Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 213972621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
         (1158 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]               2322   0.0  
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]               2040   0.0  
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]                2033   0.0  
gi|148839292 ATPase type 13A3 [Homo sapiens]                          789   0.0  
gi|66932949 ATPase type 13A4 [Homo sapiens]                           713   0.0  
gi|66730421 ATPase type 13A5 [Homo sapiens]                           712   0.0  
gi|170016077 ATPase type 13A1 [Homo sapiens]                          254   3e-67
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   129   2e-29
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   129   2e-29
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   129   2e-29
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   117   6e-26
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   115   2e-25
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   115   2e-25
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   115   2e-25
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   115   2e-25
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   115   2e-25
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   115   2e-25
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   115   2e-25
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   115   2e-25
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   115   3e-25
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   115   3e-25
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   111   3e-24
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   111   3e-24
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   111   3e-24
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   111   3e-24
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   111   3e-24
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...   104   4e-22
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   102   2e-21
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...   100   6e-21
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...   100   6e-21

>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 2322 bits (6018), Expect = 0.0
 Identities = 1158/1158 (100%), Positives = 1158/1158 (100%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180

Query: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240
            SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
Sbjct: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240

Query: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300
            FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
Sbjct: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300

Query: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360
            WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
Sbjct: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360

Query: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420
            AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
Sbjct: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420

Query: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
            MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
Sbjct: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480

Query: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540
            SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
Sbjct: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540

Query: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600
            LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
Sbjct: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600

Query: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660
            PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
Sbjct: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660

Query: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720
            PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
Sbjct: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720

Query: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780
            NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
Sbjct: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780

Query: 781  PASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 840
            PASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG
Sbjct: 781  PASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 840

Query: 841  ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 900
            ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ
Sbjct: 841  ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 900

Query: 901  FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 960
            FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS
Sbjct: 901  FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 960

Query: 961  LLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1020
            LLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAA
Sbjct: 961  LLLQMVLVTGVQLGGYFLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1020

Query: 1021 VSKGAPFRRPLYTNERARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEV 1080
            VSKGAPFRRPLYTNERARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEV
Sbjct: 1021 VSKGAPFRRPLYTNERARPVPPRLPAPPPAQAGLQEALQAAGTRAGRAALAAAARRPPEV 1080

Query: 1081 VQAHGHPRHWNSLPLSHQLDPSPATPPPPPPTSLRLATVYTPPPRPPPPWGSVDYCPLPW 1140
            VQAHGHPRHWNSLPLSHQLDPSPATPPPPPPTSLRLATVYTPPPRPPPPWGSVDYCPLPW
Sbjct: 1081 VQAHGHPRHWNSLPLSHQLDPSPATPPPPPPTSLRLATVYTPPPRPPPPWGSVDYCPLPW 1140

Query: 1141 TIPRRGGSPQLPSVLLSV 1158
            TIPRRGGSPQLPSVLLSV
Sbjct: 1141 TIPRRGGSPQLPSVLLSV 1158


>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
          Length = 1175

 Score = 2040 bits (5284), Expect = 0.0
 Identities = 1034/1073 (96%), Positives = 1034/1073 (96%), Gaps = 39/1073 (3%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQQAFYQV 180

Query: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240
            SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA
Sbjct: 181  SLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPYYGFQA 240

Query: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300
            FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE
Sbjct: 241  FSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEE 300

Query: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360
            WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC
Sbjct: 301  WVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYC 360

Query: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420
            AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS
Sbjct: 361  AETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHS 420

Query: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
            MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ
Sbjct: 421  MKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480

Query: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540
            SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR
Sbjct: 481  SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRR 540

Query: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600
            LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP
Sbjct: 541  LPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRP 600

Query: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660
            PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN
Sbjct: 601  PLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCN 660

Query: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720
            PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR
Sbjct: 661  PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMR 720

Query: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780
            NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ
Sbjct: 721  NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQ 780

Query: 781  PASLEFLPMESPTAVNGV---------------------------------------KVL 801
            PASLEFLPMESPTAVNGV                                       KVL
Sbjct: 781  PASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVL 840

Query: 802  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 861
            VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP
Sbjct: 841  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 900

Query: 862  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 921
            FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA
Sbjct: 901  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 960

Query: 922  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 981
            IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA
Sbjct: 961  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 1020

Query: 982  QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
            QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN
Sbjct: 1021 QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1073


>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
          Length = 1180

 Score = 2033 bits (5268), Expect = 0.0
 Identities = 1034/1078 (95%), Positives = 1034/1078 (95%), Gaps = 44/1078 (4%)

Query: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60
            MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI
Sbjct: 1    MSADSSPLVGSTPTGYGTLTIGTSIDPLSSSVSSVRLSGYCGSPWRVIGYHVVVWMMAGI 60

Query: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120
            PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS
Sbjct: 61   PLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDKEDSSWQLFTVQVQTEAIGEGSLEPS 120

Query: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA-----KRVLRYYLFQGQRYIWIETQQ 175
            PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEA     KRVLRYYLFQGQRYIWIETQQ
Sbjct: 121  PQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAVSVGQKRVLRYYLFQGQRYIWIETQQ 180

Query: 176  AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 235
            AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY
Sbjct: 181  AFYQVSLLDHGRSCDDVHRSRHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALNPY 240

Query: 236  YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 295
            YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP
Sbjct: 241  YGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRP 300

Query: 296  GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355
            GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG
Sbjct: 301  GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 360

Query: 356  LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 415
            LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK
Sbjct: 361  LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFK 420

Query: 416  FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 475
            FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC
Sbjct: 421  FYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVC 480

Query: 476  TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 535
            TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV
Sbjct: 481  TLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLV 540

Query: 536  PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 595
            PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL
Sbjct: 541  PEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL 600

Query: 596  AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 655
            AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV
Sbjct: 601  AVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELV 660

Query: 656  AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 715
            AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG
Sbjct: 661  AGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLG 720

Query: 716  LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 775
            LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH
Sbjct: 721  LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 780

Query: 776  PERGQPASLEFLPMESPTAVNGV------------------------------------- 798
            PERGQPASLEFLPMESPTAVNGV                                     
Sbjct: 781  PERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKL 840

Query: 799  --KVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 856
              KVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA
Sbjct: 841  LPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEA 900

Query: 857  SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 916
            SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD
Sbjct: 901  SVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGD 960

Query: 917  LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 976
            LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY
Sbjct: 961  LQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGY 1020

Query: 977  FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
            FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN
Sbjct: 1021 FLTLAQPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1078


>gi|148839292 ATPase type 13A3 [Homo sapiens]
          Length = 1226

 Score =  789 bits (2038), Expect = 0.0
 Identities = 461/1094 (42%), Positives = 636/1094 (58%), Gaps = 100/1094 (9%)

Query: 35   VRLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD 94
            + + GY  S W++    + V    G  LLL  W P W V+       +   E +++   D
Sbjct: 17   MEIYGYNLSRWKLAIVSLGVICSGGFLLLLLYWMPEWRVKATCVRAAIKDCEVVLLRTTD 76

Query: 95   KEDSSWQLFTVQVQTEAIGEGSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHK-SEE 153
             E   W  F  +++  ++ E     SP+S +    +  AV  +     ++  ++ K S+ 
Sbjct: 77   -EFKMW--FCAKIRVLSL-ETYPVSSPKSMSNKLSNGHAVCLIENPTEENRHRISKYSQT 132

Query: 154  AKRVLRYYLFQGQRYIWIETQQAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYG 212
              + +RY+     +Y W +T   F  +  LD G SC  ++     GL+      RK +YG
Sbjct: 133  ESQQIRYFTHHSVKYFWNDTIHNFDFLKGLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYG 192

Query: 213  PNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYK 272
             N I++ V S  +LL+ E LNP+Y FQ FS+ LW  D YY+YAL I ++S +SI  SLY 
Sbjct: 193  VNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSLYS 252

Query: 273  TRKQSQTLRDMVKL--SMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVA 330
             RKQ   L DMV    ++RV VCR   E E + S++LVPGD +V+P  G +MPCDA L+ 
Sbjct: 253  IRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLIN 312

Query: 331  GECMVNESSLTGESIPVLKTALP------EGLGP--YCAETHRRHTLFCGTLILQARAYV 382
            G C+VNES LTGES+PV KT LP      +G+G   Y  ETH+RHTLFCGT ++Q R Y 
Sbjct: 313  GTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTVIQTRFYT 372

Query: 383  GPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFIL 442
            G  V A+V RTGF T+KG LV SIL+P+P +FK Y+ +  F+  L  +A +G IY+I   
Sbjct: 373  GELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGIGFIYTIINS 432

Query: 443  YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKL 502
              N V +  I+I +LD++T+ VPPALPAAMT   +YAQ RL++ GIFCI P RIN+ G+L
Sbjct: 433  ILNEVQVGVIIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIGIFCISPQRINICGQL 492

Query: 503  QLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEP----RRLPVGPLLRALATCHALSR 558
             LVCFDKTGTLTEDGLD+ G+  ++   FL   PE       L     +  +ATCH+L++
Sbjct: 493  NLVCFDKTGTLTEDGLDLWGIQRVENARFLS--PEENVCNEMLVKSQFVACMATCHSLTK 550

Query: 559  LQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVL-AVMRP---------PLWEPQLQ 608
            ++    GDP+DLKM E+ GW+LEE    ++A   +++  V+RP         P    +++
Sbjct: 551  IEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQLLPESTPAGNQEME 610

Query: 609  AMEEPPV-PVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNPETVPTD 667
              E P    + ++ +FPFSSALQRMSVV    G  + +AY+KG+PE +AGLC PETVP D
Sbjct: 611  LFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVD 670

Query: 668  FAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQT 727
            F  +L+ +T  G+RV+ALA + L +  +    Q ++RD +E ++  +GL++M+N LK +T
Sbjct: 671  FQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIENNMDFMGLIIMQNKLKQET 730

Query: 728  TPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFL 787
              V++ L +  IR VMVTGD++ TAV+VAR CGM+ PQ+ +II  A  P+ G+ A + + 
Sbjct: 731  PAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWH 790

Query: 788  PMESPT--------------------------------AVNG--------------VKVL 801
              +S T                                A+NG               K++
Sbjct: 791  YADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLM 850

Query: 802  VQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSP 861
            + GTVFARMAP+QKT+L+  LQ + Y VGMCGDGANDCGALK A  GISLS+ EASV SP
Sbjct: 851  LHGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASP 910

Query: 862  FTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLA 921
            FTS   SI CVP +IREGR +L TSF VFK+MALYS+ Q+ SV +LY+I +NLGD QFL 
Sbjct: 911  FTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLF 970

Query: 922  IDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGGYFLTLA 981
            IDL I   V   MS       L   RPP  L+S  +L S+L Q+++  G Q  G+F    
Sbjct: 971  IDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSLGFFWVKQ 1030

Query: 982  QPWFVPL---------------------NRTVAAPDNLPNYENTVVFSLSSFQYLILAAA 1020
            QPW+                        N T     N+ NYENT VF +SSFQYLI+A A
Sbjct: 1031 QPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQYLIVAIA 1090

Query: 1021 VSKGAPFRRPLYTN 1034
             SKG PFR+P Y N
Sbjct: 1091 FSKGKPFRQPCYKN 1104


>gi|66932949 ATPase type 13A4 [Homo sapiens]
          Length = 1196

 Score =  713 bits (1840), Expect = 0.0
 Identities = 432/1058 (40%), Positives = 604/1058 (57%), Gaps = 114/1058 (10%)

Query: 59   GIPLLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRDK-EDSSWQLFTVQVQTEAIGEGSL 117
            GI  L+F W+P W V     PC+L  A+T+++   D+ +  SW+   + +   A+     
Sbjct: 44   GILPLVFYWRPAWHVWAHCVPCSLQEADTVLLRTTDEFQIYSWKK-VIWIYLSALN---- 98

Query: 118  EPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRV---LRYYLFQGQRYIWIETQ 174
                          +A G  P+       +   +   ++    +R    Q  RY+W   +
Sbjct: 99   --------------SAFGLTPDHPLMTDEEYIINRAIRKPDLKVRCIKVQKIRYVWNYLE 144

Query: 175  QAFYQVSLLDHGRSCDDVHRS-RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
              F ++  L+   S   +H+    GL+ ++Q +R+ I GPN I + V    +LL+ E LN
Sbjct: 145  GQFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLICGPNTIDVEVTPIWKLLIKEVLN 204

Query: 234  PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKL--SMRVC 291
            P+Y FQ FS+ LW ++ Y  YA  I ++S ISI L++Y  R+QS  L  +V+   S+ V 
Sbjct: 205  PFYIFQLFSVCLWFSEDYKEYAFAIIIMSIISISLTVYDLREQSVKLHHLVESHNSITVS 264

Query: 292  VC-RPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKT 350
            VC R  G +E ++S  LVPGD L+L     LMPCDA L+ G C+V+E  LTGESIPV KT
Sbjct: 265  VCGRKAGVQE-LESRVLVPGDLLILTGNKVLMPCDAVLIEGSCVVDEGMLTGESIPVTKT 323

Query: 351  ALP--EGLGPYCAET---HRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSS 405
             LP  +   P+  ++   ++RH LFCGT ++QA+A     V AVV +TGF TAKG LV S
Sbjct: 324  PLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVRS 383

Query: 406  ILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVP 465
            IL+P+P+NF+ Y+ +++F+  L   A +G IY++ +   +  P  E+V +ALD++T+ VP
Sbjct: 384  ILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAVP 443

Query: 466  PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVP 525
            PALPAA+T   +YAQ RL+++GIFCI P RIN+ G+L LVCFDKTGTLT DGLD+ GVV 
Sbjct: 444  PALPAALTTGIIYAQRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVS 503

Query: 526  LKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEE 583
                 F  +      + LP GPL  A+A+CH+L  L  T  GDP+DLKM E+T W     
Sbjct: 504  CDRNGFQEVHSFASGQALPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATTW----- 558

Query: 584  PAADSAFGTQVLAVMRPP----LWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWP 639
               + AF      +   P    + +P   A + P   +++LH+FPFSSALQRM+V+V   
Sbjct: 559  ---EMAFSGDDFHIKGVPAHAMVVKPCRTASQVPVEGIAILHQFPFSSALQRMTVIVQEM 615

Query: 640  GATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAA 699
            G  +  A++KG+PE VA  C PETVPT F   LQ YT  G+RV+ALA K L    +   A
Sbjct: 616  GGDR-LAFMKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIALAYKKL---ENDHHA 671

Query: 700  QQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGC 759
              LTR+TVE DL  LGLL++ N LK +T PV++ L   RIR VM+TGDNLQTA+TVAR  
Sbjct: 672  TTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKS 731

Query: 760  GMVAPQEHLIIVHATHPERGQPASLEFLPMESPT-------------------------- 793
            GMV+  + +I++ A        AS+ +  +E                             
Sbjct: 732  GMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSY 791

Query: 794  --AVNG--------------VKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGAN 837
              A+ G               K+L+ GT+FARM+P QK+ LV E QKL Y VGMCGDGAN
Sbjct: 792  HFALTGKSFHVISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGAN 851

Query: 838  DCGALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            DCGALK A VGISLS+ EASV SPFTS   +IECVP +I+EGR +L TSF +FKYMALYS
Sbjct: 852  DCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYS 911

Query: 898  LTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPV 957
            + Q++ VL+LY    +L + QFL  DL ITT + V M+  G    L   RP G L+S P+
Sbjct: 912  MIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRPAGRLISPPL 971

Query: 958  LSSLLLQMVLVTGVQLGGYFLTLAQPWF---------------VPLNRTVAAPDNL---- 998
            L S++  ++L   + + G+ L   QPW+                 L  +  AP+ +    
Sbjct: 972  LLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMESNS 1031

Query: 999  --PNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
               ++ENT V+ L +   + +A   SKG PFR+P YTN
Sbjct: 1032 TFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTN 1069


>gi|66730421 ATPase type 13A5 [Homo sapiens]
          Length = 1218

 Score =  712 bits (1839), Expect = 0.0
 Identities = 430/1059 (40%), Positives = 594/1059 (56%), Gaps = 117/1059 (11%)

Query: 62   LLLFRWKPLWGVRLRLRPCNLAHAETLVIEIRD-------KEDSSWQLFTVQVQTEAIGE 114
            LL+F W+P W V     PC L  A+T+++   D       K+     L T++       E
Sbjct: 48   LLVFYWRPQWRVWANCIPCPLQEADTVLLRTTDEFQRYMRKKVFCLYLSTLKFPVSKKWE 107

Query: 115  GSLEPSPQSQAEDGRSQAAVGAVPEGAWKDTAQLHKSEEAKRVLRYYLFQGQRYIWIETQ 174
             SL     S      +QA +                  + +  LR    Q  RY+W + +
Sbjct: 108  ESLVADRHSVI----NQALI------------------KPELKLRCMEVQKIRYVWNDLE 145

Query: 175  QAFYQVSLLDHGRSCDDVHRSRH-GLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
            + F +V LL+   SC D+H++   GL+ ++Q VR+ + GPN I + ++   +LLV + LN
Sbjct: 146  KRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLN 205

Query: 234  PYYGFQAFSIALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMV----KLSMR 289
            P+Y FQAF++ LWL+  Y  Y++ I +++ ISI LS+Y  R+QS  L ++V    K+ + 
Sbjct: 206  PFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVT 265

Query: 290  VCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLK 349
            + V   G EE  ++S  LVPGD L+LP +  L PCDA L+ G C+VNE  LTGESIPV K
Sbjct: 266  IIVKDKGLEE--LESRLLVPGDILILPGKFSL-PCDAVLIDGSCVVNEGMLTGESIPVTK 322

Query: 350  TALP--EGLGPY---CAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVS 404
            T LP  E   P+     E +R+H LFCGT ++Q +      V AVV +TG+ TAKG LV 
Sbjct: 323  TPLPQMENTMPWKCHSLEDYRKHVLFCGTEVIQVKPSGQGPVRAVVLQTGYNTAKGDLVR 382

Query: 405  SILHPRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVV 464
            SIL+PRP+NFK Y  + KF+  L+ L ++G  Y++ +   + VP  + V  AL L+TV V
Sbjct: 383  SILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTV 442

Query: 465  PPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVV 524
            PP LPAA+T+  +YAQ RL+++ IFCI P RIN+ G++ LVCFDKTGTLTEDGLD+ G V
Sbjct: 443  PPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTV 502

Query: 525  PLKGQAFLPL--VPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEE 582
            P     F         + +P  PL  A+A+CH+L  L  T  GDP+DLKM E T W +E+
Sbjct: 503  PTADNCFQEAHSFASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMED 562

Query: 583  EPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGAT 642
                   FGT V  +++     P  +A + P   +  L +FPFSS+LQRMSV+    G  
Sbjct: 563  CIVDSCKFGTSVSNIIK-----PGPKASKSPVEAIITLCQFPFSSSLQRMSVIAQLAGEN 617

Query: 643  QPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQL 702
                Y+KG+PE+VA  C  ETVP +F Q L+SYT  G+RV+ALA K L  + +L   + L
Sbjct: 618  HFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTL-KMGNLSEVEHL 676

Query: 703  TRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV 762
             R+ VE +L+ LGLL+M N LK +T  V++ L   RIR VM+TGDNLQTA+TVA+   M+
Sbjct: 677  AREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMI 736

Query: 763  APQEHLIIVHATHPERGQPASLEFLPMESPTAVNG------------------------- 797
             P   +IIV A  PE   PAS+ +  +E+     G                         
Sbjct: 737  PPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA 796

Query: 798  -----------------VKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCG 840
                              K+LV GTVFARM+P QK+ L+ E QKL Y VGMCGDGANDCG
Sbjct: 797  MSGKSYQVIFQHFNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCG 856

Query: 841  ALKAADVGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQ 900
            ALKAA  GISLS+ EASV SPFTS   +I+CVP +IREGR +L +SF VFKY+ +Y + Q
Sbjct: 857  ALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQ 916

Query: 901  FISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSS 960
            FIS L+LY      G+ Q+L  D+ IT  V + MS T     L   RP G LLS P+L S
Sbjct: 917  FISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYPKLAPYRPAGQLLSPPLLLS 976

Query: 961  LLLQMVLVTGVQLGGYFLTLAQPWF--------------------VPLNR-----TVAAP 995
            + L       VQ+  +     QPW+                    V L R         P
Sbjct: 977  IFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIP 1036

Query: 996  DNLPNYENTVVFSLSSFQYLILAAAVSKGAPFRRPLYTN 1034
             ++ ++E T ++ +++  Y+ +A   SKG PFR+P+YTN
Sbjct: 1037 GSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTN 1075


>gi|170016077 ATPase type 13A1 [Homo sapiens]
          Length = 1204

 Score =  254 bits (649), Expect = 3e-67
 Identities = 214/719 (29%), Positives = 349/719 (48%), Gaps = 100/719 (13%)

Query: 193 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++S  G   +D  +R A   +G N   + V  + +L  + A  P++ FQ F + LW  D 
Sbjct: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 308
           Y++Y+  +F +S + +       ++Q + + ++ K+  +  + +     +W  + S E+V
Sbjct: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318

Query: 309 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 361
           PGD + +   PQE  L+PCD  L+ G C+V+E+ LTGES+P +K  + E L P       
Sbjct: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376

Query: 362 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 412
              R H +F GT ++Q     +A  G        +A V RTGF T++G L+ +IL     
Sbjct: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 467
                  +  F+  L V A+    Y ++I       RNR  L    +    ++T VVPP 
Sbjct: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492

Query: 468 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 527
           LP  +++    +   L +  ++C  P RI   GK+++ CFDKTGTLT D L V GV  L+
Sbjct: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552

Query: 528 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 584
            G+   P+      +PV    RALA+CH+L +L D T VGDP++  M+ +  W L ++E 
Sbjct: 553 DGKEVTPV----SSIPV-ETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607

Query: 585 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 644
               +  TQ L + +                      RF F+SAL+RMSV+ ++      
Sbjct: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645

Query: 645 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 700
           +    A VKG+PE +  + +    P D+  +    +  G RV+AL  K L  + + + A+
Sbjct: 646 DLCYIAAVKGAPETLHSMFS--QCPPDYHHIHTEISREGARVLALGYKELGHL-THQQAR 702

Query: 701 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 760
           ++ R+ +E  L  +G +V+   LK  +  VI+ ++    R VM+TGDN  TA  VA+   
Sbjct: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762

Query: 761 MVAPQEHLIIVHATHP-----------------ERGQPASLE-----------FLPMESP 792
            +     LI+   +                    RG P +L               +++ 
Sbjct: 763 FIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQAT 822

Query: 793 TAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISL 851
                ++++    VFAR+AP+QK  ++  L++L Y   MCGDG ND GALK ADVG++L
Sbjct: 823 DPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 27/194 (13%)

Query: 855  EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 914
            +AS+ +PFTS ++SI+C+  VI++GRC+L T+  +FK +AL +L    S  +LY      
Sbjct: 953  DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012

Query: 915  GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 974
             D Q     L++     + +SR+ P   L R RP   + ++  + +++LQ  +       
Sbjct: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064

Query: 975  GYFLTLA-------------QPWFVPLNRTVAAPDNLPNYENTVVFSLSSFQYLILAAAV 1021
             +FL+L              Q  FV L +        P+  N+ V+ ++    +   A  
Sbjct: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFE-----PSLVNSTVYIMAMAMQMATFAIN 1118

Query: 1022 SKGAPFRRPLYTNE 1035
             KG PF   L  N+
Sbjct: 1119 YKGPPFMESLPENK 1132


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
           sapiens]
          Length = 1023

 Score =  129 bits (324), Expect = 2e-29
 Identities = 210/883 (23%), Positives = 357/883 (40%), Gaps = 110/883 (12%)

Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
           +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 38  EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96

Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
               F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 97  ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152

Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
           K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211

Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
            V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 212 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261

Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
           G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 262 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318

Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
            E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 319 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377

Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
           TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 378 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432

Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
            +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 433 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486

Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
           +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 487 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546

Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606

Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL---------IIVHATHPERGQPASLE 785
           R   I+ +MVTGD+  TA  +A+G G+++              I V   +P   +   + 
Sbjct: 607 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVH 666

Query: 786 FLPMESPTAVNGVKVLVQGT--VFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALK 843
              ++  T+     +L   T  VFAR +P+QK  +V   Q+    V + GDG ND  ALK
Sbjct: 667 GSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALK 726

Query: 844 AADVGISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLT 899
            AD+G+++  A  S VS   + M  ++     +   + EGR   D      K    Y+LT
Sbjct: 727 KADIGVAMGIA-GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDN----LKKSIAYTLT 781

Query: 900 QFIS------VLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRP----P 949
             I       + I+  I   LG +  L IDL      A+ ++       + + +P     
Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKT 841

Query: 950 GALLSVPVLSSLLLQMVLVTGVQLGG---YFLTLAQPWFVPLN 989
             L++  ++S    Q+ ++    LGG   YF+ LA+  F+P++
Sbjct: 842 DKLVNERLISMAYGQIGMIQA--LGGFFTYFVILAENGFLPIH 882


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score =  129 bits (324), Expect = 2e-29
 Identities = 210/883 (23%), Positives = 357/883 (40%), Gaps = 110/883 (12%)

Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
           +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 7   EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 65

Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
               F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 66  ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 121

Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
           K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 122 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 180

Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
            V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 181 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 230

Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
           G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 231 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 287

Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
            E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 288 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 346

Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
           TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 347 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 401

Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
            +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 402 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 455

Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
           +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 456 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 515

Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 516 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 575

Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL---------IIVHATHPERGQPASLE 785
           R   I+ +MVTGD+  TA  +A+G G+++              I V   +P   +   + 
Sbjct: 576 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVH 635

Query: 786 FLPMESPTAVNGVKVLVQGT--VFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALK 843
              ++  T+     +L   T  VFAR +P+QK  +V   Q+    V + GDG ND  ALK
Sbjct: 636 GSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALK 695

Query: 844 AADVGISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLT 899
            AD+G+++  A  S VS   + M  ++     +   + EGR   D      K    Y+LT
Sbjct: 696 KADIGVAMGIA-GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDN----LKKSIAYTLT 750

Query: 900 QFIS------VLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRP----P 949
             I       + I+  I   LG +  L IDL      A+ ++       + + +P     
Sbjct: 751 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKT 810

Query: 950 GALLSVPVLSSLLLQMVLVTGVQLGG---YFLTLAQPWFVPLN 989
             L++  ++S    Q+ ++    LGG   YF+ LA+  F+P++
Sbjct: 811 DKLVNERLISMAYGQIGMIQA--LGGFFTYFVILAENGFLPIH 851


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  129 bits (324), Expect = 2e-29
 Identities = 210/883 (23%), Positives = 357/883 (40%), Gaps = 110/883 (12%)

Query: 179 QVSLLDHGRSCDDVHRS-----RHGLSLQDQMVRKAIYGPNVISIPVKSYPQLLVDEALN 233
           +VS+ DH  S D++HR        GL+        A  GPN ++ P  +   +     L 
Sbjct: 38  EVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQL- 96

Query: 234 PYYGFQAFSIALWLADHYYWYALCI----------------FLISSISI---CLSLYKTR 274
               F  FS+ LW+     + A  I                 ++S++ I   C S Y+  
Sbjct: 97  ----FGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 152

Query: 275 KQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALV-AGEC 333
           K S+ +     +  +  +    GE+  +++ E+V GD LV  + G  +P D  ++ A  C
Sbjct: 153 KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGD-LVEVKGGDRIPADLRIISANGC 211

Query: 334 MVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRT 393
            V+ SSLTGES P  +T  P+       ET  R+  F  T  ++  A        +V  T
Sbjct: 212 KVDNSSLTGESEP--QTRSPDFTNENPLET--RNIAFFSTNCVEGTAR------GIVVYT 261

Query: 394 GFCTAKGGL--VSSILH--PRPINFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPL 449
           G  T  G +  ++S L     PI  +  +H +  +  ++V   LG  + I  L      L
Sbjct: 262 GDRTVMGRIATLASGLEGGQTPIAAEI-EHFIHIITGVAVF--LGVSFFILSLILEYTWL 318

Query: 450 NEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDK 509
            E VI  + ++   VP  L A +TVC      R+ R+     +   +   G    +C DK
Sbjct: 319 -EAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDK 377

Query: 510 TGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMD 569
           TGTLT++    M V  +     +               +  AT  ALSR+    + +   
Sbjct: 378 TGTLTQNR---MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRI--AGLCNRAV 432

Query: 570 LKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSAL 629
            +  +    +L+   A D++    +  +      E    +++E     + +   PF+S  
Sbjct: 433 FQANQENLPILKRAVAGDASESALLKCI------ELCCGSVKEMRERYAKIVEIPFNSTN 486

Query: 630 QRMSVVVAWPGATQPE--AYVKGSPELVAGLCN-----------PETVPTDFAQMLQSYT 676
           +    +   P  ++P+    +KG+PE +   C+            E +   F        
Sbjct: 487 KYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELG 546

Query: 677 AAGYRVVALASKPLPTVPSLEAAQQLTRDT--VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G RV+      LP     E  Q  T D      +L  +GL+ M +  +      +   
Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKC 606

Query: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL---------IIVHATHPERGQPASLE 785
           R   I+ +MVTGD+  TA  +A+G G+++              I V   +P   +   + 
Sbjct: 607 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVH 666

Query: 786 FLPMESPTAVNGVKVLVQGT--VFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALK 843
              ++  T+     +L   T  VFAR +P+QK  +V   Q+    V + GDG ND  ALK
Sbjct: 667 GSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALK 726

Query: 844 AADVGISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSLDTSFSVFKYMALYSLT 899
            AD+G+++  A  S VS   + M  ++     +   + EGR   D      K    Y+LT
Sbjct: 727 KADIGVAMGIA-GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDN----LKKSIAYTLT 781

Query: 900 QFIS------VLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRP----P 949
             I       + I+  I   LG +  L IDL      A+ ++       + + +P     
Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKT 841

Query: 950 GALLSVPVLSSLLLQMVLVTGVQLGG---YFLTLAQPWFVPLN 989
             L++  ++S    Q+ ++    LGG   YF+ LA+  F+P++
Sbjct: 842 DKLVNERLISMAYGQIGMIQA--LGGFFTYFVILAENGFLPIH 882


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score =  117 bits (293), Expect = 6e-26
 Identities = 179/776 (23%), Positives = 302/776 (38%), Gaps = 104/776 (13%)

Query: 212 GPNVISIP------VKSYPQLLVDEALNPYYG----FQAFSIALWLADHYYWYALCIFLI 261
           GPN ++ P      VK   QL    +L  + G    F A+SI ++  +      L + ++
Sbjct: 84  GPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIV 143

Query: 262 SSISI----CLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVLPQ 317
            S+ +    C S Y+  K S+ +     +  +  +   GGE+  ++  E+V GD LV  +
Sbjct: 144 LSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGD-LVEIK 202

Query: 318 EGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFCGTLIL 376
            G  +P D  L++ + C V+ SSLTGES P  ++  P+       ET  R+  F  T  +
Sbjct: 203 GGDRVPADLRLISAQGCKVDNSSLTGESEPQSRS--PDFTHENPLET--RNICFFSTNCV 258

Query: 377 QARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSVLAL-LGT 435
           +  A        +V  TG  T  G + S                  F+  ++V+A+ LG 
Sbjct: 259 EGTAR------GIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGV 312

Query: 436 IYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLR 495
            +    L      L E +I  + ++   VP  L A +TVC      R+ R+     +   
Sbjct: 313 TFFALSLLLGYGWL-EAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEA 371

Query: 496 INLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHA 555
           +   G    +C DKTGTLT++    M V  +     +               ++  T   
Sbjct: 372 VETLGSTSTICSDKTGTLTQNR---MTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFM 428

Query: 556 LSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPV 615
           L+R+    + +  D K  +    + +     D++    +  +      E    ++ E   
Sbjct: 429 LARI--AGLCNRADFKANQEILPIAKRATTGDASESALLKFI------EQSYSSVAEMRE 480

Query: 616 PVSVLHRFPFSSALQ-RMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ET 663
               +   PF+S  + +MS+ +    +      +KG+PE +   C+            + 
Sbjct: 481 KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE 540

Query: 664 VPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDTVE---GDLSLLGLLVMR 720
           +   F          G RV+      LP+  S         D +     +L  +GL+ M 
Sbjct: 541 MKEAFQNAYLELGGLGERVLGFCFLNLPS--SFSKGFPFNTDEINFPMDNLCFVGLISMI 598

Query: 721 NLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMV------------------ 762
           +  +      +   R   I+ +MVTGD+  TA  +A+G G++                  
Sbjct: 599 DPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPI 658

Query: 763 ----APQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTEL 818
               A     I+VH    +  Q   L+ +    P             VFAR +P+QK  +
Sbjct: 659 SKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPE-----------IVFARTSPQQKLII 707

Query: 819 VCELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----CVPM 874
           V   Q+L   V + GDG ND  ALK AD+GI++     S VS   + M  ++     +  
Sbjct: 708 VEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMG-ISGSDVSKQAADMILLDDNFASIVT 766

Query: 875 VIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDL 924
            + EGR   D      K   +Y+LT  I       + I+  I   LG +  L IDL
Sbjct: 767 GVEEGRLIFDN----LKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  115 bits (289), Expect = 2e-25
 Identities = 182/751 (24%), Positives = 289/751 (38%), Gaps = 99/751 (13%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALV---AGECMVNESSLTGESIPVLK--TALPEGL 356
           + + ++VPGD +V    G  +P D  L+   +    V++S LTGES+ V K   A+P+  
Sbjct: 140 IRARDIVPGD-IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPD-- 196

Query: 357 GPYCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI--LHPR--PI 412
            P      +++ LF GT I   +A      + V   TG  T  G + S +  + P   P+
Sbjct: 197 -PRAVNQDKKNMLFSGTNITSGKA------VGVAVATGLHTELGKIRSQMAAVEPERTPL 249

Query: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVV 463
             K  +   +   A+SV+ +   + +I             R  V   +I   A+ L    
Sbjct: 250 QRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKI---AVALAVAA 306

Query: 464 VPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV--M 521
           +P  LPA +T C      R+ R+         +   G   ++C DKTGTLT + + V  M
Sbjct: 307 IPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 366

Query: 522 GVVP-------------LKGQAFLP-----LVPEPRRLPVGPLLRALATCHALSRLQDTP 563
            VV              + G  + P        +P R      L  LAT  AL       
Sbjct: 367 FVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALD 426

Query: 564 VGDPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLH 621
             +   +  K+ E+T   L       + F T + A+ R       ++        +  L 
Sbjct: 427 YNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSR-------VERAGACNTVIKQLM 479

Query: 622 RFPFSSALQR----MSVVVA----WPGATQPEAYVKGSPELVAGLCNPETV--------P 665
           R  F+    R    MSV        P     + +VKG+PE V   C+   V        P
Sbjct: 480 RKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTP 539

Query: 666 TDFAQMLQSYTAAG-----YRVVALASKPLPT-VPSLEAAQQLTRDTVEGDLSLLGLLVM 719
           T   Q+L      G      R +ALA++  P     +E          E DL+ +G + M
Sbjct: 540 TSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGM 599

Query: 720 RNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERG 779
            +  +P+    I    +  IR VM+TGDN  TAV + R  G+    E +     T  E  
Sbjct: 600 LDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFD 659

Query: 780 QPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDC 839
                +  P +   A    +       FAR+ P  K+ +V  LQ       M GDG ND 
Sbjct: 660 -----DLSPEQQRQACRTARC------FARVEPAHKSRIVENLQSFNEITAMTGDGVNDA 708

Query: 840 GALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYS 897
            ALK A++GI++    A A   +    S  +   +   + EGR          +Y+   +
Sbjct: 709 PALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSN 768

Query: 898 LTQFISVLI--LYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSV 955
           + + + + +  +  +   L  +Q L ++LV     A  +    P L +    P       
Sbjct: 769 VGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSP--RE 826

Query: 956 PVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
            ++S  L    L  GV +G   +  A  WFV
Sbjct: 827 ALISGWLFFRYLAIGVYVGLATVAAATWWFV 857


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  115 bits (289), Expect = 2e-25
 Identities = 186/818 (22%), Positives = 333/818 (40%), Gaps = 99/818 (12%)

Query: 189 CDDVHRSRHGLSLQDQMVRKAIYGPNVI----SIPV-KSYPQLLVDEALNPYYGFQAFSI 243
           C D+H    GLS      R+  +G N      S PV K Y    +D+  NP       S 
Sbjct: 70  CVDLHT---GLSEFSVTQRRLAHGWNEFVADNSEPVWKKY----LDQFKNPLILLLLGSA 122

Query: 244 ALWLADHYYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVD 303
            + +    Y  A+ I     + + ++  +  +  ++L ++ K+    C C   G+ + + 
Sbjct: 123 LVSVLTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECNCLREGKLQHLL 182

Query: 304 SSELVPGDCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALP-EGLGPYCA 361
           + ELVPGD + L   G  +P D  L    + +V+ESS TGE+ P  KT  P  G G    
Sbjct: 183 ARELVPGDVVSL-SIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDL-- 239

Query: 362 ETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSM 421
            T   + +F GTL+   R         VV  TG  +++ G V  ++          + SM
Sbjct: 240 -TTLSNIVFMGTLVQYGRGQ------GVVIGTGE-SSQFGEVFKMMQAEETPKTPLQKSM 291

Query: 422 KFVAALSVLALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQ 480
             +     L   G I  I ++ +     L  +    + L    +P  LP  + V  +   
Sbjct: 292 DRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGV 351

Query: 481 SRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKG-QAFLPLVPEPR 539
            R+ ++ +       +   G   ++C DKTGTLT + + V  +V   G +A +  V    
Sbjct: 352 LRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDG 411

Query: 540 RLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMR 599
           +  V      L +   +    +  VG  ++   V +   + +         G  +   M+
Sbjct: 412 QGTVC----LLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMK 467

Query: 600 PPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAY-VKGSPELVAGL 658
             L + +   + +  +P        FSS  + M+V  +     Q + Y +KG+ E V   
Sbjct: 468 MDLSDIKNSYIRKKEIP--------FSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRY 519

Query: 659 C---NPETVPTDFAQMLQSYT--------AAGYRVVALASKPLPTVPSLEAAQQLTRDTV 707
           C   N   +P       +S+         + G RV+ALAS P                  
Sbjct: 520 CTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGP-----------------E 562

Query: 708 EGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEH 767
            G L+ LGL+ + +  +      +Q L  + +   M+TGD L+TA+ + R  G+      
Sbjct: 563 LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLC----- 617

Query: 768 LIIVHATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQY 827
                      G+  ++    ++S         + + +VF R +P+ K +++  LQ+   
Sbjct: 618 ----------NGKLQAMSGEEVDSVEKGELADRVGKVSVFFRTSPKHKLKIIKALQESGA 667

Query: 828 CVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE----CVPMVIREGRCSL 883
            V M GDG ND  ALK+AD+GI++ Q   + VS   ++M  ++     +   + EG+   
Sbjct: 668 IVAMTGDGVNDAVALKSADIGIAMGQT-GTDVSKEAANMILVDDDFSAIMNAVEEGK--- 723

Query: 884 DTSFSVFKYMALYSLTQFISVLILYTINT------NLGDLQFLAIDLVITTTVAVLMSRT 937
              F   K    + L+  IS L L T++T       L  +Q L I++++    A  +   
Sbjct: 724 -GIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLG-V 781

Query: 938 GPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLGG 975
            P       +PP ++    +  +L+L++++   + + G
Sbjct: 782 EPVDKDAFRQPPRSVRDTILSRALILKILMSAAIIISG 819


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score =  115 bits (287), Expect = 3e-25
 Identities = 172/755 (22%), Positives = 289/755 (38%), Gaps = 107/755 (14%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALVAGECM---VNESSLTGESIPVLKTALPEGLGP 358
           + + ++VPGD +V    G  +P D  ++A +     V++S LTGES+ V+K   P    P
Sbjct: 140 IKARDIVPGD-IVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVP-DP 197

Query: 359 YCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPR----PINF 414
                 +++ LF GT I   +A      L +V  TG  T  G +   +        P+  
Sbjct: 198 RAVNQDKKNMLFSGTNIAAGKA------LGIVATTGVGTEIGKIRDQMAATEQDKTPLQQ 251

Query: 415 KFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVVVP 465
           K  +   +    +S++ +   + +I            +R  +   +I   A+ L    +P
Sbjct: 252 KLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKI---AVALAVAAIP 308

Query: 466 PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV----- 520
             LPA +T C      R+ ++         +   G   ++C DKTGTLT + + V     
Sbjct: 309 EGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFI 368

Query: 521 ----------MGVVPLKGQAFLP---LVPEPRRLPVGPL--LRALATCHALSRLQDTPVG 565
                     +    + G  + P   ++   + +  G    L  LAT  AL         
Sbjct: 369 IDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFN 428

Query: 566 DPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHR- 622
           +   +  K+ E+T   L       + F T V +          L  +E      SV+ + 
Sbjct: 429 EAKGVYEKVGEATETALTTLVEKMNVFNTDVRS----------LSKVERANACNSVIRQL 478

Query: 623 ----FPFSSALQRMSVVVAWPGATQPEA------YVKGSPELVAGLCNPETVPTDFAQML 672
               F    +  R S+ V    A    A      +VKG+PE V   CN   V T    + 
Sbjct: 479 MKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLT 538

Query: 673 QSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDT-----------------VEGDLSLLG 715
                    V+        T+  L  A   TRDT                  E DL+ +G
Sbjct: 539 GPVKEKIMAVIKEWGTGRDTLRCLALA---TRDTPPKREEMVLDDSARFLEYETDLTFVG 595

Query: 716 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 775
           ++ M +  + + T  IQ  R   IR +M+TGDN  TA+ + R  G+    E +     T 
Sbjct: 596 VVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTG 655

Query: 776 PERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDG 835
            E       + LP+         +   +   FAR+ P  K+++V  LQ       M GDG
Sbjct: 656 RE------FDDLPLAEQR-----EACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDG 704

Query: 836 ANDCGALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYM 893
            ND  ALK A++GI++    A A   S    +  +   +   + EGR   +      +Y+
Sbjct: 705 VNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYL 764

Query: 894 ALYSLTQFISVLILYTIN--TNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGA 951
              ++ + + + +   +     L  +Q L ++LV     A  +    P L +   RPP +
Sbjct: 765 ISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDI-MDRPPRS 823

Query: 952 LLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
               P++S  L    +  G  +G   +  A  WF+
Sbjct: 824 -PKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFL 857


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score =  115 bits (287), Expect = 3e-25
 Identities = 172/755 (22%), Positives = 289/755 (38%), Gaps = 107/755 (14%)

Query: 302 VDSSELVPGDCLVLPQEGGLMPCDAALVAGECM---VNESSLTGESIPVLKTALPEGLGP 358
           + + ++VPGD +V    G  +P D  ++A +     V++S LTGES+ V+K   P    P
Sbjct: 140 IKARDIVPGD-IVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVP-DP 197

Query: 359 YCAETHRRHTLFCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPR----PINF 414
                 +++ LF GT I   +A      L +V  TG  T  G +   +        P+  
Sbjct: 198 RAVNQDKKNMLFSGTNIAAGKA------LGIVATTGVGTEIGKIRDQMAATEQDKTPLQQ 251

Query: 415 KFYKHSMKFVAALSVLALLGTIYSIFIL---------YRNRVPLNEIVIRALDLVTVVVP 465
           K  +   +    +S++ +   + +I            +R  +   +I   A+ L    +P
Sbjct: 252 KLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKI---AVALAVAAIP 308

Query: 466 PALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDV----- 520
             LPA +T C      R+ ++         +   G   ++C DKTGTLT + + V     
Sbjct: 309 EGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFI 368

Query: 521 ----------MGVVPLKGQAFLP---LVPEPRRLPVGPL--LRALATCHALSRLQDTPVG 565
                     +    + G  + P   ++   + +  G    L  LAT  AL         
Sbjct: 369 IDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFN 428

Query: 566 DPMDL--KMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHR- 622
           +   +  K+ E+T   L       + F T V +          L  +E      SV+ + 
Sbjct: 429 EAKGVYEKVGEATETALTTLVEKMNVFNTDVRS----------LSKVERANACNSVIRQL 478

Query: 623 ----FPFSSALQRMSVVVAWPGATQPEA------YVKGSPELVAGLCNPETVPTDFAQML 672
               F    +  R S+ V    A    A      +VKG+PE V   CN   V T    + 
Sbjct: 479 MKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLT 538

Query: 673 QSYTAAGYRVVALASKPLPTVPSLEAAQQLTRDT-----------------VEGDLSLLG 715
                    V+        T+  L  A   TRDT                  E DL+ +G
Sbjct: 539 GPVKEKIMAVIKEWGTGRDTLRCLALA---TRDTPPKREEMVLDDSARFLEYETDLTFVG 595

Query: 716 LLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATH 775
           ++ M +  + + T  IQ  R   IR +M+TGDN  TA+ + R  G+    E +     T 
Sbjct: 596 VVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTG 655

Query: 776 PERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDG 835
            E       + LP+         +   +   FAR+ P  K+++V  LQ       M GDG
Sbjct: 656 RE------FDDLPLAEQR-----EACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDG 704

Query: 836 ANDCGALKAADVGISLSQ--AEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYM 893
            ND  ALK A++GI++    A A   S    +  +   +   + EGR   +      +Y+
Sbjct: 705 VNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYL 764

Query: 894 ALYSLTQFISVLILYTIN--TNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGA 951
              ++ + + + +   +     L  +Q L ++LV     A  +    P L +   RPP +
Sbjct: 765 ISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDI-MDRPPRS 823

Query: 952 LLSVPVLSSLLLQMVLVTGVQLGGYFLTLAQPWFV 986
               P++S  L    +  G  +G   +  A  WF+
Sbjct: 824 -PKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFL 857


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  111 bits (278), Expect = 3e-24
 Identities = 173/760 (22%), Positives = 299/760 (39%), Gaps = 90/760 (11%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKAK------GVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+   LG    ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPIVETLGC-CNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNPETVP 665
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 666 TDFAQMLQSYT-----------AAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
                + Q              +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGM 831
              + +  Q  S E +       ++  +++ +  VF R +P  K +++  LQK    V M
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLS--QIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAM 641

Query: 832 CGDGANDCGALKAADVGISLSQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--S 886
            GDG ND  ALKAAD+G+++ Q    V       +      + +   I EG+   +   +
Sbjct: 642 TGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKN 701

Query: 887 FSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVI 926
           F  F+     +    IS+  L      L  +Q L I++++
Sbjct: 702 FVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  111 bits (278), Expect = 3e-24
 Identities = 173/760 (22%), Positives = 299/760 (39%), Gaps = 90/760 (11%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKAK------GVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+   LG    ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPIVETLGC-CNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNPETVP 665
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 666 TDFAQMLQSYT-----------AAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
                + Q              +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGM 831
              + +  Q  S E +       ++  +++ +  VF R +P  K +++  LQK    V M
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLS--QIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAM 641

Query: 832 CGDGANDCGALKAADVGISLSQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--S 886
            GDG ND  ALKAAD+G+++ Q    V       +      + +   I EG+   +   +
Sbjct: 642 TGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKN 701

Query: 887 FSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVI 926
           F  F+     +    IS+  L      L  +Q L I++++
Sbjct: 702 FVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  111 bits (278), Expect = 3e-24
 Identities = 173/760 (22%), Positives = 299/760 (39%), Gaps = 90/760 (11%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKAK------GVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+   LG    ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPIVETLGC-CNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNPETVP 665
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 666 TDFAQMLQSYT-----------AAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
                + Q              +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGM 831
              + +  Q  S E +       ++  +++ +  VF R +P  K +++  LQK    V M
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLS--QIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAM 641

Query: 832 CGDGANDCGALKAADVGISLSQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--S 886
            GDG ND  ALKAAD+G+++ Q    V       +      + +   I EG+   +   +
Sbjct: 642 TGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKN 701

Query: 887 FSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVI 926
           F  F+     +    IS+  L      L  +Q L I++++
Sbjct: 702 FVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  111 bits (278), Expect = 3e-24
 Identities = 173/760 (22%), Positives = 299/760 (39%), Gaps = 90/760 (11%)

Query: 196 RHGLSLQDQMVRKAIYGPNVISIPV-----KSYPQLLVDEALNPYYGFQAFSIALWLADH 250
           ++GL+  +   R+A +G N   I       K Y    + +  NP       S  + +  H
Sbjct: 43  QNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKY----ISQFKNPLIMLLLASAVISVLMH 98

Query: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPG 310
            +  A+ I +   I + ++  +  +  ++L ++ KL    C C   G+ E   + +LVPG
Sbjct: 99  QFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPG 158

Query: 311 DCLVLPQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTL 369
           D + L   G  +P D  L  A +  ++ESSLTGE+ P  K   P+          R +  
Sbjct: 159 DTVCL-SVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIA 217

Query: 370 FCGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSILHPRPINFKFYKHSMKFVAALSV 429
           F GTL+   +A        VV  TG   ++ G V  ++          + SM  +     
Sbjct: 218 FMGTLVRCGKAK------GVVIGTGE-NSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLS 270

Query: 430 LALLGTIYSIFIL-YRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRL-RRQG 487
               G I  I ++ +     + E+   ++ L    +P  LP  +TV       R+ +++ 
Sbjct: 271 FYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 330

Query: 488 IFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLL 547
           I    P+   LG    ++C DKTGTLT++ + V  +    G     L  E   +      
Sbjct: 331 IVKKLPIVETLGC-CNVICSDKTGTLTKNEMTVTHIFTSDG-----LHAEVTGVGYNQFG 384

Query: 548 RALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQL 607
             +     +    +  V   ++   V +   +           G  +   M+  L   Q 
Sbjct: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQ 444

Query: 608 QAMEEPPVPVSVLHRFPFSSALQRMSV-VVAWPGATQPE-AYVKGSPELVAGLCNPETVP 665
             + +          +PFSS  + M+V  V      +PE  ++KG+ E V   C      
Sbjct: 445 DYIRKA--------EYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSK 496

Query: 666 TDFAQMLQSYT-----------AAGYRVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLL 714
                + Q              +AG RV+ALAS P                   G L+ L
Sbjct: 497 GQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGP-----------------ELGQLTFL 539

Query: 715 GLLVMRNLLKPQTTPVIQA---LRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
           GL+    ++ P  T V +A   L  + +   M+TGD+ +TAV +A   G+          
Sbjct: 540 GLV---GIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL---------- 586

Query: 772 HATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGM 831
              + +  Q  S E +       ++  +++ +  VF R +P  K +++  LQK    V M
Sbjct: 587 ---YSKTSQSVSGEEIDAMDVQQLS--QIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAM 641

Query: 832 CGDGANDCGALKAADVGISLSQAEASVVSPFTSSMA---SIECVPMVIREGRCSLDT--S 886
            GDG ND  ALKAAD+G+++ Q    V       +      + +   I EG+   +   +
Sbjct: 642 TGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKN 701

Query: 887 FSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVI 926
           F  F+     +    IS+  L      L  +Q L I++++
Sbjct: 702 FVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  111 bits (278), Expect = 3e-24
 Identities = 191/843 (22%), Positives = 347/843 (41%), Gaps = 105/843 (12%)

Query: 212 GPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADHYYWYALCIFLISSISICLS-- 269
           GPN ++ P K  P+++  + L    G   FSI LW+     W A  I   S  S  L+  
Sbjct: 91  GPNSLT-PPKQTPEIV--KFLKQMVG--GFSILLWVGAFLCWIAYGIQYSSDKSASLNNV 145

Query: 270 -----------------LYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDC 312
                             Y+  K +  +    K+  +  +     E++ + S +LV GD 
Sbjct: 146 YLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGD- 204

Query: 313 LVLPQEGGLMPCDAALVAGE-CMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLFC 371
           +V  + G  +P D  +++ + C V+ SSLTGES P           P  +E    + L  
Sbjct: 205 IVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQ----------PRSSEFTHENPLET 254

Query: 372 GTLILQARAYVGPHVLAVVTRTGFCTAKG---GLVSSILHPR-PINFKFYKHSMKFVAAL 427
             +   +   +   V  +V  TG  T  G    L S + + + PI  +  +H +  VA +
Sbjct: 255 KNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEI-EHFVHIVAGV 313

Query: 428 SV-LALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQ 486
           +V + +L  I ++ + Y+    + + +I  + ++   VP  L A +TV       R+ ++
Sbjct: 314 AVSIGILFFIIAVSLKYQ----VLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKK 369

Query: 487 GIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPL 546
                +   +   G   ++C DKTGTLT++ + V  +     Q F+    E     V   
Sbjct: 370 NCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLW-FDNQIFVADTSEDHSNQVFD- 427

Query: 547 LRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFGTQVLA---VMRPPLW 603
            ++  T  +LS++    + +  + K  +    ++++    D++  T +L    V+   + 
Sbjct: 428 -QSSRTWASLSKI--ITLCNRAEFKPGQENVPIMKKAVIGDAS-ETALLKFSEVILGDVM 483

Query: 604 EPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLC---- 659
           E + +  +   +P +  ++F  S  +  M      P   +    +KG+PE +   C    
Sbjct: 484 EIRKRNRKVAEIPFNSTNKFQLS--IHEMDD----PHGKRFLMVMKGAPERILEKCSTIM 537

Query: 660 -NPETVPTDFAQMLQSYTA------AGYRVVALASKPLPT--VPSLEAAQQLTRDTVEGD 710
            N E  P D +     +TA       G RV+      LP    P   +      +    +
Sbjct: 538 INGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSN 597

Query: 711 LSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL-- 768
           L  +GLL M +  +      +   R   I+ +MVTGD+  TA  +A+  G+++       
Sbjct: 598 LCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVE 657

Query: 769 -------IIVHATHPERGQPASLEFLPMESPTAVNGVKVLV--QGTVFARMAPEQKTELV 819
                  I V   +    + A +  + ++  ++    ++L   Q  VFAR +P+QK  +V
Sbjct: 658 DIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIV 717

Query: 820 CELQKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMA---SIECVPMVI 876
              Q+    V + GDG ND  ALK AD+GI++  A +         +    +   +   +
Sbjct: 718 EGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGV 777

Query: 877 REGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDL--VITT 928
            EGR   D      K    YSLT+ I+      + I+  +   +G +  L IDL   I  
Sbjct: 778 EEGRLIFDN----LKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIP 833

Query: 929 TVAVLMSRTGPALVLGRVRPPG--ALLSVP--VLSSLLLQMVLVTGVQLGGYFLTLAQPW 984
           ++A+   +    ++  + R      L++ P  V S L + ++   G  L  YF   AQ  
Sbjct: 834 SIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFL-VYFTVYAQEG 892

Query: 985 FVP 987
           F+P
Sbjct: 893 FLP 895


>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
           sapiens]
          Length = 1243

 Score =  104 bits (260), Expect = 4e-22
 Identities = 147/702 (20%), Positives = 278/702 (39%), Gaps = 68/702 (9%)

Query: 296 GGEEEWVDSSELVPGDCLVLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEG 355
           G EEE  D   +  GD L LP   G    +AA  A   +VN     G ++   ++   + 
Sbjct: 293 GEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDG-NVDASQSKAKQQ 351

Query: 356 LGPYCAETHRRHTLFCGTLILQARAYVGPHVLAVV----TRTGFCTAKGGLVSSILHPRP 411
            G    E     +   G    + +A +     +V+    T+      K GLV S +    
Sbjct: 352 DGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAI--TV 409

Query: 412 INFKFYKHSMKFVAALSVLALLGTIYSIFILYRNRVPLNEIVIRALDLVTVVVPPALPAA 471
           I    Y     FV  ++    L     +++ Y       +  I  + ++ V VP  LP A
Sbjct: 410 IILVLYFTVDTFV--VNKKPWLPECTPVYVQY-----FVKFFIIGVTVLVVAVPEGLPLA 462

Query: 472 MTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKGQAF 531
           +T+   Y+  ++ +      H       G    +C DKTGTLT + + V  V    G   
Sbjct: 463 VTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTV--VQAYVGDVH 520

Query: 532 LPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLEEEPAADSAFG 591
              +P+P  +     +  L    A++    T +  P      E  G  L  +    +  G
Sbjct: 521 YKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------EKEG-ALPRQVGNKTECG 572

Query: 592 TQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGS 651
                +     +EP    M E      +   + F+S  + MS V+  P  +    Y KG+
Sbjct: 573 LLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMSTVIKLPDESF-RMYSKGA 627

Query: 652 PELVAGLC-------------NPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEA 698
            E+V   C              P        ++++     G R + +A +  P+ P  + 
Sbjct: 628 SEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW 687

Query: 699 AQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARG 758
             +   + +  +L+ + ++ + + ++P+    I+  +R  I   MVTGDN+ TA  +A  
Sbjct: 688 DNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIK 744

Query: 759 CGMVAPQEHLIIVHA---THPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQK 815
           CG++ P E  + +         R +   +E   ++        K+  +  V AR +P  K
Sbjct: 745 CGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERID--------KIWPKLRVLARSSPTDK 796

Query: 816 TELVCEL-----QKLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE 870
             LV  +      + +  V + GDG ND  ALK ADVG ++  A   V    +  + + +
Sbjct: 797 HTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDD 856

Query: 871 CVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILY-----TINTNLGDLQFLAIDLV 925
               +++      +   S+ K++        ++V++ +     T ++ L  +Q L ++L+
Sbjct: 857 NFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLI 916

Query: 926 ITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 967
           + T  ++ ++   P   L   +P G   + P++S  +++ +L
Sbjct: 917 MDTFASLALATEPPTETLLLRKPYGR--NKPLISRTMMKNIL 956



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   +  +E+V GD +  
Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D   + G +  ++ESSLTGES  V K+
Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  102 bits (255), Expect = 2e-21
 Identities = 113/540 (20%), Positives = 222/540 (41%), Gaps = 54/540 (10%)

Query: 454 IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
           I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 400 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 459

Query: 514 TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
           T + + V  V    G      +P+P  +     +  L    A++    T +  P      
Sbjct: 460 TTNRMTV--VQAYVGDVHYKEIPDPSSINT-KTMELLINAIAINSAYTTKILPP------ 510

Query: 574 ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMS 633
           E  G  L  +    +  G     +     +EP    M E      +   + F+S  + MS
Sbjct: 511 EKEG-ALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEE----KLYKVYTFNSVRKSMS 565

Query: 634 VVVAWPGATQPEAYVKGSPELVAGLC-------------NPETVPTDFAQMLQSYTAAGY 680
            V+  P  +    Y KG+ E+V   C              P        ++++     G 
Sbjct: 566 TVIKLPDESF-RMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGL 624

Query: 681 RVVALASKPLPTVPSLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIR 740
           R + +A +  P+ P  +   +   + +  +L+ + ++ + + ++P+    I+  +R  I 
Sbjct: 625 RTICVAYRDFPSSPEPDWDNE---NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 681

Query: 741 AVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHA---THPERGQPASLEFLPMESPTAVNG 797
             MVTGDN+ TA  +A  CG++ P E  + +         R +   +E   ++       
Sbjct: 682 VRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERID------- 734

Query: 798 VKVLVQGTVFARMAPEQKTELVCEL-----QKLQYCVGMCGDGANDCGALKAADVGISLS 852
            K+  +  V AR +P  K  LV  +      + +  V + GDG ND  ALK ADVG ++ 
Sbjct: 735 -KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMG 793

Query: 853 QAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILY---- 908
            A   V    +  + + +    +++      +   S+ K++        ++V++ +    
Sbjct: 794 IAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 853

Query: 909 -TINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVL 967
            T ++ L  +Q L ++L++ T  ++ ++   P   L   +P G   + P++S  +++ +L
Sbjct: 854 ITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGR--NKPLISRTMMKNIL 911



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 7/96 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   +  +E+V GD +  
Sbjct: 162 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVVR-AGQVVQIPVAEIVVGD-IAQ 215

Query: 316 PQEGGLMPCDAALVAG-ECMVNESSLTGESIPVLKT 350
            + G L+P D   + G +  ++ESSLTGES  V K+
Sbjct: 216 VKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS 251


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
            sapiens]
          Length = 1220

 Score =  100 bits (250), Expect = 6e-21
 Identities = 129/590 (21%), Positives = 242/590 (41%), Gaps = 69/590 (11%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 419  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V    G      +P P  L    +L  L    +++    T +  P      
Sbjct: 479  TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630
                   E+E A     G +    +   + + +   Q + E  +P   L++ + F+S  +
Sbjct: 530  -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677
             MS V+  P       + KG+ E++   C              P        ++++    
Sbjct: 582  SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640

Query: 678  AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G R + +A +         A Q+   D    V GDL+ + ++ + + ++P+    I+  
Sbjct: 641  DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHA---THPERGQPASLEFLPMES 791
            +R  I   MVTGDN+ TA  +A  CG++ P E  + +         R +   +E   ++ 
Sbjct: 695  QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLD- 753

Query: 792  PTAVNGVKVLVQGTVFARMAPEQKTELV-----CELQKLQYCVGMCGDGANDCGALKAAD 846
                   KV  +  V AR +P  K  LV         + +  V + GDG ND  ALK AD
Sbjct: 754  -------KVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKAD 806

Query: 847  VGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI 906
            VG ++  A   V    +  + + +    +++      +   S+ K++        ++V++
Sbjct: 807  VGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 866

Query: 907  LY-----TINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSL 961
             +     T ++ L  +Q L ++L++ T  ++ ++   P   L   +P G     P++S  
Sbjct: 867  AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGR--DKPLISRT 924

Query: 962  LLQMVLVTGV-QLGGYF-LTLAQPWFVPLNRTVAAPDNLPNYEN-TVVFS 1008
            +++ +L   V QL   F L      F  ++    AP + P  E+ T++F+
Sbjct: 925  MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFN 974



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   V  + LV GD +  
Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218

Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351
            + G L+P D  L+ A +  ++ESSLTGES  V K+A
Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
            sapiens]
          Length = 1173

 Score =  100 bits (250), Expect = 6e-21
 Identities = 129/590 (21%), Positives = 242/590 (41%), Gaps = 69/590 (11%)

Query: 454  IRALDLVTVVVPPALPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTL 513
            I  + ++ V VP  LP A+T+   Y+  ++ +      H       G    +C DKTGTL
Sbjct: 419  IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 478

Query: 514  TEDGLDVMGVVPLKGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMV 573
            T + + V  V    G      +P P  L    +L  L    +++    T +  P      
Sbjct: 479  TTNRMTV--VQSYLGDTHYKEIPAPSAL-TPKILDLLVHAISINSAYTTKILPP------ 529

Query: 574  ESTGWVLEEEPAADSAFGTQVLAVMRPPLWEPQ--LQAMEEPPVPVSVLHR-FPFSSALQ 630
                   E+E A     G +    +   + + +   Q + E  +P   L++ + F+S  +
Sbjct: 530  -------EKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ-IPEDKLYKVYTFNSVRK 581

Query: 631  RMSVVVAWPGATQPEAYVKGSPELVAGLCN-------------PETVPTDFAQMLQSYTA 677
             MS V+  P       + KG+ E++   C              P        ++++    
Sbjct: 582  SMSTVIRMPDGGF-RLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMAC 640

Query: 678  AGYRVVALASKPLPTVPSLEAAQQLTRDT---VEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
             G R + +A +         A Q+   D    V GDL+ + ++ + + ++P+    I+  
Sbjct: 641  DGLRTICIAYR------DFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKC 694

Query: 735  RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHA---THPERGQPASLEFLPMES 791
            +R  I   MVTGDN+ TA  +A  CG++ P E  + +         R +   +E   ++ 
Sbjct: 695  QRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLD- 753

Query: 792  PTAVNGVKVLVQGTVFARMAPEQKTELV-----CELQKLQYCVGMCGDGANDCGALKAAD 846
                   KV  +  V AR +P  K  LV         + +  V + GDG ND  ALK AD
Sbjct: 754  -------KVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKAD 806

Query: 847  VGISLSQAEASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLI 906
            VG ++  A   V    +  + + +    +++      +   S+ K++        ++V++
Sbjct: 807  VGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 866

Query: 907  LY-----TINTNLGDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSL 961
             +     T ++ L  +Q L ++L++ T  ++ ++   P   L   +P G     P++S  
Sbjct: 867  AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGR--DKPLISRT 924

Query: 962  LLQMVLVTGV-QLGGYF-LTLAQPWFVPLNRTVAAPDNLPNYEN-TVVFS 1008
            +++ +L   V QL   F L      F  ++    AP + P  E+ T++F+
Sbjct: 925  MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFN 974



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 256 LCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVPGDCLVL 315
           +C+ L+++ +     +   KQ + L+  ++   +  V R  G+   V  + LV GD +  
Sbjct: 165 ICVVLVTAFND----WSKEKQFRGLQSRIEQEQKFTVIR-NGQLLQVPVAALVVGD-IAQ 218

Query: 316 PQEGGLMPCDAALV-AGECMVNESSLTGESIPVLKTA 351
            + G L+P D  L+ A +  ++ESSLTGES  V K+A
Sbjct: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSA 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,458,223
Number of Sequences: 37866
Number of extensions: 2685173
Number of successful extensions: 23779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 563
Number of HSP's that attempted gapping in prelim test: 14853
Number of HSP's gapped (non-prelim): 5357
length of query: 1158
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1045
effective length of database: 13,968,660
effective search space: 14597249700
effective search space used: 14597249700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press