Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 207029223

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|207029223 paired box 7 isoform 3 [Homo sapiens]
         (505 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|207029223 paired box 7 isoform 3 [Homo sapiens]                   1029   0.0  
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                      957   0.0  
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                      949   0.0  
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 745   0.0  
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 745   0.0  
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  739   0.0  
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                738   0.0  
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 620   e-177
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 620   e-177
gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]                  343   2e-94
gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]                  343   2e-94
gi|189083681 paired box gene 6 isoform a [Homo sapiens]               257   2e-68
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 257   2e-68
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 247   2e-65
gi|9951920 paired box 5 [Homo sapiens]                                219   6e-57
gi|34878716 paired box protein 2 isoform d [Homo sapiens]             213   3e-55
gi|34878701 paired box protein 2 isoform b [Homo sapiens]             213   3e-55
gi|34878709 paired box protein 2 isoform c [Homo sapiens]             213   3e-55
gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]                  206   4e-53
gi|34878699 paired box protein 2 isoform a [Homo sapiens]             204   2e-52
gi|34878703 paired box protein 2 isoform e [Homo sapiens]             204   2e-52
gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]                  201   1e-51
gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]                  200   2e-51
gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]                  200   2e-51
gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]                  200   2e-51
gi|197276661 paired box 1 [Homo sapiens]                              188   1e-47
gi|7242167 paired box 9 [Homo sapiens]                                186   3e-47
gi|170784824 paired box 4 [Homo sapiens]                              186   4e-47
gi|24497589 aristaless related homeobox [Homo sapiens]                114   2e-25
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                112   8e-25

>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 1029 bits (2661), Expect = 0.0
 Identities = 505/505 (100%), Positives = 505/505 (100%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
           YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180

Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300

Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
           PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360

Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
           YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420

Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLS 480
           ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLS
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQTAVDYLAKNVSLS 480

Query: 481 TQRRMKLGEHSAVLGLLPVETGQAY 505
           TQRRMKLGEHSAVLGLLPVETGQAY
Sbjct: 481 TQRRMKLGEHSAVLGLLPVETGQAY 505


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score =  957 bits (2475), Expect = 0.0
 Identities = 467/468 (99%), Positives = 468/468 (100%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
           YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180

Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300

Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
           PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360

Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
           YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420

Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQ+
Sbjct: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 468


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score =  949 bits (2452), Expect = 0.0
 Identities = 465/468 (99%), Positives = 466/468 (99%), Gaps = 2/468 (0%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDG 180
           YKRENPGMFSWEIRDRLLKDGHCDRSTVPS  VSSISRVLRIKFGKKEEEDEADKKEDDG
Sbjct: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPS--VSSISRVLRIKFGKKEEEDEADKKEDDG 178

Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH
Sbjct: 179 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 238

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL
Sbjct: 239 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 298

Query: 301 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 360
           PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS
Sbjct: 299 PPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSS 358

Query: 361 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 420
           YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS
Sbjct: 359 YSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSIS 418

Query: 421 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQ+
Sbjct: 419 ASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQS 466


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  745 bits (1923), Expect = 0.0
 Identities = 374/490 (76%), Positives = 416/490 (84%), Gaps = 18/490 (3%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N   VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414

Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           L GGL+  T++SASCSQR D +K  DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQ+
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474

Query: 469 AVDYLAKNVS 478
           A  YL  +++
Sbjct: 475 AFHYLKPDIA 484


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  745 bits (1923), Expect = 0.0
 Identities = 374/490 (76%), Positives = 416/490 (84%), Gaps = 18/490 (3%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N   VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414

Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           L GGL+  T++SASCSQR D +K  DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQ+
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474

Query: 469 AVDYLAKNVS 478
           A  YL  +++
Sbjct: 475 AFHYLKPDIA 484


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  739 bits (1907), Expect = 0.0
 Identities = 371/480 (77%), Positives = 410/480 (85%), Gaps = 18/480 (3%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N   VP QPQ D+++SP
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 414

Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           L GGL+  T++SASCSQR D +K  DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQ+
Sbjct: 415 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 474


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  738 bits (1906), Expect = 0.0
 Identities = 373/490 (76%), Positives = 415/490 (84%), Gaps = 19/490 (3%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+ V TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPK-VTTPDVEKKIEE 119

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 120 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 176

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 177 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 236

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 237 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 296

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 297 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 353

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGNPSAVPPQPQADFSISP 408
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQVM +L N   VP QPQ D+++SP
Sbjct: 354 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP 413

Query: 409 LHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGYQYGQYGQT 468
           L GGL+  T++SASCSQR D +K  DSLPTSQ+YCPPTYSTTGYS+DPV GYQYGQYGQ+
Sbjct: 414 LTGGLEPTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQS 473

Query: 469 AVDYLAKNVS 478
           A  YL  +++
Sbjct: 474 AFHYLKPDIA 483


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  620 bits (1598), Expect = e-177
 Identities = 316/404 (78%), Positives = 346/404 (85%), Gaps = 18/404 (4%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 392
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQV  I+ +
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  620 bits (1598), Expect = e-177
 Identities = 316/404 (78%), Positives = 346/404 (85%), Gaps = 18/404 (4%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGN--RLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKA 235
           ++ EKKAKHSIDGIL ++ +  + DEGSD++SEPDLPLKRKQRRSRTTFTAEQLEELE+A
Sbjct: 178 EESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERA 237

Query: 236 FERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPT 295
           FERTHYPDIYTREELAQR KLTEARVQVWFSNRRARWRKQAGANQL AFNHL+PGGFPPT
Sbjct: 238 FERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPT 297

Query: 296 GMPTLPPYQLPDSTYPTTTISQ---DGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAY 352
            MPTLP YQL +++Y  T+I Q   D  STVHRPQPLPPST+HQ   +   +  D+SSAY
Sbjct: 298 AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQ---STIPSNPDSSSAY 354

Query: 353 ---GARHSFSSYSDSFMNPAAPSNHMNP-VSNGLSPQVMSILGN 392
                RH FSSY+DSF+ P+ PSN MNP + NGLSPQV  I+ +
Sbjct: 355 CLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVPFIISS 398


>gi|7524356 paired box 3 isoform PAX3b [Homo sapiens]
          Length = 206

 Score =  343 bits (881), Expect = 2e-94
 Identities = 172/205 (83%), Positives = 182/205 (88%), Gaps = 6/205 (2%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGNRLDEG 202
           ++ EKKAKHSIDGIL ++G  L  G
Sbjct: 178 EESEKKAKHSIDGILSERGKALVSG 202


>gi|6654638 paired box 3 isoform PAX3a [Homo sapiens]
          Length = 215

 Score =  343 bits (880), Expect = 2e-94
 Identities = 171/201 (85%), Positives = 181/201 (90%), Gaps = 6/201 (2%)

Query: 1   MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60
           M  L G VPRMMRP PGQNYPR+GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV
Sbjct: 1   MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIV 60

Query: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEE 120
           EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKP+QV TPDVEKKIEE
Sbjct: 61  EMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEE 120

Query: 121 YKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEAD---KKE 177
           YKRENPGMFSWEIRD+LLKD  CDR+TVPS  VSSISR+LR KFGK EEE EAD   K+ 
Sbjct: 121 YKRENPGMFSWEIRDKLLKDAVCDRNTVPS--VSSISRILRSKFGKGEEE-EADLERKEA 177

Query: 178 DDGEKKAKHSIDGILGDKGNR 198
           ++ EKKAKHSIDGIL ++G R
Sbjct: 178 EESEKKAKHSIDGILSERGKR 198


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  257 bits (656), Expect = 2e-68
 Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)

Query: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67

Query: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
           P AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C    +PS  VSSI+
Sbjct: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124

Query: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180
           RVLR    +K++                                     +D   ++E  G
Sbjct: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184

Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           E     S +G          E SD E++  L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YPD++ RE LA +  L EAR+QVWFSNRRA+WR++             P   P +   + 
Sbjct: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293

Query: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359
             YQ +P  T P ++ +   GS + R                  A  +T SA     SF+
Sbjct: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336

Query: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417
             ++  M P  PS   +   + + P   S+ G    +  PP  Q   +  P+  G    T
Sbjct: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392

Query: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
           S           I PG S+P       P  S
Sbjct: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  257 bits (656), Expect = 2e-68
 Identities = 179/451 (39%), Positives = 230/451 (50%), Gaps = 83/451 (18%)

Query: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+VS+GCVSKIL RY ETGSIR
Sbjct: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIR 67

Query: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
           P AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C    +PS  VSSI+
Sbjct: 68  PRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPS--VSSIN 124

Query: 158 RVLRIKFGKKEE-------------------------------------EDEADKKEDDG 180
           RVLR    +K++                                     +D   ++E  G
Sbjct: 125 RVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGG 184

Query: 181 EKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           E     S +G          E SD E++  L LKRK +R+RT+FT EQ+E LEK FERTH
Sbjct: 185 ENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH 233

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YPD++ RE LA +  L EAR+QVWFSNRRA+WR++             P   P +   + 
Sbjct: 234 YPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFST 293

Query: 301 PPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFS 359
             YQ +P  T P ++ +   GS + R                  A  +T SA     SF+
Sbjct: 294 SVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TALTNTYSALPPMPSFT 336

Query: 360 SYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQADFSISPLHGGLDSAT 417
             ++  M P  PS   +   + + P   S+ G    +  PP  Q   +  P+  G    T
Sbjct: 337 MANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPM--GTSGTT 392

Query: 418 SISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
           S           I PG S+P       P  S
Sbjct: 393 STGL--------ISPGVSVPVQVPGSEPDMS 415


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  247 bits (631), Expect = 2e-65
 Identities = 179/465 (38%), Positives = 230/465 (49%), Gaps = 97/465 (20%)

Query: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLR--------------VSHGCV 83
           VNQLGGVF+NGRPLP+  R KIVE+AH G RPC ISR L+              VS+GCV
Sbjct: 8   VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV 67

Query: 84  SKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHC 143
           SKIL RY ETGSIRP AIGGSKPR VATP+V  KI +YKRE P +F+WEIRDRLL +G C
Sbjct: 68  SKILGRYYETGSIRPRAIGGSKPR-VATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVC 126

Query: 144 DRSTVPSGLVSSISRVLRIKFGKKEE---------------------------------- 169
               +PS  VSSI+RVLR    +K++                                  
Sbjct: 127 TNDNIPS--VSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPG 184

Query: 170 ---EDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226
              +D   ++E  GE     S +G          E SD E++  L LKRK +R+RT+FT 
Sbjct: 185 QPTQDGCQQQEGGGENTNSISSNG----------EDSD-EAQMRLQLKRKLQRNRTSFTQ 233

Query: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286
           EQ+E LEK FERTHYPD++ RE LA +  L EAR+QVWFSNRRA+WR++           
Sbjct: 234 EQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS 293

Query: 287 LLPGGFPPTGMPTLPPYQ-LPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAA 345
             P   P +   +   YQ +P  T P ++ +   GS + R                  A 
Sbjct: 294 NTPSHIPISSSFSTSVYQPIPQPTTPVSSFT--SGSMLGRTD---------------TAL 336

Query: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGN--PSAVPPQPQAD 403
            +T SA     SF+  ++  M P  PS   +   + + P   S+ G    +  PP  Q  
Sbjct: 337 TNTYSALPPMPSFTMANNLPMQPPVPSQTSS--YSCMLPTSPSVNGRSYDTYTPPHMQTH 394

Query: 404 FSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYS 448
            +  P+  G    TS           I PG S+P       P  S
Sbjct: 395 MNSQPM--GTSGTTSTGL--------ISPGVSVPVQVPGSEPDMS 429


>gi|9951920 paired box 5 [Homo sapiens]
          Length = 391

 Score =  219 bits (557), Expect = 6e-57
 Identities = 148/371 (39%), Positives = 192/371 (51%), Gaps = 43/371 (11%)

Query: 25  FPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVS 84
           +P   ++  G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVS
Sbjct: 7   YPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVS 66

Query: 85  KILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCD 144
           KIL RY ETGSI+PG IGGSKP+ VATP V +KI EYKR+NP MF+WEIRDRLL +  CD
Sbjct: 67  KILGRYYETGSIKPGVIGGSKPK-VATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCD 125

Query: 145 RSTVPSGLVSSISRVLRIKFGKKEEEDEADKKE--------------DDGEKKAKHSIDG 190
             TVPS  VSSI+R++R K  +   +                           + +SI G
Sbjct: 126 NDTVPS--VSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISG 183

Query: 191 ILG-------DKGNRLDEG---SDVESEPDLP---LKRKQRRSRTTFTAEQLEELEKAFE 237
           ILG           + DEG   S V +   LP     RKQ R    FT +QLE L++ FE
Sbjct: 184 ILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRG-DLFTQQQLEVLDRVFE 242

Query: 238 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGM 297
           R HY DI+T  E  +  + TE       +      +    +   A     +PG   P   
Sbjct: 243 RQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPG---PQSY 299

Query: 298 PTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHS 357
           P +    L  +T P        G   H P P    +     L      ++ S +  +   
Sbjct: 300 PIVTGRDLASTTLP--------GYPPHVP-PAGQGSYSAPTLTGMVPGSEFSGSPYSHPQ 350

Query: 358 FSSYSDSFMNP 368
           +SSY+DS+  P
Sbjct: 351 YSSYNDSWRFP 361


>gi|34878716 paired box protein 2 isoform d [Homo sapiens]
          Length = 408

 Score =  213 bits (543), Expect = 3e-55
 Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132

Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
           SSI+R++R K  +                                  +    +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192

Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
                G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251

Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
           D++   E  +  +  E  +           S+  A    + G+N      + +  G    
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311

Query: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
            T +P  PP+  P    +YPT+T+      S+  G+    PQ
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353


>gi|34878701 paired box protein 2 isoform b [Homo sapiens]
          Length = 393

 Score =  213 bits (543), Expect = 3e-55
 Identities = 140/342 (40%), Positives = 183/342 (53%), Gaps = 52/342 (15%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132

Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
           SSI+R++R K  +                                  +    +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192

Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
                G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251

Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
           D++   E  +  +  E  +           S+  A    + G+N      + +  G    
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311

Query: 294 PTGMPTLPPYQLP--DSTYPTTTI------SQDGGSTVHRPQ 327
            T +P  PP+  P    +YPT+T+      S+  G+    PQ
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQ 353


>gi|34878709 paired box protein 2 isoform c [Homo sapiens]
          Length = 396

 Score =  213 bits (542), Expect = 3e-55
 Identities = 136/325 (41%), Positives = 178/325 (54%), Gaps = 46/325 (14%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132

Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGILG 193
           SSI+R++R K  +                                  +    +SI+GILG
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192

Query: 194 ---DKGNRLDEGSDV--------ESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYP 242
                G +     DV        +S+  +   RK  R+  TFT +QLE L++ FER  YP
Sbjct: 193 IPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALDRVFERPSYP 251

Query: 243 DIYTREELAQRTKLTEARVQVWF-------SNRRARWRKQAGANQLAAFNHLLPGG--FP 293
           D++   E  +  +  E  +           S+  A    + G+N      + +  G    
Sbjct: 252 DVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMA 311

Query: 294 PTGMPTLPPYQLP--DSTYPTTTIS 316
            T +P  PP+  P    +YPT+T++
Sbjct: 312 STTLPGYPPHVPPTGQGSYPTSTLA 336


>gi|7524361 paired box 8 isoform PAX8B [Homo sapiens]
          Length = 387

 Score =  206 bits (524), Expect = 4e-53
 Identities = 158/410 (38%), Positives = 199/410 (48%), Gaps = 86/410 (20%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G +NQLGG F+NGRPLP  +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9   GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 69  GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125

Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
           SSI+R++R K    F    +   A K    G                     + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185

Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           LG      DK    D   D     ++S+      RK  R+   F+   LE LE  FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YP+ Y                        +  + + G   L   N  L       G  TL
Sbjct: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278

Query: 301 PPYQLP-------DSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA------D 347
            P   P         TYP     +  G T+    P  P T  QG  A++A A        
Sbjct: 279 TPSNTPLGRNLSTHQTYPVVAGREMVGPTLPGYPPHIP-TSGQGSYASSAIAGMVAGSEY 337

Query: 348 TSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVP 397
           + +AYG    +SSYS+++  P +        S   SP   S    PSA P
Sbjct: 338 SGNAYG-HTPYSSYSEAWRFPNS--------SLLSSPYYYSSTSRPSAPP 378


>gi|34878699 paired box protein 2 isoform a [Homo sapiens]
          Length = 416

 Score =  204 bits (519), Expect = 2e-52
 Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132

Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
           SSI+R++R K  +                                  +    +SI+GIL 
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192

Query: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
                G+K  R                          + EGS  + +S+  +   RK  R
Sbjct: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252

Query: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
           +  TFT +QLE L++ FER  YPD++   E  +  +  E  +           S+  A  
Sbjct: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311

Query: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
             + G+N      + +  G     T +P  PP+  P    +YPT+T+      S+  G+ 
Sbjct: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371

Query: 323 VHRPQ 327
              PQ
Sbjct: 372 YSHPQ 376


>gi|34878703 paired box protein 2 isoform e [Homo sapiens]
          Length = 431

 Score =  204 bits (519), Expect = 2e-52
 Identities = 142/365 (38%), Positives = 187/365 (51%), Gaps = 75/365 (20%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G VNQLGGVF+NGRPLP+ +R +IVE+AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 16  GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYET 75

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSI+PG IGGSKP+ VATP V  KI EYKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 76  GSIKPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPS--V 132

Query: 154 SSISRVLRIKFGKK--------------------EEEDEADKKEDDGEKKAKHSIDGIL- 192
           SSI+R++R K  +                                  +    +SI+GIL 
Sbjct: 133 SSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILG 192

Query: 193 -----GDKGNR--------------------------LDEGS--DVESEPDLPLKRKQRR 219
                G+K  R                          + EGS  + +S+  +   RK  R
Sbjct: 193 IPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLR 252

Query: 220 SRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWF-------SNRRARW 272
           +  TFT +QLE L++ FER  YPD++   E  +  +  E  +           S+  A  
Sbjct: 253 A-DTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSAST 311

Query: 273 RKQAGANQLAAFNHLLPGG--FPPTGMPTLPPYQLP--DSTYPTTTI------SQDGGST 322
             + G+N      + +  G     T +P  PP+  P    +YPT+T+      S+  G+ 
Sbjct: 312 NPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNP 371

Query: 323 VHRPQ 327
              PQ
Sbjct: 372 YSHPQ 376


>gi|7524363 paired box 8 isoform PAX8C [Homo sapiens]
          Length = 398

 Score =  201 bits (512), Expect = 1e-51
 Identities = 155/415 (37%), Positives = 196/415 (47%), Gaps = 86/415 (20%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G +NQLGG F+NGRPLP  +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9   GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 69  GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125

Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
           SSI+R++R K    F    +   A K    G                     + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185

Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           LG      DK    D   D     ++S+      RK  R+   F+   LE LE  FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244

Query: 241 YPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTL 300
           YP+ Y                        +  + + G   L   N  L       G  TL
Sbjct: 245 YPEAYASP---------------------SHTKGEQGLYPLPLLNSTL-----DDGKATL 278

Query: 301 PPYQLP-------DSTYPTTTI-------SQDGGSTVHRPQP-LPPSTMHQGGLAAAAAA 345
            P   P         TYP               GS    P P LPP T    G + A  +
Sbjct: 279 TPSNTPLGRNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCT----GSSRARPS 334

Query: 346 ADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNPSAVPPQP 400
           +     +G R   +  +    +P A    M P+ +    Q ++ L  P A PP P
Sbjct: 335 SQGERWWGPRCPDTHPT----SPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTP 385


>gi|7524365 paired box 8 isoform PAX8D [Homo sapiens]
          Length = 321

 Score =  200 bits (509), Expect = 2e-51
 Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G +NQLGG F+NGRPLP  +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9   GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 69  GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125

Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
           SSI+R++R K    F    +   A K    G                     + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185

Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           LG      DK    D   D     ++S+      RK  R+   F+   LE LE  FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244

Query: 241 YPDIY 245
           YP+ Y
Sbjct: 245 YPEAY 249


>gi|7669542 paired box 8 isoform PAX8E [Homo sapiens]
          Length = 287

 Score =  200 bits (509), Expect = 2e-51
 Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G +NQLGG F+NGRPLP  +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9   GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 69  GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125

Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
           SSI+R++R K    F    +   A K    G                     + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185

Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           LG      DK    D   D     ++S+      RK  R+   F+   LE LE  FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244

Query: 241 YPDIY 245
           YP+ Y
Sbjct: 245 YPEAY 249


>gi|5803117 paired box 8 isoform PAX8A [Homo sapiens]
          Length = 450

 Score =  200 bits (509), Expect = 2e-51
 Identities = 120/245 (48%), Positives = 147/245 (60%), Gaps = 37/245 (15%)

Query: 34  GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQET 93
           G G +NQLGG F+NGRPLP  +R +IV++AH G+RPC ISRQLRVSHGCVSKIL RY ET
Sbjct: 9   GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYET 68

Query: 94  GSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153
           GSIRPG IGGSKP+ VATP V +KI +YKR+NP MF+WEIRDRLL +G CD  TVPS  V
Sbjct: 69  GSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPS--V 125

Query: 154 SSISRVLRIK----FGKKEEEDEADKKEDDGEK------------------KAKHSIDGI 191
           SSI+R++R K    F    +   A K    G                     + +SI+G+
Sbjct: 126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGL 185

Query: 192 LG------DKGNRLDEGSD-----VESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTH 240
           LG      DK    D   D     ++S+      RK  R+   F+   LE LE  FER H
Sbjct: 186 LGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DAFSQHHLEPLECPFERQH 244

Query: 241 YPDIY 245
           YP+ Y
Sbjct: 245 YPEAY 249


>gi|197276661 paired box 1 [Homo sapiens]
          Length = 534

 Score =  188 bits (477), Expect = 1e-47
 Identities = 103/162 (63%), Positives = 120/162 (74%), Gaps = 9/162 (5%)

Query: 8   VPRMMRPAPGQNYPRTGFPLEVSTPLGQ----GRVNQLGGVFINGRPLPNHIRHKIVEMA 63
           +P    P+PG  +P      +++ PL      G VNQLGGVF+NGRPLPN IR +IVE+A
Sbjct: 70  LPDCAGPSPG--HPGHPGARQLAGPLAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELA 127

Query: 64  HHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKR 123
             GIRPC ISRQLRVSHGCVSKIL RY ETGSI PGAIGGSKPR V TP+V K I +YK+
Sbjct: 128 QLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPR-VTTPNVVKHIRDYKQ 186

Query: 124 ENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFG 165
            +PG+F+WEIRDRLL DG CD+  VPS  VSSISR+LR K G
Sbjct: 187 GDPGIFAWEIRDRLLADGVCDKYNVPS--VSSISRILRNKIG 226


>gi|7242167 paired box 9 [Homo sapiens]
          Length = 341

 Score =  186 bits (473), Expect = 3e-47
 Identities = 97/139 (69%), Positives = 108/139 (77%), Gaps = 3/139 (2%)

Query: 36  GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGS 95
           G VNQLGGVF+NGRPLPN IR +IVE+A  GIRPC ISRQLRVSHGCVSKIL RY ETGS
Sbjct: 6   GEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGS 65

Query: 96  IRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSS 155
           I PGAIGGSKPR V TP V K I  YK+ +PG+F+WEIRDRLL DG CD+  VPS  VSS
Sbjct: 66  ILPGAIGGSKPR-VTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPS--VSS 122

Query: 156 ISRVLRIKFGKKEEEDEAD 174
           ISR+LR K G   ++   D
Sbjct: 123 ISRILRNKIGNLAQQGHYD 141


>gi|170784824 paired box 4 [Homo sapiens]
          Length = 343

 Score =  186 bits (472), Expect = 4e-47
 Identities = 128/327 (39%), Positives = 167/327 (51%), Gaps = 45/327 (13%)

Query: 38  VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIR 97
           +NQLGG+F+NGRPLP   R +IV +A  G+RPC ISR L+VS+GCVSKIL RY  TG + 
Sbjct: 1   MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE 60

Query: 98  PGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSIS 157
           P  IGGSKPR +ATP V  +I + K E P +F+WEI+ +L  +G C +   PS  VSSI+
Sbjct: 61  PKGIGGSKPR-LATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS--VSSIN 117

Query: 158 RVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQ 217
           RVLR              +ED G    +     +L         GS+    P        
Sbjct: 118 RVLRA------------LQEDQGLPCTRLRSPAVLAPAVLTPHSGSET---PRGTHPGTG 162

Query: 218 RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ-- 275
            R+RT F+  Q E LEK F+R  YPD   R +LA  T L E  V+VWFSNRRA+WR+Q  
Sbjct: 163 HRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEK 222

Query: 276 -------AGANQLAAFNHLL---------PGGFPPTGMPTLPP-----YQLPDSTYPTTT 314
                   GA+Q      +          PG  P   +P L P     YQL  +T P   
Sbjct: 223 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERC 282

Query: 315 ISQDGGSTVHRP----QPLPPSTMHQG 337
           +S        +P     P  P+++  G
Sbjct: 283 LSDTPPKACLKPCWGHLPPQPNSLDSG 309


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score =  114 bits (285), Expect = 2e-25
 Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)

Query: 189 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 248
           +G  G+    L  GSD  SE  L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359

Query: 249 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 308
           ELA R  LTEARVQVWF NRRA+WRK+  A    A  H       P G+P   P     +
Sbjct: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406

Query: 309 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
           T+P +          H P       +     AAAAAAA
Sbjct: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score =  112 bits (280), Expect = 8e-25
 Identities = 68/192 (35%), Positives = 101/192 (52%), Gaps = 13/192 (6%)

Query: 214 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 273
           K K+RR+RTTF+  QLEELEK F++THYPD+Y RE+LA RT LTEARVQVWF NRRA+WR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209

Query: 274 KQAGANQLAAFNHLLPGGFPPTGMPTLPPY-QLPDSTYPTTTISQDGGSTVHRPQPLP-- 330
           K+    ++    +     +  + +P    + QL +S + +      GG  +  P+ +P  
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSP 269

Query: 331 ---PSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNG--LSPQ 385
              P +   G +A        S+A+   +S   +      P    +   P S+G   SP 
Sbjct: 270 CMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFP-----PTLGGHSFEPSSDGDYKSPS 324

Query: 386 VMSILGNPSAVP 397
           ++S+   P   P
Sbjct: 325 LVSLRVKPKEPP 336


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,950,160
Number of Sequences: 37866
Number of extensions: 1242321
Number of successful extensions: 6236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 5338
Number of HSP's gapped (non-prelim): 1010
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press