BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|218081589 anoctamin 5 isoform b [Homo sapiens] (912 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|218081589 anoctamin 5 isoform b [Homo sapiens] 1862 0.0 gi|47106048 anoctamin 5 isoform a [Homo sapiens] 1857 0.0 gi|218156303 anoctamin 6 isoform b [Homo sapiens] 880 0.0 gi|218156299 anoctamin 6 isoform a [Homo sapiens] 880 0.0 gi|218156307 anoctamin 6 isoform c [Homo sapiens] 837 0.0 gi|218156305 anoctamin 6 isoform c [Homo sapiens] 837 0.0 gi|218084958 anoctamin 4 [Homo sapiens] 725 0.0 gi|156766084 transmembrane protein 16C [Homo sapiens] 692 0.0 gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 631 0.0 gi|209862785 anoctamin 2 [Homo sapiens] 623 e-178 gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 543 e-154 gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 437 e-122 gi|94536803 transmembrane protein 16K [Homo sapiens] 153 8e-37 gi|55741655 anoctamin 8 [Homo sapiens] 110 5e-24 gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 67 8e-11 gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 66 1e-10 gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 66 1e-10 gi|22748943 hypothetical protein LOC145483 [Homo sapiens] 37 0.084 gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 33 0.93 gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens] 32 2.7 gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens] 32 2.7 gi|5454014 tripartite motif-containing 38 [Homo sapiens] 31 4.6 gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens] 31 4.6 gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens] 31 4.6 gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 31 6.0 gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 31 6.0 gi|44955929 calmodulin regulated spectrin-associated protein 1-l... 31 6.0 gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 30 7.8 gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 30 7.8 gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 30 7.8 >gi|218081589 anoctamin 5 isoform b [Homo sapiens] Length = 912 Score = 1862 bits (4823), Expect = 0.0 Identities = 912/912 (100%), Positives = 912/912 (100%) Query: 1 MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF 60 MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF Sbjct: 1 MGDPDLLEVLAEEGEKVNKHIDYSFQMSESLSSRETSFLINEETMPAKRFNLFLRRRLMF 60 Query: 61 QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR 120 QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR Sbjct: 61 QKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKR 120 Query: 121 DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY 180 DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY Sbjct: 121 DSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKY 180 Query: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL Sbjct: 181 PHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240 Query: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG Sbjct: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300 Query: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD Sbjct: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360 Query: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ Sbjct: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420 Query: 421 QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI 480 QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI Sbjct: 421 QQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVI 480 Query: 481 VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT 540 VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT Sbjct: 481 VYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWIT 540 Query: 541 KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC 600 KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC Sbjct: 541 KMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEEC 600 Query: 601 DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL 660 DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL Sbjct: 601 DPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDL 660 Query: 661 ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA 720 ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA Sbjct: 661 ESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVA 720 Query: 721 SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL 780 SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL Sbjct: 721 SKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSL 780 Query: 781 SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH 840 SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH Sbjct: 781 SVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEH 840 Query: 841 VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI 900 VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI Sbjct: 841 VVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMI 900 Query: 901 EENKAQLAKSTL 912 EENKAQLAKSTL Sbjct: 901 EENKAQLAKSTL 912 >gi|47106048 anoctamin 5 isoform a [Homo sapiens] Length = 913 Score = 1857 bits (4811), Expect = 0.0 Identities = 912/913 (99%), Positives = 912/913 (99%), Gaps = 1/913 (0%) Query: 1 MGDPDLLEVLAEEGEKVNKHIDYSFQMSE-SLSSRETSFLINEETMPAKRFNLFLRRRLM 59 MGDPDLLEVLAEEGEKVNKHIDYSFQMSE SLSSRETSFLINEETMPAKRFNLFLRRRLM Sbjct: 1 MGDPDLLEVLAEEGEKVNKHIDYSFQMSEQSLSSRETSFLINEETMPAKRFNLFLRRRLM 60 Query: 60 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK 119 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK Sbjct: 61 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDK 120 Query: 120 RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK 179 RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK Sbjct: 121 RDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVK 180 Query: 180 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL Sbjct: 181 YPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 240 Query: 240 LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI 299 LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI Sbjct: 241 LNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKI 300 Query: 300 GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC 359 GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC Sbjct: 301 GIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVC 360 Query: 360 DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE 419 DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE Sbjct: 361 DYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEE 420 Query: 420 QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV 479 QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV Sbjct: 421 QQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAV 480 Query: 480 IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI 539 IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI Sbjct: 481 IVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWI 540 Query: 540 TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE 599 TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE Sbjct: 541 TKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEE 600 Query: 600 CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD 659 CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD Sbjct: 601 CDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHD 660 Query: 660 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 719 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV Sbjct: 661 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 720 Query: 720 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 779 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS Sbjct: 721 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 780 Query: 780 LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME 839 LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME Sbjct: 781 LSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVME 840 Query: 840 HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM 899 HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM Sbjct: 841 HVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVM 900 Query: 900 IEENKAQLAKSTL 912 IEENKAQLAKSTL Sbjct: 901 IEENKAQLAKSTL 913 >gi|218156303 anoctamin 6 isoform b [Homo sapiens] Length = 892 Score = 880 bits (2275), Expect = 0.0 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%) Query: 60 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113 F++ DS+FF DG R+IDFVL Y D+ +K+ K +R+ +E+NL GL+ Sbjct: 32 FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 91 Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171 LE R D + FVK+HAPWEVL TYAE++ IK+P+K +D+ +++ Sbjct: 92 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 149 Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231 + + S+ P E+FTA F ++R F I D+ FF ++R+RIVY+ILSR + + + Sbjct: 150 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 209 Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291 +FGI RL+NS Y +A+PLHD ++ + SE P+ NERY L++ WA YK+QPLDLI Sbjct: 210 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 269 Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351 + YYGEKIGIYF +LG+YT+ML AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM Sbjct: 270 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 329 Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411 CP CD++C +W+LN TC +SK +FD+ T+ FA+FMG+WVTLFLEFWK+RQA LEYEW Sbjct: 330 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 389 Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463 D V+ ++E+Q RPE+EA C H +N +T+E E RIP+ L + Sbjct: 390 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 439 Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522 V W+ L++ S++ +IVYRLSVF F++ + + + ++ +LTPQ TS+T S ++F Sbjct: 440 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 499 Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582 I+I+ILN YEK++ IT E+PRT +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV Sbjct: 500 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 559 Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642 GYPG Y ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P +N R Sbjct: 560 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 619 Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702 + SEK+ RWEQD+ L+ G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+ Sbjct: 620 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 679 Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762 EIRVDAWKLTTQ+RR V KA IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+ Sbjct: 680 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 739 Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814 ++S + + M GY+NN+LS+F +ADF N + + D TCRYRD+RYPP Sbjct: 740 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 799 Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 874 +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K +I+REK +T K+ Sbjct: 800 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 859 Query: 875 LHDFELNKLKENLGI 889 LH+ L + +N+G+ Sbjct: 860 LHENHLKDMTKNMGV 874 >gi|218156299 anoctamin 6 isoform a [Homo sapiens] Length = 910 Score = 880 bits (2275), Expect = 0.0 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%) Query: 60 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113 F++ DS+FF DG R+IDFVL Y D+ +K+ K +R+ +E+NL GL+ Sbjct: 50 FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109 Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171 LE R D + FVK+HAPWEVL TYAE++ IK+P+K +D+ +++ Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167 Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231 + + S+ P E+FTA F ++R F I D+ FF ++R+RIVY+ILSR + + + Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227 Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291 +FGI RL+NS Y +A+PLHD ++ + SE P+ NERY L++ WA YK+QPLDLI Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287 Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351 + YYGEKIGIYF +LG+YT+ML AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347 Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411 CP CD++C +W+LN TC +SK +FD+ T+ FA+FMG+WVTLFLEFWK+RQA LEYEW Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407 Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463 D V+ ++E+Q RPE+EA C H +N +T+E E RIP+ L + Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457 Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522 V W+ L++ S++ +IVYRLSVF F++ + + + ++ +LTPQ TS+T S ++F Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517 Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582 I+I+ILN YEK++ IT E+PRT +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577 Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642 GYPG Y ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P +N R Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637 Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702 + SEK+ RWEQD+ L+ G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+ Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697 Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762 EIRVDAWKLTTQ+RR V KA IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+ Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757 Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814 ++S + + M GY+NN+LS+F +ADF N + + D TCRYRD+RYPP Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817 Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 874 +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K +I+REK +T K+ Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 877 Query: 875 LHDFELNKLKENLGI 889 LH+ L + +N+G+ Sbjct: 878 LHENHLKDMTKNMGV 892 >gi|218156307 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 837 bits (2162), Expect = 0.0 Identities = 417/819 (50%), Positives = 569/819 (69%), Gaps = 37/819 (4%) Query: 60 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113 F++ DS+FF DG R+IDFVL Y D+ +K+ K +R+ +E+NL GL+ Sbjct: 50 FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109 Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171 LE R D + FVK+HAPWEVL TYAE++ IK+P+K +D+ +++ Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167 Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231 + + S+ P E+FTA F ++R F I D+ FF ++R+RIVY+ILSR + + + Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227 Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291 +FGI RL+NS Y +A+PLHD ++ + SE P+ NERY L++ WA YK+QPLDLI Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287 Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351 + YYGEKIGIYF +LG+YT+ML AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347 Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411 CP CD++C +W+LN TC +SK +FD+ T+ FA+FMG+WVTLFLEFWK+RQA LEYEW Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407 Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463 D V+ ++E+Q RPE+EA C H +N +T+E E RIP+ L + Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457 Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522 V W+ L++ S++ +IVYRLSVF F++ + + + ++ +LTPQ TS+T S ++F Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517 Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582 I+I+ILN YEK++ IT E+PRT +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577 Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642 GYPG Y ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P +N R Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637 Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702 + SEK+ RWEQD+ L+ G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+ Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697 Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762 EIRVDAWKLTTQ+RR V KA IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+ Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757 Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814 ++S + + M GY+NN+LS+F +ADF N + + D TCRYRD+RYPP Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817 Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMI 853 +Y HN+ +WHV+AAK+ FIIVME++ L + + MI Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEYLALLPRLGHSGMI 856 >gi|218156305 anoctamin 6 isoform c [Homo sapiens] Length = 929 Score = 837 bits (2162), Expect = 0.0 Identities = 417/819 (50%), Positives = 569/819 (69%), Gaps = 37/819 (4%) Query: 60 FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113 F++ DS+FF DG R+IDFVL Y D+ +K+ K +R+ +E+NL GL+ Sbjct: 50 FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 109 Query: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171 LE R D + FVK+HAPWEVL TYAE++ IK+P+K +D+ +++ Sbjct: 110 LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 167 Query: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231 + + S+ P E+FTA F ++R F I D+ FF ++R+RIVY+ILSR + + + Sbjct: 168 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 227 Query: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291 +FGI RL+NS Y +A+PLHD ++ + SE P+ NERY L++ WA YK+QPLDLI Sbjct: 228 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 287 Query: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351 + YYGEKIGIYF +LG+YT+ML AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM Sbjct: 288 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 347 Query: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411 CP CD++C +W+LN TC +SK +FD+ T+ FA+FMG+WVTLFLEFWK+RQA LEYEW Sbjct: 348 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 407 Query: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463 D V+ ++E+Q RPE+EA C H +N +T+E E RIP+ L + Sbjct: 408 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 457 Query: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522 V W+ L++ S++ +IVYRLSVF F++ + + + ++ +LTPQ TS+T S ++F Sbjct: 458 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 517 Query: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582 I+I+ILN YEK++ IT E+PRT +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV Sbjct: 518 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 577 Query: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642 GYPG Y ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P +N R Sbjct: 578 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 637 Query: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702 + SEK+ RWEQD+ L+ G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+ Sbjct: 638 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 697 Query: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762 EIRVDAWKLTTQ+RR V KA IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+ Sbjct: 698 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 757 Query: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814 ++S + + M GY+NN+LS+F +ADF N + + D TCRYRD+RYPP Sbjct: 758 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 817 Query: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMI 853 +Y HN+ +WHV+AAK+ FIIVME++ L + + MI Sbjct: 818 PQEYKHNIYYWHVIAAKLAFIIVMEYLALLPRLGHSGMI 856 >gi|218084958 anoctamin 4 [Homo sapiens] Length = 920 Score = 725 bits (1871), Expect = 0.0 Identities = 377/869 (43%), Positives = 552/869 (63%), Gaps = 56/869 (6%) Query: 64 QQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSE 123 + + ++FRDG +ID++L Y + + + E+R+ FE N+R GL++E E + Sbjct: 69 RNKSNGLYFRDGKCRIDYILVY-----RKSNPQTEKREVFERNIRAEGLQMEKESSLINS 123 Query: 124 DGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLG------------- 170 D FVK+HAPWEVL YAE + ++MP + P+ + Sbjct: 124 D--IIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKK 181 Query: 171 PVRLPLSV--KYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIE 228 P+RL + +TA FS+ R F+I ++ TFF +++R+RIV++IL R + E Sbjct: 182 PMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKY--E 239 Query: 229 DGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSE--PPNPTNERYTLHQNWARFSYFYKEQ 286 +GK + G+ RLL + +Y +A+PLH+G Y + N R+ L++ WA + +YK Q Sbjct: 240 EGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQ 299 Query: 287 PLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIG 346 PLDL++ Y+GEKIG+YF +LG+YT MLF AA +GL F+YG+ +++H+ S E+C Sbjct: 300 PLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT-- 357 Query: 347 GQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQAR 406 +IMCP+CD+ C + RL+ +C+ +K +HLFDN +TVFFA+FM +W T+FLEFWK+R+A Sbjct: 358 -DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAV 416 Query: 407 LEYEWDLVDFEEEQQQLQLRPEFEAM-CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATV 465 + Y+WDL+D+EEE++++ RP+FEA K ++N ++ + EPY + +S + + Sbjct: 417 IAYDWDLIDWEEEEEEI--RPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGI 474 Query: 466 TLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVI 525 + +V+ ++ +++YR+ +TFA+F K Q+ T+ T C+NF +I Sbjct: 475 FFMICVVIAAVFGIVIYRVVTVSTFAAF-------KWALIRNNSQVATTGTAVCINFCII 527 Query: 526 LILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYP 585 ++LN YEK++ +T +E PRT E+E+S TLKMFLFQFVN SS FY+AFF G+F G+P Sbjct: 528 MLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHP 587 Query: 586 GKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKART 645 G Y L N WR EEC P GCLI+L Q+ IIM KQ + N E YPL NWW RRK R Sbjct: 588 GAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQ 647 Query: 646 N---SEKL-YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNI 701 K+ + +WE+D++L+ GLF EYLE + QFGF T+FVA+FPLAPLLAL+NNI Sbjct: 648 EHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNI 707 Query: 702 VEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYY 761 +EIR+DA+K TQ+RR +AS+A IG+W IL G+ +LSV TNAF++A TSD IPRLVY Sbjct: 708 IEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYA 767 Query: 762 YAYSTNATQP------MTGYVNNSLSVFLIADFPNHTAP-SEKRDFI-----TCRYRDYR 809 Y Y A Q M GYVN SLSVF I+DF N + P S+ +F CRYRDYR Sbjct: 768 YKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYR 827 Query: 810 YPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKL 869 PP Y + +QFWHVLAA++ FIIV EH+VF +K L++++IPD+PKD+ +R++REK Sbjct: 828 DPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKY 887 Query: 870 MTIKILHDFELNKL-KENLGINSNEFAKH 897 + +++++ EL +L KE N A H Sbjct: 888 LIQEMMYEAELERLQKERKERKKNGKAHH 916 >gi|156766084 transmembrane protein 16C [Homo sapiens] Length = 981 Score = 692 bits (1787), Expect = 0.0 Identities = 390/897 (43%), Positives = 550/897 (61%), Gaps = 63/897 (7%) Query: 17 VNKHIDYSFQMSESLSSRETSFLINEETMPAK-RFNLFLRRRLMFQKNQQSKDSIFFRDG 75 + K DY+ + + R S LIN+ + K F L + M N + F+DG Sbjct: 106 LGKDKDYTDESEHATYDR--SRLINDFVIKDKSEFKTKLSKNDM---NYIASSGPLFKDG 160 Query: 76 IRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAP 135 ++ID++L Y + ++ ++R FE NLR GL LE E S D F+KIH P Sbjct: 161 KKRIDYILVY-----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPD--IMFIKIHIP 213 Query: 136 WEVLVTYAEVLGIKMPIKESDIPRPKHTPIS-------------YVLGPVRLPLSVKYPH 182 W+ L YAE L I+MP ++ + P+ L S +P Sbjct: 214 WDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSA-FPD 272 Query: 183 PEY---FTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239 E +T FSR R F+I ++ TFF +++R+RIVY++L R + E+G + GI +L Sbjct: 273 LEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKY--ENGISKVGIRKL 330 Query: 240 LNSNTYSSAYPLHDGQYWKPSEP---PNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 296 +N+ +Y +A+P H+G Y K S+P P N R+ L++ WAR+ +YK QPLDLI+ Y+G Sbjct: 331 INNGSYIAAFPPHEGAY-KSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFG 389 Query: 297 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 356 EKIG+YF +LG+YT ML AA+VGL F YGL +M ++ S EIC ++ MCPLCD Sbjct: 390 EKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVFMCPLCD 446 Query: 357 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 416 + C RLN +C+ +K ++LFDN TVFFAIFM IW T+FLEFWK+R++ L Y WDL+++ Sbjct: 447 KNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEW 506 Query: 417 EEEQQQLQLRPEFEAMC-KHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTS 475 EEE++ L RP+FEA K +N +T + EP+ P ++ +S + + +SLV+T+ Sbjct: 507 EEEEETL--RPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITA 564 Query: 476 MVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKI 535 + V+VYRL V FASF + +KQ F TS C+NFI+I++LN YEKI Sbjct: 565 VFGVVVYRLVVMEQFASFKWN--FIKQYWQF-----ATSAAAVCINFIIIMLLNLAYEKI 617 Query: 536 SAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEW 595 + +T +E PRT E+E+S LKMFLFQFVN SS FY+AFF G+FVG+PGKY LF+ W Sbjct: 618 AYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRW 677 Query: 596 RSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTN-SEKLYSRW 654 R EEC P GCLI+L Q+ +IM KQI+ N E YPL NWW R K + + +W Sbjct: 678 RLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDASIPQW 737 Query: 655 EQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQ 714 E D +L+ GL EYLE V QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ Sbjct: 738 ENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 797 Query: 715 YRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS--TNATQP- 771 +RR + ++A IG+W IL G+ +L+V TNAF++A TSD IPR VY Y Y N +P Sbjct: 798 WRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPS 857 Query: 772 ---MTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVL 828 + GYVNNSLS F +++ + CRYRDYR PP Y +Q+WH+L Sbjct: 858 ENCLKGYVNNSLSFFDLSELGMGKSG-------YCRYRDYRGPPWSSKPYEFTLQYWHIL 910 Query: 829 AAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKE 885 AA++ FIIV EH+VF +K +A++IPDVPK + +RI+REK + +++++ EL L++ Sbjct: 911 AARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQ 967 >gi|194306539 anoctamin 1, calcium activated chloride channel [Homo sapiens] Length = 986 Score = 631 bits (1628), Expect = 0.0 Identities = 367/925 (39%), Positives = 526/925 (56%), Gaps = 116/925 (12%) Query: 54 LRRRLMFQKNQQSKDSIFFRDGIRQIDFVLSY-----------------------VDDVK 90 L L + + K ++FRDG R++D++L Y VK Sbjct: 37 LLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVK 96 Query: 91 KDAEL----------------------KAERRKEFETNLRKTGLELEIEDKRDSEDGRTY 128 +D L K RR+E+E NL + GLELE ++ D++ Sbjct: 97 QDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDE--DTKIHGVG 154 Query: 129 FVKIHAPWEVLVTYAEVLGIKMPIKES---DIPRPKHTPISYVLGPVRLPLSVKYPHPEY 185 FVKIHAPW VL AE L +KMP K+ + R I+ VL + P+ K Sbjct: 155 FVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRP 214 Query: 186 FTAQ-----FSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLL 240 T + FSR +Q LF + D+ +FF S +R+ IVY IL R K GI LL Sbjct: 215 QTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT--CTKAKYSMGITSLL 272 Query: 241 NSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIG 300 + Y++AYPLHDG Y + N+R L++ WAR+ FYK QP+DL++ Y+GEKIG Sbjct: 273 ANGVYAAAYPLHDGDY---NGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIG 329 Query: 301 IYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCD 360 +YF +LG YT+ML A++VG+ F+YG +M+ N S E+CD + MCPLCD+ C Sbjct: 330 LYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQR--HNITMCPLCDKTCS 387 Query: 361 YWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ 420 YW+++S C ++ SHLFDN +TVFF++FM +W F+E WK++Q RL Y WDL FEEE+ Sbjct: 388 YWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE 447 Query: 421 QQLQLRP--EFEA--MCKHRKLNAVTKEMEPYMPLYT----------------------- 453 + ++ P E+EA + K K + KE ++P + Sbjct: 448 EAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL 507 Query: 454 ----RIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTP 509 R P Y + ++ +++ ++ VI+YR+S+ A A M S S++ Sbjct: 508 TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA--MNSSPSVRS-----NI 560 Query: 510 QITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYS 569 ++T + T +N +VI++L+ Y I+ W+TK+E+P+T + +E L K FL +FVN Y+ Sbjct: 561 RVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYT 620 Query: 570 SCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIF-GNIKE 628 FYVAFFKG+FVG PG Y Y+F +R EEC PGGCL+EL QL+IIM GKQ+ N+ E Sbjct: 621 PIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFE 680 Query: 629 AIYPLALNWWRRRKARTNSE-------KLYSRWEQDHDLESFGPLGLFYEYLETVTQFGF 681 P R K + S K R+E D++LE F GL EY+E + QFGF Sbjct: 681 IGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGF 738 Query: 682 VTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSV 741 VTLFVASFPLAPL AL+NNI+EIR+DA K T+ RR VA +A IG+W +IL G+ L+V Sbjct: 739 VTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV 798 Query: 742 ATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF- 800 NAF+++FTSD IPRLVY Y YS N T M G+VN++LS F ++DF N TAP++ D Sbjct: 799 IINAFVISFTSDFIPRLVYLYMYSKNGT--MHGFVNHTLSSFNVSDFQNGTAPNDPLDLG 856 Query: 801 ---ITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVP 857 CRY+DYR PP ENKY + FW VLAA++ F+IV +++V + + W+IPD+P Sbjct: 857 YEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIP 916 Query: 858 KDVVERIKREKLMTIKILHDFELNK 882 KD+ ++I +EK++ +++ E +K Sbjct: 917 KDISQQIHKEKVLMVELFMREEQDK 941 >gi|209862785 anoctamin 2 [Homo sapiens] Length = 998 Score = 623 bits (1606), Expect = e-178 Identities = 345/828 (41%), Positives = 499/828 (60%), Gaps = 59/828 (7%) Query: 94 ELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIK 153 E + E+R+EFE NL + GLELE +D + G + FV+IHAPW+VL AE L IK+P K Sbjct: 149 EERKEQREEFEHNLMEAGLELE-KDLENKSQG-SIFVRIHAPWQVLAREAEFLKIKVPTK 206 Query: 154 ES-DIPRPKHTPISYVLGPVRLPLSVKYPHPEY-------FTAQFSRHRQELFLIEDQAT 205 + +I + +L ++ PE+ + FSR + L+ I+++ T Sbjct: 207 KMYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQEKDT 266 Query: 206 FFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNP 265 FF +++R+RIV+ IL R GI L+ +N Y +AYPLHDG+Y P + Sbjct: 267 FFDNATRSRIVHEILKRT--ACSRANNTMGINSLIANNIYEAAYPLHDGEY---DSPEDD 321 Query: 266 TNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFI 325 N+R L+Q WAR+ FYK QP+DLI+ Y+GEKIG+YF +LG YT L ++V+G+ F+ Sbjct: 322 MNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFL 381 Query: 326 YGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFF 385 YG ++E + S E+CD + MCPLCD+ CDYW L+S C ++ SHLFDN +TVFF Sbjct: 382 YGCATIEEDIPSREMCDQQ--NAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFF 439 Query: 386 AIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQ--LRPEFEA-----MCKHRKL 438 +IFM +W T+FLE WK+ Q RL Y WDL EEE+++ Q RPE+E M K Sbjct: 440 SIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQ 499 Query: 439 NAVTK-----------EMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVF 487 +AV K + E + R P Y ++ A++ ++L + + VIVYR++ Sbjct: 500 SAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRIT-- 557 Query: 488 ATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRT 547 T A+ + A+ V+ +T + T +N +VILIL+ Y ++ W+TK+E+P+T Sbjct: 558 -TAAALSLNKATRSNVR------VTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKT 610 Query: 548 YQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLI 607 Q +E L LK FL +FVN YS FYVAFFKG+FVG PG Y Y+F+ +R EEC PGGCL+ Sbjct: 611 EQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLM 670 Query: 608 ELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRKARTNS-------EKLYSRWEQDHD 659 EL QL+IIM GKQ+ NI E P +R+ K T + K +W+ D+ Sbjct: 671 ELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYS 730 Query: 660 LESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTV 719 LE + GL EY+E + QFGFVTLFVASFPLAP+ AL+NN++E+R+DA K T+ RR Sbjct: 731 LEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPD 788 Query: 720 ASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNS 779 A + IG+W DIL G+ SV +NAF++A TSD IPRLVY Y+YS N T + G+VN++ Sbjct: 789 AVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGT--LHGFVNHT 846 Query: 780 LSVFLIADFPNHTAPSEK---RDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFII 836 LS F ++ T P ++ CR++DYR PP N Y + Q+W +L+A++ F+I Sbjct: 847 LSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVI 906 Query: 837 VMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLK 884 + +++V + L+ WMIPD+P D+ ++IK+EK + + E KLK Sbjct: 907 IFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954 >gi|145207958 transmembrane protein 16G isoform NGEP long [Homo sapiens] Length = 933 Score = 543 bits (1398), Expect = e-154 Identities = 326/830 (39%), Positives = 482/830 (58%), Gaps = 64/830 (7%) Query: 77 RQIDFVLSYVDDVKKD----------AELKAERRKEFETNLRKTGLELEIEDKRDSEDGR 126 R DFVL + +D+K D ++ R+ F NLR GL + D++D +DG Sbjct: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCV---DQQDVQDGN 164 Query: 127 T--YFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLP--LSVKYPH 182 T ++ + A W VL YAE L +K+P++E +P + +L + +P L P Sbjct: 165 TTVHYALLSASWAVLCYYAEDLRLKLPLQE--LPNQASNWSAGLLAWLGIPNVLLEVVPD 222 Query: 183 --PEYFTAQFSRHRQELFLIED-QATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239 PEY++ +F ++ FL D Q TFF S+ R++I++ IL++ P+G E K GI +L Sbjct: 223 VPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEK-KNLLGIHQL 281 Query: 240 LNSNTYSSAYPLHDGQYWKPSEPPNPT--NERYTLHQNWARFSYFYKEQPLDLIKNYYGE 297 L S+A+PLHDG + P E P N+R L Q+WAR+ + K QPLD ++ Y+GE Sbjct: 282 LAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGE 341 Query: 298 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 357 K+ +YF +LGFYT L AAVVG F+ G + + + E+C + +M CPLC Sbjct: 342 KVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEM--CPLCLD 399 Query: 358 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 417 C +W L+S C ++ LFD+ TVFF++FM +W L LE+WK++ A L Y WD D+E Sbjct: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458 Query: 418 EEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMV 477 + +++ RP+F A N +T E EPY P +R + + +++VV +V Sbjct: 459 DTEERP--RPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLV 516 Query: 478 AVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISA 537 ++I+YR ++ A S + L S + SLTGS +N + ILIL+ Y ++ Sbjct: 517 SIILYR-AIMAIVVS-RSGNTLLAAWASRIA-----SLTGSVVNLVFILILSKIYVSLAH 569 Query: 538 WITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRS 597 +T+ E+ RT ++E + TLK+F+FQFVNFYSS Y+AFFKG+FVGYPG Y LF R+ Sbjct: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RN 628 Query: 598 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWW-------RRRKARTNSEKL 650 EEC GGCLIEL +L +IM GKQ+ N++E + P WW ++RKA ++ Sbjct: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688 Query: 651 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 710 WE D++L GLF EYLE V QFGFVT+FVA+ PLAPL AL+NN VEIR+DA K Sbjct: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746 Query: 711 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQ 770 +YRR VA +A IG+W IL G+ L+V +NAF++AF+SD +PR Y + Sbjct: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW----TRAH 802 Query: 771 PMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAA 830 + G++N F +A P+ A + R TCRYR +R DD+ Y + +W++LA Sbjct: 803 DLRGFLN-----FTLARAPSSFAAAHNR---TCRYRAFR---DDDGHY--SQTYWNLLAI 849 Query: 831 KMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 880 ++ F+IV EHVVF V LL ++PD+P+ V ++KRE + + L + E+ Sbjct: 850 RLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899 >gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] Length = 782 Score = 437 bits (1123), Expect = e-122 Identities = 238/649 (36%), Positives = 365/649 (56%), Gaps = 55/649 (8%) Query: 237 ERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYG 296 E L+ + + +PLH G+ L + WAR+ + ++EQP+D I+NY+G Sbjct: 139 EDLMKDGVFEARFPLHKGEG--------------RLKKTWARWRHMFREQPVDEIRNYFG 184 Query: 297 EKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCD 356 EK+ +YFV+LG+YT ML AA+ GL F+ G E + S EIC+ ++MCPL D Sbjct: 185 EKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAH---DILMCPLGD 241 Query: 357 QVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDF 416 Y RL+ TC +K +HLFDN+ TV FAIFM +W T+FLE WK+++AR+ WDL + Sbjct: 242 HSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVW 301 Query: 417 EEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSM 476 +EEQ+++ L+ +N ++ PY Y R +TV L ++L++ + Sbjct: 302 DEEQEEMALQ----------LINCPDYKLRPYQHSYLR--------STVILVLTLLMICL 343 Query: 477 VAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSL--TGSCLNFIVILILNFFYEK 534 + + + L V+ AS + S +++ FL Q+TT++ TG+ ++++ I+I+ Sbjct: 344 MIGMAHVLVVYRVLASALFSSSAVP----FLEEQVTTAVVVTGALVHYVTIIIMTKINRC 399 Query: 535 ISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNE 594 ++ + E+PRT+ E ES T++ F QF +SS Y+AF G+ G+PGK T L Sbjct: 400 VALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGL 459 Query: 595 WRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNS----EKL 650 W+ EEC GC+++L Q+ IIM KQ N E + P + R +A + + Sbjct: 460 WKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPE 519 Query: 651 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 710 W +++ L LF E++E + Q+GF T+FVA+FPLAPLLAL +N+VEIR+DA K Sbjct: 520 LRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIK 579 Query: 711 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYS----- 765 + RR V KA IG W +L + VL+V N ++AFTS+ IPR+VY Y YS Sbjct: 580 MVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKE 639 Query: 766 -TNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQF 824 + + GYVN+SLSVF DF + + CRYRDYR PPD Y + QF Sbjct: 640 GNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPD----YNFSEQF 695 Query: 825 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIK 873 W +LA ++ F+I+ EHV +K + AW +PD+P+ V ++ K ++ Sbjct: 696 WFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLR 744 >gi|94536803 transmembrane protein 16K [Homo sapiens] Length = 660 Score = 153 bits (386), Expect = 8e-37 Identities = 138/531 (25%), Positives = 218/531 (41%), Gaps = 120/531 (22%) Query: 236 IERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNW-ARFSYFYKEQPLDLIKNY 294 + RLL S +PLHD + K L W RF+ Y QP+D I+ Y Sbjct: 158 LRRLLTSGIVIQVFPLHDSEALKK------------LEDTWYTRFALKY--QPIDSIRGY 203 Query: 295 YGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPL 354 +GE I +YF FL ++T L AV+GL +++ Sbjct: 204 FGETIALYFGFLEYFTFALIPMAVIGLPYYLF---------------------------- 235 Query: 355 CDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLV 414 W D + V FA F IW T+ LE WK+ A + Y W + Sbjct: 236 ------VWE--------------DYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTL 275 Query: 415 DFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTR-IPWYFLSGATVTLWMSLVV 473 + + ++ RP F + +N++T + EP P Y R + Y +S V L L Sbjct: 276 LMKRKFEEP--RPGFHGVLG---INSITGKEEPLYPSYKRQLRIYLVSLPFVCL--CLYF 328 Query: 474 TSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYE 533 + V +I + + V+A E+ S P I + IVI I+N Y Sbjct: 329 SLYVMMIYFDMEVWAL--GLHENSGSEWTSVLLYVPSIIYA--------IVIEIMNRLYR 378 Query: 534 KISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFN 593 + ++T E R Y++ L LK+ +F F+N ++S FY+AF + Sbjct: 379 YAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAF--------------VLK 424 Query: 594 EWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSR 653 + + L L ++ QI I E+ P +W +RK ++ Sbjct: 425 DMKL-----------LRQSLATLLITSQILNQIMESFLP----YWLQRKHGVRVKRKVQA 469 Query: 654 WEQDHDLESFGP----------LGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVE 703 + D D + LG F +YLE QFG+V+LF +PLA A++NN E Sbjct: 470 LKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTE 529 Query: 704 IRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDI 754 + DA K+ ++R + + +IGVWQ M+V+SV TN ++ + + Sbjct: 530 VNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQV 580 Score = 38.9 bits (89), Expect = 0.022 Identities = 18/67 (26%), Positives = 37/67 (55%) Query: 821 NMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 880 N F A + ++ +EH + +KF+LA+ IPD P+ + ++ R + +++ L ++ Sbjct: 581 NAVFPESKADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQM 640 Query: 881 NKLKENL 887 + ENL Sbjct: 641 KLVTENL 647 >gi|55741655 anoctamin 8 [Homo sapiens] Length = 1232 Score = 110 bits (276), Expect = 5e-24 Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 85/385 (22%) Query: 200 IEDQATFFPSSSRNRIVYYILS--RCPFGIEDGKKRFG-----IERLLNSNTYSSAYPLH 252 +E + FF S R I+ + L R G RF I L +P+H Sbjct: 153 VESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVH 212 Query: 253 DGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEM 312 + + L ++W + + QPLD I +Y+G KI +YF +LGFYT Sbjct: 213 EQRILN------------RLMKSWVQA--VCENQPLDDICDYFGVKIAMYFAWLGFYTSA 258 Query: 313 LFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASK 372 + + AV G + + E + +S ++ Sbjct: 259 MVYPAVFGSVLYTF----TEADQTSRDV-------------------------------- 282 Query: 373 FSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAM 432 S V FA+F IW TLFLE WK+R A L Y+W +D E + + RP+F + Sbjct: 283 --------SCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVE-EPRPQFRGV 333 Query: 433 CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFAS 492 R+++ +T+ E Y P + R+ + L + L + +V V + L F Sbjct: 334 ---RRISPITRAEEFYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQ-LQE 383 Query: 493 FMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 552 + S L ++ FL P++ +L ++ + Y+K++ W+ ME R YE Sbjct: 384 LVLSVKGLPRLARFL-PKVMLAL--------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434 Query: 553 SSLTLKMFLFQFVNFYSSCFYVAFF 577 L +K+ LFQFVN Y S FY+ F+ Sbjct: 435 KHLIIKVVLFQFVNSYLSLFYIGFY 459 Score = 82.0 bits (201), Expect = 2e-15 Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 9/118 (7%) Query: 640 RRKARTNSEKLYSRWEQDH-------DLESFGPL--GLFYEYLETVTQFGFVTLFVASFP 690 RR+ R N E++H +LES F +Y E QFG+V LF ++FP Sbjct: 707 RRQRRQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFP 766 Query: 691 LAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIV 748 LA L AL+NN++EIR DA+KL T +R + SIG WQ ++ M VL++ N +++ Sbjct: 767 LAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824 Score = 32.7 bits (73), Expect = 1.6 Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 825 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKR 866 W A + ++V+EH L+K+L+ IPD+P V E + + Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAK 877 >gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] Length = 494 Score = 67.0 bits (162), Expect = 8e-11 Identities = 44/130 (33%), Positives = 64/130 (49%), Gaps = 31/130 (23%) Query: 598 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQD 657 ++C PGGC I++T QL IIM GKQ+ +++E + Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV--------------------------- 263 Query: 658 HDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRR 717 G G L + QFGF+T+FV +F LAPL L+NN VEI +DA K +Y+R Sbjct: 264 ---GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQR 319 Query: 718 TVASKAHSIG 727 +A + + G Sbjct: 320 PMAGRGWTSG 329 Score = 50.8 bits (120), Expect = 6e-06 Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 34/163 (20%) Query: 372 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 420 K S LFD+ TVFF+IFM W + A L + WD DF++++ Sbjct: 50 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 109 Query: 421 ----QQLQLRP---------------EFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLS 461 Q ++ P EF A+ N VT EPY ++ + S Sbjct: 110 CSDFQDQEVMPSSALHHWDCSDFQDQEFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTS 169 Query: 462 GATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500 A + + +V+ +V+VI+Y +++F T S + + A++ Sbjct: 170 SAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 212 >gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] Length = 723 Score = 66.2 bits (160), Expect = 1e-10 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%) Query: 599 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 658 +C PGGC I++T QL IIM GKQ+ +++E + Sbjct: 461 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 492 Query: 659 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 718 G G L + QFGF+T+FV +F LAPL L+NN VEI +DA K +Y+R Sbjct: 493 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 549 Query: 719 VASKAHSIG 727 +A + + G Sbjct: 550 MAGRGWTSG 558 Score = 40.4 bits (93), Expect = 0.008 Identities = 37/165 (22%), Positives = 65/165 (39%), Gaps = 40/165 (24%) Query: 376 LFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ--------------- 420 L D TVFF+IFM W + A L + WD DF++++ Sbjct: 262 LGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDF 321 Query: 421 QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYF 459 Q ++ P +F A+ N VT EPY ++ + Sbjct: 322 QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLL 381 Query: 460 LSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500 S A + + +V+ +V+VI+Y +++F T S + + A++ Sbjct: 382 TSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 426 >gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] Length = 719 Score = 66.2 bits (160), Expect = 1e-10 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 31/129 (24%) Query: 599 ECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDH 658 +C PGGC I++T QL IIM GKQ+ +++E + Sbjct: 457 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV---------------------------- 488 Query: 659 DLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRT 718 G G L + QFGF+T+FV +F LAPL L+NN VEI +DA K +Y+R Sbjct: 489 --GLGGGPGPDTPCLPEL-QFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 545 Query: 719 VASKAHSIG 727 +A + + G Sbjct: 546 MAGRGWTSG 554 Score = 47.4 bits (111), Expect = 6e-05 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 40/169 (23%) Query: 372 KFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ----------- 420 K S LFD+ TVFF+IFM W + A L + WD DF++++ Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313 Query: 421 ----QQLQLRP---------------------EFEAMCKHRKLNAVTKEMEPYMPLYTRI 455 Q ++ P +F A+ N VT EPY ++ + Sbjct: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCL 373 Query: 456 PWYFLSGATVTLWMSLVVTSMVAVIVYR----LSVFATFASFMESDASL 500 S A + + +V+ +V+VI+Y +++F T S + + A++ Sbjct: 374 SHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANV 422 >gi|22748943 hypothetical protein LOC145483 [Homo sapiens] Length = 647 Score = 37.0 bits (84), Expect = 0.084 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query: 403 RQARLEYEW--DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRI 455 R+AR + EW FE+E+Q+ Q + E EA C HR+ A Y+PLY I Sbjct: 180 REARKKAEWLGSPASFEQERQRAQRQGEEEAEC-HRQFRAQPVPAHVYLPLYQEI 233 >gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] Length = 2459 Score = 33.5 bits (75), Expect = 0.93 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 15/135 (11%) Query: 445 MEPYMPLYT---RIPWYFLSGATVTLWMSLVVTSMVAVIVY--RLSVFATFASFMESDAS 499 + P M + T R W +SG + + L+ S+ + +++ +L + T E+ S Sbjct: 2293 LNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVS 2352 Query: 500 LK-------QVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 552 L+ +V + +P + + L GSC+ F+ ++LN F I + E + YQ E Sbjct: 2353 LQLGIFNYEEVLDY-SPVLGSFLIGSCIVFMTFVVLNLFISVI--LVAFSEEQKYYQLSE 2409 Query: 553 SSLTLKMFLFQFVNF 567 + + L + ++F Sbjct: 2410 EGEIVDLLLMKILSF 2424 >gi|51477723 testis expressed sequence 11 isoform 2 [Homo sapiens] Length = 925 Score = 32.0 bits (71), Expect = 2.7 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 451 LYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLT-- 508 LY ++ A +T+ V + V+ Y+ F + + Q K L Sbjct: 140 LYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRL 199 Query: 509 PQITTSLTGSCLNFIVILILNFFYEKISAWITK 541 PQ+T+SL C NF V N YE+ S W+++ Sbjct: 200 PQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQ 232 >gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens] Length = 940 Score = 32.0 bits (71), Expect = 2.7 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 451 LYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLT-- 508 LY ++ A +T+ V + V+ Y+ F + + Q K L Sbjct: 155 LYVKLIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRL 214 Query: 509 PQITTSLTGSCLNFIVILILNFFYEKISAWITK 541 PQ+T+SL C NF V N YE+ S W+++ Sbjct: 215 PQMTSSLHHLCYNFGVETQKNNKYEESSFWLSQ 247 >gi|5454014 tripartite motif-containing 38 [Homo sapiens] Length = 465 Score = 31.2 bits (69), Expect = 4.6 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 5/49 (10%) Query: 858 KDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMIEENKAQ 906 K + R+++E+ T+ L D+E LG+ SNE H++ E K Q Sbjct: 195 KSYLWRLEKEEQQTLSRLRDYEAG-----LGLKSNELKSHILELEEKCQ 238 >gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens] Length = 300 Score = 31.2 bits (69), Expect = 4.6 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 593 NEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLA 634 N W ++ C G C+++L+ L I GK +F K+A +P + Sbjct: 111 NTWSAQNCKNGSCVLDLSKCLFI--QGKLLFAEPKDAGFPFS 150 >gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens] Length = 300 Score = 31.2 bits (69), Expect = 4.6 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 593 NEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLA 634 N W ++ C G C+++L+ L I GK +F K+A +P + Sbjct: 111 NTWSAQNCKNGSCVLDLSKCLFI--QGKLLFAEPKDAGFPFS 150 >gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] Length = 4588 Score = 30.8 bits (68), Expect = 6.0 Identities = 28/148 (18%), Positives = 64/148 (43%), Gaps = 21/148 (14%) Query: 82 VLSYVDDVKKDAELKAERRKEFETNLRKTGLE---LEIEDKRDSEDGRTYFVKIHAPWEV 138 V ++ +D ++D E++ R + K G E +E D+ D E Y++ + A + Sbjct: 1056 VSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQG 1115 Query: 139 LVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKYPHPEYFTAQFSRHRQELF 198 +V + + I + +++ + P+ + P Y+ +++ Sbjct: 1116 VVPLSSFIEIYIEVEDVNDNAPQTS------------------EPVYYPEIMENSPKDVS 1157 Query: 199 LIEDQATFFPSSSRNRIVYYILSRCPFG 226 +++ +A SSS ++++Y I S P G Sbjct: 1158 VVQIEAFDPDSSSNDKLMYKITSGNPQG 1185 >gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo sapiens] Length = 1719 Score = 30.8 bits (68), Expect = 6.0 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Query: 7 LEVLAEEGEKVNKHIDYSFQMSESLS--SRETSFLINEETMPAKRFNLFLRRRLMFQKNQ 64 ++ L +E E +NK + Q SE L S+E + + + F + + RL Q Sbjct: 537 IKTLQQEREDLNKEL---VQASERLKNQSKELKDAHCQRKLAMQEF-MEINERLTELHTQ 592 Query: 65 QSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSED 124 + K + RD ++D V+ V+ ++++ +KE E + E +D++ E Sbjct: 593 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEAS-KDRKLREQ 651 Query: 125 GRTY 128 Y Sbjct: 652 SEHY 655 >gi|44955929 calmodulin regulated spectrin-associated protein 1-like 1 [Homo sapiens] Length = 1478 Score = 30.8 bits (68), Expect = 6.0 Identities = 16/39 (41%), Positives = 24/39 (61%) Query: 89 VKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRT 127 +K+ A L+ R+E ET LRK LE E+E K++ +T Sbjct: 1166 MKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKT 1204 >gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo sapiens] Length = 402 Score = 30.4 bits (67), Expect = 7.8 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%) Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712 RWE ++ G L F+ T+T FG +LF+AS + + IR W Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165 Query: 713 TQYRRTVASKAHSIGVWQDIL 733 + +T A++A +GVW +L Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186 >gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo sapiens] Length = 388 Score = 30.4 bits (67), Expect = 7.8 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%) Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712 RWE ++ G L F+ T+T FG +LF+AS + + IR W Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165 Query: 713 TQYRRTVASKAHSIGVWQDIL 733 + +T A++A +GVW +L Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186 >gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo sapiens] Length = 390 Score = 30.4 bits (67), Expect = 7.8 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 13/81 (16%) Query: 653 RWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLT 712 RWE ++ G L F+ T+T FG +LF+AS + + IR W Sbjct: 119 RWEH---IDPSGRLCTFFGL--TMTVFGLSSLFIAS------AMAVERALAIRAPHW--Y 165 Query: 713 TQYRRTVASKAHSIGVWQDIL 733 + +T A++A +GVW +L Sbjct: 166 ASHMKTRATRAVLLGVWLAVL 186 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.138 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,072,605 Number of Sequences: 37866 Number of extensions: 1458583 Number of successful extensions: 4819 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 4667 Number of HSP's gapped (non-prelim): 72 length of query: 912 length of database: 18,247,518 effective HSP length: 111 effective length of query: 801 effective length of database: 14,044,392 effective search space: 11249557992 effective search space used: 11249557992 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.