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Search of human proteins with 21450749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 1073 0.0
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 1049 0.0
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 508 e-144
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 507 e-144
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 418 e-117
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 412 e-115
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 390 e-108
gi|33563374 carboxylesterase 3 [Homo sapiens] 374 e-103
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 366 e-101
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 365 e-101
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 365 e-101
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 256 3e-68
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 253 3e-67
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 253 4e-67
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 239 4e-63
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 239 4e-63
gi|51593088 neuroligin 3 [Homo sapiens] 239 4e-63
gi|7662470 neuroligin 1 [Homo sapiens] 238 1e-62
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 237 2e-62
gi|30840978 neuroligin 2 [Homo sapiens] 230 2e-60
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 200 3e-51
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 172 9e-43
gi|55770862 thyroglobulin [Homo sapiens] 154 2e-37
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 40 0.005
gi|16933540 fibroblast activation protein, alpha subunit [Homo s... 36 0.075
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 34 0.37
gi|239757732 PREDICTED: similar to KIAA1654 protein [Homo sapiens] 33 0.64
gi|118402590 myosin XV [Homo sapiens] 30 5.4
gi|167736355 mucin 4 isoform a [Homo sapiens] 30 5.4
gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo sa... 30 7.1
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 1073 bits (2774), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV 60
MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV
Sbjct: 1 MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV 60
Query: 61 PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED 120
PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED
Sbjct: 61 PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED 120
Query: 121 CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF
Sbjct: 121 CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
Query: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM
Sbjct: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
Query: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL
Sbjct: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
Query: 301 LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS
Sbjct: 301 LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 361 GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA 420
GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA
Sbjct: 361 GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA 420
Query: 421 RYHREGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQR 480
RYHREGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQR
Sbjct: 421 RYHREGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQR 480
Query: 481 LKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP 525
LKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP
Sbjct: 481 LKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP 525
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 1049 bits (2713), Expect = 0.0
Identities = 525/575 (91%), Positives = 525/575 (91%), Gaps = 50/575 (8%)
Query: 1 MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV 60
MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV
Sbjct: 1 MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGV 60
Query: 61 PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED 120
PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED
Sbjct: 61 PFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSED 120
Query: 121 CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF
Sbjct: 121 CLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
Query: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM
Sbjct: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
Query: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL
Sbjct: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
Query: 301 LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS
Sbjct: 301 LTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 361 GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA 420
GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA
Sbjct: 361 GSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITA 420
Query: 421 RYHR--------------------------------------------------EGATEE 430
RYHR EGATEE
Sbjct: 421 RYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEE 480
Query: 431 EKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWT 490
EKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWT
Sbjct: 481 EKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWT 540
Query: 491 STIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP 525
STIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP
Sbjct: 541 STIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP 575
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 508 bits (1307), Expect = e-144
Identities = 257/291 (88%), Positives = 269/291 (92%)
Query: 146 GGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 205
GGAF+TGSASIFDGS+LAAYED+LVV+VQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 206 VQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDY 265
VQKNIEFFGGDPSSVTIFGES GAISVSSL+LSPMA+GLFHKA+MESGVAII YL+AHDY
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 266 EKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLD 325
EKSEDLQVVA FCG NASDSEA LRCLRTK SKELLTLSQKTK+FT+VVDGAFFPNEPLD
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFTQVVDGAFFPNEPLD 199
Query: 326 LLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLV 385
LLSQKAFKAIPSIIGVNN ECGF LPMKEAPEILSGSNKSLAL L QNILHI P YLHLV
Sbjct: 200 LLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALCLTQNILHILPNYLHLV 259
Query: 386 ANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGATEEEKLLSR 436
A EYFHDKHSLTEIRDSLLDLLGDVFFV+P LITARYHR + LL R
Sbjct: 260 AGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYHRGQIPQGRYLLLR 310
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 507 bits (1306), Expect = e-144
Identities = 257/291 (88%), Positives = 269/291 (92%)
Query: 146 GGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 205
GGAF+TGSASIFDGS+LAAYED+LVV+VQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 206 VQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDY 265
VQKNIEFFGGDPSSVTIFGES GAISVSSLILSPMA+GLFHKA+MESGVAII YL+AHDY
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 266 EKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLD 325
EKSEDLQVVA FCG NASDSEA LRCLRTK SKELLTLSQKTK+FT+VVDGAFFPNEPLD
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFTQVVDGAFFPNEPLD 199
Query: 326 LLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLV 385
LLSQKAFKAIPSIIGVNN ECGF LPMKEAPEILSGSNKSLAL L QNILHI P YLHLV
Sbjct: 200 LLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALCLTQNILHILPNYLHLV 259
Query: 386 ANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGATEEEKLLSR 436
A EYFHDKHSLTEIRDSLLDLLGDVFFV+P LITA+YHR + LL R
Sbjct: 260 AGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYHRGQIPQGRYLLLR 310
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 418 bits (1075), Expect = e-117
Identities = 224/509 (44%), Positives = 304/509 (59%), Gaps = 44/509 (8%)
Query: 24 KGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDN 83
+G + P R T G + G V V G+ V FLG+PFA PPLG LRF P+P W
Sbjct: 89 QGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSG 148
Query: 84 LREATSYPNLCLQN-----SEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKL 138
+R+ T++P +CLQ+ SE+L + +P +SEDCLYL+IY PAH+ GS L
Sbjct: 149 VRDGTTHPAMCLQDLTAVESEFL----SQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNL 204
Query: 139 PVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198
PV+VW GGA G AS++DGS LAA E+V+VV++QYRLG+ GFF+T D+HA GNW + D
Sbjct: 205 PVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264
Query: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP 258
QVAAL WVQ+NI FGG+P VTIFGESAG SVSSL++SP+++GLFH AIMESGVA++P
Sbjct: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLP 324
Query: 259 YLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAF 318
L A + VVA+ + DSEAL+ CLR K +E+L +++ K VVDG F
Sbjct: 325 GLIASSADVIS--TVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVF 382
Query: 319 FPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQNI 374
P P +LL+ F+ +PSI+GVNN+E G+L+P + + + + AL + +
Sbjct: 383 LPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL 442
Query: 375 LHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGA------- 427
L +PP + L+ EY D ++ +++ D FV+PAL A + A
Sbjct: 443 LMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEF 502
Query: 428 ----------------------TEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLT 465
TEEE+ LSRKMMKYWA FAR GNPNG L WP ++
Sbjct: 503 QHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQE 562
Query: 466 EQYLQLDLNMSLGQRLKEPRVDFWTSTIP 494
EQYLQL+L ++G+ LK R+ FW +P
Sbjct: 563 EQYLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 412 bits (1059), Expect = e-115
Identities = 224/525 (42%), Positives = 304/525 (57%), Gaps = 60/525 (11%)
Query: 24 KGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDN 83
+G + P R T G + G V V G+ V FLG+PFA PPLG LRF P+P W
Sbjct: 89 QGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSG 148
Query: 84 LREATSYPNLCLQN-----SEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKL 138
+R+ T++P +CLQ+ SE+L + +P +SEDCLYL+IY PAH+ GS L
Sbjct: 149 VRDGTTHPAMCLQDLTAVESEFL----SQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNL 204
Query: 139 PVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198
PV+VW GGA G AS++DGS LAA E+V+VV++QYRLG+ GFF+T D+HA GNW + D
Sbjct: 205 PVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264
Query: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP 258
QVAAL WVQ+NI FGG+P VTIFGESAG SVSSL++SP+++GLFH AIMESGVA++P
Sbjct: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLP 324
Query: 259 YLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAF 318
L A + VVA+ + DSEAL+ CLR K +E+L +++ K VVDG F
Sbjct: 325 GLIASSADVIS--TVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVF 382
Query: 319 FPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQNI 374
P P +LL+ F+ +PSI+GVNN+E G+L+P + + + + AL + +
Sbjct: 383 LPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTL 442
Query: 375 LHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGA------- 427
L +PP + L+ EY D ++ +++ D FV+PAL A + A
Sbjct: 443 LMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEF 502
Query: 428 --------------------------------------TEEEKLLSRKMMKYWATFARTG 449
TEEE+ LSRKMMKYWA FAR G
Sbjct: 503 QHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNG 562
Query: 450 NPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 494
NPNG L WP ++ EQYLQL+L ++G+ LK R+ FW +P
Sbjct: 563 NPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALP 607
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 390 bits (1001), Expect = e-108
Identities = 214/482 (44%), Positives = 290/482 (60%), Gaps = 51/482 (10%)
Query: 31 PQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSY 90
PQ T+ G +QGKQ+ V P+ VFLGVPF+ PPLG LRF P+P PW +R+AT+Y
Sbjct: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84
Query: 91 PNLCLQNSEWLLLDQHM-LKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAF 149
P CLQ S L ++ + Y SEDCLYLN+YAPA A +LPV+VWFPGGAF
Sbjct: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144
Query: 150 KTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKN 209
G+AS ++GS LAA E V++V +Q+RLGIFGF +T D HA GNW DQ+AAL WVQ+N
Sbjct: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204
Query: 210 IEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSE 269
I FGGDP +VT+FG+SAGA+S+S L++SP+A GLFH+AI +SG A+ + S
Sbjct: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRL-----FITSN 259
Query: 270 DLQV---VAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK---------------SFT 311
L+V VAH G N + ++ L+ CLR +++ +S K + S +
Sbjct: 260 PLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMS 319
Query: 312 RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLI 371
VVDG P++PL LL+Q ++P ++GVNN E +LLP
Sbjct: 320 PVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-------------------- 359
Query: 372 QNILHIPPQYLHLVANEYFH--DKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGATE 429
+I + + LV EY ++H +R+ ++D++ D FV L TA YHR +
Sbjct: 360 ---YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLSMG 416
Query: 430 EEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFW 489
+EK LS +MMKYWA FARTGNPN +L WP YN E+YLQLD +G +LKE ++ FW
Sbjct: 417 KEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFW 476
Query: 490 TS 491
S
Sbjct: 477 MS 478
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 374 bits (960), Expect = e-103
Identities = 212/533 (39%), Positives = 299/533 (56%), Gaps = 63/533 (11%)
Query: 21 APTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASP 80
A GP P+ +T LG ++G+QV V G+ VNVFLG+PFA PPLG RF+ P PA P
Sbjct: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83
Query: 81 WDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPV 140
W+ +R+A++ P +CLQ+ E + + +L F VSEDCL LN+Y+PA GS PV
Sbjct: 84 WEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPV 143
Query: 141 LVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQV 200
+VW GGA TG+A+ +DGSALAAY DV+VV VQYRLG+ GFF+T D+HAPGN F D V
Sbjct: 144 MVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVV 203
Query: 201 AALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP-Y 259
AAL WVQ+NI FGGD + VT+FG SAG +S L+LSP+A GLFH+AI +SGV P
Sbjct: 204 AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGI 263
Query: 260 LEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKS--FTRVVDGA 317
+++H + + Q +A+ ++S +++CL+ K +EL+ LS+K K+ + VDG
Sbjct: 264 IDSHPWPLA---QKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLKNTIYPLTVDGT 319
Query: 318 FFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLP----MKEAPEILSGSNKSLALHLIQN 373
FP P +LL +K F ++P ++GVNNHE +L+P + + E +S + +
Sbjct: 320 VFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLT 379
Query: 374 ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHREG------- 426
L +PP+ + V +EY + + +GDVF VP + +RY R+
Sbjct: 380 SLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFY 439
Query: 427 ---------------------------------------------ATEEEKLLSRKMMKY 441
ATEEEK LS MM
Sbjct: 440 EFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQ 499
Query: 442 WATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIP 494
W FARTG+PN L WP +N EQYL+++ GQ+ +E + FW+ T+P
Sbjct: 500 WTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 366 bits (940), Expect = e-101
Identities = 216/539 (40%), Positives = 294/539 (54%), Gaps = 70/539 (12%)
Query: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
Query: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
Query: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
Query: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
Query: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
V+DG P +L +++ F +P ++G+N E G+L+PM + +
Sbjct: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSE 369
Query: 361 GS-NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPA 416
G ++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP+
Sbjct: 370 GQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPS 429
Query: 417 LITARYHR--------------------------------------------EGATEEEK 432
+I AR HR EGA+EEE
Sbjct: 430 VIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEI 489
Query: 433 LLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491
LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+
Sbjct: 490 RLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 548
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 365 bits (937), Expect = e-101
Identities = 217/540 (40%), Positives = 294/540 (54%), Gaps = 71/540 (13%)
Query: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
+A G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 14 SAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 73
Query: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 74 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 133
Query: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193
Query: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253
Query: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 254 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 310
Query: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
V+DG P +L +++ F +P ++G+N E G+L+PM+ LS
Sbjct: 311 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 370
Query: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415
++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP
Sbjct: 371 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 430
Query: 416 ALITARYHR--------------------------------------------EGATEEE 431
++I AR HR EGA+EEE
Sbjct: 431 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEE 490
Query: 432 KLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491
LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+
Sbjct: 491 IRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 550
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 365 bits (937), Expect = e-101
Identities = 217/540 (40%), Positives = 294/540 (54%), Gaps = 71/540 (13%)
Query: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
Query: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
Query: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
Query: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
Query: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
V+DG P +L +++ F +P ++G+N E G+L+PM+ LS
Sbjct: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 369
Query: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415
++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP
Sbjct: 370 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 429
Query: 416 ALITARYHR--------------------------------------------EGATEEE 431
++I AR HR EGA+EEE
Sbjct: 430 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEE 489
Query: 432 KLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491
LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+
Sbjct: 490 IRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 549
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 256 bits (655), Expect = 3e-68
Identities = 189/571 (33%), Positives = 283/571 (49%), Gaps = 88/571 (15%)
Query: 11 ILIWAIWVLAAPTKGPSAEGPQR-----NTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAP 65
+L+ +W+L G AEG + R G ++G ++ G PV + FLG+PFA P
Sbjct: 17 LLLLLLWLLGG---GVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV--SAFLGIPFAEP 71
Query: 66 PLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLN 125
P+G RF P+P PW + +AT++ ++C Q + L ++ P +SEDCLYLN
Sbjct: 72 PMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLN 131
Query: 126 IYAPAHADTGSKLPVLVWFPGGAFKTGSAS--IFDGSALAAYEDVLVVVVQYRLGIFGFF 183
++ P T S PVLVW GG F +G++S ++DG L E ++V + YR+G FGF
Sbjct: 132 VWTPYPRPT-SPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFL 190
Query: 184 TT-WDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAK 242
+ APGN DQ AL WVQ+N+ FGGDP+SVT+FGESAGA SV +LSP ++
Sbjct: 191 ALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSR 250
Query: 243 GLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFC-----GNNASDSEALLRCLRTKPS 297
GLFH+A+++SG P+ E +AH G +D+E L+ CLRT+P+
Sbjct: 251 GLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTE-LVACLRTRPA 309
Query: 298 KELL-----TLSQKTK---SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349
+ L+ L Q++ SF VVDG F + P L++ F + ++GV E +
Sbjct: 310 QVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYF 369
Query: 350 LPMKEAPEILSGSNKSL--ALHLIQNILHIPPQYLHLVA-------NEYFHDKHSLTEIR 400
L + AP S N+SL + + PQ L A ++ H + +R
Sbjct: 370 L-VYGAPG-FSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDP-ARLR 426
Query: 401 DSLLDLLGDVFFVVP-ALITARYHREGA-------------------------------- 427
++L D++GD V P A + R +GA
Sbjct: 427 EALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIF 486
Query: 428 ----------TEEEKLLSRKMMKYWATFARTGNPN---GNDLSLWPAYNL-TEQYLQLDL 473
T EEK+ ++++M+YWA FARTG+PN WP Y +QY+ LDL
Sbjct: 487 GIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDL 546
Query: 474 N-MSLGQRLKEPRVDFWTSTIPLILSASDML 503
+ + + L+ FW +P +LSA+D L
Sbjct: 547 RPLEVRRGLRAQACAFWNRFLPKLLSATDTL 577
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 253 bits (646), Expect = 3e-67
Identities = 187/568 (32%), Positives = 281/568 (49%), Gaps = 88/568 (15%)
Query: 11 ILIWAIWVLAAPTKGPSAEGPQR-----NTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAP 65
+L+ +W+L G AEG + R G ++G ++ G PV + FLG+PFA P
Sbjct: 17 LLLLLLWLLGG---GVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV--SAFLGIPFAEP 71
Query: 66 PLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLN 125
P+G RF P+P PW + +AT++ ++C Q + L ++ P +SEDCLYLN
Sbjct: 72 PMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLN 131
Query: 126 IYAPAHADTGSKLPVLVWFPGGAFKTGSAS--IFDGSALAAYEDVLVVVVQYRLGIFGFF 183
++ P T S PVLVW GG F +G++S ++DG L E ++V + YR+G FGF
Sbjct: 132 VWTPYPRPT-SPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFL 190
Query: 184 TT-WDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAK 242
+ APGN DQ AL WVQ+N+ FGGDP+SVT+FGESAGA SV +LSP ++
Sbjct: 191 ALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSR 250
Query: 243 GLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFC-----GNNASDSEALLRCLRTKPS 297
GLFH+A+++SG P+ E +AH G +D+E L+ CLRT+P+
Sbjct: 251 GLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTE-LVACLRTRPA 309
Query: 298 KELL-----TLSQKTK---SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFL 349
+ L+ L Q++ SF VVDG F + P L++ F + ++GV E +
Sbjct: 310 QVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYF 369
Query: 350 LPMKEAPEILSGSNKSL--ALHLIQNILHIPPQYLHLVA-------NEYFHDKHSLTEIR 400
L + AP S N+SL + + PQ L A ++ H + +R
Sbjct: 370 L-VYGAPG-FSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDP-ARLR 426
Query: 401 DSLLDLLGDVFFVVP-ALITARYHREGA-------------------------------- 427
++L D++GD V P A + R +GA
Sbjct: 427 EALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIF 486
Query: 428 ----------TEEEKLLSRKMMKYWATFARTGNPN---GNDLSLWPAYNL-TEQYLQLDL 473
T EEK+ ++++M+YWA FARTG+PN WP Y +QY+ LDL
Sbjct: 487 GIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDL 546
Query: 474 N-MSLGQRLKEPRVDFWTSTIPLILSAS 500
+ + + L+ FW +P +LSA+
Sbjct: 547 RPLEVRRGLRAQACAFWNRFLPKLLSAT 574
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 253 bits (645), Expect = 4e-67
Identities = 180/528 (34%), Positives = 256/528 (48%), Gaps = 70/528 (13%)
Query: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
T+ G ++G +TV G V FLG+P+A PPLG LRF PQ + W ++ AT Y N C
Sbjct: 36 TKNGKVRGMNLTVFGGTV--TAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSC 93
Query: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSA 154
QN + H ++ P +SEDCLYLN++ PA + VL+W GG F+TG++
Sbjct: 94 CQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNA--TVLIWIYGGGFQTGTS 151
Query: 155 S--IFDGSALAAYEDVLVVVVQYRLGIFGFFT-TWDQHAPGNWAFKDQVAALSWVQKNIE 211
S ++DG LA E V+VV + YR+G GF + APGN DQ AL WVQKNI
Sbjct: 152 SLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIA 211
Query: 212 FFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDL 271
FGG+P SVT+FGESAGA SVS +LSP + LF +AI++SG P+ YE
Sbjct: 212 AFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRT 271
Query: 272 QVVAHFCGNNASDSEALLRCLRTKPSKELLTL--------SQKTKSFTRVVDGAFFPNEP 323
+A G + + +++CLR K +E+L + + +F VDG F + P
Sbjct: 272 LNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMP 331
Query: 324 LDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLH 383
LL FK ++GVN E G + AP +N + Q L I +
Sbjct: 332 DILLELGQFKKTQILVGVNKDE-GTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVS 390
Query: 384 LVANE--YFH-----DKHSLTEIRDSLLDLLGDVFFVVPAL-ITARY------------- 422
E FH D R++L D++GD F+ PAL T ++
Sbjct: 391 EFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFE 450
Query: 423 -----------------------------HREGATEEEKLLSRKMMKYWATFARTGNPN- 452
R+ T+ E++LSR ++K WA FA+ GNPN
Sbjct: 451 HRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNE 510
Query: 453 -GNDLSLWPAYNLTEQ-YLQLDLNMS-LGQRLKEPRVDFWTSTIPLIL 497
N+ + WP + TEQ YL L+ + + +L+ + FWTS P +L
Sbjct: 511 TQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKVL 558
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 239 bits (610), Expect = 4e-63
Identities = 174/572 (30%), Positives = 274/572 (47%), Gaps = 96/572 (16%)
Query: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSL 70
+W+ A K A+ P NT G I+G + + + PV +LGVP+A+PP G
Sbjct: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
Query: 71 RFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDC 121
RF P+P S W +R T + +C Q+ + L ML + + +EDC
Sbjct: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
Query: 122 LYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLG 178
LYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + YRLG
Sbjct: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
Query: 179 IFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILS 238
I GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L LS
Sbjct: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
Query: 239 PMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSK 298
++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CLR K K
Sbjct: 267 HYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
Query: 299 ELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMK 353
EL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
Query: 354 EAPEILSGSNKSLAL-HLIQNILHIPP------QYLHLVANEYFHDKHSLTEIRDSLLDL 406
+ + ++ ++ ++ + + N+ P + + + ++ DK + R +L+ L
Sbjct: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW-ADKENPETRRKTLVAL 443
Query: 407 LGDVFFVVPALITARYHRE----------------------------------------G 426
D +V PA+ TA H + G
Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503
Query: 427 ATE--------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYN 463
TE + +LS +M YW FA+TG+PN + W YN
Sbjct: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYN 563
Query: 464 LTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 494
+Q YL + L + + +V FW +P
Sbjct: 564 PKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 239 bits (610), Expect = 4e-63
Identities = 174/572 (30%), Positives = 274/572 (47%), Gaps = 96/572 (16%)
Query: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSL 70
+W+ A K A+ P NT G I+G + + + PV +LGVP+A+PP G
Sbjct: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
Query: 71 RFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDC 121
RF P+P S W +R T + +C Q+ + L ML + + +EDC
Sbjct: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
Query: 122 LYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLG 178
LYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + YRLG
Sbjct: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
Query: 179 IFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILS 238
I GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L LS
Sbjct: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
Query: 239 PMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSK 298
++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CLR K K
Sbjct: 267 HYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
Query: 299 ELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMK 353
EL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
Query: 354 EAPEILSGSNKSLAL-HLIQNILHIPP------QYLHLVANEYFHDKHSLTEIRDSLLDL 406
+ + ++ ++ ++ + + N+ P + + + ++ DK + R +L+ L
Sbjct: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW-ADKENPETRRKTLVAL 443
Query: 407 LGDVFFVVPALITARYHRE----------------------------------------G 426
D +V PA+ TA H + G
Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503
Query: 427 ATE--------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYN 463
TE + +LS +M YW FA+TG+PN + W YN
Sbjct: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYN 563
Query: 464 LTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 494
+Q YL + L + + +V FW +P
Sbjct: 564 PKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 239 bits (610), Expect = 4e-63
Identities = 171/606 (28%), Positives = 286/606 (47%), Gaps = 115/606 (18%)
Query: 9 GQILIWAIWVLAAPTKGPS-AEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPP 66
G+ L +W L+ + + A P NT G ++G +V + + PV+ +LGVP+AAPP
Sbjct: 19 GRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPP 78
Query: 67 LGSLRFTNPQPASPWDNLREATSYPNLCLQNSE----------WLLLDQHMLKVHYPKFG 116
+G RF P+P W +R AT +P +C QN W + ++ + +
Sbjct: 79 IGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQE-- 136
Query: 117 VSEDCLYLNIYAPAHADTGSKL----------------------PVLVWFPGGAFKTGSA 154
+EDCLYLN+Y P +G+K PV+V+ GG++ G+
Sbjct: 137 PNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTG 196
Query: 155 SIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFG 214
++ DGS LA+Y +V+V+ + YR+G+ GF +T DQ A GN+ DQ+ AL WV +NI FFG
Sbjct: 197 NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 256
Query: 215 GDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVV 274
GDP +T+FG GA VS L LS ++GLF +AI++SG A+ + A +Y+ + ++
Sbjct: 257 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW--AVNYQPVKYTSLL 314
Query: 275 AHFCGNNASDSEALLRCLRTKPSKEL----LTLSQKTKSFTRVVDGAFFPNEPLDLLSQK 330
A G N D+ ++ CLR K +KEL + ++ +F V+DG P++P L+ Q
Sbjct: 315 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG 374
Query: 331 AFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLAL-HLIQNILHIPP------QYL 382
F ++GVN E F+ + + + +SG++ ++ + + N+ P + +
Sbjct: 375 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI 434
Query: 383 HLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-REGA-------------- 427
+ ++ D+ + R +L+ L D +V P+++TA H R G+
Sbjct: 435 KFMYTDW-ADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSL 493
Query: 428 ---------------------------------TEEEKLLSRKMMKYWATFARTGNPNGN 454
++ + +LS +M YW FA+TG+PN
Sbjct: 494 MKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKP 553
Query: 455 ---------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIPLILS 498
+ W YN +Q YL + L + + +V FW +P + +
Sbjct: 554 VPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN 613
Query: 499 ASDMLH 504
DM H
Sbjct: 614 LHDMFH 619
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 238 bits (607), Expect = 1e-62
Identities = 169/546 (30%), Positives = 260/546 (47%), Gaps = 98/546 (17%)
Query: 53 PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHY 112
PV FLGVP+AAPP G RF P+P SPW ++R AT + +C QN L + ML V +
Sbjct: 76 PVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWF 135
Query: 113 PKF---------GVSEDCLYLNIYAPAH---ADTGSKLPVLVWFPGGAFKTGSASIFDGS 160
SEDCLYLNIY P D+G PV+V+ GG++ G+ +++DGS
Sbjct: 136 TNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS 195
Query: 161 ALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSV 220
LA+Y +V+V+ V YRLG+ GF +T DQ A GN+ D + AL W +NI FFGGDP +
Sbjct: 196 VLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRI 255
Query: 221 TIFGESAGAISVSSLILSPMA---------KGLFHKAIMESGVAIIPYLEAHDYEKSEDL 271
T+FG AG V+ L LS + KGLF +AI +SG A+ + A ++ ++
Sbjct: 256 TVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSW--AVSFQPAKYA 313
Query: 272 QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK----SFTRVVDGAFFPNEPLDLL 327
+++A G N SD+ L+ CL+ KP KEL+ + +F V+DG P++P L+
Sbjct: 314 RMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILM 373
Query: 328 SQKAFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVA 386
Q F ++GVN E F+ + ++ + +S S+ A+ + L+ P+ ++
Sbjct: 374 EQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLR 433
Query: 387 NEY------FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRE--------------- 425
+ D+H+ R +LL L D +V PA+ TA H
Sbjct: 434 ETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQ 493
Query: 426 -------------------------GATE--------EEKLLSRKMMKYWATFARTGNPN 452
G TE + +LS +M YW FA+TG+PN
Sbjct: 494 TDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN 553
Query: 453 GN---------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIPLI 496
+ W Y+ +Q YL + L + + + +V+ W +P +
Sbjct: 554 QPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHL 613
Query: 497 LSASDM 502
+ +D+
Sbjct: 614 HNLNDI 619
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 237 bits (605), Expect = 2e-62
Identities = 176/573 (30%), Positives = 275/573 (47%), Gaps = 98/573 (17%)
Query: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV--PVNVFLGVPFAAPPLGS 69
+W+ A K A+ P NT G IQG + T L S + PV +LGVP+A+PP G
Sbjct: 27 LWITALAIKFTLIDSQAQYPVVNTNYGKIQGLR-TPLPSEILGPVEQYLGVPYASPPTGE 85
Query: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSED 120
RF P+ S W +R AT + +C Q+ + L ML + + +ED
Sbjct: 86 RRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNED 145
Query: 121 CLYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRL 177
CLYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + RL
Sbjct: 146 CLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRL 205
Query: 178 GIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLIL 237
GI GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L L
Sbjct: 206 GILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTL 265
Query: 238 SPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPS 297
S ++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CL+ K
Sbjct: 266 SHYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNY 323
Query: 298 KELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPM 352
KEL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 324 KELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGI 383
Query: 353 KEAPEILSGSNKSLAL-HLIQNILHIPP------QYLHLVANEYFHDKHSLTEIRDSLLD 405
+ + ++ ++ ++ + + N+ P + + + ++ DK + R +L+
Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW-ADKENPETRRKTLVA 442
Query: 406 LLGDVFFVVPALITARYHRE---------------------------------------- 425
L D +V PA+ TA H +
Sbjct: 443 LFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMI 502
Query: 426 GATE--------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAY 462
G TE + +LS +M YW FA+TG+PN + W Y
Sbjct: 503 GPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKY 562
Query: 463 NLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 494
N +Q YL + L + + +V FW +P
Sbjct: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 230 bits (587), Expect = 2e-60
Identities = 181/586 (30%), Positives = 270/586 (46%), Gaps = 113/586 (19%)
Query: 31 PQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATS 89
P NT G ++G + + + PV FLGVP+A PPLG+ RF P+ + W +R AT+
Sbjct: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
Query: 90 YPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDCLYLNIYAPAH--------- 131
P C QN L ML V + SEDCLYLN+Y P
Sbjct: 102 LPPACPQNLHGAL-PAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
Query: 132 -----------ADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
D G K PV+++ GG++ G+ ++FDGS LAAY +V+V + YRLG+
Sbjct: 161 EATLNPPDTDIRDPGKK-PVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVL 219
Query: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
GF +T DQ A GN+ DQ+ AL W+ +NI FGGDP +TIFG AGA V+ LILS
Sbjct: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
Query: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
++GLF KAI +SG AI + + +Y+ + +++A G + DS + CLR KPS+EL
Sbjct: 280 SEGLFQKAIAQSGTAISSW--SVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL 337
Query: 301 LTLSQKTK----SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMKEA 355
+ + +F VVDG P++P L+ Q F +IGVN E F+ E+
Sbjct: 338 VDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAES 397
Query: 356 PEILSGSNKSLALHLIQNILHIPPQYLHLVANEY------FHDKHSLTEIRDSLLDLLGD 409
+ +S S + + L+ P+ ++ + D+ + R +LL L D
Sbjct: 398 EDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTD 457
Query: 410 VFFVVPALITARYHRE----------------------------------------GATE 429
+V PA+ TA+ H + GAT+
Sbjct: 458 HQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATD 517
Query: 430 --------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYNLTE 466
+ +LS +M YW FA+TG+PN + +W +N E
Sbjct: 518 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKE 577
Query: 467 -QYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLT 511
QYL + L + + +V FW +P + + LH+ L + T
Sbjct: 578 KQYLHIGLKPRVRDNYRANKVAFWLELVPHLHN----LHTELFTTT 619
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 200 bits (508), Expect = 3e-51
Identities = 160/557 (28%), Positives = 251/557 (45%), Gaps = 108/557 (19%)
Query: 35 TRLGWIQG--KQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPN 92
T G+++G K++ +LG V ++F G+PFAAP + NPQP W +A ++
Sbjct: 31 TEGGFVEGVNKKLGLLGDSV--DIFKGIPFAAP---TKALENPQPHPGWQGTLKAKNFKK 85
Query: 93 LCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK-LPVLVWFPGGAFKT 151
CLQ + + EDCLYLNI+ P S+ LPV++W GGAF
Sbjct: 86 RCLQAT-----------ITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLM 134
Query: 152 GSAS--------IFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAAL 203
GS ++DG +A +V+VV YR+G GF +T D + PGN+ +DQ A+
Sbjct: 135 GSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAI 194
Query: 204 SWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAH 263
+WV++NI FGGDP+++T+FGESAG SVS LSP KGL +AI +SGVA+ P++
Sbjct: 195 AWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWV--- 251
Query: 264 DYEKSEDL--QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK------------S 309
+K+ + VA G D+ + +CL+ + LTL+ K
Sbjct: 252 -IQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPR-ALTLAYKVPLAGLEYPMLHYVG 309
Query: 310 FTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALH 369
F V+DG F P +P++L + A I I G NN + G + + P I G+ K
Sbjct: 310 FVPVIDGDFIPADPINLYANAA--DIDYIAGTNNMD-GHIFASIDMPAINKGNKKVTEED 366
Query: 370 LIQNILHIP-------PQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARY 422
+ + + V E + S + +++D DV F+VP I
Sbjct: 367 FYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQ 426
Query: 423 HREGATE---------------------------------------------EEKLLSRK 437
HR A +++ +S+
Sbjct: 427 HRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKA 486
Query: 438 MMKYWATFARTGNPNGNDLSL---WPAYNLTEQ-YLQLDLNM---SLGQRLKEPRVDFWT 490
M+ YW FA+TG+PN D ++ W Y YL++ M S+ + L+ + +WT
Sbjct: 487 MIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
Query: 491 STIPLILSASDMLHSPL 507
T + + +D +P+
Sbjct: 547 LTYLALPTVTDQEATPV 563
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 172 bits (435), Expect = 9e-43
Identities = 79/84 (94%), Positives = 84/84 (100%)
Query: 140 VLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQ 199
VL+WFPGGAF+TGSASIFDGS+LAAYED+LVV+VQYRLGIFGFFTTWDQHAPGNWAFKDQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 200 VAALSWVQKNIEFFGGDPSSVTIF 223
VAALSWVQKNIEFFGGDPSSVTIF
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 154 bits (389), Expect = 2e-37
Identities = 143/520 (27%), Positives = 219/520 (42%), Gaps = 86/520 (16%)
Query: 54 VNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYP 113
V+ FLGVP+AAPPL RF P+P + W +A+ C Q
Sbjct: 2225 VDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQPGTRTSTSP-------- 2275
Query: 114 KFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSAS--IFDGSALAAYEDVLVV 171
GVSEDCLYLN++ P + + VLV+F + S DGS LAA +++VV
Sbjct: 2276 --GVSEDCLYLNVFIPQNVAPNAS--VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVV 2331
Query: 172 VVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAIS 231
YR+G+FGF ++ GNW DQVAAL+WVQ +I FGGDP V++ + GA
Sbjct: 2332 TASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADV 2391
Query: 232 VSSLILSPMAKG--LFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALL 289
S +L+ A LF +A++ G A+ P + +A S S+ ++
Sbjct: 2392 ASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVV 2451
Query: 290 RCLRTKPSK-------ELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVN 342
CLR KP+ +LL +S + V+DG F P L + + + +IG +
Sbjct: 2452 SCLRQKPANVLNDAQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIG-S 2510
Query: 343 NHECGFLLPMKEAPEILSG----SNKSLALHLIQNIL--HIPPQYLHLVANEYFHDKHSL 396
+ + G + K + S+K+ +QN L + A Y+ +HS
Sbjct: 2511 SQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHST 2570
Query: 397 TEIRD---SLLDLLGDVFFVVPALITA------------RYHR-----EGATE------- 429
+ +L + D F + P + A YH G+ E
Sbjct: 2571 DDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQF 2630
Query: 430 ----------------EEKLLSRKMMKYWATFARTGNPN---------GNDLSLWPAYNL 464
EEK LS K+M+Y++ F R+GNPN + WP +
Sbjct: 2631 ALGLPFYPAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVP 2690
Query: 465 T---EQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASD 501
E Y + + Q LK+ FW+ I + +++D
Sbjct: 2691 RAGGENYKEFSELLPNRQGLKKADCSFWSKYISSLKTSAD 2730
>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
Length = 407
Score = 40.0 bits (92), Expect = 0.005
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 11/97 (11%)
Query: 141 LVWFPGGAFKTGSASIFDG--SALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198
++++ GGA GS + G + LA + +++++ YR D H+P F+D
Sbjct: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA--LFQD 165
Query: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSL 235
+ A K +E +G DPS V + GES G +V+++
Sbjct: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
>gi|16933540 fibroblast activation protein, alpha subunit [Homo
sapiens]
Length = 760
Score = 36.2 bits (82), Expect = 0.075
Identities = 46/155 (29%), Positives = 68/155 (43%), Gaps = 15/155 (9%)
Query: 109 KVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDG---SALAAY 165
K K V E L+ + P D K P+L+ GG S+F S LA+
Sbjct: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564
Query: 166 EDVLVVVVQYRLGIF-GFFTTWDQHAP-GNWAFKDQVAALSWVQKNIEFFGGDPSSVTIF 223
E +++ +V R F G + + G + +DQ+ A V+K IE D + I+
Sbjct: 565 EGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITA---VRKFIEMGFIDEKRIAIW 621
Query: 224 GESAGAISVSSLILSPMAKGLFHKAIMESGVAIIP 258
G S G VSSL L+ GLF + G+A+ P
Sbjct: 622 GWSYGGY-VSSLALA-SGTGLF-----KCGIAVAP 649
>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
Length = 401
Score = 33.9 bits (76), Expect = 0.37
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 15/94 (15%)
Query: 141 LVWFPGGAFKTGSAS--IFD--GSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAF 196
+++F GG F GS+ FD A D +VV V YRL H P F
Sbjct: 107 VIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAP-------QHHFPAQ--F 157
Query: 197 KDQVAALSW--VQKNIEFFGGDPSSVTIFGESAG 228
+D +AA+ + ++K + +G DP+ + I G+S+G
Sbjct: 158 EDGLAAVKFFLLEKILTKYGVDPTRICIAGDSSG 191
>gi|239757732 PREDICTED: similar to KIAA1654 protein [Homo sapiens]
Length = 110
Score = 33.1 bits (74), Expect = 0.64
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 10 QILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGS 69
QI + +W A P+ EGP + L W G P PV+ +L AP L +
Sbjct: 25 QICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYL-----APALNA 79
Query: 70 LRFTNPQPASPWDNLREATSYPNLCL 95
L ++ Q +S NL+ A S L L
Sbjct: 80 LLVSSLQWSSLQPNLKVAASTLTLSL 105
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 30.0 bits (66), Expect = 5.4
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 5/60 (8%)
Query: 26 PSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLR 85
P A P T W +L PVP P APPL P+PASP+ +LR
Sbjct: 644 PPAPQPAPRTLSHWS-----ALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLR 698
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 30.0 bits (66), Expect = 5.4
Identities = 43/158 (27%), Positives = 59/158 (37%), Gaps = 31/158 (19%)
Query: 226 SAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDS 285
S GAI VS+ + S + G FH + E+ A P ++ S Q A A
Sbjct: 853 SHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETA------AISR 906
Query: 286 EALLRCLRTKPSKELLTL-SQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNH 344
A + RT + ++L SQ T +F+ V P P PSI
Sbjct: 907 MAQTQRTRTSRGSDTISLASQATDTFSTV------PPTP------------PSITST--- 945
Query: 345 ECGFLLPMKEAPEIL-SGSNKSLALHLIQNILHIPPQY 381
G P E + SGS K+ LI N +P Y
Sbjct: 946 --GLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTY 981
>gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo
sapiens]
Length = 350
Score = 29.6 bits (65), Expect = 7.1
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 132 ADTGSKLPVLVWFPGGAFKTGSASIFDG--SALAAYEDVLVVVVQYRLGIFGFFTTWDQH 189
A T + P +V++ GG GS G S L D +V+ V YR F
Sbjct: 49 ASTCTLKPGIVYYHGGGGVMGSLKTHHGICSRLCKESDSVVLAVGYRKLPKHKFPV---- 104
Query: 190 APGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAG 228
+D + A K+++ +G DP+ V + G+S G
Sbjct: 105 -----PVRDCLVATIHFLKSLDAYGVDPARVVVCGDSFG 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,303,480
Number of Sequences: 37866
Number of extensions: 1006667
Number of successful extensions: 2332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2203
Number of HSP's gapped (non-prelim): 55
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.