Guide to the Human Genome
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Search of human proteins with 21264361

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21264361 mannan-binding lectin serine protease 2 isoform 2
precursor [Homo sapiens]
         (185 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21264361 mannan-binding lectin serine protease 2 isoform 2 pr...   397   e-111
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...   390   e-109
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H...   207   5e-54
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...   207   5e-54
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...   207   5e-54
gi|66347875 complement component 1, r subcomponent [Homo sapiens]     145   3e-35
gi|4502495 complement component 1, s subcomponent precursor [Hom...   140   6e-34
gi|41393602 complement component 1, s subcomponent precursor [Ho...   140   6e-34
gi|6912724 tolloid-like 2 [Homo sapiens]                               98   5e-21
gi|22547221 tolloid-like 1 [Homo sapiens]                              97   1e-20
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...    96   2e-20
gi|7706083 complement component 1, r subcomponent-like precursor...    75   3e-14
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...    74   7e-14
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...    74   7e-14
gi|50659100 regeneration associated muscle protease isoform b [H...    72   2e-13
gi|50659098 regeneration associated muscle protease isoform a [H...    70   8e-13
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]      62   2e-10
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]      62   2e-10
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...    62   2e-10
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...    62   2e-10
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...    62   2e-10
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...    62   4e-10
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom...    62   4e-10
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho...    62   4e-10
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom...    62   4e-10
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]           60   8e-10
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    60   1e-09
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa...    60   1e-09
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    60   1e-09
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            59   2e-09

>gi|21264361 mannan-binding lectin serine protease 2 isoform 2
           precursor [Homo sapiens]
          Length = 185

 Score =  397 bits (1020), Expect = e-111
 Identities = 185/185 (100%), Positives = 185/185 (100%)

Query: 1   MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY 60
           MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY
Sbjct: 1   MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY 60

Query: 61  FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD 120
           FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD
Sbjct: 61  FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD 120

Query: 121 YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
           YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC
Sbjct: 121 YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180

Query: 181 SEQSL 185
           SEQSL
Sbjct: 181 SEQSL 185


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score =  390 bits (1002), Expect = e-109
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY 60
           MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY
Sbjct: 1   MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY 60

Query: 61  FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD 120
           FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD
Sbjct: 61  FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSD 120

Query: 121 YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
           YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC
Sbjct: 121 YSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180

Query: 181 S 181
           S
Sbjct: 181 S 181



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 13/112 (11%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTH-FDLEL--SHLCEYDFVKLSSGAK 84
           G L+SP +P  Y       ++++   G+ + L F   FD+E     LC YDF+K+ +  +
Sbjct: 194 GELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDRE 253

Query: 85  VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
                CG+  T   R   K       +++ ITF +D S +   TG++  Y +
Sbjct: 254 EHGPFCGK--TLPHRIETK------SNTVTITFVTDESGD--HTGWKIHYTS 295


>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
           sapiens]
          Length = 380

 Score =  207 bits (526), Expect = 5e-54
 Identities = 93/181 (51%), Positives = 128/181 (70%), Gaps = 1/181 (0%)

Query: 1   MRLLTLLGLLCGSVATPLGPKWP-EPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRL 59
           MR L L   LC S++           +FG++ SPG+P  Y +D E  W +T P G+R++L
Sbjct: 1   MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL 60

Query: 60  YFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRS 119
           YF HF+LE S+LCEYD+VK+ +  +VLAT CG+E+TDTE+ PG++   S GS + ITFRS
Sbjct: 61  YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS 120

Query: 120 DYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRT 179
           D+SNE+ FTGF+A Y A D+DEC+    E  +CDH+CHN++GG+YCSCR GY+LH + RT
Sbjct: 121 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT 180

Query: 180 C 180
           C
Sbjct: 181 C 181



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTH-FDLELSHL---CEYDFVKLSSGA 83
           G + SP FP  Y    E  +T+    G+ + L F   FD+E  H    C YD++K+  G 
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE-DHPEVPCPYDYIKIKVGP 253

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           KVL   CG      E+AP  +   +   S+ I F SD S E    G+   Y A   +EC
Sbjct: 254 KVLGPFCG------EKAP--EPISTQSHSVLILFHSDNSGEN--RGWRLSYRAAG-NEC 301


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score =  207 bits (526), Expect = 5e-54
 Identities = 93/181 (51%), Positives = 128/181 (70%), Gaps = 1/181 (0%)

Query: 1   MRLLTLLGLLCGSVATPLGPKWP-EPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRL 59
           MR L L   LC S++           +FG++ SPG+P  Y +D E  W +T P G+R++L
Sbjct: 1   MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL 60

Query: 60  YFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRS 119
           YF HF+LE S+LCEYD+VK+ +  +VLAT CG+E+TDTE+ PG++   S GS + ITFRS
Sbjct: 61  YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS 120

Query: 120 DYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRT 179
           D+SNE+ FTGF+A Y A D+DEC+    E  +CDH+CHN++GG+YCSCR GY+LH + RT
Sbjct: 121 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT 180

Query: 180 C 180
           C
Sbjct: 181 C 181



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTH-FDLELSHL---CEYDFVKLSSGA 83
           G + SP FP  Y    E  +T+    G+ + L F   FD+E  H    C YD++K+  G 
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE-DHPEVPCPYDYIKIKVGP 253

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           KVL   CG      E+AP  +   +   S+ I F SD S E    G+   Y A   +EC
Sbjct: 254 KVLGPFCG------EKAP--EPISTQSHSVLILFHSDNSGEN--RGWRLSYRAAG-NEC 301


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score =  207 bits (526), Expect = 5e-54
 Identities = 93/181 (51%), Positives = 128/181 (70%), Gaps = 1/181 (0%)

Query: 1   MRLLTLLGLLCGSVATPLGPKWP-EPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRL 59
           MR L L   LC S++           +FG++ SPG+P  Y +D E  W +T P G+R++L
Sbjct: 1   MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL 60

Query: 60  YFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRS 119
           YF HF+LE S+LCEYD+VK+ +  +VLAT CG+E+TDTE+ PG++   S GS + ITFRS
Sbjct: 61  YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS 120

Query: 120 DYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRT 179
           D+SNE+ FTGF+A Y A D+DEC+    E  +CDH+CHN++GG+YCSCR GY+LH + RT
Sbjct: 121 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT 180

Query: 180 C 180
           C
Sbjct: 181 C 181



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTH-FDLELSHL---CEYDFVKLSSGA 83
           G + SP FP  Y    E  +T+    G+ + L F   FD+E  H    C YD++K+  G 
Sbjct: 195 GVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE-DHPEVPCPYDYIKIKVGP 253

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           KVL   CG      E+AP  +   +   S+ I F SD S E    G+   Y A   +EC
Sbjct: 254 KVLGPFCG------EKAP--EPISTQSHSVLILFHSDNSGEN--RGWRLSYRAAG-NEC 301


>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
          Length = 705

 Score =  145 bits (365), Expect = 3e-35
 Identities = 72/171 (42%), Positives = 101/171 (59%), Gaps = 10/171 (5%)

Query: 23  PEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG 82
           P+ +FG + SP FP  Y N+ E    +T P GYR++L F  FDLE S  C YD+VK+S+ 
Sbjct: 22  PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISAD 81

Query: 83  AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP-----FTGFEAFYAAE 137
            K L   CGQ  +     PGK  F S G+ + +TF +D+SNE+      + GF A+Y A 
Sbjct: 82  KKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAV 141

Query: 138 DIDEC--QVAPGE---APTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSEQ 183
           D+DEC  +   GE    P C H CHN++GG++CSCR GY L  ++ +C  +
Sbjct: 142 DLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAE 192



 Score = 35.0 bits (79), Expect = 0.037
 Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 33/173 (19%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTH-FDLELSHL--CEYDFVKLSSGAK 84
           G ++S  +P  Y  D    +++    G  L L F   FD++      C YD +++ +  K
Sbjct: 203 GYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGK 262

Query: 85  VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAE------- 137
            +   CG+     +R P  DT     +++D+ F +D S +    G++  Y  E       
Sbjct: 263 NIGEFCGK-----QRPPDLDT---SSNAVDLLFFTDESGDS--RGWKLRYTTEIIKCPQP 312

Query: 138 -DIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGY-------VLHRNKRTCSE 182
             +DE  +     P      +     F  +C+ GY       VLH     C +
Sbjct: 313 KTLDEFTIIQNLQPQYQFRDY-----FIATCKQGYQLIEGNQVLHSFTAVCQD 360


>gi|4502495 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  140 bits (353), Expect = 6e-34
 Identities = 66/160 (41%), Positives = 97/160 (60%), Gaps = 3/160 (1%)

Query: 22  WPEP-VFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS 80
           + EP ++G + SP +P  Y ++ E+ W +  P GY + LYFTH D+ELS  C YD V++ 
Sbjct: 14  YAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQII 73

Query: 81  SGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDID 140
           SG      LCGQ S++   +P  + F    + L + F+SD+SNE+ FTGF A+Y A DI+
Sbjct: 74  SGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDIN 133

Query: 141 ECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
           EC     + P C H C+N +GG++CSC   Y LH + + C
Sbjct: 134 ECTDFV-DVP-CSHFCNNFIGGYFCSCPPEYFLHDDMKNC 171



 Score = 30.0 bits (66), Expect = 1.2
 Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 10/104 (9%)

Query: 26  VFGRLASPGFPGEYANDQERRWTLTAPPGYRL--RLYFTHFDLELSHLCE--YDFVKLSS 81
           + G +ASP +P  Y  +    + +    G+++   L    FD+E +       D +   +
Sbjct: 183 LIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVA 242

Query: 82  GAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEK 125
           G +     CG         PG     +  ++LDI F++D + +K
Sbjct: 243 GDRQFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQK 280


>gi|41393602 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score =  140 bits (353), Expect = 6e-34
 Identities = 66/160 (41%), Positives = 97/160 (60%), Gaps = 3/160 (1%)

Query: 22  WPEP-VFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS 80
           + EP ++G + SP +P  Y ++ E+ W +  P GY + LYFTH D+ELS  C YD V++ 
Sbjct: 14  YAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQII 73

Query: 81  SGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDID 140
           SG      LCGQ S++   +P  + F    + L + F+SD+SNE+ FTGF A+Y A DI+
Sbjct: 74  SGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDIN 133

Query: 141 ECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
           EC     + P C H C+N +GG++CSC   Y LH + + C
Sbjct: 134 ECTDFV-DVP-CSHFCNNFIGGYFCSCPPEYFLHDDMKNC 171



 Score = 30.0 bits (66), Expect = 1.2
 Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 10/104 (9%)

Query: 26  VFGRLASPGFPGEYANDQERRWTLTAPPGYRL--RLYFTHFDLELSHLCE--YDFVKLSS 81
           + G +ASP +P  Y  +    + +    G+++   L    FD+E +       D +   +
Sbjct: 183 LIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVA 242

Query: 82  GAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEK 125
           G +     CG         PG     +  ++LDI F++D + +K
Sbjct: 243 GDRQFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQK 280


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score = 97.8 bits (242), Expect = 5e-21
 Identities = 61/176 (34%), Positives = 85/176 (48%), Gaps = 26/176 (14%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG   T L         G + SPG+P EY  ++   W + AP  YR+ L F  F+LE + 
Sbjct: 620 CGGFITKLN--------GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGND 671

Query: 71  LCEYDFVKLSSG----AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
           +C+YDFV++ SG    AK+    CG E+         +   S  +++ + F+SD +  K 
Sbjct: 672 VCKYDFVEVRSGLSPDAKLHGRFCGSET--------PEVITSQSNNMRVEFKSDNTVSK- 722

Query: 127 FTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
             GF A + + D DEC    G    C H C N  G + C CR GY LH N   C E
Sbjct: 723 -RGFRAHFFS-DKDECAKDNG---GCQHECVNTFGSYLCRCRNGYWLHENGHDCKE 773



 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 17/157 (10%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G++ SP +P +Y   +E  W +T   G+ + L F  F++E    C YD++++  G    +
Sbjct: 473 GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEES 532

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
            ++   CG E  +  +        S  + L + F SD S  K   GF A +  E +DEC 
Sbjct: 533 ALIGHFCGYEKPEDVK--------SSSNRLWMKFVSDGSINK--AGFAANFFKE-VDECS 581

Query: 144 VAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
               +   C+H C N LG + C+C  GY L  +K+ C
Sbjct: 582 WP--DHGGCEHRCVNTLGSYKCACDPGYELAADKKMC 616



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 37/116 (31%), Positives = 61/116 (52%), Gaps = 14/116 (12%)

Query: 26  VFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG--- 82
           V G LASP +P +Y + +E  W +++  G+R++L F  F++E    C YD +++  G   
Sbjct: 783 VEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDS 842

Query: 83  -AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAE 137
            A +L   CG +  D   A         GSS+ + F SD S ++   GF+A ++ E
Sbjct: 843 LAPILGRFCGSKKPDPTVAS--------GSSMFLRFYSDASVQR--KGFQAVHSTE 888



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 14/113 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G  ++PGFP  Y +     W ++  PG ++ L FT  DL  S LC YD+V++  G    A
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +L   CG      ++ P  +   S  S L + FRS  S+     GF A Y A
Sbjct: 420 PLLGRFCG------DKIP--EPLVSTDSRLWVEFRS--SSNILGKGFFAAYEA 462



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 14/102 (13%)

Query: 39   YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVK----LSSGAKVLATLCGQES 94
            Y ++    W + A  GY + L F  F++E    C YD+++      S A  L   CG   
Sbjct: 913  YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSGP 972

Query: 95   TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
                     +  YS G SL I FR+D +  K   GF A Y +
Sbjct: 973  L--------EEIYSAGDSLMIRFRTDDTINK--KGFHARYTS 1004


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score = 96.7 bits (239), Expect = 1e-20
 Identities = 60/176 (34%), Positives = 89/176 (50%), Gaps = 26/176 (14%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG + T L         G + +PG+P EY  ++   W + AP  YR+ + F  F+LE + 
Sbjct: 618 CGGLLTKLN--------GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNE 669

Query: 71  LCEYDFVK----LSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
           +C+YD+V+    LSS +K+    CG E          +   S  +++ I F+SD +  K 
Sbjct: 670 VCKYDYVEIWSGLSSESKLHGKFCGAEV--------PEVITSQFNNMRIEFKSDNTVSK- 720

Query: 127 FTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
             GF+A + + D DEC    G    C H C N +G + C CR G+VLH NK  C E
Sbjct: 721 -KGFKAHFFS-DKDECSKDNG---GCQHECVNTMGSYMCQCRNGFVLHDNKHDCKE 771



 Score = 74.3 bits (181), Expect = 5e-14
 Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 17/157 (10%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G++ SP +P +Y   +E  W +T    Y + L F  F++E    C YD++++  G    +
Sbjct: 471 GQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENS 530

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
            ++   CG +  +  R        S  ++L + F SD +  K   GF A +  E+ DEC 
Sbjct: 531 PLIGRFCGYDKPEDIR--------STSNTLWMKFVSDGTVNK--AGFAANFFKEE-DEC- 578

Query: 144 VAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
            A  +   C+  C N LG + C+C  GY L  ++R+C
Sbjct: 579 -AKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSC 614



 Score = 60.8 bits (146), Expect = 6e-10
 Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 14/114 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G + SP +P +Y + +E  W ++A PG+R++L F+ F++E    C YD +++  G    +
Sbjct: 783 GLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKS 842

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAE 137
            +L  LCG +  D   A G   F        + F SD S ++   GF+A ++ E
Sbjct: 843 PILGRLCGNKIPDPLVATGNKMF--------VRFVSDASVQR--KGFQATHSTE 886



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 38/113 (33%), Positives = 55/113 (48%), Gaps = 14/113 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G L+SPGFP  Y +     W ++  PG ++ L FT  DL  S LC YD++++  G    +
Sbjct: 358 GNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKS 417

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +L   CG      ++ P  +   S  S + I FRS  S+     GF A Y A
Sbjct: 418 PLLGRFCG------DKLP--EVLTSTDSRMWIEFRS--SSNWVGKGFAAVYEA 460



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 13/94 (13%)

Query: 39  YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----AKVLATLCGQES 94
           Y    +  W L +  G RL L F  F++E    C YD+V+L  G    A  L   CG   
Sbjct: 911 YPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCG--- 967

Query: 95  TDTERAPGKDTFYSLGSSLDITFRSDYS-NEKPF 127
                +   +  YS+G S+ I F +D + N+K F
Sbjct: 968 -----SGPPEEIYSIGDSVLIHFHTDDTINKKGF 996


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score = 95.9 bits (237), Expect = 2e-20
 Identities = 60/176 (34%), Positives = 86/176 (48%), Gaps = 26/176 (14%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG   T L         G + SPG+P EY  ++   W L AP  YR+ L F  F+ E + 
Sbjct: 591 CGGFLTKLN--------GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642

Query: 71  LCEYDFVKLSSG----AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
           +C+YDFV++ SG    +K+    CG E          +   S  +++ + F+SD +  K 
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEK--------PEVITSQYNNMRVEFKSDNTVSK- 693

Query: 127 FTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
             GF+A + + D DEC    G    C   C N  G + C CR+G+VLH NK  C E
Sbjct: 694 -KGFKAHFFS-DKDECSKDNG---GCQQDCVNTFGSYECQCRSGFVLHDNKHDCKE 744



 Score = 73.9 bits (180), Expect = 7e-14
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 17/158 (10%)

Query: 27  FGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           +G + SP +P +Y   +   W +    G+ + L F  F++E    C YD++++  G    
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 87  ATL----CGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           +TL    CG E  D  +        S  S L + F SD S  K   GF   +  E +DEC
Sbjct: 503 STLIGRYCGYEKPDDIK--------STSSRLWLKFVSDGSINK--AGFAVNFFKE-VDEC 551

Query: 143 QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
              P     C+  C N LG + CSC  GY L  +KR C
Sbjct: 552 S-RPNRG-GCEQRCLNTLGSYKCSCDPGYELAPDKRRC 587



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 14/114 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G + SP +P +Y + +E  W +++ PG+R++L F   D+E    C YD +++  G    A
Sbjct: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAE 137
            VL   CG +  +   A G   F        + F SD S ++   GF+A +A E
Sbjct: 816 PVLGRFCGSKKPEPVLATGSRMF--------LRFYSDNSVQR--KGFQASHATE 859



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 14/113 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G  +SP +P  Y+      W ++  PG ++ L FT  DL  S LC YD+V++  G    A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +    CG +          +   S  S L + FRS  S+     GF A Y A
Sbjct: 391 PLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGKGFFAVYEA 433



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 14/102 (13%)

Query: 39  YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----AKVLATLCGQES 94
           Y    +  W + A  GY + L F  F++E    C YD+++L  G    A  L   CG   
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-- 941

Query: 95  TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
                 P ++  YS G S+ + F SD +  K   GF   Y +
Sbjct: 942 -----GPPEEV-YSAGDSVLVKFHSDDTITK--KGFHLRYTS 975


>gi|7706083 complement component 1, r subcomponent-like precursor
           [Homo sapiens]
          Length = 487

 Score = 75.1 bits (183), Expect = 3e-14
 Identities = 53/159 (33%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 29  RLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLAT 88
           +L SPG+P  Y   QE    + AP G+ +RL F  FDLE S  C  D V +S      + 
Sbjct: 51  QLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQ 110

Query: 89  LCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP----FTGFEAFYAAEDIDECQV 144
            CGQ+ +   R PG+  F S G SL +TFR+  S+E        GF A Y    ++  Q 
Sbjct: 111 FCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQP 170

Query: 145 ------------APGEAPT-CDHHCHNHLGGFYCSCRAG 170
                       APG+ P    +HC      +Y +  AG
Sbjct: 171 ISEASRGSEAINAPGDNPAKVQNHCQE---PYYQAAAAG 206


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
           sapiens]
          Length = 730

 Score = 73.9 bits (180), Expect = 7e-14
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 17/158 (10%)

Query: 27  FGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           +G + SP +P +Y   +   W +    G+ + L F  F++E    C YD++++  G    
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 87  ATL----CGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           +TL    CG E  D  +        S  S L + F SD S  K   GF   +  E +DEC
Sbjct: 503 STLIGRYCGYEKPDDIK--------STSSRLWLKFVSDGSINK--AGFAVNFFKE-VDEC 551

Query: 143 QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
              P     C+  C N LG + CSC  GY L  +KR C
Sbjct: 552 S-RPNRG-GCEQRCLNTLGSYKCSCDPGYELAPDKRRC 587



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 41/131 (31%), Positives = 64/131 (48%), Gaps = 22/131 (16%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG   T L         G + SPG+P EY  ++   W L AP  YR+ L F  F+ E + 
Sbjct: 591 CGGFLTKLN--------GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642

Query: 71  LCEYDFVKLSSG----AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
           +C+YDFV++ SG    +K+    CG E          +   S  +++ + F+SD +  K 
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEK--------PEVITSQYNNMRVEFKSDNTVSK- 693

Query: 127 FTGFEAFYAAE 137
             GF+A + +E
Sbjct: 694 -KGFKAHFFSE 703



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 14/113 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G  +SP +P  Y+      W ++  PG ++ L FT  DL  S LC YD+V++  G    A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +    CG +          +   S  S L + FRS  S+     GF A Y A
Sbjct: 391 PLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGKGFFAVYEA 433


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
           sapiens]
          Length = 823

 Score = 73.9 bits (180), Expect = 7e-14
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 17/158 (10%)

Query: 27  FGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           +G + SP +P +Y   +   W +    G+ + L F  F++E    C YD++++  G    
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 87  ATL----CGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
           +TL    CG E  D  +        S  S L + F SD S  K   GF   +  E +DEC
Sbjct: 503 STLIGRYCGYEKPDDIK--------STSSRLWLKFVSDGSINK--AGFAVNFFKE-VDEC 551

Query: 143 QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
              P     C+  C N LG + CSC  GY L  +KR C
Sbjct: 552 S-RPNRG-GCEQRCLNTLGSYKCSCDPGYELAPDKRRC 587



 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 22/128 (17%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG   T L         G + SPG+P EY  ++   W L AP  YR+ L F  F+ E + 
Sbjct: 591 CGGFLTKLN--------GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGND 642

Query: 71  LCEYDFVKLSSG----AKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKP 126
           +C+YDFV++ SG    +K+    CG E          +   S  +++ + F+SD +  K 
Sbjct: 643 VCKYDFVEVRSGLTADSKLHGKFCGSEK--------PEVITSQYNNMRVEFKSDNTVSK- 693

Query: 127 FTGFEAFY 134
             GF+A +
Sbjct: 694 -KGFKAHF 700



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 14/113 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G  +SP +P  Y+      W ++  PG ++ L FT  DL  S LC YD+V++  G    A
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +    CG +          +   S  S L + FRS  S+     GF A Y A
Sbjct: 391 PLRGRFCGSKL--------PEPIVSTDSRLWVEFRS--SSNWVGKGFFAVYEA 433


>gi|50659100 regeneration associated muscle protease isoform b [Homo
           sapiens]
          Length = 720

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 50/148 (33%), Positives = 73/148 (49%), Gaps = 29/148 (19%)

Query: 47  WTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----AKVLATLCGQESTDTERAPG 102
           WT+ A PG+ ++L F    LE  ++C+YD+V++  G     +++  +CG E      AP 
Sbjct: 152 WTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE----RPAP- 206

Query: 103 KDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHH---CHNH 159
                S+GSSL + F SD S  K F GF A Y  E+I  C  +P     C H      + 
Sbjct: 207 ---IQSIGSSLHVLFHSDGS--KNFDGFHAIY--EEITACSSSP-----CFHDGTCVLDK 254

Query: 160 LGGFYCSCRAGYVLHR-----NKRTCSE 182
            G + C+C AGY   R      +R CS+
Sbjct: 255 AGSYKCACLAGYTGQRCENLLEERNCSD 282


>gi|50659098 regeneration associated muscle protease isoform a [Homo
           sapiens]
          Length = 737

 Score = 70.5 bits (171), Expect = 8e-13
 Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 24/136 (17%)

Query: 47  WTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----AKVLATLCGQESTDTERAPG 102
           WT+ A PG+ ++L F    LE  ++C+YD+V++  G     +++  +CG E      AP 
Sbjct: 152 WTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE----RPAP- 206

Query: 103 KDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHH---CHNH 159
                S+GSSL + F SD S  K F GF A Y  E+I  C  +P     C H      + 
Sbjct: 207 ---IQSIGSSLHVLFHSDGS--KNFDGFHAIY--EEITACSSSP-----CFHDGTCVLDK 254

Query: 160 LGGFYCSCRAGYVLHR 175
            G + C+C AGY   R
Sbjct: 255 AGSYKCACLAGYTGQR 270


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G  +SP +P  Y N+ +  W +    GYR+ L F++  LE  H C +D+V++  G+   +
Sbjct: 1024 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1083

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             L G+   DT     +  F S  + + I FRSD S +   TGF A+Y
Sbjct: 1084 LLLGKICNDT-----RQIFTSSYNRMTIHFRSDISFQN--TGFLAWY 1123



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 17/111 (15%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
            G  +SP +PG Y N+ +  W +     YR+ + F   D++L   C YD++++  G    +
Sbjct: 1266 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSS 1323

Query: 84   KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             ++A +C            + +F S  + + I F SD+S  +   GF A Y
Sbjct: 1324 PLIARVCD---------GARGSFTSSSNFMSIRFISDHSITR--RGFRAEY 1363


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G  +SP +P  Y N+ +  W +    GYR+ L F++  LE  H C +D+V++  G+   +
Sbjct: 1150 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1209

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             L G+   DT     +  F S  + + I FRSD S +   TGF A+Y
Sbjct: 1210 LLLGKICNDT-----RQIFTSSYNRMTIHFRSDISFQN--TGFLAWY 1249



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 17/111 (15%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
            G  +SP +PG Y N+ +  W +     YR+ + F   D++L   C YD++++  G    +
Sbjct: 1392 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSS 1449

Query: 84   KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             ++A +C            + +F S  + + I F SD+S  +   GF A Y
Sbjct: 1450 PLIARVCD---------GARGSFTSSSNFMSIRFISDHSITR--RGFRAEY 1489


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G  +SP +P  Y N+ +  W +    GYR+ L F++  LE  H C +D+V++  G+   +
Sbjct: 1765 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1824

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             L G+   DT     +  F S  + + I FRSD S +   TGF A+Y
Sbjct: 1825 LLLGKICNDT-----RQIFTSSYNRMTIHFRSDISFQN--TGFLAWY 1864



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 17/111 (15%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
            G  +SP +PG Y N+ +  W +     YR+ + F   D++L   C YD++++  G    +
Sbjct: 2007 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSS 2064

Query: 84   KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             ++A +C            + +F S  + + I F SD+S  +   GF A Y
Sbjct: 2065 PLIARVCD---------GARGSFTSSSNFMSIRFISDHSITR--RGFRAEY 2104


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G  +SP +P  Y N+ +  W +    GYR+ L F++  LE  H C +D+V++  G+   +
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             L G+   DT     +  F S  + + I FRSD S +   TGF A+Y
Sbjct: 1835 LLLGKICNDT-----RQIFTSSYNRMTIHFRSDISFQN--TGFLAWY 1874



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 17/111 (15%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
            G  +SP +PG Y N+ +  W +     YR+ + F   D++L   C YD++++  G    +
Sbjct: 2017 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSS 2074

Query: 84   KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             ++A +C            + +F S  + + I F SD+S  +   GF A Y
Sbjct: 2075 PLIARVCD---------GARGSFTSSSNFMSIRFISDHSITR--RGFRAEY 2114


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 7/107 (6%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G  +SP +P  Y N+ +  W +    GYR+ L F++  LE  H C +D+V++  G+   +
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             L G+   DT     +  F S  + + I FRSD S +   TGF A+Y
Sbjct: 1207 LLLGKICNDT-----RQIFTSSYNRMTIHFRSDISFQN--TGFLAWY 1246



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 17/111 (15%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
            G  +SP +PG Y N+ +  W +     YR+ + F   D++L   C YD++++  G    +
Sbjct: 1389 GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSS 1446

Query: 84   KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             ++A +C            + +F S  + + I F SD+S  +   GF A Y
Sbjct: 1447 PLIARVCD---------GARGSFTSSSNFMSIRFISDHSITR--RGFRAEY 1486


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
           sapiens]
          Length = 1221

 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 10/107 (9%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G   SP +P +Y N Q   WTL AP GY +++ F  FD+E +  C YD + L +G +   
Sbjct: 50  GTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNG-ESQT 108

Query: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             CG  +          +F S  + + ++F SD+S +K   GF A Y
Sbjct: 109 KFCGATAKGL-------SFNSSANEMHVSFSSDFSIQK--KGFNASY 146


>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
           sapiens]
          Length = 1250

 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 10/107 (9%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G   SP +P +Y N Q   WTL AP GY +++ F  FD+E +  C YD + L +G +   
Sbjct: 50  GTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNG-ESQT 108

Query: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             CG  +          +F S  + + ++F SD+S +K   GF A Y
Sbjct: 109 KFCGATAKGL-------SFNSSANEMHVSFSSDFSIQK--KGFNASY 146


>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
           sapiens]
          Length = 1193

 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 10/107 (9%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G   SP +P +Y N Q   WTL AP GY +++ F  FD+E +  C YD + L +G +   
Sbjct: 50  GTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNG-ESQT 108

Query: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             CG  +          +F S  + + ++F SD+S +K   GF A Y
Sbjct: 109 KFCGATAKGL-------SFNSSANEMHVSFSSDFSIQK--KGFNASY 146


>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
           sapiens]
          Length = 1222

 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 10/107 (9%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G   SP +P +Y N Q   WTL AP GY +++ F  FD+E +  C YD + L +G +   
Sbjct: 50  GTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNG-ESQT 108

Query: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
             CG  +          +F S  + + ++F SD+S +K   GF A Y
Sbjct: 109 KFCGATAKGL-------SFNSSANEMHVSFSSDFSIQK--KGFNASY 146


>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
          Length = 3565

 Score = 60.5 bits (145), Expect = 8e-10
 Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 20/137 (14%)

Query: 11   CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            CG   + LG        G + SPGFPG Y N+ +  W ++ P GY   + F +F  E +H
Sbjct: 1975 CGGTLSTLG--------GVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANH 2026

Query: 71   LCEYDFVKLSSGAKVLATLCGQES-TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
                DF+++ +G    + + GQ S TD   A    T  +L     I F SD+S  +   G
Sbjct: 2027 ----DFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETL-----IHFYSDHSQNR--QG 2075

Query: 130  FEAFYAAEDIDECQVAP 146
            F+  Y A ++  C   P
Sbjct: 2076 FKLAYQAYELQNCPDPP 2092



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 16/150 (10%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPGFP EY   ++  W +T PPG+ + + FT    E  +    D++ +  G    +
Sbjct: 2156 GTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVN----DYIAVWDGPDQNS 2211

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFT-GFEAFYAAEDIDECQVAP 146
               G  S +T      +T YS  + + + F SD+SN   F   F AF     + +CQ  P
Sbjct: 2212 PQLGVFSGNT----ALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAF----QLKKCQPPP 2263

Query: 147  G--EAPTCDHHCHNHLGGFY-CSCRAGYVL 173
               +A          +G F    C  GY L
Sbjct: 2264 AVPQAEMLTEDDDFEIGDFVKYQCHPGYTL 2293



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS----SGA 83
           G + SP +P EY N+    W + + PG R+ L F  FD+E     ++DF+ +     S  
Sbjct: 594 GIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVE----PQFDFLAVKDDGISDI 649

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            VL T  G E       P +    S G  + + F+SD+S      GF   Y     +EC
Sbjct: 650 TVLGTFSGNE------VPSQ--LASSGHIVRLEFQSDHSTTG--RGFNITYTTFGQNEC 698



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            GR+ SPG+P  Y N+    W + A PG  + L+F  FD E++H    D +K+  G     
Sbjct: 1288 GRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----DILKVWDGPVDSD 1343

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
             L  + S         +  +S  +SL + F SD+   K  +GF   ++      C
Sbjct: 1344 ILLKEWSGSAL----PEDIHSTFNSLTLQFDSDFFISK--SGFSIQFSTSIAATC 1392



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 4/51 (7%)

Query: 30  LASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS 80
           ++SP FP EY N+ +  WT+ A PG  + L FT F LE      YDF+++S
Sbjct: 219 ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLEIS 265



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 20/160 (12%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
            G + SPGFP  Y N     WT+    G  +++ F  F LE SH    D++ ++   S ++
Sbjct: 940  GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSH----DYLLITEDGSFSE 995

Query: 85   VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQV 144
             +A L G     T +A     F     +  + F SD+S    + GF   ++  D++ C  
Sbjct: 996  PVARLTGSVLPHTIKAGLFGNF-----TAQLRFISDFSIS--YEGFNITFSEYDLEPCD- 1047

Query: 145  APGEAPTCDHHCHNHLG---GFYCSCRAGYVLH-RNKRTC 180
             PG  P        H G       SC  GY L    K TC
Sbjct: 1048 DPG-VPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTC 1086



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 9/109 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+PG Y N Q   W++   P Y + ++   F  E        F   S  + +L 
Sbjct: 2331 GVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLV 2390

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
             L G  +        +  F S  + L + + +D++  K   GF+  YAA
Sbjct: 2391 VLSGNHTE-------QSNFTSRSNQLYLRWSTDHATSK--KGFKIRYAA 2430



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 19/163 (11%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G +  PG+PG Y +     W + A PG+ +++ F  F  E++    YD +++  G    +
Sbjct: 768 GVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YDTLEVRDGPASSS 823

Query: 88  TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
            L G+      +AP      S G+ + + F +D  N +   GF   Y +  ++       
Sbjct: 824 PLIGE--YHGTQAP--QFLISTGNFMYLLFTTD--NSRSSIGFLIHYESVTLESDSCLDP 877

Query: 148 EAPTCDHHCHNHLGGF------YCSCRAGYVLHRNKRTCSEQS 184
             P    + H H G F        SC  GY L  ++    E++
Sbjct: 878 GIPV---NGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERN 917



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SP +P  Y   +E  W +   P + + L F  F++E S    YDF+ +  G    +
Sbjct: 1461 GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFLHIYEGEDSNS 1516

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYS 122
             L G  S    +AP  +   S G+SL + FRSD S
Sbjct: 1517 PLIG--SYQGSQAP--ERIESSGNSLFLAFRSDAS 1547



 Score = 36.2 bits (82), Expect = 0.017
 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 28/178 (15%)

Query: 2   RLLTLL-GLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLY 60
           RLLT   G  CG +    GP       G + SPGFP  Y N     W +      R++L 
Sbjct: 22  RLLTAAKGQNCGGLVQ--GPN------GTIESPGFPHGYPNYANCTWIIITGERNRIQLS 73

Query: 61  FTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPG---KDTFYSLGSSLDITF 117
           F  F LE     ++D + +  G         Q+     R  G     +  S GS L + F
Sbjct: 74  FHTFALEE----DFDILSVYDGQP-------QQGNLKVRLSGFQLPSSIVSTGSILTLWF 122

Query: 118 RSDYSNEKPFTGFEAFYAAEDIDECQVAPGE-APTCDHHCHNHLGG-FYCSCRAGYVL 173
            +D++      GF+A Y       C   PGE      H    ++G     SC  GY+L
Sbjct: 123 TTDFAVSA--QGFKALYEVLPSHTCG-NPGEILKGVLHGTRFNIGDKIRYSCLPGYIL 177



 Score = 36.2 bits (82), Expect = 0.017
 Identities = 37/149 (24%), Positives = 56/149 (37%), Gaps = 15/149 (10%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N+    W +    G  +++    F  E +    +D +++  G  V A
Sbjct: 1812 GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLEIHDGGDVTA 1867

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ---V 144
               G  S  T  A       S  + L + F+SD S      GF   Y    +  CQ   +
Sbjct: 1868 PRLGSFSGTTVPA----LLNSTSNQLYLHFQSDIS--VAAAGFHLEYKTVGLAACQEPAL 1921

Query: 145  APGEAPTCDHHCHNHLGGFYCSCRAGYVL 173
                    D +  N +  F   C  GY L
Sbjct: 1922 PSNSIKIGDRYMVNDVLSF--QCEPGYTL 1948



 Score = 33.5 bits (75), Expect = 0.11
 Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 13/110 (11%)

Query: 28  GRLASPGFPGEYANDQERRWTL-TAPPGYRLRLYFTHFDLELSH--LCEYDFVKLSSGAK 84
           G + SP +P +Y ++    W + T  P   ++L F  F+LE  +  L   D  K+     
Sbjct: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480

Query: 85  VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
           VL  L G            D   S+ + + +  +SD S   P  GF+A Y
Sbjct: 481 VLYVLTGSSV--------PDLIVSMSNQMWLHLQSDDSIGSP--GFKAVY 520



 Score = 32.3 bits (72), Expect = 0.24
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 10/109 (9%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SP +P  Y   Q   +++T P  + +   F +F   L+ L E  F    + A++L+
Sbjct: 1635 GVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-FDGTHAQARLLS 1693

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
            +L G  S +T           L +S  I  R    +     GF   Y A
Sbjct: 1694 SLSGSHSGET---------LPLATSNQILLRFSAKSGASARGFHFVYQA 1733



 Score = 30.8 bits (68), Expect = 0.69
 Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 19/159 (11%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G L SP FP  Y N+ E  + +    G  + L    F      L E D +K+  G    +
Sbjct: 1114 GTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSF-----QLFEGDTLKVYDGKDSSS 1168

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
               G   T T+         S  + L + F ++ S+     GF+  Y + D+ +C+  PG
Sbjct: 1169 RPLG---TFTKNELLGLILNSTSNHLWLEFNTNGSDTD--QGFQLTYTSFDLVKCE-DPG 1222

Query: 148  EAPTCDHHCHNHLGGF-----YCSCRAGYVLH-RNKRTC 180
              P   +   +  G F       SC  GY +H  N  TC
Sbjct: 1223 -IPNYGYRIRDE-GHFTDTVVLYSCNPGYAMHGSNTLTC 1259


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
          Length = 3667

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPGFPG Y +  +  WT+  P G+ + L F +F  E  H    D++++ SG+   +
Sbjct: 2080 GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH----DYLEVRSGSSETS 2135

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            T+ G+ S    + P   + +S      + F SDYS  K   GF   Y A  +  C
Sbjct: 2136 TVIGRLS--GPQIP--SSLFSTTHETSLYFHSDYSQNK--QGFHIVYQAYQLQSC 2184



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 19/137 (13%)

Query: 10   LCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELS 69
            LCG   T +         G + SPG+P EY N Q+  W +  PPG  + + FT    E  
Sbjct: 2242 LCGGNITAMN--------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2293

Query: 70   HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
                YDF+ +  G    +   GQ S +T      ++ YS  + + I F SD++    F  
Sbjct: 2294 ----YDFITVWDGPDQNSPQIGQFSGNT----ALESVYSTSNQILIKFHSDFTTSGFFV- 2344

Query: 130  FEAFYAAEDIDECQVAP 146
                Y A  +  CQ  P
Sbjct: 2345 --LSYHAYQLRVCQPPP 2359



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 18/176 (10%)

Query: 11   CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            CG+   P G  +  P  G + SPG+PG Y +     W + A PG+ +++ F  F  EL+ 
Sbjct: 851  CGA---PCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN- 905

Query: 71   LCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
               YD +++  G  +L+ L G  S +  + P     +S  + + + F +D  N +   GF
Sbjct: 906  ---YDVLEVHDGPNLLSPLLG--SYNGTQVP--QFLFSSSNFIYLLFTTD--NSRSNNGF 956

Query: 131  EAFYAAEDIDECQ-VAPGEAPTCDHHCHNHLGG--FYCSCRAGYVL-HRNKRTCSE 182
            +  Y +  ++    + PG       + H+   G     SC +GY L H     C +
Sbjct: 957  KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 1012



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 21/152 (13%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SP FP  Y + ++  WT+T    Y + L F  F +E +    YDF+ +  G    +
Sbjct: 1557 GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNS 1612

Query: 88   TLCG--QESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC--- 142
             L G  Q+S   ER        S  +++ + FRSD S    +TGF   Y A+  + C   
Sbjct: 1613 PLIGSFQDSKLPER------IESSSNTMHLAFRSDGS--VSYTGFHLEYKAKLRESCFDP 1664

Query: 143  -QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVL 173
              +  G     D+   + +  +YC   AGYVL
Sbjct: 1665 GNIMNGTRLGMDYKLGSTV-TYYCD--AGYVL 1693



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G + SP +P  Y N+    WT+ + PG R+ L F  FDLE     ++DF+ +  G    +
Sbjct: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 745

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            +L T  G E       P   T  S    L + F++D+S      GF   Y     +EC
Sbjct: 746 PILGTFTGAE------VPSHLT--SNSHILRLEFQADHSMSG--RGFNITYNTFGHNEC 794



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G ++SP FP EY N+ +  WT+ A PG  + L FT F +E     +YD++++        
Sbjct: 210 GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLEIEGSEPPTI 265

Query: 88  TLCG 91
            L G
Sbjct: 266 WLSG 269



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 18/43 (41%), Positives = 23/43 (53%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            GR+ SPG+P  Y N+    W +   PG  + L F  FD E SH
Sbjct: 1384 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASH 1426



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N Q   W+++   GY + ++   F  E     E+D +++  G  + +
Sbjct: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQS 2482

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
             +    S D   A       S G  + + + +D+ N K   GF   Y A
Sbjct: 2483 PVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNK--KGFRIRYIA 2526



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG 82
          G + SPGFP  Y N     W + A    R+++ F  F LE     EYD++ L  G
Sbjct: 34 GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLSLYDG 84



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 16/151 (10%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G L SP +P  Y N+ E  +++    G  + +    F     HL + D +K+  G     
Sbjct: 1210 GILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF-----HLAQGDVLKIYDGKDKTT 1264

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
             L G  +  + R     T  S  + L + F SD   E    GF+  Y + ++  C+  PG
Sbjct: 1265 HLLGAFTGASMRGL---TLSSTSNQLWLEFNSD--TEGTDEGFQLVYTSFELSHCE-DPG 1318

Query: 148  EAPTCDHHC--HNHLGG--FYCSCRAGYVLH 174
              P   +      H  G      C  GY LH
Sbjct: 1319 -IPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1348



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N+    W +T P G  +++    F  E +    +D +    G    A
Sbjct: 1908 GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNA 1963

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G  S  T          S  ++L + F+SD S      GF   Y A  +D C
Sbjct: 1964 PRLGSYSGTTI----PHLLNSTSNNLYLNFQSDISVSA--AGFHLEYTAIGLDSC 2012



 Score = 36.2 bits (82), Expect = 0.017
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
            G + SPG+P  Y N     WT+    G  ++  F  F LE  H    D++ ++   S  +
Sbjct: 1036 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH----DYLLITENGSFTQ 1091

Query: 85   VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
             LA L G +   T  A     F +      + F SD+S    + GF   ++  +++ C+
Sbjct: 1092 PLARLTGSDLPPTINAGLYGNFRA-----QLRFISDFSIS--YEGFNITFSEYNLEPCE 1143



 Score = 34.7 bits (78), Expect = 0.048
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 15/119 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYR-LRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           G   SP FP +Y ++ +  W +TA    + +++ F  FDLE+     YD + +  G +V 
Sbjct: 517 GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG----YDTLTIGDGGEV- 571

Query: 87  ATLCGQESTDTERAPGK---DTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G   T  +   G    D   S+ S + +  ++D S      GF+  Y   + + C
Sbjct: 572 ----GDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGS--VGFKVNYKEIEKESC 624


>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
            sapiens]
          Length = 3538

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPGFPG Y +  +  WT+  P G+ + L F +F  E  H    D++++ SG+   +
Sbjct: 2016 GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH----DYLEVRSGSSETS 2071

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            T+ G+ S    + P   + +S      + F SDYS  K   GF   Y A  +  C
Sbjct: 2072 TVIGRLS--GPQIP--SSLFSTTHETSLYFHSDYSQNK--QGFHIVYQAYQLQSC 2120



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 19/137 (13%)

Query: 10   LCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELS 69
            LCG   T +         G + SPG+P EY N Q+  W +  PPG  + + FT    E  
Sbjct: 2178 LCGGNITAMN--------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2229

Query: 70   HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
                YDF+ +  G    +   GQ S +T      ++ YS  + + I F SD++    F  
Sbjct: 2230 ----YDFITVWDGPDQNSPQIGQFSGNT----ALESVYSTSNQILIKFHSDFTTSGFFV- 2280

Query: 130  FEAFYAAEDIDECQVAP 146
                Y A  +  CQ  P
Sbjct: 2281 --LSYHAYQLRVCQPPP 2295



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 18/176 (10%)

Query: 11  CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
           CG+   P G  +  P  G + SPG+PG Y +     W + A PG+ +++ F  F  EL+ 
Sbjct: 787 CGA---PCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN- 841

Query: 71  LCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
              YD +++  G  +L+ L G  S +  + P     +S  + + + F +D  N +   GF
Sbjct: 842 ---YDVLEVHDGPNLLSPLLG--SYNGTQVP--QFLFSSSNFIYLLFTTD--NSRSNNGF 892

Query: 131 EAFYAAEDIDECQ-VAPGEAPTCDHHCHNHLGG--FYCSCRAGYVL-HRNKRTCSE 182
           +  Y +  ++    + PG       + H+   G     SC +GY L H     C +
Sbjct: 893 KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 948



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 21/152 (13%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SP FP  Y + ++  WT+T    Y + L F  F +E +    YDF+ +  G    +
Sbjct: 1493 GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNS 1548

Query: 88   TLCG--QESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC--- 142
             L G  Q+S   ER        S  +++ + FRSD S    +TGF   Y A+  + C   
Sbjct: 1549 PLIGSFQDSKLPER------IESSSNTMHLAFRSDGS--VSYTGFHLEYKAKLRESCFDP 1600

Query: 143  -QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVL 173
              +  G     D+   + +  +YC   AGYVL
Sbjct: 1601 GNIMNGTRLGMDYKLGSTV-TYYCD--AGYVL 1629



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G + SP +P  Y N+    WT+ + PG R+ L F  FDLE     ++DF+ +  G    +
Sbjct: 626 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 681

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            +L T  G E       P   T  S    L + F++D+S      GF   Y     +EC
Sbjct: 682 PILGTFTGAE------VPSHLT--SNSHILRLEFQADHSMSG--RGFNITYNTFGHNEC 730



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G ++SP FP EY N+ +  WT+ A PG  + L FT F +E     +YD++++        
Sbjct: 250 GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLEIEGSEPPTI 305

Query: 88  TLCG 91
            L G
Sbjct: 306 WLSG 309



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 18/43 (41%), Positives = 23/43 (53%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            GR+ SPG+P  Y N+    W +   PG  + L F  FD E SH
Sbjct: 1320 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASH 1362



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N Q   W+++   GY + ++   F  E     E+D +++  G  + +
Sbjct: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQS 2418

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
             +    S D   A       S G  + + + +D+ N K   GF   Y A
Sbjct: 2419 PVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNK--KGFRIRYIA 2462



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG 82
           G + SPGFP  Y N     W + A    R+++ F  F LE     EYD++ L  G
Sbjct: 74  GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLSLYDG 124



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 16/151 (10%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G L SP +P  Y N+ E  +++    G  + +    F     HL + D +K+  G     
Sbjct: 1146 GILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF-----HLAQGDVLKIYDGKDKTT 1200

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
             L G  +  + R     T  S  + L + F SD   E    GF+  Y + ++  C+  PG
Sbjct: 1201 HLLGAFTGASMRGL---TLSSTSNQLWLEFNSD--TEGTDEGFQLVYTSFELSHCE-DPG 1254

Query: 148  EAPTCDHHC--HNHLGG--FYCSCRAGYVLH 174
              P   +      H  G      C  GY LH
Sbjct: 1255 -IPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1284



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N+    W +T P G  +++    F  E +    +D +    G    A
Sbjct: 1844 GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNA 1899

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G  S  T          S  ++L + F+SD S      GF   Y A  +D C
Sbjct: 1900 PRLGSYSGTTI----PHLLNSTSNNLYLNFQSDISVSA--AGFHLEYTAIGLDSC 1948



 Score = 36.2 bits (82), Expect = 0.017
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
            G + SPG+P  Y N     WT+    G  ++  F  F LE  H    D++ ++   S  +
Sbjct: 972  GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH----DYLLITENGSFTQ 1027

Query: 85   VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
             LA L G +   T  A     F +      + F SD+S    + GF   ++  +++ C+
Sbjct: 1028 PLARLTGSDLPPTINAGLYGNFRA-----QLRFISDFSIS--YEGFNITFSEYNLEPCE 1079



 Score = 34.7 bits (78), Expect = 0.048
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 15/119 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYR-LRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           G   SP FP +Y ++ +  W +TA    + +++ F  FDLE+     YD + +  G +V 
Sbjct: 453 GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG----YDTLTIGDGGEV- 507

Query: 87  ATLCGQESTDTERAPGK---DTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G   T  +   G    D   S+ S + +  ++D S      GF+  Y   + + C
Sbjct: 508 ----GDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGS--VGFKVNYKEIEKESC 560


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
          Length = 3707

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPGFPG Y +  +  WT+  P G+ + L F +F  E  H    D++++ SG+   +
Sbjct: 2120 GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH----DYLEVRSGSSETS 2175

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            T+ G+ S    + P   + +S      + F SDYS  K   GF   Y A  +  C
Sbjct: 2176 TVIGRLS--GPQIP--SSLFSTTHETSLYFHSDYSQNK--QGFHIVYQAYQLQSC 2224



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 19/137 (13%)

Query: 10   LCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELS 69
            LCG   T +         G + SPG+P EY N Q+  W +  PPG  + + FT    E  
Sbjct: 2282 LCGGNITAMN--------GTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPI 2333

Query: 70   HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTG 129
                YDF+ +  G    +   GQ S +T      ++ YS  + + I F SD++    F  
Sbjct: 2334 ----YDFITVWDGPDQNSPQIGQFSGNT----ALESVYSTSNQILIKFHSDFTTSGFFV- 2384

Query: 130  FEAFYAAEDIDECQVAP 146
                Y A  +  CQ  P
Sbjct: 2385 --LSYHAYQLRVCQPPP 2399



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 18/176 (10%)

Query: 11   CGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            CG+   P G  +  P  G + SPG+PG Y +     W + A PG+ +++ F  F  EL+ 
Sbjct: 891  CGA---PCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN- 945

Query: 71   LCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGF 130
               YD +++  G  +L+ L G  S +  + P     +S  + + + F +D  N +   GF
Sbjct: 946  ---YDVLEVHDGPNLLSPLLG--SYNGTQVP--QFLFSSSNFIYLLFTTD--NSRSNNGF 996

Query: 131  EAFYAAEDIDECQ-VAPGEAPTCDHHCHNHLGG--FYCSCRAGYVL-HRNKRTCSE 182
            +  Y +  ++    + PG       + H+   G     SC +GY L H     C +
Sbjct: 997  KIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 1052



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 21/152 (13%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SP FP  Y + ++  WT+T    Y + L F  F +E +    YDF+ +  G    +
Sbjct: 1597 GFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNS 1652

Query: 88   TLCG--QESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC--- 142
             L G  Q+S   ER        S  +++ + FRSD S    +TGF   Y A+  + C   
Sbjct: 1653 PLIGSFQDSKLPER------IESSSNTMHLAFRSDGS--VSYTGFHLEYKAKLRESCFDP 1704

Query: 143  -QVAPGEAPTCDHHCHNHLGGFYCSCRAGYVL 173
              +  G     D+   + +  +YC   AGYVL
Sbjct: 1705 GNIMNGTRLGMDYKLGSTV-TYYCD--AGYVL 1733



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 18/119 (15%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----A 83
           G + SP +P  Y N+    WT+ + PG R+ L F  FDLE     ++DF+ +  G    +
Sbjct: 730 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 785

Query: 84  KVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
            +L T  G E       P   T  S    L + F++D+S      GF   Y     +EC
Sbjct: 786 PILGTFTGAE------VPSHLT--SNSHILRLEFQADHSMSG--RGFNITYNTFGHNEC 834



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
           G ++SP FP EY N+ +  WT+ A PG  + L FT F +E     +YD++++        
Sbjct: 250 GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KYDYLEIEGSEPPTI 305

Query: 88  TLCG 91
            L G
Sbjct: 306 WLSG 309



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 18/43 (41%), Positives = 23/43 (53%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSH 70
            GR+ SPG+P  Y N+    W +   PG  + L F  FD E SH
Sbjct: 1424 GRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASH 1466



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N Q   W+++   GY + ++   F  E     E+D +++  G  + +
Sbjct: 2467 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----EFDVLQVYDGPNIQS 2522

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAA 136
             +    S D   A       S G  + + + +D+ N K   GF   Y A
Sbjct: 2523 PVLISLSGDYSSA---FNITSNGHEVFLQWSADHGNNK--KGFRIRYIA 2566



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG 82
           G + SPGFP  Y N     W + A    R+++ F  F LE     EYD++ L  G
Sbjct: 74  GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE----EYDYLSLYDG 124



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 16/151 (10%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G L SP +P  Y N+ E  +++    G  + +    F     HL + D +K+  G     
Sbjct: 1250 GILLSPNYPLNYENNHECIYSIQVQAGKGINISARTF-----HLAQGDVLKIYDGKDKTT 1304

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPG 147
             L G  +  + R     T  S  + L + F SD   E    GF+  Y + ++  C+  PG
Sbjct: 1305 HLLGAFTGASMRGL---TLSSTSNQLWLEFNSD--TEGTDEGFQLVYTSFELSHCE-DPG 1358

Query: 148  EAPTCDHHC--HNHLGG--FYCSCRAGYVLH 174
              P   +      H  G      C  GY LH
Sbjct: 1359 -IPQFGYKISDQGHFAGSTIIYGCNPGYTLH 1388



 Score = 37.0 bits (84), Expect = 0.010
 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 10/115 (8%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
            G + SPG+P  Y N+    W +T P G  +++    F  E +    +D +    G    A
Sbjct: 1948 GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNA 2003

Query: 88   TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G  S  T          S  ++L + F+SD S      GF   Y A  +D C
Sbjct: 2004 PRLGSYSGTTI----PHLLNSTSNNLYLNFQSDISVSA--AGFHLEYTAIGLDSC 2052



 Score = 36.2 bits (82), Expect = 0.017
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 14/119 (11%)

Query: 28   GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS---SGAK 84
            G + SPG+P  Y N     WT+    G  ++  F  F LE  H    D++ ++   S  +
Sbjct: 1076 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH----DYLLITENGSFTQ 1131

Query: 85   VLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQ 143
             LA L G +   T  A     F +      + F SD+S    + GF   ++  +++ C+
Sbjct: 1132 PLARLTGSDLPPTINAGLYGNFRA-----QLRFISDFSIS--YEGFNITFSEYNLEPCE 1183



 Score = 34.7 bits (78), Expect = 0.048
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 15/119 (12%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYR-LRLYFTHFDLELSHLCEYDFVKLSSGAKVL 86
           G   SP FP +Y ++ +  W +TA    + +++ F  FDLE+     YD + +  G +V 
Sbjct: 557 GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG----YDTLTIGDGGEV- 611

Query: 87  ATLCGQESTDTERAPGK---DTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC 142
               G   T  +   G    D   S+ S + +  ++D S      GF+  Y   + + C
Sbjct: 612 ----GDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGS--VGFKVNYKEIEKESC 664


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 7/115 (6%)

Query: 12  GSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAP-PGYRLRLYFT-HFDLELS 69
           G    P G +      G + SPG+P +Y + Q   W + AP P  ++ L F  HF++E  
Sbjct: 22  GQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-K 80

Query: 70  HLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNE 124
           H C+YDF+++  G    A L G+   +   AP   T  S GS L I F SDY+ +
Sbjct: 81  HDCKYDFIEIRDGDSESADLLGKHCGNI--AP--PTIISSGSMLYIKFTSDYARQ 131



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 18/116 (15%)

Query: 28  GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL------CEYDFVKLSS 81
           G + SPGFP +Y ++ +  +T+ A P   + L F  FDLE   L      C+YD++ +  
Sbjct: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWD 217

Query: 82  GAKVLATLCGQESTDTERAPGKDTFYSLGSS---LDITFRSDYSNEKPFTGFEAFY 134
           G   +  L G+         G  T   L SS   L +TF +D +  K   GF A Y
Sbjct: 218 GIPHVGPLIGKYC-------GTKTPSELRSSTGILSLTFHTDMAVAK--DGFSARY 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,594,204
Number of Sequences: 37866
Number of extensions: 408250
Number of successful extensions: 2232
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 1288
Number of HSP's gapped (non-prelim): 922
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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