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Search of human proteins with 208022637
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo
sapiens]
(586 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo sapi... 1168 0.0
gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo sapi... 926 0.0
gi|4758012 clathrin heavy chain 1 [Homo sapiens] 69 2e-11
gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo ... 66 8e-11
gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo ... 66 8e-11
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 39 0.017
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 38 0.023
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 38 0.023
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 38 0.023
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 37 0.066
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 37 0.066
gi|110227629 translin-associated factor X interacting protein 1 ... 36 0.086
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 36 0.11
gi|214010216 SMC6 protein [Homo sapiens] 35 0.15
gi|13375848 SMC6 protein [Homo sapiens] 35 0.15
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 35 0.15
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.25
gi|55770834 centromere protein F [Homo sapiens] 33 0.56
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog... 33 0.73
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 32 1.2
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 32 1.6
gi|28416946 myosin 18A isoform a [Homo sapiens] 32 1.6
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 32 2.1
gi|7706093 toll-like receptor 7 [Homo sapiens] 32 2.1
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 32 2.1
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 32 2.1
gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog... 32 2.1
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 31 2.8
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 31 2.8
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 31 2.8
>gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo
sapiens]
Length = 586
Score = 1168 bits (3021), Expect = 0.0
Identities = 586/586 (100%), Positives = 586/586 (100%)
Query: 1 MSVHQIRKHAVLPPIICRSDKEFLESVQRYIITETERLGCSEEGPADEYYIIYRNVFDKV 60
MSVHQIRKHAVLPPIICRSDKEFLESVQRYIITETERLGCSEEGPADEYYIIYRNVFDKV
Sbjct: 1 MSVHQIRKHAVLPPIICRSDKEFLESVQRYIITETERLGCSEEGPADEYYIIYRNVFDKV 60
Query: 61 IEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYRKRTIQLE 120
IEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYRKRTIQLE
Sbjct: 61 IEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYRKRTIQLE 120
Query: 121 AKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALT 180
AKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALT
Sbjct: 121 AKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALT 180
Query: 181 KYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQI 240
KYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQI
Sbjct: 181 KYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQI 240
Query: 241 ISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIER 300
ISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIER
Sbjct: 241 ISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIER 300
Query: 301 FNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHA 360
FNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHA
Sbjct: 301 FNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHA 360
Query: 361 FPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCL 420
FPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCL
Sbjct: 361 FPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCL 420
Query: 421 ALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCL 480
ALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCL
Sbjct: 421 ALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCL 480
Query: 481 TKELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQ 540
TKELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQ
Sbjct: 481 TKELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQ 540
Query: 541 EVANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW 586
EVANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW
Sbjct: 541 EVANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW 586
>gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo
sapiens]
Length = 464
Score = 926 bits (2392), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 123 MRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALTKY 182
MRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALTKY
Sbjct: 1 MRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALTKY 60
Query: 183 MKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQIIS 242
MKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQIIS
Sbjct: 61 MKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQIIS 120
Query: 243 QALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIERFN 302
QALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIERFN
Sbjct: 121 QALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIERFN 180
Query: 303 ELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHAFP 362
ELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHAFP
Sbjct: 181 ELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFITSHAFP 240
Query: 363 CPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCLAL 422
CPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCLAL
Sbjct: 241 CPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNKAKCLAL 300
Query: 423 AQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCLTK 482
AQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCLTK
Sbjct: 301 AQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTDDLLQLLMSCPQVELIQCLTK 360
Query: 483 ELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQEV 542
ELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQEV
Sbjct: 361 ELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQEV 420
Query: 543 ANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW 586
ANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW
Sbjct: 421 ANICSQNGFDKLSNDITSILRSQAAVTEISEEDDAVNLMEHVFW 464
>gi|4758012 clathrin heavy chain 1 [Homo sapiens]
Length = 1675
Score = 68.6 bits (166), Expect = 2e-11
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 15/160 (9%)
Query: 297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 356
+ +FN L + G Y +AA AAN+P+ ILR T+ F++V G+ PLL +F L
Sbjct: 364 FARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLD 423
Query: 357 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 416
++ +LE + L + R L+ W+ +++L SEE GD++ K
Sbjct: 424 QGQ-----LNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
Query: 417 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 456
+ LA VY + K I C + GQ +++ Y +++
Sbjct: 469 SVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKV 508
>gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
sapiens]
Length = 1583
Score = 66.2 bits (160), Expect = 8e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 15/160 (9%)
Query: 297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 356
++ +FN L + G Y +AA AA++P+ ILR T+ F+++ G+ PLL +F L
Sbjct: 364 FVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGILLD 423
Query: 357 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 416
++ +LE L + R L+ W+ +++L SEE GD++ K
Sbjct: 424 QGQ-----LNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
Query: 417 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 456
LA VY + K I C + GQ +++ Y +++
Sbjct: 469 TTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKV 508
>gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo
sapiens]
Length = 1640
Score = 66.2 bits (160), Expect = 8e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 15/160 (9%)
Query: 297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 356
++ +FN L + G Y +AA AA++P+ ILR T+ F+++ G+ PLL +F L
Sbjct: 364 FVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGILLD 423
Query: 357 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 416
++ +LE L + R L+ W+ +++L SEE GD++ K
Sbjct: 424 QGQ-----LNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
Query: 417 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 456
LA VY + K I C + GQ +++ Y +++
Sbjct: 469 TTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKV 508
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 38.5 bits (88), Expect = 0.017
Identities = 54/184 (29%), Positives = 89/184 (48%), Gaps = 16/184 (8%)
Query: 54 RNVFDKVIEHITAYKSILTSIKKEYD--AFIETIKKDRRTTFCLHGKLKGLAAEPTALVY 111
RN +K + IT + +KKE D A +E +KK+ T +L+ AE AL
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTV-KDLQLRLDEAEQLALKG 1811
Query: 112 YRKRTIQLEAKMRIIESN-SSKIQSQIDHIKQCRA-EYDTKEVKYCTFSKDPSKPIPGMT 169
+K+ +LEA++R +ES S+ + ++ +K R E KE+ Y T ++ K I +
Sbjct: 1812 GKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQT--EEDRKNI--LR 1867
Query: 170 LQESMN-LDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLN 228
LQ+ ++ L K K ++ E L K+ RK L E+ +R D+AE+
Sbjct: 1868 LQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKF----RK--LQHELEEAKERADIAESQV 1921
Query: 229 KKLQ 232
KL+
Sbjct: 1922 NKLR 1925
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.1 bits (87), Expect = 0.023
Identities = 43/219 (19%), Positives = 98/219 (44%), Gaps = 15/219 (6%)
Query: 90 RTTFCLHGKLKGLAAEPTALVYYRKRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDT 149
RT+ K L E L R ++LE + + + ++++ +D ++ ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELT--SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Query: 150 KEVKYCTFSKDPSKPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKAD 209
E + SK + + +QE +L K L + A++++ + + +
Sbjct: 496 MEKENQRLSKKV-EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI-------ETLRE 547
Query: 210 LDEEMIVLLKRRDVAENLNKKLQFCHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKY 269
E I +L++ + E+LN+ + QR QI ++A ++ + + E K
Sbjct: 548 NSERQIKILEQEN--EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSK 605
Query: 270 LQGDQGIVEELME---DDPRRAKEAEIMLHYIERFNELI 305
++ ++ +++ +E + RA+E E LH++E+ NEL+
Sbjct: 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELL 644
Score = 36.2 bits (82), Expect = 0.086
Identities = 53/248 (21%), Positives = 101/248 (40%), Gaps = 24/248 (9%)
Query: 58 DKVIEHITAYKSILTSIKKEYDAFIETIKKDRR----TTFCLHGKLKGLAAEPTALVYYR 113
DK+ ++ YK L I+ Y A +E +K+D + T L +L+G A L
Sbjct: 323 DKLESEVSRYKERLHDIEF-YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELE 381
Query: 114 KRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQES 173
K +QL+AK+ +E + +I+ + + + + + S D S + Q S
Sbjct: 382 KENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ----SMDESLHLGWELEQIS 437
Query: 174 MNLDALTKYMKHLEDKYAEIKQAMLIKY-VPAQRKADLDEEMIVLLKRRDVAENLNKKLQ 232
+ K L + E+ + L+K + Q EE+ + + + K++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 233 FCHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAE 292
+QRL + L + E +Q+ + LQ Q + ++LM++ + K E
Sbjct: 498 KENQRLSKKVEILEN--------------EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 293 IMLHYIER 300
+ ER
Sbjct: 544 TLRENSER 551
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 38.1 bits (87), Expect = 0.023
Identities = 43/219 (19%), Positives = 98/219 (44%), Gaps = 15/219 (6%)
Query: 90 RTTFCLHGKLKGLAAEPTALVYYRKRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDT 149
RT+ K L E L R ++LE + + + ++++ +D ++ ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELT--SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Query: 150 KEVKYCTFSKDPSKPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKAD 209
E + SK + + +QE +L K L + A++++ + + +
Sbjct: 496 MEKENQRLSKKV-EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI-------ETLRE 547
Query: 210 LDEEMIVLLKRRDVAENLNKKLQFCHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKY 269
E I +L++ + E+LN+ + QR QI ++A ++ + + E K
Sbjct: 548 NSERQIKILEQEN--EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSK 605
Query: 270 LQGDQGIVEELME---DDPRRAKEAEIMLHYIERFNELI 305
++ ++ +++ +E + RA+E E LH++E+ NEL+
Sbjct: 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELL 644
Score = 36.2 bits (82), Expect = 0.086
Identities = 53/248 (21%), Positives = 101/248 (40%), Gaps = 24/248 (9%)
Query: 58 DKVIEHITAYKSILTSIKKEYDAFIETIKKDRR----TTFCLHGKLKGLAAEPTALVYYR 113
DK+ ++ YK L I+ Y A +E +K+D + T L +L+G A L
Sbjct: 323 DKLESEVSRYKERLHDIEF-YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELE 381
Query: 114 KRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQES 173
K +QL+AK+ +E + +I+ + + + + + S D S + Q S
Sbjct: 382 KENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ----SMDESLHLGWELEQIS 437
Query: 174 MNLDALTKYMKHLEDKYAEIKQAMLIKY-VPAQRKADLDEEMIVLLKRRDVAENLNKKLQ 232
+ K L + E+ + L+K + Q EE+ + + + K++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497
Query: 233 FCHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAE 292
+QRL + L + E +Q+ + LQ Q + ++LM++ + K E
Sbjct: 498 KENQRLSKKVEILEN--------------EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 293 IMLHYIER 300
+ ER
Sbjct: 544 TLRENSER 551
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 38.1 bits (87), Expect = 0.023
Identities = 60/234 (25%), Positives = 104/234 (44%), Gaps = 34/234 (14%)
Query: 19 SDKEFLESVQRYIITETERLGCSEE------------GPADEYYIIYRNVFDKVIEHITA 66
+++E LE+ +R + ++ G + G +E R +K + IT
Sbjct: 1751 AEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITD 1810
Query: 67 YKSILTSIKKEYD--AFIETIKKD-RRTTFCLHGKLKGLAAEPTALVYYRKRTIQLEAKM 123
+ +KKE D A +E +KK +T L +L+ AE AL +K+ +LEAK+
Sbjct: 1811 AAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLE--EAEQAALRGGKKQVQKLEAKV 1868
Query: 124 RIIESN-SSKIQSQIDHIKQCRA-EYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALTK 181
R +E+ ++ + + +K R E KE+ Y +++ K + M +D L
Sbjct: 1869 RELEAELDAEQKKHAEALKGVRKHERRVKELAY--QAEEDRKNLARM----QDLVDKLQS 1922
Query: 182 YMKHLEDKYAEIKQ---AMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQ 232
+K + ++ E +Q L KY AQ + D EE R D+AE KL+
Sbjct: 1923 KVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE------RADMAETQANKLR 1970
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 36.6 bits (83), Expect = 0.066
Identities = 50/248 (20%), Positives = 104/248 (41%), Gaps = 23/248 (9%)
Query: 54 RNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYR 113
R K EH + L ++++E+ +T+K++ R L + + L AE
Sbjct: 475 REQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRK---LEEENENLRAELQCCSTQL 531
Query: 114 KRTI-QLEAKMRIIESNSSKIQSQIDHIKQCRAEYDT---KEVKYC--TFSKDPSKPIPG 167
+ ++ + ++I+ + +I Q + + +A+ D KE Y T +K+
Sbjct: 532 ESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEA---YDA 588
Query: 168 MTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENL 227
++ + + D LT+ ++ L +E K ++KA L+EE+I +R
Sbjct: 589 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 648
Query: 228 NKKLQFCHQ-----------RLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGI 276
+KL+ HQ +L+ +S + W K + ++ Q ++ + +
Sbjct: 649 LRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAAL 708
Query: 277 VEELMEDD 284
E L+EDD
Sbjct: 709 KENLLEDD 716
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 36.6 bits (83), Expect = 0.066
Identities = 50/248 (20%), Positives = 104/248 (41%), Gaps = 23/248 (9%)
Query: 54 RNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYR 113
R K EH + L ++++E+ +T+K++ R L + + L AE
Sbjct: 620 REQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRK---LEEENENLRAELQCCSTQL 676
Query: 114 KRTI-QLEAKMRIIESNSSKIQSQIDHIKQCRAEYDT---KEVKYC--TFSKDPSKPIPG 167
+ ++ + ++I+ + +I Q + + +A+ D KE Y T +K+
Sbjct: 677 ESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEA---YDA 733
Query: 168 MTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENL 227
++ + + D LT+ ++ L +E K ++KA L+EE+I +R
Sbjct: 734 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 793
Query: 228 NKKLQFCHQ-----------RLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGI 276
+KL+ HQ +L+ +S + W K + ++ Q ++ + +
Sbjct: 794 LRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAAL 853
Query: 277 VEELMEDD 284
E L+EDD
Sbjct: 854 KENLLEDD 861
>gi|110227629 translin-associated factor X interacting protein 1
[Homo sapiens]
Length = 658
Score = 36.2 bits (82), Expect = 0.086
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 22 EFLESVQRYIITETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKEYDAF 81
++LE ++ Y+ E L + + YR +F+ IE YK +L+SIK Y+
Sbjct: 46 QYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGM 105
Query: 82 IETIKKDRRTTFCLHGKL 99
+ ++ R L KL
Sbjct: 106 LAHQREKIRALEPLKAKL 123
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/157 (20%), Positives = 74/157 (47%), Gaps = 18/157 (11%)
Query: 113 RKRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQE 172
+K + E + ++E + ++ S+ +H+K+ + +Y+ ++ + + + + ++
Sbjct: 1176 QKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQ 1235
Query: 173 SM---NLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNK 229
SM +L+ ++Y +LED+ ++K+ + Q + L E R A +
Sbjct: 1236 SMSEASLEVTSRYRINLEDETQDLKKKL------GQIRNQLQEAQ----DRHTEAVRCAE 1285
Query: 230 KLQFCHQRLQIISQALSSWVKSDMSSPFQDFVEQIQK 266
K+Q Q+L+ + L VK M D +E++QK
Sbjct: 1286 KMQDHKQKLEKDNAKLKVTVKKQM-----DKIEELQK 1317
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 35.4 bits (80), Expect = 0.15
Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 30/168 (17%)
Query: 120 EAKMRIIESNSSKIQSQIDHIKQCRAE----YDTKEVKYCTFSK--DPSKPIPGMTLQES 173
++KM+++E + + + ++H+K + E YD + K S+ DP K + L +S
Sbjct: 749 KSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLK--DELNLADS 806
Query: 174 MNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQF 233
+D + +H E+K E + ++K +LD +K +++ E +++ Q
Sbjct: 807 -EVDNQKRGKRHYEEKQKEHLDTL------NKKKRELD------MKEKELEEKMSQARQI 853
Query: 234 CHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELM 281
C +R+++ A S + ++IQ GD+ EE+M
Sbjct: 854 CPERIEVEKSA------SILDKEINRLRQKIQAEHASHGDR---EEIM 892
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 35.4 bits (80), Expect = 0.15
Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 30/168 (17%)
Query: 120 EAKMRIIESNSSKIQSQIDHIKQCRAE----YDTKEVKYCTFSK--DPSKPIPGMTLQES 173
++KM+++E + + + ++H+K + E YD + K S+ DP K + L +S
Sbjct: 749 KSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLK--DELNLADS 806
Query: 174 MNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQF 233
+D + +H E+K E + ++K +LD +K +++ E +++ Q
Sbjct: 807 -EVDNQKRGKRHYEEKQKEHLDTL------NKKKRELD------MKEKELEEKMSQARQI 853
Query: 234 CHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGIVEELM 281
C +R+++ A S + ++IQ GD+ EE+M
Sbjct: 854 CPERIEVEKSA------SILDKEINRLRQKIQAEHASHGDR---EEIM 892
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 35.4 bits (80), Expect = 0.15
Identities = 62/315 (19%), Positives = 135/315 (42%), Gaps = 44/315 (13%)
Query: 24 LESVQRYIIT------ETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKE 77
LE VQR + ETE++ E+ +Y + V E ++ +S ++++
Sbjct: 1000 LERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQ----ESVEERLSQLQSENMLLRQQ 1055
Query: 78 YDAFIETIKKDRRTTFCL----HGKLKGLAAEPTALVYYRKRTIQLEAKMRIIESNSSKI 133
D + +T+ + H K L AE K+ + L+ K + + + +
Sbjct: 1056 LDDAHKKANSQEKTSSTIQDQFHSAAKNLQAES------EKQILSLQEKNKELMDEYNHL 1109
Query: 134 QSQIDHIKQCRA--EYDTKEVKYCTFSK----DPSKPIPGMTLQESM-NLDALTKYMKHL 186
+ ++D ++ +A + D E + S+ D + + LQ+++ ++ A+ K + L
Sbjct: 1110 KERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEV--LQLQQTLFSMKAIQKQCETL 1167
Query: 187 EDKYAEIKQAMLIKYVPAQR------KADLDEEMIVLLKRRDVAENLN-------KKLQF 233
+ ++KQ ++ +R KA+ + +I R+++ E LN K+
Sbjct: 1168 QKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAV 1227
Query: 234 CHQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGD--QGIVEELMEDDPRRAKEA 291
H++L + + ++ +K+ M +D +I + K Q D + +E E K
Sbjct: 1228 SHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVR 1287
Query: 292 EIMLHYIERFNELIS 306
E + + + R NE+I+
Sbjct: 1288 ESLSNELSRTNEMIA 1302
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 34.7 bits (78), Expect = 0.25
Identities = 36/174 (20%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 32 ITETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKE-------YDAFIET 84
I E E L EE E I+ K ++ L +IKKE D+F+++
Sbjct: 2410 IKELENLLSQEE----EENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKS 2465
Query: 85 IKKDRRTTFCLHGKLKGLAAEPTALVYYRKRTIQ-LEAKMRIIESNSSKIQSQIDHIKQC 143
+ + + G + L +++ + + IQ A+ ++ ++S +D +
Sbjct: 2466 MSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE 2525
Query: 144 RAEYDTKEVKYCTFSKDPSKPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAM 197
A+ D + ++Y +D ++ I Q+ L+ + K LE+KYA++++ +
Sbjct: 2526 NAKLDAELIQY---REDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2576
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 33.5 bits (75), Expect = 0.56
Identities = 88/444 (19%), Positives = 181/444 (40%), Gaps = 45/444 (10%)
Query: 112 YRKRTIQLE-AKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTL 170
+++ +QLE AK+ +IE + + D + + A+YD KY + K ++
Sbjct: 315 FQELQLQLEKAKVELIEKEKVLNKCR-DELVRTTAQYDQASTKYTALEQKLKKLTEDLSC 373
Query: 171 QESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKK 230
Q A + +++K E ++ + + Q LD+E I + R L ++
Sbjct: 374 QRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQ---TLDQECIQMKAR------LTQE 424
Query: 231 LQFC---HQRLQIISQALSSWVKSDMSSPFQDFVEQIQKTKYLQGDQGI-VEELMEDDPR 286
LQ H LQ L+S VK + + ++F K K + +Q ++ E++ R
Sbjct: 425 LQQAKNMHNVLQAELDKLTS-VKQQLENNLEEF-----KQKLCRAEQAFQASQIKENELR 478
Query: 287 RAKEAEIMLHYIERFNELISLGEYEKA--ACYAANSPRRILRNIGTMNTFKAVGKIRGKP 344
R+ E +++ N L+ +KA C+ + I + + F K +
Sbjct: 479 RSMEE------MKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTS 532
Query: 345 LPLLLFFEALFITSHAFPCPVDAALTLEGIKCGLS--EKRLDLVTNWVTQERLTFSEEAG 402
+L I + +LTLE +K ++ EK+ D + + ++R E+
Sbjct: 533 QETMLRDLQEKINQQ------ENSLTLEKLKLAVADLEKQRDCSQD-LLKKREHHIEQLN 585
Query: 403 DVICDYGEQDTYNKAKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQLKDFTTD 462
D + E+++ L L + Y E L ++ L C + + +++ ++ K+
Sbjct: 586 DKL-SKTEKESKALLSALELKKKEYEE--LKEEKTLFSCWKSENEKLLTQMESEKE-NLQ 641
Query: 463 DLLQLLMSCPQVELIQCLTKELNEKQPSLSFGLAILHLFSADMKKVGIKLLQEINKGGID 522
+ L +C + + I+ + E NE+ +L L + ++ V E+ +
Sbjct: 642 SKINHLETCLKTQQIK--SHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLA 699
Query: 523 AVESLMINDSFCSIEKWQEVANIC 546
+E L F + +E+ N+C
Sbjct: 700 YME-LQQKAEFSDQKHQKEIENMC 722
Score = 30.4 bits (67), Expect = 4.7
Identities = 43/221 (19%), Positives = 93/221 (42%), Gaps = 37/221 (16%)
Query: 54 RNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYR 113
+++ K HI L+ +KE A + ++ ++ + + L E T ++
Sbjct: 571 QDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKK-------EYEELKEEKTLFSCWK 623
Query: 114 KRTIQLEAKMRIIESNSSKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQES 173
+L +M ES +QS+I+H++ C T+++K S + ++ + + +
Sbjct: 624 SENEKLLTQM---ESEKENLQSKINHLETC---LKTQQIK----SHEYNERVRTLEMDRE 673
Query: 174 MNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEM------IVLLKRRDV---A 224
NL + + ++ D + + + Y+ Q+KA+ ++ + LK +
Sbjct: 674 -NLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQV 732
Query: 225 ENLNKKLQF----------CHQRLQIISQALSSWVKSDMSS 255
E+L KLQ C+Q L ++L +KS +S
Sbjct: 733 EDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDAS 773
>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
[Homo sapiens]
Length = 766
Score = 33.1 bits (74), Expect = 0.73
Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 204 AQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQIISQ----ALSSWVKSDMSSPFQD 259
A+ + +EE +LL+ + ++L K+ + SQ + S V S++ + Q
Sbjct: 407 AEERPVAEEE--ILLREFEERQSLRKRSELNQDAEPASSQETKDSSSQEVLSELRALSQK 464
Query: 260 FVEQIQKTKYLQGDQGIVEELMEDDPRRAKEAEIMLHYIERFNELISLGEYEKAACYAAN 319
E+ Q K +G V ++ ++P + ++L ER L L E K C+
Sbjct: 465 LKEKHQSRKQKASSEGTVPQVQREEPAPEEAEPLLLQRSERVQTLEELEELGKEDCFQNK 524
Query: 320 S-PRRIL 325
PR +L
Sbjct: 525 ELPRPVL 531
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 32.3 bits (72), Expect = 1.2
Identities = 44/210 (20%), Positives = 88/210 (41%), Gaps = 41/210 (19%)
Query: 59 KVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTF--------CLHGKLKGLAAEPTALV 110
+++EH T LT KE +E R C K+K + E +L
Sbjct: 319 QLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLK 378
Query: 111 YYRKRT----IQLEAKMRIIESNSSKIQSQIDHI--KQCRAEYDTKEV------------ 152
++ +QL K+ +E ++++QS++D++ Q + E +T+E+
Sbjct: 379 KKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLPRLPF 438
Query: 153 ------KYCTFSKDPSKPIPGMTLQESMNLDALTKY----MKHLEDKYAEIKQAMLIKYV 202
+C S P ++ +LD +T + H+ + I++++ ++
Sbjct: 439 RQNDSSSHCQKSGSPISS-EERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQ-- 495
Query: 203 PAQRKADLDEEMIVLLKRRDVAENLNKKLQ 232
Q+K + EEM L + +AE LN K++
Sbjct: 496 -KQQKQNY-EEMQAKLAAQKLAERLNIKMR 523
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 32.0 bits (71), Expect = 1.6
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 20/139 (14%)
Query: 453 IQQLKDFTTDDLLQL--------------LMSCPQVELIQCLTKELNEKQPSLSFGLAIL 498
I+Q+++F T D L + S PQ +Q LT+++ E+ SLS IL
Sbjct: 1504 IKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQ--LQNLTEDIRERVESLSQVEVIL 1561
Query: 499 HLFSADMKKVGIKLLQEINKGGIDAVESLMINDSFCSIEKWQEVANICSQNGFDKLSNDI 558
+AD+ + + LL+E + A + + D + E A + ++ + DI
Sbjct: 1562 QHSAADIARAEM-LLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI 1620
Query: 559 ---TSILRSQAAVTEISEE 574
++L S + T SEE
Sbjct: 1621 QGTQNLLTSIESETAASEE 1639
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 32.0 bits (71), Expect = 1.6
Identities = 53/259 (20%), Positives = 106/259 (40%), Gaps = 39/259 (15%)
Query: 58 DKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPTA--------- 108
D + + TA + L+ +++E + +++D+ L K K A+ +
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 109 --LVYYRKRTIQLEAKMRIIESNSSKI-QSQIDHIKQCRAEYDTKEVKY-CTFSKDPSKP 164
L K +L+ K++ ++S + QS +D R E +E++ F + K
Sbjct: 1781 AQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKR 1840
Query: 165 IPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVA 224
+ + + N++ LT+ + + AE ++ K + Q + D EEM L ++ A
Sbjct: 1841 LESLASRLKENMEKLTE--ERDQRIAAENREKEQNKRLQRQLR-DTKEEMGELARKEAEA 1897
Query: 225 ENLNKKLQFCHQRLQIISQALSSWVK----------------------SDMSSPFQDFVE 262
+L+ + L+ +Q+L + +K D+ + QD V
Sbjct: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVT 1957
Query: 263 QIQKTK-YLQGDQGIVEEL 280
+ QK K L+GD + EL
Sbjct: 1958 KYQKRKNKLEGDSDVDSEL 1976
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 31.6 bits (70), Expect = 2.1
Identities = 44/240 (18%), Positives = 106/240 (44%), Gaps = 28/240 (11%)
Query: 22 EFLESVQRYIITETERLGCSEE--GPADEYYIIYRNVFDKVIEHITAYKSILTSIKKEYD 79
E E+++R + ERL ++ + + + + ++ + + A + +T+ + +Y
Sbjct: 265 EAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYF 324
Query: 80 AFIETIKKDRRTTFCLHGKLKGLAAEPTALVYYRKRTIQLEAKMRIIESNSSKIQSQIDH 139
+F E I R + G + E T L R+ + E++ R++ ++I ++
Sbjct: 325 SFREKIAALLRGRLSMTG-----STEDTILEKIREMDSREESRDRMVSQLEAQISELVEQ 379
Query: 140 I-----------KQCRAEYDTKEVKYCTFSKDPSKPIPGMTLQESMN---------LDAL 179
+ ++ + + E + ++ + G L++++N LD L
Sbjct: 380 LGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQL 439
Query: 180 TKYMKHLEDKYAEIKQAMLIKYVPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQ 239
++ MK L+ AE+ M + V A+ + + E +++ + +A NL +KL+ +RL+
Sbjct: 440 SQKMK-LDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLE 498
>gi|7706093 toll-like receptor 7 [Homo sapiens]
Length = 1049
Score = 31.6 bits (70), Expect = 2.1
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query: 150 KEVKYCTFSKD--PSKPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKYVPAQRK 207
K C +D P +P+ L +S+ L T ++ + DKYA+ + + Y+ QR
Sbjct: 922 KHFNLCLEERDWLPGQPVLE-NLSQSIQLSKKTVFV--MTDKYAKTENFKIAFYLSHQRL 978
Query: 208 ADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQIISQALSSWVKSDMSSPF 257
D ++I+L+ E +K +F R ++ ++ W + + P+
Sbjct: 979 MDEKVDVIILI----FLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPY 1024
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 31.6 bits (70), Expect = 2.1
Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 145 AEYDTKEVK--YCTFSKDPSKP-IPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKY 201
A+ D+K ++ Y + PSKP P ++++++ + L+ LED+ A + +
Sbjct: 272 AQKDSKRIQKEYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEE- 330
Query: 202 VPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQI---ISQALSSW 248
AQ+ EEM+V K+R++ E +K Q +R ++ I A+ +W
Sbjct: 331 --AQKHRQQYEEMVVQAKKRELKEAQRRKKQL-EERCRVEESIGNAVLTW 377
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 31.6 bits (70), Expect = 2.1
Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 145 AEYDTKEVK--YCTFSKDPSKP-IPGMTLQESMNLDALTKYMKHLEDKYAEIKQAMLIKY 201
A+ D+K ++ Y + PSKP P ++++++ + L+ LED+ A + +
Sbjct: 272 AQKDSKRIQKEYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEE- 330
Query: 202 VPAQRKADLDEEMIVLLKRRDVAENLNKKLQFCHQRLQI---ISQALSSW 248
AQ+ EEM+V K+R++ E +K Q +R ++ I A+ +W
Sbjct: 331 --AQKHRQQYEEMVVQAKKRELKEAQRRKKQL-EERCRVEESIGNAVLTW 377
>gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog A
[Homo sapiens]
Length = 771
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/115 (23%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
Query: 216 VLLKRRDVAENLNKKLQFCHQRLQIISQAL----SSWVKSDMSSPFQDFVEQIQKTKYLQ 271
+LL+ + +L K+ + SQ S V S++ Q E Q K
Sbjct: 419 ILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKA 478
Query: 272 GDQGIVEELMEDDPRRAKEAEIMLHYIERFNELISLGEYEKAACYAANS-PRRIL 325
+G + ++ ++P +E ++L ER L L E K C+ PR +L
Sbjct: 479 SSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVL 533
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 31.2 bits (69), Expect = 2.8
Identities = 30/138 (21%), Positives = 60/138 (43%), Gaps = 18/138 (13%)
Query: 171 QESMNLDALTKYMKHLEDKYAEIKQAM-----------LIKYVPAQRKADLDEEMIVLLK 219
+E MN + + K ++LEDK + +K+ + K+ + +L EEM L +
Sbjct: 933 EEEMNSELVAK-KRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEE 991
Query: 220 RRDVAENLNKKLQFCHQR----LQIISQALSSWVK--SDMSSPFQDFVEQIQKTKYLQGD 273
K LQ HQ+ LQ+ ++ +K + + D +++ K L+ D
Sbjct: 992 NISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRAD 1051
Query: 274 QGIVEELMEDDPRRAKEA 291
+ +E D + ++E+
Sbjct: 1052 LERAKRKLEGDLKMSQES 1069
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 31.2 bits (69), Expect = 2.8
Identities = 34/156 (21%), Positives = 66/156 (42%), Gaps = 25/156 (16%)
Query: 61 IEHITAYKSILT----SIKKEYDAFIETIKKDRRTTFCLHGKLKG-------LAAEPTAL 109
+E + A K L ++K+E + +K+++T LH L+ LA
Sbjct: 1101 LEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIK 1160
Query: 110 VYYRKRTIQLEAKMRIIESNS-------SKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPS 162
+ K ++A +R E S SK+QS++ + KQ + +T+EV + K
Sbjct: 1161 EAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATK 1220
Query: 163 KPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAML 198
+ + +L + + +L KY E+ + +L
Sbjct: 1221 SDL-------ETQISSLNEKLANLNRKYEEVCEEVL 1249
Score = 29.6 bits (65), Expect = 8.1
Identities = 50/264 (18%), Positives = 99/264 (37%), Gaps = 43/264 (16%)
Query: 62 EHITAYKSILTSIKKEYDAFIETI---KKDRRTTFCLHGKLKGLAAEPTALVYYRK---- 114
EH S+ S++K D+ E + +K + LH ++K E + K
Sbjct: 914 EHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA 973
Query: 115 RTIQLEAKMRIIESNSSKIQSQI-----------DHIKQCRAEYDTKEVKYCTFSKDPS- 162
+ E R ++ +++ Q+ + +K+ + E D + + T KD
Sbjct: 974 PIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRD 1033
Query: 163 -----KPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQ-------------AMLIKYVPA 204
+ M S D L K +K L KY E+K + ++
Sbjct: 1034 KTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNL 1093
Query: 205 QRKADLDEEMIVLLKR--RDVAENLN---KKLQFCHQRLQIISQALSSWVKSDMSSPFQD 259
+K + E + LK+ ENL K +Q C+++ Q L +++ +S
Sbjct: 1094 LQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSV-P 1152
Query: 260 FVEQIQKTKYLQGDQGIVEELMED 283
E +Q + + + GI++ + +
Sbjct: 1153 LAEHLQIKEAFEKEVGIIKASLRE 1176
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 31.2 bits (69), Expect = 2.8
Identities = 34/156 (21%), Positives = 66/156 (42%), Gaps = 25/156 (16%)
Query: 61 IEHITAYKSILT----SIKKEYDAFIETIKKDRRTTFCLHGKLKG-------LAAEPTAL 109
+E + A K L ++K+E + +K+++T LH L+ LA
Sbjct: 1114 LEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIK 1173
Query: 110 VYYRKRTIQLEAKMRIIESNS-------SKIQSQIDHIKQCRAEYDTKEVKYCTFSKDPS 162
+ K ++A +R E S SK+QS++ + KQ + +T+EV + K
Sbjct: 1174 EAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATK 1233
Query: 163 KPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQAML 198
+ + +L + + +L KY E+ + +L
Sbjct: 1234 SDL-------ETQISSLNEKLANLNRKYEEVCEEVL 1262
Score = 29.6 bits (65), Expect = 8.1
Identities = 50/264 (18%), Positives = 99/264 (37%), Gaps = 43/264 (16%)
Query: 62 EHITAYKSILTSIKKEYDAFIETI---KKDRRTTFCLHGKLKGLAAEPTALVYYRK---- 114
EH S+ S++K D+ E + +K + LH ++K E + K
Sbjct: 927 EHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA 986
Query: 115 RTIQLEAKMRIIESNSSKIQSQI-----------DHIKQCRAEYDTKEVKYCTFSKDPS- 162
+ E R ++ +++ Q+ + +K+ + E D + + T KD
Sbjct: 987 PIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRD 1046
Query: 163 -----KPIPGMTLQESMNLDALTKYMKHLEDKYAEIKQ-------------AMLIKYVPA 204
+ M S D L K +K L KY E+K + ++
Sbjct: 1047 KTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNL 1106
Query: 205 QRKADLDEEMIVLLKR--RDVAENLN---KKLQFCHQRLQIISQALSSWVKSDMSSPFQD 259
+K + E + LK+ ENL K +Q C+++ Q L +++ +S
Sbjct: 1107 LQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSV-P 1165
Query: 260 FVEQIQKTKYLQGDQGIVEELMED 283
E +Q + + + GI++ + +
Sbjct: 1166 LAEHLQIKEAFEKEVGIIKASLRE 1189
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,433,908
Number of Sequences: 37866
Number of extensions: 843433
Number of successful extensions: 2452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2423
Number of HSP's gapped (non-prelim): 76
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.