Guide to the Human Genome
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Search of human proteins with 20986514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo ...   603   e-173
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ...   569   e-163
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s...   545   e-155
gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo ...   518   e-147
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]        456   e-129
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]        389   e-108
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]         375   e-104
gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alph...   287   7e-78
gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alph...   287   7e-78
gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta...   286   2e-77
gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta...   286   2e-77
gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta...   281   5e-76
gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta...   281   5e-76
gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo s...   275   5e-74
gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo ...   275   5e-74
gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo ...   275   5e-74
gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alph...   273   1e-73
gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha...   273   1e-73
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]         268   3e-72
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]         268   3e-72
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s...   265   3e-71
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s...   265   3e-71
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...   260   1e-69
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...   260   1e-69
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...   260   1e-69
gi|205277412 mitogen-activated protein kinase 9 isoform JNK2 gam...   254   8e-68
gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo ...   241   7e-64
gi|149408126 nemo like kinase [Homo sapiens]                          220   1e-57
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]        196   3e-50
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]          184   6e-47

>gi|20986514 mitogen-activated protein kinase 14 isoform 3 [Homo
           sapiens]
          Length = 297

 Score =  603 bits (1554), Expect = e-173
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
           MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
Sbjct: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60

Query: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
           SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
Sbjct: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120

Query: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
           KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
           GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240

Query: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI 297
           TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI
Sbjct: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI 297


>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
           sapiens]
          Length = 360

 Score =  569 bits (1467), Expect = e-163
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
           MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
Sbjct: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60

Query: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
           SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
Sbjct: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120

Query: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
           KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
           GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240

Query: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
           TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL
Sbjct: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280


>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
           sapiens]
          Length = 360

 Score =  545 bits (1404), Expect = e-155
 Identities = 266/280 (95%), Positives = 272/280 (97%)

Query: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
           MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
Sbjct: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60

Query: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
           SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
Sbjct: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120

Query: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
           KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
           GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI+QL+ I+RL G
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG 240

Query: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
           TP A L+ ++ S  ARNYIQSLTQMPKMNFANVFIGANPL
Sbjct: 241 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPL 280


>gi|20986516 mitogen-activated protein kinase 14 isoform 4 [Homo
           sapiens]
          Length = 307

 Score =  518 bits (1333), Expect = e-147
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
           MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
Sbjct: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60

Query: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
           SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
Sbjct: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120

Query: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
           KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
Sbjct: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
           GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240

Query: 241 TPGAELLKKISSES 254
           TPGAELLKKISSES
Sbjct: 241 TPGAELLKKISSES 254


>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
          Length = 364

 Score =  456 bits (1174), Expect = e-129
 Identities = 218/280 (77%), Positives = 249/280 (88%)

Query: 1   MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ 60
           MS  R  FYRQELNKT+WEVP+R Q L PVGSGAYGSVC+A+D +   +VAVKKLSRPFQ
Sbjct: 1   MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ 60

Query: 61  SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ 120
           S+IHA+RTYRELRLLKH+KHENVIGLLDVFTPA S+E+F++VYLVT LMGADLNNIVKCQ
Sbjct: 61  SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ 120

Query: 121 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT 180
            L+D+HVQFL+YQ+LRGLKYIHSA IIHRDLKPSN+AVNEDCEL+ILDFGLAR  D+EMT
Sbjct: 121 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT 180

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG 240
           GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELL G+ LFPG+D+IDQLK I+ +VG
Sbjct: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG 240

Query: 241 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
           TP  E+L KISSE AR YIQSL  MP+ + +++F GANPL
Sbjct: 241 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPL 280


>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
          Length = 367

 Score =  389 bits (998), Expect = e-108
 Identities = 179/276 (64%), Positives = 226/276 (81%)

Query: 5   RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIH 64
           R  FYRQE+ KT WEV   Y++L PVGSGAYG+VC+A D +TG +VA+KKL RPFQS + 
Sbjct: 8   RSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELF 67

Query: 65  AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTD 124
           AKR YRELRLLKHM+HENVIGLLDVFTP  +L++F D YLV   MG DL  ++K +KL +
Sbjct: 68  AKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGE 127

Query: 125 DHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVA 184
           D +QFL+YQ+L+GL+YIH+A IIHRDLKP NLAVNEDCELKILDFGLAR  D EMTGYV 
Sbjct: 128 DRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV 187

Query: 185 TRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGA 244
           TRWYRAPE++LNWM Y QTVDIWSVGCIMAE++TG+TLF G+DH+DQLK I+++ GTP A
Sbjct: 188 TRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPA 247

Query: 245 ELLKKISSESARNYIQSLTQMPKMNFANVFIGANPL 280
           E ++++ S+ A+NY++ L ++ K +FA++   A+PL
Sbjct: 248 EFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPL 283


>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
          Length = 365

 Score =  375 bits (963), Expect = e-104
 Identities = 176/272 (64%), Positives = 222/272 (81%), Gaps = 1/272 (0%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY+Q++NKT WE+P+ Y + + VGSGAYGSVC+A D ++G +VA+KKLSRPFQS I AKR
Sbjct: 9   FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKR 68

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLKHM+HENVIGLLDVFTPA SL  F D YLV   M  DL  I+  +  +++ +
Sbjct: 69  AYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGME-FSEEKI 127

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRW 187
           Q+L+YQ+L+GLKYIHSA ++HRDLKP NLAVNEDCELKILDFGLARH D EMTGYV TRW
Sbjct: 128 QYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRW 187

Query: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELL 247
           YRAPE++L+WMHYNQTVDIWSVGCIMAE+LTG+TLF G D++DQL  IL++ G PG E +
Sbjct: 188 YRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFV 247

Query: 248 KKISSESARNYIQSLTQMPKMNFANVFIGANP 279
           +K++ ++A++YIQSL Q P+ +F  +F  A+P
Sbjct: 248 QKLNDKAAKSYIQSLPQTPRKDFTQLFPRASP 279


>gi|21237739 mitogen-activated protein kinase 9 isoform JNK2 alpha1
           [Homo sapiens]
          Length = 382

 Score =  287 bits (735), Expect = 7e-78
 Identities = 147/269 (54%), Positives = 193/269 (71%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTDHIDQ   ++  +GTP AE
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAE 247

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  + P + F  +F
Sbjct: 248 FMKKL-QPTVRNYVENRPKYPGIKFEELF 275


>gi|21237736 mitogen-activated protein kinase 9 isoform JNK2 alpha2
           [Homo sapiens]
          Length = 424

 Score =  287 bits (735), Expect = 7e-78
 Identities = 147/269 (54%), Positives = 193/269 (71%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTDHIDQ   ++  +GTP AE
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAE 247

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  + P + F  +F
Sbjct: 248 FMKKL-QPTVRNYVENRPKYPGIKFEELF 275


>gi|21237745 mitogen-activated protein kinase 9 isoform JNK2 beta2
           [Homo sapiens]
          Length = 424

 Score =  286 bits (732), Expect = 2e-77
 Identities = 146/269 (54%), Positives = 194/269 (72%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIMAE++  + LFPG D+IDQ   ++  +GTP AE
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAE 247

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  + P + F  +F
Sbjct: 248 FMKKL-QPTVRNYVENRPKYPGIKFEELF 275


>gi|21237742 mitogen-activated protein kinase 9 isoform JNK2 beta1
           [Homo sapiens]
          Length = 382

 Score =  286 bits (732), Expect = 2e-77
 Identities = 146/269 (54%), Positives = 194/269 (72%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIMAE++  + LFPG D+IDQ   ++  +GTP AE
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAE 247

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  + P + F  +F
Sbjct: 248 FMKKL-QPTVRNYVENRPKYPGIKFEELF 275


>gi|20986521 mitogen-activated protein kinase 8 isoform JNK1 beta2
           [Homo sapiens]
          Length = 427

 Score =  281 bits (719), Expect = 5e-76
 Identities = 144/275 (52%), Positives = 192/275 (69%), Gaps = 5/275 (1%)

Query: 2   SQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQS 61
           S+    FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+
Sbjct: 4   SKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQN 63

Query: 62  IIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK 121
             HAKR YREL L+K + H+N+IGLL+VFTP +SLEEF DVY+V  LM A+L  +++  +
Sbjct: 64  QTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-ME 122

Query: 122 LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEM 179
           L  + + +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   M
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 182

Query: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLV 239
           T YV TR+YRAPE++L  M Y + VDIWSVGCIM E++ G  LFPGTDHIDQ   ++  +
Sbjct: 183 TPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQL 241

Query: 240 GTPGAELLKKISSESARNYIQSLTQMPKMNFANVF 274
           GTP  E +KK+   + R Y+++  +    +F  +F
Sbjct: 242 GTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLF 275


>gi|20986519 mitogen-activated protein kinase 8 isoform JNK1 beta1
           [Homo sapiens]
          Length = 384

 Score =  281 bits (719), Expect = 5e-76
 Identities = 144/275 (52%), Positives = 192/275 (69%), Gaps = 5/275 (1%)

Query: 2   SQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQS 61
           S+    FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+
Sbjct: 4   SKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQN 63

Query: 62  IIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK 121
             HAKR YREL L+K + H+N+IGLL+VFTP +SLEEF DVY+V  LM A+L  +++  +
Sbjct: 64  QTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-ME 122

Query: 122 LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEM 179
           L  + + +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   M
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 182

Query: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLV 239
           T YV TR+YRAPE++L  M Y + VDIWSVGCIM E++ G  LFPGTDHIDQ   ++  +
Sbjct: 183 TPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQL 241

Query: 240 GTPGAELLKKISSESARNYIQSLTQMPKMNFANVF 274
           GTP  E +KK+   + R Y+++  +    +F  +F
Sbjct: 242 GTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLF 275


>gi|4506081 mitogen-activated protein kinase 10 isoform 1 [Homo
           sapiens]
          Length = 422

 Score =  275 bits (702), Expect = 5e-74
 Identities = 140/269 (52%), Positives = 189/269 (70%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+  HAKR
Sbjct: 48  FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL L+K + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  +++  +L  + +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERM 166

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   MT YV T
Sbjct: 167 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVT 226

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIM E++  + LFPG D+IDQ   ++  +GTP  E
Sbjct: 227 RYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPE 285

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  +   + F  +F
Sbjct: 286 FMKKL-QPTVRNYVENRPKYAGLTFPKLF 313


>gi|20986510 mitogen-activated protein kinase 10 isoform 2 [Homo
           sapiens]
          Length = 464

 Score =  275 bits (702), Expect = 5e-74
 Identities = 140/269 (52%), Positives = 189/269 (70%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+  HAKR
Sbjct: 48  FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 107

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL L+K + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  +++  +L  + +
Sbjct: 108 AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERM 166

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   MT YV T
Sbjct: 167 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVT 226

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIM E++  + LFPG D+IDQ   ++  +GTP  E
Sbjct: 227 RYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPE 285

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  +   + F  +F
Sbjct: 286 FMKKL-QPTVRNYVENRPKYAGLTFPKLF 313


>gi|20986506 mitogen-activated protein kinase 10 isoform 3 [Homo
           sapiens]
          Length = 426

 Score =  275 bits (702), Expect = 5e-74
 Identities = 140/269 (52%), Positives = 189/269 (70%), Gaps = 5/269 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+  HAKR
Sbjct: 10  FYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL L+K + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  +++  +L  + +
Sbjct: 70  AYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
           R+YRAPE++L  M Y + VDIWSVGCIM E++  + LFPG D+IDQ   ++  +GTP  E
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPE 247

Query: 246 LLKKISSESARNYIQSLTQMPKMNFANVF 274
            +KK+   + RNY+++  +   + F  +F
Sbjct: 248 FMKKL-QPTVRNYVENRPKYAGLTFPKLF 275


>gi|20986523 mitogen-activated protein kinase 8 isoform JNK1 alpha2
           [Homo sapiens]
          Length = 427

 Score =  273 bits (699), Expect = 1e-73
 Identities = 140/275 (50%), Positives = 191/275 (69%), Gaps = 5/275 (1%)

Query: 2   SQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQS 61
           S+    FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+
Sbjct: 4   SKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQN 63

Query: 62  IIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK 121
             HAKR YREL L+K + H+N+IGLL+VFTP +SLEEF DVY+V  LM A+L  +++  +
Sbjct: 64  QTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-ME 122

Query: 122 LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEM 179
           L  + + +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   M
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 182

Query: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLV 239
           T YV TR+YRAPE++L  M Y + VD+WSVGCIM E++  + LFPG D+IDQ   ++  +
Sbjct: 183 TPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQL 241

Query: 240 GTPGAELLKKISSESARNYIQSLTQMPKMNFANVF 274
           GTP  E +KK+   + R Y+++  +    +F  +F
Sbjct: 242 GTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLF 275


>gi|4506095 mitogen-activated protein kinase 8 isoform JNK1 alpha1
           [Homo sapiens]
          Length = 384

 Score =  273 bits (699), Expect = 1e-73
 Identities = 140/275 (50%), Positives = 191/275 (69%), Gaps = 5/275 (1%)

Query: 2   SQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQS 61
           S+    FY  E+  + + V +RYQNL P+GSGA G VCAA+D      VA+KKLSRPFQ+
Sbjct: 4   SKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQN 63

Query: 62  IIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK 121
             HAKR YREL L+K + H+N+IGLL+VFTP +SLEEF DVY+V  LM A+L  +++  +
Sbjct: 64  QTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-ME 122

Query: 122 LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEM 179
           L  + + +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T   M
Sbjct: 123 LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMM 182

Query: 180 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLV 239
           T YV TR+YRAPE++L  M Y + VD+WSVGCIM E++  + LFPG D+IDQ   ++  +
Sbjct: 183 TPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQL 241

Query: 240 GTPGAELLKKISSESARNYIQSLTQMPKMNFANVF 274
           GTP  E +KK+   + R Y+++  +    +F  +F
Sbjct: 242 GTPCPEFMKKL-QPTVRTYVENRPKYAGYSFEKLF 275


>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  268 bits (686), Expect = 3e-72
 Identities = 138/284 (48%), Positives = 193/284 (67%), Gaps = 14/284 (4%)

Query: 17  IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLK 76
           +++V  RY NLS +G GAYG VC+A+D    +RVA+KK+S PF+   + +RT RE+++L 
Sbjct: 18  VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILL 76

Query: 77  HMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILR 136
             +HEN+IG+ D+   A ++E+  DVY+V  LM  DL  ++K Q L++DH+ + +YQILR
Sbjct: 77  RFRHENIIGINDIIR-APTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILR 135

Query: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRA 190
           GLKYIHSA+++HRDLKPSNL +N  C+LKI DFGLAR  D +      +T YVATRWYRA
Sbjct: 136 GLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRA 195

Query: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
           PEIMLN   Y +++DIWSVGCI+AE+L+ R +FPG  ++DQL  IL ++G+P  E L  I
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 255

Query: 251 SSESARNYIQSLTQMPKMNFANVFIGANPLG------KLTIYPH 288
            +  ARNY+ SL    K+ +  +F  A+          LT  PH
Sbjct: 256 INLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPH 299


>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  268 bits (686), Expect = 3e-72
 Identities = 138/284 (48%), Positives = 193/284 (67%), Gaps = 14/284 (4%)

Query: 17  IWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLK 76
           +++V  RY NLS +G GAYG VC+A+D    +RVA+KK+S PF+   + +RT RE+++L 
Sbjct: 18  VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILL 76

Query: 77  HMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILR 136
             +HEN+IG+ D+   A ++E+  DVY+V  LM  DL  ++K Q L++DH+ + +YQILR
Sbjct: 77  RFRHENIIGINDIIR-APTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILR 135

Query: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRA 190
           GLKYIHSA+++HRDLKPSNL +N  C+LKI DFGLAR  D +      +T YVATRWYRA
Sbjct: 136 GLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRA 195

Query: 191 PEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
           PEIMLN   Y +++DIWSVGCI+AE+L+ R +FPG  ++DQL  IL ++G+P  E L  I
Sbjct: 196 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 255

Query: 251 SSESARNYIQSLTQMPKMNFANVFIGANPLG------KLTIYPH 288
            +  ARNY+ SL    K+ +  +F  A+          LT  PH
Sbjct: 256 INLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPH 299


>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 357

 Score =  265 bits (678), Expect = 3e-71
 Identities = 135/263 (51%), Positives = 184/263 (69%), Gaps = 8/263 (3%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V  RY  L  +G GAYG V +A+D     RVA+KK+S PF+   + +RT RE+++L  
Sbjct: 36  FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
            +HENVIG+ D+   A +LE   DVY+V  LM  DL  ++K Q+L++DH+ + +YQILRG
Sbjct: 95  FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153

Query: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
           LKYIHSA+++HRDLKPSNL +N  C+LKI DFGLAR  D E      +T YVATRWYRAP
Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213

Query: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKIS 251
           EIMLN   Y +++DIWSVGCI+AE+L+ R +FPG  ++DQL  IL ++G+P  E L  I 
Sbjct: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273

Query: 252 SESARNYIQSLTQMPKMNFANVF 274
           +  ARNY+QSL    K+ +A +F
Sbjct: 274 NMKARNYLQSLPSKTKVAWAKLF 296


>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 379

 Score =  265 bits (678), Expect = 3e-71
 Identities = 135/263 (51%), Positives = 184/263 (69%), Gaps = 8/263 (3%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V  RY  L  +G GAYG V +A+D     RVA+KK+S PF+   + +RT RE+++L  
Sbjct: 36  FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
            +HENVIG+ D+   A +LE   DVY+V  LM  DL  ++K Q+L++DH+ + +YQILRG
Sbjct: 95  FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153

Query: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
           LKYIHSA+++HRDLKPSNL +N  C+LKI DFGLAR  D E      +T YVATRWYRAP
Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213

Query: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKIS 251
           EIMLN   Y +++DIWSVGCI+AE+L+ R +FPG  ++DQL  IL ++G+P  E L  I 
Sbjct: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273

Query: 252 SESARNYIQSLTQMPKMNFANVF 274
           +  ARNY+QSL    K+ +A +F
Sbjct: 274 NMKARNYLQSLPSKTKVAWAKLF 296


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  260 bits (664), Expect = 1e-69
 Identities = 129/269 (47%), Positives = 182/269 (67%), Gaps = 8/269 (2%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V + Y+ +  +G+GAYG V +A    TG +VA+KK+   F  + +AKRT REL++LKH
Sbjct: 49  FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
            KH+N+I + D+  P     EF  VY+V  LM +DL+ I+   Q LT +HV++ +YQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168

Query: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
           GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR            MT YVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228

Query: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
           APE+ML+   Y Q +D+WSVGCI  E+L  R LFPG +++ QL+LI+ ++GTP   +++ 
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288

Query: 250 ISSESARNYIQSLTQMPKMNFANVFIGAN 278
           + +E  R YIQSL     + +  V+ GA+
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGAD 317


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  260 bits (664), Expect = 1e-69
 Identities = 129/269 (47%), Positives = 182/269 (67%), Gaps = 8/269 (2%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V + Y+ +  +G+GAYG V +A    TG +VA+KK+   F  + +AKRT REL++LKH
Sbjct: 49  FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
            KH+N+I + D+  P     EF  VY+V  LM +DL+ I+   Q LT +HV++ +YQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168

Query: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
           GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR            MT YVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228

Query: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
           APE+ML+   Y Q +D+WSVGCI  E+L  R LFPG +++ QL+LI+ ++GTP   +++ 
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288

Query: 250 ISSESARNYIQSLTQMPKMNFANVFIGAN 278
           + +E  R YIQSL     + +  V+ GA+
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGAD 317


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score =  260 bits (664), Expect = 1e-69
 Identities = 129/269 (47%), Positives = 182/269 (67%), Gaps = 8/269 (2%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V + Y+ +  +G+GAYG V +A    TG +VA+KK+   F  + +AKRT REL++LKH
Sbjct: 49  FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV-KCQKLTDDHVQFLIYQILR 136
            KH+N+I + D+  P     EF  VY+V  LM +DL+ I+   Q LT +HV++ +YQ+LR
Sbjct: 109 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168

Query: 137 GLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-------MTGYVATRWYR 189
           GLKY+HSA +IHRDLKPSNL VNE+CELKI DFG+AR            MT YVATRWYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228

Query: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
           APE+ML+   Y Q +D+WSVGCI  E+L  R LFPG +++ QL+LI+ ++GTP   +++ 
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288

Query: 250 ISSESARNYIQSLTQMPKMNFANVFIGAN 278
           + +E  R YIQSL     + +  V+ GA+
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPGAD 317


>gi|205277412 mitogen-activated protein kinase 9 isoform JNK2 gamma
           [Homo sapiens]
          Length = 242

 Score =  254 bits (648), Expect = 8e-68
 Identities = 131/224 (58%), Positives = 165/224 (73%), Gaps = 4/224 (1%)

Query: 8   FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKR 67
           FY  ++  + + V +RYQ L P+GSGA G VCAAFDT  G+ VAVKKLSRPFQ+  HAKR
Sbjct: 10  FYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKR 69

Query: 68  TYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
            YREL LLK + H+N+I LL+VFTP ++LEEF DVYLV  LM A+L  ++   +L  + +
Sbjct: 70  AYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-MELDHERM 128

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH--TDDEMTGYVAT 185
            +L+YQ+L G+K++HSA IIHRDLKPSN+ V  DC LKILDFGLAR   T+  MT YV T
Sbjct: 129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVT 188

Query: 186 RWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHI 229
           R+YRAPE++L  M Y + VDIWSVGCIM EL+ G  +F GTD I
Sbjct: 189 RYYRAPEVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDRI 231


>gi|158138507 mitogen-activated protein kinase 3 isoform 3 [Homo
           sapiens]
          Length = 335

 Score =  241 bits (614), Expect = 7e-64
 Identities = 121/227 (53%), Positives = 162/227 (71%), Gaps = 8/227 (3%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKH 77
           ++V  RY  L  +G GAYG V +A+D     RVA+KK+S PF+   + +RT RE+++L  
Sbjct: 36  FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLR 94

Query: 78  MKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRG 137
            +HENVIG+ D+   A +LE   DVY+V  LM  DL  ++K Q+L++DH+ + +YQILRG
Sbjct: 95  FRHENVIGIRDILR-ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRG 153

Query: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE------MTGYVATRWYRAP 191
           LKYIHSA+++HRDLKPSNL +N  C+LKI DFGLAR  D E      +T YVATRWYRAP
Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213

Query: 192 EIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRL 238
           EIMLN   Y +++DIWSVGCI+AE+L+ R +FPG  ++DQL  IL L
Sbjct: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILAL 260


>gi|149408126 nemo like kinase [Homo sapiens]
          Length = 527

 Score =  220 bits (560), Expect = 1e-57
 Identities = 117/236 (49%), Positives = 159/236 (67%), Gaps = 7/236 (2%)

Query: 29  PVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLD 88
           P+G GA+G V +  D + G RVA+KK+   FQ+++  KR +REL++L   KH+NV+  LD
Sbjct: 143 PIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALD 202

Query: 89  VFTPARSLEEFNDVYLVTHLMGADLNNI-VKCQKLTDDHVQFLIYQILRGLKYIHSADII 147
           +  P   ++ F ++Y+VT LM +DL+ I V  Q L+ DHV+  +YQILRGLKY+HSA I+
Sbjct: 203 ILQPPH-IDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGIL 261

Query: 148 HRDLKPSNLAVNEDCELKILDFGLARHTD-DE---MTGYVATRWYRAPEIMLNWMHYNQT 203
           HRD+KP NL VN +C LKI DFGLAR  + DE   MT  V T++YRAPEI++   HY+  
Sbjct: 262 HRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNA 321

Query: 204 VDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYI 259
           +DIWSVGCI AELL  R LF     I QL LI  L+GTP  E + + + E A+ +I
Sbjct: 322 IDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAM-RTACEGAKAHI 376


>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
          Length = 544

 Score =  196 bits (497), Expect = 3e-50
 Identities = 107/258 (41%), Positives = 151/258 (58%), Gaps = 14/258 (5%)

Query: 20  VPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHM- 78
           +  RY     +G GAYG V  A D +TG  VA+KK+   F+    A+RT+RE+ LL+   
Sbjct: 9   IVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFG 68

Query: 79  KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDD-HVQFLIYQILRG 137
            H N+I LLDV       E   D+YLV   M  DLN +++   L  D HV+ + YQ+LR 
Sbjct: 69  DHPNIISLLDVIRA----ENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRA 124

Query: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHT--------DDEMTGYVATRWYR 189
            +++HS  ++HRD KPSN+ ++ +C +K+ DFGLAR          D  +T YVATRWYR
Sbjct: 125 TRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYR 184

Query: 190 APEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK 249
           APE++L+   Y   VD+WS+GCI+ E+L GR LFPGT  + QL+LIL  +  P  E L  
Sbjct: 185 APEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLA 244

Query: 250 ISSESARNYIQSLTQMPK 267
           + S    + +  L   P+
Sbjct: 245 LGSGCRASVLHQLGSRPR 262


>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
          Length = 721

 Score =  184 bits (468), Expect = 6e-47
 Identities = 97/239 (40%), Positives = 153/239 (64%), Gaps = 21/239 (8%)

Query: 18  WEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKK--LSRPFQSIIHAKRTYRELRLL 75
           +++  RY +L P+G G  G V +A D     RVA+KK  L+ P QS+ HA    RE++++
Sbjct: 14  FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDP-QSVKHA---LREIKII 69

Query: 76  KHMKHENVIGLLDVFTPARS--------LEEFNDVYLVTHLMGADLNNIVKCQKLTDDHV 127
           + + H+N++ + ++  P+ S        L E N VY+V   M  DL N+++   L ++H 
Sbjct: 70  RRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHA 129

Query: 128 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVN-EDCELKILDFGLARHTD------DEMT 180
           +  +YQ+LRGLKYIHSA+++HRDLKP+NL +N ED  LKI DFGLAR  D        ++
Sbjct: 130 RLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLS 189

Query: 181 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLV 239
             + T+WYR+P ++L+  +Y + +D+W+ GCI AE+LTG+TLF G   ++Q++LIL  +
Sbjct: 190 EGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESI 248


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,014,299
Number of Sequences: 37866
Number of extensions: 454637
Number of successful extensions: 2814
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 731
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 847
Number of HSP's gapped (non-prelim): 882
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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