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Search of human proteins with 209863032
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209863032 transient receptor potential cation channel,
subfamily C, member 4 isoform zeta [Homo sapiens]
(804 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209863032 transient receptor potential cation channel, subfam... 1616 0.0
gi|7706747 transient receptor potential cation channel, subfamil... 1377 0.0
gi|209863024 transient receptor potential cation channel, subfam... 1371 0.0
gi|209863026 transient receptor potential cation channel, subfam... 998 0.0
gi|209863030 transient receptor potential cation channel, subfam... 898 0.0
gi|6912736 transient receptor potential cation channel, subfamil... 783 0.0
gi|209863028 transient receptor potential cation channel, subfam... 736 0.0
gi|4507685 transient receptor potential cation channel, subfamil... 410 e-114
gi|9966865 transient receptor potential cation channel, subfamil... 347 2e-95
gi|5730102 transient receptor potential cation channel, subfamil... 330 4e-90
gi|194733735 transient receptor potential cation channel, subfam... 327 2e-89
gi|4507687 transient receptor potential cation channel, subfamil... 327 2e-89
gi|169216484 PREDICTED: similar to transient receptor potential ... 200 4e-51
gi|109689695 transient receptor potential cation channel, subfam... 95 3e-19
gi|94538366 transient receptor potential cation channel, subfami... 87 5e-17
gi|18921093 transient receptor potential cation channel, subfami... 84 5e-16
gi|148612863 transient receptor potential cation channel, subfam... 84 5e-16
gi|154091312 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091308 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091310 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091320 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091318 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091316 transient receptor potential cation channel, subfam... 80 6e-15
gi|154091314 transient receptor potential cation channel, subfam... 80 6e-15
gi|239754785 PREDICTED: similar to transient receptor potential ... 80 8e-15
gi|239749299 PREDICTED: similar to transient receptor potential ... 80 8e-15
gi|239743393 PREDICTED: hypothetical protein XP_002342847, parti... 80 8e-15
gi|239509090 PREDICTED: similar to transient receptor potential ... 80 8e-15
gi|4507689 transient receptor potential cation channel, subfamil... 79 2e-14
gi|11225266 transient receptor potential cation channel, subfami... 65 2e-10
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 1616 bits (4185), Expect = 0.0
Identities = 804/804 (100%), Positives = 804/804 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKS 180
PSGEKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKS
Sbjct: 121 PSGEKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKS 180
Query: 181 PLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGF 240
PLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGF
Sbjct: 181 PLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGF 240
Query: 241 IWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHP 300
IWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHP
Sbjct: 241 IWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHP 300
Query: 301 TLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANG 360
TLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANG
Sbjct: 301 TLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANG 360
Query: 361 LNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFT 420
LNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFT
Sbjct: 361 LNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFT 420
Query: 421 EFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTL 480
EFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTL
Sbjct: 421 EFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTL 480
Query: 481 PTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNL 540
PTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNL
Sbjct: 481 PTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNL 540
Query: 541 VKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSN 600
VKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSN
Sbjct: 541 VKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSN 600
Query: 601 SADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQ 660
SADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQ
Sbjct: 601 SADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQ 660
Query: 661 RKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLAS 720
RKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLAS
Sbjct: 661 RKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLAS 720
Query: 721 RGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEE 780
RGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEE
Sbjct: 721 RGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEE 780
Query: 781 DSSIDYDLNLPDTVTHEDYVTTRL 804
DSSIDYDLNLPDTVTHEDYVTTRL
Sbjct: 781 DSSIDYDLNLPDTVTHEDYVTTRL 804
>gi|7706747 transient receptor potential cation channel, subfamily
C, member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 1377 bits (3564), Expect = 0.0
Identities = 679/681 (99%), Positives = 681/681 (100%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG
Sbjct: 297 QKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 356
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG
Sbjct: 357 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 416
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV
Sbjct: 417 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 476
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ
Sbjct: 477 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 536
Query: 364 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 423
LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV
Sbjct: 537 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 596
Query: 424 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 483
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP
Sbjct: 597 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 656
Query: 484 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 543
FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR
Sbjct: 657 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 716
Query: 544 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 603
YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD
Sbjct: 717 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 776
Query: 604 SDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKV 663
SDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKV
Sbjct: 777 SDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKV 836
Query: 664 NFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGD 723
NFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGD
Sbjct: 837 NFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGD 896
Query: 724 LSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSS 783
LSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSS
Sbjct: 897 LSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSS 956
Query: 784 IDYDLNLPDTVTHEDYVTTRL 804
IDYDLNLPDTVTHEDYVTTRL
Sbjct: 957 IDYDLNLPDTVTHEDYVTTRL 977
Score = 247 bits (630), Expect = 4e-65
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 1371 bits (3548), Expect = 0.0
Identities = 679/686 (98%), Positives = 681/686 (99%), Gaps = 5/686 (0%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG
Sbjct: 297 QKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 356
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG
Sbjct: 357 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 416
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV
Sbjct: 417 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 476
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ
Sbjct: 477 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 536
Query: 364 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 423
LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV
Sbjct: 537 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 596
Query: 424 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 483
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP
Sbjct: 597 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 656
Query: 484 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIG-----RRAADNLRRHHQYQEVMR 538
FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIG RRAADNLRRHHQYQEVMR
Sbjct: 657 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGVRTQHRRAADNLRRHHQYQEVMR 716
Query: 539 NLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKES 598
NLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKES
Sbjct: 717 NLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKES 776
Query: 599 SNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPRE 658
SNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPRE
Sbjct: 777 SNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPRE 836
Query: 659 KQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGL 718
KQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGL
Sbjct: 837 KQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGL 896
Query: 719 ASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAK 778
ASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAK
Sbjct: 897 ASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAK 956
Query: 779 EEDSSIDYDLNLPDTVTHEDYVTTRL 804
EEDSSIDYDLNLPDTVTHEDYVTTRL
Sbjct: 957 EEDSSIDYDLNLPDTVTHEDYVTTRL 982
Score = 247 bits (630), Expect = 4e-65
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 998 bits (2581), Expect = 0.0
Identities = 486/488 (99%), Positives = 488/488 (100%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG
Sbjct: 297 QKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 356
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG
Sbjct: 357 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 416
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV
Sbjct: 417 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 476
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ
Sbjct: 477 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 536
Query: 364 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 423
LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV
Sbjct: 537 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 596
Query: 424 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 483
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP
Sbjct: 597 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 656
Query: 484 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 543
FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR
Sbjct: 657 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 716
Query: 544 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 603
YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD
Sbjct: 717 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 776
Query: 604 SDEKSDSE 611
SDEKSDSE
Sbjct: 777 SDEKSDSE 784
Score = 247 bits (630), Expect = 4e-65
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
Score = 222 bits (566), Expect = 9e-58
Identities = 111/126 (88%), Positives = 118/126 (93%)
Query: 679 SKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH 738
SK+++ ++++ EEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH
Sbjct: 768 SKESSNSADSDEKSDSEEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH 827
Query: 739 RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED 798
RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED
Sbjct: 828 RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED 887
Query: 799 YVTTRL 804
YVTTRL
Sbjct: 888 YVTTRL 893
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 898 bits (2321), Expect = 0.0
Identities = 438/464 (94%), Positives = 446/464 (96%), Gaps = 3/464 (0%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG
Sbjct: 297 QKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 356
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG
Sbjct: 357 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 416
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV
Sbjct: 417 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 476
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ
Sbjct: 477 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 536
Query: 364 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 423
LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV
Sbjct: 537 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 596
Query: 424 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 483
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP
Sbjct: 597 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 656
Query: 484 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 543
FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR
Sbjct: 657 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 716
Query: 544 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS 587
YVAAMIRDAKTEE ++ L+++I + E GL LS
Sbjct: 717 YVAAMIRDAKTEEVARQQAAGPLERNI---QLESRGLASRGDLS 757
Score = 247 bits (630), Expect = 4e-65
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
Score = 219 bits (559), Expect = 6e-57
Identities = 109/110 (99%), Positives = 110/110 (100%)
Query: 695 SEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRV 754
+EEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRV
Sbjct: 727 TEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRV 786
Query: 755 CPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL 804
CPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL
Sbjct: 787 CPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL 836
>gi|6912736 transient receptor potential cation channel, subfamily
C, member 5 [Homo sapiens]
Length = 973
Score = 783 bits (2022), Expect = 0.0
Identities = 417/689 (60%), Positives = 492/689 (71%), Gaps = 47/689 (6%)
Query: 75 LIAIENE-NLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGE--------- 124
L +ENE E EL ++ D L A +E++LNH+ E
Sbjct: 230 LSKVENEFKAEYEELSQQCKLFAKDLLDQARSSR---ELEIILNHRDDHSEELDPQKYHD 286
Query: 125 ------------KQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSV 172
K+FVAQPNCQQLLA+ WYD FPGWRR+HW VK++TC IG LFP+ S+
Sbjct: 287 LAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSI 346
Query: 173 CYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWM 232
YLI+P+S LGLFI+KPFIKFICHTASYLTFLF+LLLASQHI R+DL+ QGPPPT+VEWM
Sbjct: 347 AYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWM 406
Query: 233 ILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPR 292
ILPWVLGFIWGEIK+MWDGG +YIHDWWNLMDF MNSLYLATISLKIVA+VKY+ PR
Sbjct: 407 ILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPR 466
Query: 293 ESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCL 352
E W+MWHPTL+AEALFAI+NI SSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCL
Sbjct: 467 EEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCL 526
Query: 353 VLLAFANGLNQLYFYYEETKGL----TCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL 408
VLLAFANGLNQLYFYY ET+ + CKGIRCEKQNNAFSTLFETLQSLFWS+FGL+NL
Sbjct: 527 VLLAFANGLNQLYFYY-ETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNL 585
Query: 409 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 468
YVTNVKA+HEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK
Sbjct: 586 YVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 645
Query: 469 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKK---MRRKPESFGTIGRRAAD 525
LWMSYF+EGGTLP PFN+IPSPKS YL W C K+ RR+ + + R AD
Sbjct: 646 LWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNAD 705
Query: 526 NLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSK 585
+L ++ YQEV+RNLVKRYVAAMIR++KT EGLTEENFKELKQDISSFR+EVL LL K
Sbjct: 706 SLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRK 765
Query: 586 LSTIQSANASKESSNSADSDEKSDSEGNSKDKKK--NFSLFDLTTLIHPRSAAIASERHN 643
+ S S+ + D+ +D G ++ K K +F+L H R +
Sbjct: 766 ----HPRSFSTSSTELSQRDDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSS 821
Query: 644 ISNGSALVVQEPPREKQRKVNFV-TDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQ 702
+ G + E K +F+ +K GL + + +E ++ ++++S+ + +Q
Sbjct: 822 GAQGKS------KAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQH 875
Query: 703 AAGPLERNIQLESRGLASRGDLSIPGLSE 731
R Q+E +G A S LSE
Sbjct: 876 CMWQDIRYSQME-KGKAEACSQSEINLSE 903
Score = 196 bits (499), Expect = 6e-50
Identities = 96/126 (76%), Positives = 118/126 (93%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQ YYK+ +PYRDRIPL+IVRAE+ELS EKA+LNAVEKGDYA+VK++L+EAEIY+
Sbjct: 1 MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYN 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
+NINC+DPLGR+ALLIAIENENLE++ELLL+ +VYVGDALL+AIRKEVVGAVELLL++++
Sbjct: 61 VNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRR 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 736 bits (1900), Expect = 0.0
Identities = 385/488 (78%), Positives = 398/488 (81%), Gaps = 65/488 (13%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG
Sbjct: 297 QKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 356
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG
Sbjct: 357 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 416
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV
Sbjct: 417 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 476
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ
Sbjct: 477 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 536
Query: 364 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFV 423
LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFG
Sbjct: 537 LYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFG------------------- 577
Query: 424 GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTP 483
L+N+ + + A H E+ G T+
Sbjct: 578 ---------------LINLYVTNVK------AQHEFTEFV-------------GATMFGT 603
Query: 484 FNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKR 543
+NVI SL L+ + + S+ I RRAADNLRRHHQYQEVMRNLVKR
Sbjct: 604 YNVI----SLVVLLNML--------IAMMNNSYQLIARRAADNLRRHHQYQEVMRNLVKR 651
Query: 544 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 603
YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD
Sbjct: 652 YVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSAD 711
Query: 604 SDEKSDSE 611
SDEKSDSE
Sbjct: 712 SDEKSDSE 719
Score = 247 bits (630), Expect = 4e-65
Identities = 126/126 (100%), Positives = 126/126 (100%)
Query: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK
Sbjct: 61 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
Query: 121 PSGEKQ 126
PSGEKQ
Sbjct: 121 PSGEKQ 126
Score = 222 bits (566), Expect = 9e-58
Identities = 111/126 (88%), Positives = 118/126 (93%)
Query: 679 SKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH 738
SK+++ ++++ EEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH
Sbjct: 703 SKESSNSADSDEKSDSEEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDH 762
Query: 739 RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED 798
RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED
Sbjct: 763 RERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHED 822
Query: 799 YVTTRL 804
YVTTRL
Sbjct: 823 YVTTRL 828
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 410 bits (1053), Expect = e-114
Identities = 217/480 (45%), Positives = 306/480 (63%), Gaps = 14/480 (2%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
+K+FV+Q NCQQ L + W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G
Sbjct: 284 QKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFG 343
Query: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
I PF+KFI H ASY TFL LL L S + N GP ++++++ W++G IW
Sbjct: 344 RIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWS 403
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
+IK++W GL+D++ + N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLV
Sbjct: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
Query: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
AE LFA AN+ S LRL ++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL Q
Sbjct: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
Query: 364 LYFY-YEETKGLTCKGIRCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEF 419
LY Y + C GI CE+Q N+ F + T +LFW IF L + ++VT E
Sbjct: 524 LYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEEL 583
Query: 420 TEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGT 479
FVGA + GTYNV+ ++VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ T
Sbjct: 584 QSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCT 643
Query: 480 LPTPFNVIPSPKSLWYLI----KWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQE 535
LP PFN+IPSPK++ Y+I KWI +H K K++R+ ++ +R YQ+
Sbjct: 644 LPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQ----NSLKEWRNLKQKRDENYQK 699
Query: 536 VMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLL--RGSKLSTIQSAN 593
VM LV RY+ +M + ++ + T EN EL+QD+S FR E+ LL R SK + N
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
Score = 66.2 bits (160), Expect = 1e-10
Identities = 37/73 (50%), Positives = 51/73 (69%), Gaps = 3/73 (4%)
Query: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
Query: 80 NENLELIELLLSF 92
NENL++++LLL +
Sbjct: 94 NENLDILQLLLDY 106
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 347 bits (891), Expect = 2e-95
Identities = 202/519 (38%), Positives = 293/519 (56%), Gaps = 79/519 (15%)
Query: 125 KQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGL 184
K+FVA PNCQQ L + WY+ G R++ AVK + F + + P ++ Y IAP S LG
Sbjct: 320 KKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGR 379
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTI---------------- 228
+R PF+KF+ H S+ FL LL++ + DR + + P T
Sbjct: 380 TLRSPFMKFVAHAVSFTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFS 437
Query: 229 -VEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS 287
E +I+ WVLG IW E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 438 WTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKAT 497
Query: 288 ------------------ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLIS 321
+L P R+ W P +++E L+AIA + S R+
Sbjct: 498 EAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAY 557
Query: 322 LFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRC 381
+ AN GPLQISLGR + DI KF+ I+ +V +AF G+ LY YY R
Sbjct: 558 ILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RG 606
Query: 382 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 441
K N AF+T+ E+ ++LFWSIFGL + +K H+F E +G ++G YNV +VVLLN
Sbjct: 607 AKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLN 666
Query: 442 MLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IK 498
MLIAM+NNSYQ I + AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK
Sbjct: 667 MLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIK 726
Query: 499 WIWTHLCKKKMR-------------RKPESFGTIGRRAADNLRRHH------QYQEVMRN 539
LCK K + + ++ G R ++NL ++ +YQ++M+
Sbjct: 727 MCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKR 786
Query: 540 LVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVL 578
L+KRYV D + +E + E KE+KQDISS R+E+L
Sbjct: 787 LIKRYVLKAQVDRENDE-VNEGELKEIKQDISSLRYELL 824
Score = 75.1 bits (183), Expect = 2e-13
Identities = 46/118 (38%), Positives = 70/118 (59%), Gaps = 5/118 (4%)
Query: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
Query: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWY 142
ELLL VGDALL AI K V VE +LNH + ++ P Q+L +Y
Sbjct: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFY 152
>gi|5730102 transient receptor potential cation channel, subfamily
C, member 6 [Homo sapiens]
Length = 931
Score = 330 bits (845), Expect = 4e-90
Identities = 217/636 (34%), Positives = 328/636 (51%), Gaps = 115/636 (18%)
Query: 32 SEKAYLNAVEKGDYASVKKSLEEA--EIYFKININCID-PLGRTALLIAIENENLELIEL 88
SE + A+E + +V ++E+ Y K+++ C D +G L N E +E
Sbjct: 290 SEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLC-----RNTEEVEA 344
Query: 89 LLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWYDEFPGW 148
+L+ +V + H + + ++L + ++ K+FVA PNCQQ L S WY+ G
Sbjct: 345 ILNGDVETLQSGDHG--RPNLSRLKLAIKYEV----KKFVAHPNCQQQLLSIWYENLSGL 398
Query: 149 RRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLL 208
R++ AVK + + + P ++ Y AP S +G +R PF+KF+ H AS+ FL LL+
Sbjct: 399 RQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLV 458
Query: 209 LASQHIDRSDLNRQGPPPTIVE--------------WM---ILPWVLGFIWGEIKQMWDG 251
+ + DR + + P T + WM I+ WV+G IW E K++W
Sbjct: 459 MNAA--DRFEGTKLLPNETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQ 516
Query: 252 GLQDYIHDWWNLMDFVMNSLYLATISLKIVAF---------------------------V 284
G ++Y+ + WN++DF M +++ A+ + +AF V
Sbjct: 517 GPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNV 576
Query: 285 KYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDIL 344
KY L R WD P +++E L+AIA + S R+ + AN GPLQISLGR + DI
Sbjct: 577 KYYNL-ARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIF 635
Query: 345 KFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFG 404
KF+ I+ +V +AF G+ LY YY K QN AF+T+ E+ ++LFW+IFG
Sbjct: 636 KFMVIFIMVFVAFMIGMFNLYSYYIGAK-----------QNEAFTTVEESFKTLFWAIFG 684
Query: 405 LINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKF 464
L + + H+F E +G ++G YNV ++VLLNMLIAM+N+S+Q I D AD+EWKF
Sbjct: 685 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKF 744
Query: 465 ARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLI----KWIW-------------THLCKK 507
AR KLW SYFEEG TLP PFN++PSPKSL+YL+ KWI + K
Sbjct: 745 ARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKGFQEDAEMNKI 804
Query: 508 KMRRKPESFGT-------------IGRRAADNLRRH------------HQYQEVMRNLVK 542
+K G+ +G ++R QYQ++M+ L+K
Sbjct: 805 NEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIK 864
Query: 543 RYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVL 578
RYV D +++E + E KE+KQDISS R+E+L
Sbjct: 865 RYVLQAQIDKESDE-VNEGELKEIKQDISSLRYELL 899
Score = 74.7 bits (182), Expect = 3e-13
Identities = 46/118 (38%), Positives = 68/118 (57%), Gaps = 5/118 (4%)
Query: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
+ LS E+ +L+A E G+ V+K LEE +N+NC+D +G+ AL +A+ NE+LE+
Sbjct: 93 TSLSIEEERFLDAAEYGNIPVVRKMLEECH---SLNVNCVDYMGQNALQLAVANEHLEIT 149
Query: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWY 142
ELLL VGDALL AI K V VE +L+H + K+ P+ +L +Y
Sbjct: 150 ELLLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFY 207
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 327 bits (839), Expect = 2e-89
Identities = 209/609 (34%), Positives = 323/609 (53%), Gaps = 82/609 (13%)
Query: 32 SEKAYLNAVEKGDYASVKKSLEEA--EIYFKININCIDPLGRTALLIAIENENLELIELL 89
SE L A+E + + ++E+ Y K+++ C D + L E +E +
Sbjct: 304 SEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEE----VEAI 359
Query: 90 LSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWYDEFPGWR 149
L+ ++ + L K + V+L + ++ K+FVA PNCQQ L + WY+ G R
Sbjct: 360 LNGDLESAEPLEVHRHKASLSRVKLAIKYEV----KKFVAHPNCQQQLLTIWYENLSGLR 415
Query: 150 RRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLL 209
+ A+K + ++ L P ++ Y IAP S LG +R PF+KF+ H AS++ FL LL+
Sbjct: 416 EQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVF 475
Query: 210 ASQ----------HIDRSDLNRQ-----GPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQ 254
+ +I +D +Q T E +I+ WVLG +W E K++W G +
Sbjct: 476 NASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPR 535
Query: 255 DYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS------------------ALNP----- 291
+YI WN++DF M S+++A + + +AF++ + L P
Sbjct: 536 EYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYF 595
Query: 292 ---RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLF 348
R+ W P +++E L+AIA + S R+ + AN GPLQISLGR + DI KF+
Sbjct: 596 TYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMV 655
Query: 349 IYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL 408
++ +V AF G+ LY YY K N AF+T+ E+ ++LFWSIFGL +
Sbjct: 656 LFIMVFFAFMIGMFILYSYYLGAK-----------VNAAFTTVEESFKTLFWSIFGLSEV 704
Query: 409 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 468
+K H+F E +G ++G YNV +VVLLNMLIAM+N+SYQ I D +D+EWKFAR+K
Sbjct: 705 TSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSK 764
Query: 469 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADN- 526
LW+SYF++G TLP PF+++PSPKS Y I I C+++ +K G ++ N
Sbjct: 765 LWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNL 824
Query: 527 -----------------LRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQD 569
L + +YQ++M+ L+KRYV D + +E + E KE+KQD
Sbjct: 825 FTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDE-VNEGELKEIKQD 883
Query: 570 ISSFRFEVL 578
ISS R+E+L
Sbjct: 884 ISSLRYELL 892
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/118 (38%), Positives = 70/118 (59%), Gaps = 5/118 (4%)
Query: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
+ L+ E+ +L+A E G+ V+K LEE++ +N+NC+D +G+ AL +A+ NE+LE+
Sbjct: 107 TSLTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVT 163
Query: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWY 142
ELLL +GDALL AI K V VE +LNH + K+ P Q+L +Y
Sbjct: 164 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFY 221
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 327 bits (839), Expect = 2e-89
Identities = 209/609 (34%), Positives = 323/609 (53%), Gaps = 82/609 (13%)
Query: 32 SEKAYLNAVEKGDYASVKKSLEEA--EIYFKININCIDPLGRTALLIAIENENLELIELL 89
SE L A+E + + ++E+ Y K+++ C D + L E +E +
Sbjct: 231 SEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEE----VEAI 286
Query: 90 LSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWYDEFPGWR 149
L+ ++ + L K + V+L + ++ K+FVA PNCQQ L + WY+ G R
Sbjct: 287 LNGDLESAEPLEVHRHKASLSRVKLAIKYEV----KKFVAHPNCQQQLLTIWYENLSGLR 342
Query: 150 RRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLL 209
+ A+K + ++ L P ++ Y IAP S LG +R PF+KF+ H AS++ FL LL+
Sbjct: 343 EQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVF 402
Query: 210 ASQ----------HIDRSDLNRQ-----GPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQ 254
+ +I +D +Q T E +I+ WVLG +W E K++W G +
Sbjct: 403 NASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPR 462
Query: 255 DYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS------------------ALNP----- 291
+YI WN++DF M S+++A + + +AF++ + L P
Sbjct: 463 EYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYF 522
Query: 292 ---RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLF 348
R+ W P +++E L+AIA + S R+ + AN GPLQISLGR + DI KF+
Sbjct: 523 TYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMV 582
Query: 349 IYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL 408
++ +V AF G+ LY YY K N AF+T+ E+ ++LFWSIFGL +
Sbjct: 583 LFIMVFFAFMIGMFILYSYYLGAK-----------VNAAFTTVEESFKTLFWSIFGLSEV 631
Query: 409 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 468
+K H+F E +G ++G YNV +VVLLNMLIAM+N+SYQ I D +D+EWKFAR+K
Sbjct: 632 TSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSK 691
Query: 469 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADN- 526
LW+SYF++G TLP PF+++PSPKS Y I I C+++ +K G ++ N
Sbjct: 692 LWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNL 751
Query: 527 -----------------LRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQD 569
L + +YQ++M+ L+KRYV D + +E + E KE+KQD
Sbjct: 752 FTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDE-VNEGELKEIKQD 810
Query: 570 ISSFRFEVL 578
ISS R+E+L
Sbjct: 811 ISSLRYELL 819
Score = 76.6 bits (187), Expect = 8e-14
Identities = 46/118 (38%), Positives = 70/118 (59%), Gaps = 5/118 (4%)
Query: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
+ L+ E+ +L+A E G+ V+K LEE++ +N+NC+D +G+ AL +A+ NE+LE+
Sbjct: 34 TSLTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVT 90
Query: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWY 142
ELLL +GDALL AI K V VE +LNH + K+ P Q+L +Y
Sbjct: 91 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFY 148
>gi|169216484 PREDICTED: similar to transient receptor potential
channel subfamily C member 6 [Homo sapiens]
Length = 304
Score = 200 bits (509), Expect = 4e-51
Identities = 110/286 (38%), Positives = 160/286 (55%), Gaps = 39/286 (13%)
Query: 239 GFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF--------------- 283
G IW E K++W G ++Y+ + WN++DF M ++ A+ + AF
Sbjct: 17 GMIWAECKEIWTQGPKEYLFELWNMLDFGMLAILSASFIARFRAFWHASKAQSITDASDT 76
Query: 284 ------------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGP 331
VKY +L RE WD P +V+E L A+A + S + + AN GP
Sbjct: 77 LKDLTKVTLGDNVKYYSLARRE-WDPSDPRMVSEGLCAVAVVLSFSGIACILPANESFGP 135
Query: 332 LQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTL 391
LQ+SLG + DI +F+ I+ +V +AF G+ LY YY + K QN AF+T+
Sbjct: 136 LQMSLGGAVKDIFRFMLIFIMVFVAFMIGMFNLYSYYIDVK-----------QNEAFTTV 184
Query: 392 FETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSY 451
E+ ++LFW+ F L + + H+F E +G ++G Y+V ++VLLNMLIAM+N+S
Sbjct: 185 EESFKTLFWATFVLSAVKSVVINYSHKFIENIGYVLYGVYDVTMVIVLLNMLIAMINSSL 244
Query: 452 QLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLI 497
Q I D AD+EWKFAR KLW S F EG LP PFN++P P SL+ L+
Sbjct: 245 QEIEDDADVEWKFARAKLWFSCFGEGRALPVPFNLVPGPGSLFCLL 290
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 94.7 bits (234), Expect = 3e-19
Identities = 93/403 (23%), Positives = 168/403 (41%), Gaps = 49/403 (12%)
Query: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
++ F+AQP Q L+ +WY E ++W K++ C I P+ ++ K P+
Sbjct: 665 DQHFIAQPGVQNFLSKQWYGEISR-DTKNW--KIILCLFI---IPLVGCGFVSFRKKPVD 718
Query: 184 ----------LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMI 233
F PF+ F + Y+ FL L ++ D + PP +V + +
Sbjct: 719 KHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFA----YVLLMDFHSVPHPPELVLYSL 774
Query: 234 LPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRE 293
V E++Q + G+ +Y D WN+MD + ++A I ++ + K S + R
Sbjct: 775 ---VFVLFCDEVRQWYVNGV-NYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGR- 829
Query: 294 SWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLV 353
+F + I +LRLI +FT + +LGP I L RML+D+ FLF++ +
Sbjct: 830 ------------VIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVW 877
Query: 354 LLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAF--------STLFETLQSLFWSIFGL 405
++AF + E+ + + E F T ++ F
Sbjct: 878 MVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNESK 937
Query: 406 INLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFA 465
+ F E++ + Y + + ++L+N+L+AM + + ++ D WKF
Sbjct: 938 PLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQ 997
Query: 466 RTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKK 508
R L Y +P PF V + ++K + CK+K
Sbjct: 998 RYFLVQEYCSR-LNIPFPFIVF---AYFYMVVKKCFKCCCKEK 1036
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 87.4 bits (215), Expect = 5e-17
Identities = 81/382 (21%), Positives = 173/382 (45%), Gaps = 75/382 (19%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T SYL +L L L R P++ EW+++ +++ +
Sbjct: 823 FYNAPIVKFWFYTISYLGYLLLFNYVI-------LVRMDGWPSLQEWIVISYIVSLALEK 875
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYL--ATISLKIVAFVKYSALNPRESW 295
I++ M + G ++ ++ ++WN+ D V S ++ A + L+ ++ Y +
Sbjct: 876 IREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRV------ 929
Query: 296 DMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLL 355
++ + IF +R++ +F N +LGP + +G+M++D+L F+ I +VL+
Sbjct: 930 -----------IYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLM 978
Query: 356 AFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFG-----LINLYV 410
+F G+ + I ++ ++ +W I+G I+LY
Sbjct: 979 SF---------------GVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYA 1023
Query: 411 TNVK---AQHEFTE------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIA 455
+ ++ + E ++ + Y +++ ++L+N+LIA+ NN++ +
Sbjct: 1024 MEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVK 1083
Query: 456 DHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMR--RKP 513
++ WKF R +L M+ F + LP P ++ S Y+I + C+KK ++
Sbjct: 1084 SISNQVWKFQRYQLIMT-FHDRPVLPPPMIIL----SHIYIIIMRLSGRCRKKREGDQEE 1138
Query: 514 ESFGTIGRRAADNLRRHHQYQE 535
G + + L+R H+++E
Sbjct: 1139 RDRGLKLFLSDEELKRLHEFEE 1160
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 84.0 bits (206), Expect = 5e-16
Identities = 92/434 (21%), Positives = 178/434 (41%), Gaps = 75/434 (17%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +YL FL L L P P++ EW++ ++
Sbjct: 834 FYSAPIVKFWFYTMAYLAFLMLFTYTV-------LVEMQPQPSVQEWLVSIYIFTNAIEV 886
Query: 245 IKQM-------WDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
++++ + ++ +I ++WNL + V L+ A L+ W
Sbjct: 887 VREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGFVLR---------------WGD 931
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ I IF RL+ F N H GP + +M ++ + I +VLL+F
Sbjct: 932 PPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLSF 991
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLI---NLYVTNVK 414
G+ K I K+ ++S + + +W I+G + + V + +
Sbjct: 992 ---------------GVARKAILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQ 1036
Query: 415 AQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYF 474
F+ + Y + ++++N+LIA NN Y + ++ WK+ R + M+Y
Sbjct: 1037 PSCPPGSFLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTYH 1096
Query: 475 EEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRR---AADNLRRHH 531
E+ P+ +P P L + + LC + E G +G + + ++L++ H
Sbjct: 1097 EK------PW--LPPPLILLSHVGLLLRRLCCHRAPHDQEE-GDVGLKLYLSKEDLKKLH 1147
Query: 532 QYQEVMRNLVKRYVAAMIRDAK---------TEEGLTEENF--KELKQDISSFRFEVLGL 580
++E V++Y + D T E +TE F KE+ + +S + +L L
Sbjct: 1148 DFEE---QCVEKYFHEKMEDVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSL 1204
Query: 581 LRGSKLSTIQSANA 594
S++ +Q +A
Sbjct: 1205 --DSQVGHLQDLSA 1216
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 84.0 bits (206), Expect = 5e-16
Identities = 85/370 (22%), Positives = 160/370 (43%), Gaps = 61/370 (16%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +YL FL L L + P++ EW+++ ++ + +
Sbjct: 848 FYHAPIVKFWFNTLAYLGFLMLYTFVV-------LVQMEQLPSVQEWIVIAYIFTYAIEK 900
Query: 245 IKQMW---DGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSAL-NPRESWDMWHP 300
+++++ G + I W++ D+ S +A IS I +++ A N ++D H
Sbjct: 901 VREIFMSEAGKVNQKIKVWFS--DYFNISDTIAIISFFIGFGLRFGAKWNFANAYDN-HV 957
Query: 301 TLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANG 360
+ ++ + IF +RL+ N GP + +G+M+ ++ + I LVLL+F
Sbjct: 958 FVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVP 1017
Query: 361 LNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHE-- 418
+ + +E K I +F +W IFG + Y +V A
Sbjct: 1018 RKAILYPHEAPSWTLAKDI-----------VFHP----YWMIFGEVYAYEIDVCANDSVI 1062
Query: 419 ---------FTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKL 469
T F+ A Y + ++++N+LIA NN Y + ++I WK+ R
Sbjct: 1063 PQICGPGTWLTPFLQAV----YLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHF 1118
Query: 470 WMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRK----PESFGTIGRRAAD 525
M+Y E+ LP P ++ SL+ I CK++ + K P+ F T +
Sbjct: 1119 IMAYHEK-PVLPPPLIILSHIVSLFCCI-------CKRRKKDKTSDGPKLFLT-----EE 1165
Query: 526 NLRRHHQYQE 535
+ ++ H ++E
Sbjct: 1166 DQKKLHDFEE 1175
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 724 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 776
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 777 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 826
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 827 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 881
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 882 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 926
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 927 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 986
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 987 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1038
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1039 KLFITDDELKKVHDFEE 1055
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 737 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 789
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 790 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 839
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 840 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 894
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 895 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 939
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 940 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 999
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 1000 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1051
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1052 KLFITDDELKKVHDFEE 1068
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 727 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 779
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 780 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 829
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 830 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 884
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 885 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 929
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 930 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 989
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 990 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1041
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1042 KLFITDDELKKVHDFEE 1058
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 712 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 764
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 765 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 814
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 815 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 869
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 870 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 914
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 915 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 974
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 975 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1026
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1027 KLFITDDELKKVHDFEE 1043
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 702 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 754
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 755 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 804
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 805 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 859
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 860 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 904
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 905 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 964
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 965 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1016
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1017 KLFITDDELKKVHDFEE 1033
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 714 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 766
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 767 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 816
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 817 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 871
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 872 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 916
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 917 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 976
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 977 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1028
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1029 KLFITDDELKKVHDFEE 1045
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 80.5 bits (197), Expect = 6e-15
Identities = 76/377 (20%), Positives = 164/377 (43%), Gaps = 71/377 (18%)
Query: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGE 244
F P +KF +T +Y+ +L L +I + R P+ EW+++ ++ +
Sbjct: 865 FYNAPIVKFWFYTLAYIGYLMLF----NYIVLVKMERW---PSTQEWIVISYIFTLGIEK 917
Query: 245 IKQ--MWDGG-----LQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
+++ M + G ++ ++ ++WN+ D + L+ + L++ P S
Sbjct: 918 MREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMILRLQD-------QPFRS--- 967
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
++ + I+ +RL+ +F N +LGP + +G+M++D++ F+ I +VL++F
Sbjct: 968 -----DGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSF 1022
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL-YVTNVKAQ 416
+ F EE K I +W I+G + + Q
Sbjct: 1023 GVARQAILFPNEEPSWKLAKNI---------------FYMPYWMIYGEVFADQIDPPCGQ 1067
Query: 417 HEFTE--------------FVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEW 462
+E E ++ + Y +++ ++L+N+LIA+ NN++ + ++ W
Sbjct: 1068 NETREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVW 1127
Query: 463 KFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE----SFGT 518
KF R +L M++ E V+P P ++ + I+ HLC + + + + +G
Sbjct: 1128 KFQRYQLIMTFHER--------PVLPPPLIIFSHMTMIFQHLCCRWRKHESDPDERDYGL 1179
Query: 519 IGRRAADNLRRHHQYQE 535
D L++ H ++E
Sbjct: 1180 KLFITDDELKKVHDFEE 1196
>gi|239754785 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 80.1 bits (196), Expect = 8e-15
Identities = 56/180 (31%), Positives = 82/180 (45%), Gaps = 39/180 (21%)
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF-------------------- 283
E K++W G ++Y+ + WN++DF M ++ A + AF
Sbjct: 4 ECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDLT 63
Query: 284 -------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 336
VKY L RE W P +V+E L A+A + S + + AN GPLQ SL
Sbjct: 64 EVTLGDNVKYYNLARRE-WVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 337 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 396
G + DI +F+ I+ +V +AF G+ LY YY KQN AF+TL L+
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTLKRVLR 171
>gi|239749299 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 80.1 bits (196), Expect = 8e-15
Identities = 56/180 (31%), Positives = 82/180 (45%), Gaps = 39/180 (21%)
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF-------------------- 283
E K++W G ++Y+ + WN++DF M ++ A + AF
Sbjct: 4 ECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDLT 63
Query: 284 -------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 336
VKY L RE W P +V+E L A+A + S + + AN GPLQ SL
Sbjct: 64 EVTLGDNVKYYNLARRE-WVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 337 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 396
G + DI +F+ I+ +V +AF G+ LY YY KQN AF+TL L+
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTLKRVLR 171
>gi|239743393 PREDICTED: hypothetical protein XP_002342847, partial
[Homo sapiens]
Length = 182
Score = 80.1 bits (196), Expect = 8e-15
Identities = 56/180 (31%), Positives = 82/180 (45%), Gaps = 39/180 (21%)
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF-------------------- 283
E K++W G ++Y+ + WN++DF M ++ A + AF
Sbjct: 4 ECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDLT 63
Query: 284 -------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 336
VKY L RE W P +V+E L A+A + S + + AN GPLQ SL
Sbjct: 64 EVTLGDNVKYYNLARRE-WVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 337 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 396
G + DI +F+ I+ +V +AF G+ LY YY KQN AF+TL L+
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTLKRVLR 171
>gi|239509090 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 80.1 bits (196), Expect = 8e-15
Identities = 56/180 (31%), Positives = 82/180 (45%), Gaps = 39/180 (21%)
Query: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF-------------------- 283
E K++W G ++Y+ + WN++DF M ++ A + AF
Sbjct: 4 ECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDLT 63
Query: 284 -------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 336
VKY L RE W P +V+E L A+A + S + + AN GPLQ SL
Sbjct: 64 EVTLGDNVKYYNLARRE-WVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 337 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 396
G + DI +F+ I+ +V +AF G+ LY YY KQN AF+TL L+
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTLKRVLR 171
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 78.6 bits (192), Expect = 2e-14
Identities = 103/496 (20%), Positives = 184/496 (37%), Gaps = 101/496 (20%)
Query: 178 PKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWV 237
P + F P + F + SY FL L ++ D P P+ E I W+
Sbjct: 784 PAARARAFFTAPVVVFHLNILSYFAFLCLFA----YVLMVDFQ---PVPSWCECAIYLWL 836
Query: 238 LGFIWGEIKQMW----DGGLQD----YIHDWWNLMDFVMNSLYLATISLKIVAFVKYSAL 289
+ E++Q++ + GL Y D+WN +D L++A ++ +++ Y
Sbjct: 837 FSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPG- 895
Query: 290 NPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFI 349
+ ++ I LRL+ +FT + LGP I + RM+ D+ FLF+
Sbjct: 896 ---------------RVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFL 940
Query: 350 YCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLY 409
+ +++F + + E +G + + +IFG I Y
Sbjct: 941 LAVWVVSFGVAKQAILIHNERRVDWLFRG---------------AVYHSYLTIFGQIPGY 985
Query: 410 VTNVKAQHE-------------------------FTEFVGATMFGTYNVISLVVLLNMLI 444
+ V E F E++ + Y + + ++LLN+LI
Sbjct: 986 IDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLI 1045
Query: 445 AMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWI---- 500
AM N ++Q + +H D WKF R L Y P PF ++ L IK +
Sbjct: 1046 AMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAA-PPPFILL---SHLQLFIKRVVLKT 1101
Query: 501 --WTHLCKKKMRRKPESFGTIGRR--AADNLRRHHQYQEVMR---------NLVKRYVAA 547
H K K E + +N ++ Q+Q+ R N V V
Sbjct: 1102 PAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDISNKVDAMVDL 1161
Query: 548 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS---------TIQSANASKES 598
+ D G E+ L++ ++ + ++R + S T+ S A++E
Sbjct: 1162 LDLDPLKRSGSMEQRLASLEEQVAQTARALHWIVRTLRASGFSSEADVPTLASQKAAEEP 1221
Query: 599 SNSADSDEKSDSEGNS 614
+K++ G+S
Sbjct: 1222 DAEPGGRKKTEEPGDS 1237
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 65.1 bits (157), Expect = 2e-10
Identities = 73/323 (22%), Positives = 125/323 (38%), Gaps = 66/323 (20%)
Query: 189 PFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQM 248
P F+ + Y FLFL ++ D P+ E + WV + EI+Q
Sbjct: 731 PVTVFLGNVVMYFAFLFLFT----YVLLVDFRPPPQGPSGPEVTLYFWVFTLVLEEIRQ- 785
Query: 249 WDGGLQD-----------YIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDM 297
G D Y+ D WN D V L++ ++ +++ SA
Sbjct: 786 --GFFTDEDTHLVKKFTLYVGDNWNKCDMVAIFLFIVGVTCRMLP----SAFE------- 832
Query: 298 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 357
+ A+ + +LRLI +F + LGP I + RM+ D+ FLF + L+A+
Sbjct: 833 -----AGRTVLAMDFMVFTLRLIHIFAIHKQLGPKIIVVERMMKDVFFFLFFLSVWLVAY 887
Query: 358 ANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINL--------- 408
G+T + + L + IFG I L
Sbjct: 888 ---------------GVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARVN 932
Query: 409 -------YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIE 461
+ + ++ + T+ +++ V+L+N+LIAM + ++Q++ +AD+
Sbjct: 933 CSTHPLLLEDSPSCPSLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMF 992
Query: 462 WKFARTKLWMSYFEEGGTLPTPF 484
WKF R L + Y E P PF
Sbjct: 993 WKFQRYNLIVEYHERPALAP-PF 1014
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,968,898
Number of Sequences: 37866
Number of extensions: 1251935
Number of successful extensions: 4385
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 3914
Number of HSP's gapped (non-prelim): 478
length of query: 804
length of database: 18,247,518
effective HSP length: 110
effective length of query: 694
effective length of database: 14,082,258
effective search space: 9773087052
effective search space used: 9773087052
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.