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Search of human proteins with 21618331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21618331 carnitine acetyltransferase precursor [Homo
sapiens]
(626 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21618331 carnitine acetyltransferase precursor [Homo sapiens] 1262 0.0
gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens] 476 e-134
gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens] 476 e-134
gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens] 476 e-134
gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens] 476 e-134
gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens] 476 e-134
gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens] 476 e-134
gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens] 476 e-134
gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform ... 294 1e-79
gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [H... 281 2e-75
gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform... 279 5e-75
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s... 279 6e-75
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa... 279 6e-75
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s... 279 6e-75
gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo sap... 279 6e-75
gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo sa... 279 6e-75
gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [H... 271 2e-72
gi|4503023 carnitine O-palmitoyltransferase precursor [Homo sapi... 265 9e-71
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s... 263 4e-70
gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo sa... 262 8e-70
gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo s... 261 1e-69
gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo s... 214 2e-55
gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo s... 33 1.0
gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo s... 33 1.0
gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo s... 33 1.0
gi|38569423 ATP citrate lyase isoform 2 [Homo sapiens] 32 1.8
gi|38569421 ATP citrate lyase isoform 1 [Homo sapiens] 32 1.8
gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens] 30 5.1
>gi|21618331 carnitine acetyltransferase precursor [Homo sapiens]
Length = 626
Score = 1262 bits (3265), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSE 60
MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSE
Sbjct: 1 MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSE 60
Query: 61 EEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSP 120
EEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSP
Sbjct: 61 EEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSP 120
Query: 121 GVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSC 180
GVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSC
Sbjct: 121 GVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSC 180
Query: 181 RVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSS 240
RVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSS
Sbjct: 181 RVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSS 240
Query: 241 LQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVY 300
LQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVY
Sbjct: 241 LQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVY 300
Query: 301 RSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE 360
RSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE
Sbjct: 301 RSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE 360
Query: 361 YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKD 420
YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKD
Sbjct: 361 YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKD 420
Query: 421 FPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVK 480
FPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVK
Sbjct: 421 FPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVK 480
Query: 481 AMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMD 540
AMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMD
Sbjct: 481 AMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMD 540
Query: 541 TSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNA 600
TSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNA
Sbjct: 541 TSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNA 600
Query: 601 ARLAHYLEKALLDMRALLQSHPRAKL 626
ARLAHYLEKALLDMRALLQSHPRAKL
Sbjct: 601 ARLAHYLEKALLDMRALLQSHPRAKL 626
>gi|188595668 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 246
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 303
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 363
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 364 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 423
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 424 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 483
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 484 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 543
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 544 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603
Query: 618 LQSHP 622
P
Sbjct: 604 CSLLP 608
>gi|218931226 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 246
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 303
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 363
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 364 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 423
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 424 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 483
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 484 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 543
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 544 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603
Query: 618 LQSHP 622
P
Sbjct: 604 CSLLP 608
>gi|218931224 choline acetyltransferase isoform 3 [Homo sapiens]
Length = 666
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 44 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 103
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 104 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 163
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 164 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 223
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 224 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 282
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 283 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 339
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 340 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 399
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 400 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 459
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 460 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 519
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 520 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 579
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 580 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 639
Query: 618 LQSHP 622
P
Sbjct: 640 CSLLP 644
>gi|218931221 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 246
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 303
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 363
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 364 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 423
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 424 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 483
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 484 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 543
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 544 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603
Query: 618 LQSHP 622
P
Sbjct: 604 CSLLP 608
>gi|188595684 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 246
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 303
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 363
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 364 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 423
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 424 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 483
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 484 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 543
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 544 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603
Query: 618 LQSHP 622
P
Sbjct: 604 CSLLP 608
>gi|188595672 choline acetyltransferase isoform 1 [Homo sapiens]
Length = 630
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 246
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 303
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 363
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 364 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 423
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 424 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 483
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 484 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 543
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 544 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 603
Query: 618 LQSHP 622
P
Sbjct: 604 CSLLP 608
>gi|188595670 choline acetyltransferase isoform 2 [Homo sapiens]
Length = 748
Score = 476 bits (1224), Expect = e-134
Identities = 258/605 (42%), Positives = 382/605 (63%), Gaps = 16/605 (2%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89
+ + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L
Sbjct: 126 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 185
Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149
R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL +
Sbjct: 186 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 245
Query: 150 KVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204
K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+
Sbjct: 246 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 305
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKA 262
V QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WA+A
Sbjct: 306 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEA 364
Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
L+KD NRDS+ I++ I VCLDA D +R A Q+LHGGG N NRW
Sbjct: 365 RTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHR---ALQLLHGGGYSKNGANRW 421
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPMV-PLPMPK 379
+DK+LQF+V DG+CG+V EH+ +G +V ++++++ + +L+R+ V LP P+
Sbjct: 422 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELPAPR 481
Query: 380 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 439
+LR+ +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQL
Sbjct: 482 RLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQL 541
Query: 440 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLR 497
A+YR++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+
Sbjct: 542 AFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLK 601
Query: 498 KAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVP 557
A++A YT AI G A D HLL L+ A +P++FMD +Y ++ F LSTSQVP
Sbjct: 602 DAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQVP 661
Query: 558 AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
T+ +GPVVP+GYG CYNP I F +S+++SC ET++++ A +E++L+DMR L
Sbjct: 662 TTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRDL 721
Query: 618 LQSHP 622
P
Sbjct: 722 CSLLP 726
>gi|31542325 peroxisomal carnitine O-octanoyltransferase isoform 2
[Homo sapiens]
Length = 612
Score = 294 bits (753), Expect = 1e-79
Identities = 200/609 (32%), Positives = 317/609 (52%), Gaps = 34/609 (5%)
Query: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERR 90
+QD+LP LPVP L++SL YL++++P ++EE+ T+++V +FQ+ G+GE+L + L R
Sbjct: 16 YQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQS--GIGEKLHQKLLER 73
Query: 91 ARKTENWLSEWWLKTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVL 147
A+ NWL EWWL AYL R P V ++ P QL + + L
Sbjct: 74 AKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNL 133
Query: 148 DFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTK---KPPTHIT 204
++ ++ E +PV +G PL MNQ+ + S+C+VPG +D++ N+ +T+ + P HI
Sbjct: 134 NYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIV 193
Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP-VGILTSNHRNSWAKAY 263
V+ + F DV H +G +T ++ QL I P + LTS R WAKA
Sbjct: 194 VLCRGRAFVFDVIH-EGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAR 252
Query: 264 NTLIK-DKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322
LI D N + IQ S+ ++ + P V+ + Y +A ++ + RW
Sbjct: 253 EYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIG------DPTVRW 306
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYT-------KKPELVRSPMVPL 375
DK+ I +G G +HA + +V + YV E K E VR +
Sbjct: 307 GDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRD----I 362
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P+P++L F + ++ +DI +AK DL I F FGK K++ L PD FIQ+
Sbjct: 363 PLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQL 422
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLAYYR++G YE+A R F+ GRT+T+RS +++++ + ++M D SV ++ +
Sbjct: 423 ALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQK 482
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHFHLS 552
+ +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F LS
Sbjct: 483 MLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLS 542
Query: 553 TSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKAL 611
TS V + V+ P+V +GYG Y+ + + SA+ SC ET+A +L A
Sbjct: 543 TSLVGYLRVQGVVV--PMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAF 600
Query: 612 LDMRALLQS 620
DM L+ S
Sbjct: 601 HDMIQLMNS 609
>gi|73623030 carnitine palmitoyltransferase 1A liver isoform 1 [Homo
sapiens]
Length = 773
Score = 281 bits (718), Expect = 2e-75
Identities = 196/634 (30%), Positives = 329/634 (51%), Gaps = 49/634 (7%)
Query: 13 LGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDE 72
+G +K FS K + Q +LPRLPVP ++ +++ YL++++P++ EE++ L +
Sbjct: 151 MGMVKIFSGRKPM--LYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQD 208
Query: 73 FQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDL 132
F G+G RLQ L+ ++ N++S+WW + YL+ R P+++ S+ M +
Sbjct: 209 FAV--GLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAM-DLLYILPT 265
Query: 133 QGQLRFAAKLIEGVLDFKVMIDNETL-PVEYLGGK-PLCMNQYYQILSSCRVPGPKQDTV 190
Q A I +L ++ +D E + P+ LG PLC Q+ ++ ++ R+PG + DT+
Sbjct: 266 HIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTI 325
Query: 191 SNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWN--SSLQTNKEPV 248
+ +K HI V H ++F++ +YH DG L ++ Q+++I + S Q + +
Sbjct: 326 QHMRDSK----HIVVYHRGRYFKVWLYH-DGRLLKPREMEQQMQRILDNTSEPQPGEARL 380
Query: 249 GILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQM 308
LT+ R WA+ N+ S+ +++K+ F V LD T E+ YRS
Sbjct: 381 AALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDET-----EEGYRSEDPDTS 435
Query: 309 LHGGGSRLNSG---NRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE----- 360
+ L G +RWFDK+ F+V ++G GL EH+ A+ P + L +YV+
Sbjct: 436 MDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQ 495
Query: 361 --YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFG 418
Y + +P P +L+++I E + IE + +++ D+D F FG
Sbjct: 496 LGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFG 555
Query: 419 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTF 478
K K + SPDAF+Q+ALQLA+Y+ G+ C TYE++ R+F GRT+T+RS + +S F
Sbjct: 556 KGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDF 615
Query: 479 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIF 538
V+AM D + T Q+++L + A + H+ A+ G DRHL L + + V P +
Sbjct: 616 VRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFL- 674
Query: 539 MDTSYAIAMHFHLSTSQVPAKTDCVMF--------------FGPVVPDGYGVCYNPM-EA 583
++ + LSTSQ P + +F FGPV DGYGV Y + E
Sbjct: 675 ---KEVLSEPWRLSTSQTP-QQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGEN 730
Query: 584 HINFSLSAYNSCAETNAARLAHYLEKALLDMRAL 617
INF +S+ SC ET++ R +L++A+ D+ L
Sbjct: 731 LINFHISSKFSCPETDSHRFGRHLKEAMTDIITL 764
>gi|221316602 peroxisomal carnitine O-octanoyltransferase isoform 1
[Homo sapiens]
Length = 640
Score = 279 bits (714), Expect = 5e-75
Identities = 200/637 (31%), Positives = 317/637 (49%), Gaps = 62/637 (9%)
Query: 31 HQDALPRLPVPPLQQSLDHYLKAL----------------------------QPIVSEEE 62
+QD+LP LPVP L++SL YL+++ +P ++EE
Sbjct: 16 YQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEE 75
Query: 63 WAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPV---VIYSS 119
+ T+++V +FQ+ G+GE+L + L RA+ NWL EWWL AYL R P V ++
Sbjct: 76 YKKTEEIVQKFQS--GIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAG 133
Query: 120 PGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSS 179
P QL + + L++ ++ E +PV +G PL MNQ+ + S+
Sbjct: 134 PAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFST 193
Query: 180 CRVPGPKQDTVSNFSKTK---KPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKI 236
C+VPG +D++ N+ +T+ + P HI V+ + F DV H +G +T ++ QL I
Sbjct: 194 CKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIH-EGCLVTPPELLRQLTYI 252
Query: 237 WNSSLQTNKEP-VGILTSNHRNSWAKAYNTLIK-DKVNRDSVRSIQKSIFTVCLDATMPR 294
P + LTS R WAKA LI D N + IQ S+ ++ + P
Sbjct: 253 HKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPH 312
Query: 295 VSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTL 354
V+ + Y +A ++ + RW DK+ I +G G +HA + +V +
Sbjct: 313 VTPEDYSEIIAAILIG------DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNI 366
Query: 355 LDYVIEYT-------KKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDL 407
YV E K E VR +P+P++L F + ++ +DI +AK DL
Sbjct: 367 SYYVDEKIFQNEGRWKGSEKVRD----IPLPEELIFIVDEKVLNDINQAKAQYLREASDL 422
Query: 408 DITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDT 467
I F FGK K++ L PD FIQ+ALQLAYYR++G YE+A R F+ GRT+T
Sbjct: 423 QIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTET 482
Query: 468 IRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQA 527
+RS +++++ + ++M D SV ++ + + +A H G+ FDRHLLGL L A
Sbjct: 483 MRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIA 542
Query: 528 IEDLVSMPDIFMDTSYAIA---MHFHLSTSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEA 583
E+ + +P++F D ++ + +F LSTS V + V+ P+V +GYG Y+ +
Sbjct: 543 KEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVV--PMVHNGYGFFYHIRDD 600
Query: 584 HINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 620
+ SA+ SC ET+A +L A DM L+ S
Sbjct: 601 RFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNS 637
>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 279 bits (713), Expect = 6e-75
Identities = 203/619 (32%), Positives = 328/619 (52%), Gaps = 53/619 (8%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYN 264
+FF+L +Y +G L Q + +Q ++I + S Q +E + LT+ R WA+A
Sbjct: 340 KGRFFKLWLY--EGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQ 397
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRW 322
N+ ++ +I+++ F V LD ED + G+ +LHG N NRW
Sbjct: 398 AFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRW 452
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPL 375
FDK+ I ++G GL EHA A+ P I L ++V+ YT+ + P L
Sbjct: 453 FDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPAL 512
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P +L+++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+
Sbjct: 513 APPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQI 572
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLA++R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L
Sbjct: 573 ALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDL 632
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQ 555
+KA + H+ A+ G DRHL L L + VS P + + ++ + LSTSQ
Sbjct: 633 FQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQ 688
Query: 556 VPAKTDCVMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNA 600
+P ++ MF FGPV DGYGV Y E I F +S+ S +ETNA
Sbjct: 689 IP-QSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNA 747
Query: 601 ARLAHYLEKALLDMRALLQ 619
R +++ KALLD+ L Q
Sbjct: 748 QRFGNHIRKALLDIADLFQ 766
>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 279 bits (713), Expect = 6e-75
Identities = 203/619 (32%), Positives = 328/619 (52%), Gaps = 53/619 (8%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYN 264
+FF+L +Y +G L Q + +Q ++I + S Q +E + LT+ R WA+A
Sbjct: 340 KGRFFKLWLY--EGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQ 397
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRW 322
N+ ++ +I+++ F V LD ED + G+ +LHG N NRW
Sbjct: 398 AFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRW 452
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPL 375
FDK+ I ++G GL EHA A+ P I L ++V+ YT+ + P L
Sbjct: 453 FDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPAL 512
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P +L+++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+
Sbjct: 513 APPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQI 572
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLA++R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L
Sbjct: 573 ALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDL 632
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQ 555
+KA + H+ A+ G DRHL L L + VS P + + ++ + LSTSQ
Sbjct: 633 FQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQ 688
Query: 556 VPAKTDCVMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNA 600
+P ++ MF FGPV DGYGV Y E I F +S+ S +ETNA
Sbjct: 689 IP-QSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNA 747
Query: 601 ARLAHYLEKALLDMRALLQ 619
R +++ KALLD+ L Q
Sbjct: 748 QRFGNHIRKALLDIADLFQ 766
>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 279 bits (713), Expect = 6e-75
Identities = 203/619 (32%), Positives = 328/619 (52%), Gaps = 53/619 (8%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYN 264
+FF+L +Y +G L Q + +Q ++I + S Q +E + LT+ R WA+A
Sbjct: 340 KGRFFKLWLY--EGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQ 397
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRW 322
N+ ++ +I+++ F V LD ED + G+ +LHG N NRW
Sbjct: 398 AFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRW 452
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPL 375
FDK+ I ++G GL EHA A+ P I L ++V+ YT+ + P L
Sbjct: 453 FDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPAL 512
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P +L+++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+
Sbjct: 513 APPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQI 572
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLA++R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L
Sbjct: 573 ALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDL 632
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQ 555
+KA + H+ A+ G DRHL L L + VS P + + ++ + LSTSQ
Sbjct: 633 FQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQ 688
Query: 556 VPAKTDCVMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNA 600
+P ++ MF FGPV DGYGV Y E I F +S+ S +ETNA
Sbjct: 689 IP-QSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNA 747
Query: 601 ARLAHYLEKALLDMRALLQ 619
R +++ KALLD+ L Q
Sbjct: 748 QRFGNHIRKALLDIADLFQ 766
>gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 279 bits (713), Expect = 6e-75
Identities = 203/619 (32%), Positives = 328/619 (52%), Gaps = 53/619 (8%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYN 264
+FF+L +Y +G L Q + +Q ++I + S Q +E + LT+ R WA+A
Sbjct: 340 KGRFFKLWLY--EGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQ 397
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRW 322
N+ ++ +I+++ F V LD ED + G+ +LHG N NRW
Sbjct: 398 AFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRW 452
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPL 375
FDK+ I ++G GL EHA A+ P I L ++V+ YT+ + P L
Sbjct: 453 FDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPAL 512
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P +L+++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+
Sbjct: 513 APPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQI 572
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLA++R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L
Sbjct: 573 ALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDL 632
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQ 555
+KA + H+ A+ G DRHL L L + VS P + + ++ + LSTSQ
Sbjct: 633 FQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQ 688
Query: 556 VPAKTDCVMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNA 600
+P ++ MF FGPV DGYGV Y E I F +S+ S +ETNA
Sbjct: 689 IP-QSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNA 747
Query: 601 ARLAHYLEKALLDMRALLQ 619
R +++ KALLD+ L Q
Sbjct: 748 QRFGNHIRKALLDIADLFQ 766
>gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo
sapiens]
Length = 772
Score = 279 bits (713), Expect = 6e-75
Identities = 203/619 (32%), Positives = 328/619 (52%), Gaps = 53/619 (8%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYN 264
+FF+L +Y +G L Q + +Q ++I + S Q +E + LT+ R WA+A
Sbjct: 340 KGRFFKLWLY--EGARLLKPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQ 397
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRW 322
N+ ++ +I+++ F V LD ED + G+ +LHG N NRW
Sbjct: 398 AFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRW 452
Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPL 375
FDK+ I ++G GL EHA A+ P I L ++V+ YT+ + P L
Sbjct: 453 FDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPAL 512
Query: 376 PMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQM 435
P +L+++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+
Sbjct: 513 APPTRLQWDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQI 572
Query: 436 ALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVEL 495
ALQLA++R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L
Sbjct: 573 ALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDL 632
Query: 496 LRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQ 555
+KA + H+ A+ G DRHL L L + VS P + + ++ + LSTSQ
Sbjct: 633 FQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQ 688
Query: 556 VPAKTDCVMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNA 600
+P ++ MF FGPV DGYGV Y E I F +S+ S +ETNA
Sbjct: 689 IP-QSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNA 747
Query: 601 ARLAHYLEKALLDMRALLQ 619
R +++ KALLD+ L Q
Sbjct: 748 QRFGNHIRKALLDIADLFQ 766
>gi|73623028 carnitine palmitoyltransferase 1A liver isoform 2 [Homo
sapiens]
Length = 756
Score = 271 bits (692), Expect = 2e-72
Identities = 191/615 (31%), Positives = 317/615 (51%), Gaps = 49/615 (7%)
Query: 13 LGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDE 72
+G +K FS K + Q +LPRLPVP ++ +++ YL++++P++ EE++ L +
Sbjct: 151 MGMVKIFSGRKPM--LYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQD 208
Query: 73 FQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDL 132
F G+G RLQ L+ ++ N++S+WW + YL+ R P+++ S+ M +
Sbjct: 209 FAV--GLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAM-DLLYILPT 265
Query: 133 QGQLRFAAKLIEGVLDFKVMIDNETL-PVEYLGGK-PLCMNQYYQILSSCRVPGPKQDTV 190
Q A I +L ++ +D E + P+ LG PLC Q+ ++ ++ R+PG + DT+
Sbjct: 266 HIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTI 325
Query: 191 SNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWN--SSLQTNKEPV 248
+ +K HI V H ++F++ +YH DG L ++ Q+++I + S Q + +
Sbjct: 326 QHMRDSK----HIVVYHRGRYFKVWLYH-DGRLLKPREMEQQMQRILDNTSEPQPGEARL 380
Query: 249 GILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQM 308
LT+ R WA+ N+ S+ +++K+ F V LD T E+ YRS
Sbjct: 381 AALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDET-----EEGYRSEDPDTS 435
Query: 309 LHGGGSRLNSG---NRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE----- 360
+ L G +RWFDK+ F+V ++G GL EH+ A+ P + L +YV+
Sbjct: 436 MDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQ 495
Query: 361 --YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFG 418
Y + +P P +L+++I E + IE + +++ D+D F FG
Sbjct: 496 LGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFG 555
Query: 419 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTF 478
K K + SPDAF+Q+ALQLA+Y+ G+ C TYE++ R+F GRT+T+RS + +S F
Sbjct: 556 KGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDF 615
Query: 479 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIF 538
V+AM D + T Q+++L + A + H+ A+ G DRHL L + + V P +
Sbjct: 616 VRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFL- 674
Query: 539 MDTSYAIAMHFHLSTSQVPAKTDCVMF--------------FGPVVPDGYGVCYNPM-EA 583
++ + LSTSQ P + +F FGPV DGYGV Y + E
Sbjct: 675 ---KEVLSEPWRLSTSQTP-QQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGEN 730
Query: 584 HINFSLSAYNSCAET 598
INF +S+ SC ET
Sbjct: 731 LINFHISSKFSCPET 745
>gi|4503023 carnitine O-palmitoyltransferase precursor [Homo
sapiens]
Length = 658
Score = 265 bits (677), Expect = 9e-71
Identities = 194/628 (30%), Positives = 311/628 (49%), Gaps = 69/628 (10%)
Query: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER- 89
+QD+LPRLP+P L+ ++ YL A +P++++ ++ T+Q F+ G+G+ L + L
Sbjct: 45 YQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFE--NGIGKELHEQLVAL 102
Query: 90 -RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQLR 137
+ K +++S W YL R VV+ +P + PK ++ D +R
Sbjct: 103 DKQNKHTSYISGPWFDM-YLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIR 161
Query: 138 FAAKLIEGVLD---------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQIL 177
F L G+L+ FK +I + + G PL M+QY+++
Sbjct: 162 FLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLF 221
Query: 178 SSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIW 237
+S R+P P +D + K + H+ V+ F+ DV DG ++ +I L+ I
Sbjct: 222 NSTRLPKPSRDELFTDDKAR----HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYIL 277
Query: 238 NSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSE 297
+ S + P+ LTS +R+ WA+ L+ N +S+R + ++F +CLD P + +
Sbjct: 278 SDSSPAPEFPLAYLTSENRDIWAELRQKLMSSG-NEESLRKVDSAVFCLCLD-DFP-IKD 334
Query: 298 DVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDY 357
V+ SH MLHG G+ NRWFDK+ I+A+DGS + +EH+ +G ++ +
Sbjct: 335 LVHLSH---NMLHGDGT-----NRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNE 386
Query: 358 VIEYTKKPELVRSPMVPLPMP-----KKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVM 412
V + + + V P +KL F +T +K+ I AK+ ++ L I +
Sbjct: 387 VFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTDALKTGITAAKEKFDATMKTLTIDCV 446
Query: 413 VFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSAS 472
F GK+F K +KLSPDA Q+A Q+A+ R YGQ ATYES S F GRT+TIR AS
Sbjct: 447 QFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPAS 506
Query: 473 MDSLTFVKAMDDSSVTE---HQKVELLRKAVQA---HRGYTDRAIRGEAFDRHLLGLKLQ 526
+ + K ++ V E H EL + V+ H T A G+ FDRHL L+
Sbjct: 507 V----YTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHL 562
Query: 527 AIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHIN 586
A + +P++++D +Y H LSTS + + + F PVV DG+GV Y + I
Sbjct: 563 AAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFGVGYAVHDNWIG 622
Query: 587 FSLSAYNSCAETNAARLAHYLEKALLDM 614
++S+Y NA +EKAL DM
Sbjct: 623 CNVSSYPG---RNAREFLQCVEKALEDM 647
>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
sapiens]
Length = 738
Score = 263 bits (672), Expect = 4e-70
Identities = 196/601 (32%), Positives = 316/601 (52%), Gaps = 53/601 (8%)
Query: 50 YLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQ 109
YL++++P++ +EE+ + L EFQ RLQK L ++ N++S+WW + YL+
Sbjct: 154 YLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKSWWASNYVSDWWEEYIYLR 211
Query: 110 YRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLDFKVMIDNETL-PVEYLGG 165
R P+++ S+ VM D V ++ AA+L I ++ ++ +D E + PV LG
Sbjct: 212 GRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGI 267
Query: 166 KPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLT 225
P+C Q ++ ++ R+PG D + + S ++ H+ V H +FF+L +Y +G L
Sbjct: 268 VPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYHKGRFFKLWLY--EGARLL 321
Query: 226 ADQ-IFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKS 282
Q + +Q ++I + S Q +E + LT+ R WA+A N+ ++ +I+++
Sbjct: 322 KPQDLEMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERA 381
Query: 283 IFTVCLDATMPRVS-EDVYRSHVAGQ-MLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLV 340
F V LD ED + G+ +LHG N NRWFDK+ I ++G GL
Sbjct: 382 AFFVALDEESYSYDPEDEASLSLYGKALLHG-----NCYNRWFDKSFTLISFKNGQLGLN 436
Query: 341 YEHAAAEGPPIVTLLDYVIE-------YTKKPELVRSPMVPLPMPKKLRFNITPEIKSDI 393
EHA A+ P I L ++V+ YT+ + P L P +L+++I + ++ I
Sbjct: 437 AEHAWADAPIIGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVI 496
Query: 394 EKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYE 453
E + Q + D+++ F FGK K + SPDAF+Q+ALQLA++R G+ C TYE
Sbjct: 497 ESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYE 556
Query: 454 SASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRG 513
++ RMF GRT+T+RS + +S FV+AM + S T+ +L +KA + H+ A+ G
Sbjct: 557 ASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTG 616
Query: 514 EAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMF-------- 565
DRHL L L + VS P + + ++ + LSTSQ+P ++ MF
Sbjct: 617 AGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQIP-QSQIRMFDPEQHPNH 671
Query: 566 ------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALL 618
FGPV DGYGV Y E I F +S+ S +ETNA R +++ KALLD+ L
Sbjct: 672 LGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLF 731
Query: 619 Q 619
Q
Sbjct: 732 Q 732
>gi|22748777 carnitine palmitoyltransferase 1C isoform 2 [Homo
sapiens]
Length = 803
Score = 262 bits (669), Expect = 8e-70
Identities = 194/628 (30%), Positives = 327/628 (52%), Gaps = 66/628 (10%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEF---QASGGVGERLQKG 86
++Q +LPR PVP +Q ++ YL++++PI+S+E++ T L EF QAS LQ
Sbjct: 166 SYQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQAS-----LLQWY 220
Query: 87 LERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQG---QLRFAAKLI 143
L ++ N++S+WW + YL+ R P+++ S+ +M DF+ + Q A +
Sbjct: 221 LRLKSWWASNYVSDWWEEFVYLRSRNPLMVNSNYYMM----DFLYVTPTPLQAARAGNAV 276
Query: 144 EGVLDFKVMIDNETLPVEYLGG-KPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTH 202
+L ++ ++ + +P L G +PLC QY +I ++ R+PG ++D + + ++ H
Sbjct: 277 HALLLYRHRLNRQEIPPTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQ----H 332
Query: 203 ITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWA 260
+ V H +FF + HS + L+ + Q ++I + S ++E + LT+ R +WA
Sbjct: 333 VAVFHRGRFFRMGT-HSRNSLLSPRALEQQFQRILDDPSPACPHEEHLAALTAAPRGTWA 391
Query: 261 KAYNTLIKDKVNRDSVRSIQKSIFTVCLDATM-------PRVSEDVYRSHVAGQMLHGGG 313
+ +L +++ +++ + F V LDA P S D Y A +L G G
Sbjct: 392 QVRTSLKTQAA--EALEAVEGAAFFVSLDAEPAGLTREDPAASLDAY----AHALLAGRG 445
Query: 314 SRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPE 366
+RWFDK+ IV +G GL EH+ A+ P + ++ + Y+
Sbjct: 446 H-----DRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGH 500
Query: 367 LVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEK 426
P LP P++L++++ +I S I A + I+ +++D V+ F FGK F +
Sbjct: 501 CKGHPDPTLPQPQRLQWDLPDQIHSSISLALRGAKILSENVDCHVVPFSLFGKSFIRRCH 560
Query: 427 LSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSS 486
LS D+FIQ+ALQLA++R GQ C TYESA R+F GRT+T+RS + ++ FV+AM+D
Sbjct: 561 LSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKE 620
Query: 487 VTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA 546
T+ Q + L R AV H+ A+ G+ DRHL L + + + + F+ + +
Sbjct: 621 KTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYI--VSRFLHLQSPFLTQVH--S 676
Query: 547 MHFHLSTSQVPAK----------TDCVMF---FGPVVPDGYGVCYNPM-EAHINFSLSAY 592
+ LSTSQ+P + D V FGP GYGV Y M + I F +S+
Sbjct: 677 EQWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSK 736
Query: 593 NSCAETNAARLAHYLEKALLDMRALLQS 620
S +T++ RL ++E ALLD+ +L Q+
Sbjct: 737 KSSTKTDSHRLGQHIEDALLDVASLFQA 764
>gi|209862905 carnitine palmitoyltransferase 1C isoform 1 [Homo
sapiens]
Length = 792
Score = 261 bits (667), Expect = 1e-69
Identities = 191/625 (30%), Positives = 323/625 (51%), Gaps = 71/625 (11%)
Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEF---QASGGVGERLQKG 86
++Q +LPR PVP +Q ++ YL++++PI+S+E++ T L EF QAS LQ
Sbjct: 166 SYQRSLPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQAS-----LLQWY 220
Query: 87 LERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGV 146
L ++ N++S+WW + YL+ R P+++ S+ +M + A + +
Sbjct: 221 LRLKSWWASNYVSDWWEEFVYLRSRNPLMVNSNYYMMAAR------------AGNAVHAL 268
Query: 147 LDFKVMIDNETLPVEYLGG-KPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITV 205
L ++ ++ + +P L G +PLC QY +I ++ R+PG ++D + + ++ H+ V
Sbjct: 269 LLYRHRLNRQEIPPTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQ----HVAV 324
Query: 206 VHNYQFFELDVYHSDGTPLTADQIFVQLEKIWN--SSLQTNKEPVGILTSNHRNSWAKAY 263
H +FF + HS + L+ + Q ++I + S ++E + LT+ R +WA+
Sbjct: 325 FHRGRFFRMGT-HSRNSLLSPRALEQQFQRILDDPSPACPHEEHLAALTAAPRGTWAQVR 383
Query: 264 NTLIKDKVNRDSVRSIQKSIFTVCLDATM-------PRVSEDVYRSHVAGQMLHGGGSRL 316
+L +++ +++ + F V LDA P S D Y A +L G G
Sbjct: 384 TSLKTQAA--EALEAVEGAAFFVSLDAEPAGLTREDPAASLDAY----AHALLAGRGH-- 435
Query: 317 NSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE-------YTKKPELVR 369
+RWFDK+ IV +G GL EH+ A+ P + ++ + Y+
Sbjct: 436 ---DRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGHCKG 492
Query: 370 SPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSP 429
P LP P++L++++ +I S I A + I+ +++D V+ F FGK F + LS
Sbjct: 493 HPDPTLPQPQRLQWDLPDQIHSSISLALRGAKILSENVDCHVVPFSLFGKSFIRRCHLSS 552
Query: 430 DAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTE 489
D+FIQ+ALQLA++R GQ C TYESA R+F GRT+T+RS + ++ FV+AM+D T+
Sbjct: 553 DSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTD 612
Query: 490 HQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHF 549
Q + L R AV H+ A+ G+ DRHL L + + + + F+ + + +
Sbjct: 613 PQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYI--VSRFLHLQSPFLTQVH--SEQW 668
Query: 550 HLSTSQVPAK----------TDCVMF---FGPVVPDGYGVCYNPM-EAHINFSLSAYNSC 595
LSTSQ+P + D V FGP GYGV Y M + I F +S+ S
Sbjct: 669 QLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSKKSS 728
Query: 596 AETNAARLAHYLEKALLDMRALLQS 620
+T++ RL ++E ALLD+ +L Q+
Sbjct: 729 TKTDSHRLGQHIEDALLDVASLFQA 753
>gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo
sapiens]
Length = 691
Score = 214 bits (545), Expect = 2e-55
Identities = 175/612 (28%), Positives = 285/612 (46%), Gaps = 120/612 (19%)
Query: 32 QDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRA 91
Q +LP+LPVP + ++ YL++++P++ +EE+ + L EFQ RLQK L ++
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMELLAKEFQDK--TAPRLQKYLVLKS 227
Query: 92 RKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL---IEGVLD 148
N++S+WW + YL+ R P+++ S+ VM D V ++ AA+L I ++
Sbjct: 228 WWASNYVSDWWEEYIYLRGRSPLMVNSNYYVM----DLVLIKNTDVQAARLGNIIHAMIM 283
Query: 149 FKVMIDNETL-PVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVH 207
++ +D E + PV LG P+C Q ++ ++ R+PG D + + S ++ H+ V H
Sbjct: 284 YRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSR----HVAVYH 339
Query: 208 NYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLI 267
+FF+L +Y +L ++ +L L N N W TLI
Sbjct: 340 KGRFFKLWLYEG-----------ARLLSLYGKAL---------LHGNCYNRWFDKSFTLI 379
Query: 268 KDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTL 327
K G LN+ + W D +
Sbjct: 380 SFK----------------------------------------NGQLGLNAEHAWADAPI 399
Query: 328 -----QFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPMVPLPMPKKLR 382
+F++ D + + YT+ + P L P +L+
Sbjct: 400 IGHLWEFVLGTD---------------------SFHLGYTETGHCLGKPNPALAPPTRLQ 438
Query: 383 FNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYY 442
++I + ++ IE + Q + D+++ F FGK K + SPDAF+Q+ALQLA++
Sbjct: 439 WDIPKQCQAVIESSYQVAKALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHF 498
Query: 443 RIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQA 502
R G+ C TYE++ RMF GRT+T+RS + +S FV+AM + S T+ +L +KA +
Sbjct: 499 RDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKK 558
Query: 503 HRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDC 562
H+ A+ G DRHL L L + VS P + + ++ + LSTSQ+P ++
Sbjct: 559 HQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFL----AEVLSEPWRLSTSQIP-QSQI 613
Query: 563 VMF--------------FGPVVPDGYGVCYN-PMEAHINFSLSAYNSCAETNAARLAHYL 607
MF FGPV DGYGV Y E I F +S+ S +ETNA R +++
Sbjct: 614 RMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHI 673
Query: 608 EKALLDMRALLQ 619
KALLD+ L Q
Sbjct: 674 RKALLDIADLFQ 685
>gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo
sapiens]
Length = 1020
Score = 32.7 bits (73), Expect = 1.0
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 216 VYHSDGTPL---------TADQIFVQL--EKIWNSSLQTNKEPVGILTSNHRNSWAKAYN 264
VY DGTP+ D+ F+Q EK + KE + I+ S N K N
Sbjct: 688 VYTKDGTPIFTLRDLVLWALDESFLQRDSEKQKQDAAPVGKEQI-IVESMEENPRMKVKN 746
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCL 288
L V DS+ I KS+ T+ L
Sbjct: 747 RLFAKSVTSDSLDGIDKSLLTLIL 770
>gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo
sapiens]
Length = 1020
Score = 32.7 bits (73), Expect = 1.0
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 216 VYHSDGTPL---------TADQIFVQL--EKIWNSSLQTNKEPVGILTSNHRNSWAKAYN 264
VY DGTP+ D+ F+Q EK + KE + I+ S N K N
Sbjct: 688 VYTKDGTPIFTLRDLVLWALDESFLQRDSEKQKQDAAPVGKEQI-IVESMEENPRMKVKN 746
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCL 288
L V DS+ I KS+ T+ L
Sbjct: 747 RLFAKSVTSDSLDGIDKSLLTLIL 770
>gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo
sapiens]
Length = 1020
Score = 32.7 bits (73), Expect = 1.0
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 216 VYHSDGTPL---------TADQIFVQL--EKIWNSSLQTNKEPVGILTSNHRNSWAKAYN 264
VY DGTP+ D+ F+Q EK + KE + I+ S N K N
Sbjct: 688 VYTKDGTPIFTLRDLVLWALDESFLQRDSEKQKQDAAPVGKEQI-IVESMEENPRMKVKN 746
Query: 265 TLIKDKVNRDSVRSIQKSIFTVCL 288
L V DS+ I KS+ T+ L
Sbjct: 747 RLFAKSVTSDSLDGIDKSLLTLIL 770
>gi|38569423 ATP citrate lyase isoform 2 [Homo sapiens]
Length = 1091
Score = 32.0 bits (71), Expect = 1.8
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 33/140 (23%)
Query: 250 ILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTV------CLDATMPRVS------- 296
++T++H + + A+NT+I + +D V S+ + T+ LDA S
Sbjct: 885 MVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGI 944
Query: 297 ---EDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVT 353
E V + G+++ G G R+ S N + ++ + +D V +H P
Sbjct: 945 IPMEFVNKMKKEGKLIMGIGHRVKSIN---NPDMRVQILKD----YVRQHF-----PATP 992
Query: 354 LLDYVIEY-----TKKPELV 368
LLDY +E +KKP L+
Sbjct: 993 LLDYALEVEKITTSKKPNLI 1012
>gi|38569421 ATP citrate lyase isoform 1 [Homo sapiens]
Length = 1101
Score = 32.0 bits (71), Expect = 1.8
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 33/140 (23%)
Query: 250 ILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTV------CLDATMPRVS------- 296
++T++H + + A+NT+I + +D V S+ + T+ LDA S
Sbjct: 895 MVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGI 954
Query: 297 ---EDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVT 353
E V + G+++ G G R+ S N + ++ + +D V +H P
Sbjct: 955 IPMEFVNKMKKEGKLIMGIGHRVKSIN---NPDMRVQILKD----YVRQHF-----PATP 1002
Query: 354 LLDYVIEY-----TKKPELV 368
LLDY +E +KKP L+
Sbjct: 1003 LLDYALEVEKITTSKKPNLI 1022
>gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens]
Length = 908
Score = 30.4 bits (67), Expect = 5.1
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 288 LDATMPRVSEDVYRSHVAGQMLHGGGSRLNS 318
LD P+V +D+Y++H+ G GS+++S
Sbjct: 337 LDIMEPKVPDDIYKTHLENNRFGGSGSQVDS 367
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,570,688
Number of Sequences: 37866
Number of extensions: 1053533
Number of successful extensions: 2470
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2315
Number of HSP's gapped (non-prelim): 30
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.