Guide to the Human Genome
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Search of human proteins with 20270243

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20270243 nuclear undecaprenyl pyrophosphate synthase 1
homolog [Homo sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20270243 nuclear undecaprenyl pyrophosphate synthase 1 homolo...   608   e-174
gi|45580738 dehydrodolichyl diphosphate synthase isoform b [Homo...    35   0.10 
gi|45580742 dehydrodolichyl diphosphate synthase isoform a [Homo...    35   0.10 
gi|224589135 RGM domain family, member B [Homo sapiens]                34   0.17 
gi|144922725 general transcription factor IIE, polypeptide 1, al...    32   0.87 
gi|157671915 guanylate binding protein family, member 6 [Homo sa...    29   4.3  
gi|4506449 RNA binding motif, single stranded interacting protei...    29   4.3  
gi|116256483 calcium binding atopy-related autoantigen 1 [Homo s...    29   4.3  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    29   5.6  
gi|239756243 PREDICTED: similar to hCG2038990 [Homo sapiens]           28   7.3  
gi|22027648 lipin 1 [Homo sapiens]                                     28   7.3  
gi|4506143 neurotrypsin precursor [Homo sapiens]                       28   7.3  
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              28   7.3  
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...    28   9.6  
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...    28   9.6  
gi|239755146 PREDICTED: hypothetical protein [Homo sapiens]            28   9.6  
gi|239749627 PREDICTED: hypothetical protein XP_002347107 [Homo ...    28   9.6  
gi|239743902 PREDICTED: hypothetical protein XP_002342970 [Homo ...    28   9.6  
gi|4504333 histidine ammonia-lyase [Homo sapiens]                      28   9.6  
gi|191252801 WDFY family member 4 [Homo sapiens]                       28   9.6  

>gi|20270243 nuclear undecaprenyl pyrophosphate synthase 1 homolog
           [Homo sapiens]
          Length = 293

 Score =  608 bits (1567), Expect = e-174
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPP 60
           MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPP
Sbjct: 1   MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPP 60

Query: 61  AVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASL 120
           AVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASL
Sbjct: 61  AVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASL 120

Query: 121 VVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQ 180
           VVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQ
Sbjct: 121 VVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQ 180

Query: 181 VLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDL 240
           VLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDL
Sbjct: 181 VLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDL 240

Query: 241 VLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 293
           VLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK
Sbjct: 241 VLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK 293


>gi|45580738 dehydrodolichyl diphosphate synthase isoform b [Homo
           sapiens]
          Length = 333

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 31/180 (17%)

Query: 114 FSDIASLVVWCMAVGISYISVYDHQ-GIFKRNNS--------------RLMDEILKQQQE 158
           F+ +A  + WC+ +GI  ++VY      FKR+ S              RLM+E  K Q+ 
Sbjct: 55  FNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKH 114

Query: 159 -----------LLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDF 207
                      LL LD  +   +   +    ++   C L   V      + +I  A ++ 
Sbjct: 115 GVCIRVLGDLHLLPLDLQELIAQAVQATKNYNK---CFL--NVCFAYTSRHEISNAVREM 169

Query: 208 CQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLP 267
              V Q    P+D+    L   L +N  P PD++++         FL W    + +V  P
Sbjct: 170 AWGVEQGLLDPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQP 229


>gi|45580742 dehydrodolichyl diphosphate synthase isoform a [Homo
           sapiens]
          Length = 334

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 31/180 (17%)

Query: 114 FSDIASLVVWCMAVGISYISVYDHQ-GIFKRNNS--------------RLMDEILKQQQE 158
           F+ +A  + WC+ +GI  ++VY      FKR+ S              RLM+E  K Q+ 
Sbjct: 55  FNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKH 114

Query: 159 -----------LLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDF 207
                      LL LD  +   +   +    ++   C L   V      + +I  A ++ 
Sbjct: 115 GVCIRVLGDLHLLPLDLQELIAQAVQATKNYNK---CFL--NVCFAYTSRHEISNAVREM 169

Query: 208 CQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLP 267
              V Q    P+D+    L   L +N  P PD++++         FL W    + +V  P
Sbjct: 170 AWGVEQGLLDPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQP 229


>gi|224589135 RGM domain family, member B [Homo sapiens]
          Length = 478

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 19/37 (51%), Positives = 22/37 (59%), Gaps = 4/37 (10%)

Query: 261 TEIVSLPSHLNISYEDFFS----ALRQYAACEQRLGK 293
           T+ VSL SHLN + + F S    ALR YA C QR  K
Sbjct: 102 TDFVSLTSHLNSAVDGFDSEFCKALRAYAGCTQRTSK 138


>gi|144922725 general transcription factor IIE, polypeptide 1, alpha
           56kDa [Homo sapiens]
          Length = 439

 Score = 31.6 bits (70), Expect = 0.87
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 60  PAVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQE 111
           PA+ +++ H     G + LA  HHR  W   G S E L     +VI   +QE
Sbjct: 212 PALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDL-YTQNVVINMDDQE 262


>gi|157671915 guanylate binding protein family, member 6 [Homo
           sapiens]
          Length = 633

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 4/58 (6%)

Query: 187 AVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKF 244
           AV  L+  +  A + RAA  + Q +AQ+ K PT    DTL  LL  +   + + +  F
Sbjct: 314 AVITLAQRENSAAVQRAADYYSQQMAQRVKLPT----DTLQELLDMHAACEREAIAIF 367


>gi|4506449 RNA binding motif, single stranded interacting protein 2
           [Homo sapiens]
          Length = 407

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 132 ISVYDHQGI----FKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLA 187
           +SV    GI    + RNN +     +   Q++     S  +P  ++ ++ +DQ+   +L 
Sbjct: 3   LSVTSRPGISTFGYNRNNKK---PYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLY 59

Query: 188 VKVLSPEDGKADIVRAAQDFCQLVAQK 214
           ++ L P     D+V+  Q + ++V+ K
Sbjct: 60  IRGLQPGTTDQDLVKLCQPYGKIVSTK 86


>gi|116256483 calcium binding atopy-related autoantigen 1 [Homo
           sapiens]
          Length = 478

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 13/46 (28%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 179 DQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVD 224
           D++      +KV+S E G+A++    +DF + +   +K+P  L +D
Sbjct: 125 DKIFRYFATLKVIS-EPGEAEVFMTPEDFVRSITPNEKQPEHLGLD 169


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 1/118 (0%)

Query: 106  TEVEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCS 165
            ++ E E S  +  SL      +  +Y    +H   FKR N  L +EI    ++L     +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522

Query: 166  KYSPEFANSN-DKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLD 222
             +  E      + +   L   L     S E  +  I+RA  +F Q+ A+ +++  + D
Sbjct: 1523 IHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580


>gi|239756243 PREDICTED: similar to hCG2038990 [Homo sapiens]
          Length = 185

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 11/52 (21%)

Query: 3   GLYELVWRVLHALLCLHRTLTSWLRVRFGTWNW-------IWRRCCRAASAA 47
           G+ + VW  +H  LC  R    WLR   G   W       +  R CRAA+ A
Sbjct: 123 GVLDSVWPGIHGALCAGR----WLRTSSGLHCWAHLPGSRLLARHCRAATPA 170


>gi|22027648 lipin 1 [Homo sapiens]
          Length = 890

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 7/73 (9%)

Query: 171 FANSNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLL 230
           F    D D +V+  HLA   +  E        A++  CQL      R   LD  T A ++
Sbjct: 88  FVQETDNDQEVIPMHLATSPILSEG-------ASRMECQLKRGSVDRMRGLDPSTPAQVI 140

Query: 231 SSNGCPDPDLVLK 243
           + +  P    V+K
Sbjct: 141 APSETPSSSSVVK 153


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 116 DIASLVVWCMAVGISYISVYDHQGIFKRNNSRLM-DEILKQQQELLGLDCSKYSPEFANS 174
           D A   V C  +G+S I+   HQ  F   +  +M DE+     EL    C K S    N 
Sbjct: 310 DDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNC 369

Query: 175 NDKDDQVLNC 184
             K+D  ++C
Sbjct: 370 GHKEDAGVSC 379


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 11/66 (16%)

Query: 138  QGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQV---LNC-HLAVKVLSP 193
            Q I K ++S    E++++ +       SK    F + N   DQ+   +NC H+AVK L P
Sbjct: 2331 QVIIKASSSLASSELMRKIK-------SKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEP 2383

Query: 194  EDGKAD 199
             + KAD
Sbjct: 2384 GNCKAD 2389


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 5/58 (8%)

Query: 102 GLVITEVEQEPSFSDIASLVVWCMAVG-ISYISVYDHQGIFKRNNSRLMDEILKQQQE 158
           G V  EV  +  +S      V C ++G I+YI +  +   +  N+S+L ++ILK + E
Sbjct: 186 GYVAPEVLAQKPYSK----AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 5/58 (8%)

Query: 102 GLVITEVEQEPSFSDIASLVVWCMAVG-ISYISVYDHQGIFKRNNSRLMDEILKQQQE 158
           G V  EV  +  +S      V C ++G I+YI +  +   +  N+S+L ++ILK + E
Sbjct: 186 GYVAPEVLAQKPYSK----AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239


>gi|239755146 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 115

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 18/57 (31%), Positives = 22/57 (38%), Gaps = 3/57 (5%)

Query: 38 RRCCRAASAAVLAPLGFTLRK---PPAVGRNRRHHRHPRGGSCLAAAHHRMRWRADG 91
          R   RA       P  +  R+   PPA+   RR  R P  G        R+ WRA G
Sbjct: 28 RLSARAGQPGATEPPPYRDRRSHSPPALSAPRRSGRWPSLGGLRERGRRRLDWRASG 84


>gi|239749627 PREDICTED: hypothetical protein XP_002347107 [Homo
          sapiens]
          Length = 115

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 18/57 (31%), Positives = 22/57 (38%), Gaps = 3/57 (5%)

Query: 38 RRCCRAASAAVLAPLGFTLRK---PPAVGRNRRHHRHPRGGSCLAAAHHRMRWRADG 91
          R   RA       P  +  R+   PPA+   RR  R P  G        R+ WRA G
Sbjct: 28 RLSARAGQPGATEPPPYRDRRSHSPPALSAPRRSGRWPSLGGLRERGRRRLDWRASG 84


>gi|239743902 PREDICTED: hypothetical protein XP_002342970 [Homo
          sapiens]
          Length = 115

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 18/57 (31%), Positives = 22/57 (38%), Gaps = 3/57 (5%)

Query: 38 RRCCRAASAAVLAPLGFTLRK---PPAVGRNRRHHRHPRGGSCLAAAHHRMRWRADG 91
          R   RA       P  +  R+   PPA+   RR  R P  G        R+ WRA G
Sbjct: 28 RLSARAGQPGATEPPPYRDRRSHSPPALSAPRRSGRWPSLGGLRERGRRRLDWRASG 84


>gi|4504333 histidine ammonia-lyase [Homo sapiens]
          Length = 657

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 6/66 (9%)

Query: 140 IFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLAV------KVLSP 193
           +  +  S +  E LKQ  E+    C  Y PE        D     HLA+      K+ SP
Sbjct: 217 VLAKGYSGISLETLKQVIEMFNASCLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSP 276

Query: 194 EDGKAD 199
           + G AD
Sbjct: 277 KSGWAD 282


>gi|191252801 WDFY family member 4 [Homo sapiens]
          Length = 3184

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 11/32 (34%), Positives = 18/32 (56%)

Query: 105 ITEVEQEPSFSDIASLVVWCMAVGISYISVYD 136
           +T+ E +P   ++  LVVW    G S + V+D
Sbjct: 328 LTQSEVDPHLEELLGLVVWLTTCGRSELKVFD 359


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,966,434
Number of Sequences: 37866
Number of extensions: 542133
Number of successful extensions: 1590
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1584
Number of HSP's gapped (non-prelim): 20
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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