Search of human proteins with 21361449

Search of human proteins with 21361449

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
         (477 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361449 solute carrier family 2 (facilitated glucose transpo...   951   0.0  
gi|223029432 solute carrier family 2 (facilitated glucose transp...   358   5e-99
gi|223029430 solute carrier family 2 (facilitated glucose transp...   306   2e-83
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   211   2e-54
gi|23592238 glucose transporter 14 [Homo sapiens]                     202   5e-52
gi|4507011 glucose transporter 4 [Homo sapiens]                       191   2e-48
gi|166795299 solute carrier family 2 (facilitated glucose transp...   185   9e-47
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   180   2e-45
gi|21553331 solute carrier family 2 (facilitated glucose transpo...   180   3e-45
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   153   4e-37
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   150   2e-36
gi|203098995 solute carrier family 2 (facilitated glucose transp...   142   9e-34
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   137   3e-32
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   136   4e-32
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   126   4e-29
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   125   1e-28
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   125   1e-28
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]          121   2e-27
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            79   1e-14
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]            69   1e-11
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    67   3e-11
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]          67   5e-11
gi|11415038 solute carrier family 22 member 3 [Homo sapiens]           65   2e-10
gi|166197673 solute carrier family 22, member 15 [Homo sapiens]        62   9e-10
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    60   3e-09
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    60   3e-09
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    60   3e-09
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...    59   7e-09
gi|31542327 solute carrier family 22, member 16 [Homo sapiens]         55   1e-07
gi|24497490 solute carrier family 22 member 4 [Homo sapiens]           54   2e-07

>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  951 bits (2457), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP 60
           MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
Sbjct: 1   MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP 60

Query: 61  APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV 120
           APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
Sbjct: 61  APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV 120

Query: 121 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE 180
           WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
Sbjct: 121 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE 180

Query: 181 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE 240
           WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
Sbjct: 181 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE 240

Query: 241 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV 300
           QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
Sbjct: 241 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV 300

Query: 301 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS 360
           IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
Sbjct: 301 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS 360

Query: 361 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM 420
           AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
Sbjct: 361 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM 420

Query: 421 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477
           AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
Sbjct: 421 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  358 bits (920), Expect = 5e-99
 Identities = 209/485 (43%), Positives = 291/485 (60%), Gaps = 19/485 (3%)

Query: 6   PEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPA 61
           PE+  P    PG  A  G    +RVFLA FAA LG  SFG+AL Y+SP IP+L+R+  P 
Sbjct: 17  PEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPD 73

Query: 62  PRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW 121
             L  + ASWFG+V TLGAAAGG+    L D  GRKLS++  +VP  AG+A++  A  +W
Sbjct: 74  LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW 133

Query: 122 MLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEW 181
           MLL GR LTG A G+ +   PVY+SEIA P VRG LG+  QLM V G L  Y  G +L W
Sbjct: 134 MLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPW 193

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQG--WEDPPIG- 238
           RWLAV G  P  +M+LL+ FMP +PRFLL++ R +EA+ AL +L G++    WE   I  
Sbjct: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253

Query: 239 --AEQSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEE-AKFKDSSL 293
               QS  +  A  R P + +P  + + +   QQL+G+  ++ Y ++IF+  A       
Sbjct: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKD 313

Query: 294 ASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHV 353
            + +VG +++L   +AAL MD AGR++LL +S  +M  +    G Y          +S  
Sbjct: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTA 373

Query: 354 AISAPV---SAQPVDASVG-LAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVA 409
            + +      AQP+ A  G L  + + +  LFI G+AVGWGPI WLLMSE+ PL  +GVA
Sbjct: 374 GLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVA 433

Query: 410 TGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQ 469
           +G+CVL +WL AF++TK F  ++        F+  +A C+ S++FT  CVPETKG++LEQ
Sbjct: 434 SGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQ 493

Query: 470 ITAHF 474
           I + F
Sbjct: 494 IESFF 498


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  306 bits (785), Expect = 2e-83
 Identities = 191/481 (39%), Positives = 266/481 (55%), Gaps = 73/481 (15%)

Query: 6   PEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPA 61
           PE+  P    PG  A  G    +RVFLA FAA LG  SFG+AL Y+SP IP+L+R+  P 
Sbjct: 17  PEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPD 73

Query: 62  PRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW 121
             L  + ASWFG+V TLGAAAGG+    L D  GRKLS++  +VP  AG+A++  A  +W
Sbjct: 74  LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW 133

Query: 122 MLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEW 181
           MLL GR LTG A G+ +   PVY+SEIA P VRG LG+  QLM V G L  Y  G +L W
Sbjct: 134 MLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPW 193

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQG--WEDPPIG- 238
           RWLAV G  P  +M+LL+ FMP +PRFLL++ R +EA+ AL +L G++    WE   I  
Sbjct: 194 RWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253

Query: 239 --AEQSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEE-AKFKDSSL 293
               QS  +  A  R P + +P  + + +   QQL+G+  ++ Y ++IF+  A       
Sbjct: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKD 313

Query: 294 ASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHV 353
            + +VG +++L   +AAL MD AGR++LL +SG  + +              GP      
Sbjct: 314 DAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSGYAVGW--------------GP------ 353

Query: 354 AISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGIC 413
                           + WL                      LMSE+ PL  +GVA+G+C
Sbjct: 354 ----------------ITWL----------------------LMSEVLPLRARGVASGLC 375

Query: 414 VLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAH 473
           VL +WL AF++TK F  ++        F+  +A C+ S++FT  CVPETKG++LEQI + 
Sbjct: 376 VLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESF 435

Query: 474 F 474
           F
Sbjct: 436 F 436


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  211 bits (536), Expect = 2e-54
 Identities = 151/481 (31%), Positives = 241/481 (50%), Gaps = 51/481 (10%)

Query: 26  VFLAAFAAALGPLSFGFALGYSSPAIPSLQRA----------APPAPRLDDAAASWFGAV 75
           +  A   A +G   FG+  G  +     ++            APP+  L  +  S   A+
Sbjct: 10  LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69

Query: 76  VTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAG---FAVITAAQDVWMLLGGRLLTGL 132
            ++G   G    G  V+R GR+ S+L+ ++  V G     +   A+ V ML+ GRL+ GL
Sbjct: 70  FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129

Query: 133 ACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG--WVL--EWRWLAVLG 188
            CG+ +   P+YI EI+  A+RG  G+  QL +VVGIL+A + G  ++L  E  W  +LG
Sbjct: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189

Query: 189 --CVPPSLMLLLMCFMPETPRFLLTQHRRQE-AMAALRFLWGSEQGWEDPPIGAEQSFHL 245
              +P  L    + F PE+PRFLL   + +E A   L+ LWG++   +D     ++S  +
Sbjct: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249

Query: 246 A---------LLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASV 296
           +         L R     +P II + L   QQLSG+NAV +Y+  IF++A  ++   A++
Sbjct: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATI 309

Query: 297 VVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAIS 356
             GV+  +FT V+  +++RAGRR L ++                     G G  +  +  
Sbjct: 310 GAGVVNTIFTVVSLFLVERAGRRTLHMI---------------------GLGGMAFCSTL 348

Query: 357 APVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLT 416
             VS    D   G++++ +G++ +F+A F +G GPIPW +++E+F    +  A  +   +
Sbjct: 349 MTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCS 408

Query: 417 NWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEG 476
           NW   FLV   F S    L  Y  F + + F I  + FT F VPET+G+T E IT  FEG
Sbjct: 409 NWTSNFLVGLLFPSAAHYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEG 467

Query: 477 R 477
           +
Sbjct: 468 Q 468


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  202 bits (514), Expect = 5e-52
 Identities = 146/481 (30%), Positives = 236/481 (49%), Gaps = 51/481 (10%)

Query: 26  VFLAAFAAALGPLSFGFALGYSSPAIPSLQRA----------APPAPRLDDAAASWFGAV 75
           +  A   A +G   FG+  G  +     ++            APP+  L     S   A+
Sbjct: 34  LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93

Query: 76  VTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAG---FAVITAAQDVWMLLGGRLLTGL 132
            ++G   G    G  V+R GR+ S+L+ ++    G     +   A+ V ML+ GRL+ GL
Sbjct: 94  FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153

Query: 133 ACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL----EWRWLAVLG 188
            CG+ +   P+YI EI+  A+RG  G+  QL +V+GIL+A + G  L    E  W  +LG
Sbjct: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213

Query: 189 --CVPPSLMLLLMCFMPETPRFLLTQHRRQE-AMAALRFLWGSEQGWEDPPIGAEQSFHL 245
              +P  L    +   PE+PRFLL   +++E A   L+ LWG++   +D     ++S  +
Sbjct: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273

Query: 246 A---------LLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASV 296
           +         L R     +P II + L   QQLSG+NAV +Y+  IF++A  +    A++
Sbjct: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATI 333

Query: 297 VVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAIS 356
             GV+  +FT ++  +++RAGRR L ++                     G G  +  +  
Sbjct: 334 SAGVVNTIFTLLSLFLVERAGRRTLHMI---------------------GLGGMAFCSTL 372

Query: 357 APVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLT 416
             VS    +   G++++ +G++ +F+A F +G GPIPW +++E+F    +  A  +   +
Sbjct: 373 MTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCS 432

Query: 417 NWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEG 476
           NW   FLV   F S    L  Y  F + + F I  + FT F VPET+G+T E IT  FEG
Sbjct: 433 NWTSNFLVGLLFPSAAYYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEG 491

Query: 477 R 477
           +
Sbjct: 492 Q 492


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  191 bits (484), Expect = 2e-48
 Identities = 150/498 (30%), Positives = 243/498 (48%), Gaps = 58/498 (11%)

Query: 13  LGPPGGSAPRGR---RVFLAAFAAALGPLSFGFALGYSSPAIPSLQ---------RAAPP 60
           +G   G  P+ R    + LA F+A LG L FG+ +G  +     ++         R  P 
Sbjct: 8   IGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPE 67

Query: 61  APR-LDDAAASWFGAVVTLGAAAGGVLGGWLV----DRAGRKLSLLLCSVPFVAGFAVI- 114
            P  +     +   A+     + GG++  +L+       GRK ++L+ +V  V G +++ 
Sbjct: 68  GPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMG 127

Query: 115 --TAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA 172
              AA    ML+ GR L G   G+ S + P+Y+ EIA   +RG LG+  QL +V+GIL+A
Sbjct: 128 LANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIA 187

Query: 173 Y------LAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFL-LTQHRRQEAMAALRFL 225
                  L G    W  L  L  +P  L L+L+ F PE+PR+L + Q+    A  +L+ L
Sbjct: 188 QVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRL 247

Query: 226 --WGSEQG----WEDPPIGAEQSFHLALLRQPGIY---KPFIIGVSLMAFQQLSGVNAVM 276
             W    G     +D     E+   L+LL+  G     +P II V L   QQLSG+NAV 
Sbjct: 248 TGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVF 307

Query: 277 FYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAF 336
           +Y+ +IFE A     + A++  GV+  +FT V+ L+++RAGRR L +L            
Sbjct: 308 YYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLL------------ 355

Query: 337 GAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLL 396
                    G       AI   V+   ++    ++++++ ++  F+A F +G GPIPW +
Sbjct: 356 ---------GLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFI 406

Query: 397 MSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTL 456
           ++E+F    +  A  +   +NW   F++   F  + E + PY  F L +   +   +FT 
Sbjct: 407 VAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPY-VFLLFAVLLLGFFIFTF 465

Query: 457 FCVPETKGKTLEQITAHF 474
             VPET+G+T +QI+A F
Sbjct: 466 LRVPETRGRTFDQISAAF 483


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  185 bits (469), Expect = 9e-47
 Identities = 139/483 (28%), Positives = 235/483 (48%), Gaps = 59/483 (12%)

Query: 25  RVFLAAFAAALGPLSFGFALGYSSPAIPSLQR----------AAPPAPRLDDAAASWFGA 74
           R+ LA   A LG L FG+  G  +     ++                P       S   A
Sbjct: 11  RLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVA 70

Query: 75  VVTLGAAAGGVLGGWLVDRAGRKLSLLLCSV-PFVA----GFAVITAAQDVWMLLGGRLL 129
           + ++G   G    G  V+R GR+ S+L+ ++  FV+    GF+ +  + +  ML+ GR +
Sbjct: 71  IFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE--MLILGRFI 128

Query: 130 TGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE--------W 181
            G+ CG+ +   P+Y+ E++  A+RG LG+  QL +VVGIL+A + G  L+        W
Sbjct: 129 IGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG--LDSIMGNKDLW 186

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLL-TQHRRQEAMAALRFLWGSEQGWEDPPIGAE 240
             L  +  +P  L  +++ F PE+PRFLL  ++    A + L+ L G+     D     E
Sbjct: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKE 246

Query: 241 QSFH---------LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDS 291
           +S           L L R P   +P +I V L   QQLSG+NAV +Y+ +IFE+A  +  
Sbjct: 247 ESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQP 306

Query: 292 SLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSS 351
             A++  G++   FT V+  +++RAGRR L ++                     G    +
Sbjct: 307 VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLI---------------------GLAGMA 345

Query: 352 HVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATG 411
             AI   ++   ++    +++L++ ++  F+A F VG GPIPW +++E+F    +  A  
Sbjct: 346 GCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIA 405

Query: 412 ICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQIT 471
           +   +NW   F+V   F  + ++  PY  F + +   +   +FT F VPETKG+T ++I 
Sbjct: 406 VAGFSNWTSNFIVGMCFQYVEQLCGPY-VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464

Query: 472 AHF 474
           + F
Sbjct: 465 SGF 467


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  180 bits (457), Expect = 2e-45
 Identities = 124/417 (29%), Positives = 209/417 (50%), Gaps = 41/417 (9%)

Query: 78  LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQ---DVWMLLGGRLLTGLAC 134
           +G       GGWL D  GR  ++L+ ++  + G  ++  ++      +++ GR ++GL C
Sbjct: 106 VGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYC 165

Query: 135 GVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG--WVLE----WRWLAVLG 188
           G+ S + P+YI EIA  A+RG LG+  QL +V GIL++ + G  ++L     W  L  L 
Sbjct: 166 GLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLS 225

Query: 189 CVPPSLMLLLMCFMPETPRFLLTQHRRQ-EAMAALRFLWG--------SEQGWEDPPIGA 239
            V   L  LL+ F PE+PR+L  +   + +A  +L+ L G        +E   E     +
Sbjct: 226 GVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASS 285

Query: 240 EQSFHLALLRQPGIYK-PFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVV 298
           EQ   +  L     Y+ P ++ + L   QQ SG+N + +Y+ +IF+ A       A++ V
Sbjct: 286 EQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGV 345

Query: 299 GVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAP 358
           G + ++FTAV+  ++++AGRR L ++                     G       AI   
Sbjct: 346 GAVNMVFTAVSVFLVEKAGRRSLFLI---------------------GMSGMFVCAIFMS 384

Query: 359 VSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNW 418
           V    ++    ++++++ ++ LF++ F +G GPIPW +++E F    +  A  I   +NW
Sbjct: 385 VGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNW 444

Query: 419 LMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE 475
              F+V   F  + +   PY  F  A     F+ LFT F VPETKGK+ E+I A F+
Sbjct: 445 TCNFIVALCFQYIADFCGPYVFFLFAGVLLAFT-LFTFFKVPETKGKSFEEIAAEFQ 500


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score =  180 bits (456), Expect = 3e-45
 Identities = 142/529 (26%), Positives = 242/529 (45%), Gaps = 84/529 (15%)

Query: 23  GRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAA 82
           G   FL++  AA+  L  G+ LG  S A+  ++     +    +   S     + +GA  
Sbjct: 37  GMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVS----SLVIGALL 92

Query: 83  GGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAP 142
             + GG L+DR GR+ +++L S     G  V+  +    +L+ GR+  G++  ++S+   
Sbjct: 93  ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATC 152

Query: 143 VYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE---WRWLAVLGCVPP--SLMLL 197
           VYI+EIA    RGLL S  +LM+V+GIL AY++ +        W  + G V P   L  +
Sbjct: 153 VYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAI 212

Query: 198 LMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPI-------GAEQSFHLALLRQ 250
            M F+P +PRFL+ + +   A   L  L       E+  +         + SF      +
Sbjct: 213 AMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSK 272

Query: 251 PGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKD---SSLASVVVGVIQVLFTA 307
             +    +IG++L+ F Q++G   ++FYA T+ +   F+    +SLAS  VGV++V+ T 
Sbjct: 273 DNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTI 332

Query: 308 VAALIMDRAGRRLLLVLSGVVMVFSTSAFG---------------AYFKLTQG------- 345
            A L++D  G +  L +   VM  S    G               ++  + Q        
Sbjct: 333 PATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIY 392

Query: 346 GPGN---------------SSHVAISA----------------------------PVSAQ 362
           GPGN               SSH   S                              +   
Sbjct: 393 GPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTD 452

Query: 363 PVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAF 422
           P D    L WL++ S+ +++A F++G GP+PWL++SEIFP  ++G A  +    NW +  
Sbjct: 453 PGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINL 512

Query: 423 LVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQIT 471
           L++  F ++ +++      ++ +   + S+LF +  +PETKG +LEQI+
Sbjct: 513 LISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  153 bits (386), Expect = 4e-37
 Identities = 145/497 (29%), Positives = 228/497 (45%), Gaps = 69/497 (13%)

Query: 19  SAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPS----LQRA------APPAPRLDDAA 68
           S   GR   + A A  +      F  GY+  A+ S    +Q+             ++D  
Sbjct: 7   SMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFP 66

Query: 69  ASWFGAVVT----LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA-------- 116
            +   +V       G   G +L G LV++ GRK +LL  ++     F+++ A        
Sbjct: 67  LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNI-----FSIVPAILMGCSRV 121

Query: 117 AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG 176
           A    +++  RLL G+  GV+S V P+Y+ E+A   +RG LG   QL + VGIL+A + G
Sbjct: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181

Query: 177 W------VLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWG- 227
                  V  W  L  L  VP +L LLL+ F PE+PR+LL Q ++ EA A  AL+ L G 
Sbjct: 182 LRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQ-KKDEAAAKKALQTLRGW 240

Query: 228 -------SEQGWEDPPIGAEQSFH-LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYA 279
                  +E   ED    A      L L R   +    +  + LM  QQLSGVNA+ +YA
Sbjct: 241 DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA 300

Query: 280 ETIFEEAKFKDSSLASVV--VGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG 337
           + I+  A   +  +  V    G + V+ T  A  +++  GRRLLL+L   + + +     
Sbjct: 301 DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL- 359

Query: 338 AYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLM 397
                       ++ +A+   VS  P        ++++  +  ++ G A+G  PIP LL+
Sbjct: 360 ------------TAALALQDTVSWMP--------YISIVCVISYVIGHALGPSPIPALLI 399

Query: 398 SEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLF 457
           +EIF    +  A  +    +WL  F V   F  + E L PY +F + +  C+ + ++   
Sbjct: 400 TEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY-SFIVFAVICLLTTIYIFL 458

Query: 458 CVPETKGKTLEQITAHF 474
            VPETK KT  +I   F
Sbjct: 459 IVPETKAKTFIEINQIF 475


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  150 bits (379), Expect = 2e-36
 Identities = 126/429 (29%), Positives = 205/429 (47%), Gaps = 59/429 (13%)

Query: 78  LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA--------AQDVWMLLGGRLL 129
           LG   G +L G LVD  GRK +LL+ ++     FA+I A        A+   +++  R++
Sbjct: 86  LGGLLGSLLVGLLVDSCGRKGTLLINNI-----FAIIPAILMGVSKVAKAFELIVFSRVV 140

Query: 130 TGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYL------AGWVLEWRW 183
            G+  G++    P+Y+ E+A   +RG++G+  ++ V+VG+ LA +       G    W  
Sbjct: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200

Query: 184 LAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWGS---EQGWEDPPIG 238
           L  L  VP  L LL + F PE+PR+ L Q +  EA A  ALR L G    E   ED    
Sbjct: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQ-KGDEATARQALRRLRGHTDMEAELEDMRAE 259

Query: 239 AEQS--------FHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFK- 289
           A            HL  LR   +    +  + LMA QQLSG+NA+ +YA+TI+  A  + 
Sbjct: 260 ARAERAEGHLSVLHLCALRS--LRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317

Query: 290 -DSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPG 348
             S   +V  GV+ ++ T  +A++++R GRR LL+                      G G
Sbjct: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLL---------------------AGYG 356

Query: 349 NSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGV 408
                 +   V     +    L++L +  +  +IAG ++G  P+P ++ +EIF    +  
Sbjct: 357 ICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRA 416

Query: 409 ATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLE 468
           A  +    +WL  F++   F S+ E +  Y +F + +  C+ + ++    +PETKGKT  
Sbjct: 417 AFMVDGAVHWLTNFIIGFLFPSIQEAIGAY-SFIIFAGICLLTAIYIYVVIPETKGKTFV 475

Query: 469 QITAHFEGR 477
           +I   F  R
Sbjct: 476 EINRIFAKR 484


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score =  142 bits (357), Expect = 9e-34
 Identities = 101/335 (30%), Positives = 158/335 (47%), Gaps = 27/335 (8%)

Query: 26  VFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGV 85
           V++ A  +ALG   FG+  G  S A+  L+R         +   S       + A AGG 
Sbjct: 81  VYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGA 140

Query: 86  LGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYI 145
           L G      GR+ ++LL S  F AG AV+ AA +   LL GRL+ GL  G+AS+  PVYI
Sbjct: 141 LNGVF----GRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYI 196

Query: 146 SEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE------WRWLAVLGCVPPSLMLLLM 199
           +E++ P +RG L +   L +  G   A +            WR++  L  VP  +     
Sbjct: 197 AEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGF 256

Query: 200 CFMPETPRFLLTQHRRQEAMAALRFLWGSEQ------------GWEDPPIGAEQSFHLAL 247
            F+PE+PR+L+ + + Q+A   L  + G++               E+  +G+       +
Sbjct: 257 LFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRM 316

Query: 248 LRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLA---SVVVGVIQVL 304
           L  P   +  I+G  L  FQQLSG+N +M+Y+ TI + +  +D  LA   + V      +
Sbjct: 317 LSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFI 376

Query: 305 FTAVAALIMDRAGRRLLLV--LSGVVMVFSTSAFG 337
           FT V   ++++ GRR L    L+G  +     A G
Sbjct: 377 FTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALG 411



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 42/107 (39%), Positives = 60/107 (56%)

Query: 371 AWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSS 430
           +W A+  + L++  FA G GP+PW + SEI+PL  +          NW+   LV+  F  
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565

Query: 431 LMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477
             E L  YGAF+L + F    +LF   C+PETKGK LE+I + F+ R
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  137 bits (344), Expect = 3e-32
 Identities = 138/518 (26%), Positives = 219/518 (42%), Gaps = 79/518 (15%)

Query: 14  GPPG------------GSAPRGRR-------VFLAAFAAALGP-LSFGFALGYSSPAIPS 53
           GPPG               P GRR       + +A+ A A G    +G+ L   +   P 
Sbjct: 25  GPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPY 84

Query: 54  LQ---------RAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLS---LL 101
           ++         R   P   +D    +   +V     A GG++G  +V   G+ L     L
Sbjct: 85  IKAFYNESWERRHGRP---IDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTL 141

Query: 102 LCSVPFVAGFAVITA----AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLL 157
           L +  F    A++ A    A    ML+ GR + G+  GVA  V P+Y+SEI+   +RG L
Sbjct: 142 LANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSL 201

Query: 158 GSCVQLMVVVGIL------LAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLT 211
           G    + + +G+       L  L G    W +L  +  VP  + LL + F+P++PR+LL 
Sbjct: 202 GQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLL 261

Query: 212 Q-HRRQEAMAALR-FLWGSEQGWEDPPIGAEQSFH--------LALLRQPGIYKPFIIGV 261
           + H    A+ A + FL  ++   E   + AE            L LLR P +    +  +
Sbjct: 262 EKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321

Query: 262 SLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVV--GVIQVLFTAVAALIMDRAGRR 319
             MA  QL G+NA+ FY  +IF +A    + +  V +  G I+ L    + L+++  GRR
Sbjct: 322 VTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRR 381

Query: 320 LLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMC 379
            LL+                     GG G       +  ++    D +  + +L++  + 
Sbjct: 382 PLLI---------------------GGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGIL 420

Query: 380 LFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG 439
             IA F  G G IP++L  E F    +  A  I    NWL  F V   F  + + L  Y 
Sbjct: 421 AIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTY- 479

Query: 440 AFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477
            F + +  CI   ++  F +PETK +T  +I+  F  R
Sbjct: 480 CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  136 bits (343), Expect = 4e-32
 Identities = 119/422 (28%), Positives = 189/422 (44%), Gaps = 47/422 (11%)

Query: 81  AAGGVLGGWLVDRAGRKLS---LLLCSVPFVAGFAVITA----AQDVWMLLGGRLLTGLA 133
           A GG++G  +V   G+ L     LL +  F    A++ A    A    ML+ GR + G+ 
Sbjct: 89  AIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID 148

Query: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWVLEWRWLAVL 187
            GVA  V P+Y+SEI+   +RG LG    + + +G+       L  L G    W +L  +
Sbjct: 149 GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGV 208

Query: 188 GCVPPSLMLLLMCFMPETPRFLLTQ-HRRQEAMAALR-FLWGSEQGWEDPPIGAEQSFH- 244
             VP  + LL + F+P++PR+LL + H    A+ A + FL  ++   E   + AE     
Sbjct: 209 IVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQR 268

Query: 245 -------LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVV 297
                  L LLR P +    +  +  MA  QL G+NA+ FY  +IF +A    + +  V 
Sbjct: 269 SIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVT 328

Query: 298 V--GVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAI 355
           +  G I+ L    + L+++  GRR LL+                     GG G       
Sbjct: 329 LSTGGIETLAAVFSGLVIEHLGRRPLLI---------------------GGFGLMGLFFG 367

Query: 356 SAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVL 415
           +  ++    D +  + +L++  +   IA F  G G IP++L  E F    +  A  I   
Sbjct: 368 TLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGT 427

Query: 416 TNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE 475
            NWL  F V   F  + + L  Y  F + +  CI   ++  F +PETK +T  +I+  F 
Sbjct: 428 VNWLSNFAVGLLFPFIQKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS 486

Query: 476 GR 477
            R
Sbjct: 487 KR 488


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  126 bits (317), Expect = 4e-29
 Identities = 133/506 (26%), Positives = 220/506 (43%), Gaps = 74/506 (14%)

Query: 7   EETQPLLGPPGGSAPRGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------R 56
           +E +P L P   +  +GR + L   AA +G    FG+ L   +     +Q         R
Sbjct: 3   DELEPSLRPR--TQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQAR 60

Query: 57  AAPPAPRLDDAAASWFGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAV 113
              P P  D      +  +V+L   G   G +L G L    GRK SLL+ ++ FV   A+
Sbjct: 61  TGEPLP--DHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAI 117

Query: 114 ITA----AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGI 169
           +      A    M++ GRLL G+  GV+  + P+Y+ E A   +RG +     +   +GI
Sbjct: 118 LFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGI 177

Query: 170 L------LAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAAL 222
           +      L  L G    W  L     VP +L L  +  +PE+PR+LL      EA +AAL
Sbjct: 178 VMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 237

Query: 223 RFLWGS-EQGWEDPPIGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQ 267
           R L GS +   E   +  E++               H AL RQ  +    ++G ++    
Sbjct: 238 RRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM---- 291

Query: 268 QLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLS 325
           +L G ++V  YA ++F +A   ++ +   ++G    ++L   V+ ++++R GRR+LL+  
Sbjct: 292 ELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGG 351

Query: 326 GVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGF 385
             +M    S F     L    P                        +LA+  +  FI  F
Sbjct: 352 YSLMTCWGSIFTVALCLQSSFPWT---------------------LYLAMACIFAFILSF 390

Query: 386 AVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLAS 445
            +G   +  +L +E+F    +  A  +C    W+M  LV   F  +ME L  +  +    
Sbjct: 391 GIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFL 449

Query: 446 AFCIFSVLFTLFCVPETKGKTLEQIT 471
             C+   ++T   +PETKGKT ++I+
Sbjct: 450 GVCVCGAIYTGLFLPETKGKTFQEIS 475


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  125 bits (313), Expect = 1e-28
 Identities = 129/491 (26%), Positives = 213/491 (43%), Gaps = 72/491 (14%)

Query: 22  RGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------RAAPPAPRLDDAAASW 71
           +GR + L   AA +G    FG+ L   +     +Q         R   P P  D      
Sbjct: 9   QGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLP--DHLVLLM 66

Query: 72  FGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA----AQDVWMLL 124
           +  +V+L   G   G +L G L    GRK SLL+ ++ FV   A++      A    M++
Sbjct: 67  WSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAILFGFSRKAGSFEMIM 125

Query: 125 GGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWV 178
            GRLL G+  GV+  + P+Y+ E A   +RG +     +   +GI+      L  L G  
Sbjct: 126 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 185

Query: 179 LEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAALRFLWGS-EQGWEDPP 236
             W  L     VP +L L  +  +PE+PR+LL      EA +AALR L GS +   E   
Sbjct: 186 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 245

Query: 237 IGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETI 282
           +  E++               H AL RQ  +    ++G ++    +L G ++V  YA ++
Sbjct: 246 LEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM----ELCGNDSVYAYASSV 299

Query: 283 FEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYF 340
           F +A   ++ +   ++G    ++L   V+ ++++R GRR+LL+    +M    S F    
Sbjct: 300 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 359

Query: 341 KLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEI 400
            L    P                        +LA+  +  FI  F +G   +  +L +E+
Sbjct: 360 CLQSSFPWT---------------------LYLAMACIFAFILSFGIGPAGVTGILATEL 398

Query: 401 FPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVP 460
           F    +  A  +C    W+M  LV   F  +ME L  +  +      C+   ++T   +P
Sbjct: 399 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLP 457

Query: 461 ETKGKTLEQIT 471
           ETKGKT ++I+
Sbjct: 458 ETKGKTFQEIS 468


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  125 bits (313), Expect = 1e-28
 Identities = 129/491 (26%), Positives = 213/491 (43%), Gaps = 72/491 (14%)

Query: 22  RGRRVFLAAFAAALG-PLSFGFALGYSSPAIPSLQ---------RAAPPAPRLDDAAASW 71
           +GR + L   AA +G    FG+ L   +     +Q         R   P P  D      
Sbjct: 12  QGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLP--DHLVLLM 69

Query: 72  FGAVVTL---GAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA----AQDVWMLL 124
           +  +V+L   G   G +L G L    GRK SLL+ ++ FV   A++      A    M++
Sbjct: 70  WSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAILFGFSRKAGSFEMIM 128

Query: 125 GGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWV 178
            GRLL G+  GV+  + P+Y+ E A   +RG +     +   +GI+      L  L G  
Sbjct: 129 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 188

Query: 179 LEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA-MAALRFLWGS-EQGWEDPP 236
             W  L     VP +L L  +  +PE+PR+LL      EA +AALR L GS +   E   
Sbjct: 189 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 248

Query: 237 IGAEQSF--------------HLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETI 282
           +  E++               H AL RQ  +    ++G ++    +L G ++V  YA ++
Sbjct: 249 LEEERAACQGCRARRPWELFQHRALRRQ--VTSLVVLGSAM----ELCGNDSVYAYASSV 302

Query: 283 FEEAKFKDSSLASVVVGV--IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYF 340
           F +A   ++ +   ++G    ++L   V+ ++++R GRR+LL+    +M    S F    
Sbjct: 303 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 362

Query: 341 KLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEI 400
            L    P                        +LA+  +  FI  F +G   +  +L +E+
Sbjct: 363 CLQSSFPWT---------------------LYLAMACIFAFILSFGIGPAGVTGILATEL 401

Query: 401 FPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVP 460
           F    +  A  +C    W+M  LV   F  +ME L  +  +      C+   ++T   +P
Sbjct: 402 FDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF-LYVPFLGVCVCGAIYTGLFLP 460

Query: 461 ETKGKTLEQIT 471
           ETKGKT ++I+
Sbjct: 461 ETKGKTFQEIS 471


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score =  121 bits (303), Expect = 2e-27
 Identities = 101/321 (31%), Positives = 150/321 (46%), Gaps = 26/321 (8%)

Query: 28  LAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLG 87
           L A  + LG L+FG+ L   S A+  LQ        L      +    + LGA    ++G
Sbjct: 10  LCASVSLLGGLTFGYELAVISGALLPLQLDFG----LSCLEQEFLVGSLLLGALLASLVG 65

Query: 88  GWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISE 147
           G+L+D  GRK ++L  ++  +AG   +  A  +  L+ GR + G A  ++S+   +Y+SE
Sbjct: 66  GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125

Query: 148 IAYPAVRGLLGSCVQLMVVVGILLAY-----LAGWVLEWRWLAVLGCVPPSLMLLLMCFM 202
           +  P  RG+L S  +  + VGILL+Y     LAG    WR +      P  L  L + F+
Sbjct: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185

Query: 203 PETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIG---AEQSFHLALLRQPGIYKPFII 259
           P       T H+    +          QG E P +G      SF      +  +     +
Sbjct: 186 PAGTDETAT-HKDLIPL----------QGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTV 234

Query: 260 GVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS---LASVVVGVIQVLFTAVAALIMDRA 316
           G+ L+ FQQL+G   V+ YA TIF    F   S   LASV +G ++V  T  A  ++DRA
Sbjct: 235 GLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRA 294

Query: 317 GRRLLLVLSGVVMVFSTSAFG 337
           GRR LL+    +M  S S  G
Sbjct: 295 GRRALLLAGCALMALSVSGIG 315



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 2/135 (1%)

Query: 345 GGPGNSSHVAISAPVSAQPVDAS--VGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFP 402
           G P     +A+S+ +   P+ A     L W A+  + +F++ F+ G+GP+ WL++SEI+P
Sbjct: 381 GDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYP 440

Query: 403 LHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPET 462
           + ++G A   C   NW     ++  F  L+  +     F L     +  + F    VPET
Sbjct: 441 VEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPET 500

Query: 463 KGKTLEQITAHFEGR 477
           KG++L +I   F+ R
Sbjct: 501 KGQSLAEIDQQFQKR 515


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 98/427 (22%), Positives = 173/427 (40%), Gaps = 71/427 (16%)

Query: 68  AASW----FGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCS-VPFVAGFAVITAAQDVWM 122
           A SW    F + V +G   G +  G++ DR GRKL LL    +   AG  +  +    WM
Sbjct: 144 ANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWM 203

Query: 123 LLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL-LAYLAGWVLEW 181
           L+  RL+ GL      L+  + I+E      R  +G   Q+   VG+L LA +A  +  W
Sbjct: 204 LIF-RLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHW 262

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQ 241
           RWL     +P    LL    +PE+PR+L++Q++  EAM  ++ +  +++  +  P   ++
Sbjct: 263 RWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHI--AKKNGKSLPASLQR 320

Query: 242 SFHLALLRQPG--IYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVV- 298
              L L  + G  +   F+  V     ++ + +    ++  ++  +       LA   + 
Sbjct: 321 ---LRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIY 377

Query: 299 ------GVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSH 352
                  +++     +  L +DR GRR     S   MV   +   + F      PG+   
Sbjct: 378 LDFFYSALVEFPAAFMIILTIDRIGRRYPWAASN--MVAGAACLASVFI-----PGD--- 427

Query: 353 VAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI 412
                            L WL +   CL   G  + +  I  L+ +E++P  ++ +   I
Sbjct: 428 -----------------LQWLKIIISCLGRMGITMAY-EIVCLVNAELYPTFIRNLGVHI 469

Query: 413 CVLTNWLMAFLVTKEFSSLMEVLRPYGAF-----WLASAFCIFSVL-----FTLFCVPET 462
           C                 +  ++ P+  +     WL     +F VL       +  +PET
Sbjct: 470 C------------SSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPET 517

Query: 463 KGKTLEQ 469
           KGK L +
Sbjct: 518 KGKALPE 524


>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
          Length = 727

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 21/181 (11%)

Query: 64  LDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAA--QDVW 121
           + ++ + W G++V LG   G    G L D+ GRK SLL+C    V GF    ++  Q   
Sbjct: 185 IPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICM--SVNGFFAFLSSFVQGYG 242

Query: 122 MLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL-- 179
             L  RLL+G   G A      Y +E+     RG   S + +  ++G + A    W +  
Sbjct: 243 FFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIP 302

Query: 180 ---------------EWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRF 224
                           WR   ++  +P    ++ + FMPE+PRFLL   +  EA   L+ 
Sbjct: 303 HYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKL 362

Query: 225 L 225
           +
Sbjct: 363 I 363


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 102/429 (23%), Positives = 171/429 (39%), Gaps = 75/429 (17%)

Query: 68  AASW----FGAVVTLGAAAGGVLGGWLVDRAGRKLSLL-LCSVPFVAGFAVITAAQDVWM 122
           A SW    F + +  G   G +  G+  DR GRKL LL    V  V+G  +  +   + M
Sbjct: 143 ADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSM 202

Query: 123 LLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL-LAYLAGWVLEW 181
           LL  RLL GL      +     I+E      R  +    Q+   VG++ L  LA  +  W
Sbjct: 203 LLF-RLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHW 261

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPP----- 236
           RWL +   +P  L LL    +PE+PR+LL+Q R  EA+  +  +  +++  + PP     
Sbjct: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHI--AQKNGKLPPADLKM 319

Query: 237 IGAEQSF-------HLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFK 289
           +  E+            L R P + K   I         L   ++V++    +   A   
Sbjct: 320 LSLEEDVTEKLSPSFADLFRTPRLRKRTFI------LMYLWFTDSVLYQGLILHMGATSG 373

Query: 290 DSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGN 349
           +  L  +   ++++    +A + +DR GR   + +S +                      
Sbjct: 374 NLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNL---------------------- 411

Query: 350 SSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKG-- 407
                ++       +  S  L WL +  MC+   G  +    I  L+ +E++P  V+   
Sbjct: 412 -----LAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMI-CLVNAELYPTFVRNLG 465

Query: 408 --VATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTL-----FCVP 460
             V + +C +   +  F+V +    L EV       W A    +F+VL  L       +P
Sbjct: 466 VMVCSSLCDIGGIITPFIVFR----LREV-------WQALPLILFAVLGLLAAGVTLLLP 514

Query: 461 ETKGKTLEQ 469
           ETKG  L +
Sbjct: 515 ETKGVALPE 523


>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
          Length = 683

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 65/254 (25%), Positives = 109/254 (42%), Gaps = 26/254 (10%)

Query: 23  GRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAA 82
           GR  ++  F   L  ++ G  +   S A+PS ++       L  +     G +V LG  A
Sbjct: 105 GRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMC----LSSSKKGMLGMIVYLGMMA 160

Query: 83  GGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA-AQDVWMLLGGRLLTGLACGVASLVA 141
           G  + G L D+ GRK  +L  S+   A FA +++  Q     L  RL++G+  G A  + 
Sbjct: 161 GAFILGGLADKLGRK-RVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIV 219

Query: 142 PVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL-----------------EWRWL 184
             Y SE      RG   S + +  + G L A    W +                  WR  
Sbjct: 220 FAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVF 279

Query: 185 AVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFH 244
            ++  +P ++ ++ + FMPE+PRFLL   +  EA   L+ +  +    +  P   E+ F 
Sbjct: 280 VIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTP---EKVFT 336

Query: 245 LALLRQPGIYKPFI 258
           ++ ++ P     FI
Sbjct: 337 VSNIKTPKQMDEFI 350


>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
          Length = 556

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 94/416 (22%), Positives = 171/416 (41%), Gaps = 67/416 (16%)

Query: 74  AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
           A++ LG   G    G+  DR GR +  LL  +       V+  A +  + +  R L G+ 
Sbjct: 159 AILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVF 218

Query: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL-LAYLAGWVLEWRWLAVLGCVPP 192
                +   V ++EI     R ++G  +Q+   +GI+ L  +A ++  W+ + +   +P 
Sbjct: 219 GKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPS 278

Query: 193 SLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWG----------SEQGWEDPPIGAEQS 242
            L LL    +PE+PR+L+T+ +  +A+  LR +            SE    D  + +  S
Sbjct: 279 FLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEV-SNPS 337

Query: 243 FHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQ 302
           F L L+R P + K  +I    + F   +  +AV++    +       +  +   + GV++
Sbjct: 338 F-LDLVRTPQMRKCTLI----LMFAWFT--SAVVYQGLVMRLGIIGGNLYIDFFISGVVE 390

Query: 303 VLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQ 362
           +    +  L ++R GRRL    S +V                   G +  V    P    
Sbjct: 391 LPGALLILLTIERLGRRLPFAASNIV------------------AGVACLVTAFLP---- 428

Query: 363 PVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVK----GVATGICVLTNW 418
                 G+AWL      L   G  + +  I +L+ SE++P  ++     + +G+C     
Sbjct: 429 -----EGIAWLRTTVATLGRLGITMAF-EIVYLVNSELYPTTLRNFGVSLCSGLCDFGGI 482

Query: 419 LMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTL-----FCVPETKGKTLEQ 469
           +  FL+ +             A WL     IF +L ++       +PETKG  L +
Sbjct: 483 IAPFLLFR-----------LAAVWLELPLIIFGILASICGGLVMLLPETKGIALPE 527


>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
          Length = 547

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 55/158 (34%), Positives = 77/158 (48%), Gaps = 7/158 (4%)

Query: 67  AAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLG- 125
           AA+S+F + V +G  + G L     DR GRK  + L        FA+       +     
Sbjct: 113 AASSFFFSGVFVGVISFGQLS----DRFGRK-KVYLTGFALDILFAIANGFSPSYEFFAV 167

Query: 126 GRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE-WRWL 184
            R L G+  G  SLVA V ++E    A   L GS   L   VGI    L G+ +  WR L
Sbjct: 168 TRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTL 227

Query: 185 AVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAAL 222
           A+L  +  +++ LL  F+PE+PR+L +Q R  EA  AL
Sbjct: 228 AILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEAL 265


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 53/158 (33%), Positives = 75/158 (47%), Gaps = 7/158 (4%)

Query: 68  AASW----FGAVVTLGAAAGGVLGGWLVDRAGRKLSLL-LCSVPFVAGFAVITAAQDVWM 122
           A SW    F + +  G   G +  G+  DR GRKL LL    V  V+G  +  +   + M
Sbjct: 143 ADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSM 202

Query: 123 LLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL-LAYLAGWVLEW 181
           LL  RLL GL      +     I+E      R  +    Q+   VG++ L  LA  +  W
Sbjct: 203 LLF-RLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHW 261

Query: 182 RWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAM 219
           RWL +   +P  L LL    +PE+PR+LL+Q R  EA+
Sbjct: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 51/159 (32%), Positives = 84/159 (52%), Gaps = 11/159 (6%)

Query: 64  LDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWML 123
           L+ AA+++F A V +GA A G    +L DR GR+  LL+  V  +       A+    M 
Sbjct: 143 LNRAASTFFFAGVLVGAVAFG----YLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 198

Query: 124 LGGRLLTGLA-CGVASLVAPVYIS--EIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL- 179
              R LTG A  G   +V P+ +   ++ +  V G+L S        G++L  L G+++ 
Sbjct: 199 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW---TGGVMLLALVGYLIR 255

Query: 180 EWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA 218
           +WRWL +   +P +  +L + ++PE+ R+LLTQ   +EA
Sbjct: 256 DWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEA 294


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 51/159 (32%), Positives = 84/159 (52%), Gaps = 11/159 (6%)

Query: 64  LDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWML 123
           L+ AA+++F A V +GA A G    +L DR GR+  LL+  V  +       A+    M 
Sbjct: 141 LNRAASTFFFAGVLVGAVAFG----YLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 196

Query: 124 LGGRLLTGLA-CGVASLVAPVYIS--EIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL- 179
              R LTG A  G   +V P+ +   ++ +  V G+L S        G++L  L G+++ 
Sbjct: 197 AITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW---TGGVMLLALVGYLIR 253

Query: 180 EWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEA 218
           +WRWL +   +P +  +L + ++PE+ R+LLTQ   +EA
Sbjct: 254 DWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEA 292


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 27/180 (15%)

Query: 19  SAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPS----LQRA------APPAPRLDDAA 68
           S   GR   + A A  +      F  GY+  A+ S    +Q+             ++D  
Sbjct: 7   SMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFP 66

Query: 69  ASWFGAVVT----LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA-------- 116
            +   +V       G   G +L G LV++ GRK +LL  ++     F+++ A        
Sbjct: 67  LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNI-----FSIVPAILMGCSRV 121

Query: 117 AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG 176
           A    +++  RLL G+  GV+S V P+Y+ E+A   +RG LG   QL + VGIL+A + G
Sbjct: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181


>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
          Length = 577

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 96/410 (23%), Positives = 157/410 (38%), Gaps = 62/410 (15%)

Query: 79  GAAAGGVLGGWLVDRAGRKLSLLLCSVP-FVAGFAVITAAQDVWMLLGGRLLTGLACGVA 137
           G   G V  G+  DR GR++ L   S   F+ G A   A  D +  +  R    +     
Sbjct: 164 GVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAV-DYYTFMAARFFLAMVASGY 222

Query: 138 SLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLL 197
            +V  VY+ E      R      +     VG LL  L G+++   WL  +     ++  +
Sbjct: 223 LVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFI 282

Query: 198 LMCF-MPETPRFLLTQHRRQEAMAALRFL--WGSE-------------QGWEDPPIGAEQ 241
           L C+ +PETP +LL++ R +EA   +  +  W                QG         Q
Sbjct: 283 LCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQ 342

Query: 242 SFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVI 301
             +L+ L          + V L+ F       ++ FY+ ++       +  L   ++GV+
Sbjct: 343 KHNLSYLFYNWSITKRTLTVWLIWF-----TGSLGFYSFSLNSVNLGGNEYLNLFLLGVV 397

Query: 302 QVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSA 361
           ++       + MD+ GRR +L  S   +  S  A G    + Q       H  +      
Sbjct: 398 EIPAYTFVCIAMDKVGRRTVLAYS---LFCSALACGVVMVIPQ------KHYILGV---- 444

Query: 362 QPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATG----ICVLTN 417
             V A VG           F  G A G   + +L  +E++P  V+ +A G    +C L +
Sbjct: 445 --VTAMVG----------KFAIGAAFG---LIYLYTAELYPTIVRSLAVGSGSMVCRLAS 489

Query: 418 WLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTL 467
            L  F V  + SS+   +             + S + TL  +PET GK L
Sbjct: 490 ILAPFSV--DLSSIWIFIPQL----FVGTMALLSGVLTL-KLPETLGKRL 532


>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
          Length = 551

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 95/421 (22%), Positives = 171/421 (40%), Gaps = 83/421 (19%)

Query: 78  LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVW-MLLGGRLLTGLACGV 136
           +G   G  + G L DR GRK ++L  ++    GF+ +      W M     ++ G+    
Sbjct: 151 VGVLLGSFVSGQLSDRFGRK-NVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQIS 209

Query: 137 ASLVAPVYISEIAYPAVR---GLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPS 193
             +VA +  +EI   +VR     LG C     V  +LL   A ++ +WR L +   VP  
Sbjct: 210 NYVVAFILGTEILGKSVRIIFSTLGVCT-FFAVGYMLLPLFAYFIRDWRMLLLALTVPGV 268

Query: 194 LMLLLMCFMPETPRFLLTQHRRQEA------------MAALRFLWGSEQGWEDPPIGAEQ 241
           L + L  F+PE+PR+L++Q R +EA            +A    ++ S +  E  P+  ++
Sbjct: 269 LCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVE--ELNPLKQQK 326

Query: 242 SFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVI 301
           +F L L R   I    I+ + L        + +V ++A ++       D+ L   +  +I
Sbjct: 327 AFILDLFRTRNIAIMTIMSLLLWM------LTSVGYFALSLDAPNLHGDAYLNCFLSALI 380

Query: 302 QVLFTAVAALIMDRAGRRLL----LVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISA 357
           ++     A L++    RR +    L   G V++F                          
Sbjct: 381 EIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLF-------------------------- 414

Query: 358 PVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTN 417
            +   PVD      +L++G + L   G    +  + ++  +E++P  V+ +A G      
Sbjct: 415 -IQLVPVD----YYFLSIGLVMLGKFGITSAFSML-YVFTAELYPTLVRNMAVG------ 462

Query: 418 WLMAFLVTKEFSSLMEVLRPY----GAFWLASAFCIFSVLFTLFCV-----PETKGKTLE 468
                 VT   S +  ++ PY    GA+     + +   L  L  +     PE+ G TL 
Sbjct: 463 ------VTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLP 516

Query: 469 Q 469
           +
Sbjct: 517 E 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,442,622
Number of Sequences: 37866
Number of extensions: 822392
Number of successful extensions: 3614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 3432
Number of HSP's gapped (non-prelim): 113
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.