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Search of human proteins with 19923999
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens] 505 e-143
gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens] 371 e-103
gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens] 106 2e-23
gi|239751182 PREDICTED: hypothetical protein [Homo sapiens] 106 2e-23
gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens] 106 2e-23
gi|22749023 transmembrane protein 56 [Homo sapiens] 43 2e-04
gi|195972890 unc-84 homolog A isoform a [Homo sapiens] 33 0.23
gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] 33 0.30
gi|239751443 PREDICTED: hypothetical protein [Homo sapiens] 33 0.30
gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo ... 33 0.30
gi|6912464 latrophilin 2 precursor [Homo sapiens] 30 1.9
gi|190358512 transmembrane protein 184C [Homo sapiens] 30 2.5
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens] 29 4.3
gi|109638743 hypothetical protein LOC83723 [Homo sapiens] 29 4.3
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 28 5.6
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 28 5.6
gi|61656212 olfactory receptor, family 8, subfamily U, member 9 ... 28 7.4
gi|5174535 melanocortin 5 receptor [Homo sapiens] 28 9.6
>gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens]
Length = 247
Score = 505 bits (1301), Expect = e-143
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MPRLLHPALPLLLGATLTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGI 60
MPRLLHPALPLLLGATLTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGI
Sbjct: 1 MPRLLHPALPLLLGATLTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGI 60
Query: 61 WALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVM 120
WALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVM
Sbjct: 61 WALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVM 120
Query: 121 AMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYF 180
AMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYF
Sbjct: 121 AMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYF 180
Query: 181 LFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQH 240
LFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQH
Sbjct: 181 LFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQH 240
Query: 241 KDKFLTE 247
KDKFLTE
Sbjct: 241 KDKFLTE 247
>gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens]
Length = 200
Score = 371 bits (952), Expect = e-103
Identities = 182/182 (100%), Positives = 182/182 (100%)
Query: 66 VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF 125
VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF
Sbjct: 19 VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF 78
Query: 126 FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA 185
FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA
Sbjct: 79 FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA 138
Query: 186 PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL 245
PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL
Sbjct: 139 PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL 198
Query: 246 TE 247
TE
Sbjct: 199 TE 200
>gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]
Length = 264
Score = 106 bits (264), Expect = 2e-23
Identities = 72/236 (30%), Positives = 117/236 (49%), Gaps = 8/236 (3%)
Query: 11 LLLGAT-LTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQT 69
L+ GA+ L FR L L RLP P D W+W NL VS AHS++SG ALL +
Sbjct: 7 LVAGASFLAFRGLHWGLRRLPTPESAARD---RWQWWNLCVSLAHSLLSGTGALLGLSLY 63
Query: 70 PDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGI 129
P M + +LV S GYF+ D D++ + +W+ L HH++ + + +
Sbjct: 64 PQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAV 123
Query: 130 FWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAY 189
+VG +++LL+E+++ L +R ++ +S L + V + +L LFRL P +
Sbjct: 124 LSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGW 183
Query: 190 LTHFFLRYVNQRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 241
++ + R +Q L LG L+ + +M II R+L +D H P H+
Sbjct: 184 MSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]
Length = 264
Score = 106 bits (264), Expect = 2e-23
Identities = 72/236 (30%), Positives = 117/236 (49%), Gaps = 8/236 (3%)
Query: 11 LLLGAT-LTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQT 69
L+ GA+ L FR L L RLP P D W+W NL VS AHS++SG ALL +
Sbjct: 7 LVAGASFLAFRGLHWGLRRLPTPESAARD---RWQWWNLCVSLAHSLLSGTGALLGLSLY 63
Query: 70 PDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGI 129
P M + +LV S GYF+ D D++ + +W+ L HH++ + + +
Sbjct: 64 PQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAV 123
Query: 130 FWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAY 189
+VG +++LL+E+++ L +R ++ +S L + V + +L LFRL P +
Sbjct: 124 LSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGW 183
Query: 190 LTHFFLRYVNQRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 241
++ + R +Q L LG L+ + +M II R+L +D H P H+
Sbjct: 184 MSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]
Length = 264
Score = 106 bits (264), Expect = 2e-23
Identities = 72/236 (30%), Positives = 117/236 (49%), Gaps = 8/236 (3%)
Query: 11 LLLGAT-LTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQT 69
L+ GA+ L FR L L RLP P D W+W NL VS AHS++SG ALL +
Sbjct: 7 LVAGASFLAFRGLHWGLRRLPTPESAARD---RWQWWNLCVSLAHSLLSGTGALLGLSLY 63
Query: 70 PDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGI 129
P M + +LV S GYF+ D D++ + +W+ L HH++ + + +
Sbjct: 64 PQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAV 123
Query: 130 FWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAY 189
+VG +++LL+E+++ L +R ++ +S L + V + +L LFRL P +
Sbjct: 124 LSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGW 183
Query: 190 LTHFFLRYVNQRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 241
++ + R +Q L LG L+ + +M II R+L +D H P H+
Sbjct: 184 MSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|22749023 transmembrane protein 56 [Homo sapiens]
Length = 263
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 45 WHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIETAW---SLSGYLLVCFSAGYFIHDTVD 101
W++ +VS HS+V GI+ L D + + W SL+ + + ++GY I D
Sbjct: 49 WNSRVVSTCHSLVVGIFGLYIF--LFDEATKADPLWGGPSLAN-VNIAIASGYLISDLSI 105
Query: 102 IVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMK-IS 160
I+ + +++HH ++ A++ + G LL E+S+ F+ R + +
Sbjct: 106 IILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALK 165
Query: 161 NAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMI 218
+ +N + V++F+ R+A + L H+ Y T LG+L+ L +I
Sbjct: 166 YPKFSKAIVINGILMTVVFFIVRIA--SMLPHYGFMYSVYGTEPYIRLGVLIQLSWVI 221
>gi|195972890 unc-84 homolog A isoform a [Homo sapiens]
Length = 785
Score = 33.1 bits (74), Expect = 0.23
Identities = 18/60 (30%), Positives = 27/60 (45%)
Query: 100 VDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKI 159
+ V +R +W L V+A G SG+FW +G L+ N+FL R + I
Sbjct: 230 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI 289
>gi|239756943 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 32.7 bits (73), Expect = 0.30
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 15 ATLTFRALR----RALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTP 70
A L RALR +A LP P H++A+P RT+R L+ S +G+W + P
Sbjct: 597 AALQVRALRLHRNKACPALPAPTHLQAEPTRTFR---LVREMGVSGPAGVWVVAVDCHAP 653
Query: 71 DMLVEIETAWSLSG 84
A SLSG
Sbjct: 654 ACGRAHTHAHSLSG 667
>gi|239751443 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 32.7 bits (73), Expect = 0.30
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 15 ATLTFRALR----RALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTP 70
A L RALR +A LP P H++A+P RT+R L+ S +G+W + P
Sbjct: 597 AALQVRALRLHRNKACPALPAPTHLQAEPTRTFR---LVREMGVSGPAGVWVVAVDCHAP 653
Query: 71 DMLVEIETAWSLSG 84
A SLSG
Sbjct: 654 ACGRAHTHAHSLSG 667
>gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo
sapiens]
Length = 791
Score = 32.7 bits (73), Expect = 0.30
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 15 ATLTFRALR----RALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTP 70
A L RALR +A LP P H++A+P RT+R L+ S +G+W + P
Sbjct: 605 AALQVRALRLHRNKACPALPAPTHLQAEPTRTFR---LVREMGVSGPAGVWVVAVDCHAP 661
Query: 71 DMLVEIETAWSLSG 84
A SLSG
Sbjct: 662 ACGRAHTHAHSLSG 675
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 30.0 bits (66), Expect = 1.9
Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 29/163 (17%)
Query: 49 LVSFAHSIVSGIWALLCVWQTPDMLVEI-ETAWSLSGYLLVCFSAGYFIHDTV------- 100
L +FA + G+ L MLVE+ E+ +S Y V AGY TV
Sbjct: 909 LAAFAWMCLEGVQLYL-------MLVEVFESEYSRKKYYYV---AGYLFPATVVGVSAAI 958
Query: 101 DIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKIS 160
D + G +A W ++ ++ + WS F+G +L+ + + +T+ M+K S
Sbjct: 959 DYKSYGTEKACWLHVDNYFI----------WS-FIGPVTFIILLNIIFLVITLCKMVKHS 1007
Query: 161 NAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTL 203
N R+ + V+ L F L ++N+ T+
Sbjct: 1008 NTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETI 1050
>gi|190358512 transmembrane protein 184C [Homo sapiens]
Length = 438
Score = 29.6 bits (65), Expect = 2.5
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 41 RTWR-WHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIET-AWSLSGYLLV 88
R WR W LV+ + + + LCVW+ + V I T AW ++G L+
Sbjct: 8 RNWRQWIRPLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLL 57
>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
Length = 202
Score = 28.9 bits (63), Expect = 4.3
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 13/63 (20%)
Query: 81 SLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVL 140
SL G L+C +A ++ +G+T+ + E +H+ FFSGI VGGG+L
Sbjct: 13 SLVGLALLCIAANILLY-----FPNGETKYASE---NHLSRFVWFFSGI-----VGGGLL 59
Query: 141 TLL 143
LL
Sbjct: 60 MLL 62
>gi|109638743 hypothetical protein LOC83723 [Homo sapiens]
Length = 274
Score = 28.9 bits (63), Expect = 4.3
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 10/130 (7%)
Query: 103 VASGQTRASWEYLVHHV-MAMGAFFSGIFWSSFVGGGVL--TLLVEVSNIFLTIRMMMKI 159
+A G + ++HH M + F + W G L L+ EVS F+ + ++
Sbjct: 121 IARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQ 180
Query: 160 SNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL-------LGILL 212
Q LL++VN + L+ + R+ YL + R+ L L LG L
Sbjct: 181 YKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAAL 240
Query: 213 MLDVMIIIYF 222
+L + +F
Sbjct: 241 LLAPQLYWFF 250
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 28.5 bits (62), Expect = 5.6
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 83 SGYLLVCFSAGYFIHDTVDIVAS--GQTRASWEYLVHHVMAMGAFFSGIFW 131
S L V + + TV + G R SW Y++ V + FF+GIF+
Sbjct: 107 SSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFY 157
>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
[Homo sapiens]
Length = 215
Score = 28.5 bits (62), Expect = 5.6
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 83 SGYLLVCFSAGYFIHDTVDIVAS--GQTRASWEYLVHHVMAMGAFFSGIFW 131
S L V + + TV + G R SW Y++ V + FF+GIF+
Sbjct: 149 SSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFY 199
>gi|61656212 olfactory receptor, family 8, subfamily U, member 9
[Homo sapiens]
Length = 309
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 149 IFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL 207
+FL+I + + N LL R ++ +N MYF L+ A++ + + + LG FL
Sbjct: 30 LFLSIYLFTVVGNLGLILLIRTDEKLNTPMYFF--LSNLAFVDFCYSSVITPKMLGNFL 86
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 27.7 bits (60), Expect = 9.6
Identities = 44/207 (21%), Positives = 78/207 (37%), Gaps = 36/207 (17%)
Query: 58 SGIWALLCVWQTPDMLVEIETAW-SLSGYLL----------------------VCFSAGY 94
S ++ +C DMLV + +AW +++ YLL +C S
Sbjct: 69 SPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVA 128
Query: 95 FIHDTVDIVASGQTRASWEYLVHHVMA---MGAFFSGIFWSSFVGGGVLTLLVEVSNIFL 151
+ + I + HH+M GA +GI W+ G G++ +L S
Sbjct: 129 SMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGI-WAFCTGCGIVFILYSES---- 183
Query: 152 TIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGIL 211
T ++ IS L V+ Y++ M+ L R + QRT + +
Sbjct: 184 TYVILCLISMFFAMLFLLVSLYIH--MFLLARTHVKRIAALPGASSARQRTSMQGAVTVT 241
Query: 212 LMLDVMIII---YFSRLLRSDFCPEHV 235
++L V + +F L CP+++
Sbjct: 242 MLLGVFTVCWAPFFLHLTLMLSCPQNL 268
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.333 0.143 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,756,072
Number of Sequences: 37866
Number of extensions: 346550
Number of successful extensions: 897
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 882
Number of HSP's gapped (non-prelim): 18
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.