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Search of human proteins with 21536436
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens] 890 0.0
gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens] 878 0.0
gi|29826279 tubby isoform b [Homo sapiens] 458 e-129
gi|19923167 tubby isoform a [Homo sapiens] 457 e-128
gi|157266334 tubby like protein 1 [Homo sapiens] 365 e-101
gi|238859545 tubby like protein 2 [Homo sapiens] 274 1e-73
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 75 1e-13
gi|157504499 ankyrin repeat domain 47 [Homo sapiens] 35 0.18
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 35 0.18
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens] 34 0.30
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 34 0.30
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] 34 0.30
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 33 0.40
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 33 0.40
gi|221136781 S1 RNA binding domain 1 [Homo sapiens] 33 0.68
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 32 0.88
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 32 0.88
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 32 1.2
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 32 1.2
gi|9966761 choroideremia isoform a [Homo sapiens] 31 2.0
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 31 2.0
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 31 2.6
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 31 2.6
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 31 2.6
gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens] 31 2.6
gi|49170034 integrin, alpha 8 [Homo sapiens] 31 2.6
gi|110832843 TBP-associated factor 4 [Homo sapiens] 30 3.4
gi|37595553 ring finger protein 111 [Homo sapiens] 30 3.4
gi|149773449 zinc finger protein 862 [Homo sapiens] 30 3.4
gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens] 30 3.4
>gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]
Length = 442
Score = 890 bits (2300), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA
Sbjct: 1 MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
Query: 61 KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS
Sbjct: 61 KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
Query: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN
Sbjct: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
Query: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK
Sbjct: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
Query: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR
Sbjct: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
Query: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE
Sbjct: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
Query: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY
Sbjct: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
Query: 421 PLCAVQAFGIGLSSFDSKLACE 442
PLCAVQAFGIGLSSFDSKLACE
Sbjct: 421 PLCAVQAFGIGLSSFDSKLACE 442
>gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
Length = 501
Score = 878 bits (2269), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA
Sbjct: 1 MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
Query: 61 KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS
Sbjct: 61 KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
Query: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN
Sbjct: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
Query: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK
Sbjct: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
Query: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR
Sbjct: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
Query: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE
Sbjct: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
Query: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY
Sbjct: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
Query: 421 PLCAVQAFGIGLSSFD 436
PLCAVQAFGIGLSSFD
Sbjct: 421 PLCAVQAFGIGLSSFD 436
>gi|29826279 tubby isoform b [Homo sapiens]
Length = 506
Score = 458 bits (1179), Expect = e-129
Identities = 251/497 (50%), Positives = 322/497 (64%), Gaps = 71/497 (14%)
Query: 14 SVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVN 73
SV +E +RQ KLD QR LLE++Q+KKR EP MVQ N + R R + R S+EQ PLV
Sbjct: 13 SVLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVE 72
Query: 74 CHTPHSNVILH------------------------------------------------- 84
+ S +
Sbjct: 73 SYLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHK 132
Query: 85 GIDGPAAVLKP-DEVHAPSVSSSVVEED-AENTVDTASKPG-------LQERLQKHDISE 135
G GPAA+ + E P +V + D A++ +TA+ G L+ +Q+ IS
Sbjct: 133 GTSGPAALAEDKSEAQGPVQILTVGQSDHAQDAGETAAGGGERPSGQDLRATMQRKGISS 192
Query: 136 SVNFDE----ETDGISQSACLE---RPNSASSQNSTDTGTSGSATAA--QPADNLLGDID 186
S++FDE E + S S+ L RP+SA+S+ S S + A QP D ++
Sbjct: 193 SMSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDV---EVQ 249
Query: 187 DLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKT 246
DLE+F PAPQG+T++CRI RDK+GMDRG++PTY+++L++E+ +K+FLLA RKRKKSKT
Sbjct: 250 DLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKT 309
Query: 247 ANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHT-RQELAA 305
+NYLIS+DP DLSR G+SY+GKLRSNLMGTKFTVYD G+ P K + T RQELAA
Sbjct: 310 SNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAA 369
Query: 306 ISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVELHNKA 365
+ YETNVLGFKGPRKMSVI+PGM + H+++ +P+N H++LL+RWQN+ E+++EL NK
Sbjct: 370 VCYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKT 429
Query: 366 PVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAV 425
PVWN DTQSYVLNF GRVTQASVKNFQI+H NDPDYIVMQFGRVA+DVFT+DYNYPLCA+
Sbjct: 430 PVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCAL 489
Query: 426 QAFGIGLSSFDSKLACE 442
QAF I LSSFDSKLACE
Sbjct: 490 QAFAIALSSFDSKLACE 506
>gi|19923167 tubby isoform a [Homo sapiens]
Length = 561
Score = 457 bits (1175), Expect = e-128
Identities = 250/496 (50%), Positives = 321/496 (64%), Gaps = 71/496 (14%)
Query: 15 VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVNC 74
V +E +RQ KLD QR LLE++Q+KKR EP MVQ N + R R + R S+EQ PLV
Sbjct: 69 VLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVES 128
Query: 75 HTPHSNVILH-------------------------------------------------G 85
+ S + G
Sbjct: 129 YLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKG 188
Query: 86 IDGPAAVLKP-DEVHAPSVSSSVVEED-AENTVDTASKPG-------LQERLQKHDISES 136
GPAA+ + E P +V + D A++ +TA+ G L+ +Q+ IS S
Sbjct: 189 TSGPAALAEDKSEAQGPVQILTVGQSDHAQDAGETAAGGGERPSGQDLRATMQRKGISSS 248
Query: 137 VNFDE----ETDGISQSACLE---RPNSASSQNSTDTGTSGSATAA--QPADNLLGDIDD 187
++FDE E + S S+ L RP+SA+S+ S S + A QP D ++ D
Sbjct: 249 MSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDV---EVQD 305
Query: 188 LEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKTA 247
LE+F PAPQG+T++CRI RDK+GMDRG++PTY+++L++E+ +K+FLLA RKRKKSKT+
Sbjct: 306 LEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTS 365
Query: 248 NYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHT-RQELAAI 306
NYLIS+DP DLSR G+SY+GKLRSNLMGTKFTVYD G+ P K + T RQELAA+
Sbjct: 366 NYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAV 425
Query: 307 SYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVELHNKAP 366
YETNVLGFKGPRKMSVI+PGM + H+++ +P+N H++LL+RWQN+ E+++EL NK P
Sbjct: 426 CYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKTP 485
Query: 367 VWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAVQ 426
VWN DTQSYVLNF GRVTQASVKNFQI+H NDPDYIVMQFGRVA+DVFT+DYNYPLCA+Q
Sbjct: 486 VWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQ 545
Query: 427 AFGIGLSSFDSKLACE 442
AF I LSSFDSKLACE
Sbjct: 546 AFAIALSSFDSKLACE 561
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 365 bits (937), Expect = e-101
Identities = 175/284 (61%), Positives = 223/284 (78%), Gaps = 3/284 (1%)
Query: 159 SSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLF 218
S+Q G + A + ++D+ +FV PAPQG TVRCR+ RDK+GMDRG++
Sbjct: 262 SNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMY 321
Query: 219 PTYYMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKF 278
P+Y+++L+ E+ K+FLLA RKRK+SKTANYLISIDP +LSR GE+++GKLRSNL+G +F
Sbjct: 322 PSYFLHLDTEK--KVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRF 379
Query: 279 TVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQ 338
TV+D G P +G A RQELAA+ YETNVLGF+GPR+M+VIIPGM+ ++++P +
Sbjct: 380 TVFDNGQNPQRGYS-TNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIR 438
Query: 339 PQNNHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKND 398
P+N D LL RWQN+T+E+L+ELHNK PVWN D+ SY LNF+GRVTQASVKNFQIVH +D
Sbjct: 439 PRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADD 498
Query: 399 PDYIVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFDSKLACE 442
PDYIV+QFGRVA+D FTLDY YPLCA+QAF I LSSFD KLACE
Sbjct: 499 PDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFDGKLACE 542
>gi|238859545 tubby like protein 2 [Homo sapiens]
Length = 520
Score = 274 bits (700), Expect = 1e-73
Identities = 146/335 (43%), Positives = 205/335 (61%), Gaps = 9/335 (2%)
Query: 111 DAENTVDTASKPGLQ-----ERL--QKHDISESVNFDEETDGISQSACL--ERPNSASSQ 161
DA + + PG+ E L QK + E E+ G + SA E + +
Sbjct: 186 DAHKSPNMGPNPGMDGDCVYENLAFQKEEDLEKKREASESTGTNSSAAHNEELSKALKGE 245
Query: 162 NSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTY 221
TD+ + G +D+E +V PA G ++C + RDK G+D+GLFP Y
Sbjct: 246 GGTDSDHMRHEASLAIRSPCPGLEEDMEAYVLRPALPGTMMQCYLTRDKHGVDKGLFPLY 305
Query: 222 YMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVY 281
Y+YLE ++ + FLLA RKR++SKT+NYLIS+DP LSR+G+++VGK+RSN+ TKFT++
Sbjct: 306 YLYLETSDSLQRFLLAGRKRRRSKTSNYLISLDPTHLSRDGDNFVGKVRSNVFSTKFTIF 365
Query: 282 DRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQN 341
D G+ P + A RQEL A+ YE NVLG+ GPRKM+VI+PG +++I QP N
Sbjct: 366 DNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTVILPGTNSQNQRINVQPLN 425
Query: 342 NHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDY 401
+SLLSR+Q + L+ LHNK P W+ + Y LNF GRVT+ASVKNFQIV ++
Sbjct: 426 EQESLLSRYQRGDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEH 485
Query: 402 IVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFD 436
+V+QFGRV D FT+D+ +P +QAF I LSSF+
Sbjct: 486 LVLQFGRVGPDTFTMDFCFPFSPLQAFSICLSSFN 520
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/41 (51%), Positives = 27/41 (65%)
Query: 15 VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEA 55
+ E+ MR KL+ QR L EK+QR+KR E MVQ NP+A
Sbjct: 12 ILGHELAAMRLQKLEQQRRLFEKKQRQKRQELLMVQANPDA 52
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 75.1 bits (183), Expect = 1e-13
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 3/77 (3%)
Query: 363 NKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPL 422
NK P+WN TQ Y L+F GRVTQ S KNFQI + VMQFGR+ + LD+ YP
Sbjct: 1469 NKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ---VMQFGRIDGSAYILDFQYPF 1525
Query: 423 CAVQAFGIGLSSFDSKL 439
AVQAF + L++ +L
Sbjct: 1526 SAVQAFAVALANVTQRL 1542
Score = 30.8 bits (68), Expect = 2.6
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 13/63 (20%)
Query: 264 SYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSV 323
+Y+ ++ SN+ GTKF + GL AA L A+ Y+T++L + PR+M++
Sbjct: 594 NYLAQVTSNIWGTKFKIV----------GL--AAFLPTNLGAVIYKTSLLHLQ-PRQMTI 640
Query: 324 IIP 326
+P
Sbjct: 641 YLP 643
>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
Length = 821
Score = 34.7 bits (78), Expect = 0.18
Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 30/208 (14%)
Query: 18 EEMMKMRQAKLDYQRLLLEK-RQRKKRLEPFMVQPNPEARLRRAKPRASDEQTP------ 70
E +++ +A L++QR + E R R + LE A RA+ R + QTP
Sbjct: 352 ERELELLRASLEHQRGVSELLRGRLRELEEAREAAEEAAAGARAQLREATTQTPWSCAEK 411
Query: 71 LVNCHTPHSNVILHGIDGPAAVLKPDEVHAPS--VSSSVVEEDAENTVDTASKP------ 122
+P L P + + D AP+ + S + + D +S P
Sbjct: 412 AAQTESPAEAPSLTQESSPGS-MDGDRAVAPAGILKSIMKKRDGTPGAQPSSGPKSLQFV 470
Query: 123 ----GLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPA 178
G E D S+S DG S++ E P S+S G S S T P+
Sbjct: 471 GVLNGEYESSSSEDASDS-------DGDSENGGAEPPGSSSGSGDDSGGGSDSGTPGPPS 523
Query: 179 DNLLGDIDDLEDFVYSPAPQGVTVRCRI 206
GDI D E + Q RC +
Sbjct: 524 G---GDIRDPEPEAEAEPQQVAQGRCEL 548
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 34.7 bits (78), Expect = 0.18
Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 5/112 (4%)
Query: 86 IDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDG 145
+D P A + + P+ + V+E+ + + + + GL+ QK +++ FD E
Sbjct: 2301 LDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKEGGLKLTFQKQGLAQKRPFDGEDGA 2360
Query: 146 ISQSACLERPNSASSQNSTD-----TGTSGSATAAQPADNLLGDIDDLEDFV 192
+ Q L R S + T S T+ QP G I D + V
Sbjct: 2361 LGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTLGANGVILDNQPIV 2412
>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
Length = 757
Score = 33.9 bits (76), Expect = 0.30
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)
Query: 67 EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
++TPL N T S P+ + +PS S+ +E+ E +T K + +
Sbjct: 461 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 503
Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
L++ I ++ DEE DG+S++A LE P
Sbjct: 504 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 539
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 33.9 bits (76), Expect = 0.30
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)
Query: 67 EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
++TPL N T S P+ + +PS S+ +E+ E +T K + +
Sbjct: 567 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 609
Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
L++ I ++ DEE DG+S++A LE P
Sbjct: 610 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 645
>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
Length = 951
Score = 33.9 bits (76), Expect = 0.30
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)
Query: 67 EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
++TPL N T S P+ + +PS S+ +E+ E +T K + +
Sbjct: 640 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 682
Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
L++ I ++ DEE DG+S++A LE P
Sbjct: 683 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 718
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 33.5 bits (75), Expect = 0.40
Identities = 17/79 (21%), Positives = 38/79 (48%)
Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
S SS D+ N+ D++ + + + S++ N + ++ S + NS+ S
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 162 NSTDTGTSGSATAAQPADN 180
NS+D+ S ++ + +D+
Sbjct: 958 NSSDSSNSSDSSDSNSSDS 976
Score = 33.1 bits (74), Expect = 0.52
Identities = 17/77 (22%), Positives = 37/77 (48%)
Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
S S D+ ++ D+++ + D S+S N + D + S + NS+ S NS
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 164 TDTGTSGSATAAQPADN 180
+D+ S ++ + +++
Sbjct: 807 SDSSDSSDSSDSDSSNS 823
Score = 32.3 bits (72), Expect = 0.88
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 96 DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
D ++ S S ++ N+ D++ + D S+S N + +D + S E
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS----DSSDSSNSSDSSDSSNSSDSSESS 927
Query: 156 NSASSQNSTDTGTSGSATAAQPADN 180
NS+ + NS+D+ S ++ + + N
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSN 952
Score = 32.3 bits (72), Expect = 0.88
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
S+S D+ N+ D++ + D S S + + +D + S + NS+ S NS
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS---DSSNSSDSSNS 965
Query: 164 TDTGTSGSATAAQPADNLLGDIDDLED 190
+D+ S S+ ++ +++ D D D
Sbjct: 966 SDSSDSNSSDSSDSSNS--SDSSDSSD 990
Score = 32.3 bits (72), Expect = 0.88
Identities = 18/72 (25%), Positives = 33/72 (45%)
Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
S S+S D+ N+ D++ + D S S + + +D S + NS+ S
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 162 NSTDTGTSGSAT 173
NS+D+ S ++
Sbjct: 1029 NSSDSSDSSDSS 1040
Score = 31.2 bits (69), Expect = 2.0
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
S S D+ N+ D+ + + S+S N + +D S S+ + NS+ S NS
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS-SDSSDSDSSNSSDSSNS 829
Query: 164 TDTG-TSGSATAAQPADNLLGDIDD 187
+D+ +S S+ ++ +D+ G D
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSD 854
Score = 30.8 bits (68), Expect = 2.6
Identities = 18/85 (21%), Positives = 41/85 (48%)
Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
S S+S D ++ D+++ + D S+S + + ++ S + NS+ S
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 162 NSTDTGTSGSATAAQPADNLLGDID 186
+S+D+ S S+ ++ +++ D D
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSD 727
Score = 30.4 bits (67), Expect = 3.4
Identities = 17/85 (20%), Positives = 39/85 (45%)
Query: 96 DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
D + + S S D+ N+ D++ + + S+S + +D S +
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 156 NSASSQNSTDTGTSGSATAAQPADN 180
NS+ S +S+D+ S S+ ++ +++
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNS 829
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/76 (23%), Positives = 34/76 (44%)
Query: 96 DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
D + S S D+ ++ D++ + D S+S + +E +D S +
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247
Query: 156 NSASSQNSTDTGTSGS 171
NS+ S +S+D+ S S
Sbjct: 1248 NSSDSSDSSDSSDSTS 1263
Score = 30.0 bits (66), Expect = 4.4
Identities = 16/72 (22%), Positives = 34/72 (47%)
Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
S SS + ++ ++ D+++ + D S+S + +D S + NS+ S
Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022
Query: 162 NSTDTGTSGSAT 173
NS+D+ S ++
Sbjct: 1023 NSSDSSNSSDSS 1034
Score = 29.6 bits (65), Expect = 5.7
Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
S SS ++ D+++ + D SES N + ++ S + +S+ S
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Query: 162 NSTD-TGTSGSATAAQPADNLLGDIDD 187
NS+D + +S S+ ++ +D+ D D
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSD 978
Score = 29.3 bits (64), Expect = 7.5
Identities = 16/78 (20%), Positives = 35/78 (44%)
Query: 96 DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
D + S S D+ ++ D+++ + D S+S + + +D S +
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 156 NSASSQNSTDTGTSGSAT 173
NS+ S +S+D+ S ++
Sbjct: 1092 NSSDSSDSSDSSDSSDSS 1109
Score = 29.3 bits (64), Expect = 7.5
Identities = 21/96 (21%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 96 DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
D ++ S S D+ ++ +++ E D S+S + + +D S +
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 156 NSASSQNSTDTG-TSGSATAAQPADNLLGDIDDLED 190
NS+ S +S+D+ +S S+ ++ +D+ D D D
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDS--SDSSDSSD 1212
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 23/116 (19%)
Query: 185 IDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKS 244
ID E+ ++P P +IIR + G+ G T + ++ + R K S
Sbjct: 489 IDVNENPYFAPNP-------KIIRQEEGLHAGTMLTTFT---AQDPDRYMQQNIRYTKLS 538
Query: 245 KTANYLISIDPVD--------LSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRG 292
AN+L IDPV+ L RE + +++N+ F D GI PM G G
Sbjct: 539 DPANWL-KIDPVNGQITTIAVLDRESPN----VKNNIYNATFLASDNGIPPMSGTG 589
>gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
Length = 995
Score = 32.7 bits (73), Expect = 0.68
Identities = 34/158 (21%), Positives = 67/158 (42%), Gaps = 16/158 (10%)
Query: 53 PEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDA 112
P +R + + ++ P V + P + DG V+ +E+++ + ED
Sbjct: 48 PRSRKQPPPKESKPKRMPRVKKNAPQIS------DGSEVVVVKEELNSSVAIADTALEDR 101
Query: 113 ENTVDT-----ASKPGLQERLQKHDI--SESVNFDEETDGISQSACLERPNSASSQNSTD 165
+N +DT +K + Q H + ++ + +EET S+++ LE +++S ST
Sbjct: 102 KNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEET---SKASNLEGESNSSETPSTS 158
Query: 166 TGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVR 203
T G+ + D+ L+ PQG V+
Sbjct: 159 TVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVK 196
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 32.3 bits (72), Expect = 0.88
Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 51 PNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEE 110
P+P R+ + + T P S++I H + PA+ PD +VS E
Sbjct: 963 PSPATRMHSGQHSTQAQSTGQGGLSAP-SSLICHSLCDPAS-FPPD---GATVSIKPEPE 1017
Query: 111 DAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
D E T GLQ+ + D++E + D +SQ A + R S S D G S
Sbjct: 1018 DREPNFATI---GLQD-ITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRS 1072
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 32.3 bits (72), Expect = 0.88
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 19/147 (12%)
Query: 2 EASRCRLSPSGDSVFHEEMMKMRQAK-LDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
EA R + ++ EE ++RQ + +QR E+ +RKKRLE M R RR
Sbjct: 560 EAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIM------KRTRRT 613
Query: 61 KPRASDEQTPLVNCHTPHSNVILHGIDGPAAV-LKPDEVHAPS----VSSSVVEEDAENT 115
+ A+D++T + ++ + G V P +AP V S V ++
Sbjct: 614 E--ATDKKT----SDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSK 667
Query: 116 VDTASKPGLQERLQKHDIS-ESVNFDE 141
V S P L+++ ++ +S ++ NF+E
Sbjct: 668 VTVESTPDLEKQPNENGVSVQNENFEE 694
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 32.0 bits (71), Expect = 1.2
Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 32/210 (15%)
Query: 15 VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLR 58
+ ++++ + L+Y+R LE++++ +RL+ + Q P + L
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519
Query: 59 RAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSS 106
K S + P PH ++ GP A+ VH A +V+S
Sbjct: 520 HYKEGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSH 576
Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
VE +N+ T+ P L R++K D S + +E+ + + +NS
Sbjct: 577 RVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGN 636
Query: 167 GTS-GSATAAQPADNLLGDIDDLEDFVYSP 195
G++ G +QP D+ E + SP
Sbjct: 637 GSALGPRLGSQPIRASNPDLRRTEPILESP 666
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 32.0 bits (71), Expect = 1.2
Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 32/210 (15%)
Query: 15 VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLR 58
+ ++++ + L+Y+R LE++++ +RL+ + Q P + L
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519
Query: 59 RAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSS 106
K S + P PH ++ GP A+ VH A +V+S
Sbjct: 520 HYKEGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSH 576
Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
VE +N+ T+ P L R++K D S + +E+ + + +NS
Sbjct: 577 RVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGN 636
Query: 167 GTS-GSATAAQPADNLLGDIDDLEDFVYSP 195
G++ G +QP D+ E + SP
Sbjct: 637 GSALGPRLGSQPIRASNPDLRRTEPILESP 666
>gi|9966761 choroideremia isoform a [Homo sapiens]
Length = 653
Score = 31.2 bits (69), Expect = 2.0
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Query: 98 VHAPSVSSSVVEEDAENTVDTASKPGLQ-----ERLQKHDISESVNFD-EETDGISQSAC 151
VH SS ED E+ V P + E+++K I ++ F+ ++ IS+S
Sbjct: 506 VHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQVEKPRILWALYFNMRDSSDISRSCY 565
Query: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195
+ P++ + D G G+ A + A+ L +I EDF P
Sbjct: 566 NDLPSNVYVCSGPDCGL-GNDNAVKQAETLFQEICPNEDFCPPP 608
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 31.2 bits (69), Expect = 2.0
Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 29/193 (15%)
Query: 19 EMMKMRQAKLDYQRLLLEKRQ---RKKRLEPFMVQP-NPEARLRRAKPRASDEQTPLVNC 74
E +K+ K+D R + +Q RKK L P + P NP + +KP E T +N
Sbjct: 401 EGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKP----EVTVRLNV 456
Query: 75 H-----TPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE--R 127
H T ++ A ++ ++ + SS E N S+ G++ R
Sbjct: 457 HKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSR 516
Query: 128 LQKHDI------------SESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAA 175
LQ D SE + D E + + + E+ ++++ + T+GS A
Sbjct: 517 LQADDFLQDYTLLINILHSEDLGKDVEFEVVGDAP--EKVGPKQAEDAAKSITNGSDDGA 574
Query: 176 QPADNLLGDIDDL 188
QP+ + + DD+
Sbjct: 575 QPSTSTAQEQDDV 587
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 30.8 bits (68), Expect = 2.6
Identities = 36/146 (24%), Positives = 56/146 (38%), Gaps = 7/146 (4%)
Query: 49 VQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH--APSVSSS 106
V PE +R A+ +Q P+ N P + + D P + PD++ + SV +
Sbjct: 847 VDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFS--HPDKLKRMSKSVPAF 904
Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
+ +E + DTAS+ Q K S N + S S+ S S S D
Sbjct: 905 LQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSV---SGSVMSVYSGDF 961
Query: 167 GTSGSATAAQPADNLLGDIDDLEDFV 192
G Q A + + +L FV
Sbjct: 962 GNLEVKGNIQFAIEYVESLKELHVFV 987
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 30.8 bits (68), Expect = 2.6
Identities = 45/207 (21%), Positives = 80/207 (38%), Gaps = 32/207 (15%)
Query: 18 EEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLRRAK 61
EE + + + +Y+R LE++++ +RL+ + Q P + L K
Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYK 493
Query: 62 PRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSSVVE 109
S + P PH ++ GP A+ VH A +V+S VE
Sbjct: 494 EGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSHRVE 550
Query: 110 EDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
+N+ T+ P L R++K D S + +E+ + + +NS G++
Sbjct: 551 MPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSA 610
Query: 170 -GSATAAQPADNLLGDIDDLEDFVYSP 195
G +QP D+ E + SP
Sbjct: 611 LGPRLGSQPIRASNPDLRRTEPILESP 637
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 30.8 bits (68), Expect = 2.6
Identities = 45/207 (21%), Positives = 80/207 (38%), Gaps = 32/207 (15%)
Query: 18 EEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLRRAK 61
EE + + + +Y+R LE++++ +RL+ + Q P + L K
Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYK 493
Query: 62 PRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSSVVE 109
S + P PH ++ GP A+ VH A +V+S VE
Sbjct: 494 EGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSHRVE 550
Query: 110 EDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
+N+ T+ P L R++K D S + +E+ + + +NS G++
Sbjct: 551 MPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSA 610
Query: 170 -GSATAAQPADNLLGDIDDLEDFVYSP 195
G +QP D+ E + SP
Sbjct: 611 LGPRLGSQPIRASNPDLRRTEPILESP 637
>gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
Length = 678
Score = 30.8 bits (68), Expect = 2.6
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 13/63 (20%)
Query: 264 SYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSV 323
+Y+ ++ SN+ GTKF + GL AA L A+ Y+T++L + PR+M++
Sbjct: 594 NYLAQVTSNIWGTKFKIV----------GL--AAFLPTNLGAVIYKTSLLHLQ-PRQMTI 640
Query: 324 IIP 326
+P
Sbjct: 641 YLP 643
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 30.8 bits (68), Expect = 2.6
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 44 LEPFMVQPNPEARLRRAKPRASDEQTP-----LVNCHTPH------SNVILHGIDGPAAV 92
L P QPNP + KP AS E TP L N PH +V+ PA +
Sbjct: 862 LGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKI 921
Query: 93 LKPDEVHAPSVSSSV 107
L + +S +V
Sbjct: 922 LNCTNIECLQISCAV 936
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 12/110 (10%)
Query: 46 PFMVQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGID-------GPAAVLKPDEV 98
P ++Q P+ P+ + QTP+V PH+ ++L P V+KP +
Sbjct: 740 PLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVL 799
Query: 99 HAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISE-----SVNFDEET 143
S+V + A + +PG DI++ VN EE+
Sbjct: 800 PGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEES 849
>gi|37595553 ring finger protein 111 [Homo sapiens]
Length = 986
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 7/95 (7%)
Query: 90 AAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQS 149
+ V++P +A V V+ED V T S R++ S S+N S+
Sbjct: 369 STVIQPLRQNAAEVVDLTVDEDEPTVVPTTSA-----RMESQATSASIN--NSNPSTSEQ 421
Query: 150 ACLERPNSASSQNSTDTGTSGSATAAQPADNLLGD 184
A SSQ ST + TS + T+ +GD
Sbjct: 422 ASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGD 456
>gi|149773449 zinc finger protein 862 [Homo sapiens]
Length = 1169
Score = 30.4 bits (67), Expect = 3.4
Identities = 43/163 (26%), Positives = 64/163 (39%), Gaps = 14/163 (8%)
Query: 20 MMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARL-RRAKPRASDEQTPLVNCHTPH 78
M+ RQ +L Y+ ++ + L P +P+ ++L RRA P D P P
Sbjct: 349 MLDKRQKEL-YRDVMRMNYELLASLGPAAAKPDLISKLERRAAPWIKDPNGPKWGKGRPP 407
Query: 79 SN---VILHGIDGPAAVL-------KPDEVHAPSVSSSVVEE-DAENTVDTASKPGLQER 127
N V + D A+ P E A SSS+ EE D + +P +R
Sbjct: 408 GNKKMVAVREADTQASAADSALLPGSPVEARASCCSSSICEEGDGPRRIKRTYRPRSIQR 467
Query: 128 LQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSG 170
V +ET + SAC+ERPN + G +G
Sbjct: 468 SWFGQFPWLVIDPKETK-LFCSACIERPNLHDKSSRLVRGYTG 509
>gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]
Length = 656
Score = 30.4 bits (67), Expect = 3.4
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 98 VHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISE-----SVNFD-EETDGISQSAC 151
VH SS ED E+ V P + + + ++++ ++ F+ ++ GIS+S+
Sbjct: 508 VHLTCSSSKTAREDLESVVKKLFTPYTETEINEEELTKPRLLWALYFNMRDSSGISRSSY 567
Query: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195
P++ + D G G+ A + A+ L +I E+F P
Sbjct: 568 NGLPSNVYVCSGPDCGL-GNEHAVKQAETLFQEIFPTEEFCPPP 610
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,928,783
Number of Sequences: 37866
Number of extensions: 760414
Number of successful extensions: 2633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2578
Number of HSP's gapped (non-prelim): 73
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.