Search of human proteins with 211904190

Search of human proteins with 211904190

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|211904190 hypothetical protein LOC149478 [Homo sapiens]
         (291 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|211904190 hypothetical protein LOC149478 [Homo sapiens]            573   e-164
gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]    99   3e-21
gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]    99   3e-21
gi|225543407 BTB domain protein BDPL [Homo sapiens]                    82   4e-16
gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo s...    80   2e-15
gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo ...    80   2e-15
gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens]     79   4e-15
gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens]     79   4e-15
gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]               76   3e-14
gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens]    76   4e-14
gi|40807500 kelch-like 20 [Homo sapiens]                               70   2e-12
gi|5174473 intracisternal A particle-promoted polypeptide isofor...    68   8e-12
gi|109150407 kelch-like 6 [Homo sapiens]                               68   8e-12
gi|223890235 intracisternal A particle-promoted polypeptide isof...    68   8e-12
gi|56117834 speckle-type POZ protein [Homo sapiens]                    67   1e-11
gi|56117832 speckle-type POZ protein [Homo sapiens]                    67   1e-11
gi|56117830 speckle-type POZ protein [Homo sapiens]                    67   1e-11
gi|56117828 speckle-type POZ protein [Homo sapiens]                    67   1e-11
gi|4507183 speckle-type POZ protein [Homo sapiens]                     67   1e-11
gi|56117836 speckle-type POZ protein [Homo sapiens]                    67   1e-11
gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo...    67   2e-11
gi|38327518 BTB and kelch domain containing 3 [Homo sapiens]           66   4e-11
gi|38327516 BTB and kelch domain containing 3 [Homo sapiens]           66   4e-11
gi|24432026 kelch-like [Homo sapiens]                                  65   5e-11
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]                     64   1e-10
gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]                     63   3e-10
gi|55770880 kelch-like 5 isoform 3 [Homo sapiens]                      63   3e-10
gi|65289292 kelch-like 5 isoform 1 [Homo sapiens]                      63   3e-10
gi|8922854 kelch-like 26 [Homo sapiens]                                63   3e-10
gi|23397572 kelch-like 34 [Homo sapiens]                               63   3e-10

>gi|211904190 hypothetical protein LOC149478 [Homo sapiens]
          Length = 291

 Score =  573 bits (1478), Expect = e-164
 Identities = 291/291 (100%), Positives = 291/291 (100%)

Query: 1   MEPLGLVVHGKAEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLL 60
           MEPLGLVVHGKAEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLL
Sbjct: 1   MEPLGLVVHGKAEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLL 60

Query: 61  GTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELC 120
           GTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELC
Sbjct: 61  GTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELC 120

Query: 121 LQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPL 180
           LQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPL
Sbjct: 121 LQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPL 180

Query: 181 LRSDKLCVDEAELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQN 240
           LRSDKLCVDEAELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQN
Sbjct: 181 LRSDKLCVDEAELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQN 240

Query: 241 RQEPLIPVEQIVEAWKCHALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291
           RQEPLIPVEQIVEAWKCHALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK
Sbjct: 241 RQEPLIPVEQIVEAWKCHALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291


>gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
          Length = 612

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 21/271 (7%)

Query: 16  SAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVP-SPVVL 74
           S  + +L+    Y DV FVV  E++   AHR +LA RC +F+ LL        P + + L
Sbjct: 23  SEHIGALLIGEEYGDVTFVV--EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPL 80

Query: 75  STVPTEAFLAVLEFLYTNSVKLYRHS---VLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
                EAF  +L+++YT    L       +L+ L+ A +YG  EL +   +++  +L++ 
Sbjct: 81  QDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQ 140

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEA 191
            VC    VA  + L +L   C  F++ ++QE L + GFL LS  ALL ++  D     E 
Sbjct: 141 NVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEK 200

Query: 192 ELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQI 251
           ++  A  +W +  +        E  A +++ +RL L++  EL  +    R   L+  + I
Sbjct: 201 DIFLALLNWCKHNS-------KENHAEIMQAVRLPLMSLTELLNVV---RPSGLLSPDAI 250

Query: 252 VEAWKCHALRRGDEARGAPCRRRRGTLPREH 282
           ++A K  +     E+R      R   +P E+
Sbjct: 251 LDAIKVRS-----ESRDMDLNYRGMLIPEEN 276


>gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
          Length = 612

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 21/271 (7%)

Query: 16  SAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVP-SPVVL 74
           S  + +L+    Y DV FVV  E++   AHR +LA RC +F+ LL        P + + L
Sbjct: 23  SEHIGALLIGEEYGDVTFVV--EKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPL 80

Query: 75  STVPTEAFLAVLEFLYTNSVKLYRHS---VLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
                EAF  +L+++YT    L       +L+ L+ A +YG  EL +   +++  +L++ 
Sbjct: 81  QDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQ 140

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEA 191
            VC    VA  + L +L   C  F++ ++QE L + GFL LS  ALL ++  D     E 
Sbjct: 141 NVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEK 200

Query: 192 ELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQI 251
           ++  A  +W +  +        E  A +++ +RL L++  EL  +    R   L+  + I
Sbjct: 201 DIFLALLNWCKHNS-------KENHAEIMQAVRLPLMSLTELLNVV---RPSGLLSPDAI 250

Query: 252 VEAWKCHALRRGDEARGAPCRRRRGTLPREH 282
           ++A K  +     E+R      R   +P E+
Sbjct: 251 LDAIKVRS-----ESRDMDLNYRGMLIPEEN 276


>gi|225543407 BTB domain protein BDPL [Homo sapiens]
          Length = 485

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 70/277 (25%), Positives = 122/277 (44%), Gaps = 12/277 (4%)

Query: 22  LVNNPRYSDVCFVVGQE--RQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPT 79
           + NN   +DV FVVG     + V AH+ +LA   + F  +   +    V S + +  V  
Sbjct: 76  MFNNELMADVHFVVGPPGATRTVPAHKYVLAVGSSVFYAMFYGDLAE-VKSEIHIPDVEP 134

Query: 80  EAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQV 139
            AFL +L+++Y++ + L   +VL  L AA +Y +  L + C+ F+   L+    C  L  
Sbjct: 135 AAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQ 194

Query: 140 AVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARS 199
           +  F   +L +RC   I+A ++ ALR+ GF E+    L  ++  + L   EA +  A  +
Sbjct: 195 SRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLN 254

Query: 200 WA-----RVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQIVEA 254
           WA     R G  +  R    V     + L L  +    L        Q  ++ +E+    
Sbjct: 255 WAEAECKRQGLPITPRNKRHVLG---RALYLVRIPTMTLEEFANGAAQSDILTLEETHSI 311

Query: 255 WKCHALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291
           +  +           P  +R+G  P+  HRF   +++
Sbjct: 312 FLWYTATNKPRL-DFPLTKRKGLAPQRCHRFQSSAYR 347


>gi|7662402 BTB/POZ domain containing protein 3 isoform a [Homo
           sapiens]
          Length = 522

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 67/274 (24%), Positives = 119/274 (43%), Gaps = 6/274 (2%)

Query: 22  LVNNPRYSDVCFVVGQE--RQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPT 79
           + NN   +DV FVVG     Q +  H+ +LA   + F  +   E        + +  V  
Sbjct: 113 MFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAED-KDEIRIPDVEP 171

Query: 80  EAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQV 139
            AFLA+L+++Y + + L   +VL  L AA +Y +  L   C+ F+   L     C  L  
Sbjct: 172 AAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQ 231

Query: 140 AVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARS 199
           +  F    L +RC   I+A ++ AL++ GF ++    L  +LR + L   E  +  AA +
Sbjct: 232 SCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALN 291

Query: 200 WARVGA--AVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQIVEAWKC 257
           WA V      L   +      + K L L  +    L        Q  ++ + +  + +  
Sbjct: 292 WAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLW 351

Query: 258 HALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291
           +   +  E +    + R+G +P+  HRF   +++
Sbjct: 352 YTAAKKPELQFV-SKARKGLVPQRCHRFQSCAYR 384


>gi|31317209 BTB/POZ domain containing protein 3 isoform b [Homo
           sapiens]
          Length = 461

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 67/274 (24%), Positives = 119/274 (43%), Gaps = 6/274 (2%)

Query: 22  LVNNPRYSDVCFVVGQE--RQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPT 79
           + NN   +DV FVVG     Q +  H+ +LA   + F  +   E        + +  V  
Sbjct: 52  MFNNDLMADVHFVVGPPGGTQRLPGHKYVLAVGSSVFHAMFYGELAED-KDEIRIPDVEP 110

Query: 80  EAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQV 139
            AFLA+L+++Y + + L   +VL  L AA +Y +  L   C+ F+   L     C  L  
Sbjct: 111 AAFLAMLKYIYCDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETSLSAKNACVLLSQ 170

Query: 140 AVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARS 199
           +  F    L +RC   I+A ++ AL++ GF ++    L  +LR + L   E  +  AA +
Sbjct: 171 SCLFEEPDLTQRCWEVIDAQAELALKSEGFCDIDFQTLESILRRETLNAKEIVVFEAALN 230

Query: 200 WARVGA--AVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQIVEAWKC 257
           WA V      L   +      + K L L  +    L        Q  ++ + +  + +  
Sbjct: 231 WAEVECQRQDLALSIENKRKVLGKALYLIRIPTMALDDFANGAAQSGVLTLNETNDIFLW 290

Query: 258 HALRRGDEARGAPCRRRRGTLPREHHRFLDLSFK 291
           +   +  E +    + R+G +P+  HRF   +++
Sbjct: 291 YTAAKKPELQFV-SKARKGLVPQRCHRFQSCAYR 323


>gi|59814146 BTB (POZ) domain containing 1 isoform 2 [Homo sapiens]
          Length = 385

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 14/227 (6%)

Query: 22  LVNNPRYSDVCFVVGQER--------QEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVV 73
           L N+   SDV FV+G+ R        Q + AHR +LA     F  +          + + 
Sbjct: 62  LFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMAT-TSAEIE 120

Query: 74  LSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLV 133
           L  V   AFLA+L FLY++ V++   +V+  L  A +Y +  L   C++F+ K L  D  
Sbjct: 121 LPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNA 180

Query: 134 CEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAEL 193
              L  A  F   QL   C+  I+  + +A+   GF ++    L  +L  D L + E+ L
Sbjct: 181 FMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRL 240

Query: 194 VRAARSWARVGAAVLERPVA-----EVAAPVVKELRLALLAPAELSA 235
             A   WA       + PV      +V    +  +R  L+   E +A
Sbjct: 241 FGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAA 287


>gi|13376848 BTB (POZ) domain containing 1 isoform 1 [Homo sapiens]
          Length = 482

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 63/227 (27%), Positives = 99/227 (43%), Gaps = 14/227 (6%)

Query: 22  LVNNPRYSDVCFVVGQER--------QEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVV 73
           L N+   SDV FV+G+ R        Q + AHR +LA     F  +          + + 
Sbjct: 62  LFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMAT-TSAEIE 120

Query: 74  LSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLV 133
           L  V   AFLA+L FLY++ V++   +V+  L  A +Y +  L   C++F+ K L  D  
Sbjct: 121 LPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNA 180

Query: 134 CEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAEL 193
              L  A  F   QL   C+  I+  + +A+   GF ++    L  +L  D L + E+ L
Sbjct: 181 FMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRL 240

Query: 194 VRAARSWARVGAAVLERPVA-----EVAAPVVKELRLALLAPAELSA 235
             A   WA       + PV      +V    +  +R  L+   E +A
Sbjct: 241 FGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAA 287


>gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]
          Length = 525

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 54/182 (29%), Positives = 86/182 (47%), Gaps = 3/182 (1%)

Query: 22  LVNNPRYSDVCFVVGQ--ERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPT 79
           L NN    DV F+VG+    Q + AHR +LA     F  +          + + L  V  
Sbjct: 110 LFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMAT-TSTEIELPDVEP 168

Query: 80  EAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQV 139
            AFLA+L+FLY++ V++   +V+  L  A +Y +  L   C++F+ K L  D     L  
Sbjct: 169 AAFLALLKFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQ 228

Query: 140 AVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELVRAARS 199
           A  F   QL   C+  I+ ++ +A+   GF ++    L+ +L  D L + E  L  A   
Sbjct: 229 ARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVR 288

Query: 200 WA 201
           W+
Sbjct: 289 WS 290


>gi|151108435 BTB (POZ) domain containing 9 isoform b [Homo sapiens]
          Length = 544

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 18/214 (8%)

Query: 72  VVLSTVPTEAFLAVLEFLYTNSVKLYRHS---VLEVLTAAVEYGLEELRELCLQFVVKVL 128
           + L     EAF  +L+++YT    L       +L+ L+ A +YG  EL +   +++  +L
Sbjct: 10  IPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTIL 69

Query: 129 DVDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV 188
           ++  VC    VA  + L +L   C  F++ ++QE L + GFL LS  ALL ++  D    
Sbjct: 70  NIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAA 129

Query: 189 DEAELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPV 248
            E ++  A  +W +  +        E  A +++ +RL L++  EL  +    R   L+  
Sbjct: 130 PEKDIFLALLNWCKHNS-------KENHAEIMQAVRLPLMSLTELLNVV---RPSGLLSP 179

Query: 249 EQIVEAWKCHALRRGDEARGAPCRRRRGTLPREH 282
           + I++A K  +     E+R      R   +P E+
Sbjct: 180 DAILDAIKVRS-----ESRDMDLNYRGMLIPEEN 208


>gi|40807500 kelch-like 20 [Homo sapiens]
          Length = 609

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 53/202 (26%), Positives = 98/202 (48%), Gaps = 7/202 (3%)

Query: 30  DVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFL 89
           DV  VVG ++  ++AHR +L+    +F+ +   E      + VV+  +   A   +++F 
Sbjct: 69  DVVLVVGAKK--IYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFA 126

Query: 90  YTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQ 149
           YT+ + +   +V  +L AA    L E++E C +F+ + LD          A T    +L 
Sbjct: 127 YTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELL 186

Query: 150 ERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DEAELVRAARSWARVGAAVL 208
                F + + QE + +  F+ L A  L+ ++ SD+L V  E ++  A  +W +   ++ 
Sbjct: 187 RIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKY--SIQ 244

Query: 209 ERPVAEVAAPVVKELRLALLAP 230
           ER        V++ +RL LL+P
Sbjct: 245 ER--RPQLPQVLQHVRLPLLSP 264


>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
           [Homo sapiens]
          Length = 584

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 7/223 (3%)

Query: 12  AEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSP 71
           A+   A +  + N   + DV   VGQE  +  AHR +LA    +F  L            
Sbjct: 20  AQLILAQINKMRNGQHFCDVQLQVGQESFK--AHRLVLAASSPYFAALFTGGMKESSKDV 77

Query: 72  VVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
           V +  +    F  +L+F+YT  V +  ++V E++ AA    L E+  LC +F+   +D  
Sbjct: 78  VPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPL 137

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DE 190
                 Q +       L E    +I  H  E      FL L+   L+ +LRS++L + DE
Sbjct: 138 NCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEELSIEDE 197

Query: 191 AELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAEL 233
            ++  AA  W         + V EV  P+    R  LL P  L
Sbjct: 198 YQVFLAAMQWILKDLGKRRKHVVEVLDPI----RFPLLPPQRL 236


>gi|109150407 kelch-like 6 [Homo sapiens]
          Length = 621

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 9/194 (4%)

Query: 40  QEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYRH 99
           QE   HR +LA   N+F+ +   +        +++  V  E    +L++ YT+   + + 
Sbjct: 81  QEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAETMHTLLDYTYTSKALITKQ 140

Query: 100 SVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEAH 159
           +V  VL AA  +    + + C  F+ + L+ +     L++A T  L  L+++  ++I  +
Sbjct: 141 NVQRVLEAANLFQFLRMVDACASFLTEALNPENCVGILRLADTHSLDSLKKQVQSYIIQN 200

Query: 160 SQEALRTRGFLELSAAALLPLLRSDKLCV-DEAELVRAARSWARVGAAVLERPVAEVA-- 216
             + L +  FL+L    L  +L+SD L V +EA++     SW R       +P   +   
Sbjct: 201 FVQILNSEEFLDLPVDTLHHILKSDDLYVTEEAQVFETVMSWVR------HKPSERLCLL 254

Query: 217 APVVKELRLALLAP 230
             V++ +RL LL P
Sbjct: 255 PYVLENVRLPLLDP 268


>gi|223890235 intracisternal A particle-promoted polypeptide isoform
           2 [Homo sapiens]
          Length = 582

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 61/223 (27%), Positives = 94/223 (42%), Gaps = 7/223 (3%)

Query: 12  AEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSP 71
           A+   A +  + N   + DV   VGQE  +  AHR +LA    +F  L            
Sbjct: 20  AQLILAQINKMRNGQHFCDVQLQVGQESFK--AHRLVLAASSPYFAALFTGGMKESSKDV 77

Query: 72  VVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
           V +  +    F  +L+F+YT  V +  ++V E++ AA    L E+  LC +F+   +D  
Sbjct: 78  VPILGIEAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQIDPL 137

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DE 190
                 Q +       L E    +I  H  E      FL L+   L+ +LRS++L + DE
Sbjct: 138 NCIGIFQFSEQIACHDLLEFSENYIHVHFLEVHSGEEFLALTKDQLIKILRSEELSIEDE 197

Query: 191 AELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAEL 233
            ++  AA  W         + V EV  P+    R  LL P  L
Sbjct: 198 YQVFLAAMQWILKDLGKRRKHVVEVLDPI----RFPLLPPQRL 236


>gi|56117834 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|56117832 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|56117830 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|56117828 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|4507183 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|56117836 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)

Query: 19  LRSLVNNPRYSDVCF-VVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTV 77
           L  L  N R++D C  V GQE Q   AH+ +LA R   F  +   E      + V ++ V
Sbjct: 190 LGGLWENSRFTDCCLCVAGQEFQ---AHKAILAARSPVFSAMFEHEMEESKKNRVEINDV 246

Query: 78  PTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEAL 137
             E F  ++ F+YT           ++L AA +Y LE L+ +C   +   L V+   E L
Sbjct: 247 EPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEIL 306

Query: 138 QVAVTFGLGQLQERCVAFIEAHSQEALRTRGF 169
            +A      QL+ + V FI  H+ + L T G+
Sbjct: 307 ILADLHSADQLKTQAVDFINYHASDVLETSGW 338


>gi|45593142 kelch repeat and BTB (POZ) domain containing 5 [Homo
           sapiens]
          Length = 621

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 62/229 (27%), Positives = 101/229 (44%), Gaps = 8/229 (3%)

Query: 19  LRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVP 78
           L+ ++++ ++ D C V   ER E   HR +LA    +F+     EP       + L  V 
Sbjct: 23  LKDMLDHGKFLD-CVVRAGER-EFPCHRLVLAACSPYFRARFLAEPERA--GELHLEEVS 78

Query: 79  TEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQ 138
            +    VL +LYT+ + L   SV ++  AA  + +  +  +C+ F+ K L +       +
Sbjct: 79  PDVVAQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLSNCLAVFR 138

Query: 139 VAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVDEAELV-RAA 197
           + +     +L      FI AH     R   FL LSA  L+ ++ SD L V++ E V  A 
Sbjct: 139 LGLLLDCARLAVAARDFICAHFTLVARDADFLGLSADELIAIISSDGLNVEKEEAVFEAV 198

Query: 198 RSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLI 246
             WA  G A  +         V + +R  LL  A    LE +  + PL+
Sbjct: 199 MRWAGSGDAEAQAERQRALPTVFESVRCRLLPRA---FLESRVERHPLV 244


>gi|38327518 BTB and kelch domain containing 3 [Homo sapiens]
          Length = 612

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 52/249 (20%), Positives = 109/249 (43%), Gaps = 15/249 (6%)

Query: 12  AEPFSAALRSLVNNPRYSDVC--FVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVP 69
           +E     + S++ N R  +V   F +  + + +  HRC+LA   +FF+ +          
Sbjct: 31  SEDHGQKILSVLQNFREQNVFYDFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERDD 90

Query: 70  SPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLD 129
             V ++ + ++A  A L++ YT   K+   +V      +    +  L + C  F++K ++
Sbjct: 91  GSVTITNLSSKAVKAFLDYAYTGKTKITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSIN 150

Query: 130 VDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVD 189
           +    + L ++ ++G   L +  + F++ H     ++  FLE++   L   L SD+L V 
Sbjct: 151 LVNCLQLLSISDSYGSTSLFDHALHFVQHHFSLLFKSSDFLEMNFGVLQKCLESDELNVP 210

Query: 190 EAELV-RAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPV 248
           E E+V +   SW +      ++ +              L+    L  L E+  Q+ L   
Sbjct: 211 EEEMVLKVVLSWTKHNLESRQKYLPH------------LIEKVRLHQLSEETLQDCLFNE 258

Query: 249 EQIVEAWKC 257
           E ++++  C
Sbjct: 259 ESLLKSTNC 267


>gi|38327516 BTB and kelch domain containing 3 [Homo sapiens]
          Length = 612

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 52/249 (20%), Positives = 109/249 (43%), Gaps = 15/249 (6%)

Query: 12  AEPFSAALRSLVNNPRYSDVC--FVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVP 69
           +E     + S++ N R  +V   F +  + + +  HRC+LA   +FF+ +          
Sbjct: 31  SEDHGQKILSVLQNFREQNVFYDFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERDD 90

Query: 70  SPVVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLD 129
             V ++ + ++A  A L++ YT   K+   +V      +    +  L + C  F++K ++
Sbjct: 91  GSVTITNLSSKAVKAFLDYAYTGKTKITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSIN 150

Query: 130 VDLVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVD 189
           +    + L ++ ++G   L +  + F++ H     ++  FLE++   L   L SD+L V 
Sbjct: 151 LVNCLQLLSISDSYGSTSLFDHALHFVQHHFSLLFKSSDFLEMNFGVLQKCLESDELNVP 210

Query: 190 EAELV-RAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPV 248
           E E+V +   SW +      ++ +              L+    L  L E+  Q+ L   
Sbjct: 211 EEEMVLKVVLSWTKHNLESRQKYLPH------------LIEKVRLHQLSEETLQDCLFNE 258

Query: 249 EQIVEAWKC 257
           E ++++  C
Sbjct: 259 ESLLKSTNC 267


>gi|24432026 kelch-like [Homo sapiens]
          Length = 634

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 47/169 (27%), Positives = 82/169 (48%), Gaps = 3/169 (1%)

Query: 30  DVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFL 89
           DV  VV  E + + AHR LLA  C++F+ +            V++  V   A   +L F+
Sbjct: 51  DVVLVV--EGRHIEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFI 108

Query: 90  YTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQ 149
           YT+ ++L   +V E L AA +  + E+   C  F++  +D + + +  ++A  F L +L 
Sbjct: 109 YTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAELFDLSRLT 168

Query: 150 ERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCVD-EAELVRAA 197
           E+   +I  +     RT  + +L    +  LL S++L V  E E+   A
Sbjct: 169 EQLDTYILKNFVAFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGA 217


>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
          Length = 586

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 64/258 (24%), Positives = 113/258 (43%), Gaps = 19/258 (7%)

Query: 17  AALRSLVNNPRYS----DVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPV 72
           A    ++NN R      DV  +V QER+ + AHR +LA   +FF  +  T         V
Sbjct: 28  AGFMGVMNNMRKQKTLCDVILMV-QERK-IPAHRVVLAAASHFFNLMFTTNMLESKSFEV 85

Query: 73  VLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDL 132
            L     +    ++EF YT  + +  ++V  +L AA +Y +E ++++C+ F+ + +D   
Sbjct: 86  ELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASN 145

Query: 133 VCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DEA 191
                 +A      +L+     FI  H  E  +T  FL+L    +  LL  D L V  E 
Sbjct: 146 CLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAED 205

Query: 192 ELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIP---- 247
           ++  AA  W +      +  + ++ A V    R  L++    + L +  + EPLI     
Sbjct: 206 QVYDAAVRWLKYDEPNRQPFMVDILAKV----RFPLISK---NFLSKTVQAEPLIQDNPE 258

Query: 248 -VEQIVEAWKCHALRRGD 264
            ++ ++   + H L   D
Sbjct: 259 CLKMVISGMRYHLLSPED 276


>gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]
          Length = 564

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 60/241 (24%), Positives = 107/241 (44%), Gaps = 15/241 (6%)

Query: 30  DVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFL 89
           DV  +V QER+ + AHR +LA   +FF  +  T         V L     +    ++EF 
Sbjct: 23  DVILMV-QERK-IPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFA 80

Query: 90  YTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQ 149
           YT  + +  ++V  +L AA +Y +E ++++C+ F+ + +D         +A      +L+
Sbjct: 81  YTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELK 140

Query: 150 ERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DEAELVRAARSWARVGAAVL 208
                FI  H  E  +T  FL+L    +  LL  D L V  E ++  AA  W +      
Sbjct: 141 ATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNR 200

Query: 209 ERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIP-----VEQIVEAWKCHALRRG 263
           +  + ++ A V    R  L++    + L +  + EPLI      ++ ++   + H L   
Sbjct: 201 QPFMVDILAKV----RFPLISK---NFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPE 253

Query: 264 D 264
           D
Sbjct: 254 D 254


>gi|55770880 kelch-like 5 isoform 3 [Homo sapiens]
          Length = 709

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 57/251 (22%), Positives = 112/251 (44%), Gaps = 8/251 (3%)

Query: 12  AEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSP 71
           AE     + + + + +  DV  V G  R  + AHR +L+   ++F  +   +        
Sbjct: 157 AEQTFKKMENYLRHKQLCDVILVAGDRR--IPAHRLVLSSVSDYFAAMFTNDVREARQEE 214

Query: 72  VVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
           + +  V   +  +++++ YT  ++L   ++  +L+ A    L ++ E C +F++K L   
Sbjct: 215 IKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPS 274

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DE 190
                   A   G   L +    +   H  E +R + F+ L A+ +  LL SD + + +E
Sbjct: 275 NCLGIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNE 334

Query: 191 AELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQ 250
             ++ A  +W R       + ++++ A     +RL LLAP  L+ +E        I  ++
Sbjct: 335 ETILNALLTWVRHDLEQRRKDLSKLLA----YIRLPLLAPQFLADMENNVLFRDDIECQK 390

Query: 251 -IVEAWKCHAL 260
            I+EA K H L
Sbjct: 391 LIMEAMKYHLL 401


>gi|65289292 kelch-like 5 isoform 1 [Homo sapiens]
          Length = 755

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 57/251 (22%), Positives = 112/251 (44%), Gaps = 8/251 (3%)

Query: 12  AEPFSAALRSLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSP 71
           AE     + + + + +  DV  V G  R  + AHR +L+   ++F  +   +        
Sbjct: 203 AEQTFKKMENYLRHKQLCDVILVAGDRR--IPAHRLVLSSVSDYFAAMFTNDVREARQEE 260

Query: 72  VVLSTVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVD 131
           + +  V   +  +++++ YT  ++L   ++  +L+ A    L ++ E C +F++K L   
Sbjct: 261 IKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPS 320

Query: 132 LVCEALQVAVTFGLGQLQERCVAFIEAHSQEALRTRGFLELSAAALLPLLRSDKLCV-DE 190
                   A   G   L +    +   H  E +R + F+ L A+ +  LL SD + + +E
Sbjct: 321 NCLGIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNE 380

Query: 191 AELVRAARSWARVGAAVLERPVAEVAAPVVKELRLALLAPAELSALEEQNRQEPLIPVEQ 250
             ++ A  +W R       + ++++ A     +RL LLAP  L+ +E        I  ++
Sbjct: 381 ETILNALLTWVRHDLEQRRKDLSKLLA----YIRLPLLAPQFLADMENNVLFRDDIECQK 436

Query: 251 -IVEAWKCHAL 260
            I+EA K H L
Sbjct: 437 LIMEAMKYHLL 447


>gi|8922854 kelch-like 26 [Homo sapiens]
          Length = 615

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 54/196 (27%), Positives = 87/196 (44%), Gaps = 6/196 (3%)

Query: 39  RQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLYR 98
           R+   AH+ +LA   ++F+ +            + L  V       +++F Y+  V L  
Sbjct: 71  REAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDL 130

Query: 99  HSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIEA 158
             V +VL AAV   +  + ELC +F+   + V+      Q+A TF L  L+E   AF   
Sbjct: 131 DCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASLRESVDAFTFR 190

Query: 159 HSQEALRTRGFLELSAAALLPLLRSDKL-CVDEAELVRAARSWARVGAAVLERPVAEVAA 217
           H  +      FL L    L+  L+S++L    E +L RAA  W +   A   R     A+
Sbjct: 191 HFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRPR-----AS 245

Query: 218 PVVKELRLALLAPAEL 233
            V+  +R  L+  +EL
Sbjct: 246 HVLCHIRFPLMQSSEL 261


>gi|23397572 kelch-like 34 [Homo sapiens]
          Length = 644

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 5/170 (2%)

Query: 38  ERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVVLSTVPTEAFLAVLEFLYTNSVKLY 97
           E  E  AHR LLAC  ++F+ L  +         + L          +L+F+YT  + L 
Sbjct: 36  EGSEFPAHRSLLACSSDYFRALFKSHTQESRARVIHLHVPSAAGLQRLLDFIYTAWLSLS 95

Query: 98  RHSVLEVLTAAVEYGLEELRELCLQFVVKVLDVDLVCEALQVAVTFGLGQLQERCVAFIE 157
             +V + L AA    + E   LC +++ + L  +  C A  VA  FGL    +     I 
Sbjct: 96  MDTVEDTLEAASYLQVTEALGLCGRYLERQLAPENCCFAANVAARFGLAHTLDAAERCIV 155

Query: 158 AHSQEALR----TRGFLELSAAALLPLLRS-DKLCVDEAELVRAARSWAR 202
           +H QE L       G LEL+  +L  +L + D   V EA L+  A +W R
Sbjct: 156 SHLQELLARGAGPAGLLELNPTSLRAVLGAPDVARVPEARLLGLALAWLR 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,898,757
Number of Sequences: 37866
Number of extensions: 474562
Number of successful extensions: 1954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 1793
Number of HSP's gapped (non-prelim): 163
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.