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Search of human proteins with 21361745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
(672 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 1344 0.0
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 726 0.0
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 726 0.0
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 723 0.0
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 723 0.0
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 723 0.0
gi|34101286 zinc finger RNA binding protein [Homo sapiens] 358 7e-99
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s... 326 5e-89
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 166 5e-41
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 166 5e-41
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 166 5e-41
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 166 5e-41
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 121 2e-27
gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens] 99 2e-20
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 69 1e-11
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 66 1e-10
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 66 1e-10
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 66 1e-10
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 60 5e-09
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 60 5e-09
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 60 5e-09
gi|7657625 staufen homolog 2 [Homo sapiens] 58 3e-08
gi|82659089 staufen isoform a [Homo sapiens] 56 1e-07
gi|82659087 staufen isoform b [Homo sapiens] 56 1e-07
gi|82659085 staufen isoform a [Homo sapiens] 56 1e-07
gi|82659083 staufen isoform a [Homo sapiens] 56 1e-07
gi|82659091 staufen isoform c [Homo sapiens] 55 2e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 47 4e-05
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 47 4e-05
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 47 4e-05
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 1344 bits (3478), Expect = 0.0
Identities = 672/672 (100%), Positives = 672/672 (100%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG
Sbjct: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
Query: 61 ETEVKKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNT 120
ETEVKKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNT
Sbjct: 61 ETEVKKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNT 120
Query: 121 VKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN 180
VKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN
Sbjct: 121 VKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGEN 180
Query: 181 VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKG 240
VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKG
Sbjct: 181 VSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKG 240
Query: 241 WPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTI 300
WPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTI
Sbjct: 241 WPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTI 300
Query: 301 QQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE 360
QQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE
Sbjct: 301 QQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFE 360
Query: 361 DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTM 420
DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTM
Sbjct: 361 DGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTM 420
Query: 421 SVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVS 480
SVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVS
Sbjct: 421 SVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVS 480
Query: 481 SNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR 540
SNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR
Sbjct: 481 SNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKR 540
Query: 541 FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAV 600
FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAV
Sbjct: 541 FVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKIIPQAKGVVNTAV 600
Query: 601 SAAVQAVRGRGRGTLTRGAFVGATAAPGYIAPGYGTPYGYSTAAPAYGLPKRMVLLPVMK 660
SAAVQAVRGRGRGTLTRGAFVGATAAPGYIAPGYGTPYGYSTAAPAYGLPKRMVLLPVMK
Sbjct: 601 SAAVQAVRGRGRGTLTRGAFVGATAAPGYIAPGYGTPYGYSTAAPAYGLPKRMVLLPVMK 660
Query: 661 FPTYPVPHYSFF 672
FPTYPVPHYSFF
Sbjct: 661 FPTYPVPHYSFF 672
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 726 bits (1873), Expect = 0.0
Identities = 401/690 (58%), Positives = 491/690 (71%), Gaps = 59/690 (8%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ +
Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60
Query: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112
E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K
Sbjct: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119
Query: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172
PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E
Sbjct: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179
Query: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231
+EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R
Sbjct: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239
Query: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291
VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++
Sbjct: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299
Query: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344
TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ +
Sbjct: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359
Query: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404
+ +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY
Sbjct: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418
Query: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464
KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG +
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478
Query: 465 SSDEKSDNESKN---------ETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPV 515
D + E+K E VS+ S+ ++T E V+ QGPILT GKNPV
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE-----NVKQQGPILTKHGKNPV 533
Query: 516 MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF 575
MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF
Sbjct: 534 MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLF 593
Query: 576 -SGPNA--ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTR 617
P A AN KK+ +P G A +RGRGRG R
Sbjct: 594 PDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIR 653
Query: 618 G-----AFVGATAAPGYI--APGYGTPYGY 640
G F GA GY+ GYG+ YGY
Sbjct: 654 GRGRGRGFGGANHG-GYMNAGAGYGS-YGY 681
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 726 bits (1873), Expect = 0.0
Identities = 401/690 (58%), Positives = 491/690 (71%), Gaps = 59/690 (8%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ +
Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60
Query: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112
E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K
Sbjct: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119
Query: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172
PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E
Sbjct: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179
Query: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231
+EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R
Sbjct: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239
Query: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291
VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++
Sbjct: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299
Query: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344
TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ +
Sbjct: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359
Query: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404
+ +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY
Sbjct: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418
Query: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464
KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG +
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478
Query: 465 SSDEKSDNESKN---------ETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPV 515
D + E+K E VS+ S+ ++T E V+ QGPILT GKNPV
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE-----NVKQQGPILTKHGKNPV 533
Query: 516 MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF 575
MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF
Sbjct: 534 MELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLF 593
Query: 576 -SGPNA--ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTR 617
P A AN KK+ +P G A +RGRGRG R
Sbjct: 594 PDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIR 653
Query: 618 G-----AFVGATAAPGYI--APGYGTPYGY 640
G F GA GY+ GYG+ YGY
Sbjct: 654 GRGRGRGFGGANHG-GYMNAGAGYGS-YGY 681
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 723 bits (1866), Expect = 0.0
Identities = 398/684 (58%), Positives = 490/684 (71%), Gaps = 51/684 (7%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ +
Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60
Query: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112
E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K
Sbjct: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119
Query: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172
PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E
Sbjct: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179
Query: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231
+EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R
Sbjct: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239
Query: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291
VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++
Sbjct: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299
Query: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344
TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ +
Sbjct: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359
Query: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404
+ +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY
Sbjct: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418
Query: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464
KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG +
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478
Query: 465 SSDEKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEK 521
D + E+K V+ + +T ++ + +T E QGPILT GKNPVMELNEK
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE---QGPILTKHGKNPVMELNEK 535
Query: 522 RRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF-SGPNA 580
RRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF P A
Sbjct: 536 RRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Query: 581 --ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTRG----- 618
AN KK+ +P G A +RGRGRG RG
Sbjct: 596 LDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGR 655
Query: 619 AFVGATAAPGYI--APGYGTPYGY 640
F GA GY+ GYG+ YGY
Sbjct: 656 GFGGANHG-GYMNAGAGYGS-YGY 677
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 723 bits (1866), Expect = 0.0
Identities = 398/684 (58%), Positives = 490/684 (71%), Gaps = 51/684 (7%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ +
Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60
Query: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112
E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K
Sbjct: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119
Query: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172
PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E
Sbjct: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179
Query: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231
+EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R
Sbjct: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239
Query: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291
VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++
Sbjct: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299
Query: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344
TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ +
Sbjct: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359
Query: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404
+ +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY
Sbjct: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418
Query: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464
KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG +
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478
Query: 465 SSDEKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEK 521
D + E+K V+ + +T ++ + +T E QGPILT GKNPVMELNEK
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE---QGPILTKHGKNPVMELNEK 535
Query: 522 RRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF-SGPNA 580
RRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF P A
Sbjct: 536 RRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Query: 581 --ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTRG----- 618
AN KK+ +P G A +RGRGRG RG
Sbjct: 596 LDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGR 655
Query: 619 AFVGATAAPGYI--APGYGTPYGY 640
F GA GY+ GYG+ YGY
Sbjct: 656 GFGGANHG-GYMNAGAGYGS-YGY 677
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 723 bits (1866), Expect = 0.0
Identities = 398/684 (58%), Positives = 490/684 (71%), Gaps = 51/684 (7%)
Query: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60
MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ +
Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60
Query: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112
E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K
Sbjct: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119
Query: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172
PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E
Sbjct: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179
Query: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231
+EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R
Sbjct: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239
Query: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291
VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++
Sbjct: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299
Query: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344
TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ +
Sbjct: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359
Query: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404
+ +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY
Sbjct: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418
Query: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464
KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG +
Sbjct: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478
Query: 465 SSDEKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEK 521
D + E+K V+ + +T ++ + +T E QGPILT GKNPVMELNEK
Sbjct: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE---QGPILTKHGKNPVMELNEK 535
Query: 522 RRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF-SGPNA 580
RRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF P A
Sbjct: 536 RRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Query: 581 --ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTRG----- 618
AN KK+ +P G A +RGRGRG RG
Sbjct: 596 LDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGR 655
Query: 619 AFVGATAAPGYI--APGYGTPYGY 640
F GA GY+ GYG+ YGY
Sbjct: 656 GFGGANHG-GYMNAGAGYGS-YGY 677
>gi|34101286 zinc finger RNA binding protein [Homo sapiens]
Length = 1074
Score = 358 bits (920), Expect = 7e-99
Identities = 188/365 (51%), Positives = 256/365 (70%), Gaps = 13/365 (3%)
Query: 5 RSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEV 64
R ++DDR+VM KH+TIYP+ EEL+AVQ +VS E ALK VSD L E K EG+
Sbjct: 718 RPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEKNKNKEGDD-- 775
Query: 65 KKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDN 124
K E G++ R L GV+R+G++AKGLL++ D ++ LVL+C +KP++TLL+ + +N
Sbjct: 776 -KKEGGKD-------RALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRIAEN 827
Query: 125 LPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE-LEKKDGENVSM 183
LP Q+ ++ EKY ++ V+EA+II+ + EP + + + LTSP+IR+E + + D + +
Sbjct: 828 LPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMV 887
Query: 184 KDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPL 243
KDPPD+LDRQKCL+ALA+LRHAKWFQARANGL+SCVI++RILRDLC RVPTW+ W +
Sbjct: 888 KDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAM 947
Query: 244 ELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTIQQK 303
EL+ EK+I + + P G+ALRRV EC++SGI+L G PGL DPCE+DP D L+ MT QQ+
Sbjct: 948 ELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQR 1007
Query: 304 EDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGL 363
EDIT SAQ ALRL AF QI+KVL MDPLP Q+++ K S + +G
Sbjct: 1008 EDITSSAQFALRLLAFRQIHKVLGMDPLPQMS--QRFNIHNNRKRRRDSDGVDGFEAEGK 1065
Query: 364 GDDKD 368
D KD
Sbjct: 1066 KDKKD 1070
>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
sapiens]
Length = 939
Score = 326 bits (835), Expect = 5e-89
Identities = 175/364 (48%), Positives = 240/364 (65%), Gaps = 14/364 (3%)
Query: 5 RSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEGETEV 64
R ++DDRHVM KH+TIYP+ +EL AVQ VS E ALK VSD L E ++G + E
Sbjct: 584 RPASSDDRHVMCKHATIYPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREE----- 638
Query: 65 KKDEAGENYSKDQGGRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDN 124
E + S R L GVMR+G++AKGLL++ D ++ L L+C +KPT +LL +
Sbjct: 639 ---EGDKRSSVAPQTRVLKGVMRVGILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQ 695
Query: 125 LPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGENVSMK 184
LP Q+Q +TE++Y+V EA+I+I + +EP + + + +TSPL+R++ G
Sbjct: 696 LPRQLQMVTEDEYEVSSDP-EANIVISSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQA 754
Query: 185 DPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLE 244
D D+L +KCL +LA+LRHA+WFQARA+GL+ CVIV+R+LRDLC RVPTW L W +E
Sbjct: 755 DAGDVLSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGALPAWAME 814
Query: 245 LICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTIQQKE 304
L+ EK++ + PLG G+A+RRV+EC+A+G LL GPGL DPCERD TDAL MT+Q++E
Sbjct: 815 LLVEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGPGLQDPCERDQTDALEPMTLQERE 874
Query: 305 DITHSAQHALRLSAFGQIYKVLEMDPLPS----SKPFQKYSWSVTD-KEGAGSSALKRPF 359
D+T SAQHALR+ AF Q +KVL MD LP F+K + +EGAG R
Sbjct: 875 DVTASAQHALRMLAFRQTHKVLGMDLLPPRHRLGARFRKRQRGPGEGEEGAGEKKRGRRG 934
Query: 360 EDGL 363
+GL
Sbjct: 935 GEGL 938
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 166 bits (421), Expect = 5e-41
Identities = 111/260 (42%), Positives = 141/260 (54%), Gaps = 38/260 (14%)
Query: 349 GAGSSALKRPFEDGL-GDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLL 407
G G KRP E+G G K KK ++ +L NALM+LN+I+PGLQY LL
Sbjct: 45 GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPK------NALMQLNEIKPGLQYTLL 98
Query: 408 SQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQ-------------AMGYP 454
SQ+GPVHAP+F MSV+V+G +E SGP+KK AKLH A K L+ AMG
Sbjct: 99 SQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRT 158
Query: 455 TGFDADIECMSSD---------EKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRT 502
+ D +D E D V SN S +++G+ + S
Sbjct: 159 LSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA 218
Query: 503 QGPILT------ASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAG 556
Q P+ SGKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F G+G
Sbjct: 219 QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSG 278
Query: 557 PNKKVAKASAALAALEKLFS 576
NKK+AKA AA +AL +F+
Sbjct: 279 RNKKLAKARAAQSALAAIFN 298
Score = 75.9 bits (185), Expect = 1e-13
Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 501 RTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKK 560
+T GP+L KN +M+LNE + GL+Y L+S+TG H FVM VEV+GQ F G+GP KK
Sbjct: 72 KTPGPVLP---KNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKK 128
Query: 561 VAKASAALAALEKLFSGPNAA 581
AK AA AL PNA+
Sbjct: 129 KAKLHAAEKALRSFVQFPNAS 149
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 166 bits (421), Expect = 5e-41
Identities = 111/260 (42%), Positives = 141/260 (54%), Gaps = 38/260 (14%)
Query: 349 GAGSSALKRPFEDGL-GDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLL 407
G G KRP E+G G K KK ++ +L NALM+LN+I+PGLQY LL
Sbjct: 45 GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPK------NALMQLNEIKPGLQYTLL 98
Query: 408 SQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQ-------------AMGYP 454
SQ+GPVHAP+F MSV+V+G +E SGP+KK AKLH A K L+ AMG
Sbjct: 99 SQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRT 158
Query: 455 TGFDADIECMSSD---------EKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRT 502
+ D +D E D V SN S +++G+ + S
Sbjct: 159 LSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA 218
Query: 503 QGPILT------ASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAG 556
Q P+ SGKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F G+G
Sbjct: 219 QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSG 278
Query: 557 PNKKVAKASAALAALEKLFS 576
NKK+AKA AA +AL +F+
Sbjct: 279 RNKKLAKARAAQSALAAIFN 298
Score = 75.9 bits (185), Expect = 1e-13
Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 501 RTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKK 560
+T GP+L KN +M+LNE + GL+Y L+S+TG H FVM VEV+GQ F G+GP KK
Sbjct: 72 KTPGPVLP---KNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKK 128
Query: 561 VAKASAALAALEKLFSGPNAA 581
AK AA AL PNA+
Sbjct: 129 KAKLHAAEKALRSFVQFPNAS 149
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 166 bits (421), Expect = 5e-41
Identities = 111/260 (42%), Positives = 141/260 (54%), Gaps = 38/260 (14%)
Query: 349 GAGSSALKRPFEDGL-GDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLL 407
G G KRP E+G G K KK ++ +L NALM+LN+I+PGLQY LL
Sbjct: 45 GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPK------NALMQLNEIKPGLQYTLL 98
Query: 408 SQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQ-------------AMGYP 454
SQ+GPVHAP+F MSV+V+G +E SGP+KK AKLH A K L+ AMG
Sbjct: 99 SQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRT 158
Query: 455 TGFDADIECMSSD---------EKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRT 502
+ D +D E D V SN S +++G+ + S
Sbjct: 159 LSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA 218
Query: 503 QGPILT------ASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAG 556
Q P+ SGKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F G+G
Sbjct: 219 QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSG 278
Query: 557 PNKKVAKASAALAALEKLFS 576
NKK+AKA AA +AL +F+
Sbjct: 279 RNKKLAKARAAQSALAAIFN 298
Score = 75.9 bits (185), Expect = 1e-13
Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 501 RTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKK 560
+T GP+L KN +M+LNE + GL+Y L+S+TG H FVM VEV+GQ F G+GP KK
Sbjct: 72 KTPGPVLP---KNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKK 128
Query: 561 VAKASAALAALEKLFSGPNAA 581
AK AA AL PNA+
Sbjct: 129 KAKLHAAEKALRSFVQFPNAS 149
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 166 bits (421), Expect = 5e-41
Identities = 111/260 (42%), Positives = 141/260 (54%), Gaps = 38/260 (14%)
Query: 349 GAGSSALKRPFEDGL-GDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLL 407
G G KRP E+G G K KK ++ +L NALM+LN+I+PGLQY LL
Sbjct: 45 GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPK------NALMQLNEIKPGLQYTLL 98
Query: 408 SQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQ-------------AMGYP 454
SQ+GPVHAP+F MSV+V+G +E SGP+KK AKLH A K L+ AMG
Sbjct: 99 SQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRT 158
Query: 455 TGFDADIECMSSD---------EKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRT 502
+ D +D E D V SN S +++G+ + S
Sbjct: 159 LSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA 218
Query: 503 QGPILT------ASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAG 556
Q P+ SGKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F G+G
Sbjct: 219 QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSG 278
Query: 557 PNKKVAKASAALAALEKLFS 576
NKK+AKA AA +AL +F+
Sbjct: 279 RNKKLAKARAAQSALAAIFN 298
Score = 75.9 bits (185), Expect = 1e-13
Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 501 RTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKK 560
+T GP+L KN +M+LNE + GL+Y L+S+TG H FVM VEV+GQ F G+GP KK
Sbjct: 72 KTPGPVLP---KNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKK 128
Query: 561 VAKASAALAALEKLFSGPNAA 581
AK AA AL PNA+
Sbjct: 129 KAKLHAAEKALRSFVQFPNAS 149
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 121 bits (303), Expect = 2e-27
Identities = 83/254 (32%), Positives = 136/254 (53%), Gaps = 32/254 (12%)
Query: 349 GAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLS 408
GA + KRP E+G G + + + L S ++ NAL++L+++RPGLQY+ +S
Sbjct: 92 GAPGAKRKRPLEEGNGGHLCKLQLVWKKL-----SWSVAPKNALVQLHELRPGLQYRTVS 146
Query: 409 QSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA-MGYPTGFDADIEC---- 463
Q+GPVHAPVF ++V+V+G T+E +GP+KK AK+ A L++ + +P A +
Sbjct: 147 QTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
Query: 464 -MSSDEKSDNESKNETVSSN----------SSNNTGNSTTETSS---------TLEVRTQ 503
+D SD +T+ + G++ +++ L++
Sbjct: 207 GPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGP 266
Query: 504 GPILTAS--GKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKV 561
P A+ +NPV+ LN R GL+Y ++E + FVM V VDG+ F G+G +KK+
Sbjct: 267 TPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKL 326
Query: 562 AKASAALAALEKLF 575
A+ AA AAL++LF
Sbjct: 327 ARGQAAQAALQELF 340
Score = 61.6 bits (148), Expect = 2e-09
Identities = 32/69 (46%), Positives = 41/69 (59%)
Query: 512 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAAL 571
KN +++L+E R GL+Y +S+TG H F + VEV+G F G GP KK AK AA AL
Sbjct: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
Query: 572 EKLFSGPNA 580
PNA
Sbjct: 187 RSFVQFPNA 195
>gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens]
Length = 390
Score = 98.6 bits (244), Expect = 2e-20
Identities = 76/291 (26%), Positives = 142/291 (48%), Gaps = 24/291 (8%)
Query: 85 VMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVN 144
V ++G KG + +LV++ K PT + + N ++ + + + N
Sbjct: 102 VRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAAL-GNKVVESLRAQDPSEVLTMLTN 160
Query: 145 EASIIIRNTKEPTLTLKVILTSPLIRDELEKKDGENVSMKDPPDLLDRQKCLNALASLRH 204
E I ++ T+K+++T+ N+ DP LD + +ALA++RH
Sbjct: 161 ETGFEISSSDA---TVKILITTV----------PPNLRKLDPELHLDIKVLQSALAAIRH 207
Query: 205 AKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKSI--GTCNRPLGAGE 262
A+WF+ A+ + +++R+L+DL R P + PL W L+L+ ++ +PL
Sbjct: 208 ARWFEENASQ-STVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNV 266
Query: 263 ALRRVMECLASGILLPGGPGLHDPCERDPTDALSYMTIQQKEDITHSAQHALRLSAFGQI 322
A RR ++ LA+G+ LPG G+ DPCE + MT++Q++ + ++AQ +R+ + G
Sbjct: 267 AYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGF 326
Query: 323 YKVLEMDPLPSSKPFQKYSWS---VTDKEGAGSSALKRPFEDGLGDDKDPN 370
K+L + S + +W VT E A ++P E G++++ N
Sbjct: 327 RKILGQEGDASYLASEISTWDGVIVTPSE----KAYEKPPEKKEGEEEEEN 373
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/220 (28%), Positives = 101/220 (45%), Gaps = 30/220 (13%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
Query: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 575 F---SGPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRG 611
+ A++N+ +KI + + V ++ R G
Sbjct: 681 HGEATNSMASDNQVRKIGELVRYLNTNPVGGLLEYARSHG 720
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/186 (26%), Positives = 79/186 (42%), Gaps = 41/186 (22%)
Query: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGY 453
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+
Sbjct: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL-- 680
Query: 454 PTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKN 513
G +T +S +VR G ++ N
Sbjct: 681 ---------------------------------HGEATNSMASDNQVRKIGELVRYLNTN 707
Query: 514 PVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAAL 568
PV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
Query: 569 AALEKL 574
AAL L
Sbjct: 768 AALRVL 773
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 65.9 bits (159), Expect = 1e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 271
Query: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 272 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 325
Query: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 326 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
Query: 575 F---SGPNAANNKKKKIIPQA 592
+ A++N+ + +I ++
Sbjct: 386 HGEATNSMASDNQPEGMISES 406
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 328 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 387
Query: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 388 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 430
Query: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 431 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 490
Query: 568 LAALEKL 574
AAL L
Sbjct: 491 DAALRVL 497
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 65.9 bits (159), Expect = 1e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
Query: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 575 F---SGPNAANNKKKKIIPQA 592
+ A++N+ + +I ++
Sbjct: 681 HGEATNSMASDNQPEGMISES 701
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 682
Query: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 683 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 725
Query: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 726 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 785
Query: 568 LAALEKL 574
AAL L
Sbjct: 786 DAALRVL 792
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 65.9 bits (159), Expect = 1e-10
Identities = 58/201 (28%), Positives = 96/201 (47%), Gaps = 30/201 (14%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
++ ++ QSGP H P F V ++G + A SKK AK A+K +
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 462 ECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTA--SGKNPVMELN 519
+ + K+ + K+E S S+ E+ T E +T P T+ SGK+PV L
Sbjct: 567 TILLEEAKAKDSGKSEESSHYSTEK------ESEKTAESQTPTPSATSFFSGKSPVTTLL 620
Query: 520 EKRRGL----KYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAALAALEKL 574
E L ++ L+S+ G +H+ +F V V Q F + P+KKVAK AA A++ L
Sbjct: 621 ECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Query: 575 F---SGPNAANNKKKKIIPQA 592
+ A++N+ + +I ++
Sbjct: 681 HGEATNSMASDNQPEGMISES 701
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 24/187 (12%)
Query: 395 LNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAM-G 452
++++ +++LLS+ GP H P F V V T+ S PSKK AK A + ++A+ G
Sbjct: 623 MHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHG 682
Query: 453 YPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK 512
T A SDN+ E + S S +N E+ +VR G ++
Sbjct: 683 EATNSMA----------SDNQP--EGMISESLDN-----LESMMPNKVRKIGELVRYLNT 725
Query: 513 NPVMELNEKRR----GLKYELISETGGSHDKRFVMEVEVDGQKFRG-AGPNKKVAKASAA 567
NPV L E R +++L+ ++G H+ +FV + +V G+ F +KK K AA
Sbjct: 726 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 785
Query: 568 LAALEKL 574
AAL L
Sbjct: 786 DAALRVL 792
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 60.5 bits (145), Expect = 5e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 9/217 (4%)
Query: 404 YKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIEC 463
Y LL G H P FT V V T+ GPSKK AK A L+ + + + +E
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 86
Query: 464 MSSDEKSDNESKNE-TVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK-NPVMELNE- 520
SS D+ + V + ++ T + + + + Q P+ + NPV L E
Sbjct: 87 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQEL 146
Query: 521 -KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFS 576
++G + Y + E+G +H K F M V+ G+G +KK+AK +AA L ++ +
Sbjct: 147 VVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHT 206
Query: 577 GPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRG 613
P A + + + + V + + +R RG G
Sbjct: 207 VPLDARDGNE--VEPDDDHFSIGVGSRLDGLRNRGPG 241
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 511 GKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASA 566
GK P+ L E + Y+L+ G +H F V V G GP+KK AK A
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKA 66
Query: 567 ALAALEKLFSG 577
A AL+ L G
Sbjct: 67 AEVALKHLKGG 77
Score = 37.4 bits (85), Expect = 0.045
Identities = 19/46 (41%), Positives = 26/46 (56%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVL 448
+Y + +SGP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 201
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 60.5 bits (145), Expect = 5e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 9/217 (4%)
Query: 404 YKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIEC 463
Y LL G H P FT V V T+ GPSKK AK A L+ + + + +E
Sbjct: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Query: 464 MSSDEKSDNESKNE-TVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK-NPVMELNE- 520
SS D+ + V + ++ T + + + + Q P+ + NPV L E
Sbjct: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQEL 167
Query: 521 -KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFS 576
++G + Y + E+G +H K F M V+ G+G +KK+AK +AA L ++ +
Sbjct: 168 VVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHT 227
Query: 577 GPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRG 613
P A + + + + V + + +R RG G
Sbjct: 228 VPLDARDGNE--VEPDDDHFSIGVGSRLDGLRNRGPG 262
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 511 GKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASA 566
GK P+ L E + Y+L+ G +H F V V G GP+KK AK A
Sbjct: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKA 87
Query: 567 ALAALEKLFSG 577
A AL+ L G
Sbjct: 88 AEVALKHLKGG 98
Score = 37.4 bits (85), Expect = 0.045
Identities = 19/46 (41%), Positives = 26/46 (56%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVL 448
+Y + +SGP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 60.5 bits (145), Expect = 5e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 9/217 (4%)
Query: 404 YKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIEC 463
Y LL G H P FT V V T+ GPSKK AK A L+ + + + +E
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 86
Query: 464 MSSDEKSDNESKNE-TVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK-NPVMELNE- 520
SS D+ + V + ++ T + + + + Q P+ + NPV L E
Sbjct: 87 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQEL 146
Query: 521 -KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFS 576
++G + Y + E+G +H K F M V+ G+G +KK+AK +AA L ++ +
Sbjct: 147 VVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHT 206
Query: 577 GPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRG 613
P A + + + + V + + +R RG G
Sbjct: 207 VPLDARDGNE--VEPDDDHFSIGVGSRLDGLRNRGPG 241
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 511 GKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASA 566
GK P+ L E + Y+L+ G +H F V V G GP+KK AK A
Sbjct: 7 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKA 66
Query: 567 ALAALEKLFSG 577
A AL+ L G
Sbjct: 67 AEVALKHLKGG 77
Score = 37.4 bits (85), Expect = 0.045
Identities = 19/46 (41%), Positives = 26/46 (56%)
Query: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVL 448
+Y + +SGP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 201
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/283 (24%), Positives = 110/283 (38%), Gaps = 66/283 (23%)
Query: 311 QHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPN 370
+ A R +A + + L+ +P+P P S D DDKD N
Sbjct: 132 RQAARHNAAMKALQALQNEPIPERSPQNGESGKDMD------------------DDKDAN 173
Query: 371 KKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYE 430
K S+ + ++ N + ++++ +SGP H F V V + E
Sbjct: 174 K-----------SEISLVFEIALKRNM---PVSFEVIKESGPPHMKSFVTRVSVGEFSAE 219
Query: 431 ASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNS 490
G SKK +K A VLQ + + + EK K +
Sbjct: 220 GEGNSKKLSKKRAATTVLQEL-------KKLPPLPVVEKPKLFFKKRPKT---------- 262
Query: 491 TTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLK-----YELISETGGSHDKRFVMEV 545
+ GP G NP+ L + ++ K Y L+SE G + FVM+V
Sbjct: 263 ---------IVKAGPEY-GQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
Query: 546 EVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKI 588
+V + G GPNKK+AK +AA A L +L G A+ N + ++
Sbjct: 313 KVGNEVATGTGPNKKIAKKNAAEAMLLQL--GYKASTNLQDQL 353
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/179 (25%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 414 HAPV---FTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKS 470
H PV F + + V + G +++ A+ + A+K LQA+
Sbjct: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQAL------------------- 147
Query: 471 DNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYEL 529
+NE + S N G S + + L V E+ KR + +E+
Sbjct: 148 ----QNEPIPERSPQN-GESGKDMDDDKDANKSEISL-------VFEIALKRNMPVSFEV 195
Query: 530 ISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGPNAANNKKKKI 588
I E+G H K FV V V G G +KK++K AA L++L P +K K+
Sbjct: 196 IKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKL 254
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 171
Query: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
+ + E+ K +T V +S G S +++
Sbjct: 172 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 216
Query: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 217 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 275
Query: 578 PNAANNK 584
P A K
Sbjct: 276 PQAQPTK 282
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 79
Query: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 80 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 124
Query: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 125 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 184
Query: 589 IPQAKGVVNTAVS 601
+ K +V S
Sbjct: 185 KKKTKPIVKPQTS 197
Score = 37.7 bits (86), Expect = 0.035
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 444 AVKVLQAMGY 453
A +L+ +G+
Sbjct: 264 AENMLEILGF 273
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 252
Query: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
+ + E+ K +T V +S G S +++
Sbjct: 253 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 297
Query: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 298 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 356
Query: 578 PNAANNK 584
P A K
Sbjct: 357 PQAQPTK 363
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 160
Query: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 161 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 205
Query: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 206 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 265
Query: 589 IPQAKGVVNTAVS 601
+ K +V S
Sbjct: 266 KKKTKPIVKPQTS 278
Score = 37.7 bits (86), Expect = 0.035
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 285 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 344
Query: 444 AVKVLQAMGY 453
A +L+ +G+
Sbjct: 345 AENMLEILGF 354
Score = 31.6 bits (70), Expect = 2.5
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 15/123 (12%)
Query: 468 EKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVME-LNEKRRGLK 526
E + +N + S S +T + + T+E+ + GK P+ + ++ R
Sbjct: 45 ENAGRPIQNSALPSASITSTSAAAESITPTVELNA---LCMKLGKKPMYKPVDPYSRMQS 101
Query: 527 YELISETGGSHDKRFV-----------MEVEVDGQKFRGAGPNKKVAKASAALAALEKLF 575
+ GG++ R+ +E+ V GQ+F G G ++ AK AA AL L
Sbjct: 102 TYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQ 161
Query: 576 SGP 578
+ P
Sbjct: 162 NEP 164
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 171
Query: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
+ + E+ K +T V +S G S +++
Sbjct: 172 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 216
Query: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 217 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 275
Query: 578 PNAANNK 584
P A K
Sbjct: 276 PQAQPTK 282
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 79
Query: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 80 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 124
Query: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 125 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 184
Query: 589 IPQAKGVVNTAVS 601
+ K +V S
Sbjct: 185 KKKTKPIVKPQTS 197
Score = 37.7 bits (86), Expect = 0.035
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 444 AVKVLQAMGY 453
A +L+ +G+
Sbjct: 264 AENMLEILGF 273
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 171
Query: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
+ + E+ K +T V +S G S +++
Sbjct: 172 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 216
Query: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 217 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 275
Query: 578 PNAANNK 584
P A K
Sbjct: 276 PQAQPTK 282
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 79
Query: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 80 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 124
Query: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 125 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 184
Query: 589 IPQAKGVVNTAVS 601
+ K +V S
Sbjct: 185 KKKTKPIVKPQTS 197
Score = 37.7 bits (86), Expect = 0.035
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 444 AVKVLQAMGY 453
A +L+ +G+
Sbjct: 264 AENMLEILGF 273
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/278 (23%), Positives = 108/278 (38%), Gaps = 57/278 (20%)
Query: 311 QHALRLSAFGQIYKVLEMDPLPSSKPFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPN 370
+ A + A + ++L+ +PLP + + +++E S + + FE L
Sbjct: 64 RQAAKHDAAAKALRILQNEPLPERL---EVNGRESEEENLNKSEISQVFEIAL------- 113
Query: 371 KKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYE 430
KRNL +S + ++ +SGP H F V V E
Sbjct: 114 ---KRNLPVNFESFPLK-----------------QVARESGPPHMKNFVTKVSVGEFVGE 153
Query: 431 ASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNET---VSSNSSNNT 487
G SKK +K + A+ VL+ + + + + E+ K +T V +S
Sbjct: 154 GEGKSKKISKKNAAIAVLEEL-------KKLPPLPAVERVKPRIKKKTKPIVKPQTSPEY 206
Query: 488 GNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEV 547
G S +++ +K + +Y L++E G + FVM+V+V
Sbjct: 207 GQGINPISRLAQIQQA----------------KKEKEPEYTLLTERGLPRRREFVMQVKV 250
Query: 548 DGQKFRGAGPNKKVAKASAALAALEKL-FSGPNAANNK 584
G G NKKVAK +AA LE L F P A K
Sbjct: 251 GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTK 288
Score = 45.1 bits (105), Expect = 2e-04
Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 32/193 (16%)
Query: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAM-GYPTGFDADIECMSSDEKS 470
PV ++ + + V G + G +++ AK A K L+ + P ++ S+E++
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
Query: 471 DNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRRGLKYELI 530
N+S E S E+ A +N + +N + LK ++
Sbjct: 100 LNKS------------------EISQVFEI--------ALKRN--LPVNFESFPLK-QVA 130
Query: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 131 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 190
Query: 589 IPQAKGVVNTAVS 601
+ K +V S
Sbjct: 191 KKKTKPIVKPQTS 203
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 517 ELNEKRRG----LKYELISETGGSHDKRFVMEVEVDGQKF-RGAGPNKKVAKASAALAAL 571
ELN R+ LKY+ + +G HD+RF +V +DG++F G G +KK AK +AA A+
Sbjct: 13 ELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAV 72
Query: 572 EKLFSGPNAANNKKKKIIPQAKGVVNTA 599
E L N +KK + P N++
Sbjct: 73 EIL-------NKEKKAVSPLLLTTTNSS 93
Score = 35.0 bits (79), Expect = 0.23
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDAD 460
L+Y+ L SGP H FT V +DG + E G SKK AK + A K+
Sbjct: 25 LKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAK-NAAAKLA------------ 71
Query: 461 IECMSSDEKSDNESKNETVSSNSSNNTGN 489
+E ++ ++K+ + T +S+ + GN
Sbjct: 72 VEILNKEKKAVSPLLLTTTNSSEGLSMGN 100
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 517 ELNEKRRG----LKYELISETGGSHDKRFVMEVEVDGQKF-RGAGPNKKVAKASAALAAL 571
ELN R+ LKY+ + +G HD+RF +V +DG++F G G +KK AK +AA A+
Sbjct: 13 ELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAV 72
Query: 572 EKLFSGPNAANNKKKKIIPQAKGVVNTA 599
E L N +KK + P N++
Sbjct: 73 EIL-------NKEKKAVSPLLLTTTNSS 93
Score = 35.0 bits (79), Expect = 0.23
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDAD 460
L+Y+ L SGP H FT V +DG + E G SKK AK + A K+
Sbjct: 25 LKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAK-NAAAKLA------------ 71
Query: 461 IECMSSDEKSDNESKNETVSSNSSNNTGN 489
+E ++ ++K+ + T +S+ + GN
Sbjct: 72 VEILNKEKKAVSPLLLTTTNSSEGLSMGN 100
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 517 ELNEKRRG----LKYELISETGGSHDKRFVMEVEVDGQKF-RGAGPNKKVAKASAALAAL 571
ELN R+ LKY+ + +G HD+RF +V +DG++F G G +KK AK +AA A+
Sbjct: 13 ELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAV 72
Query: 572 EKLFSGPNAANNKKKKIIPQAKGVVNTA 599
E L N +KK + P N++
Sbjct: 73 EIL-------NKEKKAVSPLLLTTTNSS 93
Score = 35.0 bits (79), Expect = 0.23
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTY-EASGPSKKTAKLHVAVKVLQAMGYPTGFDAD 460
L+Y+ L SGP H FT V +DG + E G SKK AK + A K+
Sbjct: 25 LKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAK-NAAAKLA------------ 71
Query: 461 IECMSSDEKSDNESKNETVSSNSSNNTGN 489
+E ++ ++K+ + T +S+ + GN
Sbjct: 72 VEILNKEKKAVSPLLLTTTNSSEGLSMGN 100
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,503,879
Number of Sequences: 37866
Number of extensions: 1242952
Number of successful extensions: 3784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3481
Number of HSP's gapped (non-prelim): 260
length of query: 672
length of database: 18,247,518
effective HSP length: 109
effective length of query: 563
effective length of database: 14,120,124
effective search space: 7949629812
effective search space used: 7949629812
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.