Guide to the Human Genome
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Search of human proteins with 213511012

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|213511012 B-cell receptor-associated protein 31 isoform b
[Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom...   471   e-133
gi|213511508 B-cell receptor-associated protein 31 isoform a [Ho...   471   e-133
gi|213511012 B-cell receptor-associated protein 31 isoform b [Ho...   471   e-133
gi|56549093 B-cell receptor-associated protein BAP29 isoform a [...   224   4e-59
gi|56549091 B-cell receptor-associated protein BAP29 isoform b [...   224   4e-59
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    48   9e-06
gi|212276088 leucine rich repeat (in FLII) interacting protein 1...    44   1e-04
gi|212276078 leucine rich repeat (in FLII) interacting protein 1...    44   1e-04
gi|55770834 centromere protein F [Homo sapiens]                        42   5e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    42   6e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           41   8e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    40   0.002
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       40   0.002
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       40   0.002
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        40   0.002
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        40   0.002
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    40   0.002
gi|38044112 restin isoform b [Homo sapiens]                            40   0.002
gi|4506751 restin isoform a [Homo sapiens]                             40   0.002
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    39   0.003
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    39   0.003
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    39   0.003
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    39   0.003
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    39   0.003
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    39   0.003
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       39   0.003
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    39   0.003
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]            39   0.004
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    39   0.004
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]            39   0.004

>gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo
           sapiens]
          Length = 246

 Score =  471 bits (1213), Expect = e-133
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
           MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV
Sbjct: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60

Query: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
           LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV
Sbjct: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
           TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE
Sbjct: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180

Query: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240
           NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP
Sbjct: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240

Query: 241 MDKKEE 246
           MDKKEE
Sbjct: 241 MDKKEE 246


>gi|213511508 B-cell receptor-associated protein 31 isoform a [Homo
           sapiens]
          Length = 313

 Score =  471 bits (1213), Expect = e-133
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
           MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV
Sbjct: 68  MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127

Query: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
           LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV
Sbjct: 128 LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 187

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
           TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE
Sbjct: 188 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 247

Query: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240
           NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP
Sbjct: 248 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 307

Query: 241 MDKKEE 246
           MDKKEE
Sbjct: 308 MDKKEE 313


>gi|213511012 B-cell receptor-associated protein 31 isoform b [Homo
           sapiens]
          Length = 246

 Score =  471 bits (1213), Expect = e-133
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
           MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV
Sbjct: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60

Query: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
           LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV
Sbjct: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
           TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE
Sbjct: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180

Query: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240
           NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP
Sbjct: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGP 240

Query: 241 MDKKEE 246
           MDKKEE
Sbjct: 241 MDKKEE 246


>gi|56549093 B-cell receptor-associated protein BAP29 isoform a
           [Homo sapiens]
          Length = 348

 Score =  224 bits (572), Expect = 4e-59
 Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)

Query: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
           M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF   +   + ++ N  F+ +I++L+
Sbjct: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60

Query: 61  LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119
           +L +DAVRE+RKY  V T + +  + P A EH  MKLFR+QRNLYI+GFSL    +LRRL
Sbjct: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120

Query: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179
           VTLI+Q A  L++    K QAE+ ++AAKK+MEEN++LK+     G      + E  LE 
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175

Query: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
           EN+ L  D +KLK EL  T   L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230


>gi|56549091 B-cell receptor-associated protein BAP29 isoform b
           [Homo sapiens]
          Length = 241

 Score =  224 bits (572), Expect = 4e-59
 Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)

Query: 1   MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
           M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF   +   + ++ N  F+ +I++L+
Sbjct: 1   MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60

Query: 61  LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119
           +L +DAVRE+RKY  V T + +  + P A EH  MKLFR+QRNLYI+GFSL    +LRRL
Sbjct: 61  VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120

Query: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179
           VTLI+Q A  L++    K QAE+ ++AAKK+MEEN++LK+     G      + E  LE 
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175

Query: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
           EN+ L  D +KLK EL  T   L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 18/127 (14%)

Query: 130  LASNEAFKKQAESASEAAKKYMEE-NDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKAD- 187
            L S EA KK+ E   + A++ MEE  ++++K A     K+      ++LEEEN  L+A+ 
Sbjct: 1650 LRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI------LELEEENDRLRAEV 1703

Query: 188  ----------LQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 237
                      ++ L    AS K++LE+ + +   + K+ + L  E D L EE   L+  +
Sbjct: 1704 HPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQI 1763

Query: 238  DGPMDKK 244
            +G + K+
Sbjct: 1764 EGNVSKQ 1770



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 28/182 (15%)

Query: 79   KVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKK 138
            ++  +N   A+EH      R +    +A F +LL           S+ A +LA N   KK
Sbjct: 2057 EITKENLAQAVEH------RKKAQAELASFKVLLD-------DTQSEAARVLADNLKLKK 2103

Query: 139  QAESASEAAKKYMEENDQ-------------LKKGAAVDGGKLDVGNAE-VKLEEENRSL 184
            + +S  E+ K  M++ D+             LK+   +   KLD    E V LEE    +
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQE-KLDALRREKVHLEETIGEI 2162

Query: 185  KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 244
            +  L K   E+   ++ L+    Q+ A  K    L  + DR+++E  K +      +  K
Sbjct: 2163 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSK 2222

Query: 245  EE 246
            EE
Sbjct: 2223 EE 2224



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 5/115 (4%)

Query: 112 LSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG 171
           +S  +  L   +SQ+   +   +    + +   E  ++ +EE DQ      V      + 
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQ-----QVTEISFSMT 911

Query: 172 NAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 226
              V+L EE  SL  +++ LK++L    +  E  + QV    + S GL + YD +
Sbjct: 912 EKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEM 966



 Score = 32.3 bits (72), Expect = 0.39
 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 8/118 (6%)

Query: 137  KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDEL 195
            K  A+   E  K+  +E  QL+K       K+      VK LE      + DL+  K+ L
Sbjct: 2004 KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENL 2063

Query: 196  ASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL-------QAAVDGPMDKKEE 246
            A   +  +KA+ ++ + +   +    E  R+L ++ KL       + +V   M +K+E
Sbjct: 2064 AQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE 2121



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 15/103 (14%)

Query: 145  EAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLE 203
            EAAKK  E  D+LKK              E+K L  +   ++ + +  ++ +A   + L 
Sbjct: 2668 EAAKKVGEIEDKLKK--------------ELKHLHHDAGIMRNETETAEERVAELARDLV 2713

Query: 204  KAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
            + E ++L + K+++GLT +        + LQ + D   ++ +E
Sbjct: 2714 EMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 17/60 (28%), Positives = 29/60 (48%)

Query: 179  EENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
            +EN+SL+ +L   +  +    + L   E+QV A  K+ + +      L EE  KL   +D
Sbjct: 1497 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD 1556



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 3/53 (5%)

Query: 177  LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
            LE+E   L+   +KL++ L S K  L+KA+ +   +R++ +    +Y+RL E+
Sbjct: 1169 LEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1218



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)

Query: 134 EAFKKQAESASEAAKKYMEENDQL----KKGAAVDGGKLDVGNAEVKLEEENRSLKADLQ 189
           E FKK A++ S A     EE DQL    K+ + V   +  V   E+ L E  R  + D +
Sbjct: 726 EEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYE 785


>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 394

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 7/131 (5%)

Query: 118 RLVTLISQQATLLASNEAFKKQAESASEAAK--KYMEENDQLKKGAAVDGGKLDVGNAEV 175
           RL  L+ ++  LL   +  K Q E   +  K      E+D L+ G       + V + + 
Sbjct: 243 RLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGT-----DMHVMDLQR 297

Query: 176 KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 235
               +   LK  L K + E+ + +Q + + E+QV   +  +E   K  D L  E  KLQ 
Sbjct: 298 DANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQR 357

Query: 236 AVDGPMDKKEE 246
            +   +DK EE
Sbjct: 358 ELRSALDKTEE 368



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 33/158 (20%), Positives = 62/158 (39%), Gaps = 40/158 (25%)

Query: 126 QATLLASNEAFKKQAESASEAAKKYMEENDQLKKG------AAVDGGKLDVGNAEVKLEE 179
           +A  +   E  ++Q E      K + E+  +   G      A++ G     G+ +  +  
Sbjct: 36  EAREIRMKELERQQKEVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI 95

Query: 180 ENRSLKADLQKLKDELASTKQKLEKA----------------------------ENQVLA 211
           +    +A ++++KD LA  ++K +KA                            E Q+  
Sbjct: 96  DT---EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAE 152

Query: 212 MRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDKKEE 246
            R+Q E   KE++R    H+ LQ   A V   + ++EE
Sbjct: 153 SRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 190


>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 640

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 7/131 (5%)

Query: 118 RLVTLISQQATLLASNEAFKKQAESASEAAK--KYMEENDQLKKGAAVDGGKLDVGNAEV 175
           RL  L+ ++  LL   +  K Q E   +  K      E+D L+ G       + V + + 
Sbjct: 489 RLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGT-----DMHVMDLQR 543

Query: 176 KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 235
               +   LK  L K + E+ + +Q + + E+QV   +  +E   K  D L  E  KLQ 
Sbjct: 544 DANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQR 603

Query: 236 AVDGPMDKKEE 246
            +   +DK EE
Sbjct: 604 ELRSALDKTEE 614



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 15/104 (14%)

Query: 149 KYMEENDQLKKGAAVDGGKLD---VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKA 205
           KYM+   ++K   A    K     V NA++  E+ N   + D         + K  L + 
Sbjct: 280 KYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD---------TLKDMLLEL 330

Query: 206 ENQVLAMRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDKKEE 246
           E Q+   R+Q E   KE++R    H+ LQ   A V   + ++EE
Sbjct: 331 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREE 374


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 18/124 (14%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL--------K 185
            EA +K+    +E  K+   END LK        K++    E+++ EEN+ L        K
Sbjct: 2129 EADEKKQLHIAEKLKERERENDSLKD-------KVENLERELQMSEENQELVILDAENSK 2181

Query: 186  ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTK---EYDRLLEEHAKLQAAVDGPMD 242
            A+++ LK ++    + L+  E  ++ +R + E LTK   E    L E  KL ++    ++
Sbjct: 2182 AEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLE 2241

Query: 243  KKEE 246
            +KE+
Sbjct: 2242 EKEQ 2245



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 17/123 (13%)

Query: 130  LASNEAFKKQAESASEAAKKYMEENDQLK-----KGAAVDGGKLDVGNAEVKLEEENRSL 184
            L  +EA KK      +  K+Y  E    +     K   +   KL++   +   EE N SL
Sbjct: 2701 LRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSL 2760

Query: 185  KADLQKLKDELASTK-----------QKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 233
            KA  Q L +EL  TK           ++ E+A+ ++  + K  + L +E + L +E ++L
Sbjct: 2761 KATTQIL-EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2819

Query: 234  QAA 236
            QAA
Sbjct: 2820 QAA 2822



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 137 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 196
           K+Q +   ++ +  +++  Q  +    +G  L   N   +L E   SL+   QK+  EL 
Sbjct: 34  KQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQ--RLMEICESLEKTKQKISHELQ 91

Query: 197 STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 236
             + ++   E Q+ + +KQ E L +E  R   E  + Q A
Sbjct: 92  VKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 21/120 (17%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGG-------KLDVGNAEVKLEEENRSLKA 186
            +  +K+ E  S    +  ++   + K + V+G         L++ N  V+LE++ + L++
Sbjct: 2515 QKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS 2574

Query: 187  DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
                L+D L   +   +  EN++   +       ++ +++  +  +LQ  +     K  E
Sbjct: 2575 KNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE 2634



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 18/142 (12%)

Query: 119 LVTLISQQATLLASNEA----------FKKQAESASEAAKKYMEENDQLKKGAAVDGGKL 168
           LVT    Q +LLA ++             +Q    SE ++  +E  DQ  K +A+   ++
Sbjct: 774 LVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA-DQSPKNSAILQNRV 832

Query: 169 DVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 228
           D  + E  LE + + + +DLQK  +EL   K ++E+   +   M +     T +    L+
Sbjct: 833 D--SLEFSLESQ-KQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQ 889

Query: 229 E----HAKLQAAVDGPMDKKEE 246
           E    H  + A     ++ KE+
Sbjct: 890 EDTSAHQNVVAETLSALENKEK 911



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 29/134 (21%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 174
            L   L  + S++  L    +   K+  +  + ++K  E+  +L+   +     + V  AE
Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAE 2008

Query: 175  VK----------------------LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAM 212
            VK                      L+E+ +SL+ D Q     L+ TK +L   ENQ+  +
Sbjct: 2009 VKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQ----ALSLTKCEL---ENQIAQL 2061

Query: 213  RKQSEGLTKEYDRL 226
             K+ E L KE + L
Sbjct: 2062 NKEKELLVKESESL 2075


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 31/120 (25%), Positives = 64/120 (53%), Gaps = 5/120 (4%)

Query: 128 TLLASNEAFKKQAESASEAAKKYMEENDQLKKGAA-VDGGKLDVGNAEVKLEEENRSLKA 186
           TLL   E  ++ AE      K  + + D  ++ A  +   K++   A   LE +   +KA
Sbjct: 623 TLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVETEEATACLELKFNQIKA 682

Query: 187 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
           +L K K EL  TK++L+K EN+  ++ ++ E   K   +++ ++ +++  ++  +D+KE+
Sbjct: 683 ELAKTKGELIKTKEELKKRENESDSLIQELETSNK---KIITQNQRIKELIN-IIDQKED 738



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 24/106 (22%), Positives = 53/106 (50%), Gaps = 15/106 (14%)

Query: 123  ISQQATLLASN-EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEEN 181
            + ++ T L +N +  K   +   E  +   +E ++LK+  +    +              
Sbjct: 1185 LKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSAR-------------T 1231

Query: 182  RSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLL 227
            ++LKADLQ+ +++ A  K+KL  A+ Q+  ++K+   + ++ D+LL
Sbjct: 1232 QNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKE-VSVMRDEDKLL 1276



 Score = 32.0 bits (71), Expect = 0.51
 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 7/73 (9%)

Query: 169  DVGNAEVKLEEENRSLKADLQKLK-------DELASTKQKLEKAENQVLAMRKQSEGLTK 221
            D+   E+KL+EE   L  +LQ +K       +E  + +Q+ EK + ++ A   +++ L  
Sbjct: 1177 DLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKA 1236

Query: 222  EYDRLLEEHAKLQ 234
            +  R  E++A L+
Sbjct: 1237 DLQRKEEDYADLK 1249


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 13/127 (10%)

Query: 115 LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 174
           LL  +V L    A      +  ++  E A  A  ++ +E  Q +  A+ +  K +     
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKE----- 219

Query: 175 VKLEEENRSLKADLQKLKDELAS-------TKQKLEKAENQVLAMRKQSEGLTKEYDRLL 227
            KLE+E + ++AD+   + E+ +       +K++L+K E Q+   +  +E   KE ++  
Sbjct: 220 -KLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQ 278

Query: 228 EEHAKLQ 234
             +AKLQ
Sbjct: 279 MRNAKLQ 285



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 25/90 (27%), Positives = 51/90 (56%), Gaps = 8/90 (8%)

Query: 148 KKYMEENDQLKKG-AAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTK---QKLE 203
           K  + + D+LK+  +A +   + +   + ++E+E  +LKA+LQKL+ +   TK   +K E
Sbjct: 520 KIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE 579

Query: 204 KAENQVLAMRKQSEG----LTKEYDRLLEE 229
             E ++L +  +++G      KE D+++ E
Sbjct: 580 AEERKLLRIIAEADGERLRQKKELDQVISE 609



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 1/103 (0%)

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
           TL +Q   L    EA KKQAE   +A  + + E D L K               VKL E+
Sbjct: 353 TLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQ 412

Query: 181 -NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKE 222
             R+L+ ++Q  KDE    ++ +   E +      Q+  LT++
Sbjct: 413 AKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQK 455



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 36/151 (23%)

Query: 132 SNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEV----KLEEENR----S 183
           S E F+ + E      KK  +   +L         ++ V +A+V    KL ++++    S
Sbjct: 35  SLEKFRIEYERLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIAS 94

Query: 184 LKADLQKLKDELASTKQKLEKAENQVLAMRKQ---------------------------- 215
           LK +++K    + S   K +KA+  +LA++++                            
Sbjct: 95  LKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRF 154

Query: 216 SEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
            E +TKE D+LL E  KL+ ++    ++++E
Sbjct: 155 KEEVTKERDQLLSEVVKLRESLAQTTEQQQE 185



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 7/112 (6%)

Query: 121 TLISQQATLLASNEA------FKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 174
           T   QQ T  +  EA      F+++ +     A +   + ++L+K        +D    E
Sbjct: 179 TTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTE 238

Query: 175 VK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDR 225
           +K L++  +  K +LQKL+ +L   K   E+A  ++   + ++  L +E ++
Sbjct: 239 IKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQ 290



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 25/136 (18%)

Query: 116 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEV 175
           L++L   + +Q  L   NE   K+ E       K  +EN+Q          +      E+
Sbjct: 253 LQKLEQQLKEQKIL---NERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALEL 309

Query: 176 KL-EEENRSLKADLQKL--------------KDELASTKQKLEKAENQVL-------AMR 213
           K  EEE   ++ D+ KL              +D+ A  +Q  E  +NQ++       A +
Sbjct: 310 KAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASK 369

Query: 214 KQSEGLTKEYDRLLEE 229
           KQ+E   K  D LL E
Sbjct: 370 KQAELDRKAMDELLRE 385


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 8/136 (5%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVG 171
            L  +LVTL+ ++  L    +A  +    A E   + ++   QL+   K         +  
Sbjct: 874  LEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEI 933

Query: 172  NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 226
            NAE+     KLE+E   LK D+  L+  LA  +++    EN+V  + ++  GL +   +L
Sbjct: 934  NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 993

Query: 227  LEEHAKLQAAVDGPMD 242
              E   LQ A    +D
Sbjct: 994  TREKKALQEAHQQALD 1009



 Score = 34.7 bits (78), Expect = 0.078
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 8/113 (7%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            E  KK  E   +  +  ++E +QL    A+ GGK  +     KLE   R L+ +L+  + 
Sbjct: 1781 ERMKKNLEQTVKDLQHRLDEAEQL----ALKGGKKQIQ----KLETRIRELEFELEGEQK 1832

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
            +   + + L K E +V  +  QSE   K   RL +   KLQ  V     + EE
Sbjct: 1833 KNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1885



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 14/83 (16%)

Query: 178 EEENRSLKADLQKLKDELASTKQKLEKAENQV-----------LAMRKQSEGL---TKEY 223
           E+E  ++K + QK KDELA ++ K ++ E ++           L ++ +SE L    +  
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906

Query: 224 DRLLEEHAKLQAAVDGPMDKKEE 246
           D+L++   +L+A +    ++ E+
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAED 929


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           QQA L    +  +K+A+ A EA ++YMEE        A++   LD   AE + E   + +
Sbjct: 134 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 191

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 237
           +A L++  DEL +T  ++ KAE +     K S+G    Y   +L E++A+L+ A+
Sbjct: 192 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 240



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 134 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 192
           E+ +++ E+  E   +   + + LK      G      + ++K LEE+N  LK  L +++
Sbjct: 185 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 244

Query: 193 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           D  +S KQ+  K +  +    ++ E + ++ +RL EE ++ ++ +D
Sbjct: 245 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 290


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           QQA L    +  +K+A+ A EA ++YMEE        A++   LD   AE + E   + +
Sbjct: 248 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 305

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 237
           +A L++  DEL +T  ++ KAE +     K S+G    Y   +L E++A+L+ A+
Sbjct: 306 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 354



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 134 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 192
           E+ +++ E+  E   +   + + LK      G      + ++K LEE+N  LK  L +++
Sbjct: 299 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 358

Query: 193 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           D  +S KQ+  K +  +    ++ E + ++ +RL EE ++ ++ +D
Sbjct: 359 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 404


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           QQA L    +  +K+A+ A EA ++YMEE        A++   LD   AE + E   + +
Sbjct: 134 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 191

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 237
           +A L++  DEL +T  ++ KAE +     K S+G    Y   +L E++A+L+ A+
Sbjct: 192 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 240



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 134 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 192
           E+ +++ E+  E   +   + + LK      G      + ++K LEE+N  LK  L +++
Sbjct: 185 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 244

Query: 193 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           D  +S KQ+  K +  +    ++ E + ++ +RL EE ++ ++ +D
Sbjct: 245 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 290


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 10/115 (8%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           QQA L    +  +K+A+ A EA ++YMEE        A++   LD   AE + E   + +
Sbjct: 268 QQADLQRRLKEARKEAKEALEAKERYMEE--MADTADAIEMATLDKEMAEERAESLQQEV 325

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYD--RLLEEHAKLQAAV 237
           +A L++  DEL +T  ++ KAE +     K S+G    Y   +L E++A+L+ A+
Sbjct: 326 EA-LKERVDEL-TTDLEILKAEIE----EKGSDGAASSYQLKQLEEQNARLKDAL 374



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 134 EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLK 192
           E+ +++ E+  E   +   + + LK      G      + ++K LEE+N  LK  L +++
Sbjct: 319 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 378

Query: 193 DELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           D  +S KQ+  K +  +    ++ E + ++ +RL EE ++ ++ +D
Sbjct: 379 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTID 424


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 24/122 (19%), Positives = 63/122 (51%), Gaps = 2/122 (1%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           Q+  +   +E  +++ E   E  K + +E +++++       +    + E K+ EE R  
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTWDQEEKMREEERMR 563

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 244
           + + +K+++E    +++ EK + Q   MR+Q E + ++ +++ E+  K+    +   +++
Sbjct: 564 ERE-KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622

Query: 245 EE 246
           EE
Sbjct: 623 EE 624



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 37/169 (21%), Positives = 79/169 (46%), Gaps = 10/169 (5%)

Query: 77  TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAF 136
           +EK  +Q N   ++    KL RA+  L     + L   + R+   L  Q+  +    E  
Sbjct: 201 SEKSEIQLN---VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257

Query: 137 KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 196
            +Q E   E   K  E+ +++++       +  +   E +L E+ + L+ + +KL+++  
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQ------EKRLREQEKELREQEKELR-EQKKLREQEE 310

Query: 197 STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKE 245
             +++ EK   Q   MR+Q E + ++ +RL E+  +++       D++E
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 23/122 (18%), Positives = 58/122 (47%), Gaps = 4/122 (3%)

Query: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSL 184
           Q+  +    E  ++Q E   E  +K  E+ +++ +       K+     E K++E+   +
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE----KMWEQEEEDKMQEQEEMM 634

Query: 185 KADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKK 244
               +K++++     ++ EK   Q   MR+Q E +  + +++ E+  K+Q   +   +++
Sbjct: 635 WEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694

Query: 245 EE 246
           E+
Sbjct: 695 EK 696



 Score = 32.3 bits (72), Expect = 0.39
 Identities = 33/186 (17%), Positives = 79/186 (42%), Gaps = 26/186 (13%)

Query: 68  REIRKYDDVT--EKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQ 125
           ++IRK ++    ++  L+   G M     K+ R ++ L             R     + +
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL-------------REQEKELRE 294

Query: 126 QATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 185
           Q   L   +  ++Q E   E  +K  E+ +++++          +   E +L E+ + ++
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE------KMWRQEERLWEQEKQMR 348

Query: 186 ADLQKLKDELASTKQKLEKAENQVLAMRKQ-----SEGLTKEYDRLLEEHAKLQAAVDGP 240
              QK++D+     ++ E+   +   MR+Q      E   +E +R+ E   K++   +  
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408

Query: 241 MDKKEE 246
            +++E+
Sbjct: 409 REQEEK 414


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 14/98 (14%)

Query: 144  SEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLE 203
            ++  +++ +E + LK+ AA    +L        L+EEN  L  +L + +DE+ S  QKLE
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSA------LQEENVKLAEELGRSRDEVTS-HQKLE 1154

Query: 204  K----AENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 237
            +      NQ+L M+K+     K+ D   EE A LQ ++
Sbjct: 1155 EERSVLNNQLLEMKKRESKFIKDAD---EEKASLQKSI 1189



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 4/102 (3%)

Query: 138  KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGN---AEVKLEEENRSLKADLQKLKDE 194
            K  +S  EAAKK+ EE  +L++  +    K++  +    E+K   E R+      K ++ 
Sbjct: 939  KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSETKTKHEEI 997

Query: 195  LASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 236
            L + ++ L   E+++   R+++ GL +E + L ++  K +AA
Sbjct: 998  LQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA 1039



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 10/119 (8%)

Query: 125  QQATLLASNEAFKKQAESASEA--AKKYMEENDQLKKGAAVDGGKL-DVGNAEVKLEEEN 181
            + + LL   E  +KQA+ A  A  A+  M+  +Q+ K        L D      KL+ E 
Sbjct: 1018 ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1077

Query: 182  RSLKA-------DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 233
             +LK        +L K K+ L    QK+E+   ++  +++ +   +++   L EE+ KL
Sbjct: 1078 DTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1136



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 5/168 (2%)

Query: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
           LL +DA+R+    +  +E   L+    A E   +K    ++N   +  S +   L  R +
Sbjct: 727 LLDLDALRKASS-EGKSEMKKLRQQLEAAEK-QIKHLEIEKNAESSKASSITRELQGREL 784

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
            L + Q  L   ++  +   +      +K+ E +++     +V     +  N   + EE+
Sbjct: 785 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEE---AVSVQRSMQETVNKLHQKEEQ 841

Query: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 228
              L +DL+KL++ LA  + K  + + +   + K  E L  +   +++
Sbjct: 842 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 889



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 24/191 (12%)

Query: 69  EIRKYDDVTEKVNLQNNPGAMEHFHMK----LFRAQRNLYIAGFSL-------------L 111
           E+ + D   E  +L+ + GA E  H K    L+ A   L     SL             +
Sbjct: 514 EVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDV 573

Query: 112 LSFLLRRLVTLI-SQQATLLASNEAFKKQ--AESASEAAKKYMEENDQLKKGAAVDGGKL 168
           ++    +L T I S Q  +     +F K    E+A  A  K   E  +L     ++  + 
Sbjct: 574 IALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQN 633

Query: 169 DVGNAEVKLEEENRSLKADLQKL----KDELASTKQKLEKAENQVLAMRKQSEGLTKEYD 224
              +      +E  +L+A L K+    ++ L + + KL+KAE+Q L   + +    +E +
Sbjct: 634 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 693

Query: 225 RLLEEHAKLQA 235
             ++E   LQA
Sbjct: 694 IKVKELEVLQA 704


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 14/98 (14%)

Query: 144  SEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLE 203
            ++  +++ +E + LK+ AA    +L        L+EEN  L  +L + +DE+ S  QKLE
Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSA------LQEENVKLAEELGRSRDEVTS-HQKLE 1189

Query: 204  K----AENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 237
            +      NQ+L M+K+     K+ D   EE A LQ ++
Sbjct: 1190 EERSVLNNQLLEMKKRESKFIKDAD---EEKASLQKSI 1224



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 4/102 (3%)

Query: 138  KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGN---AEVKLEEENRSLKADLQKLKDE 194
            K  +S  EAAKK+ EE  +L++  +    K++  +    E+K   E R+      K ++ 
Sbjct: 974  KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYE-RATSETKTKHEEI 1032

Query: 195  LASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 236
            L + ++ L   E+++   R+++ GL +E + L ++  K +AA
Sbjct: 1033 LQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAA 1074



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 10/119 (8%)

Query: 125  QQATLLASNEAFKKQAESASEA--AKKYMEENDQLKKGAAVDGGKL-DVGNAEVKLEEEN 181
            + + LL   E  +KQA+ A  A  A+  M+  +Q+ K        L D      KL+ E 
Sbjct: 1053 ENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1112

Query: 182  RSLKA-------DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 233
             +LK        +L K K+ L    QK+E+   ++  +++ +   +++   L EE+ KL
Sbjct: 1113 DTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1171



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 5/168 (2%)

Query: 61  LLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLV 120
           LL +DA+R+    +  +E   L+    A E   +K    ++N   +  S +   L  R +
Sbjct: 762 LLDLDALRKASS-EGKSEMKKLRQQLEAAEK-QIKHLEIEKNAESSKASSITRELQGREL 819

Query: 121 TLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEE 180
            L + Q  L   ++  +   +      +K+ E +++     +V     +  N   + EE+
Sbjct: 820 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEE---AVSVQRSMQETVNKLHQKEEQ 876

Query: 181 NRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 228
              L +DL+KL++ LA  + K  + + +   + K  E L  +   +++
Sbjct: 877 FNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 924



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 24/191 (12%)

Query: 69  EIRKYDDVTEKVNLQNNPGAMEHFHMK----LFRAQRNLYIAGFSL-------------L 111
           E+ + D   E  +L+ + GA E  H K    L+ A   L     SL             +
Sbjct: 549 EVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDV 608

Query: 112 LSFLLRRLVTLI-SQQATLLASNEAFKKQ--AESASEAAKKYMEENDQLKKGAAVDGGKL 168
           ++    +L T I S Q  +     +F K    E+A  A  K   E  +L     ++  + 
Sbjct: 609 IALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQN 668

Query: 169 DVGNAEVKLEEENRSLKADLQKL----KDELASTKQKLEKAENQVLAMRKQSEGLTKEYD 224
              +      +E  +L+A L K+    ++ L + + KL+KAE+Q L   + +    +E +
Sbjct: 669 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 728

Query: 225 RLLEEHAKLQA 235
             ++E   LQA
Sbjct: 729 IKVKELEVLQA 739


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 22/83 (26%), Positives = 45/83 (54%)

Query: 152  EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLA 211
            E+N   ++        L V +  +++E  N +L+A+ Q LK +L   + +    + Q+LA
Sbjct: 1026 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1085

Query: 212  MRKQSEGLTKEYDRLLEEHAKLQ 234
            +++Q+  L ++   L  ++AKLQ
Sbjct: 1086 LQRQTVSLQEQNTTLQTQNAKLQ 1108



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)

Query: 118  RLVTLISQQATLLASNEAFK---KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 174
            RL+ +    ATL A  +A K   KQ E+ +   +  +    +           L   NA 
Sbjct: 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA- 1105

Query: 175  VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
             KL+ EN +L +    L ++ A    +    EN+  ++ K+ E L   YD L+++H KL+
Sbjct: 1106 -KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1164



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 26/141 (18%)

Query: 116 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYME---------------------EN 154
           LRR V  +   +  +A  +   K+ ES  E  KK +E                     EN
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765

Query: 155 DQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMR 213
            +L+K       K+    +E++ LE EN++L+ +L++LK     + ++LE+ E +  ++ 
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK----ISSKRLEQLEKENKSLE 821

Query: 214 KQSEGLTKEYDRLLEEHAKLQ 234
           +++  L K+  +L +E+ +L+
Sbjct: 822 QETSQLEKDKKQLEKENKRLR 842



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 171 GNAE--VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 228
           GNA   +K+E+EN+ L   ++ L++E+   KQ L+  +N    + K+   L K  + L E
Sbjct: 488 GNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE 547



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 11/130 (8%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLD----- 169
            L+ +   L+ QQ++L   NE+  K+ E         ++++++L+        + +     
Sbjct: 1121 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 1180

Query: 170  ---VGNAEVKLEEENRSLK---ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEY 223
               + +A   LE E+R L+     L K K +L   ++ L+  + ++L   K  E +  EY
Sbjct: 1181 HGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1240

Query: 224  DRLLEEHAKL 233
             +L  E+ +L
Sbjct: 1241 KKLCGENDRL 1250



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 4/55 (7%)

Query: 175 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           +KLE EN+S    L K  +EL +T   +E   +++L M K+++ L+K+ + L  E
Sbjct: 463 LKLEMENQS----LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 17/108 (15%)

Query: 134 EAFKKQAESASEAAKKYM---EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK 190
           E +K++ E A E   +     +EN+ L+K   +   K+     E  LE+EN  L+ + +K
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQK--KITNLKITCEKIEA-LEQENSELERENRK 674

Query: 191 LKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           LK  L S K            +  Q E L KE  +L EE+ +L+  V+
Sbjct: 675 LKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVE 711



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 12/105 (11%)

Query: 118 RLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVGNAE 174
           +L + +S+    L   E +K + E   E  +  +E    L+   +G      KL      
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLH----- 378

Query: 175 VKLEEENRSLKADLQKLKDELASTKQKLEK--AENQVLAM-RKQS 216
            +LE+EN  LKA L  ++ E    ++K+E+   EN  L M +KQS
Sbjct: 379 -ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
            sapiens]
          Length = 1870

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 22/83 (26%), Positives = 45/83 (54%)

Query: 152  EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLA 211
            E+N   ++        L V +  +++E  N +L+A+ Q LK +L   + +    + Q+LA
Sbjct: 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1084

Query: 212  MRKQSEGLTKEYDRLLEEHAKLQ 234
            +++Q+  L ++   L  ++AKLQ
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQ 1107



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)

Query: 118  RLVTLISQQATLLASNEAFK---KQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAE 174
            RL+ +    ATL A  +A K   KQ E+ +   +  +    +           L   NA 
Sbjct: 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA- 1104

Query: 175  VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
             KL+ EN +L +    L ++ A    +    EN+  ++ K+ E L   YD L+++H KL+
Sbjct: 1105 -KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLE 1163



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 26/141 (18%)

Query: 116 LRRLVTLISQQATLLASNEAFKKQAESASEAAKKYME---------------------EN 154
           LRR V  +   +  +A  +   K+ ES  E  KK +E                     EN
Sbjct: 706 LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN 765

Query: 155 DQLKKGAAVDGGKLDVGNAEVK-LEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMR 213
            +L+K       K+    +E++ LE EN++L+ +L++LK     + ++LE+ E +  ++ 
Sbjct: 766 QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK----ISSKRLEQLEKENKSLE 821

Query: 214 KQSEGLTKEYDRLLEEHAKLQ 234
           +++  L K+  +L +E+ +L+
Sbjct: 822 QETSQLEKDKKQLEKENKRLR 842



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 171 GNAE--VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE 228
           GNA   +K+E+EN+ L   ++ L++E+   KQ L+  +N    + K+   L K  + L E
Sbjct: 488 GNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE 547



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 11/130 (8%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLD----- 169
            L+ +   L+ QQ++L   NE+  K+ E         ++++++L+        + +     
Sbjct: 1120 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 1179

Query: 170  ---VGNAEVKLEEENRSLK---ADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEY 223
               + +A   LE E+R L+     L K K +L   ++ L+  + ++L   K  E +  EY
Sbjct: 1180 HGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1239

Query: 224  DRLLEEHAKL 233
             +L  E+ +L
Sbjct: 1240 KKLCGENDRL 1249



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 4/55 (7%)

Query: 175 VKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           +KLE EN+S    L K  +EL +T   +E   +++L M K+++ L+K+ + L  E
Sbjct: 463 LKLEMENQS----LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENE 513



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 17/108 (15%)

Query: 134 EAFKKQAESASEAAKKYM---EENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK 190
           E +K++ E A E   +     +EN+ L+K   +   K+     E  LE+EN  L+ + +K
Sbjct: 618 EHYKEKGERAEELENELHHLEKENELLQK--KITNLKITCEKIEA-LEQENSELERENRK 674

Query: 191 LKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVD 238
           LK  L S K            +  Q E L KE  +L EE+ +L+  V+
Sbjct: 675 LKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVE 711



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 12/105 (11%)

Query: 118 RLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLK---KGAAVDGGKLDVGNAE 174
           +L + +S+    L   E +K + E   E  +  +E    L+   +G      KL      
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLH----- 378

Query: 175 VKLEEENRSLKADLQKLKDELASTKQKLEK--AENQVLAM-RKQS 216
            +LE+EN  LKA L  ++ E    ++K+E+   EN  L M +KQS
Sbjct: 379 -ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)

Query: 111  LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 170
            LL   L+    L ++   +     A K++ E      +  +EE +   +G  +   +  +
Sbjct: 891  LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 948

Query: 171  GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
                + LEE+    +A  QKL+ E  + + K++K E+++L M  Q+  L+KE  +LLEE
Sbjct: 949  AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1006



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 187 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           ++Q  +DEL  TK++ +KAEN++  + ++   LT+E + L E+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 132  SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 190
            S EA   Q +    AA++  ++ D  K+  A +    L   NA   L++E R L+A + +
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1740

Query: 191  LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 222
            L++EL   +  +E   ++V    +Q+E L+ E
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)

Query: 133  NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 190
            NEA  K  + A + A    +  D  +        KL+V     +LEEE  SL+  L +  
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356

Query: 191  ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 231
                        L  +L+ +K+KL+   + V A+       +K+ E LT++Y+     + 
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416

Query: 232  KLQ 234
            KL+
Sbjct: 1417 KLE 1419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 99   AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 156
            A++NL  +I+  ++ LS   ++L    S    L    + F+K+ E+ ++  ++     D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417

Query: 157  LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 215
            L+K              + +L++E   L  DL   + +L S  +K ++  +Q+LA  K  
Sbjct: 1418 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1463

Query: 216  SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 246
            S     E DR   E  +       L  A++  ++ KEE
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)

Query: 147  AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 197
            AK  +++N Q L+K  A   G+L V G A+ ++E + + L+A +Q+L+ +        A 
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277

Query: 198  TKQKLEKAENQV---LAMRKQSEG 218
               K+ K +N+V     M  ++EG
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEG 1301


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)

Query: 111  LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 170
            LL   L+    L ++   +     A K++ E      +  +EE +   +G  +   +  +
Sbjct: 898  LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 955

Query: 171  GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
                + LEE+    +A  QKL+ E  + + K++K E+++L M  Q+  L+KE  +LLEE
Sbjct: 956  AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1013



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 187 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           ++Q  +DEL  TK++ +KAEN++  + ++   LT+E + L E+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 132  SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 190
            S EA   Q +    AA++  ++ D  K+  A +    L   NA   L++E R L+A + +
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1747

Query: 191  LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 222
            L++EL   +  +E   ++V    +Q+E L+ E
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)

Query: 133  NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 190
            NEA  K  + A + A    +  D  +        KL+V     +LEEE  SL+  L +  
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363

Query: 191  ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 231
                        L  +L+ +K+KL+   + V A+       +K+ E LT++Y+     + 
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423

Query: 232  KLQ 234
            KL+
Sbjct: 1424 KLE 1426



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 99   AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 156
            A++NL  +I+  ++ LS   ++L    S    L    + F+K+ E+ ++  ++     D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424

Query: 157  LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 215
            L+K              + +L++E   L  DL   + +L S  +K ++  +Q+LA  K  
Sbjct: 1425 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1470

Query: 216  SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 246
            S     E DR   E  +       L  A++  ++ KEE
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)

Query: 147  AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 197
            AK  +++N Q L+K  A   G+L V G A+ ++E + + L+A +Q+L+ +        A 
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284

Query: 198  TKQKLEKAENQV---LAMRKQSEG 218
               K+ K +N+V     M  ++EG
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEG 1308


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)

Query: 111  LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 170
            LL   L+    L ++   +     A K++ E      +  +EE +   +G  +   +  +
Sbjct: 898  LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 955

Query: 171  GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
                + LEE+    +A  QKL+ E  + + K++K E+++L M  Q+  L+KE  +LLEE
Sbjct: 956  AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1013



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 187 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           ++Q  +DEL  TK++ +KAEN++  + ++   LT+E + L E+
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 132  SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 190
            S EA   Q +    AA++  ++ D  K+  A +    L   NA   L++E R L+A + +
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1747

Query: 191  LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 222
            L++EL   +  +E   ++V    +Q+E L+ E
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)

Query: 133  NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 190
            NEA  K  + A + A    +  D  +        KL+V     +LEEE  SL+  L +  
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363

Query: 191  ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 231
                        L  +L+ +K+KL+   + V A+       +K+ E LT++Y+     + 
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423

Query: 232  KLQ 234
            KL+
Sbjct: 1424 KLE 1426



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 99   AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 156
            A++NL  +I+  ++ LS   ++L    S    L    + F+K+ E+ ++  ++     D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424

Query: 157  LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 215
            L+K              + +L++E   L  DL   + +L S  +K ++  +Q+LA  K  
Sbjct: 1425 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1470

Query: 216  SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 246
            S     E DR   E  +       L  A++  ++ KEE
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1508



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)

Query: 147  AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 197
            AK  +++N Q L+K  A   G+L V G A+ ++E + + L+A +Q+L+ +        A 
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284

Query: 198  TKQKLEKAENQV---LAMRKQSEG 218
               K+ K +N+V     M  ++EG
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEG 1308


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 3/119 (2%)

Query: 111  LLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDV 170
            LL   L+    L ++   +     A K++ E      +  +EE +   +G  +   +  +
Sbjct: 891  LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKM 948

Query: 171  GNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
                + LEE+    +A  QKL+ E  + + K++K E+++L M  Q+  L+KE  +LLEE
Sbjct: 949  AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-RKLLEE 1006



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 187 DLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
           ++Q  +DEL  TK++ +KAEN++  + ++   LT+E + L E+
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 132  SNEAFKKQAESASEAAKKYMEENDQLKKGAAVD-GGKLDVGNAEVKLEEENRSLKADLQK 190
            S EA   Q +    AA++  ++ D  K+  A +    L   NA   L++E R L+A + +
Sbjct: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA---LQDEKRRLEARIAQ 1740

Query: 191  LKDELASTKQKLEKAENQVLAMRKQSEGLTKE 222
            L++EL   +  +E   ++V    +Q+E L+ E
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 21/123 (17%)

Query: 133  NEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQK-- 190
            NEA  K  + A + A    +  D  +        KL+V     +LEEE  SL+  L +  
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356

Query: 191  ------------LKDELASTKQKLEKAENQVLAM-------RKQSEGLTKEYDRLLEEHA 231
                        L  +L+ +K+KL+   + V A+       +K+ E LT++Y+     + 
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416

Query: 232  KLQ 234
            KL+
Sbjct: 1417 KLE 1419



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 99   AQRNL--YIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQ 156
            A++NL  +I+  ++ LS   ++L    S    L    + F+K+ E+ ++  ++     D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417

Query: 157  LKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQ- 215
            L+K              + +L++E   L  DL   + +L S  +K ++  +Q+LA  K  
Sbjct: 1418 LEK-------------TKNRLQQELDDLVVDLDNQR-QLVSNLEKKQRKFDQLLAEEKNI 1463

Query: 216  SEGLTKEYDRLLEEHAK-------LQAAVDGPMDKKEE 246
            S     E DR   E  +       L  A++  ++ KEE
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEE 1501



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 12/84 (14%)

Query: 147  AKKYMEENDQ-LKKGAAVDGGKLDV-GNAEVKLEEENRSLKADLQKLKDEL-------AS 197
            AK  +++N Q L+K  A   G+L V G A+ ++E + + L+A +Q+L+ +        A 
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277

Query: 198  TKQKLEKAENQV---LAMRKQSEG 218
               K+ K +N+V     M  ++EG
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEG 1301


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 8/136 (5%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG--- 171
            L  ++V+L+ ++  L    +A +     A E   + ++   QL+        +L+     
Sbjct: 875  LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 934

Query: 172  NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 226
            NAE+     KLE+E   LK D+  L+  LA  +++    EN+V  + ++  GL +   +L
Sbjct: 935  NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994

Query: 227  LEEHAKLQAAVDGPMD 242
             +E   LQ A    +D
Sbjct: 995  TKEKKALQEAHQQALD 1010



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 134  EAFKKQAESASEAAKKYME--ENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKL 191
            E  K + +SA E A+  +E  E   L+     +  K ++     + +EE    K + Q++
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV 1595

Query: 192  KDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 236
             D L ++     ++ N+VL ++K+ EG   E +  L  HA   AA
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL-SHANRMAA 1639



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 8/113 (7%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            E  KK  E   +  +  ++E +Q+    A+ GGK  +     KLE   R L+ +L+  + 
Sbjct: 1782 ERMKKNMEQTIKDLQHRLDEAEQI----ALKGGKKQLQ----KLEARVRELEGELEAEQK 1833

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
              A + + + K+E ++  +  Q+E   K   RL +   KLQ  V     + EE
Sbjct: 1834 RNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)

Query: 123  ISQQATLLASNEAFKKQAESASEAAKKYME-------------ENDQLKKGAAVDGGKLD 169
            + QQ   L  +   +K+     E AK+ +E             END+L+    +   + D
Sbjct: 1029 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088

Query: 170  VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE- 228
            +     K+E+E + L   LQK   E  +  ++LE+        R + E L  +  R LE 
Sbjct: 1089 INQQNSKIEDE-QVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147

Query: 229  -----EHAKLQAAVDGPMDKKEE 246
                 E A    +V   M+KK E
Sbjct: 1148 ISERLEEAGGATSVQIEMNKKRE 1170


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 122  LISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEEN 181
            L ++Q  L  + E      +S  +   K  E +++L+    V+    D+     KLE+E 
Sbjct: 940  LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNA---DLAARRRKLEDEC 996

Query: 182  RSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAA 236
              LK D+  LK  LA  +++ +  EN+V  + ++   L +   RL +E   LQ A
Sbjct: 997  TELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEA 1051



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 8/113 (7%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            E  KK  E      +  +EE +Q    AA+ GGK  V     KLE + R L+A+L   + 
Sbjct: 1829 ERMKKTLEQTVRELQARLEEAEQ----AALRGGKKQVQ----KLEAKVRELEAELDAEQK 1880

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
            + A   + + K E +V  +  Q+E   K   R+ +   KLQ+ V     + EE
Sbjct: 1881 KHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 35/154 (22%), Positives = 72/154 (46%), Gaps = 27/154 (17%)

Query: 120  VTLISQQATLLASN--------EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG 171
            VTL  ++AT  A+         E   ++     E  ++ +E   +  +G   +  +L  G
Sbjct: 1477 VTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536

Query: 172  NAEV-----KLEEENRSLKADLQKLKD----------ELASTKQKLEKAENQVLAMRKQS 216
            + E       L+ EN++L+ ++  L D          EL  TK+ LE  ++++ A  +++
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596

Query: 217  EGLTKEYD----RLLEEHAKLQAAVDGPMDKKEE 246
            EG  +  +    R+  E ++++A VD  + +K+E
Sbjct: 1597 EGALELEETKTLRIQLELSQVKAEVDRKLAEKDE 1630



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 6/102 (5%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            +A  ++AE A E     +EE   L+    +   K +V     + +EE  +L+ + Q+  +
Sbjct: 1590 QAALEEAEGALE-----LEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVE 1644

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQA 235
             L ++     +A N+ L ++K+ EG   + +  L  HA  QA
Sbjct: 1645 SLQASLDAETRARNEALRLKKKMEGDLNDLELQL-GHATRQA 1685



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 22/100 (22%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            E  +++AE+ +E  +   + N ++ +  +    + D      +LEE  + L   LQ+ ++
Sbjct: 1394 EQHEEEAEAQAELQRLLSKANAEVAQWRSKY--EADAIQRTEELEEAKKKLALRLQEAEE 1451

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKL 233
             + +   K    E   L ++ +SE +T E +R     A L
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAAL 1491



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 7/93 (7%)

Query: 137  KKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELA 196
            K   ES ++AA+   +  ++LKK  +      ++    +++E+E + L A +QK   EL 
Sbjct: 1109 KLTQESVADAAQDKQQLEEKLKKKDS------ELSQLSLRVEDE-QLLGAQMQKKIKELQ 1161

Query: 197  STKQKLEKAENQVLAMRKQSEGLTKEYDRLLEE 229
            +  ++LE+      A R + E    E  R LEE
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEE 1194


>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
          Length = 618

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 14/111 (12%)

Query: 128 TLLASNEAFKKQAES--ASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 185
           +LL + +  KK  ES    E +    +  + L+ G +     + + N    +E E + L+
Sbjct: 48  SLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLR 107

Query: 186 ADLQKL-------KDELASTKQKLEKAENQVLAMRKQSEGL-----TKEYD 224
           A +++L       +DELA+T+QKL+K+E  V  + ++ + L      K+YD
Sbjct: 108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYD 158


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 8/136 (5%)

Query: 115  LLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVG--- 171
            L  ++V+L+ ++  L    +A +     A E   + ++   QL+        +L+     
Sbjct: 873  LEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEM 932

Query: 172  NAEV-----KLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRL 226
            NAE+     KLE+E   LK D+  L+  LA  +++    EN+V  + ++  GL +   +L
Sbjct: 933  NAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 992

Query: 227  LEEHAKLQAAVDGPMD 242
             +E   LQ A    +D
Sbjct: 993  TKEKKALQEAHQQALD 1008



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 8/113 (7%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKD 193
            E  KK  E   +  +  ++E +Q+    A+ GGK  +     KLE   R L+ +L+  + 
Sbjct: 1780 ERMKKNMEQTIKDLQHRLDEAEQI----ALKGGKKQLQ----KLEARVRELENELEAEQK 1831

Query: 194  ELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE 246
              A + + + K+E ++  +  Q+E   K   RL +   KLQ  V     + EE
Sbjct: 1832 RNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 16/122 (13%)

Query: 134  EAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLK- 192
            EA  +   +A+   KK+ +   +L  G  +D    ++   + KLE+E    K +L  +  
Sbjct: 1180 EATLQHEATAAALRKKHADSVAEL--GEQID----NLQRVKQKLEKEKSEFKLELDDVTS 1233

Query: 193  --DELASTKQKLEKA----ENQVLAMRKQSEGLTKEYDRLLEEHAKLQ---AAVDGPMDK 243
              +++   K  LEK     E+Q+   R ++E   +  + L  + AKLQ     +   +D+
Sbjct: 1234 NMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDE 1293

Query: 244  KE 245
            KE
Sbjct: 1294 KE 1295



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 20/143 (13%)

Query: 123  ISQQATLLASNEAFKKQAESASEAAKKYME-------------ENDQLKKGAAVDGGKLD 169
            + QQ   L  +   +K+     E AK+ +E             END+ +    +     +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086

Query: 170  VGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLE- 228
            +     ++E+E ++L + LQK   EL +  ++LE+        R + E L  +  R LE 
Sbjct: 1087 LNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145

Query: 229  -----EHAKLQAAVDGPMDKKEE 246
                 E A    +V   M+KK E
Sbjct: 1146 ISERLEEAGGATSVQIEMNKKRE 1168


>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 14/111 (12%)

Query: 128 TLLASNEAFKKQAES--ASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLK 185
           +LL + +  KK  ES    E +    +  + L+ G +     + + N    +E E + L+
Sbjct: 48  SLLETLKCLKKDDESNLVEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLR 107

Query: 186 ADLQKL-------KDELASTKQKLEKAENQVLAMRKQSEGL-----TKEYD 224
           A +++L       +DELA+T+QKL+K+E  V  + ++ + L      K+YD
Sbjct: 108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYD 158


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,356,055
Number of Sequences: 37866
Number of extensions: 268571
Number of successful extensions: 4564
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 391
Number of HSP's that attempted gapping in prelim test: 2665
Number of HSP's gapped (non-prelim): 2126
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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