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Search of human proteins with 20631964
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20631964 BCL2-associated X protein isoform delta [Homo
sapiens]
(143 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens] 295 1e-80
gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens] 271 1e-73
gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens] 233 4e-62
gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens] 203 3e-53
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens] 61 3e-10
gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens] 61 4e-10
gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens] 58 3e-09
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 56 1e-08
gi|4757842 BCL2-like 2 protein [Homo sapiens] 55 2e-08
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 53 1e-07
gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo sap... 48 2e-06
gi|14210524 BCL2-related ovarian killer [Homo sapiens] 47 5e-06
gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo ... 46 9e-06
gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens] 45 2e-05
gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens] 39 0.001
gi|195947374 claudin 5 [Homo sapiens] 31 0.31
gi|195947372 claudin 5 [Homo sapiens] 31 0.31
gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens] 30 0.53
gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens] 30 0.53
gi|183979973 claudin 19 isoform a [Homo sapiens] 27 4.4
gi|183979975 claudin 19 isoform b [Homo sapiens] 27 4.4
gi|100913021 BCL2-like 12 isoform 3 [Homo sapiens] 27 5.8
gi|20336330 BCL2-like 12 isoform 1 [Homo sapiens] 27 5.8
>gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens]
Length = 143
Score = 295 bits (754), Expect = 1e-80
Identities = 143/143 (100%), Positives = 143/143 (100%)
Query: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGMIAAVDTDSPREVFFRVAADMFSDGNFNWGR 60
MDGSGEQPRGGGPTSSEQIMKTGALLLQGMIAAVDTDSPREVFFRVAADMFSDGNFNWGR
Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGMIAAVDTDSPREVFFRVAADMFSDGNFNWGR 60
Query: 61 VVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPT 120
VVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPT
Sbjct: 61 VVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPT 120
Query: 121 WQTVTIFVAGVLTASLTIWKKMG 143
WQTVTIFVAGVLTASLTIWKKMG
Sbjct: 121 WQTVTIFVAGVLTASLTIWKKMG 143
>gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]
Length = 192
Score = 271 bits (694), Expect = 1e-73
Identities = 143/192 (74%), Positives = 143/192 (74%), Gaps = 49/192 (25%)
Query: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQG------------------------------- 29
MDGSGEQPRGGGPTSSEQIMKTGALLLQG
Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
Query: 30 ------------------MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 71
MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
Query: 72 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 131
VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 180
Query: 132 LTASLTIWKKMG 143
LTASLTIWKKMG
Sbjct: 181 LTASLTIWKKMG 192
>gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens]
Length = 179
Score = 233 bits (594), Expect = 4e-62
Identities = 130/192 (67%), Positives = 130/192 (67%), Gaps = 62/192 (32%)
Query: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQG------------------------------- 29
MDGSGEQPRGGGPTSSEQIMKTGALLLQG
Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
Query: 30 ------------------MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 71
MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
Query: 72 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV 131
VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW TVTIFVAGV
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW-------------TVTIFVAGV 167
Query: 132 LTASLTIWKKMG 143
LTASLTIWKKMG
Sbjct: 168 LTASLTIWKKMG 179
>gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]
Length = 218
Score = 203 bits (517), Expect = 3e-53
Identities = 111/162 (68%), Positives = 111/162 (68%), Gaps = 49/162 (30%)
Query: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQG------------------------------- 29
MDGSGEQPRGGGPTSSEQIMKTGALLLQG
Sbjct: 1 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS 60
Query: 30 ------------------MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 71
MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
Sbjct: 61 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL 120
Query: 72 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLL 113
VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW LL
Sbjct: 121 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLL 162
>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
Length = 239
Score = 61.2 bits (147), Expect = 3e-10
Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 43 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGW 102
F V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L W
Sbjct: 130 FATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTW 188
Query: 103 IQDQGGWDGLLSYFG 117
IQD GGWD + +G
Sbjct: 189 IQDNGGWDAFVELYG 203
>gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]
Length = 233
Score = 60.8 bits (146), Expect = 4e-10
Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Query: 43 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGW 102
F +V ++F DG NWGR+VA F F L ++++ ++ L+ I W +L + L W
Sbjct: 123 FEQVVNELFRDG-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPW 181
Query: 103 IQDQGGWDGLLSYFG 117
IQ+ GGWD + +G
Sbjct: 182 IQENGGWDTFVELYG 196
>gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]
Length = 205
Score = 57.8 bits (138), Expect = 3e-09
Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 43 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGW 102
F V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L W
Sbjct: 130 FATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTW 188
Query: 103 IQDQGGWDGLL 113
IQD GGW G L
Sbjct: 189 IQDNGGWVGAL 199
>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
Length = 175
Score = 55.8 bits (133), Expect = 1e-08
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 15/147 (10%)
Query: 10 GGGPTSSEQIMKTGALLLQGMIA-----------AVDTDSPREVFFRVAADMFSDGNFNW 58
G GP+ + ++++ A +Q + V D+ R +F +V F DG NW
Sbjct: 27 GSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINW 86
Query: 59 GRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRERLLGWIQDQGGWD-GLLS 114
GR+V +F F L+ K L ++ + + I + +F+ WI+ GGW+ G +
Sbjct: 87 GRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVK 146
Query: 115 YFGTPTWQTVTIFVAGVLTASLTIWKK 141
F + + V G + L++ K+
Sbjct: 147 KFEPKSGWMTFLEVTGKICEMLSLLKQ 173
>gi|4757842 BCL2-like 2 protein [Homo sapiens]
Length = 193
Score = 55.1 bits (131), Expect = 2e-08
Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 34 VDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLD 93
V S ++ F +V+ ++F G NWGR+VA F F + L +++ ++ L+ + W +
Sbjct: 70 VTPGSAQQRFTQVSDELFQGGP-NWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVA 128
Query: 94 FLRERLLGWIQDQGGWDGLLSYFG 117
+L RL WI GGW + +G
Sbjct: 129 YLETRLADWIHSSGGWAEFTALYG 152
>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
Length = 163
Score = 52.8 bits (125), Expect = 1e-07
Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 10 GGGPTSSEQIMKTGALLLQGMIA-----------AVDTDSPREVFFRVAADMFSDGNFNW 58
G GP+ + ++++ A +Q + V D+ R +F +V F DG NW
Sbjct: 27 GSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINW 86
Query: 59 GRVVALFYFASKLVLKALCTKVP---ELIRTIMGWTLDFLRERLLGWIQDQGGW 109
GR+V +F F L+ K L ++ + + I + +F+ WI+ GGW
Sbjct: 87 GRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGW 140
>gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo
sapiens]
Length = 350
Score = 48.1 bits (113), Expect = 2e-06
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 28 QGMIAAVDTDSPREV--FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIR 85
QGM+ +D + +V RV +FSDG NWGR+V L F + + I
Sbjct: 229 QGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIE 288
Query: 86 TIMGWTLDFLRERLLGWIQDQGGWDGLLSYF 116
+ D L W+ Q GWDG + +F
Sbjct: 289 PLAESITDVLVRTKRDWLVKQRGWDGFVEFF 319
>gi|14210524 BCL2-related ovarian killer [Homo sapiens]
Length = 212
Score = 47.0 bits (110), Expect = 5e-06
Identities = 22/73 (30%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 41 EVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLL 100
+ F VA +FS G WG+VV+L+ A+ L + + P ++ ++ +F+R+ L
Sbjct: 104 DAFLAVAGHIFSAG-ITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLA 162
Query: 101 GWIQDQGGWDGLL 113
W++ +GGW +L
Sbjct: 163 TWLRRRGGWTDVL 175
>gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo
sapiens]
Length = 211
Score = 46.2 bits (108), Expect = 9e-06
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 41 EVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLL 100
E F ++A+ +F G NWGRVVAL F+ +L L + + + + +DF+ +
Sbjct: 109 EYFTKIASSLFESG-INWGRVVALLGFSYRLALHIYQRGLTGFLGQVTRFVVDFMLHHCI 167
Query: 101 G-WIQDQGGWDGLLSYFGTPTWQTVTI 126
WI +GGW L+ P + +
Sbjct: 168 ARWIAQRGGWVAALNLGNGPILNVLVV 194
>gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens]
Length = 211
Score = 45.4 bits (106), Expect = 2e-05
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 41 EVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLL 100
E F ++A +F G NWGRVVAL F +L L + + + + +DF+ +
Sbjct: 109 EYFTKIATSLFESG-INWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCI 167
Query: 101 G-WIQDQGGWDGLLSYFGTPTWQTVTI 126
WI +GGW L+ P + +
Sbjct: 168 ARWIAQRGGWVAALNLGNGPILNVLVV 194
>gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens]
Length = 204
Score = 39.3 bits (90), Expect = 0.001
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 25/110 (22%)
Query: 58 WGRVVALFYFASKLVLKALCTKV--------PELIRTIMGWTLD------FLRERLLG-- 101
WGRVV L FA L+ + P L D L RL+G
Sbjct: 94 WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153
Query: 102 --WIQDQGGWDGLLSYFGTP----TW--QTVTIFVAGVL-TASLTIWKKM 142
W+Q QGGWDG +F TP W Q V F++ +L TA + +W ++
Sbjct: 154 RAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRL 203
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 31.2 bits (69), Expect = 0.31
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 99 LLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWK 140
+LG + GW GL+ G P WQ VT F+ + + T WK
Sbjct: 93 ILGLVLCLVGWGGLILACGLPMWQ-VTAFLDHNIVTAQTTWK 133
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 31.2 bits (69), Expect = 0.31
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 99 LLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWK 140
+LG + GW GL+ G P WQ VT F+ + + T WK
Sbjct: 93 ILGLVLCLVGWGGLILACGLPMWQ-VTAFLDHNIVTAQTTWK 133
>gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]
Length = 327
Score = 30.4 bits (67), Expect = 0.53
Identities = 10/27 (37%), Positives = 17/27 (62%)
Query: 87 IMGWTLDFLRERLLGWIQDQGGWDGLL 113
++G+ +L+E WIQ GGW+ +L
Sbjct: 293 VLGFGTKYLKENFSPWIQQHGGWEKIL 319
>gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]
Length = 327
Score = 30.4 bits (67), Expect = 0.53
Identities = 10/27 (37%), Positives = 17/27 (62%)
Query: 87 IMGWTLDFLRERLLGWIQDQGGWDGLL 113
++G+ +L+E WIQ GGW+ +L
Sbjct: 293 VLGFGTKYLKENFSPWIQQHGGWEKIL 319
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 27.3 bits (59), Expect = 4.4
Identities = 11/37 (29%), Positives = 20/37 (54%)
Query: 98 RLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTA 134
+LLG+ GGW G+++ P W+ + ++TA
Sbjct: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITA 43
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 27.3 bits (59), Expect = 4.4
Identities = 11/37 (29%), Positives = 20/37 (54%)
Query: 98 RLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTA 134
+LLG+ GGW G+++ P W+ + ++TA
Sbjct: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITA 43
>gi|100913021 BCL2-like 12 isoform 3 [Homo sapiens]
Length = 333
Score = 26.9 bits (58), Expect = 5.8
Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 76 LCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLS 114
L +V L T+ G +++ + WIQ GGW+G+L+
Sbjct: 285 LSRRVAGLGGTLAGLSVEHVHS-FTPWIQAHGGWEGILA 322
>gi|20336330 BCL2-like 12 isoform 1 [Homo sapiens]
Length = 334
Score = 26.9 bits (58), Expect = 5.8
Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 76 LCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLS 114
L +V L T+ G +++ + WIQ GGW+G+L+
Sbjct: 286 LSRRVAGLGGTLAGLSVEHVHS-FTPWIQAHGGWEGILA 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,391,182
Number of Sequences: 37866
Number of extensions: 205283
Number of successful extensions: 391
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 358
Number of HSP's gapped (non-prelim): 27
length of query: 143
length of database: 18,247,518
effective HSP length: 92
effective length of query: 51
effective length of database: 14,763,846
effective search space: 752956146
effective search space used: 752956146
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.