWSKLTQKGREPFIRMQLWLSDQLGQA 966
Query: 272 PKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERRE 320
P PT PR + P + EP S +E +L KE ++
Sbjct: 967 VGQQP-GASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLESSKENQQ 1014
Score = 29.3 bits (64), Expect = 8.7
Identities = 35/150 (23%), Positives = 56/150 (37%), Gaps = 29/150 (19%)
Query: 243 VLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSS 302
V+ W ++ + R + + L +E P G P L P + P+ P P S
Sbjct: 1212 VINWFHNY-RSRMRREMLVEGTQDEPDLDPSGGPGIL-------PPGHSHPD---PTPQS 1260
Query: 303 SGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQ 362
ET D T + ++ P + + +T QDK ++ IKQ Q
Sbjct: 1261 PDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVR--------IKQ----------EQ 1302
Query: 363 EEEDSDEDRPQGSQQPSLADPASHLPVGDH 392
EED++E+ Q D P +H
Sbjct: 1303 MEEDAEEEAGSQPQDSGELDKGQGPPKEEH 1332
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,865,351
Number of Sequences: 37866
Number of extensions: 1262491
Number of successful extensions: 5798
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 5454
Number of HSP's gapped (non-prelim): 584
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.