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Search of human proteins with 21389569
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389569 tektin 5 [Homo sapiens]
(485 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389569 tektin 5 [Homo sapiens] 988 0.0
gi|13994250 tektin 3 [Homo sapiens] 455 e-128
gi|16753231 tektin 1 [Homo sapiens] 260 2e-69
gi|21389613 tektin 4 [Homo sapiens] 228 9e-60
gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] 192 7e-49
gi|16507950 tektin 2 [Homo sapiens] 164 2e-40
gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] 125 7e-29
gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] 77 5e-14
gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] 55 2e-07
gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] 54 3e-07
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 54 4e-07
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 54 4e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 47 3e-05
gi|58530840 desmoplakin isoform I [Homo sapiens] 46 7e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 1e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 43 6e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 42 0.001
gi|55770834 centromere protein F [Homo sapiens] 41 0.003
gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens] 41 0.003
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 40 0.006
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 39 0.011
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 39 0.011
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 39 0.011
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 39 0.014
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 39 0.014
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 39 0.014
gi|156104908 myosin heavy chain 6 [Homo sapiens] 38 0.018
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 38 0.018
gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens] 38 0.024
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 38 0.024
>gi|21389569 tektin 5 [Homo sapiens]
Length = 485
Score = 988 bits (2554), Expect = 0.0
Identities = 485/485 (100%), Positives = 485/485 (100%)
Query: 1 MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKIAN 60
MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKIAN
Sbjct: 1 MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKIAN 60
Query: 61 VQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSM 120
VQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSM
Sbjct: 61 VQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSM 120
Query: 121 RLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAA 180
RLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAA
Sbjct: 121 RLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAA 180
Query: 181 NEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMR 240
NEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMR
Sbjct: 181 NEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMR 240
Query: 241 DNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSN 300
DNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSN
Sbjct: 241 DNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSN 300
Query: 301 DNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQL 360
DNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQL
Sbjct: 301 DNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQL 360
Query: 361 AKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVF 420
AKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVF
Sbjct: 361 AKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVF 420
Query: 421 TIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPR 480
TIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPR
Sbjct: 421 TIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPR 480
Query: 481 LVGHT 485
LVGHT
Sbjct: 481 LVGHT 485
>gi|13994250 tektin 3 [Homo sapiens]
Length = 490
Score = 455 bits (1170), Expect = e-128
Identities = 246/492 (50%), Positives = 333/492 (67%), Gaps = 13/492 (2%)
Query: 1 MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNS----WRPSLFY 56
ME +G T T +Y P+ LPA+ + Y+ + P +S WRPS +Y
Sbjct: 1 MERVGCTLTTTYAHPRPT-PTNFLPAIST--MASSYRDRF-PHSNLTHSLSLPWRPSTYY 56
Query: 57 KIA-NVQTCPDESTSTLRPP--TILPTL--RSALFSRYSPHDWDQSNQLQVRGAEASRLW 111
K+A N + T + R T+LP + R+ F+RY+P DW +SN + + SR
Sbjct: 57 KVASNSPSVAPYCTRSQRVSENTMLPFVSNRTTFFTRYTPDDWYRSNLTNYQESNTSRHN 116
Query: 112 ASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLET 171
+ +L D+ RL+QDK Q T + Q T +NLG+R++DIGFWKSE+ +ELD ++ E L
Sbjct: 117 SEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTD 176
Query: 172 VKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKL 231
VK+RLE A E PLQVA ECL+HREKR+GIDLVHD VE L+ EVD + CCQE+M+
Sbjct: 177 VKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLH 236
Query: 232 AQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISV 291
+ Q+ NR +QH LE+DL DK +A ID+KC +LRNTSD + +F G+E++D T+SV
Sbjct: 237 LDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSV 296
Query: 292 PETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTD 351
PE+WAKF++DNI SQ+ RA S +LR++ E+L +++MW QF NL+F RI+E D
Sbjct: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356
Query: 352 VKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIP 411
KNK+QT LAKTLQEIFQ E TI ++++I K LKVAQTRL+ RTRRPN+ELCRD+
Sbjct: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMA 416
Query: 412 QLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGM 471
QL+LVNEV +DDT+QTL+ RLR+ +DTLQ LV K LE++LA+KAN+L ID+EKCM M
Sbjct: 417 QLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSM 476
Query: 472 RKTFPCTPRLVG 483
RK++P T RLVG
Sbjct: 477 RKSYPNTLRLVG 488
>gi|16753231 tektin 1 [Homo sapiens]
Length = 418
Score = 260 bits (665), Expect = 2e-69
Identities = 142/389 (36%), Positives = 221/389 (56%)
Query: 88 RYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSD 147
++ P +W +N+ Q A+A R + RL +S RL+ + ++ T + Q + L QRL +
Sbjct: 10 KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69
Query: 148 IGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVH 207
+ FWK EL +L++L+ +L K RLE A + PL + CL +REKRIGIDLVH
Sbjct: 70 VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129
Query: 208 DNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
D VE LI+E ++++ + + + Q+R NR A++ LE+DL+DK A ID+ CF
Sbjct: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189
Query: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETL 327
+L N S I + +I+ E W FS+ N++ + R NS+ L+ + +
Sbjct: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249
Query: 328 SDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGP 387
++ + +Q + AF + + D ++KL LAK ++EI E I LE++I+ +EGP
Sbjct: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309
Query: 388 LKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTK 447
KVA TRLE RT RPN+ELCRD+ Q +L+ EV I + LK L + Q L+ L +
Sbjct: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369
Query: 448 CRLEHELAIKANTLCIDKEKCMGMRKTFP 476
L+ E+ +K NT+ ID+ CM MRK+ P
Sbjct: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398
>gi|21389613 tektin 4 [Homo sapiens]
Length = 435
Score = 228 bits (581), Expect = 9e-60
Identities = 138/398 (34%), Positives = 210/398 (52%)
Query: 87 SRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLS 146
S+Y +W Q+ + A A R + R +S +L + L + Q+ + R +G+RL
Sbjct: 37 SKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQ 96
Query: 147 DIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLV 206
D WKSEL E++ L E L K+RLE A + P + + L RE+R +LV
Sbjct: 97 DTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLV 156
Query: 207 HDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKC 266
D+VE L++E +L++ QE +++ + Q+R NR+ + E D DK A IDE C
Sbjct: 157 RDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETC 216
Query: 267 FNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFET 326
+ S + + S PET AKF+ DN+ +Q R S LR + +
Sbjct: 217 GRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRD 276
Query: 327 LSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEG 386
S+ + Q NLAF R E+ D + KL L KTL+EI E+ + L+++I KE
Sbjct: 277 TSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEA 336
Query: 387 PLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMT 446
PL VAQTRL R+ RPNMELCRD Q +L++EV ++ +L L+ +L E + +L+ L
Sbjct: 337 PLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDI 396
Query: 447 KCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGH 484
LE ++A N+L ID++KCM R +P +L G+
Sbjct: 397 HMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434
>gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 445
Score = 192 bits (487), Expect = 7e-49
Identities = 115/355 (32%), Positives = 189/355 (53%), Gaps = 5/355 (1%)
Query: 134 QEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALEC 193
Q+ TCR +G+RL D WKSEL E++ L E L K+RLE A + + P + +
Sbjct: 91 QDSTCR-VGERLQDTNSWKSELQREVEALAAETDLLLAQKQRLERALDAMEVPFSITTDN 149
Query: 194 LYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDL 253
+ ++ +L+ D+VE L++E +L++ QE +++ + Q+ N + + E D
Sbjct: 150 MQCSQRHQHTNLLRDHVETELLKEAELIRNIQELLKRAIMQAVSQIXLNXEHMEICEMDW 209
Query: 254 EDKSSAQCIDEKCFNLRNTSDCISFF-HG---MEKIDGTISVPETWAKFSNDNIKHSQNM 309
DK A +D+ C + S + H E+ + S PET KF+ DN+ H+Q
Sbjct: 210 SDKVEAYNLDKTCGRHHSQSTEVQAHPHSTTFQERGPRSASTPETRTKFTQDNLCHAQRE 269
Query: 310 RANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQ 369
R +S L + + S+ + Q NLAF R E+ D ++KLQ L K L+EI
Sbjct: 270 RLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLHKMLREITD 329
Query: 370 AENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTL 429
E+ ++ L+ +I KE PL +AQTRL + RPNM+LCRD Q +LV+EV + ++ L
Sbjct: 330 QEHNVVALKEAIKDKEEPLHIAQTRLXLLSHRPNMQLCRDAAQFRLVSEVEELYKSITAL 389
Query: 430 KLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGH 484
+ +L + + +L+ L LE ++ N++ ID++KCM R +P +L G+
Sbjct: 390 REKLLQAEQSLRNLKDIHMSLEKDVTAMTNSVFIDRQKCMAHRTCYPTILQLAGY 444
>gi|16507950 tektin 2 [Homo sapiens]
Length = 430
Score = 164 bits (414), Expect = 2e-40
Identities = 114/386 (29%), Positives = 184/386 (47%), Gaps = 1/386 (0%)
Query: 88 RYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSD 147
R+ DW ++ L A+ R + ++ ++ L + + T + L +R+
Sbjct: 11 RFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDT 70
Query: 148 IGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVH 207
+ WK L L L E L +K E N PL VA+ECL RE R ID+V
Sbjct: 71 VNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVK 130
Query: 208 DNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
D VE L +EV++++ ++ +++ + Q+ ++ Q L D K ID C
Sbjct: 131 DPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKMETLEIDRGCL 190
Query: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETL 327
+L S IS ++ + + W FS N ++ + +LRE
Sbjct: 191 SLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELREATALTIAET 250
Query: 328 SDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGP 387
++++ Q T AF R+ E+ V ++L+ Q TL+EI + + I LE + K
Sbjct: 251 NNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLS 310
Query: 388 LKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTK 447
LK++ TRLE RT RPN+ELCRD Q L +EV ++ T+ LK +L + QD L L
Sbjct: 311 LKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALCKHL 370
Query: 448 CRLEHELAIKANTLCIDKEKCMGMRK 473
RL+ ++A KAN++ +D KCM R+
Sbjct: 371 ARLQADIACKANSMLLD-TKCMDTRR 395
>gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 507
Score = 125 bits (315), Expect = 7e-29
Identities = 116/457 (25%), Positives = 181/457 (39%), Gaps = 117/457 (25%)
Query: 134 QEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLE-----------CAANE 182
Q+ CR +G+RL D+ W SEL E++ L E L K+RLE A +
Sbjct: 61 QDSKCR-VGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDN 119
Query: 183 VNC-------------------------PLQVALECLYHREKRIGIDLVHDNVEKNLIRE 217
+ C P Q C R+ V + +E ++E
Sbjct: 120 MQCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQE 179
Query: 218 -------------------VDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSS 258
+L++ QE ++++ + Q+R NR+ + E D DK
Sbjct: 180 EANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVE 239
Query: 259 AQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLRE 318
A +DE C R+ S + S PET KF+ DN+ +Q R +S L
Sbjct: 240 AYNLDETCGRHRSQST----------EPRSASTPETRTKFTQDNLCRAQRERLDSANLWV 289
Query: 319 EAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLE 378
+ + S+ + Q NLAF R E+ D ++KLQ L K L+EI E+ ++ L+
Sbjct: 290 LVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALK 349
Query: 379 RSIMAKEGPLKVAQTRLECRTRRPNMELCRDI---------------------------- 410
+I KE PL +AQTRL + RPNMELCRD
Sbjct: 350 EAIKDKEAPLHIAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGL 409
Query: 411 -----------------PQL------KLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTK 447
PQL KLV+E+ + ++ L +L + + +L L
Sbjct: 410 TPPSATSSSQEEAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIH 469
Query: 448 CRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGH 484
LE ++ N+L +D++ CM +P +L G+
Sbjct: 470 MSLEKDVTAMTNSLFLDRQNCMAHHTCYPTILQLAGY 506
>gi|75677606 hypothetical protein LOC100132288 [Homo sapiens]
Length = 129
Score = 76.6 bits (187), Expect = 5e-14
Identities = 42/106 (39%), Positives = 60/106 (56%)
Query: 290 SVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEV 349
S PET KF+ DN+ H+Q R +S L + + S+ + Q NLAF R E+
Sbjct: 24 STPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCRCEEL 83
Query: 350 TDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRL 395
D ++KLQ L K L+EI E+ ++ L+ +I KE PL +AQTRL
Sbjct: 84 EDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129
>gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]
Length = 254
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/99 (30%), Positives = 50/99 (50%)
Query: 118 DSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLE 177
+S +L + L Q+ + R +G++L D WKSEL E++ L E L K+RLE
Sbjct: 43 ESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLE 102
Query: 178 CAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIR 216
A + P +A + L + +L+ D+VE L++
Sbjct: 103 HALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLK 141
Score = 31.6 bits (70), Expect = 1.7
Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 17/124 (13%)
Query: 298 FSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQ 357
F+N N + S QL E + L + R+ + ++ + K++LQ
Sbjct: 29 FANCNQSERELQGHESQQLAAETQALAQGTQQDSTRRVGE-------QLQDTHSWKSELQ 81
Query: 358 TQLAKTLQEIFQAENTIML-----LERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQ 412
++ E AE ++L LE ++ A E P +A L+C N L RD +
Sbjct: 82 REV-----EALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVE 136
Query: 413 LKLV 416
+L+
Sbjct: 137 TELL 140
>gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens]
Length = 333
Score = 53.9 bits (128), Expect = 3e-07
Identities = 30/99 (30%), Positives = 50/99 (50%)
Query: 118 DSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLE 177
+S +L + L Q+ + R +G++L D WKSEL E++ L E L K+RLE
Sbjct: 59 ESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLE 118
Query: 178 CAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIR 216
A + P +A + L + +L+ D+VE L++
Sbjct: 119 HALDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLK 157
Score = 30.0 bits (66), Expect = 4.9
Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 17/124 (13%)
Query: 298 FSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQ 357
F+N N + S QL E + L + R+ + ++ + K++LQ
Sbjct: 45 FANCNQSEQELQGHESQQLAAETQALAQGTQQDSTRRVGE-------QLQDTHSWKSELQ 97
Query: 358 TQLAKTLQEIFQAENTIML-----LERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQ 412
++ E AE ++L LE ++ A E P +A L+C + L RD +
Sbjct: 98 REV-----EALAAETDLLLAQKQRLEHALDATEAPFSIATDNLQCSQGHQHANLMRDHVE 152
Query: 413 LKLV 416
+L+
Sbjct: 153 TELL 156
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 53.5 bits (127), Expect = 4e-07
Identities = 74/334 (22%), Positives = 145/334 (43%), Gaps = 38/334 (11%)
Query: 154 ELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKN 213
ELS EL L + +N + KR+L+ E + + L+ + H+ + G + +E++
Sbjct: 406 ELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQG--SIKCKLEED 463
Query: 214 LIREVDLLKCCQEQMRKLAQRIDIQMRDNRDA--QHVLERDLEDKSSAQCIDEKCFNLRN 271
L LL+ +EQ++K + + M +A Q ++D K +++ ++E+ NLR
Sbjct: 464 LQEATKLLEDKREQLKKSKEHEKL-MEGELEALRQEFKKKDKTLKENSRKLEEENENLRA 522
Query: 272 TSDCISFFHGMEKIDGTISVPETWAKFSNDNIKH--SQNMRANSIQ------LREEAEHL 323
C S +++ +++ T + D K Q S+Q L++E +L
Sbjct: 523 ELQCCS-----TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYL 577
Query: 324 FETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMA 383
T++ + + + + A +++ + N + ++ Q + Q + LE I+A
Sbjct: 578 QTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIA 637
Query: 384 KEGPLKVAQTRL-ECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRL----RETQD 438
E +K T L + R EL EV D L+ + ++ ++ Q+
Sbjct: 638 YEERMKKLNTELRKLRGFHQESEL-----------EVHAFDKKLEEMSCQVLQWQKQHQN 686
Query: 439 TLQLLVMTKCRL----EHELAIKANTLCIDKEKC 468
L++L + +L E A+K N L DKE C
Sbjct: 687 DLKMLAAKEEQLREFQEEMAALKENLLEDDKEPC 720
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 53.5 bits (127), Expect = 4e-07
Identities = 74/334 (22%), Positives = 145/334 (43%), Gaps = 38/334 (11%)
Query: 154 ELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKN 213
ELS EL L + +N + KR+L+ E + + L+ + H+ + G + +E++
Sbjct: 551 ELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQG--SIKCKLEED 608
Query: 214 LIREVDLLKCCQEQMRKLAQRIDIQMRDNRDA--QHVLERDLEDKSSAQCIDEKCFNLRN 271
L LL+ +EQ++K + + M +A Q ++D K +++ ++E+ NLR
Sbjct: 609 LQEATKLLEDKREQLKKSKEHEKL-MEGELEALRQEFKKKDKTLKENSRKLEEENENLRA 667
Query: 272 TSDCISFFHGMEKIDGTISVPETWAKFSNDNIKH--SQNMRANSIQ------LREEAEHL 323
C S +++ +++ T + D K Q S+Q L++E +L
Sbjct: 668 ELQCCS-----TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYL 722
Query: 324 FETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMA 383
T++ + + + + A +++ + N + ++ Q + Q + LE I+A
Sbjct: 723 QTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIA 782
Query: 384 KEGPLKVAQTRL-ECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRL----RETQD 438
E +K T L + R EL EV D L+ + ++ ++ Q+
Sbjct: 783 YEERMKKLNTELRKLRGFHQESEL-----------EVHAFDKKLEEMSCQVLQWQKQHQN 831
Query: 439 TLQLLVMTKCRL----EHELAIKANTLCIDKEKC 468
L++L + +L E A+K N L DKE C
Sbjct: 832 DLKMLAAKEEQLREFQEEMAALKENLLEDDKEPC 865
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 47.4 bits (111), Expect = 3e-05
Identities = 76/361 (21%), Positives = 158/361 (43%), Gaps = 44/361 (12%)
Query: 99 QLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQE------GTCRNLGQRLSDIGFWK 152
+ + R E L +R +++M + ++L Q + + ++G+ + ++ K
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 153 SELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEK 212
L +++ + T+ + LE + E A + LQ A++ + R+ + G D + +K
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ-AMKAQFERDLQ-GRDEQSEEKKK 1585
Query: 213 NLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLED-----KSSAQCIDEKCF 267
L+R+V ++ E RK Q A+ LE DL+D S+ + DE
Sbjct: 1586 QLVRQVREMEAELEDERK-------QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIK 1638
Query: 268 NLRNTS----DCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREE--AE 321
LR DC M ++D T + E + +N K ++M A IQL+EE A
Sbjct: 1639 QLRKLQAQMKDC------MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAA 1692
Query: 322 HLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAE-NTIMLLERS 380
+ + Q + D + + + + K +L+ ++A+ +E+ + + NT ++ +R
Sbjct: 1693 ERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR- 1751
Query: 381 IMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTL 440
K+ L++ Q + R + + K N ++ + LK++L+E + T+
Sbjct: 1752 --LKKANLQIDQINTDLNLERSHAQ--------KNENARQQLERQNKELKVKLQEMEGTV 1801
Query: 441 Q 441
+
Sbjct: 1802 K 1802
Score = 29.6 bits (65), Expect = 6.4
Identities = 35/178 (19%), Positives = 68/178 (38%), Gaps = 26/178 (14%)
Query: 302 NIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLA 361
N+ + + +L+ + E + L +++ R+ + E+ + KL+
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE--------EKQRQELEKTRRKLEGDST 1058
Query: 362 KTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNM------ELCRDIPQL-- 413
+I + + I L+ + KE L+ A R+E + NM EL I +L
Sbjct: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
Query: 414 ----------KLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTL 461
K + + + L+ LK L +T D+ + + E E+ I TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 46.2 bits (108), Expect = 7e-05
Identities = 79/339 (23%), Positives = 144/339 (42%), Gaps = 34/339 (10%)
Query: 125 DKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVN 184
D DQL + ++ NLG + + E YE++RL Q T KR E +V
Sbjct: 1138 DYDQL-QKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVR 1196
Query: 185 CPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRD 244
+ L ++ + N+ K I+E+ + K ++ + L ++D R+NRD
Sbjct: 1197 NHYNEEMSNLRNKYE------TEINITKTTIKEISMQK--EDDSKNLRNQLDRLSRENRD 1248
Query: 245 AQHVLERDLEDKSSAQCIDEKCF---NLRNTSDCISFFHGMEKIDGTISVPETWAKFSND 301
+ + R L D S Q +++ N C S +K I + + + S D
Sbjct: 1249 LKDEIVR-LND-SILQATEQRRRAEENALQQKACGSEIM-QKKQHLEIELKQVMQQRSED 1305
Query: 302 NIKHSQNMR--ANSIQLR-EEAEHL---FETLSDQMWRQFTDTNLAFNARISEVTDVKNK 355
N +H Q++ A +IQ + +E E L F+ + + W + + N E+ +KN+
Sbjct: 1306 NARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQ 1365
Query: 356 LQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKL 415
+T++ T I Q M KE + +++ TR N L +I +LK
Sbjct: 1366 FETEINITKTTIHQL----------TMQKEEDTSGYRAQIDNLTRE-NRSLSEEIKRLK- 1413
Query: 416 VNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHEL 454
N + + L+ ++ +++ + T + K +LE EL
Sbjct: 1414 -NTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVEL 1451
Score = 29.3 bits (64), Expect = 8.4
Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 15/143 (10%)
Query: 119 SMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLET---VKRR 175
S R+ + K+Q T +QE +L ++ + K+ L D L LE VK+R
Sbjct: 1795 SNRIQESKNQCTQVVQER--ESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQR 1852
Query: 176 LECAANEVNCPLQVALECLYHRE----KRIGIDLVHDNVEKNLIR-EVDLLKCCQEQMRK 230
LEC ++ L + Y R+ ++I + EKN +R E++ L Q ++++
Sbjct: 1853 LECEKQQIQNDLN-QWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERL---QAEIKR 1908
Query: 231 LAQRIDIQMRDN-RDAQHVLERD 252
+ +R ++ D+ R+ Q LE +
Sbjct: 1909 IEERCRRKLEDSTRETQSQLETE 1931
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.4 bits (106), Expect = 1e-04
Identities = 63/324 (19%), Positives = 123/324 (37%), Gaps = 51/324 (15%)
Query: 154 ELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKN 213
EL+ + +TE Q ++ K L + V L + L + + +K
Sbjct: 829 ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEF-----EKENQKG 883
Query: 214 LIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLED----KSSAQCIDEKCFNL 269
+DL K C+E +L +++ +++ ++ + LE++ E K + E+
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 270 RNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSD 329
+NT N K Q ++ N +L++ +E
Sbjct: 944 QNTL--------------------------KQNEKEEQQLQGNINELKQSSE-------- 969
Query: 330 QMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLK 389
Q +Q + + T+++NKLQ QL + QE+ + I +L+ + + K
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK 1029
Query: 390 VAQTRLECRTRRPNMELCRDIPQLKLVNEVFTI-DDTLQTLKLRLRETQDTLQLLVMTKC 448
Q+ R EL LK V E ++ + L + + ++ +Q L K
Sbjct: 1030 QLQSDFYGR----ESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085
Query: 449 RLEHELAIKANTLCIDKEKCMGMR 472
LE + A K L +E+C ++
Sbjct: 1086 TLEQDSAKKEQQL---QERCKALQ 1106
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 43.1 bits (100), Expect = 6e-04
Identities = 99/460 (21%), Positives = 184/460 (40%), Gaps = 76/460 (16%)
Query: 40 YLPGYRYLNSWRPSLFYKIANVQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQ 99
Y RYL+S P+ D TS+ ++ +L+ ++ + N+
Sbjct: 399 YYSNRRYLSSANPN------------DNRTSSNADKSLQESLQKTIYKL----EEQLHNE 442
Query: 100 LQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYEL 159
+Q++ + S + D +++++ D+ +Q RNL +S I K L + +
Sbjct: 443 MQLKDEMEQKCRTSNIKLD--KIMKELDEEGNQR-----RNLESTVSQIEKEKMLLQHRI 495
Query: 160 D------------RLLTENQNLETVKRRLECA---------ANEVNCPLQVALE---CLY 195
+ R EN+ + T+K +LE ANE LQ LE L
Sbjct: 496 NEYQRKAEQENEKRRNVENE-VSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLL 554
Query: 196 HREKRIGIDL--VHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDL 253
E + L H + K++ + L + QE+ R L +D Q +LE +
Sbjct: 555 RTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAER 614
Query: 254 EDKS-SAQCIDEKCFNLRNTSDCISFF-HGMEKIDGTISVPETWAKFSNDNIKHSQNMRA 311
D+ ++ I + + + + + H +EK++G K + D + HS+ +
Sbjct: 615 RDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGE-------RKEAQDMLNHSEKEKN 667
Query: 312 N-SIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQA 370
N I L + + L + L ++ + T + + + K+ ++ K L+E +A
Sbjct: 668 NLEIDLNYKLKSLQQRLEQEV-NEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREA 726
Query: 371 ----ENTIMLLERSIMAKEGPLKVAQTRLECRT-RRPNME-----LCRDIPQ-----LKL 415
EN ++ +E+ + LK +Q +LE T + ME L + Q L L
Sbjct: 727 REKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786
Query: 416 VNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELA 455
NE+ T LK ++ + + L+ K LE ELA
Sbjct: 787 QNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELA 826
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 42.0 bits (97), Expect = 0.001
Identities = 69/324 (21%), Positives = 133/324 (41%), Gaps = 41/324 (12%)
Query: 93 DWDQSNQLQVRGAEASRLWASRLTDDSMRLL----QDKDQLTHQMQEGTCRNLGQRLSDI 148
+W Q + EAS+ + L+ + ++ + DQL +E +NL Q +SD+
Sbjct: 1458 EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN--KNLQQEISDL 1515
Query: 149 GFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRI-----GI 203
+E ++ LE +K+++E E+ L+ A L H E +I +
Sbjct: 1516 TEQIAEGGKQI-------HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 204 DLVHDNVEKNLI---REVDLLKCCQEQMRKLAQ-RIDIQMRDNRDAQHV---LERDLED- 255
+ V V++ + E+D LK ++ + Q +D ++R DA V +E DL +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 256 ----KSSAQCIDEKCFNLRNTSDCI--------SFFHGMEKIDGTISVPETWAKFSNDNI 303
+ + E N RNT + G E + +++ E A I
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 304 KHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKT 363
+ + + R+ AE S+++ T N + DV ++LQ+++ +
Sbjct: 1689 EELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDV-SQLQSEVEEV 1747
Query: 364 LQEIFQAENTI--MLLERSIMAKE 385
+QE AE + + ++MA+E
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEE 1771
Score = 33.1 bits (74), Expect = 0.58
Identities = 50/258 (19%), Positives = 115/258 (44%), Gaps = 34/258 (13%)
Query: 198 EKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQ---RIDIQMRDNRD-AQHVLERDL 253
EK + + ++++ + E D L +E+ +L + +++ ++++ + A+ E +
Sbjct: 878 EKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINA 937
Query: 254 EDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANS 313
E + + ++++C L+ D + T AK + KH+ + +
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLEL---------------TLAKVEKE--KHATENKVKN 980
Query: 314 IQLREEAEHLFETLS---------DQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTL 364
L EE L ET++ + +Q D A +++ +T K KL+ Q+
Sbjct: 981 --LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLE 1038
Query: 365 QEIFQAENTIMLLERSIMAKEGPLKVAQ-TRLECRTRRPNMELCRDIPQLKLVNEVFTID 423
+ Q + M LER+ EG LK+AQ + ++ + ++ + + ++ N + I+
Sbjct: 1039 GSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIE 1098
Query: 424 DTLQTLKLRLRETQDTLQ 441
D Q ++++L++ LQ
Sbjct: 1099 DE-QAVEIQLQKKIKELQ 1115
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.8 bits (94), Expect = 0.003
Identities = 82/405 (20%), Positives = 169/405 (41%), Gaps = 66/405 (16%)
Query: 97 SNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGT---CRNLGQRLSDIGFWKS 153
+ Q+Q + + S L +L LL++K+Q Q++E + L +L ++ +
Sbjct: 2216 TKQIQEKQGQLSEL--DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2273
Query: 154 ELSYELDRLLTENQNL--------------ETVKRRLECAANEVNCPLQVALECLYHREK 199
L + + + Q+L E ++ RLE + C LQ E +H
Sbjct: 2274 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHA-- 2331
Query: 200 RIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKS-S 258
DL+ VE NL RE+++ + QE ++ +++ L+ +E + S
Sbjct: 2332 ----DLLKGRVE-NLERELEIARTNQEHAA-------LEAENSKGEVETLKAKIEGMTQS 2379
Query: 259 AQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLRE 318
+ ++ +R+ + ++ + ++K IS E S +NI Q +Q++E
Sbjct: 2380 LRGLELDVVTIRSEKENLT--NELQKEQERISELEI-INSSFENIL--QEKEQEKVQMKE 2434
Query: 319 EAEHLFETLSDQMWR------QFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAEN 372
++ E L Q+ + A A+ ++ L+ + A+ LQ + +A+N
Sbjct: 2435 KSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKN 2494
Query: 373 TIMLLERSIMAKEGPLKVAQTRLECR----TRRPNM-----ELCRDIPQ----------- 412
++L+ S+ ++ + +LE + +R N +L + Q
Sbjct: 2495 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQ 2554
Query: 413 -LKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAI 456
L+L N ++ +Q L+ + QDTL++L + LE+EL +
Sbjct: 2555 NLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELEL 2599
Score = 29.3 bits (64), Expect = 8.4
Identities = 52/229 (22%), Positives = 90/229 (39%), Gaps = 35/229 (15%)
Query: 78 LPTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMR-----LLQDKDQLTHQ 132
L T++ AL S + + Q+N G + + + M+ LLQ+ +QL
Sbjct: 1103 LETVQQALRSEMTDN---QNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKV 1159
Query: 133 MQ-EGTCRNLG---------QRLSDIGF--WKSELSYELDRLLTENQNLETVKRRLECAA 180
M+ + C+NL +R S+ +K ++ E+ + ++ N + V+ LE
Sbjct: 1160 MKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQ--LEAML 1217
Query: 181 NEVNCPLQVA---LECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDI 237
LQ + ECL H + I DL N++ +E+ LK C+ ID
Sbjct: 1218 RNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCE---------IDA 1268
Query: 238 QMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKID 286
+ + H L D + QC + N N + I EK +
Sbjct: 1269 EEK-YISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYE 1316
>gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens]
Length = 670
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/190 (24%), Positives = 85/190 (44%), Gaps = 29/190 (15%)
Query: 79 PTLRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLL-QDKDQLTHQMQEGT 137
P ++ +Y+ QS + E W + L + + ++ Q +D + H++
Sbjct: 88 PVVKEKEKKKYNVSKISQSKGQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRI---- 143
Query: 138 CRNLGQRLSDIGFWKSELS---YELDRLLTENQNLETVK-RRLECAANEVNCPLQVALEC 193
L RL I K+EL+ ++L+ +LTENQ L+ ++ R L+ N
Sbjct: 144 ---LSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYEN--------- 191
Query: 194 LYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRI---DIQMRDNRDAQHVLE 250
+ I H N KNL + LL+ QE+ R L++++ D Q+ +D L+
Sbjct: 192 --SQNNLPQIMAKHQNEVKNLRQ---LLRKSQEKERTLSRKLRETDSQLLKTKDILQALQ 246
Query: 251 RDLEDKSSAQ 260
+ EDK+ A+
Sbjct: 247 KLSEDKNLAE 256
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 39.7 bits (91), Expect = 0.006
Identities = 82/384 (21%), Positives = 160/384 (41%), Gaps = 46/384 (11%)
Query: 93 DWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQ--EGTCRNLGQRLSDIGF 150
+W Q + EAS+ + L+ + ++ ++ ++ + +NL Q +SD+
Sbjct: 1459 EWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL-- 1516
Query: 151 WKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHRE-KRIGIDLVHDN 209
+E E + + E LE VK++L+ +E+ L+ A L H E K + I L +
Sbjct: 1517 --TEQIAEGGKHIHE---LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQ 1571
Query: 210 VEKNLIR-------EVDLLKCCQ-EQMRKLAQRIDIQMRDNRDAQHV---LERDLED--- 255
V+ + R E+D LK + + +D ++R DA + +E DL +
Sbjct: 1572 VKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEI 1631
Query: 256 --KSSAQCIDEKCFNLRNTSDCI--------SFFHGMEKIDGTISVPETWAKFSNDNIKH 305
+ + E NLRNT + G + + +++ E A ++
Sbjct: 1632 QLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEE 1691
Query: 306 SQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQ 365
+ + + R+ AE S+++ T N + TD+ +++Q ++ +Q
Sbjct: 1692 LRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDI-SQIQGEMEDIVQ 1750
Query: 366 EIFQAENTI--MLLERSIMAKEGPLKVAQ-TRLECRTRRPNMELCRDIPQLKLVNEVFTI 422
E AE + + ++MA+E LK Q T + NME QL+L +E +
Sbjct: 1751 EARNAEEKAKKAITDAAMMAEE--LKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQL 1807
Query: 423 -----DDTLQTLKLRLRETQDTLQ 441
+Q L+ R+RE + ++
Sbjct: 1808 ALKGGKKQIQKLEARVRELESEVE 1831
Score = 33.5 bits (75), Expect = 0.44
Identities = 37/176 (21%), Positives = 70/176 (39%), Gaps = 24/176 (13%)
Query: 312 NSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTD--------------VKNKLQ 357
N +QL+ +AE +++ Q T + A+I EVT+ K KL+
Sbjct: 889 NDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE 948
Query: 358 TQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVN 417
+ ++ ++I E T+ +E+ A E +K + D KL
Sbjct: 949 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL----------DETIAKLTK 998
Query: 418 EVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRK 473
E + + Q L+ +D + L K +LE ++ +L +K+ CM + +
Sbjct: 999 EKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLER 1054
Score = 29.6 bits (65), Expect = 6.4
Identities = 43/208 (20%), Positives = 88/208 (42%), Gaps = 32/208 (15%)
Query: 198 EKRIGIDLVHDNVEKNLIREVDLLKCCQE---QMRKLAQRIDIQMRDNRD-AQHVLERDL 253
EK + + ++++ + E D L +E Q+ K +++ ++++ + A+ E +
Sbjct: 879 EKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINA 938
Query: 254 EDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANS 313
E + + ++++C L+ D + T AK + KH+ + +
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLEL---------------TLAKVEKE--KHATENKVKN 981
Query: 314 IQLREEAEHLFETLS---------DQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTL 364
L EE L ET++ + +Q D +++ +T K KL+ Q+
Sbjct: 982 --LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLE 1039
Query: 365 QEIFQAENTIMLLERSIMAKEGPLKVAQ 392
+ Q + M LER+ EG LK+AQ
Sbjct: 1040 GSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 38.9 bits (89), Expect = 0.011
Identities = 65/334 (19%), Positives = 134/334 (40%), Gaps = 44/334 (13%)
Query: 96 QSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSEL 155
Q+ + Q+R E + TDD ++ + ++Q+ + + T L Q L L
Sbjct: 195 QAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQEL-------DTL 247
Query: 156 SYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLY----HREKRIGIDLVHDNVE 211
+LD +QN++ E A ++V + E LY HR++ I D ++
Sbjct: 248 QQQLD-----SQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAED---KSIG 299
Query: 212 KNLIREVDLLKCCQEQMRKLA----QRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
+ LLK ++ +++A Q D + + N+ + + + D++ + +++K
Sbjct: 300 SPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYK 359
Query: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAE---HLF 324
L+ + + F ET+ + N +K + AN + L E +
Sbjct: 360 ELKKREEHMDTF------------IETFEETKNQELKRKAQIEANIVALLEHCSRNINRI 407
Query: 325 ETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAK 384
E +S ++ N + +EV ++ Q L +Q + + LLE + +
Sbjct: 408 EQISSITNQELKMMQDDLNFKSTEVQKSQSTAQ-NLTSDIQRLQLDLQKMELLESKMTEE 466
Query: 385 EGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNE 418
+ LK + + ++E+ D+P LK E
Sbjct: 467 QHSLK-----SKIKQMTTDLEIYNDLPALKSSGE 495
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 38.9 bits (89), Expect = 0.011
Identities = 65/334 (19%), Positives = 134/334 (40%), Gaps = 44/334 (13%)
Query: 96 QSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSEL 155
Q+ + Q+R E + TDD ++ + ++Q+ + + T L Q L L
Sbjct: 195 QAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQEL-------DTL 247
Query: 156 SYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLY----HREKRIGIDLVHDNVE 211
+LD +QN++ E A ++V + E LY HR++ I D ++
Sbjct: 248 QQQLD-----SQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAED---KSIG 299
Query: 212 KNLIREVDLLKCCQEQMRKLA----QRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
+ LLK ++ +++A Q D + + N+ + + + D++ + +++K
Sbjct: 300 SPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYK 359
Query: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAE---HLF 324
L+ + + F ET+ + N +K + AN + L E +
Sbjct: 360 ELKKREEHMDTF------------IETFEETKNQELKRKAQIEANIVALLEHCSRNINRI 407
Query: 325 ETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAK 384
E +S ++ N + +EV ++ Q L +Q + + LLE + +
Sbjct: 408 EQISSITNQELKMMQDDLNFKSTEVQKSQSTAQ-NLTSDIQRLQLDLQKMELLESKMTEE 466
Query: 385 EGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNE 418
+ LK + + ++E+ D+P LK E
Sbjct: 467 QHSLK-----SKIKQMTTDLEIYNDLPALKSSGE 495
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 38.9 bits (89), Expect = 0.011
Identities = 65/334 (19%), Positives = 134/334 (40%), Gaps = 44/334 (13%)
Query: 96 QSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSEL 155
Q+ + Q+R E + TDD ++ + ++Q+ + + T L Q L L
Sbjct: 195 QAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQEL-------DTL 247
Query: 156 SYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLY----HREKRIGIDLVHDNVE 211
+LD +QN++ E A ++V + E LY HR++ I D ++
Sbjct: 248 QQQLD-----SQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAED---KSIG 299
Query: 212 KNLIREVDLLKCCQEQMRKLA----QRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCF 267
+ LLK ++ +++A Q D + + N+ + + + D++ + +++K
Sbjct: 300 SPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYK 359
Query: 268 NLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAE---HLF 324
L+ + + F ET+ + N +K + AN + L E +
Sbjct: 360 ELKKREEHMDTF------------IETFEETKNQELKRKAQIEANIVALLEHCSRNINRI 407
Query: 325 ETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAK 384
E +S ++ N + +EV ++ Q L +Q + + LLE + +
Sbjct: 408 EQISSITNQELKMMQDDLNFKSTEVQKSQSTAQ-NLTSDIQRLQLDLQKMELLESKMTEE 466
Query: 385 EGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNE 418
+ LK + + ++E+ D+P LK E
Sbjct: 467 QHSLK-----SKIKQMTTDLEIYNDLPALKSSGE 495
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 38.5 bits (88), Expect = 0.014
Identities = 62/346 (17%), Positives = 134/346 (38%), Gaps = 45/346 (13%)
Query: 96 QSNQLQVRGAEASRLWASR-----LTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGF 150
+ +Q+ RGA + +R L D + ++ +L ++ E RN+
Sbjct: 654 EGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNI--------- 704
Query: 151 WKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNV 210
++ E+D+L+ + Q +ET +R+ + + + + +++ E EK +
Sbjct: 705 --ERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTF--------M 754
Query: 211 EKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLR 270
K R + L+ M + + ++ + +Q LED+ ++++ L+
Sbjct: 755 PKQ--RSLQSLEASLHAMESTRESLKAELGTDLLSQ----LSLEDQKRVDALNDEIRQLQ 808
Query: 271 NTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQ 330
+ + K++G I+ ET+ ++N+R Q+ +E L ET
Sbjct: 809 QENR--QLLNERIKLEGIITRVETYL---------NENLRKRLDQVEQELNELRETEGGT 857
Query: 331 MWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKV 390
+ T A N R+ + L + KT I + + ++ + +
Sbjct: 858 VLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINH 917
Query: 391 AQTRLECRTRRPNMELCRDIPQLKLVNEVFTID----DTLQTLKLR 432
LE T R M L + +K + E+ ++ + QTL L+
Sbjct: 918 DTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLK 963
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 38.5 bits (88), Expect = 0.014
Identities = 82/384 (21%), Positives = 158/384 (41%), Gaps = 46/384 (11%)
Query: 93 DWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQ--EGTCRNLGQRLSDIGF 150
+W Q + EAS+ A L + ++ ++ Q++ + +NL Q +SD+
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL-- 1518
Query: 151 WKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRI-----GIDL 205
+E E + + E LE +K+++E E+ L+ A L H E +I ++
Sbjct: 1519 --TEQIAEGGKRIHE---LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 206 VHDNVEKNLI---REVDLLKCCQEQ-MRKLAQRIDIQMRDNRDA---QHVLERDLED--- 255
V V++ + E+D LK + + + +D ++R DA + +E DL +
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 256 --KSSAQCIDEKCFNLRNTSDCI--------SFFHGMEKIDGTISVPETWAKFSNDNIKH 305
+ + E N RNT + E + +++ E A I+
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 306 SQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQ 365
+ + + R+ AE S+++ T N + TD+ +++Q ++ LQ
Sbjct: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI-SQMQGEMEDILQ 1752
Query: 366 EIFQAENTI--MLLERSIMAKEGPLKVAQ-TRLECRTRRPNMELCRDIPQLKLVNEVFTI 422
E AE + + ++MA+E LK Q T + NME QL+L +E +
Sbjct: 1753 EARNAEEKAKKAITDAAMMAEE--LKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQL 1809
Query: 423 -----DDTLQTLKLRLRETQDTLQ 441
+Q L+ R+RE + ++
Sbjct: 1810 ALKGGKKQIQKLEARVRELEGEVE 1833
Score = 29.3 bits (64), Expect = 8.4
Identities = 36/176 (20%), Positives = 69/176 (39%), Gaps = 24/176 (13%)
Query: 312 NSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTD--------------VKNKLQ 357
N +QL+ +AE +++ Q T + A+I EVT+ K KL+
Sbjct: 891 NDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE 950
Query: 358 TQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVN 417
+ ++ ++I E T+ +E+ A E +K + D KL
Sbjct: 951 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM----------AGLDETIAKLTK 1000
Query: 418 EVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRK 473
E + + Q L+ +D + L K +LE ++ +L +K+ M + +
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 38.5 bits (88), Expect = 0.014
Identities = 82/384 (21%), Positives = 158/384 (41%), Gaps = 46/384 (11%)
Query: 93 DWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQ--EGTCRNLGQRLSDIGF 150
+W Q + EAS+ A L + ++ ++ Q++ + +NL Q +SD+
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL-- 1518
Query: 151 WKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRI-----GIDL 205
+E E + + E LE +K+++E E+ L+ A L H E +I ++
Sbjct: 1519 --TEQIAEGGKRIHE---LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 206 VHDNVEKNLI---REVDLLKCCQEQ-MRKLAQRIDIQMRDNRDA---QHVLERDLED--- 255
V V++ + E+D LK + + + +D ++R DA + +E DL +
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 256 --KSSAQCIDEKCFNLRNTSDCI--------SFFHGMEKIDGTISVPETWAKFSNDNIKH 305
+ + E N RNT + E + +++ E A I+
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 306 SQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQ 365
+ + + R+ AE S+++ T N + TD+ +++Q ++ LQ
Sbjct: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI-SQMQGEMEDILQ 1752
Query: 366 EIFQAENTI--MLLERSIMAKEGPLKVAQ-TRLECRTRRPNMELCRDIPQLKLVNEVFTI 422
E AE + + ++MA+E LK Q T + NME QL+L +E +
Sbjct: 1753 EARNAEEKAKKAITDAAMMAEE--LKKEQDTSAHLERMKKNMEQTVKDLQLRL-DEAEQL 1809
Query: 423 -----DDTLQTLKLRLRETQDTLQ 441
+Q L+ R+RE + ++
Sbjct: 1810 ALKGGKKQIQKLEARVRELEGEVE 1833
Score = 29.3 bits (64), Expect = 8.4
Identities = 36/176 (20%), Positives = 69/176 (39%), Gaps = 24/176 (13%)
Query: 312 NSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTD--------------VKNKLQ 357
N +QL+ +AE +++ Q T + A+I EVT+ K KL+
Sbjct: 891 NDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE 950
Query: 358 TQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVN 417
+ ++ ++I E T+ +E+ A E +K + D KL
Sbjct: 951 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM----------AGLDETIAKLTK 1000
Query: 418 EVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRK 473
E + + Q L+ +D + L K +LE ++ +L +K+ M + +
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 38.1 bits (87), Expect = 0.018
Identities = 51/236 (21%), Positives = 101/236 (42%), Gaps = 20/236 (8%)
Query: 152 KSELSYELD-------RLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGID 204
KSE ELD +++ NLE V R LE ANE L+ A L +
Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQ-RAK 1281
Query: 205 LVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQ-CID 263
L +N E L R+++ + Q+ + QM D L+R LE++ A+ +
Sbjct: 1282 LQTENGE--LARQLEEKEALISQLTRGKLSYTQQMED-------LKRQLEEEGKAKNALA 1332
Query: 264 EKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHL 323
+ R+ D + + E+ + + +K +++ + ++IQ EE E
Sbjct: 1333 HALQSARHDCDLLREQY-EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1391
Query: 324 FETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLER 379
+ L+ ++ + + A NA+ S + K++LQ ++ + ++ ++ L++
Sbjct: 1392 KKKLAQRL-QDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 1446
Score = 30.4 bits (67), Expect = 3.8
Identities = 59/297 (19%), Positives = 116/297 (39%), Gaps = 51/297 (17%)
Query: 93 DWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQ--EGTCRNLGQRLSDIGF 150
+W Q + E+S+ A L+ + +L ++ ++ + +NL + +SD
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD--- 1513
Query: 151 WKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNV 210
L+ +L LE V+++LE E+ L+ A L H E +I + +
Sbjct: 1514 ----LTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKI----LRAQL 1565
Query: 211 EKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLER-----DLEDKSSAQCIDEK 265
E N I+ E RKLA++ + + R+ Q V++ D E +S + + K
Sbjct: 1566 EFNQIK--------AEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVK 1617
Query: 266 CFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFE 325
+K++G ++ E + H+ M A + + + + L +
Sbjct: 1618 -----------------KKMEGDLNEMEI-------QLSHANRMAAEAQKQVKSLQSLLK 1653
Query: 326 TLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIM 382
Q+ N I+ V N LQ +L + + Q E + L E+ ++
Sbjct: 1654 DTQIQL-DDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1709
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 38.1 bits (87), Expect = 0.018
Identities = 79/381 (20%), Positives = 165/381 (43%), Gaps = 34/381 (8%)
Query: 119 SMRLLQDKDQLT--HQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRL 176
++++ + K QLT Q E NL L + K+EL LD L EN L+ +K +
Sbjct: 1660 NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQH 1719
Query: 177 ECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRID 236
+ +E+ QVA+ E+++ ++ + + + E++ K E+ ++ +R+
Sbjct: 1720 DQRVSELE-KTQVAV-----LEEKLELENL-QQISQQQKGEIEWQKQLLERDKREIERMT 1772
Query: 237 IQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFH--------GMEKIDGT 288
+ R + L ++ ED I EK L T ++ +EK++
Sbjct: 1773 AESRALQSCVECLSKEKEDLQEKCDIWEK--KLAQTKRVLAAAEENSKMEQSNLEKLELN 1830
Query: 289 I-SVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARIS 347
+ + + + + D + ++ A QL+E+ E + +L +++ NLA +
Sbjct: 1831 VRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAV-NSLQEELANVQDHLNLA-KQDLL 1888
Query: 348 EVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELC 407
T ++ L ++ + ++I + N ++ K+ L+V Q +E ++L
Sbjct: 1889 HTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE----ENKLKLV 1944
Query: 408 -RDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQL-LVMTKCRLEHELA------IKAN 459
+++ +L E + + L+T K+ L+E Q L+ L K +L+ L+ +
Sbjct: 1945 QQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVR 2004
Query: 460 TLCIDKEKCMGMRKTFPCTPR 480
TL ++ C + KT T R
Sbjct: 2005 TLQEEERWCESLEKTLSQTKR 2025
>gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens]
Length = 962
Score = 37.7 bits (86), Expect = 0.024
Identities = 64/273 (23%), Positives = 114/273 (41%), Gaps = 46/273 (16%)
Query: 207 HDNVE---KNLIREVDL-----------LKCCQEQMRKLAQRIDIQMRDNRDAQHVLERD 252
HDN+ KN+IRE DL LKC EQ++ + Q++ ++D ++L+
Sbjct: 648 HDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQ 707
Query: 253 LEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRAN 312
L + Q S+ G + ++G PE + + + +N
Sbjct: 708 LGKDNQHQG---------------SYSEGAQ-MNGI--QPEEIGRLREEIEELKRNQELL 749
Query: 313 SIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISE-VTDVKNKLQT---QLAKTLQEI- 367
QL E+ + S Q ++ +AR SE V ++K +L T QL EI
Sbjct: 750 QSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEIT 809
Query: 368 -FQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNME-----LCRDIPQLKLVNEVFT 421
Q E +L + AK ++ +T T+ ++E L ++ +LK NE+
Sbjct: 810 KLQTEKQELLQKTEAFAKSVEVQ-GETETIIATKTTDVEGRLSALLQETKELK--NEIKA 866
Query: 422 IDDTLQTLKLRLRETQDTLQLLVMTKCRLEHEL 454
+ + +K +L + T+ +L K +LE E+
Sbjct: 867 LSEERTAIKEQLDSSNSTIAILQTEKDKLELEI 899
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 37.7 bits (86), Expect = 0.024
Identities = 83/405 (20%), Positives = 163/405 (40%), Gaps = 74/405 (18%)
Query: 96 QSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQ--EGTCRNLGQRLSDIGFWKS 153
+ NQL+ + E SR ++ LL ++L Q+ EG + L ++S I +S
Sbjct: 280 EKNQLE-QELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQS 338
Query: 154 ELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKN 213
E + +E K+ LE +++ L +
Sbjct: 339 NYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSA---------------------- 376
Query: 214 LIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLE--DKSSAQCIDEKCFNLRN 271
+ E++ +K C E+ K + Q+ + L R+LE +K Q +D + ++N
Sbjct: 377 MASELEEVKRCMERKDKEKAHLASQVEN-------LTRELENGEKQQLQMLD-RLKEIQN 428
Query: 272 TSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQ---LREEAEHLFETL- 327
D E+ + + E + + D K ++ + Q L+EEAE E L
Sbjct: 429 HFDTCE----AERKHADLQISEL-TRHAEDATKQAERYLSELQQSEALKEEAEKRREDLK 483
Query: 328 -----SDQMWR-----------QFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEI--FQ 369
S + W+ + ++T + +++ K++L+TQL LQ+I +
Sbjct: 484 LKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLR 543
Query: 370 AENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTL 429
E +L +R++ +E K + R + ++ + ++EL EV DT+ L
Sbjct: 544 KELNDVLTKRALQEEELHSKEEKLR-DIKSHQADLEL-----------EVKNSLDTIHRL 591
Query: 430 KLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKT 474
+ L++ + + K LE E+A + DK K + M+++
Sbjct: 592 ESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQES 636
Score = 31.2 bits (69), Expect = 2.2
Identities = 68/312 (21%), Positives = 125/312 (40%), Gaps = 46/312 (14%)
Query: 85 LFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEG--TCRNLG 142
L ++ S W ++ R E LT + ++L++KD+L Q+ NL
Sbjct: 484 LKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLR 543
Query: 143 QRLSDI----GFWKSEL-----------SYELDRLLTENQNLETVKRRLECAANEVNCPL 187
+ L+D+ + EL S++ D L +L+T+ R +
Sbjct: 544 KELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQS 603
Query: 188 QVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKL-AQRIDI--QMRDNRD 244
Q+ +E H E+ I ++K+ ++ L QE ++ L A R D+ ++ +
Sbjct: 604 QMKVE-KAHLEEEIA------ELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEER 656
Query: 245 AQHVLERDLED-KSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNI 303
A+ + +DL D + A+ DE+ + H E D T S+
Sbjct: 657 AKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSV-------KT 709
Query: 304 KHSQNMR---ANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQL 360
KH QN++ + + + EAE+ TL + + N+A R KL++Q
Sbjct: 710 KHEQNIQELMKHFKKEKSEAENHIRTLKAE---SLEEKNMAKIHR-----GQLEKLKSQC 761
Query: 361 AKTLQEIFQAEN 372
+ +E+ Q EN
Sbjct: 762 DRLTEELTQNEN 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,320,060
Number of Sequences: 37866
Number of extensions: 723914
Number of successful extensions: 2520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 2316
Number of HSP's gapped (non-prelim): 329
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.