Guide to the Human Genome
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Search of human proteins with 209447096

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
         (1320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]        2705   0.0  
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]          2650   0.0  
gi|38638698 KIAA1199 [Homo sapiens]                                   830   0.0  
gi|126116589 fibrocystin L [Homo sapiens]                             143   1e-33
gi|126131104 fibrocystin isoform 2 [Homo sapiens]                      65   3e-10
gi|126131102 fibrocystin isoform 1 [Homo sapiens]                      65   3e-10
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    49   2e-05
gi|20270363 family with sequence similarity 3, member D [Homo sa...    44   0.001
gi|13324682 family 3, member A protein [Homo sapiens]                  42   0.003
gi|91807125 family with sequence similarity 3, member C precurso...    42   0.005
gi|7661714 family with sequence similarity 3, member C precursor...    42   0.005
gi|46255032 family with sequence similarity 3, member B isoform ...    37   0.096
gi|46255030 family with sequence similarity 3, member B isoform ...    37   0.096
gi|29294649 dicer1 [Homo sapiens]                                      32   3.1  
gi|29294651 dicer1 [Homo sapiens]                                      32   3.1  
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    32   4.0  
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               32   5.3  
gi|62422571 collapsin response mediator protein 1 isoform 1 [Hom...    31   6.9  
gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo...    31   6.9  
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]         31   9.0  
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]         31   9.0  

>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
          Length = 1320

 Score = 2705 bits (7011), Expect = 0.0
 Identities = 1320/1320 (100%), Positives = 1320/1320 (100%)

Query: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
            MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60

Query: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
            AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120

Query: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
            RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL
Sbjct: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180

Query: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240
            IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW
Sbjct: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240

Query: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300
            TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF
Sbjct: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300

Query: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360
            LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS
Sbjct: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360

Query: 361  CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEETPQFLHMGEIIDGVDMRA 420
            CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEETPQFLHMGEIIDGVDMRA
Sbjct: 361  CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEETPQFLHMGEIIDGVDMRA 420

Query: 421  EVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQ 480
            EVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQ
Sbjct: 421  EVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQ 480

Query: 481  MGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGH 540
            MGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGH
Sbjct: 481  MGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGH 540

Query: 541  CFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVS 600
            CFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVS
Sbjct: 541  CFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVS 600

Query: 601  TFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHS 660
            TFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHS
Sbjct: 601  TFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHS 660

Query: 661  NFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNN 720
            NFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNN
Sbjct: 661  NFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNN 720

Query: 721  DNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGG 780
            DNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGG
Sbjct: 721  DNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGG 780

Query: 781  QNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLM 840
            QNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLM
Sbjct: 781  QNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLM 840

Query: 841  KNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDA 900
            KNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDA
Sbjct: 841  KNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDA 900

Query: 901  YVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLR 960
            YVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLR
Sbjct: 901  YVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLR 960

Query: 961  GINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQV 1020
            GINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQV
Sbjct: 961  GINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQV 1020

Query: 1021 TFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSY 1080
            TFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSY
Sbjct: 1021 TFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSY 1080

Query: 1081 CSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFT 1140
            CSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFT
Sbjct: 1081 CSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFT 1140

Query: 1141 SDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKT 1200
            SDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKT
Sbjct: 1141 SDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKT 1200

Query: 1201 VFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIF 1260
            VFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIF
Sbjct: 1201 VFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIF 1260

Query: 1261 LGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH 1320
            LGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH
Sbjct: 1261 LGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH 1320


>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
          Length = 1383

 Score = 2650 bits (6869), Expect = 0.0
 Identities = 1311/1383 (94%), Positives = 1316/1383 (95%), Gaps = 63/1383 (4%)

Query: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60
            MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF
Sbjct: 1    MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATF 60

Query: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120
            AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL
Sbjct: 61   AFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRL 120

Query: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180
            RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL
Sbjct: 121  RNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYIL 180

Query: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240
            IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW
Sbjct: 181  IQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASW 240

Query: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300
            TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF
Sbjct: 241  TLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEF 300

Query: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360
            LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS
Sbjct: 301  LRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTS 360

Query: 361  CNESVRNYENHSSGGKALAQREFYT---------------------------VDGQKFSV 393
            CNESVRNYENHSSGGKALAQREFYT                           VDG K ++
Sbjct: 361  CNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNL 420

Query: 394  -----------------TAYSEW-------------------IEETPQFLHMGEIIDGVD 417
                             T YS +                   ++ETPQFLHMGEIIDGVD
Sbjct: 421  LDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVD 480

Query: 418  MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 477
            MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG
Sbjct: 481  MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMG 540

Query: 478  QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 537
            QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT
Sbjct: 541  QQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDT 600

Query: 538  LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 597
            LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM
Sbjct: 601  LGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCM 660

Query: 598  AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 657
            AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR
Sbjct: 661  AVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNR 720

Query: 658  VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 717
            VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF
Sbjct: 721  VHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAF 780

Query: 718  KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 777
            KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF
Sbjct: 781  KNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGF 840

Query: 778  QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 837
            QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG
Sbjct: 841  QGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIG 900

Query: 838  FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 897
            FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY
Sbjct: 901  FLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGY 960

Query: 898  KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 957
            KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM
Sbjct: 961  KDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPM 1020

Query: 958  VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1017
            VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS
Sbjct: 1021 VLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTS 1080

Query: 1018 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1077
            FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG
Sbjct: 1081 FQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHG 1140

Query: 1078 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1137
            HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV
Sbjct: 1141 HSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQV 1200

Query: 1138 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1197
            VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT
Sbjct: 1201 VFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLT 1260

Query: 1198 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1257
            EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS
Sbjct: 1261 EKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGS 1320

Query: 1258 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1317
            TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS
Sbjct: 1321 TIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQAS 1380

Query: 1318 KAH 1320
            KAH
Sbjct: 1381 KAH 1383


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score =  830 bits (2143), Expect = 0.0
 Identities = 429/941 (45%), Positives = 594/941 (63%), Gaps = 40/941 (4%)

Query: 359  TSCNESVRNYENHSSGGK-----ALAQREFYTVDGQKFSVTAYSEW------IEETPQFL 407
            T+ N ++ N E++    K      +A  ++     ++F V            +   P +L
Sbjct: 417  TNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYL 476

Query: 408  HMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQ--CQFFDYDTFGGHIMIMKNFTS 465
            H+GE IDGVDMRAEVG+L+RNI++ GE+ED CY      C FFD+DTFGGHI     F +
Sbjct: 477  HIGEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKA 536

Query: 466  VHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTN 525
             HL   ELKHMGQQ +G+YP+HFHL GDVD +GGY   T++  LSIHH+FSRC+TVHG+N
Sbjct: 537  AHLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSN 596

Query: 526  GLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVF 585
            GLLIKD +G+++LGHCFF EDG E+RNT  H LGLL K GTLLP+DR++ MC  + +  +
Sbjct: 597  GLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSY 656

Query: 586  GNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKP 645
              YIP P  DC AVSTFW+A+PNNNLIN AAAGS++ G W++FH  PTG S G+      
Sbjct: 657  PGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYS 716

Query: 646  ELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKP 705
            E  PLG FYNNR HSN++AG+ ID GVKTT +SA D R +L +  SAR+ PHQDA+P KP
Sbjct: 717  EHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSI-ISARYSPHQDADPLKP 775

Query: 706  RVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSE 765
            R  A+I   IA+KN D+GAW+RGGD+ + +  FADNGIGLT AS G+FP D+GS QE+  
Sbjct: 776  REPAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKN 835

Query: 766  SLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKY 825
            SLFVGES N G +   N+  G GG+D   RTLP  + FPIRG Q+YDGPI++   TF+K+
Sbjct: 836  SLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKF 895

Query: 826  VPTPDRYSSAIGFLMKNSWQITPRNNISLVKF-GPHVSLNVFFGKPGPWFEDCEMDGDKN 884
            V    R++SA+ F + N+WQ  P NN++ + F    ++  VFFG+PGPWF   +MDGDK 
Sbjct: 896  VALEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKT 955

Query: 885  SIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLS 944
            S+FHD+DGSV+ Y  +Y+ + DN+L+RHP C+NV  W   ICSG YAQ+Y+Q + T NL 
Sbjct: 956  SVFHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLR 1015

Query: 945  MTITRDEYPSNPMVLRG-INQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKN 1003
            M I ++++PS+P+ L G + +   + QYQPVV L+KGYTIHW+  AP    ++L+NFNK 
Sbjct: 1016 MKIIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKG 1075

Query: 1004 DWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERK-FYFDSST 1062
            DWIRVGLCYP  T+F +      R     SK   +     ++++++    R  +Y+D  +
Sbjct: 1076 DWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDS 1135

Query: 1063 GLLFLYLKAKSHRHGHSYCSSQGCERVKIQA-ATDSKDISNCMAKAYPQYYRKPSVVKRM 1121
            GLLFL LKA++ R   ++CS +GCER+KI+A    +  +S+C A AYP++  +  V   M
Sbjct: 1136 GLLFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPM 1195

Query: 1122 PAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQR-GDPSVISVNGTDFTFRSA 1180
            P  L G          + T D    +L V+ +S  +       D + I V+G  +     
Sbjct: 1196 PKKLFG--------SQLKTKD---HFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSED 1244

Query: 1181 GVLLLVVDPCSVPFRLTEKTVFPLADVSRIE----EYLKTGIPPRSIVLLSTRGE-IKQL 1235
            G+ ++V+D      R+   T F  + +  I      Y+ T IP  SIVL++++G  + + 
Sbjct: 1245 GIQVVVID--GNQGRVVSHTSFRNSILQGIPWQLFNYVAT-IPDNSIVLMASKGRYVSRG 1301

Query: 1236 NISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFT 1276
              + +L  LG  +   L  K    F+GF G+F+P W  L T
Sbjct: 1302 PWTRVLEKLGADRGLKL--KEQMAFVGFKGSFRPIWVTLDT 1340



 Score =  217 bits (553), Expect = 5e-56
 Identities = 126/325 (38%), Positives = 186/325 (57%), Gaps = 10/325 (3%)

Query: 80  KNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGD 139
           +  F+  A+ + S+ + L    G +S  A    CPDQ+P L+ W+PG D    V I +G 
Sbjct: 6   RQDFLFKAMLTISW-LTLTCFPGATSTVAA--GCPDQSPELQPWNPGHDQDHHVHIGQGK 62

Query: 140 MLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSK 199
            L LTS ATV+SI I +GG LV    KD    I LRT +ILI +GG LH G+  C ++  
Sbjct: 63  TLLLTSSATVYSIHISEGGKLVI---KDHDEPIVLRTRHILIDNGGELHAGSALCPFQGN 119

Query: 200 ATITLYGKSDEG-ESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYT 258
            TI LYG++DEG +  P +G K+IGV  GG LELHG +K SWT L +TL+  G+  G Y 
Sbjct: 120 FTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYF 179

Query: 259 FEKDFS-RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDS 317
           FE+ +  RG+ V VID  +  ++ S+RFDT+  + ES RL ++L     GRI+++AV D 
Sbjct: 180 FERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDE 239

Query: 318 AAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKA 377
            +++ L    +    +LGS+    LG+R  W+ + V    S+S  + +  Y  H     A
Sbjct: 240 GSRN-LDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHI-EYHGHRGSAAA 297

Query: 378 LAQREFYTVDGQKFSVTAYSEWIEE 402
              + F T  G+ F+V+  SEW+++
Sbjct: 298 RVFKLFQTEHGEYFNVSLSSEWVQD 322


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score =  143 bits (361), Expect = 1e-33
 Identities = 94/295 (31%), Positives = 139/295 (47%), Gaps = 64/295 (21%)

Query: 406  FLHMGEII---DGV--DMRAEVGILTRNIVIQGE---------------------VEDSC 439
            + H+G  +   DG   + RAEVGILTRNI+I+G                         +C
Sbjct: 2364 YTHLGITVTLPDGTLFEARAEVGILTRNILIRGSDNVEWNNKIPACPDGFDTGEFATQTC 2423

Query: 440  YAENQCQFFDYDTFGGHIMIMK-----NFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGD 493
                  +    D FGG +M        N  +  + YVE+ H GQ  ++GRYP+H+HL GD
Sbjct: 2424 LQGKFGEEIGSDQFGGCVMFHAPVPGANMVTGRIEYVEVFHAGQAFRLGRYPIHWHLLGD 2483

Query: 494  VDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNT 553
            + +K      ++V G +IH +++R +T+H T+ LL++  I +D  G  FF+EDGIE  N 
Sbjct: 2484 LQFK------SYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNI 2537

Query: 554  LFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLIN 613
            L +NL +  +  T L                          D +  + FW+ +PNN + +
Sbjct: 2538 LQYNLAVFVQQSTSL------------------------LNDDVTPAAFWVTNPNNTIRH 2573

Query: 614  NAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 668
            NA AG    G WY  +  P G S    +  K    PLG F+NN VHS    G++I
Sbjct: 2574 NAVAGGTHFGFWYRMNNHPDGPSYDRNICQK--RVPLGEFFNNTVHSQGWFGMWI 2626



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 8/115 (6%)

Query: 133  VVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAE 192
            VVI +G  + L     +  +++  GG L+F +      +I L+   ILI DGG L IG E
Sbjct: 2198 VVITKGQTILLDQSTPILKMLLIQGGTLIFDE-----ADIELQAENILITDGGVLQIGTE 2252

Query: 193  KCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAR-KASWTLLART 246
               ++ KA ITL+G     E +P +G K + V   G L+LHG     +WT LA T
Sbjct: 2253 TSPFQHKAVITLHGHLRSPE-LPVYGAKTLAVRE-GILDLHGVPVPVTWTRLAHT 2305



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 44/134 (32%), Positives = 63/134 (47%), Gaps = 25/134 (18%)

Query: 418  MRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMI------MKNFT-SVHLSY 470
            + A+VGIL+RNI I GE             +  D+FG  +++      M  F  +  +S 
Sbjct: 3250 LAADVGILSRNIKIVGEDYPG---------WSEDSFGARVLVGSFTENMMTFKGNARISN 3300

Query: 471  VELKHMGQQQMG-----RYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTN 525
            VE  H GQ+        RY V F   G +   G    ++++ G + HH FS  I V GT+
Sbjct: 3301 VEFYHSGQEGFRDSTDPRYAVTFLNLGQIQEHG----SSYIRGCAFHHGFSPAIGVFGTD 3356

Query: 526  GLLIKDTIGFDTLG 539
            GL I D I   T+G
Sbjct: 3357 GLDIDDNIIHFTVG 3370



 Score = 35.8 bits (81), Expect = 0.28
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 12/116 (10%)

Query: 909  LIRHPSCVNVSKWNAVICSGT-YAQVYVQTWS----TQNLS-MTITRDEY------PSNP 956
            +IR  +C  + +W +  C G  YA + +++      T+ LS + I  + Y      P + 
Sbjct: 3744 IIRDSTCKYLPEWQSYQCFGMEYAMMVIESLDPDTETRRLSPVAIMGNGYVDLINGPQDH 3803

Query: 957  MVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCY 1012
                G   +     +  +V L K Y +++ G +P+   L L+N + N  + VG+ +
Sbjct: 3804 GWCAGYTCQRRLSLFHSIVALNKSYEVYFTGTSPQNLRLMLLNVDHNKAVLVGIFF 3859


>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
          Length = 3396

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 119  RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
            R  +W P +       V ++ G +L L ++ ++ +++   GG L+F         I LR 
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985

Query: 177  HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
            H IL+ DGG L IG+E   ++ +A ITLYG S      P +G KF+ V   GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 68/274 (24%), Positives = 114/274 (41%), Gaps = 49/274 (17%)

Query: 418  MRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-----M 458
            ++A V +L+R+I IQG + +       SC   N        C +   +   G       +
Sbjct: 2128 LKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDMGARV 2187

Query: 459  IMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRC 518
            I+++F     S V+LK +  Q +G+   H HL   +   G  R + F+ G ++ +SFSR 
Sbjct: 2188 IVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNSFSRG 2243

Query: 519  ITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPTDRNN 574
            +++ GT GL +   + ++ LGH   +    E R      +       +  G ++   RNN
Sbjct: 2244 LSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII---RNN 2300

Query: 575  SMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTG 634
             +      +   N       + +  S  +I  P N +  N   G   AG  Y FH   T 
Sbjct: 2301 VIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL-MTN 2350

Query: 635  ESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 668
            ++S   LL+         F  N  HS  + GLF+
Sbjct: 2351 QTSQAPLLS---------FTQNIAHSCTRYGLFV 2375



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 84/351 (23%), Positives = 126/351 (35%), Gaps = 118/351 (33%)

Query: 407  LHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMIMKNF 463
            +H+ E    + + AEVG+LTRNI IQ +V  SC        F     + F G + ++   
Sbjct: 2935 VHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQLLN-- 2990

Query: 464  TSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHG 523
                   VE+++ G            L   V++       +++   ++H S    I    
Sbjct: 2991 -------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGIHAAA 3032

Query: 524  TNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCTTMRD 582
            ++G+L+ D I F T GH   LE    Q  T+ +NL  L+T+P                  
Sbjct: 3033 SHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP------------------ 3071

Query: 583  KVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEPTGES 636
                           A ST W+A        + NL  N  AGS+  G     HK      
Sbjct: 3072 ---------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-----C 3111

Query: 637  SGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNSARFR 695
            S  +LL          + +N  HS+     L+ + G                LDN  R  
Sbjct: 3112 SSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNCTR-- 3143

Query: 696  PHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 745
                           I   +AFKN D GA +     + ++N    DN IGL
Sbjct: 3144 ---------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179


>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
          Length = 4074

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 119  RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
            R  +W P +       V ++ G +L L ++ ++ +++   GG L+F         I LR 
Sbjct: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985

Query: 177  HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
            H IL+ DGG L IG+E   ++ +A ITLYG S      P +G KF+ V   GTL LHG+
Sbjct: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 68/274 (24%), Positives = 114/274 (41%), Gaps = 49/274 (17%)

Query: 418  MRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-----M 458
            ++A V +L+R+I IQG + +       SC   N        C +   +   G       +
Sbjct: 2128 LKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDMGARV 2187

Query: 459  IMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRC 518
            I+++F     S V+LK +  Q +G+   H HL   +   G  R + F+ G ++ +SFSR 
Sbjct: 2188 IVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNSFSRG 2243

Query: 519  ITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPTDRNN 574
            +++ GT GL +   + ++ LGH   +    E R      +       +  G ++   RNN
Sbjct: 2244 LSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII---RNN 2300

Query: 575  SMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTG 634
             +      +   N       + +  S  +I  P N +  N   G   AG  Y FH   T 
Sbjct: 2301 VIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL-MTN 2350

Query: 635  ESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 668
            ++S   LL+         F  N  HS  + GLF+
Sbjct: 2351 QTSQAPLLS---------FTQNIAHSCTRYGLFV 2375



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 84/351 (23%), Positives = 126/351 (35%), Gaps = 118/351 (33%)

Query: 407  LHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMIMKNF 463
            +H+ E    + + AEVG+LTRNI IQ +V  SC        F     + F G + ++   
Sbjct: 2935 VHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQLLN-- 2990

Query: 464  TSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHG 523
                   VE+++ G            L   V++       +++   ++H S    I    
Sbjct: 2991 -------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGIHAAA 3032

Query: 524  TNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCTTMRD 582
            ++G+L+ D I F T GH   LE    Q  T+ +NL  L+T+P                  
Sbjct: 3033 SHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP------------------ 3071

Query: 583  KVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEPTGES 636
                           A ST W+A        + NL  N  AGS+  G     HK      
Sbjct: 3072 ---------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-----C 3111

Query: 637  SGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNSARFR 695
            S  +LL          + +N  HS+     L+ + G                LDN  R  
Sbjct: 3112 SSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNCTR-- 3143

Query: 696  PHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 745
                           I   +AFKN D GA +     + ++N    DN IGL
Sbjct: 3144 ---------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 261 KDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAK 320
           ++  RG++V V++Q T  ++    FDT+   +E   +  FL    PGR++   V D  + 
Sbjct: 125 REQGRGIHVIVLNQATGHVMAKRVFDTYS-PHEDEAMVLFLNMVAPGRVLICTVKDEGSF 183

Query: 321 SLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
            L + T + +   LGS+    LG+R  WA VG
Sbjct: 184 HL-KDTAKALLRSLGSQAGPALGWRDTWAFVG 214


>gi|20270363 family with sequence similarity 3, member D [Homo
           sapiens]
          Length = 224

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RGLN+ +++  T  +L  + FD   Y  +   L +FL+    G +V +A  D   
Sbjct: 94  KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355
             +   + ++  + LGS   + LG+R +W  +G  D
Sbjct: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186


>gi|13324682 family 3, member A protein [Homo sapiens]
          Length = 230

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 3/88 (3%)

Query: 265 RGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQ 324
           RGLN+ +++  + +++E+  FD   +  +   L +F+R    G +V +A  D  A  + +
Sbjct: 103 RGLNIALVNGVSGELIEARAFDM--WAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNE 160

Query: 325 GTIQMIQERLGSELIQGLGYRQAWALVG 352
            T ++  E LGS   + L +R +W  VG
Sbjct: 161 ETRKLFSE-LGSRNAKELAFRDSWVFVG 187


>gi|91807125 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186


>gi|7661714 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
           + +  RG+NV + +  T ++L+++ FD   +  +     EFL+    G IV +   D  A
Sbjct: 97  KNNVGRGINVALANGKTGEVLDTKYFDM--WGGDVAPFIEFLKAIQDGTIVLMGTYDDGA 154

Query: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVG 352
             L     ++I + LGS  I  LG+R  W   G
Sbjct: 155 TKLNDEARRLIAD-LGSTSITNLGFRDNWVFCG 186


>gi|46255032 family with sequence similarity 3, member B isoform b
           [Homo sapiens]
          Length = 187

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 58  ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116

Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162


>gi|46255030 family with sequence similarity 3, member B isoform a
           [Homo sapiens]
          Length = 235

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164

Query: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210


>gi|29294649 dicer1 [Homo sapiens]
          Length = 1922

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)

Query: 1156 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1202
            +K+E + G PS      T F F+       V+ P               V   LT  + F
Sbjct: 901  EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960

Query: 1203 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1262
            P  +     EY KT        L  T      L++ H    L L  P HL  KG  + L 
Sbjct: 961  PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015

Query: 1263 FSGNFKPSWTKL 1274
             +   K  W  L
Sbjct: 1016 SAEKRKAKWESL 1027


>gi|29294651 dicer1 [Homo sapiens]
          Length = 1922

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%)

Query: 1156 DKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDP-------------CSVPFRLTEKTVF 1202
            +K+E + G PS      T F F+       V+ P               V   LT  + F
Sbjct: 901  EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF 960

Query: 1203 PLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLG 1262
            P  +     EY KT        L  T      L++ H    L L  P HL  KG  + L 
Sbjct: 961  PSPEYETFAEYYKT-----KYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLS 1015

Query: 1263 FSGNFKPSWTKL 1274
             +   K  W  L
Sbjct: 1016 SAEKRKAKWESL 1027


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 13/88 (14%)

Query: 6   SRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASA-----KFTSIRREDRATF 60
           SRG +P  + P++      S       VP    PP K +        K    RRE+RA +
Sbjct: 93  SRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKY 152

Query: 61  AFS--------PEEQQAQRESQKQKRHK 80
             +         E+ +A RE Q Q+R +
Sbjct: 153 LAAKKAVWLEKEEKAKALREKQLQERRR 180


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 20  NSRHPSGYVPGKVVPLR-----PPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQ 74
           +S+ P+G  P   VP R     PPPPP   A+          R+     P +   Q   +
Sbjct: 362 HSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGE 421

Query: 75  KQKRHKNTFIC 85
           ++  + ++ IC
Sbjct: 422 RELPNSHSMIC 432


>gi|62422571 collapsin response mediator protein 1 isoform 1 [Homo
           sapiens]
          Length = 686

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 763 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 818
           +S+   V E  N     G  +++      +    R   RN+ F ++G    +YDGP++  
Sbjct: 561 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 620

Query: 819 RSTFKKYVPTPDRYSS 834
            +T K   P P   SS
Sbjct: 621 PATPKYATPAPSAKSS 636


>gi|4503051 collapsin response mediator protein 1 isoform 2 [Homo
           sapiens]
          Length = 572

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 763 VSESLFVGESRNYGFQGGQNKYVGTGGIDQK--PRTLPRNRTFPIRGFQ--IYDGPIHLT 818
           +S+   V E  N     G  +++      +    R   RN+ F ++G    +YDGP++  
Sbjct: 447 ISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEV 506

Query: 819 RSTFKKYVPTPDRYSS 834
            +T K   P P   SS
Sbjct: 507 PATPKYATPAPSAKSS 522


>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
          Length = 845

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
           DS AK L+   +++IQ  L     G +  +       +GY           GG ++   S
Sbjct: 529 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 588

Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
           V+  E+H + G +  Q+E   +D QK  ++
Sbjct: 589 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 618


>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
          Length = 854

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 316 DSAAKSLLQGTIQMIQERL-----GSELIQG------LGYRQAWALVGVIDGGSTSCNES 364
           DS AK L+   +++IQ  L     G +  +       +GY           GG ++   S
Sbjct: 538 DSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALS 597

Query: 365 VRNYENHSSGGKALAQREFYTVDGQKFSVT 394
           V+  E+H + G +  Q+E   +D QK  ++
Sbjct: 598 VKQLESHRAPGPSTCQKENQHLDSQKMDMS 627


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,185,191
Number of Sequences: 37866
Number of extensions: 2541799
Number of successful extensions: 7100
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 7041
Number of HSP's gapped (non-prelim): 41
length of query: 1320
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1206
effective length of database: 13,930,794
effective search space: 16800537564
effective search space used: 16800537564
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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