Search of human proteins with 206725454

Search of human proteins with 206725454

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
         (394 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is...   802   0.0  
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso...   390   e-109
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   104   2e-22
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ...   104   2e-22
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al...   104   2e-22
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a...   103   3e-22
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b...   103   4e-22
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g...   100   2e-21
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...   100   2e-21
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,...    99   7e-21
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,...    99   7e-21
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,...    99   7e-21
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ...    94   2e-19
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,...    82   8e-16
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    62   1e-09
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ...    35   0.12 
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ...    35   0.12 
gi|224994173 roundabout 1 isoform d [Homo sapiens]                     35   0.15 
gi|224994171 roundabout 1 isoform c [Homo sapiens]                     35   0.15 
gi|19743806 roundabout 1 isoform b [Homo sapiens]                      35   0.15 
gi|4506569 roundabout 1 isoform a [Homo sapiens]                       35   0.15 
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ...    30   3.8  
gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ...    30   3.8  
gi|5032105 small optic lobes [Homo sapiens]                            30   4.9  
gi|13489095 sialoadhesin precursor [Homo sapiens]                      29   6.5  
gi|210147600 tripartite motif-containing 64 [Homo sapiens]             29   8.4  
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...    29   8.4  
gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo sa...    29   8.4  
gi|150170699 kinesin family member 26A [Homo sapiens]                  29   8.4  
gi|95147559 ankyrin repeat domain 43 [Homo sapiens]                    29   8.4  

>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score =  802 bits (2072), Expect = 0.0
 Identities = 394/394 (100%), Positives = 394/394 (100%)

Query: 1   MAAPSPGPREVLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMTCMMQ 60
           MAAPSPGPREVLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMTCMMQ
Sbjct: 1   MAAPSPGPREVLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMTCMMQ 60

Query: 61  AGLWAATQVSMDHPPTGPPSRDDFSEVLTQVHEGFELGTLAGPAFAWLRRSLGLAEEDYQ 120
           AGLWAATQVSMDHPPTGPPSRDDFSEVLTQVHEGFELGTLAGPAFAWLRRSLGLAEEDYQ
Sbjct: 61  AGLWAATQVSMDHPPTGPPSRDDFSEVLTQVHEGFELGTLAGPAFAWLRRSLGLAEEDYQ 120

Query: 121 AALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHS 180
           AALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHS
Sbjct: 121 AALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHS 180

Query: 181 LLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVL 240
           LLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVL
Sbjct: 181 LLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVL 240

Query: 241 VLKDLNFQGKTINLGPQRSWFLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSL 300
           VLKDLNFQGKTINLGPQRSWFLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSL
Sbjct: 241 VLKDLNFQGKTINLGPQRSWFLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSL 300

Query: 301 IFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLE 360
           IFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLE
Sbjct: 301 IFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLE 360

Query: 361 HLWKTLRYPGRTFSTVSPARYARRLCQWVEAHTE 394
           HLWKTLRYPGRTFSTVSPARYARRLCQWVEAHTE
Sbjct: 361 HLWKTLRYPGRTFSTVSPARYARRLCQWVEAHTE 394


>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
           isoform 2 [Homo sapiens]
          Length = 191

 Score =  390 bits (1003), Expect = e-109
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 204 MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKTINLGPQRSWFLR 263
           MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKTINLGPQRSWFLR
Sbjct: 1   MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKTINLGPQRSWFLR 60

Query: 264 QMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRR 323
           QMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRR
Sbjct: 61  QMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRR 120

Query: 324 LLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPARYAR 383
           LLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPARYAR
Sbjct: 121 LLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPARYAR 180

Query: 384 RLCQWVEAHTE 394
           RLCQWVEAHTE
Sbjct: 181 RLCQWVEAHTE 191


>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 1 [Homo sapiens]
          Length = 562

 Score =  104 bits (259), Expect = 2e-22
 Identities = 85/322 (26%), Positives = 143/322 (44%), Gaps = 34/322 (10%)

Query: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H    F   T A  AF + R   G+  +DY  +L    P ++  S+  S + F++S
Sbjct: 128 LTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-SEPLIELCSSGASGSLFYVS 186

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 187 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAG-GKNIRIVVMN 245

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           ++   + ++  +YD+KG    R         PL    KDL+F      G  ++     + 
Sbjct: 246 NLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA- 303

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSS---------------LIFRTA 305
             + ++ D   L+   ++DYSLL++   +   +R P SS                ++ TA
Sbjct: 304 LCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTA 363

Query: 306 -RSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQR--YFLGVVDLATVYGLRKRLEHL 362
             S+QG     E+R        D    +   +   +R   ++G++D+   Y   K+LEH 
Sbjct: 364 MESIQG-----EARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHS 418

Query: 363 WKTLRYPGRTFSTVSPARYARR 384
           WK L + G T S   P  YA R
Sbjct: 419 WKALVHDGDTVSVHRPGFYAER 440


>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 4 [Homo sapiens]
          Length = 500

 Score =  104 bits (259), Expect = 2e-22
 Identities = 85/322 (26%), Positives = 143/322 (44%), Gaps = 34/322 (10%)

Query: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H    F   T A  AF + R   G+  +DY  +L    P ++  S+  S + F++S
Sbjct: 115 LTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-SEPLIELCSSGASGSLFYVS 173

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 174 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAG-GKNIRIVVMN 232

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           ++   + ++  +YD+KG    R         PL    KDL+F      G  ++     + 
Sbjct: 233 NLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA- 290

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSS---------------LIFRTA 305
             + ++ D   L+   ++DYSLL++   +   +R P SS                ++ TA
Sbjct: 291 LCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTA 350

Query: 306 -RSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQR--YFLGVVDLATVYGLRKRLEHL 362
             S+QG     E+R        D    +   +   +R   ++G++D+   Y   K+LEH 
Sbjct: 351 MESIQG-----EARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHS 405

Query: 363 WKTLRYPGRTFSTVSPARYARR 384
           WK L + G T S   P  YA R
Sbjct: 406 WKALVHDGDTVSVHRPGFYAER 427


>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
           isoform 2 [Homo sapiens]
          Length = 549

 Score =  104 bits (259), Expect = 2e-22
 Identities = 85/322 (26%), Positives = 143/322 (44%), Gaps = 34/322 (10%)

Query: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H    F   T A  AF + R   G+  +DY  +L    P ++  S+  S + F++S
Sbjct: 115 LTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-SEPLIELCSSGASGSLFYVS 173

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 174 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAG-GKNIRIVVMN 232

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           ++   + ++  +YD+KG    R         PL    KDL+F      G  ++     + 
Sbjct: 233 NLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA- 290

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSS---------------LIFRTA 305
             + ++ D   L+   ++DYSLL++   +   +R P SS                ++ TA
Sbjct: 291 LCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTA 350

Query: 306 -RSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQR--YFLGVVDLATVYGLRKRLEHL 362
             S+QG     E+R        D    +   +   +R   ++G++D+   Y   K+LEH 
Sbjct: 351 MESIQG-----EARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHS 405

Query: 363 WKTLRYPGRTFSTVSPARYARR 384
           WK L + G T S   P  YA R
Sbjct: 406 WKALVHDGDTVSVHRPGFYAER 427


>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
           alpha [Homo sapiens]
          Length = 406

 Score =  103 bits (257), Expect = 3e-22
 Identities = 87/313 (27%), Positives = 150/313 (47%), Gaps = 37/313 (11%)

Query: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
           F  LR   G+ ++D+Q +L    P L   S ++S A F  S+D+R+ +KT    +V  + 
Sbjct: 98  FRNLRERFGIDDQDFQNSLTRSAP-LPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMH 156

Query: 165 AHLPRYVQHL-QRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
             L +Y Q++ + H  +LL + LG++ L VD G + Y IV ++VF     +  +YD+KG 
Sbjct: 157 NILKKYHQYIVECHGITLLPQFLGMYRLNVD-GVEIYVIVTRNVFSHRLSVYRKYDLKGS 215

Query: 224 EVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
            V+R      +   L   LKD +F  +G+ I +    +  FL +++ D  FL +L ++DY
Sbjct: 216 TVAREASDKEKAKELP-TLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDY 274

Query: 281 SLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAP-NAL------- 332
           SLL+    +H+ ER     +         G +  E          PD+P N L       
Sbjct: 275 SLLVG---IHDVERAEQEEV---ECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLA 328

Query: 333 ---------------HILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFSTV 376
                          H     ++ YF+ ++D+ T Y  +K+  H  KT+++  G   STV
Sbjct: 329 PGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTV 388

Query: 377 SPARYARRLCQWV 389
           +P +Y++R   ++
Sbjct: 389 NPEQYSKRFLDFI 401


>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
           [Homo sapiens]
          Length = 416

 Score =  103 bits (256), Expect = 4e-22
 Identities = 84/320 (26%), Positives = 155/320 (48%), Gaps = 46/320 (14%)

Query: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
           F  LR   G+ ++DYQ ++    P +   S  +    F  ++D+RF +KT    +V  + 
Sbjct: 103 FRNLRERFGIDDQDYQNSVTRSAP-INSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMH 161

Query: 165 AHLPRYVQHL-QRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
             L +Y Q + + H ++LL + LG++ L VD G +TY +V ++VF     +  +YD+KG 
Sbjct: 162 NILKKYHQFIVECHGNTLLPQFLGMYRLTVD-GVETYMVVTRNVFSHRLTVHRKYDLKGS 220

Query: 224 EVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
            V+R      +   L    KD +F  +G+ +++G + +  FL +++ D  FL +L ++DY
Sbjct: 221 TVAREASDKEKAKDLP-TFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDY 279

Query: 281 SLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPE-ESRAQNRRLL------PDAPNAL- 332
           SLL+    +H+ +R     +        + A+  E E+      LL      PD+P  L 
Sbjct: 280 SLLVG---IHDVDRAEQEEM-----EVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLL 331

Query: 333 ----------------------HILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRY-P 369
                                 H     ++ YF+ ++D+ T Y  +K+  H  KT+++  
Sbjct: 332 SFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGA 391

Query: 370 GRTFSTVSPARYARRLCQWV 389
           G   STV+P +Y++R  +++
Sbjct: 392 GAEISTVNPEQYSKRFNEFM 411


>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
           gamma [Homo sapiens]
          Length = 668

 Score =  100 bits (250), Expect = 2e-21
 Identities = 85/327 (25%), Positives = 149/327 (45%), Gaps = 34/327 (10%)

Query: 88  LTQVH--EGFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H  + F   T A  AF + R   G+  +DY  +L    P ++  +   S + F+++
Sbjct: 122 LTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-NEPLIELSNPGASGSLFYVT 180

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 181 SDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQ-SGGKNIRVVVMN 239

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           ++     ++  ++D+KG    R      E        KDL+F     +G  ++     S 
Sbjct: 240 NILPRVVKMHLKFDLKGSTYKRRASKK-EKEKSFPTYKDLDFMQDMPEGLLLD-ADTFSA 297

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRL--HE------------DERGP-GSSLIFRTA 305
            ++ ++ D   L    ++DYSLL+    +  HE            DE+ P G   ++ TA
Sbjct: 298 LVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTA 357

Query: 306 -RSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFL--GVVDLATVYGLRKRLEHL 362
             S+QG  +  E+   +     D    +  ++G  +R  L  G++D+   Y   K+LEH 
Sbjct: 358 MESIQGGAARGEAIESD-----DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHT 412

Query: 363 WKTLRYPGRTFSTVSPARYARRLCQWV 389
           WK L + G T S   P+ YA R  +++
Sbjct: 413 WKALVHDGDTVSVHRPSFYAERFFKFM 439


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score =  100 bits (249), Expect = 2e-21
 Identities = 85/328 (25%), Positives = 146/328 (44%), Gaps = 30/328 (9%)

Query: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H    F   T A  AF + R   G+  +DY  ++    P ++  +   S + FF++
Sbjct: 72  LTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSIC-SEPLIELSNPGASGSLFFVT 130

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   G     +VM 
Sbjct: 131 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQ-SGGINIRIVVMN 189

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           +V   + R+   YD+KG    R      E        KDL+F     +G   +     + 
Sbjct: 190 NVLPRSMRMHFTYDLKGSTYKRRAS-RKEREKSNPTFKDLDFLQDMHEGLYFDTETYNA- 247

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAF---------------QRLHEDERGPGSSLIFRTA 305
            ++ ++ D   L    ++DYSLL+                 Q + + +R     +++ TA
Sbjct: 248 LMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTA 307

Query: 306 -RSVQG-AQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLW 363
             S+QG  +S +    +N   +   P   H   G +   F+G++D+   Y L K+LEH W
Sbjct: 308 MESIQGPGKSGDGIITENPDTMGGIPAKSH--RGEKLLLFMGIIDILQSYRLMKKLEHSW 365

Query: 364 KTLRYPGRTFSTVSPARYARRLCQWVEA 391
           K L Y G T S   P+ YA R  +++ +
Sbjct: 366 KALVYDGDTVSVHRPSFYADRFLKFMNS 393


>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform b [Homo sapiens]
          Length = 403

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)

Query: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
           F  LR   G+ ++DY  +L    P      +  S   F +S+D+   +K     ++  + 
Sbjct: 90  FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 145

Query: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
           ++L  Y Q++ + H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG 
Sbjct: 146 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 204

Query: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
            VSR      +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DY
Sbjct: 205 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263

Query: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326
           SLL+                 R  E E     SL    A       SPE          P
Sbjct: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323

Query: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374
             P          A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   S
Sbjct: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383

Query: 375 TVSPARYARRLCQWV 389
           TV P +YA+R   ++
Sbjct: 384 TVHPEQYAKRFLDFI 398


>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)

Query: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
           F  LR   G+ ++DY  +L    P      +  S   F +S+D+   +K     ++  + 
Sbjct: 108 FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 163

Query: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
           ++L  Y Q++ + H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG 
Sbjct: 164 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 222

Query: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
            VSR      +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DY
Sbjct: 223 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 281

Query: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326
           SLL+                 R  E E     SL    A       SPE          P
Sbjct: 282 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 341

Query: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374
             P          A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   S
Sbjct: 342 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 401

Query: 375 TVSPARYARRLCQWV 389
           TV P +YA+R   ++
Sbjct: 402 TVHPEQYAKRFLDFI 416


>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform a [Homo sapiens]
          Length = 421

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)

Query: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
           F  LR   G+ ++DY  +L    P      +  S   F +S+D+   +K     ++  + 
Sbjct: 108 FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 163

Query: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
           ++L  Y Q++ + H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG 
Sbjct: 164 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 222

Query: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
            VSR      +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DY
Sbjct: 223 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 281

Query: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326
           SLL+                 R  E E     SL    A       SPE          P
Sbjct: 282 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 341

Query: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374
             P          A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   S
Sbjct: 342 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 401

Query: 375 TVSPARYARRLCQWV 389
           TV P +YA+R   ++
Sbjct: 402 TVHPEQYAKRFLDFI 416


>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
           alpha isoform 3 [Homo sapiens]
          Length = 522

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 83/304 (27%), Positives = 134/304 (44%), Gaps = 26/304 (8%)

Query: 88  LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
           LT  H    F   T A  AF + R   G+  +DY  +L    P ++  S+  S + F++S
Sbjct: 116 LTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC-SEPLIELCSSGASGSLFYVS 174

Query: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
            D  F +KT   +E + L   LP Y  +L ++P +LL +  G++ ++   GK    +VM 
Sbjct: 175 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAG-GKNIRIVVMN 233

Query: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
           ++   + ++  +YD+KG    R         PL    KDL+F      G  ++     + 
Sbjct: 234 NLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLP-TFKDLDFLQDIPDGLFLDADMYNA- 291

Query: 261 FLRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPEESRAQ 320
             + ++ D   L+   ++DYSLL++   +   +R P SS    T  SV   + P   +A 
Sbjct: 292 LCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSS---ETQYSVD-TRRPAPQKAL 347

Query: 321 NRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPAR 380
                     A+  + G  +R      D   V    K+LEH WK L + G T S   P  
Sbjct: 348 -------YSTAMESIQGEARRGGTMETDDQFV----KKLEHSWKALVHDGDTVSVHRPGF 396

Query: 381 YARR 384
           YA R
Sbjct: 397 YAER 400


>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
           gamma isoform c [Homo sapiens]
          Length = 373

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 69/249 (27%), Positives = 117/249 (46%), Gaps = 31/249 (12%)

Query: 170 YVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWV 229
           Y+  ++ H ++LL + LG++ + VD  + +Y +VM+++F     +  +YD+KG  VSR  
Sbjct: 122 YLYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREA 180

Query: 230 DPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDYSLLIAF 286
               +   L   LKD++F  K   + +G + +  FL +++ D  FL +L ++DYSLL+  
Sbjct: 181 SDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGI 239

Query: 287 Q--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAPN-- 330
                          R  E E     SL    A       SPE          P  P   
Sbjct: 240 HDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEF 299

Query: 331 -------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFSTVSPAR 380
                  A+   +G  Q+  YF+G++D+ T Y  +K+  H  KT+++  G   STV P +
Sbjct: 300 ESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQ 359

Query: 381 YARRLCQWV 389
           YA+R   ++
Sbjct: 360 YAKRFLDFI 368


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 54/187 (28%), Positives = 95/187 (50%), Gaps = 17/187 (9%)

Query: 112  LGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYV 171
            L  +EED+  +L    P+       KS A+F+ + D RF LK   R EVQ+ L   P Y 
Sbjct: 1838 LDSSEEDFIRSLSHSSPWQA--RGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYF 1895

Query: 172  QHL----QRHPHSLLARLLGVHSL-----RVDRGKKTYFIVMQSVFYPAGRISERYDIKG 222
             ++    Q+   + LA++LGV+ +     + +  KK   +VM+++FY   ++++ +D+KG
Sbjct: 1896 NYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFY-GRKMAQVFDLKG 1954

Query: 223  CEVSRWV--DPAPEGSPLVLVLKDL--NFQGKTINLGPQRSWFLR-QMELDTTFLRELNV 277
               +R V  D   E   +VL+ ++L    +   + +       LR  +  D+ FL    +
Sbjct: 1955 SLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLI 2014

Query: 278  LDYSLLI 284
            +DYSLL+
Sbjct: 2015 IDYSLLV 2021


>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
            sapiens]
          Length = 1562

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1100 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARTYLQQDELEEEEDER------GPTPP 1153

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1154 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1200


>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
            sapiens]
          Length = 1615

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1153 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARTYLQQDELEEEEDER------GPTPP 1206

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1207 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1253


>gi|224994173 roundabout 1 isoform d [Homo sapiens]
          Length = 1551

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1089 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDER------GPTPP 1142

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1143 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1189


>gi|224994171 roundabout 1 isoform c [Homo sapiens]
          Length = 1606

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1144 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDER------GPTPP 1197

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1198 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1244


>gi|19743806 roundabout 1 isoform b [Homo sapiens]
          Length = 1612

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1150 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDER------GPTPP 1203

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1204 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1250


>gi|4506569 roundabout 1 isoform a [Homo sapiens]
          Length = 1651

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 8/107 (7%)

Query: 74   PPTGPPSRDDFSEVLTQVHEGF--ELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQ 131
            PP  PP   +  E    V E +  E+     PA  +L++     EED +      GP   
Sbjct: 1189 PPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDER------GPTPP 1242

Query: 132  FLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQRHP 178
                + S A+   SH     L    + E+Q +L   P    H+Q  P
Sbjct: 1243 VRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQP 1289


>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
           sapiens]
          Length = 800

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 3/29 (10%)

Query: 6   PGPREVLAPSPEAGC---RAVTSSRRGLL 31
           PG R+ L+P PE  C   R V S R GLL
Sbjct: 483 PGARDALSPDPERPCPGTRGVRSGREGLL 511


>gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo
           sapiens]
          Length = 488

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 3/29 (10%)

Query: 6   PGPREVLAPSPEAGC---RAVTSSRRGLL 31
           PG R+ L+P PE  C   R V S R GLL
Sbjct: 355 PGARDALSPDPERPCPGTRGVRSGREGLL 383


>gi|5032105 small optic lobes [Homo sapiens]
          Length = 1086

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 12  LAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGL----FEISPGHELHGMTCMMQAGLWA-A 66
           + P  EAGC   + ++R  LW    +++   L    F +  G  + G+  +  A   + A
Sbjct: 601 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA 660

Query: 67  TQVSMDHPPTGPPSRD-DFSEVLTQVHEGFELGTLAG 102
            Q+S  +P   P   D  ++++L+    GF +G   G
Sbjct: 661 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCG 697


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 289 LHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVD 348
           LHE   GPGSSL+   A S         +R  +    P +P  L +L  P Q  F   +D
Sbjct: 552 LHE---GPGSSLLLPAASSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLD 608

Query: 349 L 349
           L
Sbjct: 609 L 609


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 13/37 (35%), Positives = 22/37 (59%)

Query: 140 ASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQR 176
           A+F +  D+RFFL +  R    +L  + P  +Q++QR
Sbjct: 365 ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQR 401


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 13/37 (35%), Positives = 22/37 (59%)

Query: 140 ASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHLQR 176
           A+F +  D+RFFL +  R    +L  + P  +Q++QR
Sbjct: 365 ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQR 401


>gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo
           sapiens]
          Length = 258

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 11/110 (10%)

Query: 249 GKT-INLGPQRSWFLRQ------MELDTTFLRELNV----LDYSLLIAFQRLHEDERGPG 297
           GKT + L  QR   +RQ      +E+D  F+  +N+         ++AF +  E   GP 
Sbjct: 144 GKTAMLLALQRDMAVRQHLLTNLVEVDGRFVWRVNLDALTQHLDKILAFPQRQESYLGPT 203

Query: 298 SSLIFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVV 347
             L+   ++ V  +  PE  R   R  +   PNA H +     + F+  +
Sbjct: 204 LFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFIAAI 253


>gi|150170699 kinesin family member 26A [Homo sapiens]
          Length = 1882

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 3/87 (3%)

Query: 4    PSPGPREVLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMT---CMMQ 60
            P  GPR      P  G +A   +  G    LR   SR+     S      G +       
Sbjct: 1530 PVAGPRAAPRAGPSVGAKAGRGTVMGTKQALRAAHSRVHELSASGAPGRGGSSWGSADSD 1589

Query: 61   AGLWAATQVSMDHPPTGPPSRDDFSEV 87
            +G  +   V  + PPTGP     +S+V
Sbjct: 1590 SGHDSGVNVGEERPPTGPALPSPYSKV 1616


>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
          Length = 549

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 230 DPAPEGSPLVLVLKDLNFQGKTINLGPQRSWFLRQM 265
           +P+P  SPL+L    +   G  + LGP RS  LR++
Sbjct: 246 EPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRL 281


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,289,085
Number of Sequences: 37866
Number of extensions: 795881
Number of successful extensions: 1894
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1840
Number of HSP's gapped (non-prelim): 34
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.