Guide to the Human Genome
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Search of human proteins with 218081589

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|218081589 anoctamin 5 isoform b [Homo sapiens]
         (912 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|218081589 anoctamin 5 isoform b [Homo sapiens]                    1862   0.0  
gi|47106048 anoctamin 5 isoform a [Homo sapiens]                     1857   0.0  
gi|218156303 anoctamin 6 isoform b [Homo sapiens]                     880   0.0  
gi|218156299 anoctamin 6 isoform a [Homo sapiens]                     880   0.0  
gi|218156307 anoctamin 6 isoform c [Homo sapiens]                     837   0.0  
gi|218156305 anoctamin 6 isoform c [Homo sapiens]                     837   0.0  
gi|218084958 anoctamin 4 [Homo sapiens]                               725   0.0  
gi|156766084 transmembrane protein 16C [Homo sapiens]                 692   0.0  
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho...   631   0.0  
gi|209862785 anoctamin 2 [Homo sapiens]                               623   e-178
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s...   543   e-154
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]     437   e-122
gi|94536803 transmembrane protein 16K [Homo sapiens]                  153   8e-37
gi|55741655 anoctamin 8 [Homo sapiens]                                110   5e-24
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]            67   8e-11
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]            66   1e-10
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]            66   1e-10
gi|22748943 hypothetical protein LOC145483 [Homo sapiens]              37   0.084
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]              33   0.93 
gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens]      32   2.7  
gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens]      32   2.7  
gi|5454014 tripartite motif-containing 38 [Homo sapiens]               31   4.6  
gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens]     31   4.6  
gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens]     31   4.6  
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]            31   6.0  
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s...    31   6.0  
gi|44955929 calmodulin regulated spectrin-associated protein 1-l...    31   6.0  
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H...    30   7.8  
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H...    30   7.8  
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H...    30   7.8  

>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
          Length = 912

 Score = 1862 bits (4823), Expect = 0.0
 Identities = 912/912 (100%), Positives = 912/912 (100%)

Query: 1   MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF 60
           MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF
Sbjct: 1   MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF 60

Query: 61  QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR 120
           QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR
Sbjct: 61  QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR 120

Query: 121 DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY 180
           DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY
Sbjct: 121 DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY 180

Query: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240
           PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL
Sbjct: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240

Query: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300
           NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG
Sbjct: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300

Query: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360
           IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD
Sbjct: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360

Query: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420
           YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ
Sbjct: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420

Query: 421 QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI 480
           QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI
Sbjct: 421 QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI 480

Query: 481 VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT 540
           VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT
Sbjct: 481 VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT 540

Query: 541 KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC 600
           KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC
Sbjct: 541 KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC 600

Query: 601 DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL 660
           DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL
Sbjct: 601 DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL 660

Query: 661 ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA 720
           ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA
Sbjct: 661 ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA 720

Query: 721 SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL 780
           SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL
Sbjct: 721 SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL 780

Query: 781 SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH 840
           SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH
Sbjct: 781 SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH 840

Query: 841 VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI 900
           VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI
Sbjct: 841 VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI 900

Query: 901 EENKAQLAKSTL 912
           EENKAQLAKSTL
Sbjct: 901 EENKAQLAKSTL 912


>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
          Length = 913

 Score = 1857 bits (4811), Expect = 0.0
 Identities = 912/913 (99%), Positives = 912/913 (99%), Gaps = 1/913 (0%)

Query: 1   MGDPDLLEVLAEEGEKVNKHIDYSFQMSE-SLSSRETSFLINEETMPAKRFNLFLRRRLM 59
           MGDPDLLEVLAEEGEKVNKHIDYSFQMSE SLSSRETSFLINEETMPAKRFNLFLRRRLM
Sbjct: 1   MGDPDLLEVLAEEGEKVNKHIDYSFQMSEQSLSSRETSFLINEETMPAKRFNLFLRRRLM 60

Query: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK 119
           FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK
Sbjct: 61  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK 120

Query: 120 RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK 179
           RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK
Sbjct: 121 RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK 180

Query: 180 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239
           YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL
Sbjct: 181 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 240

Query: 240 LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI 299
           LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI
Sbjct: 241 LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI 300

Query: 300 GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC 359
           GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC
Sbjct: 301 GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC 360

Query: 360 DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE 419
           DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE
Sbjct: 361 DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE 420

Query: 420 QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV 479
           QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV
Sbjct: 421 QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV 480

Query: 480 IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI 539
           IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI
Sbjct: 481 IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI 540

Query: 540 TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE 599
           TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE
Sbjct: 541 TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE 600

Query: 600 CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD 659
           CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD
Sbjct: 601 CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD 660

Query: 660 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 719
           LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV
Sbjct: 661 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 720

Query: 720 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 779
           ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS
Sbjct: 721 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 780

Query: 780 LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME 839
           LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME
Sbjct: 781 LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME 840

Query: 840 HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM 899
           HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM
Sbjct: 841 HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM 900

Query: 900 IEENKAQLAKSTL 912
           IEENKAQLAKSTL
Sbjct: 901 IEENKAQLAKSTL 913


>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
          Length = 892

 Score =  880 bits (2275), Expect = 0.0
 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%)

Query: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 32  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 91

Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 92  LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 149

Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 150 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 209

Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 210 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 269

Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 270 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 329

Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 330 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 389

Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 390 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 439

Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 440 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 499

Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 500 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 559

Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 560 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 619

Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 620 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 679

Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 680 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 739

Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 740 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 799

Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 874
             +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K    +I+REK +T K+
Sbjct: 800 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 859

Query: 875 LHDFELNKLKENLGI 889
           LH+  L  + +N+G+
Sbjct: 860 LHENHLKDMTKNMGV 874


>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
          Length = 910

 Score =  880 bits (2275), Expect = 0.0
 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%)

Query: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 50  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109

Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167

Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227

Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287

Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347

Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407

Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457

Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517

Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577

Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637

Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697

Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757

Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817

Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 874
             +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K    +I+REK +T K+
Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 877

Query: 875 LHDFELNKLKENLGI 889
           LH+  L  + +N+G+
Sbjct: 878 LHENHLKDMTKNMGV 892


>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score =  837 bits (2162), Expect = 0.0
 Identities = 417/819 (50%), Positives = 569/819 (69%), Gaps = 37/819 (4%)

Query: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 50  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109

Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167

Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227

Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287

Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347

Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407

Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457

Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517

Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577

Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637

Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697

Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757

Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817

Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMI 853
             +Y HN+ +WHV+AAK+ FIIVME++  L +   + MI
Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEYLALLPRLGHSGMI 856


>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score =  837 bits (2162), Expect = 0.0
 Identities = 417/819 (50%), Positives = 569/819 (69%), Gaps = 37/819 (4%)

Query: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 50  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109

Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167

Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227

Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287

Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347

Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407

Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457

Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517

Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577

Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637

Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697

Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757

Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817

Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMI 853
             +Y HN+ +WHV+AAK+ FIIVME++  L +   + MI
Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEYLALLPRLGHSGMI 856


>gi|218084958 anoctamin 4 [Homo sapiens]
          Length = 920

 Score =  725 bits (1871), Expect = 0.0
 Identities = 377/869 (43%), Positives = 552/869 (63%), Gaps = 56/869 (6%)

Query: 64  QQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSE 123
           +   + ++FRDG  +ID++L Y     + +  + E+R+ FE N+R  GL++E E    + 
Sbjct: 69  RNKSNGLYFRDGKCRIDYILVY-----RKSNPQTEKREVFERNIRAEGLQMEKESSLINS 123

Query: 124 DGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLG------------- 170
           D    FVK+HAPWEVL  YAE + ++MP +      P+       +              
Sbjct: 124 D--IIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKK 181

Query: 171 PVRLPLSV--KYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIE 228
           P+RL           + +TA FS+ R   F+I ++ TFF +++R+RIV++IL R  +  E
Sbjct: 182 PMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKY--E 239

Query: 229 DGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSE--PPNPTNERYTLHQNWARFSYFYKEQ 286
           +GK + G+ RLL + +Y +A+PLH+G Y   +        N R+ L++ WA +  +YK Q
Sbjct: 240 EGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQ 299

Query: 287 PLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIG 346
           PLDL++ Y+GEKIG+YF +LG+YT MLF AA +GL  F+YG+ +++H+  S E+C     
Sbjct: 300 PLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT-- 357

Query: 347 GQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQAR 406
             +IMCP+CD+ C + RL+ +C+ +K +HLFDN +TVFFA+FM +W T+FLEFWK+R+A 
Sbjct: 358 -DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAV 416

Query: 407 LEYEWDLVDFEEEQQQLQLRPEFEAM-CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATV 465
           + Y+WDL+D+EEE++++  RP+FEA   K  ++N ++ + EPY     +     +S + +
Sbjct: 417 IAYDWDLIDWEEEEEEI--RPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGI 474

Query: 466 TLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVI 525
              + +V+ ++  +++YR+   +TFA+F       K        Q+ T+ T  C+NF +I
Sbjct: 475 FFMICVVIAAVFGIVIYRVVTVSTFAAF-------KWALIRNNSQVATTGTAVCINFCII 527

Query: 526 LILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYP 585
           ++LN  YEK++  +T +E PRT  E+E+S TLKMFLFQFVN  SS FY+AFF G+F G+P
Sbjct: 528 MLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHP 587

Query: 586 GKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKART 645
           G Y  L N WR EEC P GCLI+L  Q+ IIM  KQ + N  E  YPL  NWW RRK R 
Sbjct: 588 GAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQ 647

Query: 646 N---SEKL-YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNI 701
                 K+ + +WE+D++L+     GLF EYLE + QFGF T+FVA+FPLAPLLAL+NNI
Sbjct: 648 EHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNI 707

Query: 702 VEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYY 761
           +EIR+DA+K  TQ+RR +AS+A  IG+W  IL G+ +LSV TNAF++A TSD IPRLVY 
Sbjct: 708 IEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYA 767

Query: 762 YAYSTNATQP------MTGYVNNSLSVFLIADFPNHTAP-SEKRDFI-----TCRYRDYR 809
           Y Y   A Q       M GYVN SLSVF I+DF N + P S+  +F       CRYRDYR
Sbjct: 768 YKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYR 827

Query: 810 YPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKL 869
            PP     Y + +QFWHVLAA++ FIIV EH+VF +K L++++IPD+PKD+ +R++REK 
Sbjct: 828 DPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKY 887

Query: 870 MTIKILHDFELNKL-KENLGINSNEFAKH 897
           +  +++++ EL +L KE      N  A H
Sbjct: 888 LIQEMMYEAELERLQKERKERKKNGKAHH 916


>gi|156766084 transmembrane protein 16C [Homo sapiens]
          Length = 981

 Score =  692 bits (1787), Expect = 0.0
 Identities = 390/897 (43%), Positives = 550/897 (61%), Gaps = 63/897 (7%)

Query: 17  VNKHIDYSFQMSESLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRDG 75
           + K  DY+ +   +   R  S LIN+  +  K  F   L +  M   N  +     F+DG
Sbjct: 106 LGKDKDYTDESEHATYDR--SRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKDG 160

Query: 76  IRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAP 135
            ++ID++L Y     +   ++ ++R  FE NLR  GL LE E    S D    F+KIH P
Sbjct: 161 KKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHIP 213

Query: 136 WEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSVKYPH 182
           W+ L  YAE L I+MP ++        +                    P+ L  S  +P 
Sbjct: 214 WDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSA-FPD 272

Query: 183 PEY---FTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239
            E    +T  FSR R   F+I ++ TFF +++R+RIVY++L R  +  E+G  + GI +L
Sbjct: 273 LEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKL 330

Query: 240 LNSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 296
           +N+ +Y +A+P H+G Y K S+P     P N R+ L++ WAR+  +YK QPLDLI+ Y+G
Sbjct: 331 INNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFG 389

Query: 297 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 356
           EKIG+YF +LG+YT ML  AA+VGL  F YGL +M ++  S EIC      ++ MCPLCD
Sbjct: 390 EKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCD 446

Query: 357 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 416
           + C   RLN +C+ +K ++LFDN  TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++
Sbjct: 447 KNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEW 506

Query: 417 EEEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTS 475
           EEE++ L  RP+FEA   K   +N +T + EP+ P   ++    +S + +   +SLV+T+
Sbjct: 507 EEEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITA 564

Query: 476 MVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKI 535
           +  V+VYRL V   FASF  +   +KQ   F      TS    C+NFI+I++LN  YEKI
Sbjct: 565 VFGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKI 617

Query: 536 SAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEW 595
           +  +T +E PRT  E+E+S  LKMFLFQFVN  SS FY+AFF G+FVG+PGKY  LF+ W
Sbjct: 618 AYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRW 677

Query: 596 RSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRW 654
           R EEC P GCLI+L  Q+ +IM  KQI+ N  E  YPL  NWW R K +    +    +W
Sbjct: 678 RLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQW 737

Query: 655 EQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQ 714
           E D +L+     GL  EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K  TQ
Sbjct: 738 ENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 797

Query: 715 YRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP- 771
           +RR + ++A  IG+W  IL G+ +L+V TNAF++A TSD IPR VY Y Y    N  +P 
Sbjct: 798 WRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPS 857

Query: 772 ---MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVL 828
              + GYVNNSLS F +++     +         CRYRDYR PP     Y   +Q+WH+L
Sbjct: 858 ENCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHIL 910

Query: 829 AAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 885
           AA++ FIIV EH+VF +K  +A++IPDVPK + +RI+REK +  +++++ EL  L++
Sbjct: 911 AARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967


>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
           sapiens]
          Length = 986

 Score =  631 bits (1628), Expect = 0.0
 Identities = 367/925 (39%), Positives = 526/925 (56%), Gaps = 116/925 (12%)

Query: 54  LRRRLMFQKNQQSKDSIFFRDGIRQIDFVLSY-----------------------VDDVK 90
           L   L    + + K  ++FRDG R++D++L Y                          VK
Sbjct: 37  LLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVK 96

Query: 91  KDAEL----------------------KAERRKEFETNLRKTGLELEIEDKRDSEDGRTY 128
           +D  L                      K  RR+E+E NL + GLELE ++  D++     
Sbjct: 97  QDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDE--DTKIHGVG 154

Query: 129 FVKIHAPWEVLVTYAEVLGIKMPIKES---DIPRPKHTPISYVLGPVRLPLSVKYPHPEY 185
           FVKIHAPW VL   AE L +KMP K+    +  R     I+ VL  +  P+  K      
Sbjct: 155 FVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRP 214

Query: 186 FTAQ-----FSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240
            T +     FSR +Q LF + D+ +FF S +R+ IVY IL R        K   GI  LL
Sbjct: 215 QTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT--CTKAKYSMGITSLL 272

Query: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300
            +  Y++AYPLHDG Y   +      N+R  L++ WAR+  FYK QP+DL++ Y+GEKIG
Sbjct: 273 ANGVYAAAYPLHDGDY---NGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIG 329

Query: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360
           +YF +LG YT+ML  A++VG+  F+YG  +M+ N  S E+CD      + MCPLCD+ C 
Sbjct: 330 LYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQR--HNITMCPLCDKTCS 387

Query: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420
           YW+++S C  ++ SHLFDN +TVFF++FM +W   F+E WK++Q RL Y WDL  FEEE+
Sbjct: 388 YWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE 447

Query: 421 QQLQLRP--EFEA--MCKHRKLNAVTKEMEPYMPLYT----------------------- 453
           + ++  P  E+EA  + K  K  +  KE   ++P  +                       
Sbjct: 448 EAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL 507

Query: 454 ----RIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTP 509
               R P Y  +  ++   +++    ++ VI+YR+S+ A  A  M S  S++        
Sbjct: 508 TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA--MNSSPSVRS-----NI 560

Query: 510 QITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYS 569
           ++T + T   +N +VI++L+  Y  I+ W+TK+E+P+T + +E  L  K FL +FVN Y+
Sbjct: 561 RVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYT 620

Query: 570 SCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIF-GNIKE 628
             FYVAFFKG+FVG PG Y Y+F  +R EEC PGGCL+EL  QL+IIM GKQ+   N+ E
Sbjct: 621 PIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFE 680

Query: 629 AIYPLALNWWRRRKARTNSE-------KLYSRWEQDHDLESFGPLGLFYEYLETVTQFGF 681
              P      R  K +  S        K   R+E D++LE F   GL  EY+E + QFGF
Sbjct: 681 IGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGF 738

Query: 682 VTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSV 741
           VTLFVASFPLAPL AL+NNI+EIR+DA K  T+ RR VA +A  IG+W +IL G+  L+V
Sbjct: 739 VTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV 798

Query: 742 ATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF- 800
             NAF+++FTSD IPRLVY Y YS N T  M G+VN++LS F ++DF N TAP++  D  
Sbjct: 799 IINAFVISFTSDFIPRLVYLYMYSKNGT--MHGFVNHTLSSFNVSDFQNGTAPNDPLDLG 856

Query: 801 ---ITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVP 857
                CRY+DYR PP  ENKY  +  FW VLAA++ F+IV +++V  +   + W+IPD+P
Sbjct: 857 YEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIP 916

Query: 858 KDVVERIKREKLMTIKILHDFELNK 882
           KD+ ++I +EK++ +++    E +K
Sbjct: 917 KDISQQIHKEKVLMVELFMREEQDK 941


>gi|209862785 anoctamin 2 [Homo sapiens]
          Length = 998

 Score =  623 bits (1606), Expect = e-178
 Identities = 345/828 (41%), Positives = 499/828 (60%), Gaps = 59/828 (7%)

Query: 94  ELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIK 153
           E + E+R+EFE NL + GLELE +D  +   G + FV+IHAPW+VL   AE L IK+P K
Sbjct: 149 EERKEQREEFEHNLMEAGLELE-KDLENKSQG-SIFVRIHAPWQVLAREAEFLKIKVPTK 206

Query: 154 ES-DIPRPKHTPISYVLGPVRLPLSVKYPHPEY-------FTAQFSRHRQELFLIEDQAT 205
           +  +I         +     +L   ++   PE+        +  FSR +  L+ I+++ T
Sbjct: 207 KMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQEKDT 266

Query: 206 FFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNP 265
           FF +++R+RIV+ IL R            GI  L+ +N Y +AYPLHDG+Y     P + 
Sbjct: 267 FFDNATRSRIVHEILKRT--ACSRANNTMGINSLIANNIYEAAYPLHDGEY---DSPEDD 321

Query: 266 TNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFI 325
            N+R  L+Q WAR+  FYK QP+DLI+ Y+GEKIG+YF +LG YT  L  ++V+G+  F+
Sbjct: 322 MNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFL 381

Query: 326 YGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFF 385
           YG  ++E +  S E+CD +      MCPLCD+ CDYW L+S C  ++ SHLFDN +TVFF
Sbjct: 382 YGCATIEEDIPSREMCDQQ--NAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439

Query: 386 AIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQ--LRPEFEA-----MCKHRKL 438
           +IFM +W T+FLE WK+ Q RL Y WDL   EEE+++ Q   RPE+E      M K    
Sbjct: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499

Query: 439 NAVTK-----------EMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVF 487
           +AV K           + E  +    R P Y ++ A++   ++L  + +  VIVYR++  
Sbjct: 500 SAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRIT-- 557

Query: 488 ATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRT 547
            T A+   + A+   V+      +T + T   +N +VILIL+  Y  ++ W+TK+E+P+T
Sbjct: 558 -TAAALSLNKATRSNVR------VTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKT 610

Query: 548 YQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLI 607
            Q +E  L LK FL +FVN YS  FYVAFFKG+FVG PG Y Y+F+ +R EEC PGGCL+
Sbjct: 611 EQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLM 670

Query: 608 ELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRKARTNS-------EKLYSRWEQDHD 659
           EL  QL+IIM GKQ+   NI E   P     +R+ K  T +        K   +W+ D+ 
Sbjct: 671 ELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYS 730

Query: 660 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 719
           LE +   GL  EY+E + QFGFVTLFVASFPLAP+ AL+NN++E+R+DA K  T+ RR  
Sbjct: 731 LEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPD 788

Query: 720 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 779
           A +   IG+W DIL G+   SV +NAF++A TSD IPRLVY Y+YS N T  + G+VN++
Sbjct: 789 AVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGT--LHGFVNHT 846

Query: 780 LSVFLIADFPNHTAPSEK---RDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFII 836
           LS F ++     T P      ++   CR++DYR PP   N Y  + Q+W +L+A++ F+I
Sbjct: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVI 906

Query: 837 VMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLK 884
           + +++V  +  L+ WMIPD+P D+ ++IK+EK + +      E  KLK
Sbjct: 907 IFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954


>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
           sapiens]
          Length = 933

 Score =  543 bits (1398), Expect = e-154
 Identities = 326/830 (39%), Positives = 482/830 (58%), Gaps = 64/830 (7%)

Query: 77  RQIDFVLSYVDDVKKD----------AELKAERRKEFETNLRKTGLELEIEDKRDSEDGR 126
           R  DFVL + +D+K D           ++    R+ F  NLR  GL +   D++D +DG 
Sbjct: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCV---DQQDVQDGN 164

Query: 127 T--YFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLP--LSVKYPH 182
           T  ++  + A W VL  YAE L +K+P++E  +P       + +L  + +P  L    P 
Sbjct: 165 TTVHYALLSASWAVLCYYAEDLRLKLPLQE--LPNQASNWSAGLLAWLGIPNVLLEVVPD 222

Query: 183 --PEYFTAQFSRHRQELFLIED-QATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239
             PEY++ +F  ++   FL  D Q TFF S+ R++I++ IL++ P+G E  K   GI +L
Sbjct: 223 VPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEK-KNLLGIHQL 281

Query: 240 LNSNTYSSAYPLHDGQYWKPSEPPNPT--NERYTLHQNWARFSYFYKEQPLDLIKNYYGE 297
           L     S+A+PLHDG +  P E P     N+R  L Q+WAR+  + K QPLD ++ Y+GE
Sbjct: 282 LAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGE 341

Query: 298 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 357
           K+ +YF +LGFYT  L  AAVVG   F+ G   +  +  + E+C  +   +M  CPLC  
Sbjct: 342 KVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEM--CPLCLD 399

Query: 358 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 417
            C +W L+S C  ++   LFD+  TVFF++FM +W  L LE+WK++ A L Y WD  D+E
Sbjct: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458

Query: 418 EEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMV 477
           + +++   RP+F A       N +T E EPY P  +R          + + +++VV  +V
Sbjct: 459 DTEERP--RPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLV 516

Query: 478 AVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISA 537
           ++I+YR ++ A   S    +  L    S +      SLTGS +N + ILIL+  Y  ++ 
Sbjct: 517 SIILYR-AIMAIVVS-RSGNTLLAAWASRIA-----SLTGSVVNLVFILILSKIYVSLAH 569

Query: 538 WITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRS 597
            +T+ E+ RT  ++E + TLK+F+FQFVNFYSS  Y+AFFKG+FVGYPG Y  LF   R+
Sbjct: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RN 628

Query: 598 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWW-------RRRKARTNSEKL 650
           EEC  GGCLIEL  +L +IM GKQ+  N++E + P    WW       ++RKA  ++   
Sbjct: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688

Query: 651 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 710
              WE D++L      GLF EYLE V QFGFVT+FVA+ PLAPL AL+NN VEIR+DA K
Sbjct: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746

Query: 711 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQ 770
              +YRR VA +A  IG+W  IL G+  L+V +NAF++AF+SD +PR  Y +        
Sbjct: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW----TRAH 802

Query: 771 PMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAA 830
            + G++N     F +A  P+  A +  R   TCRYR +R   DD+  Y  +  +W++LA 
Sbjct: 803 DLRGFLN-----FTLARAPSSFAAAHNR---TCRYRAFR---DDDGHY--SQTYWNLLAI 849

Query: 831 KMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 880
           ++ F+IV EHVVF V  LL  ++PD+P+ V  ++KRE  +  + L + E+
Sbjct: 850 RLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899


>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
          Length = 782

 Score =  437 bits (1123), Expect = e-122
 Identities = 238/649 (36%), Positives = 365/649 (56%), Gaps = 55/649 (8%)

Query: 237 ERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 296
           E L+    + + +PLH G+                L + WAR+ + ++EQP+D I+NY+G
Sbjct: 139 EDLMKDGVFEARFPLHKGEG--------------RLKKTWARWRHMFREQPVDEIRNYFG 184

Query: 297 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 356
           EK+ +YFV+LG+YT ML  AA+ GL  F+ G    E +  S EIC+      ++MCPL D
Sbjct: 185 EKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAH---DILMCPLGD 241

Query: 357 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 416
               Y RL+ TC  +K +HLFDN+ TV FAIFM +W T+FLE WK+++AR+   WDL  +
Sbjct: 242 HSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVW 301

Query: 417 EEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSM 476
           +EEQ+++ L+           +N    ++ PY   Y R        +TV L ++L++  +
Sbjct: 302 DEEQEEMALQ----------LINCPDYKLRPYQHSYLR--------STVILVLTLLMICL 343

Query: 477 VAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSL--TGSCLNFIVILILNFFYEK 534
           +  + + L V+   AS + S +++     FL  Q+TT++  TG+ ++++ I+I+      
Sbjct: 344 MIGMAHVLVVYRVLASALFSSSAVP----FLEEQVTTAVVVTGALVHYVTIIIMTKINRC 399

Query: 535 ISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNE 594
           ++  +   E+PRT+ E ES  T++ F  QF   +SS  Y+AF  G+  G+PGK T L   
Sbjct: 400 VALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGL 459

Query: 595 WRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNS----EKL 650
           W+ EEC   GC+++L  Q+ IIM  KQ   N  E + P   +  R  +A  +     +  
Sbjct: 460 WKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPE 519

Query: 651 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 710
              W +++ L       LF E++E + Q+GF T+FVA+FPLAPLLAL +N+VEIR+DA K
Sbjct: 520 LRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIK 579

Query: 711 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS----- 765
           +    RR V  KA  IG W  +L  + VL+V  N  ++AFTS+ IPR+VY Y YS     
Sbjct: 580 MVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKE 639

Query: 766 -TNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQF 824
             +    + GYVN+SLSVF   DF +        +   CRYRDYR PPD    Y  + QF
Sbjct: 640 GNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPD----YNFSEQF 695

Query: 825 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIK 873
           W +LA ++ F+I+ EHV   +K + AW +PD+P+ V  ++   K   ++
Sbjct: 696 WFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLR 744


>gi|94536803 transmembrane protein 16K [Homo sapiens]
          Length = 660

 Score =  153 bits (386), Expect = 8e-37
 Identities = 138/531 (25%), Positives = 218/531 (41%), Gaps = 120/531 (22%)

Query: 236 IERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNW-ARFSYFYKEQPLDLIKNY 294
           + RLL S      +PLHD +  K             L   W  RF+  Y  QP+D I+ Y
Sbjct: 158 LRRLLTSGIVIQVFPLHDSEALKK------------LEDTWYTRFALKY--QPIDSIRGY 203

Query: 295 YGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPL 354
           +GE I +YF FL ++T  L   AV+GL  +++                            
Sbjct: 204 FGETIALYFGFLEYFTFALIPMAVIGLPYYLF---------------------------- 235

Query: 355 CDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLV 414
                  W               D +  V FA F  IW T+ LE WK+  A + Y W  +
Sbjct: 236 ------VWE--------------DYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTL 275

Query: 415 DFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTR-IPWYFLSGATVTLWMSLVV 473
             + + ++   RP F  +     +N++T + EP  P Y R +  Y +S   V L   L  
Sbjct: 276 LMKRKFEEP--RPGFHGVLG---INSITGKEEPLYPSYKRQLRIYLVSLPFVCL--CLYF 328

Query: 474 TSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYE 533
           +  V +I + + V+A      E+  S         P I  +        IVI I+N  Y 
Sbjct: 329 SLYVMMIYFDMEVWAL--GLHENSGSEWTSVLLYVPSIIYA--------IVIEIMNRLYR 378

Query: 534 KISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFN 593
             + ++T  E  R    Y++ L LK+ +F F+N ++S FY+AF              +  
Sbjct: 379 YAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAF--------------VLK 424

Query: 594 EWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSR 653
           + +            L   L  ++   QI   I E+  P    +W +RK     ++    
Sbjct: 425 DMKL-----------LRQSLATLLITSQILNQIMESFLP----YWLQRKHGVRVKRKVQA 469

Query: 654 WEQDHDLESFGP----------LGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVE 703
            + D D   +            LG F +YLE   QFG+V+LF   +PLA   A++NN  E
Sbjct: 470 LKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTE 529

Query: 704 IRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDI 754
           +  DA K+   ++R  +  + +IGVWQ     M+V+SV TN  ++  +  +
Sbjct: 530 VNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQV 580



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 18/67 (26%), Positives = 37/67 (55%)

Query: 821 NMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 880
           N  F    A  +  ++ +EH +  +KF+LA+ IPD P+ +  ++ R +  +++ L   ++
Sbjct: 581 NAVFPESKADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQM 640

Query: 881 NKLKENL 887
             + ENL
Sbjct: 641 KLVTENL 647


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score =  110 bits (276), Expect = 5e-24
 Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 85/385 (22%)

Query: 200 IEDQATFFPSSSRNRIVYYILS--RCPFGIEDGKKRFG-----IERLLNSNTYSSAYPLH 252
           +E +  FF S  R  I+ + L   R   G      RF      I  L         +P+H
Sbjct: 153 VESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVH 212

Query: 253 DGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEM 312
           + +                L ++W +     + QPLD I +Y+G KI +YF +LGFYT  
Sbjct: 213 EQRILN------------RLMKSWVQA--VCENQPLDDICDYFGVKIAMYFAWLGFYTSA 258

Query: 313 LFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASK 372
           + + AV G   + +     E + +S ++                                
Sbjct: 259 MVYPAVFGSVLYTF----TEADQTSRDV-------------------------------- 282

Query: 373 FSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAM 432
                   S V FA+F  IW TLFLE WK+R A L Y+W  +D   E  + + RP+F  +
Sbjct: 283 --------SCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVE-EPRPQFRGV 333

Query: 433 CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFAS 492
              R+++ +T+  E Y P + R+ +  L        + L +  +V V +  L  F     
Sbjct: 334 ---RRISPITRAEEFYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQ-LQE 383

Query: 493 FMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 552
            + S   L ++  FL P++  +L        ++ +    Y+K++ W+  ME  R    YE
Sbjct: 384 LVLSVKGLPRLARFL-PKVMLAL--------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434

Query: 553 SSLTLKMFLFQFVNFYSSCFYVAFF 577
             L +K+ LFQFVN Y S FY+ F+
Sbjct: 435 KHLIIKVVLFQFVNSYLSLFYIGFY 459



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 9/118 (7%)

Query: 640 RRKARTNSEKLYSRWEQDH-------DLESFGPL--GLFYEYLETVTQFGFVTLFVASFP 690
           RR+ R N        E++H       +LES        F +Y E   QFG+V LF ++FP
Sbjct: 707 RRQRRQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFP 766

Query: 691 LAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIV 748
           LA L AL+NN++EIR DA+KL T  +R    +  SIG WQ ++  M VL++  N +++
Sbjct: 767 LAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 825 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKR 866
           W    A +  ++V+EH   L+K+L+   IPD+P  V E + +
Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAK 877


>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 494

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 44/130 (33%), Positives = 64/130 (49%), Gaps = 31/130 (23%)

Query: 598 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQD 657
           ++C PGGC I++T QL IIM GKQ+  +++E +                           
Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV--------------------------- 263

Query: 658 HDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRR 717
                 G  G     L  + QFGF+T+FV +F LAPL  L+NN VEI +DA K   +Y+R
Sbjct: 264 ---GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQR 319

Query: 718 TVASKAHSIG 727
            +A +  + G
Sbjct: 320 PMAGRGWTSG 329



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 34/163 (20%)

Query: 372 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 420
           K S LFD+  TVFF+IFM  W        +   A L + WD  DF++++           
Sbjct: 50  KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 109

Query: 421 ----QQLQLRP---------------EFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLS 461
               Q  ++ P               EF A+      N VT   EPY   ++ +     S
Sbjct: 110 CSDFQDQEVMPSSALHHWDCSDFQDQEFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTS 169

Query: 462 GATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500
            A +   + +V+  +V+VI+Y     +++F T  S + + A++
Sbjct: 170 SAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 212


>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 723

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%)

Query: 599 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 658
           +C PGGC I++T QL IIM GKQ+  +++E +                            
Sbjct: 461 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 492

Query: 659 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 718
                G  G     L  + QFGF+T+FV +F LAPL  L+NN VEI +DA K   +Y+R 
Sbjct: 493 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 549

Query: 719 VASKAHSIG 727
           +A +  + G
Sbjct: 550 MAGRGWTSG 558



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 37/165 (22%), Positives = 65/165 (39%), Gaps = 40/165 (24%)

Query: 376 LFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ--------------- 420
           L D   TVFF+IFM  W        +   A L + WD  DF++++               
Sbjct: 262 LGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDF 321

Query: 421 QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYF 459
           Q  ++ P                     +F A+      N VT   EPY   ++ +    
Sbjct: 322 QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLL 381

Query: 460 LSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500
            S A +   + +V+  +V+VI+Y     +++F T  S + + A++
Sbjct: 382 TSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 426


>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 719

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%)

Query: 599 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 658
           +C PGGC I++T QL IIM GKQ+  +++E +                            
Sbjct: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 488

Query: 659 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 718
                G  G     L  + QFGF+T+FV +F LAPL  L+NN VEI +DA K   +Y+R 
Sbjct: 489 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 545

Query: 719 VASKAHSIG 727
           +A +  + G
Sbjct: 546 MAGRGWTSG 554



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 40/169 (23%)

Query: 372 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 420
           K S LFD+  TVFF+IFM  W        +   A L + WD  DF++++           
Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313

Query: 421 ----QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRI 455
               Q  ++ P                     +F A+      N VT   EPY   ++ +
Sbjct: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCL 373

Query: 456 PWYFLSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500
                S A +   + +V+  +V+VI+Y     +++F T  S + + A++
Sbjct: 374 SHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 422


>gi|22748943 hypothetical protein LOC145483 [Homo sapiens]
          Length = 647

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 403 RQARLEYEW--DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRI 455
           R+AR + EW      FE+E+Q+ Q + E EA C HR+  A       Y+PLY  I
Sbjct: 180 REARKKAEWLGSPASFEQERQRAQRQGEEEAEC-HRQFRAQPVPAHVYLPLYQEI 233


>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
          Length = 2459

 Score = 33.5 bits (75), Expect = 0.93
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 15/135 (11%)

Query: 445  MEPYMPLYT---RIPWYFLSGATVTLWMSLVVTSMVAVIVY--RLSVFATFASFMESDAS 499
            + P M + T   R  W  +SG  + +   L+  S+ + +++  +L  + T     E+  S
Sbjct: 2293 LNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVS 2352

Query: 500  LK-------QVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 552
            L+       +V  + +P + + L GSC+ F+  ++LN F   I   +   E  + YQ  E
Sbjct: 2353 LQLGIFNYEEVLDY-SPVLGSFLIGSCIVFMTFVVLNLFISVI--LVAFSEEQKYYQLSE 2409

Query: 553  SSLTLKMFLFQFVNF 567
                + + L + ++F
Sbjct: 2410 EGEIVDLLLMKILSF 2424


>gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens]
          Length = 925

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 451 LYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLT-- 508
           LY ++       A +T+    V +    V+ Y+         F  +   + Q K  L   
Sbjct: 140 LYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRL 199

Query: 509 PQITTSLTGSCLNFIVILILNFFYEKISAWITK 541
           PQ+T+SL   C NF V    N  YE+ S W+++
Sbjct: 200 PQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQ 232


>gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens]
          Length = 940

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 451 LYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLT-- 508
           LY ++       A +T+    V +    V+ Y+         F  +   + Q K  L   
Sbjct: 155 LYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRL 214

Query: 509 PQITTSLTGSCLNFIVILILNFFYEKISAWITK 541
           PQ+T+SL   C NF V    N  YE+ S W+++
Sbjct: 215 PQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQ 247


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 858 KDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMIEENKAQ 906
           K  + R+++E+  T+  L D+E       LG+ SNE   H++  E K Q
Sbjct: 195 KSYLWRLEKEEQQTLSRLRDYEAG-----LGLKSNELKSHILELEEKCQ 238


>gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens]
          Length = 300

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 593 NEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLA 634
           N W ++ C  G C+++L+  L I   GK +F   K+A +P +
Sbjct: 111 NTWSAQNCKNGSCVLDLSKCLFI--QGKLLFAEPKDAGFPFS 150


>gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens]
          Length = 300

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 593 NEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLA 634
           N W ++ C  G C+++L+  L I   GK +F   K+A +P +
Sbjct: 111 NTWSAQNCKNGSCVLDLSKCLFI--QGKLLFAEPKDAGFPFS 150


>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
          Length = 4588

 Score = 30.8 bits (68), Expect = 6.0
 Identities = 28/148 (18%), Positives = 64/148 (43%), Gaps = 21/148 (14%)

Query: 82   VLSYVDDVKKDAELKAERRKEFETNLRKTGLE---LEIEDKRDSEDGRTYFVKIHAPWEV 138
            V ++ +D ++D E++   R      + K G E   +E  D+ D E    Y++ + A  + 
Sbjct: 1056 VSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQG 1115

Query: 139  LVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKYPHPEYFTAQFSRHRQELF 198
            +V  +  + I + +++ +   P+ +                   P Y+        +++ 
Sbjct: 1116 VVPLSSFIEIYIEVEDVNDNAPQTS------------------EPVYYPEIMENSPKDVS 1157

Query: 199  LIEDQATFFPSSSRNRIVYYILSRCPFG 226
            +++ +A    SSS ++++Y I S  P G
Sbjct: 1158 VVQIEAFDPDSSSNDKLMYKITSGNPQG 1185


>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
           sapiens]
          Length = 1719

 Score = 30.8 bits (68), Expect = 6.0
 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 7/124 (5%)

Query: 7   LEVLAEEGEKVNKHIDYSFQMSESLS--SRETSFLINEETMPAKRFNLFLRRRLMFQKNQ 64
           ++ L +E E +NK +    Q SE L   S+E      +  +  + F + +  RL     Q
Sbjct: 537 IKTLQQEREDLNKEL---VQASERLKNQSKELKDAHCQRKLAMQEF-MEINERLTELHTQ 592

Query: 65  QSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSED 124
           + K +   RD   ++D V+  V+ ++++       +KE E +      E   +D++  E 
Sbjct: 593 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEAS-KDRKLREQ 651

Query: 125 GRTY 128
              Y
Sbjct: 652 SEHY 655


>gi|44955929 calmodulin regulated spectrin-associated protein 1-like 1
            [Homo sapiens]
          Length = 1478

 Score = 30.8 bits (68), Expect = 6.0
 Identities = 16/39 (41%), Positives = 24/39 (61%)

Query: 89   VKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRT 127
            +K+ A L+   R+E ET LRK  LE E+E K++    +T
Sbjct: 1166 MKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKT 1204


>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
           sapiens]
          Length = 402

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%)

Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712
           RWE    ++  G L  F+    T+T FG  +LF+AS         +   + IR   W   
Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165

Query: 713 TQYRRTVASKAHSIGVWQDIL 733
             + +T A++A  +GVW  +L
Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186


>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
           sapiens]
          Length = 388

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%)

Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712
           RWE    ++  G L  F+    T+T FG  +LF+AS         +   + IR   W   
Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165

Query: 713 TQYRRTVASKAHSIGVWQDIL 733
             + +T A++A  +GVW  +L
Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186


>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
           sapiens]
          Length = 390

 Score = 30.4 bits (67), Expect = 7.8
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%)

Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712
           RWE    ++  G L  F+    T+T FG  +LF+AS         +   + IR   W   
Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165

Query: 713 TQYRRTVASKAHSIGVWQDIL 733
             + +T A++A  +GVW  +L
Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,072,605
Number of Sequences: 37866
Number of extensions: 1458583
Number of successful extensions: 4819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 4667
Number of HSP's gapped (non-prelim): 72
length of query: 912
length of database: 18,247,518
effective HSP length: 111
effective length of query: 801
effective length of database: 14,044,392
effective search space: 11249557992
effective search space used: 11249557992
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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