Search of human proteins with 20070125

Search of human proteins with 20070125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
         (508 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...  1023   0.0  
gi|94966757 protein disulfide isomerase A2 [Homo sapiens]             468   e-132
gi|28372543 protein disulfide isomerase-like, testis expressed [...   278   8e-75
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]              260   2e-69
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]   253   2e-67
gi|22748703 endoplasmic reticulum protein 27 kDa [Homo sapiens]       127   3e-29
gi|5031973 protein disulfide isomerase A6 [Homo sapiens]               98   2e-20
gi|38505222 thioredoxin domain containing 10 [Homo sapiens]            94   2e-19
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    87   5e-17
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    86   6e-17
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap...    86   6e-17
gi|5803121 protein disulfide isomerase A5 [Homo sapiens]               77   5e-14
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]           64   4e-10
gi|21361403 thioredoxin 2 precursor [Homo sapiens]                     61   3e-09
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s...    60   4e-09
gi|151101292 thioredoxin domain containing 1 [Homo sapiens]            60   4e-09
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap...    58   2e-08
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap...    58   2e-08
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]          52   2e-06
gi|50592994 thioredoxin [Homo sapiens]                                 49   8e-06
gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo sa...    47   3e-05
gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo sa...    47   3e-05
gi|227430327 calsequestrin 1 [Homo sapiens]                            45   1e-04
gi|54633317 thioredoxin domain containing 11 [Homo sapiens]            45   1e-04
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap...    44   5e-04
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap...    44   5e-04
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi...    44   5e-04
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    42   0.002
gi|95113651 glutaredoxin 3 [Homo sapiens]                              40   0.004
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa...    40   0.007

>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 1023 bits (2645), Expect = 0.0
 Identities = 508/508 (100%), Positives = 508/508 (100%)

Query: 1   MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA 60
           MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA
Sbjct: 1   MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALA 60

Query: 61  PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR 120
           PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR
Sbjct: 61  PEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGR 120

Query: 121 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID 180
           EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID
Sbjct: 121 EADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID 180

Query: 181 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF 240
           DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF
Sbjct: 181 DIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEF 240

Query: 241 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR 300
           TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR
Sbjct: 241 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR 300

Query: 301 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL 360
           ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL
Sbjct: 301 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL 360

Query: 361 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI 420
           PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI
Sbjct: 361 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI 420

Query: 421 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD 480
           VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD
Sbjct: 421 VIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGD 480

Query: 481 DDDLEDLEEAEEPDMEEDDDQKAVKDEL 508
           DDDLEDLEEAEEPDMEEDDDQKAVKDEL
Sbjct: 481 DDDLEDLEEAEEPDMEEDDDQKAVKDEL 508


>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
          Length = 525

 Score =  468 bits (1204), Expect = e-132
 Identities = 234/468 (50%), Positives = 319/468 (68%), Gaps = 15/468 (3%)

Query: 18  DAPEEE----DHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAE 73
           + PEEE    D +LVL +     AL  H  LLVEFYAPWCGHC+ALAPEY+KAA  L AE
Sbjct: 32  EPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAE 91

Query: 74  GSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRT 133
              + LAKVD   + +LA+++GV  YPT+KFFRNG+   P+EYT  R+A+ I  WL++R 
Sbjct: 92  SMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRV 151

Query: 134 GPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVF 193
           GP+A  L D AAA++L+   ++ VIGFF+D++ +    FL  A+   D+ FG+T    +F
Sbjct: 152 GPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLF 211

Query: 194 SKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLD------FIKHNQLPLVIEFTEQTAPK 247
            ++ L KD VVLFKKFDEGR +F   V +E  LD      F+  + + LV EF  QT+ K
Sbjct: 212 QQFGLTKDTVVLFKKFDEGRADFP--VDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAK 269

Query: 248 IFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGL 307
           IF   I  H+LLF+ ++++ +   L+ F  AA  F+G++LF+ +D    DN+ +L++FGL
Sbjct: 270 IFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVA-ADNEHVLQYFGL 328

Query: 308 KKEECPAVRLITLEEEMTKYKP-ESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDK 366
           K E  P +RL+ LE    KY P +   +TA  IT FCH  L G++KP+L+SQE+P DWD+
Sbjct: 329 KAEAAPTLRLVNLETTK-KYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQ 387

Query: 367 QPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMD 426
           +PVK LVGKNFE VAFDE KNVFV+FYAPWC HCK++AP W+ L E Y+DHE+I+IA++D
Sbjct: 388 RPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELD 447

Query: 427 STANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGG 474
           +TANE++A  VH FPTLK+FPA   R VI+Y   R L+ F KFL++GG
Sbjct: 448 ATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGG 495


>gi|28372543 protein disulfide isomerase-like, testis expressed
           [Homo sapiens]
          Length = 584

 Score =  278 bits (711), Expect = 8e-75
 Identities = 156/485 (32%), Positives = 262/485 (54%), Gaps = 4/485 (0%)

Query: 22  EEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAK 81
           EE  +LVL  +   + L   ++L+V F+ P     + LA E  KA   +    + I   K
Sbjct: 41  EERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGK 100

Query: 82  VDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLP 141
           VD T E +L Q++G+   P +K F  G+ + P       E+  +V WL+++    A    
Sbjct: 101 VDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFN 160

Query: 142 DGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKD 201
                   V S  + ++GFF+D+E + A+ F    +   ++ FG+ +  +V  ++ +  D
Sbjct: 161 SSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLD 220

Query: 202 GVVLFKK--FDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILL 259
            V++FKK      +        K+ L   IK +    VIE+  +    I    I +H+LL
Sbjct: 221 SVLVFKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLL 280

Query: 260 FLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLIT 319
           F+ KS   Y   + ++K A++ F+ KILFI +D+D   N R+ ++F + + + P+V+++ 
Sbjct: 281 FVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILN 340

Query: 320 LEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFED 379
           L  +  +YK  S+++T E + +F   FL      H  S+E+P+ WD+  VK LVGKNF  
Sbjct: 341 LSSD-ARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNV 399

Query: 380 VAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHS 439
           V FD++K+VFV FYAPW   CK L P+ ++LG  Y++H  I+IAK+D TAN+++ + +  
Sbjct: 400 VVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDR 459

Query: 440 FPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDD 499
           +P  + FP+ + + V+ Y GE TL GF  FLES  +    D+D+L  +E+ E  + E   
Sbjct: 460 YPFFRLFPSGSQQAVL-YKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLA 518

Query: 500 DQKAV 504
           ++K V
Sbjct: 519 EEKEV 523


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score =  260 bits (665), Expect = 2e-69
 Identities = 167/467 (35%), Positives = 252/467 (53%), Gaps = 36/467 (7%)

Query: 27  LVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATE 86
           LVL K NF E +     +LVEFYAPWCGHCK LAPEY KAA +L      I LAKVDAT 
Sbjct: 180 LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATA 239

Query: 87  ESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG-PAATTLPDGAA 145
           E+DLA+++ V GYPT+K FR G    P +Y   RE   IV+++ +++G P+   L     
Sbjct: 240 ETDLAKRFDVSGYPTLKIFRKG---RPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQV 296

Query: 146 AESLVESSEVAVIGFFKDVESDSAKQFLQAAEAI-DDIPFGITSNSDVFSKYQLDKDGVV 204
            E L +  +V +IG FK     + +Q+  AA  + +D  F  T ++++    ++ +  +V
Sbjct: 297 QEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLV 356

Query: 205 L-----FKKFDEGRNNF---EGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTH 256
           +     F+   E R++    +G      + DF+    LPLV         K +       
Sbjct: 357 VMQPEKFQSKYEPRSHMMDVQGSTQDSAIKDFVLKYALPLVGHRKVSNDAKRYTRR---- 412

Query: 257 ILLFLPKSVSDYDGKLS-NFKTAAESFKGKIL--------FIFIDSDHTDNQRILEFFGL 307
                P  V  Y    S +++ A + ++ K+L        + F  +D  D    ++  GL
Sbjct: 413 -----PLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGL 467

Query: 308 KKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQ 367
             E    V    L+E   K+  E EE  ++ + EF   F +GK+KP + SQ +P++ +K 
Sbjct: 468 -SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKN-NKG 525

Query: 368 PVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS 427
           PVKV+VGK F+ +  D KK+V +EFYAPWCGHCKQL P+++ L + YK  + +VIAKMD+
Sbjct: 526 PVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDA 585

Query: 428 TANEV--EAVKVHSFPTLKFFPASADRTVIDY-NGERTLDGFKKFLE 471
           TAN+V  +  KV  FPT+ F P+   +  + +  G+R L+   KF+E
Sbjct: 586 TANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIE 632



 Score =  111 bits (277), Expect = 2e-24
 Identities = 95/360 (26%), Positives = 165/360 (45%), Gaps = 42/360 (11%)

Query: 21  EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLA 80
           +EE+ VLVL  +NF   +A    +L+EFYAPWCGHCK  APEY K A  LK +   I +A
Sbjct: 59  KEENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVA 118

Query: 81  KVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTL 140
           K+DAT  S LA ++ V GYPTIK  + G      +Y   R  ++IV  +++ + P  T  
Sbjct: 119 KIDATSASVLASRFDVSGYPTIKILKKGQAV---DYEGSRTQEEIVAKVREVSQPDWTPP 175

Query: 141 PDGAAA------ESLVESSEVAVIGFF-------KDVESDSAKQFLQAAEAIDDIPFG-- 185
           P+          + +V  +++ ++ F+       K +  +  K   + ++    IP    
Sbjct: 176 PEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235

Query: 186 -ITSNSDVFSKYQLDKDGVVLFKKFDEGR-NNFEGEVTKENLLDFIKHNQLPLVIEFTEQ 243
             T+ +D+  ++  D  G    K F +GR  ++ G   K  ++D++     P   E    
Sbjct: 236 DATAETDLAKRF--DVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTL 293

Query: 244 TAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILE 303
              + F  +    I++ + K  S  D     ++ AA + +    F      HT +  I +
Sbjct: 294 KQVQEFLKDGDDVIIIGVFKGES--DPAYQQYQDAANNLREDYKF-----HHTFSTEIAK 346

Query: 304 FFGLKKEECPAVRLITLEEE--MTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELP 361
           F  + + +     L+ ++ E   +KY+P S  +  +  T+      +  IK  ++   LP
Sbjct: 347 FLKVSQGQ-----LVVMQPEKFQSKYEPRSHMMDVQGSTQ------DSAIKDFVLKYALP 395



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 41/101 (40%), Positives = 58/101 (57%), Gaps = 7/101 (6%)

Query: 365 DKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NIVIA 423
           ++  V VL   NF++   D K  V +EFYAPWCGHCKQ AP ++K+    KD +  I +A
Sbjct: 60  EENGVLVLNDANFDNFVAD-KDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVA 118

Query: 424 KMDSTANEVEAVK--VHSFPTLKFFPASADRTVIDYNGERT 462
           K+D+T+  V A +  V  +PT+K          +DY G RT
Sbjct: 119 KIDATSASVLASRFDVSGYPTIKILKKG---QAVDYEGSRT 156



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 47/114 (41%), Positives = 61/114 (53%), Gaps = 11/114 (9%)

Query: 363 DWDKQP--VKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLG-ETYKDHEN 419
           DW   P    VL  +NF++V  D    + VEFYAPWCGHCK+LAP ++K   E  K    
Sbjct: 171 DWTPPPEVTLVLTKENFDEVVNDADI-ILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPP 229

Query: 420 IVIAKMDSTANEVEAVK---VHSFPTLKFFPASADRTVIDYNGERTLDGFKKFL 470
           I +AK+D+TA E +  K   V  +PTLK F         DYNG R   G   ++
Sbjct: 230 IPLAKVDATA-ETDLAKRFDVSGYPTLKIFRKGRP---YDYNGPREKYGIVDYM 279



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 14/37 (37%), Positives = 23/37 (62%)

Query: 471 ESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDE 507
           E   +D +  ++ +ED EE EE D +E++D   VK+E
Sbjct: 25  EGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEE 61


>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
          Length = 505

 Score =  253 bits (647), Expect = 2e-67
 Identities = 167/496 (33%), Positives = 257/496 (51%), Gaps = 43/496 (8%)

Query: 2   LRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHCKA 58
           LRR  L   VA L+ A        VL L   NF   ++   +   +LVEF+APWCGHCK 
Sbjct: 3   LRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKR 62

Query: 59  LAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTA 118
           LAPEY  AA +LK     + LAKVD T  ++   +YGV GYPT+K FR+G+ A    Y  
Sbjct: 63  LAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDG 117

Query: 119 GREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEA 178
            R AD IV+ LKK+ GPA+  L      +  +   + +++GFF D  S++  +FL+AA  
Sbjct: 118 PRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASN 177

Query: 179 I-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDFIK 230
           + D+  F  T+   + ++Y  + +G++LF+      KF++    + E ++T   +  FI+
Sbjct: 178 LRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQ 237

Query: 231 HNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFI- 289
            N   +    TE     I G ++           ++ YD         +  ++ +++ + 
Sbjct: 238 ENIFGICPHMTEDNKDLIQGKDLL----------IAYYDVDYEKNAKGSNYWRNRVMMVA 287

Query: 290 --FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESEELTA 336
             F+D+ H  N  +         L  FGL+    E P V + T + E    + E      
Sbjct: 288 KKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSR-DG 346

Query: 337 ERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPW 396
           + +  F   + +G +K +L S+ +PE  D  PVKV+V +NF+++  +E K+V +EFYAPW
Sbjct: 347 KALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEFYAPW 405

Query: 397 CGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASADRTVI 455
           CGHCK L P + +LGE      NIVIAKMD+TAN+V +  +V  FPT+ F PA+      
Sbjct: 406 CGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPK 465

Query: 456 DYNGERTLDGFKKFLE 471
            Y G R L  F  +L+
Sbjct: 466 KYEGGRELSDFISYLQ 481



 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 49/114 (42%), Positives = 70/114 (61%), Gaps = 4/114 (3%)

Query: 20  PEEEDH-VLVLRKSNFAEALA-AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEI 77
           PE  D  V V+   NF E +   +K +L+EFYAPWCGHCK L P+Y +   KL  + + I
Sbjct: 371 PESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN-I 429

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKK 131
            +AK+DAT  +D+   Y VRG+PTI F       +PK+Y  GRE  D +++L++
Sbjct: 430 VIAKMDATA-NDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQR 482


>gi|22748703 endoplasmic reticulum protein 27 kDa [Homo sapiens]
          Length = 273

 Score =  127 bits (318), Expect = 3e-29
 Identities = 75/231 (32%), Positives = 125/231 (54%), Gaps = 11/231 (4%)

Query: 130 KKRTGPAA----TTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFG 185
           K   GP A    T L D  AA   + ++EVAVIGFF+D+E  +        +    + FG
Sbjct: 29  KSSDGPGAAQEPTWLTDVPAAMEFIAATEVAVIGFFQDLEIPAVPILHSMVQKFPGVSFG 88

Query: 186 ITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGE----VTKENLLDFIKHNQLPLVIEFT 241
           I+++S+V + Y +  + + LF+  D  + N E E    +    L  FI+ N L +V E+ 
Sbjct: 89  ISTDSEVLTHYNITGNTICLFRLVDNEQLNLEDEDIESIDATKLSRFIEINSLHMVTEYN 148

Query: 242 EQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRI 301
             T   +F   I+ H+LL + K+  +Y+  +  ++ AA+ F+GKILFI +DS   +N ++
Sbjct: 149 PVTVIGLFNSVIQIHLLLIMNKASPEYEENMHRYQKAAKLFQGKILFILVDSGMKENGKV 208

Query: 302 LEFFGLKKEECPAVRLI-TLEEEMTKYKPESEELTAERITEFCHRFLEGKI 351
           + FF LK+ + PA+ +  TL++E       + E++ E +  FC  FL GK+
Sbjct: 209 ISFFKLKESQLPALAIYQTLDDEWDTL--PTAEVSVEHVQNFCDGFLSGKL 257


>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
          Length = 440

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 50/113 (44%), Positives = 72/113 (63%), Gaps = 3/113 (2%)

Query: 16  RADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAE-G 74
           R+D+  ++D + +   S     L +    +VEFYAPWCGHCK L PE+A AA ++K +  
Sbjct: 153 RSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTK 212

Query: 75  SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVN 127
            +++LA VDAT    LA +YG+RG+PTIK F+ G+  SP +Y  GR   DIV+
Sbjct: 213 GKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGE--SPVDYDGGRTRSDIVS 263



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 47/105 (44%), Positives = 63/105 (60%), Gaps = 5/105 (4%)

Query: 24  DHVLVLRKSNF-AEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKV 82
           D V+ L  SNF  E + +    LVEFYAPWCGHC+ L PE+ KAA  LK     +++  V
Sbjct: 25  DDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALK---DVVKVGAV 81

Query: 83  DATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVN 127
           DA +   L  QYGV+G+PTIK F   +   P++Y  GR  + IV+
Sbjct: 82  DADKHHSLGGQYGVQGFPTIKIF-GSNKNRPEDYQGGRTGEAIVD 125



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 6/101 (5%)

Query: 366 KQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE--NIVIA 423
           K+ V  L   +F+    D +    VEFYAPWCGHCK L P W       K+     + +A
Sbjct: 159 KKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLA 218

Query: 424 KMDSTANEVEAVK--VHSFPTLKFFPASADRTVIDYNGERT 462
            +D+T N+V A +  +  FPT+K F      + +DY+G RT
Sbjct: 219 AVDATVNQVLASRYGIRGFPTIKIF--QKGESPVDYDGGRT 257



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 40/145 (27%), Positives = 59/145 (40%), Gaps = 19/145 (13%)

Query: 372 LVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE 431
           L   NF            VEFYAPWCGHC++L P W K     KD   +     D   + 
Sbjct: 30  LTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL 89

Query: 432 VEAVKVHSFPTLKFFPASADRTVIDYNGERT--------LDGFKKFLE----------SG 473
                V  FPT+K F ++ +R   DY G RT        L   ++ ++          S 
Sbjct: 90  GGQYGVQGFPTIKIFGSNKNRPE-DYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSS 148

Query: 474 GQDGAGDDDDLEDLEEAEEPDMEED 498
           G+ G  D    +D+ E  +   +++
Sbjct: 149 GKQGRSDSSSKKDVIELTDDSFDKN 173


>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
          Length = 454

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 55/165 (33%), Positives = 91/165 (55%), Gaps = 7/165 (4%)

Query: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104
           LV+FYAPWCGHCK L P + +   ++K+ GS +++ K+DAT  S +A ++GVRGYPTIK 
Sbjct: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104

Query: 105 FRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDV 164
            + GD A    Y   R  DDI+ +  + +G     LP     E + +   V  +  +   
Sbjct: 105 LK-GDLA--YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFV--YVGG 159

Query: 165 ESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKD--GVVLFK 207
           ES   ++++ AA  +    +  +++ +V  +Y   K+   V++FK
Sbjct: 160 ESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFK 204



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 9/97 (9%)

Query: 379 DVAFDEKKNV---FVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIVIAKMDSTANEVEA 434
           D +F E +N     V+FYAPWCGHCK+L PIW+++G   K     + + KMD+T+    A
Sbjct: 32  DESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIA 91

Query: 435 VK--VHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
            +  V  +PT+K           +Y G RT D   +F
Sbjct: 92  SEFGVRGYPTIKLLKGD---LAYNYRGPRTKDDIIEF 125


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 85/367 (23%), Positives = 160/367 (43%), Gaps = 19/367 (5%)

Query: 29  LRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAE---GSEIRLAKVDAT 85
           L   N  E L      LV FYA WC   + L P + +A+  +K E    +++  A+VD  
Sbjct: 34  LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93

Query: 86  EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAA 145
           + SD+AQ+Y +  YPT+K FRNG     +EY   R    + ++++++       + D A 
Sbjct: 94  QHSDIAQRYRISKYPTLKLFRNG-MMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152

Query: 146 AESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVL 205
             +L + S+  +IG+F+  +SD+ + F + A  + D    +++  DV    +   D ++ 
Sbjct: 153 ITTL-DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNII- 210

Query: 206 FKKFDEGRNN--FEGEVTKENL-LDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLP 262
           +K       +  + G +T  ++  ++I+   +PLV E T +   ++    +   IL  + 
Sbjct: 211 YKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMK 270

Query: 263 KSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEE 322
           +     +   +       S KG I F+  D D    +  L        +CP + + +   
Sbjct: 271 EDTESLEIFQNEVARQLISEKGTINFLHADCDKF--RHPLLHIQKTPADCPVIAIDSF-R 327

Query: 323 EMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAF 382
            M  +    + L   ++ +F      GK+  H      P+  D  P     G+  +DVA 
Sbjct: 328 HMYVFGDFKDVLIPGKLKQFVFDLHSGKL--HREFHHGPDPTDTAP-----GEQAQDVAS 380

Query: 383 DEKKNVF 389
              ++ F
Sbjct: 381 SPPESSF 387



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 390 VEFYAPWCGHCKQLAPIW----DKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
           V FYA WC   + L PI+    D + E + +   +V A++D   +    +  ++  +PTL
Sbjct: 51  VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110

Query: 444 KFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDL 487
           K F  +      +Y G+R++     ++     D   +  DL ++
Sbjct: 111 KLF-RNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEI 153


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
           [Homo sapiens]
          Length = 432

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 42/114 (36%), Positives = 69/114 (60%), Gaps = 3/114 (2%)

Query: 12  AALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLK 71
           A ++ A+   ++  VL L ++NF + +A      ++FYAPWCGHCK LAP + + + K  
Sbjct: 310 APVLAAEPEADKGTVLALTENNFDDTIA-EGITFIKFYAPWCGHCKTLAPTWEELSKKEF 368

Query: 72  AEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDI 125
              + +++A+VD T E ++  +Y VRGYPT+  FR G   S  E++ GR+ D +
Sbjct: 369 PGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVS--EHSGGRDLDSL 420



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 51/149 (34%), Positives = 78/149 (52%), Gaps = 14/149 (9%)

Query: 19  APEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSE-I 77
           APE +  +  L  SNF   +A   +  ++F+APWCGHCKALAP + + A  L  E SE +
Sbjct: 184 APELKQGLYELSASNFELHVAQGDHF-IKFFAPWCGHCKALAPTWEQLA--LGLEHSETV 240

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKR----- 132
           ++ KVD T+  +L     VRGYPT+ +FR+G      +Y   R+ + +  +++ +     
Sbjct: 241 KIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVD--QYKGKRDLESLREYVESQLQRTE 298

Query: 133 TGPAATTLPDGA---AAESLVESSEVAVI 158
           TG   T  P  A   AAE   +   V  +
Sbjct: 299 TGATETVTPSEAPVLAAEPEADKGTVLAL 327



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 6/92 (6%)

Query: 39  AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKA-EGSEIRLAKVDATEESDLAQQYGVR 97
           AAH    V F+APWCGHC+ L P +     K  + E +++ +AKVD T  SD+    GVR
Sbjct: 78  AAH---FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVR 134

Query: 98  GYPTIKFFRNGDTASPKEYTAGREADDIVNWL 129
           GYPT+K F+ G  A   +Y   R+   + NW+
Sbjct: 135 GYPTLKLFKPGQEA--VKYQGPRDFQTLENWM 164



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 42/115 (36%), Positives = 61/115 (53%), Gaps = 7/115 (6%)

Query: 365 DKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLG-ETYKDHENIVIA 423
           DK  V  L   NF+D   +     F++FYAPWCGHCK LAP W++L  + +     + IA
Sbjct: 320 DKGTVLALTENNFDDTIAEGI--TFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIA 377

Query: 424 KMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQD 476
           ++D TA  N      V  +PTL  F     + V +++G R LD   +F+ S  +D
Sbjct: 378 EVDCTAERNICSKYSVRGYPTLLLF--RGGKKVSEHSGGRDLDSLHRFVLSQAKD 430



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 6/109 (5%)

Query: 366 KQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
           KQ +  L   NFE      + + F++F+APWCGHCK LAP W++L    +  E + I K+
Sbjct: 188 KQGLYELSASNFE--LHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV 245

Query: 426 DSTANE--VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 472
           D T +       +V  +PTL +F     + V  Y G+R L+  ++++ES
Sbjct: 246 DCTQHYELCSGNQVRGYPTLLWF--RDGKKVDQYKGKRDLESLREYVES 292



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 6/86 (6%)

Query: 389 FVEFYAPWCGHCKQLAPIWDKLGETYKDHEN--IVIAKMDSTANE--VEAVKVHSFPTLK 444
           FV F+APWCGHC++L P W+ LG+ Y   E+  + +AK+D TA+     A  V  +PTLK
Sbjct: 81  FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140

Query: 445 FFPASADRTVIDYNGERTLDGFKKFL 470
            F    +   + Y G R     + ++
Sbjct: 141 LFKPGQE--AVKYQGPRDFQTLENWM 164


>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
           sapiens]
          Length = 324

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 42/114 (36%), Positives = 69/114 (60%), Gaps = 3/114 (2%)

Query: 12  AALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLK 71
           A ++ A+   ++  VL L ++NF + +A      ++FYAPWCGHCK LAP + + + K  
Sbjct: 202 APVLAAEPEADKGTVLALTENNFDDTIA-EGITFIKFYAPWCGHCKTLAPTWEELSKKEF 260

Query: 72  AEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDI 125
              + +++A+VD T E ++  +Y VRGYPT+  FR G   S  E++ GR+ D +
Sbjct: 261 PGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVS--EHSGGRDLDSL 312



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 51/149 (34%), Positives = 78/149 (52%), Gaps = 14/149 (9%)

Query: 19  APEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSE-I 77
           APE +  +  L  SNF   +A   +  ++F+APWCGHCKALAP + + A  L  E SE +
Sbjct: 76  APELKQGLYELSASNFELHVAQGDHF-IKFFAPWCGHCKALAPTWEQLA--LGLEHSETV 132

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKR----- 132
           ++ KVD T+  +L     VRGYPT+ +FR+G      +Y   R+ + +  +++ +     
Sbjct: 133 KIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVD--QYKGKRDLESLREYVESQLQRTE 190

Query: 133 TGPAATTLPDGA---AAESLVESSEVAVI 158
           TG   T  P  A   AAE   +   V  +
Sbjct: 191 TGATETVTPSEAPVLAAEPEADKGTVLAL 219



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 42/115 (36%), Positives = 61/115 (53%), Gaps = 7/115 (6%)

Query: 365 DKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLG-ETYKDHENIVIA 423
           DK  V  L   NF+D   +     F++FYAPWCGHCK LAP W++L  + +     + IA
Sbjct: 212 DKGTVLALTENNFDDTIAEGI--TFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIA 269

Query: 424 KMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQD 476
           ++D TA  N      V  +PTL  F     + V +++G R LD   +F+ S  +D
Sbjct: 270 EVDCTAERNICSKYSVRGYPTLLLF--RGGKKVSEHSGGRDLDSLHRFVLSQAKD 322



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 6/109 (5%)

Query: 366 KQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKM 425
           KQ +  L   NFE      + + F++F+APWCGHCK LAP W++L    +  E + I K+
Sbjct: 80  KQGLYELSASNFE--LHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKV 137

Query: 426 DSTANE--VEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 472
           D T +       +V  +PTL +F     + V  Y G+R L+  ++++ES
Sbjct: 138 DCTQHYELCSGNQVRGYPTLLWF--RDGKKVDQYKGKRDLESLREYVES 184



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 2/57 (3%)

Query: 73  EGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWL 129
           E +++ +AKVD T  SD+    GVRGYPT+K F+ G  A   +Y   R+   + NW+
Sbjct: 2   EDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEA--VKYQGPRDFQTLENWM 56


>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
          Length = 519

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 38/90 (42%), Positives = 55/90 (61%), Gaps = 1/90 (1%)

Query: 21  EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG-SEIRL 79
           +E   V  L   +F + +  H  +LV F+APWCGHCK + PE+ KAA  L  E  S   L
Sbjct: 273 DEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVL 332

Query: 80  AKVDATEESDLAQQYGVRGYPTIKFFRNGD 109
           A VDAT    LA+++ +  +PT+K+F+NG+
Sbjct: 333 AAVDATVNKALAERFHISEFPTLKYFKNGE 362



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 41/112 (36%), Positives = 59/112 (52%), Gaps = 5/112 (4%)

Query: 21  EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLA 80
           E++  VL L   NF E L   K+ LV FYAPWC HCK + P +   A   K +  +I  A
Sbjct: 394 EQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFK-DDRKIACA 452

Query: 81  KVDATEE--SDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLK 130
            VD  ++   DL QQ  V+GYPT  ++  G  A  ++Y + R      N+++
Sbjct: 453 AVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFA--EKYDSDRTELGFTNYIR 502



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 3/117 (2%)

Query: 20  PEEEDHVLVLRKSNFAEALAAH-KYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIR 78
           P  +D V +  + +F   L    K LL+ FYAPWC  CK + P + KAA +L+   + + 
Sbjct: 148 PGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGH-AVLA 206

Query: 79  LAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGP 135
              V ++E  ++ ++Y VRG+PTI +F  G      +   G  A+DIV WLK    P
Sbjct: 207 GMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYD-NYGSTAEDIVEWLKNPQPP 262



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 56/206 (27%), Positives = 87/206 (42%), Gaps = 25/206 (12%)

Query: 275 FKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEEL 334
           F+ AAE+  G+           D+  +L        +  A R    E    KY    E+ 
Sbjct: 315 FEKAAEALHGE----------ADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKY 364

Query: 335 TAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVL--VGKNFEDVAFDEKKNVFVEF 392
            A  +     +FLE    P       P  W++Q   VL  VG NF +    +KK+  V F
Sbjct: 365 -AVPVLRTKKKFLEWMQNPEAPPPPEPT-WEEQQTSVLHLVGDNFRET-LKKKKHTLVMF 421

Query: 393 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTAN------EVEAVKVHSFPTLKFF 446
           YAPWC HCK++ P +    + +KD   I  A +D   +      + EAVK   +PT  ++
Sbjct: 422 YAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVK--GYPTFHYY 479

Query: 447 PASADRTVIDYNGERTLDGFKKFLES 472
                +    Y+ +RT  GF  ++ +
Sbjct: 480 --HYGKFAEKYDSDRTELGFTNYIRA 503



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 61/239 (25%), Positives = 107/239 (44%), Gaps = 27/239 (11%)

Query: 241 TEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQR 300
           +E+   ++   E K  +++F     S     + +F+ AA   +G  +   ++   ++ + 
Sbjct: 158 SEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFEN 217

Query: 301 ILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQEL 360
           I E + ++        +   E+    ++ ++   TAE I E+    L+    P     E 
Sbjct: 218 IKEEYSVRGFPT----ICYFEKGRFLFQYDNYGSTAEDIVEW----LKNPQPPQPQVPET 269

Query: 361 PEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENI 420
           P   +   V  L  ++F+     E  +V V F+APWCGHCK++ P ++K  E      + 
Sbjct: 270 PWADEGGSVYHLTDEDFDQFV-KEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADS 328

Query: 421 --VIAKMDSTANEVEAVKVH--SFPTLKFFPASADRTVIDYNGER----TLDGFKKFLE 471
             V+A +D+T N+  A + H   FPTLK+F           NGE+     L   KKFLE
Sbjct: 329 SGVLAAVDATVNKALAERFHISEFPTLKYFK----------NGEKYAVPVLRTKKKFLE 377


>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
          Length = 698

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 48/131 (36%), Positives = 64/131 (48%), Gaps = 21/131 (16%)

Query: 2   LRRALLCLAVAA----------LVRADAPEEEDHVLVLRKSNFAEALA-AHKYLLVEFYA 50
           L R L+ LA AA          L RA     ED V VL   +   A A +    LV+FY+
Sbjct: 33  LPRLLVLLAAAAVGPGAGGAARLYRAG----EDAVWVLDSGSVRGATANSSAAWLVQFYS 88

Query: 51  PWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIKFFRNG 108
            WCGHC   AP +   AG ++   S IR+A +D  EE + A    Y +  YPT ++F+  
Sbjct: 89  SWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFK-- 146

Query: 109 DTASPKEYTAG 119
             A  KE+T G
Sbjct: 147 --AFTKEFTTG 155



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 5/64 (7%)

Query: 390 VEFYAPWCGHCKQLAPIWDKLGETYKDHENIV-IAKMDSTANEVEAV----KVHSFPTLK 444
           V+FY+ WCGHC   AP W  L    +D  + + +A +D    + +AV     +H +PT +
Sbjct: 84  VQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFR 143

Query: 445 FFPA 448
           +F A
Sbjct: 144 YFKA 147


>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
          Length = 166

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 5/91 (5%)

Query: 44  LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIK 103
           ++V+F+A WCG CK L P   K   K   +  ++ +AKVD  + +DLA +Y V   PT+ 
Sbjct: 81  VVVDFHAQWCGPCKILGPRLEKMVAK---QHGKVVMAKVDIDDHTDLAIEYEVSAVPTVL 137

Query: 104 FFRNGDTASPKEYTAGREADDIVNWLKKRTG 134
             +NGD     ++   ++ D +  +LKK  G
Sbjct: 138 AMKNGDVVD--KFVGIKDEDQLEAFLKKLIG 166



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 374 GKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVE 433
           G +F+D   + +  V V+F+A WCG CK L P  +K+    K H  +V+AK+D   +   
Sbjct: 67  GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM--VAKQHGKVVMAKVDIDDHTDL 124

Query: 434 AV--KVHSFPTLKFFPASADRTVID-YNGERTLDGFKKFLE 471
           A+  +V + PT+    A  +  V+D + G +  D  + FL+
Sbjct: 125 AIEYEVSAVPTVL---AMKNGDVVDKFVGIKDEDQLEAFLK 162


>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
           sapiens]
          Length = 793

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 4/78 (5%)

Query: 29  LRKSNFAE-ALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEE 87
           L    F+E  L    + +++FYAPWCG C+  APE+   A  +K    +++  KVD    
Sbjct: 675 LTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIK---GKVKAGKVDCQAY 731

Query: 88  SDLAQQYGVRGYPTIKFF 105
           +   Q+ G+R YPT+KF+
Sbjct: 732 AQTCQKAGIRAYPTVKFY 749



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 6/140 (4%)

Query: 21  EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLA 80
           +++  ++ L +  F  A+ + +   V FY+P C HC  LAP +   A   K     +R+ 
Sbjct: 126 DDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFA---KEVDGLLRIG 182

Query: 81  KVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTL 140
            V+  ++  L +  GV  YP++  FR+G   +P +Y   R  + +V++  +      T L
Sbjct: 183 AVNCGDDRMLCRMKGVNSYPSLFIFRSG--MAPVKYHGDRSKESLVSFAMQHVRSTVTEL 240

Query: 141 PDGAAAESLVESSEVAVIGF 160
             G    S ++++  A IG+
Sbjct: 241 WTGNFVNS-IQTAFAAGIGW 259



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 8/119 (6%)

Query: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104
           LV+F+APWC  C+AL PE  +A+  L     +++   +D T    L   Y ++ YPT   
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLY---GQLKFGTLDCTVHEGLCNMYNIQAYPTTVV 528

Query: 105 FRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVE--SSEVAVIGFF 161
           F   +     EY     A+ I+ +++    P+  +L      E + +   +EV ++ F+
Sbjct: 529 FNQSNI---HEYEGHHSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFY 584



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 26  VLVLRKSNFAEALAAHKY---LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKV 82
           V+ L  + F E +   K+    +V+FY+PWC  C+ L PE+ + A  L      I +  +
Sbjct: 558 VVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLT---GLINVGSI 614

Query: 83  DATEESDLAQQYGVRGYPTIKFF 105
           D  +      Q  V+ YP I+FF
Sbjct: 615 DCQQYHSFCAQENVQRYPEIRFF 637



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 20/75 (26%), Positives = 35/75 (46%)

Query: 372 LVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE 431
           L  + F +     K +  ++FYAPWCG C+  AP ++ L    K           + A  
Sbjct: 675 LTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQT 734

Query: 432 VEAVKVHSFPTLKFF 446
            +   + ++PT+KF+
Sbjct: 735 CQKAGIRAYPTVKFY 749



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 4/105 (3%)

Query: 359 ELPEDWDKQPVKVLVGKNFEDVAFDEKKNV--FVEFYAPWCGHCKQLAPIWDKLGETYKD 416
           E  ED     V  L    F ++    K N    V+FY+PWC  C+ L P W ++  T   
Sbjct: 548 EFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTG 607

Query: 417 HENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRT--VIDYNG 459
             N+         +      V  +P ++FFP  +++      YNG
Sbjct: 608 LINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNG 652



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 2/106 (1%)

Query: 364 WDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIA 423
           +D  P  + + +   D A +  +  FV FY+P C HC  LAP W    +       I   
Sbjct: 125 YDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAV 184

Query: 424 KMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469
                        V+S+P+L  F   +    + Y+G+R+ +    F
Sbjct: 185 NCGDDRMLCRMKGVNSYPSLFIF--RSGMAPVKYHGDRSKESLVSF 228



 Score = 35.8 bits (81), Expect = 0.095
 Identities = 21/91 (23%), Positives = 41/91 (45%), Gaps = 7/91 (7%)

Query: 383 DEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANE--VEAVKVHSF 440
           ++K+   V+F+APWC  C+ L P   +       +  +    +D T +E       + ++
Sbjct: 466 NDKEPWLVDFFAPWCPPCRALLPELRRASNLL--YGQLKFGTLDCTVHEGLCNMYNIQAY 523

Query: 441 PTLKFFPASADRTVIDYNGERTLDGFKKFLE 471
           PT   F  S    + +Y G  + +   +F+E
Sbjct: 524 PTTVVFNQS---NIHEYEGHHSAEQILEFIE 551


>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
          Length = 280

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 10/127 (7%)

Query: 9   LAVAALVRADAP---EEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAK 65
           LAV  L+   AP       +V V+   N+ E L      ++EFYAPWC  C+ L PE+  
Sbjct: 11  LAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGD--WMIEFYAPWCPACQNLQPEWES 68

Query: 66  AAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDI 125
            A     E  E+ +AKVD TE+  L+ ++ +   PTI   ++G+    + Y   R   D 
Sbjct: 69  FAE--WGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEF---RRYQGPRTKKDF 123

Query: 126 VNWLKKR 132
           +N++  +
Sbjct: 124 INFISDK 130



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 9/104 (8%)

Query: 369 VKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDST 428
           V+V+  +N+ ++    + +  +EFYAPWC  C+ L P W+   E  +D E + IAK+D T
Sbjct: 31  VRVITDENWRELL---EGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLE-VNIAKVDVT 86

Query: 429 ANEVEAVK--VHSFPTLKFFPASADRTVIDYNGERTLDGFKKFL 470
                + +  + + PT+       D     Y G RT   F  F+
Sbjct: 87  EQPGLSGRFIITALPTIYH---CKDGEFRRYQGPRTKKDFINFI 127


>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
           sapiens]
          Length = 604

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 2/63 (3%)

Query: 46  VEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIK 103
           VEF+A WCGHC A AP +   A  +KA    + LA +D  EE++ A  + + + G+PT++
Sbjct: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122

Query: 104 FFR 106
           FF+
Sbjct: 123 FFK 125



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 368 PVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIVIAKMD 426
           P+ +L            +    VEF+A WCGHC   AP W  L E  K     + +A +D
Sbjct: 41  PLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALD 100

Query: 427 STANEVEAV----KVHSFPTLKFFPA 448
                  AV     +  FPT++FF A
Sbjct: 101 CAEETNSAVCRDFNIPGFPTVRFFKA 126


>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
           sapiens]
          Length = 747

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 2/63 (3%)

Query: 46  VEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIK 103
           VEF+A WCGHC A AP +   A  +KA    + LA +D  EE++ A  + + + G+PT++
Sbjct: 63  VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVR 122

Query: 104 FFR 106
           FF+
Sbjct: 123 FFK 125



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 368 PVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIVIAKMD 426
           P+ +L            +    VEF+A WCGHC   AP W  L E  K     + +A +D
Sbjct: 41  PLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALD 100

Query: 427 STANEVEAV----KVHSFPTLKFFPA 448
                  AV     +  FPT++FF A
Sbjct: 101 CAEETNSAVCRDFNIPGFPTVRFFKA 126


>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
          Length = 399

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 86/370 (23%), Positives = 145/370 (39%), Gaps = 39/370 (10%)

Query: 23  EDHVLVLRKSNFAEALAAHKYLLVEFYAPWCG--------HCKALAPEYAKAAGKLKAEG 74
           +D V+ L + NF + L  +  L + ++ P             K +  E      + KA G
Sbjct: 31  KDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIG 90

Query: 75  SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG 134
                  VDA +E+ LA++ G     ++   +   T    E+     AD +V +L     
Sbjct: 91  ----FVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTI---EFDGEFAADVLVEFLLDLIE 143

Query: 135 PAATTLPDGAAAESLVESSE-VAVIGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDV 192
                +      ++     + + +IGFFK  +S+  K F +AAE     I F  T +  V
Sbjct: 144 DPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGV 203

Query: 193 FSKYQLDKDGVVLFKKF-DEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGG 251
             K  L  + V  ++ F DE         T+E L++F+K +Q P +     +   + +  
Sbjct: 204 AKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFETWED 263

Query: 252 EIK-THILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKE 310
           ++   HI+ F  KS  D    L   K  A              D+TDN   L    +  +
Sbjct: 264 DLNGIHIVAFAEKSDPDGYEFLEILKQVAR-------------DNTDNPD-LSILWIDPD 309

Query: 311 ECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVK 370
           + P   L+   E+  K      ++    +T+    ++E      L + E  EDW +    
Sbjct: 310 DFPL--LVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIED--- 364

Query: 371 VLVGK-NFED 379
           VL GK N ED
Sbjct: 365 VLSGKINTED 374


>gi|50592994 thioredoxin [Homo sapiens]
          Length = 105

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)

Query: 31  KSNFAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES 88
           K+ F EAL  A  K ++V+F A WCG CK + P +   + K     S +   +VD  +  
Sbjct: 8   KTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKY----SNVIFLEVDVDDCQ 63

Query: 89  DLAQQYGVRGYPTIKFFRNG 108
           D+A +  V+  PT +FF+ G
Sbjct: 64  DVASECEVKCMPTFQFFKKG 83



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 11/66 (16%)

Query: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMD-----STANEVEAVKVHSF 440
           K V V+F A WCG CK + P +  L E Y    N++  ++D       A+E E   V   
Sbjct: 21  KLVVVDFSATWCGPCKMIKPFFHSLSEKY---SNVIFLEVDVDDCQDVASECE---VKCM 74

Query: 441 PTLKFF 446
           PT +FF
Sbjct: 75  PTFQFF 80


>gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo
           sapiens]
          Length = 820

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 49/219 (22%), Positives = 89/219 (40%), Gaps = 17/219 (7%)

Query: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104
           +V FYA W     A    Y   A KLK   S + L +++  + SD+  +  V  +P IK 
Sbjct: 406 IVLFYAGWQAVSMAFLQSYIDVAVKLKGT-STMLLTRINCADWSDVCTKQNVTEFPIIKM 464

Query: 105 FRNGDTASPKEYTAGREADDIVNW--LKKRTGPA-------ATTLPDGAAAESLVESSEV 155
           ++ G+  +P  Y      +D++ +  L + + P        A     G   + L+  S V
Sbjct: 465 YKKGE--NPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSV 522

Query: 156 AVIGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDVF---SKYQLDKDGVVLFKKFDE 211
           +V+G F      + + F +A   +   +  GI S  DV    +KY      ++L +  + 
Sbjct: 523 SVLGLFSPTMKTAKEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEG 582

Query: 212 GRNNFE-GEVTKENLLDFIKHNQLPLVIEFTEQTAPKIF 249
              +        ++++  I    L +  E T +  P  F
Sbjct: 583 KIESIPLASTHAQDIVQIITDALLEMFPEITVENLPSYF 621



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 190 SDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTE-QTAPKI 248
           SDV +K  + +  ++   K  E   ++ G +  E+LL FI+ N++   +  T  Q A + 
Sbjct: 448 SDVCTKQNVTEFPIIKMYKKGENPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEY 507

Query: 249 FGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESF 282
             GE+   ++L+   SVS         KTA E F
Sbjct: 508 LSGELYKDLILY--SSVSVLGLFSPTMKTAKEDF 539


>gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo
           sapiens]
          Length = 825

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 49/219 (22%), Positives = 89/219 (40%), Gaps = 17/219 (7%)

Query: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104
           +V FYA W     A    Y   A KLK   S + L +++  + SD+  +  V  +P IK 
Sbjct: 411 IVLFYAGWQAVSMAFLQSYIDVAVKLKGT-STMLLTRINCADWSDVCTKQNVTEFPIIKM 469

Query: 105 FRNGDTASPKEYTAGREADDIVNW--LKKRTGPA-------ATTLPDGAAAESLVESSEV 155
           ++ G+  +P  Y      +D++ +  L + + P        A     G   + L+  S V
Sbjct: 470 YKKGE--NPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSV 527

Query: 156 AVIGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDVF---SKYQLDKDGVVLFKKFDE 211
           +V+G F      + + F +A   +   +  GI S  DV    +KY      ++L +  + 
Sbjct: 528 SVLGLFSPTMKTAKEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEG 587

Query: 212 GRNNFE-GEVTKENLLDFIKHNQLPLVIEFTEQTAPKIF 249
              +        ++++  I    L +  E T +  P  F
Sbjct: 588 KIESIPLASTHAQDIVQIITDALLEMFPEITVENLPSYF 626



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 190 SDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTE-QTAPKI 248
           SDV +K  + +  ++   K  E   ++ G +  E+LL FI+ N++   +  T  Q A + 
Sbjct: 453 SDVCTKQNVTEFPIIKMYKKGENPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEY 512

Query: 249 FGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESF 282
             GE+   ++L+   SVS         KTA E F
Sbjct: 513 LSGELYKDLILY--SSVSVLGLFSPTMKTAKEDF 544


>gi|227430327 calsequestrin 1 [Homo sapiens]
          Length = 396

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 78/385 (20%), Positives = 158/385 (41%), Gaps = 49/385 (12%)

Query: 2   LRRALLCLAVAALVRA--------DAPEEE--DHVLVLRKSNFAEALAAHKYLLVEFYAP 51
           LR ALL L V    ++        D PE +  D V+ +   N+      ++ L + ++ P
Sbjct: 15  LRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEP 74

Query: 52  WCGHCKALAPEYAKAAGK----------LKAEGSE---IRLAKVDATEESDLAQQYGVRG 98
                    PE  KA+ +          L A+  E   +    VD+ +++ +A++ G+  
Sbjct: 75  ---------PEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTE 125

Query: 99  YPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVE-SSEVAV 157
             ++  F+  +     EY     AD IV +L          +      ++      E+ +
Sbjct: 126 VDSMYVFKGDEVI---EYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKL 182

Query: 158 IGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNF 216
           IG+FK  +S+  K F  AAE     IPF  T +S V  K  L  + +  ++ F E     
Sbjct: 183 IGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTI 242

Query: 217 EGEV-TKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIK-THILLFLPKSVSDYDGKLSN 274
             +  ++E +++F++ ++   + +   ++  + +  ++   HI+ F  ++  D    L  
Sbjct: 243 PDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFLET 302

Query: 275 FKTAAE--SFKGKILFIFIDSDHTDNQRILEFF------GLKKEECPAVRLITLEEEMTK 326
            K  A+  +    +  I+ID D  D   ++ ++       L   +   V +   +    +
Sbjct: 303 LKAVAQDNTENPDLSIIWIDPD--DFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWME 360

Query: 327 YKPESEELTAERITEFCHRFLEGKI 351
              E +  +AE + ++    LEG+I
Sbjct: 361 MDDEEDLPSAEELEDWLEDVLEGEI 385


>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
          Length = 958

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 5/144 (3%)

Query: 317 LITLEEEMTKYKPESEELTAERITEFCHRF--LEGKIKPHLMSQELPEDWDKQPVKVLVG 374
           ++ ++EE        + L    +  F   F  L   +K HL+     +   +  +  +  
Sbjct: 611 IVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTT 670

Query: 375 KNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVE- 433
             F +V   +K++V + +YAPWCG C  L  I+ +L       +   +A++D + N++  
Sbjct: 671 DTFWEVVL-QKQDVLLLYYAPWCGFCPSLNHIFIQLARNL-PMDTFTVARIDVSQNDLPW 728

Query: 434 AVKVHSFPTLKFFPASADRTVIDY 457
              V   PT+ FFP +     + Y
Sbjct: 729 EFMVDRLPTVLFFPCNRKDLSVKY 752



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 34  FAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQ 93
           F E +   + +L+ +YAPWCG C +L   + + A  L  +     +A++D + ++DL  +
Sbjct: 673 FWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMD--TFTVARIDVS-QNDLPWE 729

Query: 94  YGVRGYPTIKFF 105
           + V   PT+ FF
Sbjct: 730 FMVDRLPTVLFF 741



 Score = 36.2 bits (82), Expect = 0.072
 Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 19/203 (9%)

Query: 44  LLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDA-TEESDLAQQYGVRGYPTI 102
           +L+ FYAPWCG   A   E  +AA +L     ++    ++    +    +Q     +P I
Sbjct: 128 VLLFFYAPWCGQSIAARAEIEQAASRL---SDQVLFVAINCWWNQGKCRKQKHFFYFPVI 184

Query: 103 KFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFK 162
             +    +  P EY     A  I  ++++   P    +P  +     + + E  V+G+F+
Sbjct: 185 YLYHR--SFGPIEYKGPMSAVYIEKFVRRVMKP-LLYIPSQSELLDFLSNYEPGVLGYFE 241

Query: 163 DVESDSAKQFLQ---------AAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGR 213
              S     +L            + +  + FG+ +N  +     L   G V   +     
Sbjct: 242 FSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTS 301

Query: 214 NNFEGEV---TKENLLDFIKHNQ 233
             F  EV   T EN+  +   NQ
Sbjct: 302 LVFPREVLNYTAENICKWALENQ 324


>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 10/100 (10%)

Query: 351 IKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDE--KKNVFVEFYAPWCGHCKQLAPIWD 408
           +KP   + E PE  DK  VKV++ K   + +  E  ++ V V+F A WCG C+ + P + 
Sbjct: 368 LKPEEETMEFPEG-DK--VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH 424

Query: 409 KLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTLKFF 446
            L      HE++V  ++D+   E  V    +   PT +F+
Sbjct: 425 ALS---VKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFY 461



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 20  PEEEDHVLVLRKSNFAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEI 77
           PE +   ++L K +F  +L  A  + + V+F A WCG C+ + P +      L  +  ++
Sbjct: 378 PEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFF----HALSVKHEDV 433

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFR 106
              +VDA    ++ ++  +   PT +F++
Sbjct: 434 VFLEVDADNCEEVVRECAIMCVPTFQFYK 462


>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
           sapiens]
          Length = 553

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 10/100 (10%)

Query: 351 IKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDE--KKNVFVEFYAPWCGHCKQLAPIWD 408
           +KP   + E PE  DK  VKV++ K   + +  E  ++ V V+F A WCG C+ + P + 
Sbjct: 435 LKPEEETMEFPEG-DK--VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH 491

Query: 409 KLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTLKFF 446
            L      HE++V  ++D+   E  V    +   PT +F+
Sbjct: 492 ALS---VKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFY 528



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 20  PEEEDHVLVLRKSNFAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEI 77
           PE +   ++L K +F  +L  A  + + V+F A WCG C+ + P +      L  +  ++
Sbjct: 445 PEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFF----HALSVKHEDV 500

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFR 106
              +VDA    ++ ++  +   PT +F++
Sbjct: 501 VFLEVDADNCEEVVRECAIMCVPTFQFYK 529


>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 10/100 (10%)

Query: 351 IKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDE--KKNVFVEFYAPWCGHCKQLAPIWD 408
           +KP   + E PE  DK  VKV++ K   + +  E  ++ V V+F A WCG C+ + P + 
Sbjct: 368 LKPEEETMEFPEG-DK--VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFH 424

Query: 409 KLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTLKFF 446
            L      HE++V  ++D+   E  V    +   PT +F+
Sbjct: 425 ALS---VKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFY 461



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 20  PEEEDHVLVLRKSNFAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEI 77
           PE +   ++L K +F  +L  A  + + V+F A WCG C+ + P +      L  +  ++
Sbjct: 378 PEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFF----HALSVKHEDV 433

Query: 78  RLAKVDATEESDLAQQYGVRGYPTIKFFR 106
              +VDA    ++ ++  +   PT +F++
Sbjct: 434 VFLEVDADNCEEVVRECAIMCVPTFQFYK 462


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
           sapiens]
          Length = 349

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/154 (24%), Positives = 65/154 (42%), Gaps = 13/154 (8%)

Query: 5   ALLCLAVAALVRADAPEE------EDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKA 58
           ALL   +AA+     PEE      +  V  +  SN+   L      +++FYAPWC  C+ 
Sbjct: 12  ALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWT--LVMEGEWMLKFYAPWCPSCQQ 69

Query: 59  LAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTA 118
              E+   A     E  +I + KVD  +E  L+ ++ V   P     ++G     + Y  
Sbjct: 70  TDSEWEAFA--KNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIF---RRYRG 124

Query: 119 GREADDIVNWLKKRTGPAATTLPDGAAAESLVES 152
               +D+ N++ ++   +   L    +  SL  S
Sbjct: 125 PGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMS 158



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 9/19 (47%), Positives = 13/19 (68%)

Query: 390 VEFYAPWCGHCKQLAPIWD 408
           ++FYAPWC  C+Q    W+
Sbjct: 57  LKFYAPWCPSCQQTDSEWE 75


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 4/70 (5%)

Query: 38  LAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVR 97
           L A   L+V F+APW   C  +    A+ A +L     ++   K++A    +++++Y + 
Sbjct: 28  LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL----PQVSFVKLEAEGVPEVSEKYEIS 83

Query: 98  GYPTIKFFRN 107
             PT  FF+N
Sbjct: 84  SVPTFLFFKN 93



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 5/67 (7%)

Query: 385 KKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDS--TANEVEAVKVHSFPT 442
           K  + V F+APW   C Q+  +   + E  K+   +   K+++       E  ++ S PT
Sbjct: 31  KSLLVVHFWAPWAPQCAQMNEV---MAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPT 87

Query: 443 LKFFPAS 449
             FF  S
Sbjct: 88  FLFFKNS 94


>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
           sapiens]
          Length = 258

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 8/73 (10%)

Query: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGV------RG 98
           +VEF+A W   C++ AP YA  + K    G  +   KVD    +D++ +Y V      + 
Sbjct: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTG--LNFGKVDVGRYTDVSTRYKVSTSPLTKQ 178

Query: 99  YPTIKFFRNGDTA 111
            PT+  F+ G  A
Sbjct: 179 LPTLILFQGGKEA 191



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 378 EDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETY 414
           E++  D++    VEF+A W   C+  API+  L   Y
Sbjct: 110 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,843,970
Number of Sequences: 37866
Number of extensions: 852016
Number of successful extensions: 4158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 3583
Number of HSP's gapped (non-prelim): 468
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.