Guide to the Human Genome
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Search of human proteins with 21729895

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21729895 mitogen-activated protein kinase kinase 5 isoform A
[Homo sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21729895 mitogen-activated protein kinase kinase 5 isoform A ...   904   0.0  
gi|4506101 mitogen-activated protein kinase kinase 5 isoform B [...   875   0.0  
gi|5579478 mitogen-activated protein kinase kinase 1 [Homo sapiens]   263   3e-70
gi|13489054 mitogen-activated protein kinase kinase 2 [Homo sapi...   254   1e-67
gi|14589900 mitogen-activated protein kinase kinase 6 [Homo sapi...   220   2e-57
gi|21618347 mitogen-activated protein kinase kinase 3 isoform A ...   209   3e-54
gi|21618349 mitogen-activated protein kinase kinase 3 isoform B ...   209   3e-54
gi|4506889 mitogen-activated protein kinase kinase 4 [Homo sapiens]   205   6e-53
gi|21735544 mitogen-activated protein kinase kinase 7 [Homo sapi...   169   4e-42
gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo...   167   2e-41
gi|21361358 serine/threonine kinase 25 [Homo sapiens]                 167   2e-41
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]      166   5e-41
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]       166   5e-41
gi|103471999 serine/threonine kinase 3 [Homo sapiens]                 165   7e-41
gi|5454096 serine/threonine kinase 4 [Homo sapiens]                   164   1e-40
gi|239757989 PREDICTED: similar to MAP kinase 3c [Homo sapiens]       150   2e-36
gi|15451902 mitogen-activated protein kinase kinase kinase kinas...   142   5e-34
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...   141   1e-33
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...   141   1e-33
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...   141   1e-33
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...   141   1e-33
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...   141   1e-33
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...   141   1e-33
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...   141   1e-33
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...   141   1e-33
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                141   1e-33
gi|22035600 mitogen-activated protein kinase kinase kinase kinas...   135   6e-32
gi|4826878 oxidative-stress responsive 1 [Homo sapiens]               134   2e-31
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]     134   2e-31
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]     134   2e-31

>gi|21729895 mitogen-activated protein kinase kinase 5 isoform A
           [Homo sapiens]
          Length = 448

 Score =  904 bits (2336), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF 60
           MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
Sbjct: 1   MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF 60

Query: 61  EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL 120
           EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
Sbjct: 61  EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL 120

Query: 121 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV 180
           KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
Sbjct: 121 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV 180

Query: 181 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC 240
           YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
Sbjct: 181 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC 240

Query: 241 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC 300
           TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
Sbjct: 241 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC 300

Query: 301 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ 360
           DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
Sbjct: 301 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ 360

Query: 361 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
           KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
Sbjct: 361 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420

Query: 421 QFNDGNAAVVSMWVCRALEERRSQQGPP 448
           QFNDGNAAVVSMWVCRALEERRSQQGPP
Sbjct: 421 QFNDGNAAVVSMWVCRALEERRSQQGPP 448


>gi|4506101 mitogen-activated protein kinase kinase 5 isoform B
           [Homo sapiens]
          Length = 438

 Score =  875 bits (2260), Expect = 0.0
 Identities = 438/448 (97%), Positives = 438/448 (97%), Gaps = 10/448 (2%)

Query: 1   MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF 60
           MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
Sbjct: 1   MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF 60

Query: 61  EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL 120
           EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
Sbjct: 61  EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL 120

Query: 121 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV 180
           KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
Sbjct: 121 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV 180

Query: 181 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC 240
           YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
Sbjct: 181 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC 240

Query: 241 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC 300
           TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
Sbjct: 241 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC 300

Query: 301 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ 360
           DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFME          IQ
Sbjct: 301 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFME----------IQ 350

Query: 361 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
           KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
Sbjct: 351 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 410

Query: 421 QFNDGNAAVVSMWVCRALEERRSQQGPP 448
           QFNDGNAAVVSMWVCRALEERRSQQGPP
Sbjct: 411 QFNDGNAAVVSMWVCRALEERRSQQGPP 438


>gi|5579478 mitogen-activated protein kinase kinase 1 [Homo sapiens]
          Length = 393

 Score =  263 bits (671), Expect = 3e-70
 Identities = 142/339 (41%), Positives = 204/339 (60%), Gaps = 41/339 (12%)

Query: 140 LPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILL 199
           L     K+  A L +    G++ + D      LG GNGG V+K  H PSG ++A K+I L
Sbjct: 42  LDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHL 101

Query: 200 DITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK----M 255
           +I   ++ QI+ EL++L++C+S YI+GFYGAF+ +  ISIC E MDGGSLD   K    +
Sbjct: 102 EIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRI 161

Query: 256 PEHVLGRIAVAVVKGLTYLWSL-KILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK 314
           PE +LG++++AV+KGLTYL    KI+HRDVKPSN+LVN+RG++KLCDFGVS QL++S+A 
Sbjct: 162 PEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN 221

Query: 315 TYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLM------- 367
           ++VGT +YM+PER+ G  Y + SD+WS+G+S +E+A+GR+P P     +  LM       
Sbjct: 222 SFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEG 281

Query: 368 --------------PL--------------QLLQCIVDEDSPVLPVGEFSEPFVHFITQC 399
                         PL              +LL  IV+E  P LP G FS  F  F+ +C
Sbjct: 282 DAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKC 341

Query: 400 MRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRAL 438
           + K P ER   ++LM H FI + +D      + W+C  +
Sbjct: 342 LIKNPAERADLKQLMVHAFIKR-SDAEEVDFAGWLCSTI 379


>gi|13489054 mitogen-activated protein kinase kinase 2 [Homo
           sapiens]
          Length = 400

 Score =  254 bits (649), Expect = 1e-67
 Identities = 142/353 (40%), Positives = 208/353 (58%), Gaps = 47/353 (13%)

Query: 140 LPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILL 199
           L     K+  A L +    G++ + D      LG GNGG V K  H PSG I+A K+I L
Sbjct: 46  LDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHL 105

Query: 200 DITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVY----RKM 255
           +I   ++ QI+ EL++L++C+S YI+GFYGAF+ +  ISIC E MDGGSLD      +++
Sbjct: 106 EIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRI 165

Query: 256 PEHVLGRIAVAVVKGLTYLWSL-KILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK 314
           PE +LG++++AV++GL YL    +I+HRDVKPSN+LVN+RG++KLCDFGVS QL++S+A 
Sbjct: 166 PEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMAN 225

Query: 315 TYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQ--------------IQ 360
           ++VGT +YMAPER+ G  Y + SD+WS+G+S +ELA+GR+P P               + 
Sbjct: 226 SFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVD 285

Query: 361 KNQG---SLMP----------------------LQLLQCIVDEDSPVLPVGEFSEPFVHF 395
             +G   S+ P                       +LL  IV+E  P LP G F+  F  F
Sbjct: 286 GEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEF 345

Query: 396 ITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP 448
           + +C+ K P ER   + L  H FI + ++      + W+C+ L  R +Q G P
Sbjct: 346 VNKCLIKNPAERADLKMLTNHTFIKR-SEVEEVDFAGWLCKTL--RLNQPGTP 395


>gi|14589900 mitogen-activated protein kinase kinase 6 [Homo
           sapiens]
          Length = 334

 Score =  220 bits (560), Expect = 2e-57
 Identities = 139/334 (41%), Positives = 192/334 (57%), Gaps = 28/334 (8%)

Query: 113 GERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTL 172
           G++   GLK+   A       P  S + P +   K+   +     N ++   D+     L
Sbjct: 6   GKKRNPGLKIPKEA----FEQPQTSSTPPRDLDSKACISIGN--QNFEVKADDLEPIMEL 59

Query: 173 GHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKC-DSSYIIGFYGAF 231
           G G  G V K  HVPSG+I+AVK I   +  + QK+++ +L+I  +  D  + + FYGA 
Sbjct: 60  GRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGAL 119

Query: 232 FVENRISICTEFMDGGSLDVYRK--------MPEHVLGRIAVAVVKGLTYLWS-LKILHR 282
           F E  + IC E MD  SLD + K        +PE +LG+IAV++VK L +L S L ++HR
Sbjct: 120 FREGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHR 178

Query: 283 DVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPERISGE----QYGIHS 337
           DVKPSN+L+N  GQVK+CDFG+S  LV+S+AKT   G   YMAPERI+ E     Y + S
Sbjct: 179 DVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKS 238

Query: 338 DVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFIT 397
           D+WSLGI+ +ELA+ RFPY     + G+  P Q L+ +V+E SP LP  +FS  FV F +
Sbjct: 239 DIWSLGITMIELAILRFPY----DSWGT--PFQQLKQVVEEPSPQLPADKFSAEFVDFTS 292

Query: 398 QCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS 431
           QC++K  KERP   ELM HPF          V S
Sbjct: 293 QCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS 326


>gi|21618347 mitogen-activated protein kinase kinase 3 isoform A
           [Homo sapiens]
          Length = 318

 Score =  209 bits (533), Expect = 3e-54
 Identities = 124/275 (45%), Positives = 166/275 (60%), Gaps = 20/275 (7%)

Query: 158 NGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEI-L 216
           N ++   D+     LG G  G V K  H  SG I+AVK I   +  + QK+++ +L+I +
Sbjct: 27  NFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINM 86

Query: 217 YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKM-------PEHVLGRIAVAVVK 269
              D  Y + FYGA F E  + IC E MD      YRK+       PE +LG IAV++V+
Sbjct: 87  RTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVR 146

Query: 270 GLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPER 327
            L +L S L ++HRDVKPSN+L+N  G VK+CDFG+S  LV+S+AKT   G   YMAPER
Sbjct: 147 ALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPER 206

Query: 328 ISGE----QYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVL 383
           I+ E     Y + SDVWSLGI+ +E+A+ RFPY    ++ G+  P Q L+ +V+E SP L
Sbjct: 207 INPELNQKGYNVKSDVWSLGITMIEMAILRFPY----ESWGT--PFQQLKQVVEEPSPQL 260

Query: 384 PVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPF 418
           P   FS  FV F  QC+RK P ER +  ELM HPF
Sbjct: 261 PADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPF 295


>gi|21618349 mitogen-activated protein kinase kinase 3 isoform B
           [Homo sapiens]
          Length = 347

 Score =  209 bits (533), Expect = 3e-54
 Identities = 124/275 (45%), Positives = 166/275 (60%), Gaps = 20/275 (7%)

Query: 158 NGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEI-L 216
           N ++   D+     LG G  G V K  H  SG I+AVK I   +  + QK+++ +L+I +
Sbjct: 56  NFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINM 115

Query: 217 YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKM-------PEHVLGRIAVAVVK 269
              D  Y + FYGA F E  + IC E MD      YRK+       PE +LG IAV++V+
Sbjct: 116 RTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVR 175

Query: 270 GLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPER 327
            L +L S L ++HRDVKPSN+L+N  G VK+CDFG+S  LV+S+AKT   G   YMAPER
Sbjct: 176 ALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPER 235

Query: 328 ISGE----QYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVL 383
           I+ E     Y + SDVWSLGI+ +E+A+ RFPY    ++ G+  P Q L+ +V+E SP L
Sbjct: 236 INPELNQKGYNVKSDVWSLGITMIEMAILRFPY----ESWGT--PFQQLKQVVEEPSPQL 289

Query: 384 PVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPF 418
           P   FS  FV F  QC+RK P ER +  ELM HPF
Sbjct: 290 PADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPF 324


>gi|4506889 mitogen-activated protein kinase kinase 4 [Homo sapiens]
          Length = 399

 Score =  205 bits (522), Expect = 6e-53
 Identities = 125/304 (41%), Positives = 178/304 (58%), Gaps = 27/304 (8%)

Query: 164 QDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKC-DSS 222
           +D++    +G G  G+V K  H PSG+I+AVK I   +  + QKQ++ +L+++ +  D  
Sbjct: 100 EDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCP 159

Query: 223 YIIGFYGAFFVENRISICTEFMDGGSLDVYRK---------MPEHVLGRIAVAVVKGLTY 273
           YI+ FYGA F E    IC E M   S D + K         +PE +LG+I +A VK L +
Sbjct: 160 YIVQFYGALFREGDCWICMELMST-SFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH 218

Query: 274 LW-SLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPERI--- 328
           L  +LKI+HRD+KPSN+L++  G +KLCDFG+S QLV+SIAKT   G   YMAPERI   
Sbjct: 219 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS 278

Query: 329 -SGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVG- 386
            S + Y + SDVWSLGI+  ELA GRFPYP+             L  +V  D P L    
Sbjct: 279 ASRQGYDVRSDVWSLGITLYELATGRFPYPKWNS------VFDQLTQVVKGDPPQLSNSE 332

Query: 387 --EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQ 444
             EFS  F++F+  C+ K   +RP  +EL+ HPFI+ + +  A  V+ +VC+ L++  + 
Sbjct: 333 EREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEE-RAVEVACYVCKILDQMPAT 391

Query: 445 QGPP 448
              P
Sbjct: 392 PSSP 395


>gi|21735544 mitogen-activated protein kinase kinase 7 [Homo
           sapiens]
          Length = 419

 Score =  169 bits (429), Expect = 4e-42
 Identities = 114/322 (35%), Positives = 176/322 (54%), Gaps = 25/322 (7%)

Query: 128 PSQHSSPAVSDSLP-SNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGT---VYKA 183
           PS   +P   +S+     L++   +   +   GQ  + +I   + LG    GT   V+K 
Sbjct: 78  PSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKM 137

Query: 184 YHVPSGKILAVKVILLDITLELQKQIMSELEILYKC-DSSYIIGFYGAFFVENRISICTE 242
               +G ++AVK +      E  K+I+ +L+++ K  D  YI+  +G F     + I  E
Sbjct: 138 RFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAME 197

Query: 243 FMDGGSLDVYRKM----PEHVLGRIAVAVVKGLTYLWSLK-ILHRDVKPSNMLVNTRGQV 297
            M   +  + ++M    PE +LG++ VA+VK L YL     ++HRDVKPSN+L++ RGQ+
Sbjct: 198 LMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQI 257

Query: 298 KLCDFGVSTQLVNSIAKT-YVGTNAYMAPERI-----SGEQYGIHSDVWSLGISFMELAL 351
           KLCDFG+S +LV+S AKT   G  AYMAPERI     +   Y I +DVWSLGIS +ELA 
Sbjct: 258 KLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELAT 317

Query: 352 GRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLP--VGEFSEPFVHFITQCMRKQPKERPA 409
           G+FPY   + +       ++L  ++ E+ P+LP  +G FS  F  F+  C+ K  ++RP 
Sbjct: 318 GQFPYKNCKTD------FEVLTKVLQEEPPLLPGHMG-FSGDFQSFVKDCLTKDHRKRPK 370

Query: 410 PEELMGHPFIVQFNDGNAAVVS 431
             +L+ H FI ++      V S
Sbjct: 371 YNKLLEHSFIKRYETLEVDVAS 392


>gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo
           sapiens]
          Length = 416

 Score =  167 bits (422), Expect = 2e-41
 Identities = 96/257 (37%), Positives = 154/257 (59%), Gaps = 13/257 (5%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYG 229
           + +G G+ G V+K     + +++A+K+I L+   +  + I  E+ +L +CDSSY+  +YG
Sbjct: 28  ERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYG 87

Query: 230 AFFVENRISICTEFMDGGS-LDVYRKMP--EHVLGRIAVAVVKGLTYLWSLKILHRDVKP 286
           ++   +++ I  E++ GGS LD+ R  P  E  +  +   ++KGL YL S K +HRD+K 
Sbjct: 88  SYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKA 147

Query: 287 SNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHSDVWSLGI 344
           +N+L++ +G VKL DFGV+ QL ++  K  T+VGT  +MAPE I    Y   +D+WSLGI
Sbjct: 148 ANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGI 207

Query: 345 SFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQP 404
           + +ELA G  P          + P+++L  I   + P L VG+F++ F  FI  C+ K P
Sbjct: 208 TAIELAKGEPP-------NSDMHPMRVLFLIPKNNPPTL-VGDFTKSFKEFIDACLNKDP 259

Query: 405 KERPAPEELMGHPFIVQ 421
             RP  +EL+ H FIV+
Sbjct: 260 SFRPTAKELLKHKFIVK 276


>gi|21361358 serine/threonine kinase 25 [Homo sapiens]
          Length = 426

 Score =  167 bits (422), Expect = 2e-41
 Identities = 94/258 (36%), Positives = 154/258 (59%), Gaps = 13/258 (5%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYG 229
           D +G G+ G VYK     + +++A+K+I L+   +  + I  E+ +L +CDS YI  ++G
Sbjct: 24  DRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFG 83

Query: 230 AFFVENRISICTEFMDGGS-LDVYRKMP--EHVLGRIAVAVVKGLTYLWSLKILHRDVKP 286
           ++    ++ I  E++ GGS LD+ +  P  E  +  I   ++KGL YL S + +HRD+K 
Sbjct: 84  SYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKA 143

Query: 287 SNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHSDVWSLGI 344
           +N+L++ +G VKL DFGV+ QL ++  K  T+VGT  +MAPE I    Y   +D+WSLGI
Sbjct: 144 ANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGI 203

Query: 345 SFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQP 404
           + +ELA G  P          L P+++L  ++ ++SP    G+ S+PF  F+  C+ K P
Sbjct: 204 TAIELAKGEPP-------NSDLHPMRVL-FLIPKNSPPTLEGQHSKPFKEFVEACLNKDP 255

Query: 405 KERPAPEELMGHPFIVQF 422
           + RP  +EL+ H FI ++
Sbjct: 256 RFRPTAKELLKHKFITRY 273


>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
          Length = 431

 Score =  166 bits (419), Expect = 5e-41
 Identities = 94/257 (36%), Positives = 153/257 (59%), Gaps = 13/257 (5%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYG 229
           + +G G+ G V+K     + K++A+K+I L+   +  + I  E+ +L +CDS Y+  +YG
Sbjct: 28  EKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG 87

Query: 230 AFFVENRISICTEFMDGGS-LDVYRKMP--EHVLGRIAVAVVKGLTYLWSLKILHRDVKP 286
           ++  + ++ I  E++ GGS LD+    P  E  +  I   ++KGL YL S K +HRD+K 
Sbjct: 88  SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKA 147

Query: 287 SNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHSDVWSLGI 344
           +N+L++  G+VKL DFGV+ QL ++  K  T+VGT  +MAPE I    Y   +D+WSLGI
Sbjct: 148 ANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGI 207

Query: 345 SFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQP 404
           + +ELA G  P+ +       L P+++L  I   + P L  G +S+P   F+  C+ K+P
Sbjct: 208 TAIELARGEPPHSE-------LHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEP 259

Query: 405 KERPAPEELMGHPFIVQ 421
             RP  +EL+ H FI++
Sbjct: 260 SFRPTAKELLKHKFILR 276


>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
          Length = 443

 Score =  166 bits (419), Expect = 5e-41
 Identities = 94/257 (36%), Positives = 153/257 (59%), Gaps = 13/257 (5%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYG 229
           + +G G+ G V+K     + K++A+K+I L+   +  + I  E+ +L +CDS Y+  +YG
Sbjct: 40  EKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYG 99

Query: 230 AFFVENRISICTEFMDGGS-LDVYRKMP--EHVLGRIAVAVVKGLTYLWSLKILHRDVKP 286
           ++  + ++ I  E++ GGS LD+    P  E  +  I   ++KGL YL S K +HRD+K 
Sbjct: 100 SYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKA 159

Query: 287 SNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHSDVWSLGI 344
           +N+L++  G+VKL DFGV+ QL ++  K  T+VGT  +MAPE I    Y   +D+WSLGI
Sbjct: 160 ANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGI 219

Query: 345 SFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQP 404
           + +ELA G  P+ +       L P+++L  I   + P L  G +S+P   F+  C+ K+P
Sbjct: 220 TAIELARGEPPHSE-------LHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEP 271

Query: 405 KERPAPEELMGHPFIVQ 421
             RP  +EL+ H FI++
Sbjct: 272 SFRPTAKELLKHKFILR 288


>gi|103471999 serine/threonine kinase 3 [Homo sapiens]
          Length = 491

 Score =  165 bits (418), Expect = 7e-41
 Identities = 98/287 (34%), Positives = 163/287 (56%), Gaps = 23/287 (8%)

Query: 141 PSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLD 200
           P + LKK S +     +  +  E+     + LG G+ G+V+KA H  SG+++A+K + ++
Sbjct: 7   PKSKLKKLSED-----SLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE 61

Query: 201 ITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSL-DVYR----KM 255
             L+   +I+ E+ I+ +CDS Y++ +YG++F    + I  E+   GS+ D+ R     +
Sbjct: 62  SDLQ---EIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTL 118

Query: 256 PEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK- 314
            E  +  I  + +KGL YL  ++ +HRD+K  N+L+NT G  KL DFGV+ QL +++AK 
Sbjct: 119 IEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR 178

Query: 315 -TYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQ 373
            T +GT  +MAPE I    Y   +D+WSLGI+ +E+A G+ PY  I        P++ + 
Sbjct: 179 NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIH-------PMRAIF 231

Query: 374 CIVDEDSPVLPVGE-FSEPFVHFITQCMRKQPKERPAPEELMGHPFI 419
            I     P     E +S+ F  F+ +C+ K P++R    +L+ HPFI
Sbjct: 232 MIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 278


>gi|5454096 serine/threonine kinase 4 [Homo sapiens]
          Length = 487

 Score =  164 bits (416), Expect = 1e-40
 Identities = 92/258 (35%), Positives = 152/258 (58%), Gaps = 18/258 (6%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYG 229
           + LG G+ G+VYKA H  +G+I+A+K + ++  L+   +I+ E+ I+ +CDS +++ +YG
Sbjct: 34  EKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVKYYG 90

Query: 230 AFFVENRISICTEFMDGGSL-DVYR----KMPEHVLGRIAVAVVKGLTYLWSLKILHRDV 284
           ++F    + I  E+   GS+ D+ R     + E  +  I  + +KGL YL  ++ +HRD+
Sbjct: 91  SYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDI 150

Query: 285 KPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHSDVWSL 342
           K  N+L+NT G  KL DFGV+ QL +++AK  T +GT  +MAPE I    Y   +D+WSL
Sbjct: 151 KAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSL 210

Query: 343 GISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGE-FSEPFVHFITQCMR 401
           GI+ +E+A G+ PY  I        P++ +  I     P     E +S+ F  F+ QC+ 
Sbjct: 211 GITAIEMAEGKPPYADIH-------PMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLV 263

Query: 402 KQPKERPAPEELMGHPFI 419
           K P++R    +L+ HPF+
Sbjct: 264 KSPEQRATATQLLQHPFV 281


>gi|239757989 PREDICTED: similar to MAP kinase 3c [Homo sapiens]
          Length = 353

 Score =  150 bits (379), Expect = 2e-36
 Identities = 89/202 (44%), Positives = 120/202 (59%), Gaps = 14/202 (6%)

Query: 158 NGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEI-L 216
           N ++   D+     LG G  G V K  H  SG I+AVK+I   +    QK+++ +L+I +
Sbjct: 61  NFEVEADDLVTIPELGRGAYGVVEKVRHTQSGTIMAVKLIWATVNSXEQKRLLMDLDINM 120

Query: 217 YKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKM-------PEHVLGRIAVAVVK 269
              D  Y + FYGA F E  + IC E MD      YRK+       PE +LG IAV++V+
Sbjct: 121 RTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVR 180

Query: 270 GLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTY-VGTNAYMAPER 327
            L +L S L ++HRDVKPSN+L+N  G VK+CDFG+S  LV+S+AK    G   YMAPER
Sbjct: 181 ALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKMMDAGCKPYMAPER 240

Query: 328 ISGE----QYGIHSDVWSLGIS 345
           I+ E     Y + SDVWSLGI+
Sbjct: 241 INPELNQKGYNVKSDVWSLGIT 262


>gi|15451902 mitogen-activated protein kinase kinase kinase kinase 3
           [Homo sapiens]
          Length = 894

 Score =  142 bits (359), Expect = 5e-34
 Identities = 88/271 (32%), Positives = 152/271 (56%), Gaps = 20/271 (7%)

Query: 163 EQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSS 222
           ++D      +G G  G VYKA +V +G++ A+KVI L+   +    +  E+ ++  C   
Sbjct: 13  QEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAV-VQQEIIMMKDCKHP 71

Query: 223 YIIGFYGAFFVENRISICTEFMDGGSL-DVYR---KMPEHVLGRIAVAVVKGLTYLWSLK 278
            I+ ++G++   +++ IC EF  GGSL D+Y     + E  +  ++   ++GL YL S  
Sbjct: 72  NIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131

Query: 279 ILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIA--KTYVGTNAYMAPERISGEQYGIH 336
            +HRD+K +N+L+   G VKL DFGVS Q+  +IA  K+++GT  +MAPE  + E+ G +
Sbjct: 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGY 191

Query: 337 S---DVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVD---EDSPVLPVGEFSE 390
           +   D+W++GI+ +ELA       ++Q     L P++ L  +     +   +    ++S 
Sbjct: 192 NQLCDLWAVGITAIELA-------ELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSN 244

Query: 391 PFVHFITQCMRKQPKERPAPEELMGHPFIVQ 421
            F HF+   + K PK+RP  E+L+ HPF+ Q
Sbjct: 245 SFHHFVKMALTKNPKKRPTAEKLLQHPFVTQ 275


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score =  141 bits (356), Expect = 1e-33
 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  ELVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTGDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFVEN------RISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF  +N      ++ +  EF   GS+    K      + E  +  I   +++GL++L  
Sbjct: 87  GAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQ 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I    +P L   ++S
Sbjct: 207 DATYDFKSDLWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPAPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F  FI  C+ K   +RPA E+LM HPFI
Sbjct: 260 KKFQSFIESCLVKNHSQRPATEQLMKHPFI 289


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score =  141 bits (355), Expect = 1e-33
 Identities = 89/269 (33%), Positives = 145/269 (53%), Gaps = 21/269 (7%)

Query: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAF 231
           LG G  G VYKA +  +G + A KVI      EL+  I+ E+EIL  CD  YI+   GA+
Sbjct: 42  LGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV-EIEILATCDHPYIVKLLGAY 100

Query: 232 FVENRISICTEFMDGGSLDVY-----RKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKP 286
           + + ++ I  EF  GG++D       R + E  +  +   +++ L +L S +I+HRD+K 
Sbjct: 101 YHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKA 160

Query: 287 SNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGE-----QYGIHSDV 339
            N+L+   G ++L DFGVS + + ++ K  +++GT  +MAPE +  E      Y   +D+
Sbjct: 161 GNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADI 220

Query: 340 WSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSP-VLPVGEFSEPFVHFITQ 398
           WSLGI+ +E+A       QI+     L P+++L  I   D P +L   ++S  F  F+  
Sbjct: 221 WSLGITLIEMA-------QIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKI 273

Query: 399 CMRKQPKERPAPEELMGHPFIVQFNDGNA 427
            + K P+ RP+  +L+ HPF+       A
Sbjct: 274 ALDKNPETRPSAAQLLEHPFVSSITSNKA 302


>gi|22035600 mitogen-activated protein kinase kinase kinase kinase 2
           [Homo sapiens]
          Length = 820

 Score =  135 bits (341), Expect = 6e-32
 Identities = 86/262 (32%), Positives = 145/262 (55%), Gaps = 20/262 (7%)

Query: 172 LGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAF 231
           +G G  G VYKA    + ++ AVK++ LD   ++   +  E+ IL +C    ++ + G++
Sbjct: 22  VGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISS-LQQEITILRECRHPNVVAYIGSY 80

Query: 232 FVENRISICTEFMDGGSL-DVYRK---MPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPS 287
              +R+ IC EF  GGSL ++Y     + E  +  +    +KGL +L S   +HRD+K +
Sbjct: 81  LRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGA 140

Query: 288 NMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQYGIHS---DVWSL 342
           N+L+  +G VKL DFGVS +L  S+AK  +++GT  +MAPE  + E+ G ++   DVW+L
Sbjct: 141 NLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWAL 200

Query: 343 GISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVD---EDSPVLPVGEFSEPFVHFITQC 399
           GI+ +EL        ++Q     L P++ L  +     +   +     +++ F HF+   
Sbjct: 201 GITAIELG-------ELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLA 253

Query: 400 MRKQPKERPAPEELMGHPFIVQ 421
           + K PK+RP  E+L+ HPF  Q
Sbjct: 254 LTKNPKKRPTAEKLLQHPFTTQ 275


>gi|4826878 oxidative-stress responsive 1 [Homo sapiens]
          Length = 527

 Score =  134 bits (336), Expect = 2e-31
 Identities = 84/286 (29%), Positives = 142/286 (49%), Gaps = 35/286 (12%)

Query: 161 MNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCD 220
           +N  D   ++ +G G    V  AY  P  + +A+K I L+       +++ E++ + +C 
Sbjct: 12  INRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCH 71

Query: 221 SSYIIGFYGAFFVENRISICTEFMDGGS-LDVYRK-----------MPEHVLGRIAVAVV 268
              I+ +Y +F V++ + +  + + GGS LD+ +            + E  +  I   V+
Sbjct: 72  HPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVL 131

Query: 269 KGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLV-------NSIAKTYVGTNA 321
           +GL YL     +HRDVK  N+L+   G V++ DFGVS  L        N + KT+VGT  
Sbjct: 132 EGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPC 191

Query: 322 YMAPERISGEQ-YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDS 380
           +MAPE +   + Y   +D+WS GI+ +ELA G  PY +         P+++L   +  D 
Sbjct: 192 WMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYP-------PMKVLMLTLQNDP 244

Query: 381 PVLPVG--------EFSEPFVHFITQCMRKQPKERPAPEELMGHPF 418
           P L  G        ++ + F   I+ C++K P++RP   EL+ H F
Sbjct: 245 PSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKF 290


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score =  134 bits (336), Expect = 2e-31
 Identities = 88/270 (32%), Positives = 146/270 (54%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  EVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFV------ENRISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF        ++++ +  EF   GS+    K      + E  +  I   +++GL +L +
Sbjct: 87  GAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHA 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I     P L   ++S
Sbjct: 207 DATYDYRSDIWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPPPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F+ FI  C+ K    RP  E+L+  PFI
Sbjct: 260 KKFIDFIDTCLIKTYLSRPPTEQLLKFPFI 289


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score =  134 bits (336), Expect = 2e-31
 Identities = 88/270 (32%), Positives = 146/270 (54%), Gaps = 29/270 (10%)

Query: 170 DTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIG-FY 228
           + +G+G  G VYK  HV +G++ A+KV  +D+T + +++I  E+ +L K      I  +Y
Sbjct: 29  EVVGNGTYGQVYKGRHVKTGQLAAIKV--MDVTEDEEEEIKQEINMLKKYSHHRNIATYY 86

Query: 229 GAFFV------ENRISICTEFMDGGSLDVYRK------MPEHVLGRIAVAVVKGLTYLWS 276
           GAF        ++++ +  EF   GS+    K      + E  +  I   +++GL +L +
Sbjct: 87  GAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHA 146

Query: 277 LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAK--TYVGTNAYMAPERISGEQ-- 332
            K++HRD+K  N+L+    +VKL DFGVS QL  ++ +  T++GT  +MAPE I+ ++  
Sbjct: 147 HKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENP 206

Query: 333 ---YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFS 389
              Y   SD+WSLGI+ +E+A G  P   +        P++ L  I     P L   ++S
Sbjct: 207 DATYDYRSDIWSLGITAIEMAEGAPPLCDMH-------PMRALFLIPRNPPPRLKSKKWS 259

Query: 390 EPFVHFITQCMRKQPKERPAPEELMGHPFI 419
           + F+ FI  C+ K    RP  E+L+  PFI
Sbjct: 260 KKFIDFIDTCLIKTYLSRPPTEQLLKFPFI 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,322,965
Number of Sequences: 37866
Number of extensions: 842644
Number of successful extensions: 3949
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 702
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 1740
Number of HSP's gapped (non-prelim): 937
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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