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Search of human proteins with 218505827
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218505827 TRAF4 associated factor 1 isoform a [Homo sapiens]
(316 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218505827 TRAF4 associated factor 1 isoform a [Homo sapiens] 620 e-178
gi|218505831 TRAF4 associated factor 1 isoform b [Homo sapiens] 540 e-154
gi|218505833 TRAF4 associated factor 1 isoform c [Homo sapiens] 455 e-128
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 51 1e-06
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 50 3e-06
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 48 1e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 47 2e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 47 2e-05
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 47 2e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 47 3e-05
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 47 3e-05
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 47 3e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 45 6e-05
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 45 8e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 45 8e-05
gi|171906567 peripheral benzodiazepine receptor-associated prote... 45 1e-04
gi|171906559 peripheral benzodiazepine receptor-associated prote... 45 1e-04
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 44 1e-04
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 44 1e-04
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 44 1e-04
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 44 1e-04
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2... 44 1e-04
gi|50980307 myosin phosphatase-Rho interacting protein isoform 1... 44 1e-04
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 43 3e-04
gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sa... 43 3e-04
gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s... 43 3e-04
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s... 43 3e-04
gi|4758646 kinesin family member 3B [Homo sapiens] 43 4e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 43 4e-04
gi|33946313 ninein isoform 4 [Homo sapiens] 43 4e-04
>gi|218505827 TRAF4 associated factor 1 isoform a [Homo sapiens]
Length = 316
Score = 620 bits (1598), Expect = e-178
Identities = 316/316 (100%), Positives = 316/316 (100%)
Query: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK
Sbjct: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
Query: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV
Sbjct: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
Query: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ
Sbjct: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
Query: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE 240
LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE
Sbjct: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE 240
Query: 241 STTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQV 300
STTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQV
Sbjct: 241 STTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQV 300
Query: 301 NDLTTALKEMEQLLEM 316
NDLTTALKEMEQLLEM
Sbjct: 301 NDLTTALKEMEQLLEM 316
>gi|218505831 TRAF4 associated factor 1 isoform b [Homo sapiens]
Length = 286
Score = 540 bits (1392), Expect = e-154
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK
Sbjct: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
Query: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV
Sbjct: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
Query: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ
Sbjct: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
Query: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE 240
LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE
Sbjct: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQE 240
Query: 241 STTDHMDSMLLLETLQEELKLFNETAKKQMEELQ 274
STTDHMDSMLLLETLQEELKLFNETAKKQMEELQ
Sbjct: 241 STTDHMDSMLLLETLQEELKLFNETAKKQMEELQ 274
>gi|218505833 TRAF4 associated factor 1 isoform c [Homo sapiens]
Length = 241
Score = 455 bits (1170), Expect = e-128
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK
Sbjct: 1 MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
Query: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV
Sbjct: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
Query: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ
Sbjct: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQ 180
Query: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDP 228
LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDP
Sbjct: 181 LLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDP 228
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 51.2 bits (121), Expect = 1e-06
Identities = 67/255 (26%), Positives = 112/255 (43%), Gaps = 33/255 (12%)
Query: 84 KTVYSLQPPSALSGGQPADTQTRATSKSLLPV---RSKEVDVSKQLHS---GGPENDVTK 137
K V Q S +G P A K + + RS+ ++V+KQ + K
Sbjct: 275 KAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQK 334
Query: 138 ITKLRRENG--QMKATDT-ATRRNVRKGYKP---LSKQKSEEELKDKNQLLEAVNKQLHQ 191
IT+LR++ Q + TD A R ++ + L+K K E E DK QL A K+L Q
Sbjct: 335 ITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLT-AEAKELRQ 393
Query: 192 KLTETQGELKDLT-------QKVELLEKFRDNCLAILESKGLDPAL-----GSETLASRQ 239
K+ Q +L LT ++++ L K + L+I P G+ L +Q
Sbjct: 394 KVKYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQ 453
Query: 240 ESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQAL-KVKLEMKEERVRFLEQQTLCNN 298
E T + E L++++K+F E +++ + + + + K E+K++ + Q TL N
Sbjct: 454 ELVTQN-------ELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNA 506
Query: 299 QVNDLTTALKEMEQL 313
Q+ K E L
Sbjct: 507 QLKAFKDEEKAREAL 521
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 50.1 bits (118), Expect = 3e-06
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 20/217 (9%)
Query: 97 GGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTK--ITKLRRENGQMKATDTA 154
G + + T TS++L +R + S Q+ E K + K++ + Q K A
Sbjct: 795 GARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEA 854
Query: 155 TRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFR 214
RR+ SK + ELK + L++ K+L Q+L + GE + T + EL R
Sbjct: 855 YRRDAT------SKDQLISELKATRKRLDSELKELRQELMQVHGEKR--TAEAELSRLHR 906
Query: 215 DNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQ 274
+ L+ L ++ ++ H+ S+ + + NE KKQ+EELQ
Sbjct: 907 EVAQVRQHMADLEGHL--QSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQ 964
Query: 275 ALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEME 311
+E R EQ+ +DLT+A KEM+
Sbjct: 965 --------QEARKAITEQKQKMRRLGSDLTSAQKEMK 993
Score = 36.6 bits (83), Expect = 0.030
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
Query: 167 SKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKD---LTQKVELLEKFRDNCLAILE- 222
SK E+EL++ L ++ +K+ E + EL++ +K++ LE+ LE
Sbjct: 1057 SKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEH 1116
Query: 223 SKGLDPALGSETLASRQ-----ESTTDHMDSMLLLETLQEELKLFN-ETAKKQMEEL-QA 275
KG LG A R+ E+ ++ L+ LQ + L E +QM+ L QA
Sbjct: 1117 EKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQA 1176
Query: 276 LKVKLEMKEERVRFLEQQ 293
L+ LE ++E+V L++Q
Sbjct: 1177 LQASLEKEKEKVNSLKEQ 1194
Score = 29.3 bits (64), Expect = 4.8
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Query: 189 LHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDS 248
LH+++ + EL+ ++ LLEK + AL S+ L +E + D
Sbjct: 1040 LHERIQALEAELQAVSHSKTLLEKELQEVI----------ALTSQELEESREKVLELEDE 1089
Query: 249 MLLLETLQEELKLFNETAKKQMEELQALKVKL 280
+ ++++K E+ KK EL+ K KL
Sbjct: 1090 LQESRGFRKKIKRLEESNKKLALELEHEKGKL 1121
Score = 28.5 bits (62), Expect = 8.2
Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 21/170 (12%)
Query: 140 KLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKN----QLLEA---VNKQLHQK 192
KL + + T+T R KG Q E ++ D+ Q+ EA V + L ++
Sbjct: 614 KLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRR 673
Query: 193 LTETQGELKDLTQKVELLEKFRDNCLAI---LESKGLDPALGSETLASRQESTTDHMDSM 249
L E +GE E L++ D+ ++ LE L + L + Q+ D M +
Sbjct: 674 LEEFEGER-------ERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQL 726
Query: 250 LLLETLQEELKLFNETAKKQMEELQA----LKVKLEMKEERVRFLEQQTL 295
L + + + + + +ELQA L+ + +E+ + L+ + +
Sbjct: 727 TLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKI 776
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 48.1 bits (113), Expect = 1e-05
Identities = 68/325 (20%), Positives = 133/325 (40%), Gaps = 18/325 (5%)
Query: 3 APEAPP--LDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEK 60
+PE P +V + T + LP ++ L + +AG L +
Sbjct: 105 SPETPDSSASKVLKREGTDTTAKTSKLPTRPASTGVAGASSSLGPSGSASAGELSSSEPS 164
Query: 61 DCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEV 120
Q A + P ++T V + S PS G A Q R + L +R K
Sbjct: 165 TPAQTPLAAPIIPTPVLTSPGAVPPLPS---PSKEEEGLRA--QVRDLEEKLETLRLKRA 219
Query: 121 DVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPL-----SKQKSEEEL 175
+ +L E ++ +++ +M+ +R +++ K +K++ EE+
Sbjct: 220 EDKAKLKE--LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEM 277
Query: 176 KDKNQLLE--AVNKQLHQKLTET-QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGS 232
D +E ++K++ ++ E+ Q E++ L ++V+ L + A +E KG D A S
Sbjct: 278 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 337
Query: 233 ETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEEL-QALKVKLEMKEERVRFLE 291
L +E D+++ + L K + +K ME+ Q L+V + +E L
Sbjct: 338 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 397
Query: 292 QQTLCNNQVNDLTTALKEMEQLLEM 316
Q +++ + A E+++EM
Sbjct: 398 QAESTIDELKEQVDAALGAEEMVEM 422
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/163 (26%), Positives = 82/163 (50%), Gaps = 21/163 (12%)
Query: 132 ENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQ 191
+N ++ L +EN Q+ + RRNV + K S + ++ +L++K LE+ +QL +
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNV-ESLKCASMKMAQLQLENKE--LESEKEQLKK 739
Query: 192 KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLL 251
L + K K E LE + +GLD + ++ L E++ +
Sbjct: 740 GLELLKASFK----KTERLE---------VSYQGLD--IENQRLQKTLENSNKKIQQ--- 781
Query: 252 LETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQT 294
LE+ ++L++ N+T +K +EEL+ +LE E+ + LEQ+T
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Score = 45.1 bits (105), Expect = 8e-05
Identities = 54/212 (25%), Positives = 93/212 (43%), Gaps = 19/212 (8%)
Query: 116 RSKEVDVSKQLHSGGPENDVT--KITKLRRENGQMKATDTATRRNVRK----GYKPLSKQ 169
R+ E+ + Q G N++T ++ KL EN + T R V K L +
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 170 KSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEK----FRDNC---LAILE 222
K + L K ++LE Q Q L Q KDL ++ LEK R+N + ILE
Sbjct: 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Query: 223 SKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKV-KLE 281
+ + L + RQ S + + ++ +++E K+ +E+ K+ +L ++ K +
Sbjct: 558 QE--NEHLNQTVSSLRQRS---QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ 612
Query: 282 MKEERVRFLEQQTLCNNQVNDLTTALKEMEQL 313
+K+E + E+ N+L KE E L
Sbjct: 613 IKKELEHYKEKGERAEELENELHHLEKENELL 644
Score = 38.1 bits (87), Expect = 0.010
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 34/206 (16%)
Query: 113 LPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVR------------ 160
L V + +D+ Q EN KI +L E ++ + ++N+
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Query: 161 -KGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEK------- 212
K K L ++ S+ E KDK QL E NK+L Q+ L++ K+ LEK
Sbjct: 814 EKENKSLEQETSQLE-KDKKQL-EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 213 ----FRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKK 268
++++C+ + E L E + +T D + L E L E KL +
Sbjct: 872 EIGIYKESCVRLKE-------LEKENKELVKRATIDIKTLVTLREDLVSE-KLKTQQMNN 923
Query: 269 QMEELQALKVKLEMKEERVRFLEQQT 294
+E+L K+ + +ER+ EQ T
Sbjct: 924 DLEKLTHELEKIGLNKERLLHDEQST 949
Score = 32.0 bits (71), Expect = 0.74
Identities = 30/150 (20%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 144 ENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDL 203
+N + + TR ++ + + +++ L+ + Q L+ KQL + Q ++ L
Sbjct: 1027 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL 1086
Query: 204 TQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFN 263
++ L++ L+++ + + TL S Q ++ + ++ LL++ Q L+ N
Sbjct: 1087 QRQTVSLQEQNTT----LQTQNAKLQVENSTLNS-QSTSLMNQNAQLLIQ--QSSLENEN 1139
Query: 264 ETAKKQMEELQALKVKLEMKEERVRFLEQQ 293
E+ K+ E+L++L L E++ L ++
Sbjct: 1140 ESVIKEREDLKSLYDSLIKDHEKLELLHER 1169
Score = 32.0 bits (71), Expect = 0.74
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 116 RSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSE--- 172
R E ++ L G D+ K+ K+ +E ++ + T V YK L +
Sbjct: 1196 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHET---VAAEYKKLCGENDRLNH 1252
Query: 173 --EELKDKNQLLEAVNKQL-----HQKLTETQGE-----LKDLTQKVELLE-KFRDNCLA 219
+L + ++L+ +K L + KL +T+ E LK+ Q++++ K + C
Sbjct: 1253 TYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL 1312
Query: 220 ILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVK 279
+ + KG L E + T + + LLE E LF+ ++ +++L L+ +
Sbjct: 1313 LSQLKG---NLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQ 1369
Query: 280 LEMKEERV 287
E EE++
Sbjct: 1370 KEKLEEKI 1377
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/163 (26%), Positives = 82/163 (50%), Gaps = 21/163 (12%)
Query: 132 ENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQ 191
+N ++ L +EN Q+ + RRNV + K S + ++ +L++K LE+ +QL +
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNV-ESLKCASMKMAQLQLENKE--LESEKEQLKK 739
Query: 192 KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLL 251
L + K K E LE + +GLD + ++ L E++ +
Sbjct: 740 GLELLKASFK----KTERLE---------VSYQGLD--IENQRLQKTLENSNKKIQQ--- 781
Query: 252 LETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQT 294
LE+ ++L++ N+T +K +EEL+ +LE E+ + LEQ+T
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Score = 45.1 bits (105), Expect = 8e-05
Identities = 54/212 (25%), Positives = 93/212 (43%), Gaps = 19/212 (8%)
Query: 116 RSKEVDVSKQLHSGGPENDVT--KITKLRRENGQMKATDTATRRNVRK----GYKPLSKQ 169
R+ E+ + Q G N++T ++ KL EN + T R V K L +
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 170 KSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEK----FRDNC---LAILE 222
K + L K ++LE Q Q L Q KDL ++ LEK R+N + ILE
Sbjct: 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Query: 223 SKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKV-KLE 281
+ + L + RQ S + + ++ +++E K+ +E+ K+ +L ++ K +
Sbjct: 558 QE--NEHLNQTVSSLRQRS---QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQ 612
Query: 282 MKEERVRFLEQQTLCNNQVNDLTTALKEMEQL 313
+K+E + E+ N+L KE E L
Sbjct: 613 IKKELEHYKEKGERAEELENELHHLEKENELL 644
Score = 38.1 bits (87), Expect = 0.010
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 34/206 (16%)
Query: 113 LPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVR------------ 160
L V + +D+ Q EN KI +L E ++ + ++N+
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Query: 161 -KGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEK------- 212
K K L ++ S+ E KDK QL E NK+L Q+ L++ K+ LEK
Sbjct: 814 EKENKSLEQETSQLE-KDKKQL-EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 213 ----FRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKK 268
++++C+ + E L E + +T D + L E L E KL +
Sbjct: 872 EIGIYKESCVRLKE-------LEKENKELVKRATIDIKTLVTLREDLVSE-KLKTQQMNN 923
Query: 269 QMEELQALKVKLEMKEERVRFLEQQT 294
+E+L K+ + +ER+ EQ T
Sbjct: 924 DLEKLTHELEKIGLNKERLLHDEQST 949
Score = 32.0 bits (71), Expect = 0.74
Identities = 30/150 (20%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 144 ENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDL 203
+N + + TR ++ + + +++ L+ + Q L+ KQL + Q ++ L
Sbjct: 1026 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL 1085
Query: 204 TQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFN 263
++ L++ L+++ + + TL S Q ++ + ++ LL++ Q L+ N
Sbjct: 1086 QRQTVSLQEQNTT----LQTQNAKLQVENSTLNS-QSTSLMNQNAQLLIQ--QSSLENEN 1138
Query: 264 ETAKKQMEELQALKVKLEMKEERVRFLEQQ 293
E+ K+ E+L++L L E++ L ++
Sbjct: 1139 ESVIKEREDLKSLYDSLIKDHEKLELLHER 1168
Score = 32.0 bits (71), Expect = 0.74
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 116 RSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSE--- 172
R E ++ L G D+ K+ K+ +E ++ + T V YK L +
Sbjct: 1195 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHET---VAAEYKKLCGENDRLNH 1251
Query: 173 --EELKDKNQLLEAVNKQL-----HQKLTETQGE-----LKDLTQKVELLE-KFRDNCLA 219
+L + ++L+ +K L + KL +T+ E LK+ Q++++ K + C
Sbjct: 1252 TYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL 1311
Query: 220 ILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVK 279
+ + KG L E + T + + LLE E LF+ ++ +++L L+ +
Sbjct: 1312 LSQLKG---NLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQ 1368
Query: 280 LEMKEERV 287
E EE++
Sbjct: 1369 KEKLEEKI 1376
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/207 (20%), Positives = 94/207 (45%), Gaps = 14/207 (6%)
Query: 110 KSLLPVRSKEVDVSKQLHSGG-----PENDVTKITKLRRENGQMKATDTATRRNVRKGYK 164
+++L ++ + V+++K + G +++ + + + E + + + +R+
Sbjct: 118 ETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLA 177
Query: 165 PLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESK 224
++Q+ E E + K + A++ Q Q++ + Q E +K E LEK A ++S+
Sbjct: 178 QTTEQQQETE-RSKEEAEHAIS-QFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235
Query: 225 GLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKE 284
+ + + Q+ + + LE +E K+ NE A K++E+ Q KL+ +
Sbjct: 236 QTE-------IKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQEN 288
Query: 285 ERVRFLEQQTLCNNQVNDLTTALKEME 311
E+ + +Q NQ L KE E
Sbjct: 289 EQHSLVCEQLSQENQQKALELKAKEEE 315
Score = 33.5 bits (75), Expect = 0.25
Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDK---NQLLEAVNKQLHQKL 193
+I KLRRE G + A A +R+ + + ++ +E + + +L +N +KL
Sbjct: 658 EIKKLRREKGIL-ARSMANVEELRQEFFHMQRELLKERTRCRALEEELENPLNVHRWRKL 716
Query: 194 TETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLE 253
+ +L QK+ L+K L SK + + E L +E + +L +
Sbjct: 717 EASDPNAYELIQKIHTLQKR-------LISK-TEEVVEKELLLQEKEKLYMELKHVLARQ 768
Query: 254 T---LQEELKLFNETAKKQMEELQALKVKLEMKE 284
E+LKL+ T + ++L+ L +L M E
Sbjct: 769 PGPEAAEQLKLYRRTLHDKKQQLKVLSSELNMYE 802
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 46.6 bits (109), Expect = 3e-05
Identities = 61/286 (21%), Positives = 122/286 (42%), Gaps = 16/286 (5%)
Query: 40 AADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQ 99
++ L + +AG L + Q A + P ++T V + S PS G
Sbjct: 30 SSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPS---PSKEEEGL 86
Query: 100 PADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNV 159
A Q R + L +R K + +L E ++ +++ +M+ +R +
Sbjct: 87 RA--QVRDLEEKLETLRLKRAEDKAKLKE--LEKHKIQLEQVQEWKSKMQEQQADLQRRL 142
Query: 160 RKGYKPL-----SKQKSEEELKDKNQLLE--AVNKQLHQKLTET-QGELKDLTQKVELLE 211
++ K +K++ EE+ D +E ++K++ ++ E+ Q E++ L ++V+ L
Sbjct: 143 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 202
Query: 212 KFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQME 271
+ A +E KG D A S L +E D+++ + L K + +K ME
Sbjct: 203 TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLME 262
Query: 272 EL-QALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM 316
+ Q L+V + +E L Q +++ + A E+++EM
Sbjct: 263 KKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 308
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 46.6 bits (109), Expect = 3e-05
Identities = 61/286 (21%), Positives = 122/286 (42%), Gaps = 16/286 (5%)
Query: 40 AADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQ 99
++ L + +AG L + Q A + P ++T V + S PS G
Sbjct: 30 SSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPS---PSKEEEGL 86
Query: 100 PADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNV 159
A Q R + L +R K + +L E ++ +++ +M+ +R +
Sbjct: 87 RA--QVRDLEEKLETLRLKRAEDKAKLKE--LEKHKIQLEQVQEWKSKMQEQQADLQRRL 142
Query: 160 RKGYKPL-----SKQKSEEELKDKNQLLE--AVNKQLHQKLTET-QGELKDLTQKVELLE 211
++ K +K++ EE+ D +E ++K++ ++ E+ Q E++ L ++V+ L
Sbjct: 143 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 202
Query: 212 KFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQME 271
+ A +E KG D A S L +E D+++ + L K + +K ME
Sbjct: 203 TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLME 262
Query: 272 EL-QALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM 316
+ Q L+V + +E L Q +++ + A E+++EM
Sbjct: 263 KKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 308
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 46.6 bits (109), Expect = 3e-05
Identities = 61/286 (21%), Positives = 122/286 (42%), Gaps = 16/286 (5%)
Query: 40 AADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQ 99
++ L + +AG L + Q A + P ++T V + S PS G
Sbjct: 164 SSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPS---PSKEEEGL 220
Query: 100 PADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNV 159
A Q R + L +R K + +L E ++ +++ +M+ +R +
Sbjct: 221 RA--QVRDLEEKLETLRLKRAEDKAKLKE--LEKHKIQLEQVQEWKSKMQEQQADLQRRL 276
Query: 160 RKGYKPL-----SKQKSEEELKDKNQLLE--AVNKQLHQKLTET-QGELKDLTQKVELLE 211
++ K +K++ EE+ D +E ++K++ ++ E+ Q E++ L ++V+ L
Sbjct: 277 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 336
Query: 212 KFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQME 271
+ A +E KG D A S L +E D+++ + L K + +K ME
Sbjct: 337 TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLME 396
Query: 272 EL-QALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM 316
+ Q L+V + +E L Q +++ + A E+++EM
Sbjct: 397 KKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 442
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 45.4 bits (106), Expect = 6e-05
Identities = 41/135 (30%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 164 KPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAIL-- 221
K L + K+E E K K L+A ++LH K++E +L +K L+ DN +L
Sbjct: 1241 KVLQQVKAESEHKRKK--LDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE 1298
Query: 222 -ESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKL 280
E KG+ A + +L S+ + T + LL E +++L L + ++ EE +L+ +
Sbjct: 1299 AEKKGIKFAKDAASLESQLQDTQE-----LLQEETRQKLNL-SSRIRQLEEEKNSLQEQQ 1352
Query: 281 EMKEERVRFLEQQTL 295
E +EE + LE+Q L
Sbjct: 1353 EEEEEARKNLEKQVL 1367
Score = 39.7 bits (91), Expect = 0.004
Identities = 50/206 (24%), Positives = 92/206 (44%), Gaps = 24/206 (11%)
Query: 116 RSKEVDVSKQ-LHSGGPENDVTKIT---KLRRENGQMKATDTATRRNVRKGYKPLSKQKS 171
+ K++D Q LH+ E D ++ K + ++ T +KG K S
Sbjct: 1253 KRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAAS 1312
Query: 172 -EEELKDKNQLLEAVNKQ---LHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLD 227
E +L+D +LL+ +Q L ++ + + E L ++ E E+ R N LE + L
Sbjct: 1313 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN----LEKQVL- 1367
Query: 228 PALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERV 287
AL S+ LA ++ D + ++ LE +++L E +++EE KLE + R+
Sbjct: 1368 -ALQSQ-LADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 288 RFLEQQTLCNNQVNDLTTALKEMEQL 313
+ +++DLT L Q+
Sbjct: 1426 Q---------QELDDLTVDLDHQRQV 1442
Score = 36.2 bits (82), Expect = 0.039
Identities = 40/170 (23%), Positives = 83/170 (48%), Gaps = 25/170 (14%)
Query: 167 SKQKSEEELKDKNQLLEAVNKQLHQKL--TETQGELK-----DLTQKVELLEKFRDNCLA 219
S+ K+E++ +D ++ LEA+ +L L T Q EL+ ++ + + LE+ N A
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEA 1192
Query: 220 ILESKGLDPALGSETLASRQEST---------------TDHMDSMLLLETLQEELKLFNE 264
++ A E L+ + E TD+ + ++ LQ ++K +E
Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ-QVKAESE 1251
Query: 265 TAKKQME-ELQALKVKL-EMKEERVRFLEQQTLCNNQVNDLTTALKEMEQ 312
+K+++ ++Q L K+ E RV E+ + N++++++T L+E E+
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301
Score = 36.2 bits (82), Expect = 0.039
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 28/153 (18%)
Query: 167 SKQKSEEELKDKNQLLEAVNK---QLHQKLTETQGELKDLTQKVELLEKFRDNCLAILES 223
SK+K E +LKD +EA NK ++ ++L + Q ++KD +++E
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELE--------------- 1662
Query: 224 KGLDPALGSETLASRQESTTDHMDSMLLLETLQEE-LKLFNETAKKQMEELQALKVKLEM 282
E ASR E +S L++L+ E L+L E A + A + + E+
Sbjct: 1663 ---------EARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 1713
Query: 283 KEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+E ++ ++ L + ++E+ LE
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQLEEELE 1746
Score = 34.7 bits (78), Expect = 0.11
Identities = 54/253 (21%), Positives = 106/253 (41%), Gaps = 49/253 (19%)
Query: 102 DTQTRATSKSLLPVRSKEVDVSKQLHSGGPEND------------VTKITKLRRENGQMK 149
+ + +A + LL V+ K+ V +L ++ + T+L E +M+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 150 ATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQ-------LHQKLTETQG---- 198
A A ++ + + L + EEE ++NQ+L+ K+ L ++L E +G
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEE--ERNQILQNEKKKMQAHIQDLEEQLDEEEGARQK 968
Query: 199 ----------ELKDLTQKVELLEKFRDNCLAILESKGLDPALG--SETLASRQESTTD-- 244
++K + +++ LLE N I E K ++ + S LA +E +
Sbjct: 969 LQLEKVTAEAKIKKMEEEILLLED--QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 245 --HMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVND 302
+++ L+E LK +K +EL+ K KL+ E +Q Q+++
Sbjct: 1027 KIRNKQEVMISDLEERLK----KEEKTRQELEKAKRKLD--GETTDLQDQIAELQAQIDE 1080
Query: 303 LTTALKEMEQLLE 315
L L + E+ L+
Sbjct: 1081 LKLQLAKKEEELQ 1093
Score = 34.7 bits (78), Expect = 0.11
Identities = 44/174 (25%), Positives = 72/174 (41%), Gaps = 21/174 (12%)
Query: 152 DTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLE 211
D A K K LS ++ EE + + E NKQL + + D+ + V LE
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE 1531
Query: 212 KFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNE----TAK 267
K + LE + + E L ++T D+ L LE + +K E T
Sbjct: 1532 KSK----RALEQQVEEMRTQLEELEDELQATE---DAKLRLEVNMQAMKAQFERDLQTRD 1584
Query: 268 KQMEELQALKVK------LEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+Q EE + L +K E+++ER +Q+ L + LK++E +E
Sbjct: 1585 EQNEEKKRLLIKQVRELEAELEDER----KQRALAVASKKKMEIDLKDLEAQIE 1634
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 45.1 bits (105), Expect = 8e-05
Identities = 64/227 (28%), Positives = 100/227 (44%), Gaps = 39/227 (17%)
Query: 96 SGGQPAD-TQTRATSKSLLPVRSKEVDVSK----QLHSGGPENDVTKITKLRRENGQMKA 150
SG AD Q S++LL KEV +L + E+ V + T LRREN ++
Sbjct: 1461 SGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQET-LRRENKNLQE 1519
Query: 151 TDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQG-----ELKDLTQ 205
+ VR+G K L+ E++ +L+E ++ L ET+G E K L
Sbjct: 1520 EISNLTNQVREGTKNLT------EMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF 1573
Query: 206 KVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNET 265
++ELLE A LE K + E +Q+ T D + S L ++
Sbjct: 1574 QLELLE-----AKAELERKLSEKDEEIENFRRKQQCTIDSLQSSL-------------DS 1615
Query: 266 AKKQMEELQALKVKLEMKEERVRFLEQQTLC-NNQVNDLTTALKEME 311
K E+ LK K+ EE + +E Q C N QV++ T +L +++
Sbjct: 1616 EAKSRIEVTRLKKKM---EEDLNEMELQLSCANRQVSEATKSLGQLQ 1659
Score = 33.1 bits (74), Expect = 0.33
Identities = 50/228 (21%), Positives = 94/228 (41%), Gaps = 16/228 (7%)
Query: 95 LSGGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTA 154
L G +T++++ L ++ D+ ++ + E L + N +M
Sbjct: 1327 LRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMK 1386
Query: 155 TRRNVRKGYKPLSKQKSE-----EELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVEL 209
NV + + L K E +E + + A N L + + Q EL D
Sbjct: 1387 YENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSD--- 1443
Query: 210 LEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELK-LFNETAKK 268
L K R + A L+ K L + LA ++ H +S LL+ Q+E++ L E K
Sbjct: 1444 LGKVR-SAAARLDQKQLQ---SGKALADWKQK---HEESQALLDASQKEVQALSTELLKL 1496
Query: 269 QMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM 316
+ +++ + ++ E E+ + NQV + T L EME++ ++
Sbjct: 1497 KNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL 1544
Score = 32.3 bits (72), Expect = 0.57
Identities = 47/198 (23%), Positives = 89/198 (44%), Gaps = 37/198 (18%)
Query: 140 KLRRENGQMKATDTATRRNVRKGYKPLSKQ--KSEEELKDKNQLLE---AVNKQLHQKLT 194
+L + G +K + + N+ + L+++ K E EL N +E + QL + +
Sbjct: 1063 ELHKLEGNLKL-NRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVK 1121
Query: 195 ETQGELKDLTQKVEL-------LEKFRDNCLAILE--SKGLDPALGSE----TLASRQES 241
E Q ++KDL +K+E +E+ R + L ++ L+ GS + +QE+
Sbjct: 1122 ELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQET 1181
Query: 242 T-----TDHMDSMLLLETLQEELKLFNETA----KKQMEELQALKVKLEMKEERVRFLEQ 292
D ++ L ET LK + + + Q+E LQ +K KLE + ++
Sbjct: 1182 KFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQL--- 1238
Query: 293 QTLCNNQVNDLTTALKEM 310
+V+DL T +++M
Sbjct: 1239 ------EVDDLLTRVEQM 1250
Score = 28.5 bits (62), Expect = 8.2
Identities = 39/171 (22%), Positives = 62/171 (36%), Gaps = 30/171 (17%)
Query: 169 QKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNC----------L 218
QK EE+ + Q E K+ + ELK + LE+ R+N L
Sbjct: 1750 QKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRL 1809
Query: 219 AILESKGLDPALGSETLASRQESTTDHMDSML---------------LLETLQEELKLFN 263
A E L +GS + ES ++ L LE +EL
Sbjct: 1810 AEAEQMAL---MGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQA 1866
Query: 264 ETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLL 314
E KK + +Q KL++K + + +Q + Q N + K+ + L
Sbjct: 1867 EEDKKNLSRMQTQMDKLQLKVQ--NYKQQVEVAETQANQYLSKYKKQQHEL 1915
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 45.1 bits (105), Expect = 8e-05
Identities = 40/187 (21%), Positives = 85/187 (45%), Gaps = 20/187 (10%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTET 196
+I +L E G++KA + ++ + Q +E+L E + K L K+ +
Sbjct: 1367 RIQQLTEEIGRLKAEIARSNASLTNNQNLI--QSLKEDLNKVRTEKETIQKDLDAKIIDI 1424
Query: 197 QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQ 256
Q ++K +TQ ++ +++ + A + + + +S+ DH + + ++ +Q
Sbjct: 1425 QEKVKTITQVKKIGRRYKTQYEEL-------KAQQDKVMETSAQSSGDHQEQHVSVQEMQ 1477
Query: 257 EELKLFN--ETAKKQME-ELQALKVKLEMKEERVRFLEQQTL--------CNNQVNDLTT 305
E + N ET K +E +++ L+ L KE R L++QT+ + D TT
Sbjct: 1478 ELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTT 1537
Query: 306 ALKEMEQ 312
+++ Q
Sbjct: 1538 QEEQLRQ 1544
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/168 (26%), Positives = 84/168 (50%), Gaps = 24/168 (14%)
Query: 163 YKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAI-- 220
Y + K+ S + + N+ E + L +L + +LK LT+K + LE +D +AI
Sbjct: 54 YFEIEKRLSHSQERLVNETREC--QSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQS 111
Query: 221 --------LESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNET---AKKQ 269
LE++ D +E L+ E T+ ++ L E+LK N T + +
Sbjct: 112 QFTRTKEELEAEKRDLIRTNERLSQELEYLTED------VKRLNEKLKESNTTKGELQLK 165
Query: 270 MEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALK-EMEQLLEM 316
++ELQA V ++ +E+R+ +++ L ++Q L T LK + ++LL +
Sbjct: 166 LDELQASDVSVKYREKRLE--QEKELLHSQNTWLNTELKTKTDELLAL 211
Score = 37.7 bits (86), Expect = 0.013
Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 9/152 (5%)
Query: 170 KSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNC-LAILESKGLDP 228
+++EEL+ + + L N++L Q+L ++K L +K++ + L + E + D
Sbjct: 115 RTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDV 174
Query: 229 ALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVR 288
++ QE H + L L+ + +++ E+ LK LE K+E V
Sbjct: 175 SVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVS 234
Query: 289 FLEQQ--------TLCNNQVNDLTTALKEMEQ 312
LE+Q V DL T LKE ++
Sbjct: 235 RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKE 266
Score = 33.9 bits (76), Expect = 0.19
Identities = 46/184 (25%), Positives = 86/184 (46%), Gaps = 22/184 (11%)
Query: 141 LRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGEL 200
++R N ++K ++T T+ ++ L Q S+ +K + + LE + LH + T EL
Sbjct: 145 VKRLNEKLKESNT-TKGELQLKLDEL--QASDVSVKYREKRLEQEKELLHSQNTWLNTEL 201
Query: 201 KDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELK 260
K T+ ELL R+ ILE K L +++E + + M L+T E L+
Sbjct: 202 K--TKTDELLALGREKGNEILELKC--------NLENKKEEVSRLEEQMNGLKTSNEHLQ 251
Query: 261 LFNETAKKQMEELQALKVKLEMK--EERVRFLEQQTLCNN-------QVNDLTTALKEME 311
E +++E + + +E K E ++ L + + N+LT A++E+
Sbjct: 252 KHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH 311
Query: 312 QLLE 315
+LL+
Sbjct: 312 KLLK 315
Score = 30.0 bits (66), Expect = 2.8
Identities = 43/218 (19%), Positives = 90/218 (41%), Gaps = 20/218 (9%)
Query: 101 ADTQTRATSKSLLPVRSKEVDVSKQLHS--GGPENDVTKITKLRRENGQMKATDTATRRN 158
A+ + K ++ EV +S+Q S +T L+ G ++ ++T T++
Sbjct: 777 AEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQR 836
Query: 159 VRKGYKPLS------KQKSEEELKDKNQLLEAVNKQL----HQKLTETQGEL------KD 202
+ + L K+K E E++ ++ L ++ QL Q TET L K+
Sbjct: 837 LSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKN 896
Query: 203 LTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLF 262
+++ L++ N + S+ + S +E D + + E +LK
Sbjct: 897 AQKEIATLKQHLSNMEVQVASQSSQRT--GKGQPSNKEDVDDLVSQLRQTEEQVNDLKER 954
Query: 263 NETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQV 300
+T+ +E+ QA+ LE + + + ++ N +V
Sbjct: 955 LKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 44.7 bits (104), Expect = 1e-04
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 30/204 (14%)
Query: 129 GGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELK-------DKNQL 181
G PE + ++ +L E + + + + RK KQ+ EEL+ ++N
Sbjct: 269 GEPEKE-QRVQQLESELSKKRKKCESLEQEARK------KQRRCEELELQLRQAQNENAR 321
Query: 182 LEAVNKQLHQKLTET-QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGS-------- 232
L N +L + TE Q E ++ + +LL ++ A+ +S+GL L S
Sbjct: 322 LVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHM 381
Query: 233 -ETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEE----LQALKVKLEMKEERV 287
E RQ+ +H + L L QEE++ + + E +Q L+ L+ + RV
Sbjct: 382 REVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQARV 441
Query: 288 RFLEQQTLCNNQVNDLTTALKEME 311
R LE+Q C +Q + +E++
Sbjct: 442 RELEEQ--CRSQTEQFSLLAQELQ 463
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 44.7 bits (104), Expect = 1e-04
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 30/204 (14%)
Query: 129 GGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELK-------DKNQL 181
G PE + ++ +L E + + + + RK KQ+ EEL+ ++N
Sbjct: 329 GEPEKE-QRVQQLESELSKKRKKCESLEQEARK------KQRRCEELELQLRQAQNENAR 381
Query: 182 LEAVNKQLHQKLTET-QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGS-------- 232
L N +L + TE Q E ++ + +LL ++ A+ +S+GL L S
Sbjct: 382 LVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHM 441
Query: 233 -ETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEE----LQALKVKLEMKEERV 287
E RQ+ +H + L L QEE++ + + E +Q L+ L+ + RV
Sbjct: 442 REVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQARV 501
Query: 288 RFLEQQTLCNNQVNDLTTALKEME 311
R LE+Q C +Q + +E++
Sbjct: 502 RELEEQ--CRSQTEQFSLLAQELQ 523
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
sapiens]
Length = 436
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 22/159 (13%)
Query: 118 KEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKD 177
K+ + KQ++ END KL+ E + +A + A +N + Y E+EL+
Sbjct: 257 KQESLEKQINDLKSENDALN-EKLKSEEQKRRAREKANLKNPQIMYL-------EQELES 308
Query: 178 KNQLLEAVNKQLHQ---KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSET 234
+LE N++LHQ KL + + + + T V+ L++F+ E++ L +
Sbjct: 309 LKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ------ENEELKARMDKHM 362
Query: 235 LASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEEL 273
SRQ ST + +L E+L++E K+ N+ + EEL
Sbjct: 363 AISRQLST----EQAVLQESLEKESKV-NKRLSMENEEL 396
Score = 33.9 bits (76), Expect = 0.19
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 18/231 (7%)
Query: 95 LSGGQPADTQTRATSKSLLPVRSKEVDVS---KQLHSGGPENDVTKITKLRRENGQMKAT 151
LS + A Q + S+ L+ +R + V S ++L E +++ +
Sbjct: 110 LSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTER 169
Query: 152 DTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLE 211
+ + + Y+ L EE K K QL E + T ++K+ELL+
Sbjct: 170 ENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLK 229
Query: 212 KFRDNCLAIL------ESKGLDPALGSET---------LASRQESTTDHMDSMLLLETLQ 256
K + L+ + E K L+ L + L S ++ + + S +
Sbjct: 230 KAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAR 289
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTAL 307
E+ L N +EL++LK LE+K E++ + + + ++ D TAL
Sbjct: 290 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 340
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 22/159 (13%)
Query: 118 KEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKD 177
K+ + KQ++ END KL+ E + +A + A +N + Y E+EL+
Sbjct: 1091 KQESLEKQINDLKSENDALN-EKLKSEEQKRRAREKANLKNPQIMYL-------EQELES 1142
Query: 178 KNQLLEAVNKQLHQ---KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSET 234
+LE N++LHQ KL + + + + T V+ L++F+ E++ L +
Sbjct: 1143 LKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ------ENEELKARMDKHM 1196
Query: 235 LASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEEL 273
SRQ ST + +L E+L++E K+ N+ + EEL
Sbjct: 1197 AISRQLST----EQAVLQESLEKESKV-NKRLSMENEEL 1230
Score = 33.9 bits (76), Expect = 0.19
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 18/231 (7%)
Query: 95 LSGGQPADTQTRATSKSLLPVRSKEVDVS---KQLHSGGPENDVTKITKLRRENGQMKAT 151
LS + A Q + S+ L+ +R + V S ++L E +++ +
Sbjct: 944 LSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTER 1003
Query: 152 DTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLE 211
+ + + Y+ L EE K K QL E + T ++K+ELL+
Sbjct: 1004 ENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLK 1063
Query: 212 KFRDNCLAIL------ESKGLDPALGSET---------LASRQESTTDHMDSMLLLETLQ 256
K + L+ + E K L+ L + L S ++ + + S +
Sbjct: 1064 KAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAR 1123
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTAL 307
E+ L N +EL++LK LE+K E++ + + + ++ D TAL
Sbjct: 1124 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 1174
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 22/159 (13%)
Query: 118 KEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKD 177
K+ + KQ++ END KL+ E + +A + A +N + Y E+EL+
Sbjct: 1037 KQESLEKQINDLKSENDALN-EKLKSEEQKRRAREKANLKNPQIMYL-------EQELES 1088
Query: 178 KNQLLEAVNKQLHQ---KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSET 234
+LE N++LHQ KL + + + + T V+ L++F+ E++ L +
Sbjct: 1089 LKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ------ENEELKARMDKHM 1142
Query: 235 LASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEEL 273
SRQ ST + +L E+L++E K+ N+ + EEL
Sbjct: 1143 AISRQLST----EQAVLQESLEKESKV-NKRLSMENEEL 1176
Score = 33.9 bits (76), Expect = 0.19
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 18/231 (7%)
Query: 95 LSGGQPADTQTRATSKSLLPVRSKEVDVS---KQLHSGGPENDVTKITKLRRENGQMKAT 151
LS + A Q + S+ L+ +R + V S ++L E +++ +
Sbjct: 890 LSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTER 949
Query: 152 DTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLE 211
+ + + Y+ L EE K K QL E + T ++K+ELL+
Sbjct: 950 ENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLK 1009
Query: 212 KFRDNCLAIL------ESKGLDPALGSET---------LASRQESTTDHMDSMLLLETLQ 256
K + L+ + E K L+ L + L S ++ + + S +
Sbjct: 1010 KAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAR 1069
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTAL 307
E+ L N +EL++LK LE+K E++ + + + ++ D TAL
Sbjct: 1070 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 1120
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
sapiens]
Length = 517
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 22/159 (13%)
Query: 118 KEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKD 177
K+ + KQ++ END KL+ E + +A + A +N + Y E+EL+
Sbjct: 338 KQESLEKQINDLKSENDALN-EKLKSEEQKRRAREKANLKNPQIMYL-------EQELES 389
Query: 178 KNQLLEAVNKQLHQ---KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSET 234
+LE N++LHQ KL + + + + T V+ L++F+ E++ L +
Sbjct: 390 LKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ------ENEELKARMDKHM 443
Query: 235 LASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEEL 273
SRQ ST + +L E+L++E K+ N+ + EEL
Sbjct: 444 AISRQLST----EQAVLQESLEKESKV-NKRLSMENEEL 477
Score = 33.9 bits (76), Expect = 0.19
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 18/231 (7%)
Query: 95 LSGGQPADTQTRATSKSLLPVRSKEVDVS---KQLHSGGPENDVTKITKLRRENGQMKAT 151
LS + A Q + S+ L+ +R + V S ++L E +++ +
Sbjct: 191 LSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTER 250
Query: 152 DTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLE 211
+ + + Y+ L EE K K QL E + T ++K+ELL+
Sbjct: 251 ENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLK 310
Query: 212 KFRDNCLAIL------ESKGLDPALGSET---------LASRQESTTDHMDSMLLLETLQ 256
K + L+ + E K L+ L + L S ++ + + S +
Sbjct: 311 KAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAR 370
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTAL 307
E+ L N +EL++LK LE+K E++ + + + ++ D TAL
Sbjct: 371 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTAL 421
>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
[Homo sapiens]
Length = 1025
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 22/190 (11%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEEL-KDKNQLLEAVNKQLHQKLTE 195
++ KLR E ++ A +TA + + K +++ E EL K + + +VN + +
Sbjct: 749 ELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQ 808
Query: 196 TQGELKDLTQKVELL-EKFRDNCLAILESKGLDPALGSETLASRQ--------ESTTDHM 246
EL+ + +++E+L E++ C LE+ L AL +E A RQ + +
Sbjct: 809 YLEELQSVQRELEVLSEQYSQKC---LENAHLAQALEAERQALRQCQRENQELNAHNQEL 865
Query: 247 DSMLLLETLQEELKLFNE-------TAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQ 299
++ L E + L + + Q ++ L+V L +KE +++L+Q+ ++
Sbjct: 866 NNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQE--ISSL 923
Query: 300 VNDLTTALKE 309
++L TAL++
Sbjct: 924 KDELQTALRD 933
>gi|50980307 myosin phosphatase-Rho interacting protein isoform 1
[Homo sapiens]
Length = 1038
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 22/190 (11%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEEL-KDKNQLLEAVNKQLHQKLTE 195
++ KLR E ++ A +TA + + K +++ E EL K + + +VN + +
Sbjct: 749 ELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQ 808
Query: 196 TQGELKDLTQKVELL-EKFRDNCLAILESKGLDPALGSETLASRQ--------ESTTDHM 246
EL+ + +++E+L E++ C LE+ L AL +E A RQ + +
Sbjct: 809 YLEELQSVQRELEVLSEQYSQKC---LENAHLAQALEAERQALRQCQRENQELNAHNQEL 865
Query: 247 DSMLLLETLQEELKLFNE-------TAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQ 299
++ L E + L + + Q ++ L+V L +KE +++L+Q+ ++
Sbjct: 866 NNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQE--ISSL 923
Query: 300 VNDLTTALKE 309
++L TAL++
Sbjct: 924 KDELQTALRD 933
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 43.1 bits (100), Expect = 3e-04
Identities = 40/156 (25%), Positives = 80/156 (51%), Gaps = 22/156 (14%)
Query: 166 LSKQKSEEELKDKNQLLEAVN---KQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILE 222
LSK++ + +++++N+ +E + ++L Q L + D QKVE + F +E
Sbjct: 2130 LSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA----DTFQKVEDRKHF-----GAVE 2180
Query: 223 SKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEM 282
+K P L E + D + + L+E+L+ F E + + EE+Q L ++LE+
Sbjct: 2181 AK---PELSLEVQLQAERDAIDRKEKEIT--NLEEQLEQFREELENKNEEVQQLHMQLEI 2235
Query: 283 KEE----RVRFLEQQT-LCNNQVNDLTTALKEMEQL 313
+++ R++ LEQ+ L + + L A+KE + +
Sbjct: 2236 QKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM 2271
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 21/123 (17%)
Query: 171 SEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPAL 230
SE+ LK+ + LE + ++ + L ET+ D Q + +EK D +
Sbjct: 3341 SEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEK--------------DRQV 3386
Query: 231 GSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFL 290
+TL + QE+ T+ M L++ E+L ++Q+EE + KL+++ +R++ +
Sbjct: 3387 HRKTLQTEQEANTEGQKKMHELQSKVEDL-------QRQLEEKRQQVYKLDLEGQRLQGI 3439
Query: 291 EQQ 293
Q+
Sbjct: 3440 MQE 3442
Score = 33.1 bits (74), Expect = 0.33
Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 10/152 (6%)
Query: 173 EELKDK-----NQLLEAVNKQLHQKLTETQGELKDLTQKVELL----EKFRDNCLAILES 223
E+LKD Q ++ + ++ QK+ Q E +L K L K +D +++ S
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNS 712
Query: 224 KGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQ-ALKVKLEM 282
K + L L E LE +EL+L E +KQM+E + L+ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 283 KEERVRFLEQQTLCNNQVNDLTTALKEMEQLL 314
E L+ + + + T + + E+L+
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Score = 31.6 bits (70), Expect = 0.96
Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 13/128 (10%)
Query: 164 KPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILES 223
K + ++K ELKDK + + +L +++ + E+K++ K+EL + + E
Sbjct: 337 KIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNM--KLELTNSKQKERQSSEEI 394
Query: 224 KGLDPALGSETLASRQESTTDHMDSML---LLETLQEELKLFNETAKKQMEELQALKVKL 280
K L + E L R +H DS +++ +++E + E + +++E+ ++ +
Sbjct: 395 KQLMGTV--EELQKR-----NHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI-V 446
Query: 281 EMKEERVR 288
+MK+E +R
Sbjct: 447 QMKQELIR 454
Score = 31.6 bits (70), Expect = 0.96
Identities = 46/233 (19%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 100 PADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTK--ITKLRRENGQMKATDTATRR 157
P + R + +SK+ K++ EN+ K +L E + + T + +
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855
Query: 158 NVRKGYKPLSKQ--------------KSEEELKDKNQLLEAVNKQLH-QKLTETQGELKD 202
N Y+ L ++ K+++EL+ K++L +A+N++LH Q++ T ++K
Sbjct: 856 NFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKL-KALNEELHLQRINPTTVKMKS 914
Query: 203 LTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLF 262
+ ++ + LE + +E + + + + ++ L L E+LK
Sbjct: 915 -----SVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQK 969
Query: 263 NETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+ EE+++LK + E R R LE + +N+ ++ + ++ LL+
Sbjct: 970 HGEISFLNEEVKSLKQEKEQVSLRCRELE-IIINHNRAENVQSCDTQVSSLLD 1021
Score = 30.0 bits (66), Expect = 2.8
Identities = 32/179 (17%), Positives = 74/179 (41%), Gaps = 13/179 (7%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTET 196
++ L+RE ++ + +V LSK K E E+ L+++ Q + K E
Sbjct: 2429 ELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEE 2488
Query: 197 QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQ 256
G+ + + LL+ + + +K L+ + + QE E LQ
Sbjct: 2489 NGKGSIINLETRLLQ-----LESTVSAKDLELTQCYKQIKDMQE------QGQFETEMLQ 2537
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+++ + ++++ +++LE +E +F + +++ T ++ + QL E
Sbjct: 2538 KKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPE--RTNIQNLNQLRE 2594
>gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo
sapiens]
Length = 395
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 10/151 (6%)
Query: 148 MKATDTATRRNVRKGYKPLSKQ-KSEEE---LKDKNQLLEAVNKQLHQKLTETQGELKDL 203
+K A ++ Y+ + +Q KSE+E LKD + +A +++L QKL + EL+ L
Sbjct: 222 LKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERF-QARSQELEQKLLCKEQELEQL 280
Query: 204 TQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFN 263
TQK + LE C A+ K A ++ + QE + + L+ Q++L+
Sbjct: 281 TQKQKRLE---GQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQ 337
Query: 264 ETAKK--QMEELQALKVKLEMKEERVRFLEQ 292
+ A K Q +E++ +V ++ E+ L+Q
Sbjct: 338 QEACKLHQEKEMEVYRVTESLQREKAGLLKQ 368
>gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo
sapiens]
Length = 462
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 10/151 (6%)
Query: 148 MKATDTATRRNVRKGYKPLSKQ-KSEEE---LKDKNQLLEAVNKQLHQKLTETQGELKDL 203
+K A ++ Y+ + +Q KSE+E LKD + +A +++L QKL + EL+ L
Sbjct: 222 LKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERF-QARSQELEQKLLCKEQELEQL 280
Query: 204 TQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFN 263
TQK + LE C A+ K A ++ + QE + + L+ Q++L+
Sbjct: 281 TQKQKRLE---GQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQ 337
Query: 264 ETAKK--QMEELQALKVKLEMKEERVRFLEQ 292
+ A K Q +E++ +V ++ E+ L+Q
Sbjct: 338 QEACKLHQEKEMEVYRVTESLQREKAGLLKQ 368
>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
sapiens]
Length = 731
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 10/151 (6%)
Query: 148 MKATDTATRRNVRKGYKPLSKQ-KSEEE---LKDKNQLLEAVNKQLHQKLTETQGELKDL 203
+K A ++ Y+ + +Q KSE+E LKD + +A +++L QKL + EL+ L
Sbjct: 222 LKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERF-QARSQELEQKLLCKEQELEQL 280
Query: 204 TQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFN 263
TQK + LE C A+ K A ++ + QE + + L+ Q++L+
Sbjct: 281 TQKQKRLE---GQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQ 337
Query: 264 ETAKK--QMEELQALKVKLEMKEERVRFLEQ 292
+ A K Q +E++ +V ++ E+ L+Q
Sbjct: 338 QEACKLHQEKEMEVYRVTESLQREKAGLLKQ 368
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 42.7 bits (99), Expect = 4e-04
Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 15/153 (9%)
Query: 168 KQKSEEEL---KDKNQLLEAVNKQLHQKLTETQGELKDLT-QKVELLEKFRDNCLAILES 223
K+K E+L KD ++L A K + KL + D T ++ ++LE+ R I E
Sbjct: 446 KEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQE---IAEQ 502
Query: 224 KGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKL-EM 282
K + + + + SR E T + ++ +LQ+E+ + + KK +LQA+K ++ ++
Sbjct: 503 KRREREI-QQQMESRDEETLELKETY---SSLQQEVDIKTKKLKKLFSKLQAVKAEIHDL 558
Query: 283 KEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+EE ++ E+Q L Q N+LT LK ++E
Sbjct: 559 QEEHIK--ERQELEQTQ-NELTRELKLKHLIIE 588
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 42.7 bits (99), Expect = 4e-04
Identities = 50/219 (22%), Positives = 101/219 (46%), Gaps = 20/219 (9%)
Query: 112 LLPVRSKEVDVSKQLHSGGPENDVTKITKLR-RENGQMKATDTATRRNVRKGYKPLSKQK 170
L+ +R + + KQL D I + R+ Q + + V ++P+S+ +
Sbjct: 2048 LMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQ 2107
Query: 171 SEEELKDKNQLLEAVNK--QLHQKLTETQGELKDLTQKVELLEKFR----DNCLAILESK 224
+ E + N L E +K +L + Q ++++ +++E LE FR + L + + K
Sbjct: 2108 TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLE-FRVRELEQALLVEDRK 2166
Query: 225 GLD-----PALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVK 279
P L E + D + + L+E+L+ F E + + EE+Q L ++
Sbjct: 2167 HFGAVEAKPELSLEVQLQAERDAIDRKEKEIT--NLEEQLEQFREELENKNEEVQQLHMQ 2224
Query: 280 LEMKEE----RVRFLEQQT-LCNNQVNDLTTALKEMEQL 313
LE++++ R++ LEQ+ L + + L A+KE + +
Sbjct: 2225 LEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM 2263
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 21/123 (17%)
Query: 171 SEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPAL 230
SE+ LK+ + LE + ++ + L ET+ D Q + +EK D +
Sbjct: 3333 SEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEK--------------DRQV 3378
Query: 231 GSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFL 290
+TL + QE+ T+ M L++ E+L ++Q+EE + KL+++ +R++ +
Sbjct: 3379 HRKTLQTEQEANTEGQKKMHELQSKVEDL-------QRQLEEKRQQVYKLDLEGQRLQGI 3431
Query: 291 EQQ 293
Q+
Sbjct: 3432 MQE 3434
Score = 33.1 bits (74), Expect = 0.33
Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 10/152 (6%)
Query: 173 EELKDK-----NQLLEAVNKQLHQKLTETQGELKDLTQKVELL----EKFRDNCLAILES 223
E+LKD Q ++ + ++ QK+ Q E +L K L K +D +++ S
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNS 712
Query: 224 KGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQ-ALKVKLEM 282
K + L L E LE +EL+L E +KQM+E + L+ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 283 KEERVRFLEQQTLCNNQVNDLTTALKEMEQLL 314
E L+ + + + T + + E+L+
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Score = 31.6 bits (70), Expect = 0.96
Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 13/128 (10%)
Query: 164 KPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILES 223
K + ++K ELKDK + + +L +++ + E+K++ K+EL + + E
Sbjct: 337 KIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNM--KLELTNSKQKERQSSEEI 394
Query: 224 KGLDPALGSETLASRQESTTDHMDSML---LLETLQEELKLFNETAKKQMEELQALKVKL 280
K L + E L R +H DS +++ +++E + E + +++E+ ++ +
Sbjct: 395 KQLMGTV--EELQKR-----NHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI-V 446
Query: 281 EMKEERVR 288
+MK+E +R
Sbjct: 447 QMKQELIR 454
Score = 31.6 bits (70), Expect = 0.96
Identities = 46/233 (19%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 100 PADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTK--ITKLRRENGQMKATDTATRR 157
P + R + +SK+ K++ EN+ K +L E + + T + +
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855
Query: 158 NVRKGYKPLSKQ--------------KSEEELKDKNQLLEAVNKQLH-QKLTETQGELKD 202
N Y+ L ++ K+++EL+ K++L +A+N++LH Q++ T ++K
Sbjct: 856 NFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKL-KALNEELHLQRINPTTVKMKS 914
Query: 203 LTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLF 262
+ ++ + LE + +E + + + + ++ L L E+LK
Sbjct: 915 -----SVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQK 969
Query: 263 NETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+ EE+++LK + E R R LE + +N+ ++ + ++ LL+
Sbjct: 970 HGEISFLNEEVKSLKQEKEQVSLRCRELE-IIINHNRAENVQSCDTQVSSLLD 1021
Score = 30.0 bits (66), Expect = 2.8
Identities = 32/179 (17%), Positives = 74/179 (41%), Gaps = 13/179 (7%)
Query: 137 KITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTET 196
++ L+RE ++ + +V LSK K E E+ L+++ Q + K E
Sbjct: 2421 ELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEE 2480
Query: 197 QGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQ 256
G+ + + LL+ + + +K L+ + + QE E LQ
Sbjct: 2481 NGKGSIINLETRLLQ-----LESTVSAKDLELTQCYKQIKDMQE------QGQFETEMLQ 2529
Query: 257 EELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLE 315
+++ + ++++ +++LE +E +F + +++ T ++ + QL E
Sbjct: 2530 KKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPE--RTNIQNLNQLRE 2586
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 42.7 bits (99), Expect = 4e-04
Identities = 54/195 (27%), Positives = 88/195 (45%), Gaps = 19/195 (9%)
Query: 132 ENDVTKITKLRRENGQMKA----TDTATRRN--VRKGYKPLSKQKSEEELKDKNQLLEAV 185
E D KL NG + T+T + N V+K + L KQ SE LK KNQ L+
Sbjct: 1541 EEDSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISE--LKIKNQQLDLE 1598
Query: 186 NKQLHQKLTETQGELKDLTQKVE--LLEKFRDNCLAILESKGLDPALGSETLASRQESTT 243
N +L QK ++ Q +L++L Q++ L +K ++ + LE + E ++E
Sbjct: 1599 NTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEER------EQEKFNLKEELER 1652
Query: 244 DHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVR---FLEQQTLCNNQV 300
+ S L+ +L+ EL +E LK +LE ++ R + Q ++ +
Sbjct: 1653 CKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVL 1712
Query: 301 NDLTTALKEMEQLLE 315
+ LKE E L E
Sbjct: 1713 SYNEKLLKEKEALSE 1727
Score = 33.1 bits (74), Expect = 0.33
Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 34/198 (17%)
Query: 132 ENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQ 191
E + TK+ +L R+ + + T +++V LS + EEELK L+ ++ Q
Sbjct: 1461 ELEKTKLQELTRKLKE-RVTILVKQKDV------LSHGEKEEELKAMMHDLQITCSEMQQ 1513
Query: 192 KLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLL 251
K+ + E + L Q+ +L N + L + L TL QE +
Sbjct: 1514 KVELLRYESEKLQQENSILR----NEITTLNEEDSISNLKLGTLNGSQE------EMWQK 1563
Query: 252 LETLQEE---LKLFNETAKKQMEELQALKVKLEMK-----------EERVRFLEQ---QT 294
ET+++E ++ E KKQ+ EL+ +L+++ +E+++ L Q +
Sbjct: 1564 TETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEM 1623
Query: 295 LCNNQVNDLTTALKEMEQ 312
LC + +AL+E EQ
Sbjct: 1624 LCQKEKEPGNSALEEREQ 1641
Score = 32.7 bits (73), Expect = 0.43
Identities = 56/210 (26%), Positives = 85/210 (40%), Gaps = 38/210 (18%)
Query: 110 KSLLPVRSKEVDVSKQLHSGGPENDVTKITK-LRRENGQMKATDTATRRN-VRKGYKPLS 167
KS L V +E + KQ +V + K L+ G+ A + AT + + K LS
Sbjct: 1792 KSDLRVTQQEKEALKQ--------EVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLS 1843
Query: 168 KQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLD 227
K + + ++ QLL N++L + T+ EL +KV LE + L K L+
Sbjct: 1844 WDKLDHLMNEEQQLLWQENERLQTMVQNTKAELTHSREKVRQLE----SNLLPKHQKHLN 1899
Query: 228 PALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEM----K 283
P S + T QE+L L E + Q E+ A + +M +
Sbjct: 1900 P-------------------SGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQ 1940
Query: 284 EERVRFLEQQTLCNNQVNDLTTALKEMEQL 313
E LE + L QV L L EM+ L
Sbjct: 1941 ELETIHLENEGLKKKQVK-LDEQLMEMQHL 1969
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,546,494
Number of Sequences: 37866
Number of extensions: 499913
Number of successful extensions: 4095
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 490
Number of HSP's that attempted gapping in prelim test: 2848
Number of HSP's gapped (non-prelim): 1526
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.