Search of human proteins with 21361728

Search of human proteins with 21361728

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361728 vacuolar protein sorting 53 isoform 2 [Homo
sapiens]
         (670 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361728 vacuolar protein sorting 53 isoform 2 [Homo sapiens]     1338   0.0  
gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens]    1313   0.0  
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          42   0.001
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 34   0.50 
gi|150417975 RhoA/RAC/CDC42 exchange factor isoform 1 [Homo sapi...    32   1.5  
gi|162287076 RhoA/RAC/CDC42 exchange factor isoform 3 [Homo sapi...    32   1.5  
gi|162417982 zinc finger protein 64 isoform d [Homo sapiens]           32   2.5  
gi|40806227 zinc finger protein 64 isoform c [Homo sapiens]            32   2.5  
gi|40806223 zinc finger protein 64 isoform a [Homo sapiens]            32   2.5  
gi|188497618 connector enhancer of kinase suppressor of Ras 1 [H...    32   2.5  
gi|92091575 coiled-coil domain containing 57 [Homo sapiens]            32   2.5  
gi|16418351 coiled-coil domain containing 97 [Homo sapiens]            31   3.2  
gi|50962882 G patch domain containing 8 [Homo sapiens]                 31   4.2  
gi|47519562 reticulon 4 isoform E [Homo sapiens]                       30   5.5  
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       30   5.5  
gi|4557789 norrin precursor [Homo sapiens]                             30   5.5  
gi|5174501 zinc finger protein, subfamily 1A, 1 (Ikaros) [Homo s...    30   7.2  
gi|148746189 multiple PDZ domain protein [Homo sapiens]                30   7.2  
gi|8393009 chromosome 11 open reading frame2 [Homo sapiens]            30   7.2  
gi|40806225 zinc finger protein 64 isoform b [Homo sapiens]            30   7.2  
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              30   7.2  
gi|124286830 zinc finger protein 618 [Homo sapiens]                    30   7.2  
gi|195972900 thromboxane A synthase 1, platelet isoform TXS-II [...    30   9.4  
gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [H...    30   9.4  
gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [H...    30   9.4  
gi|44890059 involucrin [Homo sapiens]                                  30   9.4  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    30   9.4  

>gi|21361728 vacuolar protein sorting 53 isoform 2 [Homo sapiens]
          Length = 670

 Score = 1338 bits (3463), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
           MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN
Sbjct: 1   MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60

Query: 61  IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAKRHLTTSITTL 120
           IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAKRHLTTSITTL
Sbjct: 61  IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAKRHLTTSITTL 120

Query: 121 NHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQT 180
           NHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQT
Sbjct: 121 NHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQT 180

Query: 181 ELGQQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYL 240
           ELGQQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYL
Sbjct: 181 ELGQQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYL 240

Query: 241 VLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELA 300
           VLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELA
Sbjct: 241 VLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELA 300

Query: 301 KIMRTRAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDE 360
           KIMRTRAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDE
Sbjct: 301 KIMRTRAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDE 360

Query: 361 PTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVA 420
           PTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVA
Sbjct: 361 PTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVA 420

Query: 421 DFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYA 480
           DFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYA
Sbjct: 421 DFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYA 480

Query: 481 WKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQL 540
           WKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQL
Sbjct: 481 WKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQL 540

Query: 541 EEKLKEKVDVSLIERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALTAMSKMQWQNVE 600
           EEKLKEKVDVSLIERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALTAMSKMQWQNVE
Sbjct: 541 EEKLKEKVDVSLIERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALTAMSKMQWQNVE 600

Query: 601 HVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPIS 660
           HVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPIS
Sbjct: 601 HVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPIS 660

Query: 661 MVGAEQVRWT 670
           MVGAEQVRWT
Sbjct: 661 MVGAEQVRWT 670


>gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens]
          Length = 832

 Score = 1313 bits (3399), Expect = 0.0
 Identities = 666/696 (95%), Positives = 667/696 (95%), Gaps = 29/696 (4%)

Query: 1   MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
           MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN
Sbjct: 1   MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60

Query: 61  IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQ------------------------- 95
           IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQ                         
Sbjct: 61  IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEK 120

Query: 96  ----VKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 151
               VKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG
Sbjct: 121 SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 180

Query: 152 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 211
           VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD
Sbjct: 181 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 240

Query: 212 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 271
           ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE
Sbjct: 241 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 300

Query: 272 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 331
           KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK
Sbjct: 301 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 360

Query: 332 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 391
           RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI
Sbjct: 361 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 420

Query: 392 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 451
           VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK
Sbjct: 421 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 480

Query: 452 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 511
           CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE
Sbjct: 481 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 540

Query: 512 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 571
           VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS
Sbjct: 541 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 600

Query: 572 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 631
           SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR
Sbjct: 601 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 660

Query: 632 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQV 667
           KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQ+
Sbjct: 661 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQL 696


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 2/109 (1%)

Query: 4   EEELEFVEELEAVLQLTPEV--QLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
           E   E +E L    Q   E   ++A  +V   +  LD A+F +VE   T     Q LA +
Sbjct: 822 ELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAEL 881

Query: 62  DEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAK 110
           ++++   + KI+     I+  +  + N  Q+  ++K+I +++KQ++  K
Sbjct: 882 EKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIK 930


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 6/127 (4%)

Query: 57  SLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAKRHLTTS 116
           SL N+ E  +K     R L +  R + R +T + +   ++KE+  + KQL+   + +  +
Sbjct: 598 SLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQA 657

Query: 117 ITTLNHLHMLAGGVDSLEAMTRRRQYGEV-ANLLQGVMNVLEHFHKYMGIPQIRQLSERV 175
           I  +     + GG  SL   +  R    + +   +G+ +   H        Q+ QL+ R 
Sbjct: 658 IKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLK-----AQVDQLTGRN 712

Query: 176 KAAQTEL 182
           +  + EL
Sbjct: 713 EELRQEL 719


>gi|150417975 RhoA/RAC/CDC42 exchange factor isoform 1 [Homo
           sapiens]
          Length = 580

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 24/133 (18%), Positives = 56/133 (42%), Gaps = 6/133 (4%)

Query: 359 DEPTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRF 418
           D+  P  EE  ++  + ++ +K KA +   + +        +YV       +LG++++ +
Sbjct: 133 DKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYV------DDLGQIVEGY 186

Query: 419 VADFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLRE 478
           +A   AQG P+        V  +   ++ +++   +Q  Q    +P        +   R 
Sbjct: 187 MATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRL 246

Query: 479 YAWKILSGNLPKT 491
           + + +   N PK+
Sbjct: 247 HMYVVYCQNKPKS 259


>gi|162287076 RhoA/RAC/CDC42 exchange factor isoform 3 [Homo
           sapiens]
          Length = 619

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 24/133 (18%), Positives = 56/133 (42%), Gaps = 6/133 (4%)

Query: 359 DEPTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRF 418
           D+  P  EE  ++  + ++ +K KA +   + +        +YV       +LG++++ +
Sbjct: 172 DKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYV------DDLGQIVEGY 225

Query: 419 VADFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLRE 478
           +A   AQG P+        V  +   ++ +++   +Q  Q    +P        +   R 
Sbjct: 226 MATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRL 285

Query: 479 YAWKILSGNLPKT 491
           + + +   N PK+
Sbjct: 286 HMYVVYCQNKPKS 298


>gi|162417982 zinc finger protein 64 isoform d [Homo sapiens]
          Length = 645

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 17/148 (11%)

Query: 320 QRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPK 379
           Q+  N + F+A + SGC LT GT     +  PST  F+ +E  P  +   T +    + +
Sbjct: 38  QQFNNLDAFVAHKQSGCQLT-GT----SAAAPSTVQFVSEETVPATQTQTTTRTITSETQ 92

Query: 380 --KPKAPDNPF-HGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEG- 435
                AP+  F HG          Y+  ES +     +I    A  + + P  P   +  
Sbjct: 93  TITVSAPEFVFEHGY-------QTYLPTESNENQTATVIS-LPAKSRTKKPTTPPAQKRL 144

Query: 436 GAVLPSCADLFVYYKKCMVQCSQLSTGE 463
               P C     Y  K M +  ++ TG+
Sbjct: 145 NCCYPGCQFKTAYGMKDMERHLKIHTGD 172


>gi|40806227 zinc finger protein 64 isoform c [Homo sapiens]
          Length = 679

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 17/148 (11%)

Query: 320 QRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPK 379
           Q+  N + F+A + SGC LT GT     +  PST  F+ +E  P  +   T +    + +
Sbjct: 36  QQFNNLDAFVAHKQSGCQLT-GT----SAAAPSTVQFVSEETVPATQTQTTTRTITSETQ 90

Query: 380 --KPKAPDNPF-HGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEG- 435
                AP+  F HG          Y+  ES +     +I    A  + + P  P   +  
Sbjct: 91  TITVSAPEFVFEHGY-------QTYLPTESNENQTATVIS-LPAKSRTKKPTTPPAQKRL 142

Query: 436 GAVLPSCADLFVYYKKCMVQCSQLSTGE 463
               P C     Y  K M +  ++ TG+
Sbjct: 143 NCCYPGCQFKTAYGMKDMERHLKIHTGD 170


>gi|40806223 zinc finger protein 64 isoform a [Homo sapiens]
          Length = 681

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 17/148 (11%)

Query: 320 QRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPK 379
           Q+  N + F+A + SGC LT GT     +  PST  F+ +E  P  +   T +    + +
Sbjct: 38  QQFNNLDAFVAHKQSGCQLT-GT----SAAAPSTVQFVSEETVPATQTQTTTRTITSETQ 92

Query: 380 --KPKAPDNPF-HGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEG- 435
                AP+  F HG          Y+  ES +     +I    A  + + P  P   +  
Sbjct: 93  TITVSAPEFVFEHGY-------QTYLPTESNENQTATVIS-LPAKSRTKKPTTPPAQKRL 144

Query: 436 GAVLPSCADLFVYYKKCMVQCSQLSTGE 463
               P C     Y  K M +  ++ TG+
Sbjct: 145 NCCYPGCQFKTAYGMKDMERHLKIHTGD 172


>gi|188497618 connector enhancer of kinase suppressor of Ras 1 [Homo
           sapiens]
          Length = 713

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 12/44 (27%), Positives = 26/44 (59%)

Query: 116 SITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHF 159
           ++ +L H  ++ GGV+ L+A++ R Q   + +L +G++     F
Sbjct: 50  AVRSLGHQELILGGVEQLQALSSRLQTENLQSLTEGLLGATHDF 93


>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
          Length = 915

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 20/153 (13%)

Query: 6   ELEFVEELEAVLQLT-PEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANID-- 62
           E   VEEL+   QL   E +L +E+V    D     D +  +Y N  +  E+ L  +D  
Sbjct: 109 EARKVEELQQQQQLAFQEHRLELERVH--SDKNGEIDHHREQYENLKWTLERKLEELDGE 166

Query: 63  ------EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGR-QVKEITRDIKQLDHA------ 109
                 E++ +   K+R+ +   R      +N       +VK + ++++ L  A      
Sbjct: 167 LALQRQELLLEFESKMRKREHEFRLQADNMSNTALSRELKVKLLHKELEALKEAGAKAAE 226

Query: 110 --KRHLTTSITTLNHLHMLAGGVDSLEAMTRRR 140
             +R   T+      L   AG +  LEAM+R R
Sbjct: 227 SLQRAEATNAELERKLQSRAGELQDLEAMSRAR 259


>gi|16418351 coiled-coil domain containing 97 [Homo sapiens]
          Length = 343

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 26/159 (16%)

Query: 132 SLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADF- 190
           +L    R R+Y  +  L+QG     E+F             E+++     L +Q +  + 
Sbjct: 149 TLRTRLRNRRYAALRELIQGG----EYFS-----------DEQMRFRAPLLYEQYIGQYL 193

Query: 191 --EEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQD 248
             EE      T +P  P +  R AC ++N+L    ++  +++ + Q   E     +E ++
Sbjct: 194 TQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEE 253

Query: 249 VAWLDKIDRR-----YAWI---KRQLVDYEEKYGRMFPR 279
               D+ D+R      AW+   + +L+  EE   RM  R
Sbjct: 254 EEDSDEEDQRSGKDSEAWVPDSEERLILREEFTSRMHQR 292


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 29/105 (27%)

Query: 131  DSLEAMTRRRQYGEVANLLQGVMNVLEHFHKY---MGIPQI------------------- 168
            D+LE++    Q G V + L  +   LEHF  Y    G P I                   
Sbjct: 1251 DTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPI 1310

Query: 169  -------RQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPS 206
                    + S+  +AAQ  + QQ+LA   +AFP+     P  P+
Sbjct: 1311 TFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPA 1355


>gi|47519562 reticulon 4 isoform E [Homo sapiens]
          Length = 986

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 4/59 (6%)

Query: 21 PEVQLAIEQVFPSQDPLDRADFNAVEY---INTLFPTEQSL-ANIDEVVNKIRLKIRRL 75
          P V L      PS  PL  A F   EY   ++T+ PTE +L  N+ E   ++  K + L
Sbjct: 19 PSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTL 77


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 4/59 (6%)

Query: 21  PEVQLAIEQVFPSQDPLDRADFNAVEY---INTLFPTEQSL-ANIDEVVNKIRLKIRRL 75
           P V L      PS  PL  A F   EY   ++T+ PTE +L  N+ E   ++  K + L
Sbjct: 225 PSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTL 283


>gi|4557789 norrin precursor [Homo sapiens]
          Length = 133

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 439 LPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLR 477
           L  C+   V   +C   CSQ S  EP+++ +T+ ++  R
Sbjct: 52  LYKCSSKMVLLARCEGHCSQASRSEPLVSFSTVLKQPFR 90


>gi|5174501 zinc finger protein, subfamily 1A, 1 (Ikaros) [Homo
           sapiens]
          Length = 519

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 347 ESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPK 382
           ESPP S  P   DEP P  E+L+T  G     K  +
Sbjct: 16  ESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDR 51


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 20/72 (27%), Positives = 41/72 (56%), Gaps = 5/72 (6%)

Query: 534 LATTQQLEEKLKEKVDVSLIERINLTGEM---DTFSTVISSSIQLLVQDLDAACDPALTA 590
           L   ++L+ KL+E+ DV+  ++++L   +     FS ++S  +Q  VQ L    + A +A
Sbjct: 11  LHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILS--LQTSVQQLKDQVNIATSA 68

Query: 591 MSKMQWQNVEHV 602
            S +++ +V H+
Sbjct: 69  TSNIEYAHVPHL 80


>gi|8393009 chromosome 11 open reading frame2 [Homo sapiens]
          Length = 782

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 37/191 (19%), Positives = 70/191 (36%), Gaps = 36/191 (18%)

Query: 35  DPLDRADFNAVEYINTLF----PTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVG 90
           DPLD  D N   +   ++      E  LA + +    +  +IR LD +++T+V    N  
Sbjct: 56  DPLDPTDLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKF 115

Query: 91  QDGRQ-VKEITRDIKQLDHAKRHLTTSIT-----------TLNHLHMLAGGVDSLEAMTR 138
                 ++++  D ++++     L T++            TL   H     +  + A+ R
Sbjct: 116 ISATDTIRKMKNDFRKMEDEMDRLATNMAVITDFSARISATLQDRHERITKLAGVHALLR 175

Query: 139 RRQ-----------------YGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTE 181
           + Q                 YG+          VL+   +Y  +P  R + +  +     
Sbjct: 176 KLQFLFELPSRLTKCVELGAYGQAVRYQGRAQAVLQ---QYQHLPSFRAIQDDCQVITAR 232

Query: 182 LGQQILADFEE 192
           L QQ+   F E
Sbjct: 233 LAQQLRQRFRE 243


>gi|40806225 zinc finger protein 64 isoform b [Homo sapiens]
          Length = 627

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 5/53 (9%)

Query: 320 QRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEK 372
           Q+  N + F+A + SGC LT GT     +  PST  F+ +E  P  +   T +
Sbjct: 38  QQFNNLDAFVAHKQSGCQLT-GT----SAAAPSTVQFVSEETVPATQTQTTTR 85


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 20/83 (24%), Positives = 42/83 (50%), Gaps = 4/83 (4%)

Query: 467  ALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTIS-SLLKEKEGSEVAKFTLEELCLICN 525
            +L +IFQ    E++   L   +     S   + +  ++L+++EG E+A  +      +C 
Sbjct: 2274 SLNSIFQN--SEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQ 2331

Query: 526  ILSTAEYCLATTQQLEEKLKEKV 548
            ++  A   LA++ +L  K+K K+
Sbjct: 2332 VIIKASSSLASS-ELMRKIKSKI 2353


>gi|124286830 zinc finger protein 618 [Homo sapiens]
          Length = 861

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 16/51 (31%), Positives = 25/51 (49%)

Query: 478 EYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILS 528
           E  WK  +       T++ GLT +S++ EKE   +A+  L  +C     LS
Sbjct: 342 EEKWKPQAQRNSANNTTTSGLTPNSMIPEKERQNIAERLLRVMCADLGALS 392


>gi|195972900 thromboxane A synthase 1, platelet isoform TXS-II
           [Homo sapiens]
          Length = 460

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 15/29 (51%), Positives = 18/29 (62%)

Query: 522 LICNILSTAEYCLATTQQLEEKLKEKVDV 550
           +I N LS A Y LAT    +EKL  +VDV
Sbjct: 346 IITNTLSFATYLLATNPDCQEKLLREVDV 374


>gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 15/29 (51%), Positives = 18/29 (62%)

Query: 522 LICNILSTAEYCLATTQQLEEKLKEKVDV 550
           +I N LS A Y LAT    +EKL  +VDV
Sbjct: 346 IITNTLSFATYLLATNPDCQEKLLREVDV 374


>gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 15/29 (51%), Positives = 18/29 (62%)

Query: 522 LICNILSTAEYCLATTQQLEEKLKEKVDV 550
           +I N LS A Y LAT    +EKL  +VDV
Sbjct: 346 IITNTLSFATYLLATNPDCQEKLLREVDV 374


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 39/188 (20%), Positives = 85/188 (45%), Gaps = 26/188 (13%)

Query: 3   EEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANID 62
           +E +LE +EE E  L+   + +  +E +   +  L   +   ++ +  L   +    +++
Sbjct: 329 QEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQ-LKQLEKQQGQPKHLE 387

Query: 63  EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQVKEITRDIKQLDHAKRHLTTSITTLNH 122
           E   +++  +++ +  ++ +V+ +  + Q  RQV+ + + + QL    +HL      L H
Sbjct: 388 EEEGQLKHLVQQ-EGQLKHLVQQEGQLEQQERQVEHLEQQVGQL----KHLEEQEGQLKH 442

Query: 123 LHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIP-----QIRQLSERVKA 177
           L    G ++  E     +Q G+  N        LE   K + +P     Q++ L +  + 
Sbjct: 443 LEQQQGQLEVPE-----QQVGQPKN--------LEQEEKQLELPEQQEGQVKHLEK--QE 487

Query: 178 AQTELGQQ 185
           AQ EL +Q
Sbjct: 488 AQLELPEQ 495


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 14/47 (29%), Positives = 27/47 (57%), Gaps = 1/47 (2%)

Query: 72   IRRLDDNIRTVVRGQTN-VGQDGRQVKEITRDIKQLDHAKRHLTTSI 117
            ++R + N++  +   T  + + G+ + E+ +  KQLDH K  L TS+
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSL 1548


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,981,174
Number of Sequences: 37866
Number of extensions: 1117782
Number of successful extensions: 3697
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3675
Number of HSP's gapped (non-prelim): 39
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.