Search of human proteins with 19923971

Search of human proteins with 19923971

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923971 coiled-coil domain containing 5 [Homo sapiens]
         (278 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923971 coiled-coil domain containing 5 [Homo sapiens]            532   e-151
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    47   2e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    45   9e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     45   9e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    44   2e-04
gi|38570058 hypothetical protein LOC80129 [Homo sapiens]               43   3e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       43   3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       43   3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        43   3e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           43   3e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           43   3e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           43   3e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               43   3e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    42   5e-04
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    42   5e-04
gi|4502443 dystonin isoform 1e precursor [Homo sapiens]                42   5e-04
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [...    42   5e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             42   6e-04
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    42   8e-04
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom...    42   8e-04
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    42   8e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    42   8e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    41   0.001
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    41   0.001
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    41   0.001
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    41   0.001
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    41   0.001
gi|71061468 centromere protein E [Homo sapiens]                        41   0.001
gi|38045919 huntingtin interacting protein 1 [Homo sapiens]            41   0.001
gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens]    41   0.001

>gi|19923971 coiled-coil domain containing 5 [Homo sapiens]
          Length = 278

 Score =  532 bits (1371), Expect = e-151
 Identities = 278/278 (100%), Positives = 278/278 (100%)

Query: 1   MEPQEERETQVAAWLKKIFGDHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQ 60
           MEPQEERETQVAAWLKKIFGDHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQ
Sbjct: 1   MEPQEERETQVAAWLKKIFGDHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQ 60

Query: 61  KASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVN 120
           KASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVN
Sbjct: 61  KASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVN 120

Query: 121 DLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQ 180
           DLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQ
Sbjct: 121 DLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQ 180

Query: 181 NMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLES 240
           NMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLES
Sbjct: 181 NMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLES 240

Query: 241 YLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL 278
           YLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL
Sbjct: 241 YLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL 278


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 61/225 (27%), Positives = 102/225 (45%), Gaps = 21/225 (9%)

Query: 47   RDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALE 106
            + R+   ++ + KQK  E +SE        +ES      +LS+   +  NA  +S   LE
Sbjct: 1445 KQRNFDKILAEWKQKYEESQSE--------LESSQKEARSLSTELFKLKNAYEESLEHLE 1496

Query: 107  TKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKC-LQEDVKKAE 165
            T      +    ++DLT  L      S +   ELEK+ K L A    EK  LQ  +++AE
Sbjct: 1497 TFKRENKNLQEEISDLTEQL----GSSGKTIHELEKVRKQLEA----EKMELQSALEEAE 1548

Query: 166  LHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLA 225
              L  E  K+   R  ++F + K+E  R   +  EE   A+     +   SL    +   
Sbjct: 1549 ASLEHEEGKI--LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVV-DSLQTSLDAET 1605

Query: 226  RLKQQTIPLKKKLESYLDLMP-NPSLAQVKIEEAKRELDSIEAEL 269
            R + + + +KKK+E  L+ M    S A     EA++++ S+++ L
Sbjct: 1606 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLL 1650



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 66/299 (22%), Positives = 126/299 (42%), Gaps = 35/299 (11%)

Query: 1    MEPQEERETQVAAWLKKIFGD-----HPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVI 55
            +E +EE   ++ A  +K+  +       I   E+     E   H +E N+V++    +  
Sbjct: 926  LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE-NKVKNLTEEMA- 983

Query: 56   EDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASF 115
              L +  ++   E K LQ+   ++++   A         +N L  + V LE +   L   
Sbjct: 984  -GLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-----VNTLTKAKVKLEQQVDDLEGS 1037

Query: 116  IPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKV 175
            +     +  DL R K K E    +L+  ++++      ++ L E +KK +  L+   A++
Sbjct: 1038 LEQEKKVRMDLERAKRKLEG---DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094

Query: 176  DNRRQNMDFLKAKSEEFRFGIKAAEEQLSA--------RGMDASLSHQSLVALSEKLARL 227
            ++ +     L+ K +E +  I+  EE+L A          + + LS + L  +SE+L   
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRE-LEEISERLEEA 1153

Query: 228  KQQT---IPLKKKLESYLDLMPNPSLAQVKIEEA------KRELDSIEAELTRRVDMME 277
               T   I + KK E+    M           EA      K+  DS+ AEL  ++D ++
Sbjct: 1154 GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSV-AELGEQIDNLQ 1211



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 49/248 (19%), Positives = 101/248 (40%), Gaps = 21/248 (8%)

Query: 37   LHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYL- 95
            L  L +  +++  D     +DLK+  +  E     LQ  L E          +  SR L 
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEE---LRAVVEQTERSRKLA 1702

Query: 96   -NALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLE 154
               L++++  ++   +   S I     + +DL + +++ EE   E    E+     +   
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDA 1762

Query: 155  KCLQEDVKKAE---LHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLS-----AR 206
              + E++KK +    HL  ER K +  +   D      E  +  +K  ++QL       R
Sbjct: 1763 AMMAEELKKEQDTSAHL--ERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820

Query: 207  GMDASL------SHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKR 260
             ++  L      + +S+  + +   R+K+ T   ++  ++ L L       Q+K++  KR
Sbjct: 1821 ELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKR 1880

Query: 261  ELDSIEAE 268
            + +  E +
Sbjct: 1881 QAEEAEEQ 1888



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 27/134 (20%), Positives = 61/134 (45%), Gaps = 7/134 (5%)

Query: 101  SAVALETKDTSLASFIPAVNDLTSDLFRTKSKSE----EIKIELEKLEKNLTATLVLEKC 156
            +A AL  K    A  +  + +   +L R K K E    E K+EL+ +  N+   +  +  
Sbjct: 1188 TAAALRKKH---ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN 1244

Query: 157  LQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQS 216
            L++  +  E  ++  R+K +  +++++ L ++  + +        QL  +    S   + 
Sbjct: 1245 LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304

Query: 217  LVALSEKLARLKQQ 230
             +  +++L  LK+Q
Sbjct: 1305 KLTYTQQLEDLKRQ 1318



 Score = 29.3 bits (64), Expect = 4.0
 Identities = 57/274 (20%), Positives = 115/274 (41%), Gaps = 32/274 (11%)

Query: 16   KKIFGDHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLV---IEDLKQKASEYESEAKYL 72
            +K+ GD  + Q  +     +    L ER + +D ++  +   IED +   S+ + + K L
Sbjct: 1053 RKLEGDLKLTQESIMDLEND-KQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKEL 1111

Query: 73   QDLLME---------SVNFSPANLSSTGSRYLNALVD--------SAVALETKDTSLASF 115
            Q  + E         +       L S  SR L  + +        ++V +E      A F
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEF 1171

Query: 116  IPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLE-KCLQEDVKKAELHLSTERAK 174
                  +  DL     + E     L K   +  A L  +   LQ   +K E   S  + +
Sbjct: 1172 ----QKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227

Query: 175  VDNRRQNMD-FLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIP 233
            +D+   NM+  +KAK+   +   +  E+Q++     A  + +S+  L+ + A+L+ +   
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKM-CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGE 1286

Query: 234  LKKKLESYLDLMPNPSLAQV----KIEEAKRELD 263
            L ++L+    L+   +  ++    ++E+ KR+L+
Sbjct: 1287 LSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE 1320


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 57/235 (24%), Positives = 101/235 (42%), Gaps = 33/235 (14%)

Query: 59   KQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPA 118
            K+K S  E+  + L DL +E                +N L+     LE +   L   +  
Sbjct: 998  KEKKSLQEAHQQTLDDLQVEEDK-------------VNGLIKINAKLEQQTDDLEGSLEQ 1044

Query: 119  VNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNR 178
               L +DL R K K E    +L+  ++++      ++ ++E +KK E  LS  +AK+D+ 
Sbjct: 1045 EKKLRADLERAKRKLEG---DLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDE 1101

Query: 179  RQNMDFLKAKSEEFRFGIKAAEEQLSA-RGMDASLSHQ------SLVALSEKLARLKQQT 231
            + +    + K +E +  I+  EE++ A   + A +  Q       L  +SE+L      T
Sbjct: 1102 QVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGAT 1161

Query: 232  ---IPLKKKLESYLDLMPNPSLAQVKIEEA------KRELDSIEAELTRRVDMME 277
               I + KK E+    M           EA      K++ DS+ AEL  ++D ++
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSV-AELGEQIDNLQ 1215



 Score = 36.6 bits (83), Expect = 0.025
 Identities = 49/221 (22%), Positives = 86/221 (38%), Gaps = 34/221 (15%)

Query: 56   EDLKQKASEYESEAKYLQDL---LMESVNFSPANLSSTGSRYLNA------LVDSAVALE 106
            E  K++ +  E+  K L++    L++  N     + S     ++A      L+ S + LE
Sbjct: 861  ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLE 920

Query: 107  TKDTSLASFIPAVNDLTSDLFRTKSKSEE----IKIELEKLEKNLTATLVLEKCLQEDVK 162
             K   L   +    ++ S+L   K   E+    +K +++ LE  LT              
Sbjct: 921  AKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT-------------- 966

Query: 163  KAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSE 222
            K E        KV N  + M  L+    +     K+ +E       D  +    +  L +
Sbjct: 967  KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIK 1026

Query: 223  KLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELD 263
              A+L+QQT  L+  LE    L       +  +E AKR+L+
Sbjct: 1027 INAKLEQQTDDLEGSLEQEKKL-------RADLERAKRKLE 1060



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 59/280 (21%), Positives = 117/280 (41%), Gaps = 41/280 (14%)

Query: 9    TQVAAWLKKIFGDHPIPQYEVNP-RTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYES 67
            ++VA W  K         YE +  + TE L    ++   R ++     E    K +  E 
Sbjct: 1370 SEVAQWRTK---------YETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEK 1420

Query: 68   EAKYLQ----DLL--MESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVND 121
              + LQ    DL+  +E  + + A L      +   L +    L+     L +       
Sbjct: 1421 TKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRS 1480

Query: 122  LTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQN 181
            L+++LF+ ++  EE+  +LE L +         K LQE++      L+ + A+     Q 
Sbjct: 1481 LSTELFKMRNAYEEVVDQLETLRRE-------NKNLQEEIS----DLTEQIAETGKNLQE 1529

Query: 182  MDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESY 241
             +  K   E+ +  ++ A E+     ++ SL H+       K+ R++ +   +K +L+  
Sbjct: 1530 AEKTKKLVEQEKSDLQVALEE-----VEGSLEHE-----ESKILRVQLELSQVKSELDRK 1579

Query: 242  LDLMPNPSLAQVK--IEEAKRELDSI-EAELTRRVDMMEL 278
            + +  +  + Q+K   + A   L S+ +AE+  R D + L
Sbjct: 1580 V-IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRL 1618



 Score = 33.5 bits (75), Expect = 0.21
 Identities = 26/116 (22%), Positives = 55/116 (47%), Gaps = 5/116 (4%)

Query: 157 LQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQS 216
           ++ED ++ +  L+   A+     + M  L  +  + +  +++  E L    MDA    + 
Sbjct: 856 MKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL----MDAEERCEG 911

Query: 217 LVALSEKL-ARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTR 271
           L+     L A++K+ T  L+++ E   +L+      + K    KR++D +E  LT+
Sbjct: 912 LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTK 967



 Score = 28.5 bits (62), Expect = 6.8
 Identities = 25/122 (20%), Positives = 53/122 (43%), Gaps = 4/122 (3%)

Query: 113  ASFIPAVNDLTSDLFRTKSKSE----EIKIELEKLEKNLTATLVLEKCLQEDVKKAELHL 168
            A  +  + +   +L R K K E    E+K+E++ +  N+ A    +  ++   +  E   
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260

Query: 169  STERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLK 228
            S  +AK + + Q +  L  +    +        ++  +    S   +S  AL+++L  LK
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320

Query: 229  QQ 230
            +Q
Sbjct: 1321 RQ 1322



 Score = 28.5 bits (62), Expect = 6.8
 Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 4/111 (3%)

Query: 157  LQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQS 216
            LQ   +K E   S  + ++D+   N++ L           +  E+Q S          Q 
Sbjct: 1214 LQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQL 1273

Query: 217  LVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQ----VKIEEAKRELD 263
            +  L+ + ARL+ Q   L  ++E    L+   + ++     ++EE KR+++
Sbjct: 1274 IHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQME 1324


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 49/276 (17%), Positives = 115/276 (41%), Gaps = 35/276 (12%)

Query: 33  TTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQD--------LLMESVNFSP 84
           T  +  H +E   ++ +   L  E L+    +Y++E + L++        LL +      
Sbjct: 606 TVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 665

Query: 85  ANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEK-- 142
           A++     + L  L      LE+  + L+  + A + L  +L   K +++++K ELE   
Sbjct: 666 AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM 725

Query: 143 --------------LEKNLTATLVLEKCLQEDVKKAEL-------HLSTERAKVDNRRQN 181
                         ++++  +    EK L++ + + EL       HL   +A V+N   +
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEAD 785

Query: 182 MDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESY 241
           +   + + ++    +   +   SA         + L  L +KL  L+ + I L K++   
Sbjct: 786 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 845

Query: 242 ----LDLMPNPSLAQVKIEEAKRELDSIEAELTRRV 273
                D+       ++++++  ++L+   +E+ ++V
Sbjct: 846 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 881



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 70/317 (22%)

Query: 15   LKKIFGDHPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQD 74
            L+K  G+      E     T++   LSE        V L+ E+LK+K  E  S +K L D
Sbjct: 1323 LQKEGGNQQQAASEKESCITQLKKELSENINA----VTLMKEELKEKKVEISSLSKQLTD 1378

Query: 75   L---LMESVNFS--PANLSSTGSRY-------LNALVDSAVALETKDTSLASFIPAVNDL 122
            L   L  S++ S   A +SS   +Y       L+ + D +  ++T      S +  V+D 
Sbjct: 1379 LNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDW 1438

Query: 123  TSDLFRTKSKSE-----------EIKIEL-----EKLEKNLTATLVLEKCLQE----DVK 162
            ++     K K++           E++I+L     E  EK+    L+ E+  Q+    D  
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCL 1498

Query: 163  KAELHLSTERAKVDNRRQNMDFLKAKSEEFR------------FGIKAAEEQLSARGMDA 210
            K E  +  +++K++ +  N++  + KS+  R              I++  E L       
Sbjct: 1499 KGE--MEDDKSKMEKKESNLE-TELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK 1555

Query: 211  SLSHQSLV------------------ALSEKLARLKQQTIPLKKKLESYLDLMPNPSLA- 251
             + H+ LV                     EK+  L+ Q   +K +LE+    + + +L+ 
Sbjct: 1556 DIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSV 1615

Query: 252  QVKIEEAKRELDSIEAE 268
            + K EE K   D +E+E
Sbjct: 1616 KSKEEELKALEDRLESE 1632



 Score = 34.7 bits (78), Expect = 0.094
 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 7/118 (5%)

Query: 108  KDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELH 167
            +DT+L      +   ++ +        ++K  LEKLE +L  +L     LQE + + ++ 
Sbjct: 1104 QDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKML 1163

Query: 168  LSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLA 225
               ++ KV         LK   EEF+  +K++ E+ +    D SL  +    LSE+LA
Sbjct: 1164 AEEDKRKVSELTSK---LKTTDEEFQ-SLKSSHEKSNKSLEDKSLEFKK---LSEELA 1214



 Score = 32.3 bits (72), Expect = 0.47
 Identities = 36/150 (24%), Positives = 61/150 (40%), Gaps = 27/150 (18%)

Query: 130  KSKSEEIKIELEKLEKNLTATLV----------------LEKCLQEDVKKA-ELHLSTER 172
            + + E+IK E E LE    +TL                 LE  ++E + KA E+      
Sbjct: 1973 QEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 2032

Query: 173  AKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTI 232
            +  +   Q +  +  K ++ +   K  EE L AR  +          ++ K+  L+ Q  
Sbjct: 2033 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEE----------MTAKVRDLQTQLE 2082

Query: 233  PLKKKLESYLDLMPNPSLAQVKIEEAKREL 262
             L+KK +  L+   NP    V I E + +L
Sbjct: 2083 ELQKKYQQKLEQEENPGNDNVTIMELQTQL 2112


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 53/235 (22%), Positives = 96/235 (40%), Gaps = 33/235 (14%)

Query: 59   KQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPA 118
            K+K +  E+  + L DL ME                +N L  +   LE +   L   +  
Sbjct: 998  KEKKALQEAHQQTLDDLQMEEDK-------------VNTLTKAKTKLEQQVDDLEGSLEQ 1044

Query: 119  VNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNR 178
               L  DL R K K E    +L+  +++   T   ++ L E +KK E  +S  + K+++ 
Sbjct: 1045 EKKLCMDLERAKRKLEG---DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDE 1101

Query: 179  RQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQ-------- 230
            +     L+ K +E +  I+  EE++ A     + + +    LS +L  + ++        
Sbjct: 1102 QALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161

Query: 231  --TIPLKKKLESYLDLMPNPSLAQVKIEEA------KRELDSIEAELTRRVDMME 277
               I + KK E+    M           EA      K+  DS+ AEL  ++D ++
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSV-AELGEQIDSLQ 1215



 Score = 36.6 bits (83), Expect = 0.025
 Identities = 42/225 (18%), Positives = 95/225 (42%), Gaps = 13/225 (5%)

Query: 56   EDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASF 115
            +DLK++ +  E  A  +Q   +E +  S              L+D++  ++   T   S 
Sbjct: 1669 DDLKEQLAMVERRANLMQ-AEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSL 1727

Query: 116  IPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAE---LHLSTER 172
            I     L +D+ + + + E+I  E    E+     +     + E++KK +    HL   +
Sbjct: 1728 INTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787

Query: 173  AKVDNRRQNMDFLKAKSEEFRF-GIKAAEEQLSAR------GMDASLSH--QSLVALSEK 223
              ++   +++     ++E+    G K   ++L AR       +++   H  +++  L + 
Sbjct: 1788 KNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKH 1847

Query: 224  LARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
              R+K+ T   ++  ++ L L       Q K++  KR+ +  E +
Sbjct: 1848 ERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892



 Score = 33.5 bits (75), Expect = 0.21
 Identities = 47/217 (21%), Positives = 84/217 (38%), Gaps = 26/217 (11%)

Query: 56   EDLKQKASEYESEAKYLQD---LLMESVNFSPANLSSTGSRYLNA------LVDSAVALE 106
            E  K++ ++ E++ K L++    LM+  N     + +      +A      L+ + + LE
Sbjct: 861  EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLE 920

Query: 107  TKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAEL 166
             K   +        ++ ++L   K K E+   EL+K   +L  TL           K E 
Sbjct: 921  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA----------KVEK 970

Query: 167  HLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLAR 226
                   KV N  + M  L     +     KA +E       D  +    +  L++   +
Sbjct: 971  EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTK 1030

Query: 227  LKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELD 263
            L+QQ   L+  LE    L        + +E AKR+L+
Sbjct: 1031 LEQQVDDLEGSLEQEKKLC-------MDLERAKRKLE 1060



 Score = 28.1 bits (61), Expect = 8.8
 Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 4/111 (3%)

Query: 157  LQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQS 216
            LQ   +K E   S  + ++++   NM+ +      F    +  E+QLS          + 
Sbjct: 1214 LQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRL 1273

Query: 217  LVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQ----VKIEEAKRELD 263
            +  LS + ARL  ++    ++L+    ++   S  +     +IEE KR+L+
Sbjct: 1274 INELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLE 1324


>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
          Length = 715

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 20/156 (12%)

Query: 122 LTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQN 181
           L S++ R + K+     E EKL ++L + +  ++ L+ +VK  +  L   +   D  +Q 
Sbjct: 235 LASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQE 294

Query: 182 MDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESY 241
           +  LK  S E    +KA+++ ++        S     +  EK+A L +  + +    E  
Sbjct: 295 VSLLKKSSSELEKSLKASQDAVTT-------SQSQYFSFREKIAALLRGRLSMTGSTED- 346

Query: 242 LDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
                        I E  RE+DS E    R V  +E
Sbjct: 347 ------------TILEKIREMDSREESRDRMVSQLE 370


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 53/231 (22%), Positives = 100/231 (43%), Gaps = 9/231 (3%)

Query: 54   VIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGS---RYLNALVDSAVALETKDT 110
            ++E+LK+   E + + K +++LL E+     AN   T     + + AL +    ++ +  
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 853

Query: 111  SLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELH--- 167
               S    V +L + L   + +   +K  LE+ EK+L  T    + LQE+ +  + H   
Sbjct: 854  QQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQE 913

Query: 168  LSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARL 227
            ++    K  +     + L+   +E    +K  E  L  R  D S   Q L  + ++    
Sbjct: 914  VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973

Query: 228  KQQTIPLKKK-LESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
            K Q   LK++  +      P+  L +V I E ++E+  +  EL    D +E
Sbjct: 974  KSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVE 1023



 Score = 32.0 bits (71), Expect = 0.61
 Identities = 29/172 (16%), Positives = 75/172 (43%), Gaps = 6/172 (3%)

Query: 105  LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKA 164
            +++  TS    +  +     D+   + + E +++ELEK E   +  +   + L++ + + 
Sbjct: 1178 MQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTEL 1237

Query: 165  ELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKL 224
            +  L    ++   + + ++ LKA+  E    ++  + +      D   + QSL  +  K+
Sbjct: 1238 QKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1297

Query: 225  ARLKQQTIPLKK-----KLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTR 271
             +    T  ++      + ES      + SL Q  + + ++ L ++  +LT+
Sbjct: 1298 VKAAGDTTVIENSDVSPETESSEKETMSVSLNQT-VTQLQQLLQAVNQQLTK 1348


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 53/231 (22%), Positives = 100/231 (43%), Gaps = 9/231 (3%)

Query: 54   VIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGS---RYLNALVDSAVALETKDT 110
            ++E+LK+   E + + K +++LL E+     AN   T     + + AL +    ++ +  
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 853

Query: 111  SLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELH--- 167
               S    V +L + L   + +   +K  LE+ EK+L  T    + LQE+ +  + H   
Sbjct: 854  QQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQE 913

Query: 168  LSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARL 227
            ++    K  +     + L+   +E    +K  E  L  R  D S   Q L  + ++    
Sbjct: 914  VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973

Query: 228  KQQTIPLKKK-LESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
            K Q   LK++  +      P+  L +V I E ++E+  +  EL    D +E
Sbjct: 974  KSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVE 1023


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 53/231 (22%), Positives = 100/231 (43%), Gaps = 9/231 (3%)

Query: 54   VIEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGS---RYLNALVDSAVALETKDT 110
            ++E+LK+   E + + K +++LL E+     AN   T     + + AL +    ++ +  
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELL-EAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 853

Query: 111  SLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELH--- 167
               S    V +L + L   + +   +K  LE+ EK+L  T    + LQE+ +  + H   
Sbjct: 854  QQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQE 913

Query: 168  LSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARL 227
            ++    K  +     + L+   +E    +K  E  L  R  D S   Q L  + ++    
Sbjct: 914  VAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLF 973

Query: 228  KQQTIPLKKK-LESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
            K Q   LK++  +      P+  L +V I E ++E+  +  EL    D +E
Sbjct: 974  KSQIEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSLKDAVE 1023



 Score = 32.0 bits (71), Expect = 0.61
 Identities = 29/172 (16%), Positives = 75/172 (43%), Gaps = 6/172 (3%)

Query: 105  LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKA 164
            +++  TS    +  +     D+   + + E +++ELEK E   +  +   + L++ + + 
Sbjct: 1178 MQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTEL 1237

Query: 165  ELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKL 224
            +  L    ++   + + ++ LKA+  E    ++  + +      D   + QSL  +  K+
Sbjct: 1238 QKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1297

Query: 225  ARLKQQTIPLKK-----KLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTR 271
             +    T  ++      + ES      + SL Q  + + ++ L ++  +LT+
Sbjct: 1298 VKAAGDTTVIENSDVSPETESSEKETMSVSLNQT-VTQLQQLLQAVNQQLTK 1348


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 18/205 (8%)

Query: 87   LSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKN 146
            L    +R +  L      LE +   LA  + A  +L ++   T+ +    K ELE +   
Sbjct: 892  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 951

Query: 147  LTATLVLE-----------KCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFG 195
            L A +  E           K LQ+ +++ E HL  E       +      +AK ++F   
Sbjct: 952  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1011

Query: 196  IKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKK---KLESYL----DLMPNP 248
            +   E+Q S    +  L    L   S + A  +++   L K   K E+ +    D +   
Sbjct: 1012 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1071

Query: 249  SLAQVKIEEAKRELDSIEAELTRRV 273
               + ++E+ KR LD   +EL  ++
Sbjct: 1072 EKGRQELEKLKRRLDGESSELQEQM 1096



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 50/246 (20%), Positives = 93/246 (37%), Gaps = 28/246 (11%)

Query: 42   ERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNF---SPANLSSTGSRYLNAL 98
            E  R    +++    + +++    E+E   LQ+ L  S      +  +         N  
Sbjct: 1687 EETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGN 1746

Query: 99   VDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKL---EKNLTATLVLEK 155
            +  A  LE K          +  L  +L   +S SE +     KL    ++LT  L  E+
Sbjct: 1747 LSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAER 1802

Query: 156  CLQEDVKKAELHLSTERAKVDNR----------RQNMDFLKAKSEEFRFGIKAAEEQLSA 205
                  +     L  +  ++  R          R  M     +S+     +  AEEQL  
Sbjct: 1803 SFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK-----LAQAEEQLEQ 1857

Query: 206  RGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSI 265
               +  LS + LV  +EK  RLK+  + ++++      L        +++++ KR+L+  
Sbjct: 1858 ETRERILSGK-LVRRAEK--RLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1914

Query: 266  EAELTR 271
            E E +R
Sbjct: 1915 EEEASR 1920


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 18/205 (8%)

Query: 87   LSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKN 146
            L    +R +  L      LE +   LA  + A  +L ++   T+ +    K ELE +   
Sbjct: 884  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943

Query: 147  LTATLVLE-----------KCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFG 195
            L A +  E           K LQ+ +++ E HL  E       +      +AK ++F   
Sbjct: 944  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003

Query: 196  IKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKK---KLESYL----DLMPNP 248
            +   E+Q S    +  L    L   S + A  +++   L K   K E+ +    D +   
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 249  SLAQVKIEEAKRELDSIEAELTRRV 273
               + ++E+ KR LD   +EL  ++
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQM 1088



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 50/246 (20%), Positives = 93/246 (37%), Gaps = 28/246 (11%)

Query: 42   ERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNF---SPANLSSTGSRYLNAL 98
            E  R    +++    + +++    E+E   LQ+ L  S      +  +         N  
Sbjct: 1679 EETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGN 1738

Query: 99   VDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKL---EKNLTATLVLEK 155
            +  A  LE K          +  L  +L   +S SE +     KL    ++LT  L  E+
Sbjct: 1739 LSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAER 1794

Query: 156  CLQEDVKKAELHLSTERAKVDNR----------RQNMDFLKAKSEEFRFGIKAAEEQLSA 205
                  +     L  +  ++  R          R  M     +S+     +  AEEQL  
Sbjct: 1795 SFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK-----LAQAEEQLEQ 1849

Query: 206  RGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSI 265
               +  LS + LV  +EK  RLK+  + ++++      L        +++++ KR+L+  
Sbjct: 1850 ETRERILSGK-LVRRAEK--RLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1906

Query: 266  EAELTR 271
            E E +R
Sbjct: 1907 EEEASR 1912


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 18/205 (8%)

Query: 87   LSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKN 146
            L    +R +  L      LE +   LA  + A  +L ++   T+ +    K ELE +   
Sbjct: 925  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 984

Query: 147  LTATLVLE-----------KCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFG 195
            L A +  E           K LQ+ +++ E HL  E       +      +AK ++F   
Sbjct: 985  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1044

Query: 196  IKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKK---KLESYL----DLMPNP 248
            +   E+Q S    +  L    L   S + A  +++   L K   K E+ +    D +   
Sbjct: 1045 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1104

Query: 249  SLAQVKIEEAKRELDSIEAELTRRV 273
               + ++E+ KR LD   +EL  ++
Sbjct: 1105 EKGRQELEKLKRRLDGESSELQEQM 1129



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 50/246 (20%), Positives = 93/246 (37%), Gaps = 28/246 (11%)

Query: 42   ERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNF---SPANLSSTGSRYLNAL 98
            E  R    +++    + +++    E+E   LQ+ L  S      +  +         N  
Sbjct: 1720 EETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGN 1779

Query: 99   VDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKL---EKNLTATLVLEK 155
            +  A  LE K          +  L  +L   +S SE +     KL    ++LT  L  E+
Sbjct: 1780 LSKAAILEEK----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAER 1835

Query: 156  CLQEDVKKAELHLSTERAKVDNR----------RQNMDFLKAKSEEFRFGIKAAEEQLSA 205
                  +     L  +  ++  R          R  M     +S+     +  AEEQL  
Sbjct: 1836 SFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK-----LAQAEEQLEQ 1890

Query: 206  RGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSI 265
               +  LS + LV  +EK  RLK+  + ++++      L        +++++ KR+L+  
Sbjct: 1891 ETRERILSGK-LVRRAEK--RLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1947

Query: 266  EAELTR 271
            E E +R
Sbjct: 1948 EEEASR 1953


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 20/180 (11%)

Query: 98   LVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCL 157
            L+ S + LE +   L+  +    ++ S+L     K E+   EL+K   +L   LV     
Sbjct: 920  LIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLV----- 974

Query: 158  QEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSL 217
                 K+E    T   KV N  + ++FL     +     K  +E       D  +  + L
Sbjct: 975  -----KSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKL 1029

Query: 218  VALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
             +LS+   +L+QQ   L+  LE       N           +REL  +E  L    + ME
Sbjct: 1030 SSLSKANLKLEQQVDELEGALEQERKARMN----------CERELHKLEGNLKLNRESME 1079



 Score = 35.0 bits (79), Expect = 0.072
 Identities = 49/198 (24%), Positives = 76/198 (38%), Gaps = 18/198 (9%)

Query: 85   ANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEI-KIELEKL 143
            A L  T       + D    LE + T+ A       DLT DL     + EE+    L +L
Sbjct: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173

Query: 144  EKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRR-----------QNMDFLKAKSEEF 192
            E         +K L  D+++A LH  T  A +  R            +N+  +K K E+ 
Sbjct: 1174 EITKKQETKFQK-LHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKD 1232

Query: 193  RFGIKAAEEQLSARGMD---ASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPS 249
            +  ++   + L  R      A  + + L  L E+  RL + T  L K  +   DL    +
Sbjct: 1233 KSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEE--RLHEATAKLDKVTQLANDLAAQKT 1290

Query: 250  LAQVKIEEAKRELDSIEA 267
                +  E  R L+  EA
Sbjct: 1291 KLWSESGEFLRRLEEKEA 1308



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 32/164 (19%)

Query: 107  TKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAE- 165
            T++TSL S       L +D+ R + ++EE+  E +  E+      +    L E++KK + 
Sbjct: 1730 TQNTSLLS---QKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQD 1786

Query: 166  --LHLSTERAKVD-------------------NRRQNMDFLKAKSEEFRFGI-----KAA 199
               HL   R  ++                     R+ +  L+++  E    +     ++A
Sbjct: 1787 TIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSA 1846

Query: 200  EEQLSARGMDASLSHQSLVALSEK--LARLKQQTIPLKKKLESY 241
            E Q  AR ++  +   +  A  +K  L+R++ Q   L+ K+++Y
Sbjct: 1847 EAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNY 1890


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 65/279 (23%), Positives = 118/279 (42%), Gaps = 32/279 (11%)

Query: 16   KKIFGDH---PIPQYEVNPRTTEILHHL-SERNRVRDRDVYLVI-----EDLKQKASEYE 66
            KK+ GD     I     N +  E L HL S + +++D  ++L       EDLK++ +  E
Sbjct: 1617 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 1676

Query: 67   SEAKYLQDLLMESVNFSPANLSSTG-SRYL--NALVDSAVALETKDTSLASFIPAVNDLT 123
              A    +LL   V    A L  T  +R L    L+DS   ++   T   S I     L 
Sbjct: 1677 RRA----NLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLE 1732

Query: 124  SDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAE---LHLSTERAKVDNRRQ 180
            +DL + +S+ E+   +    E+     +     + E++KK +    HL  ER K +  + 
Sbjct: 1733 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHL--ERMKKNLEQT 1790

Query: 181  NMDFLKAKSEEFRFGIKAAEEQLS-----ARGMDASL------SHQSLVALSEKLARLKQ 229
              D      E  +  +K  ++Q+       R ++  L      + +S+  L +   R+K+
Sbjct: 1791 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 1850

Query: 230  QTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
             T   ++  ++ L L       QVK++  KR+ +  + +
Sbjct: 1851 LTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQ 1889



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 53/239 (22%), Positives = 97/239 (40%), Gaps = 36/239 (15%)

Query: 57   DLKQKASEYESEAKYLQDLL------MESVNFSPANLSSTGSRYLNALVDSAVALETKDT 110
            D  Q+  E E   K L   L      +E+VN   A+L  T  R    + D  V +E  ++
Sbjct: 1379 DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS 1438

Query: 111  SLASFIPAVNDLTSDLFRTKSKSEEIKIELE---KLEKNLTATL-----VLEKCLQ--ED 160
              A+      +    L   K+K EE + ELE   K  ++L+  L       E+ L   E 
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLET 1498

Query: 161  VKKAELHLSTERAKVDNR--RQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLV 218
            VK+   +L  E A +  +         + +    +  ++ A+ QL+    +A+L H+   
Sbjct: 1499 VKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE--- 1555

Query: 219  ALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
                K+ R++ +   +K +++              KI E   E++ ++    R V+ M+
Sbjct: 1556 --EAKILRIQLELTQVKSEIDR-------------KIAEKDEEIEQLKRNYQRTVETMQ 1599



 Score = 35.8 bits (81), Expect = 0.042
 Identities = 66/264 (25%), Positives = 113/264 (42%), Gaps = 47/264 (17%)

Query: 55   IEDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLAS 114
            I+DL+   ++ E E K+  +  ++++    + L  T ++    L     AL+        
Sbjct: 955  IDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAK----LTREKKALQEAHQQALD 1009

Query: 115  FIPAVNDLTSDLFRTKSKSEEIKIELE---KLEKNLTATLVLEKC-LQEDVKKAE---LH 167
             + A  D  + L +TKSK E+   +LE   + EK L   L   K  L+ D+K A+   L 
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069

Query: 168  LSTERAKVDNRRQNMDF------------------LKAKSEEFRFGIKAAEEQLSA-RGM 208
            L  ++ ++D R +  DF                   + K +E +  I+  EE++ A R  
Sbjct: 1070 LENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERAT 1129

Query: 209  DASLSHQ------SLVALSEKLAR---LKQQTIPLKKKLES-YLDLMPNPSLAQVKIEE- 257
             A    Q       L  LSE+L     +    I L KK E+ +L L  +   A ++ E  
Sbjct: 1130 RAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAM 1189

Query: 258  ----AKRELDSIEAELTRRVDMME 277
                 K+  DS+ AEL  ++D ++
Sbjct: 1190 VAALRKKHADSV-AELGEQIDNLQ 1212



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 46/214 (21%), Positives = 83/214 (38%), Gaps = 26/214 (12%)

Query: 59   KQKASEYESEAKYLQDLLMESV---NFSPANLSSTGSRYLNA------LVDSAVALETKD 109
            K + ++ E++ K L++ L+  V   N     + +     L+A      L+ +   LE K 
Sbjct: 861  KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKI 920

Query: 110  TSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLS 169
              +        ++ ++L   K K E+   EL+K   +L  TL           K E    
Sbjct: 921  KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA----------KVEKEKH 970

Query: 170  TERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQ 229
                KV N  + +  L     +     KA +E       D       + +L++  ++L+Q
Sbjct: 971  ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQ 1030

Query: 230  QTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELD 263
            Q   L+  LE    L       +V +E  KR+L+
Sbjct: 1031 QVEDLESSLEQEKKL-------RVDLERNKRKLE 1057


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 52/242 (21%), Positives = 94/242 (38%), Gaps = 40/242 (16%)

Query: 60  QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAV 119
           QK+  ++ + +  Q+L ++     PA+     S       +S    +  D  L      +
Sbjct: 39  QKSQRFKQQKESKQNLNVDKDTTLPASARKVKSS------ESKKESQKNDKDLKILEKEI 92

Query: 120 NDLTSDLFRTKSKSEEIKIELEKLEKNLTATL-----------VLEKCLQEDVKKAEL-- 166
             L  +      + ++++ ELEK+E  L A L            LEK L E  +  EL  
Sbjct: 93  RVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLK 152

Query: 167 -------------HLSTERAKVDNRRQ-NMDFLKAKSEEFRFGIKAAEEQLSARGMDASL 212
                         LS E  K+ N+R+  M  + AK E     ++  +  L         
Sbjct: 153 SKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEE------- 205

Query: 213 SHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRR 272
           S   +  L  KL  ++++ I  K + E  L+ +   S A  ++E+ K ++  +E  L  +
Sbjct: 206 SQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEK 265

Query: 273 VD 274
            D
Sbjct: 266 ND 267



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/216 (25%), Positives = 92/216 (42%), Gaps = 24/216 (11%)

Query: 55  IEDLK-QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSL- 112
           IEDLK + +S  E  AK  ++   E V        S+   Y+  L+D       K+T + 
Sbjct: 471 IEDLKLENSSLQEKAAKAGKNA--EDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 528

Query: 113 ---ASFIPAVNDLTSDLFRTKSKSEEIKIELE-----KLEK-NLTATLVLEKCLQEDVKK 163
               SF+  + DL + L   K + E+ + +LE     K EK N TA L       E++ K
Sbjct: 529 EITVSFLQKITDLQNQL---KQQEEDFRKQLEDEEGRKAEKENTTAELT------EEINK 579

Query: 164 AELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSA-RGMDASL-SHQSLVALS 221
             L       K    +  +D  + + +       AA+EQL+  R   A L  HQ+L    
Sbjct: 580 WRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKI 639

Query: 222 EKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEE 257
           + + +LK +   LK ++      +     ++ K++E
Sbjct: 640 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQE 675


>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
          Length = 2649

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/171 (21%), Positives = 87/171 (50%), Gaps = 18/171 (10%)

Query: 123  TSDLFRTKSKSEE-IKIELEKLEKNLTATLVL-----EKCLQEDV-----KKAELHLSTE 171
            T++    ++K+E+  + +++ LE++L  +  L     +KC Q+++     KK   +L+ E
Sbjct: 1628 TNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAE 1687

Query: 172  --RAKVDNRR--QNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARL 227
               +K + RR  Q +   +A+ +E    +K  +++L  + ++  ++H+ +V   E+  + 
Sbjct: 1688 LNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKF 1747

Query: 228  KQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL 278
            KQ     +KK+E    LM +  + +  I   + +  S++ E +R  +  +L
Sbjct: 1748 KQSAEEFRKKMEK---LMESKVITENDISGIRLDFVSLQQENSRAQENAKL 1795



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 52/257 (20%), Positives = 104/257 (40%), Gaps = 36/257 (14%)

Query: 56   EDLKQKASEYES-EAKYLQDLLMESVNFSPANLSSTGS----RYLNALVDSA-------- 102
            E+LKQ+  E  +   K  QD+   +   +   L  T S    R L   +D          
Sbjct: 1362 EELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLK 1421

Query: 103  VALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIE---LEKLEKNLTATLVLEKC--- 156
            + LE KD +   +   + +L   L +T  K+EE   E   L+K+++N    L LE     
Sbjct: 1422 LELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQ--LELESLNHE 1479

Query: 157  ---LQEDVKK-------AELHLSTERAKVDNRR-----QNMDFLKAKSEEFRFGIKAAEE 201
               LQ +V +       AE ++    +++ + R     + +   + KS+  +   + + E
Sbjct: 1480 KGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHE 1539

Query: 202  QLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRE 261
            QL         ++  +  L+E+L +  +    LK+K+E          L   +I+     
Sbjct: 1540 QLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESEN 1599

Query: 262  LDSIEAELTRRVDMMEL 278
            +   +  + +R + +++
Sbjct: 1600 IVLEKQTIQQRCEALKI 1616



 Score = 28.5 bits (62), Expect = 6.8
 Identities = 36/170 (21%), Positives = 63/170 (37%), Gaps = 35/170 (20%)

Query: 105  LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLT-ATLVLEKCLQEDVK- 162
            L+ KD SL       N L  +L R +   EE+   ++++EK+L     V EK L+E  K 
Sbjct: 1256 LKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKI 1315

Query: 163  ---------------------------------KAELHLSTERAKVDNRRQNMDFLKAKS 189
                                                L    ++ K +  +Q +D L A +
Sbjct: 1316 ELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAAN 1375

Query: 190  EEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLE 239
             +    ++    +L+A  ++ + S +    L +KL         LK +LE
Sbjct: 1376 RKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELE 1425


>gi|14165274 golgi-associated microtubule-binding protein HOOK3
           [Homo sapiens]
          Length = 718

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 20/241 (8%)

Query: 32  RTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQ---DLLMESVNFSPANLS 88
           +  E+ + LSE ++  D+ +    + LK+K    + E   L+   D L E++       +
Sbjct: 374 QVVELQNRLSEESKKADK-LDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQA 432

Query: 89  STGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLT 148
             G      L+    + E+ D+  A  +    ++   L R + +++ +K+  E  +    
Sbjct: 433 QEGQLTTQGLMPLG-SQESSDSLAAEIVTP--EIREKLIRLQHENKMLKLNQEGSDNEKI 489

Query: 149 ATLVLEKCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGM 208
           A L   + L +D    +  L TE     NR  N   L+ +S+     ++  ++ L  +G 
Sbjct: 490 ALL---QSLLDDANLRKNELETE-----NRLVNQRLLEVQSQ-----VEELQKSLQDQGS 536

Query: 209 DASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
            A  S      L E L +L +    L+KK     DL P  + + +KIEE +  L   E E
Sbjct: 537 KAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEE 596

Query: 269 L 269
           +
Sbjct: 597 M 597



 Score = 32.0 bits (71), Expect = 0.61
 Identities = 49/243 (20%), Positives = 97/243 (39%), Gaps = 65/243 (26%)

Query: 32  RTTEILHH-LSERNRVRDR--DVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSPANLS 88
           +TTE L+  LS +  +  R  ++ + +  L+++ S   +E + L + L +S +    N S
Sbjct: 180 KTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPN-S 238

Query: 89  STGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLT 148
             G R+L         L+T+          +  L  + FR ++  ++ +I  E+LEK ++
Sbjct: 239 PAGRRHLQ--------LQTQ----------LEQLQEETFRLEAAKDDYRIRCEELEKEIS 280

Query: 149 ATLVLEKCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGM 208
                      ++++    L+T   +  + +  +D L+  S+                  
Sbjct: 281 -----------ELRQQNDELTTLADEAQSLKDEIDVLRHSSD------------------ 311

Query: 209 DASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
                         K+++L+ Q    KKKLE   DL     L + K     +   S+E E
Sbjct: 312 --------------KVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEE 357

Query: 269 LTR 271
           L +
Sbjct: 358 LRK 360


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 47/226 (20%), Positives = 102/226 (45%), Gaps = 32/226 (14%)

Query: 48  DRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNF-SPANLSSTGSRYLNALVDS----A 102
           +R + L +  L Q+  E E   K LQ    E             G+  L A V++     
Sbjct: 328 NRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 387

Query: 103 VALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVK 162
           + +E KD  +        +L   L   +  S+E+++E+EKL+K ++    LE+   +   
Sbjct: 388 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447

Query: 163 K-AELHLSTERAK--VDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVA 219
           +  +LHL+ E+ K    +    ++ +K++ +E    ++ +E +L           ++ ++
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELEVVKSRVKE----LECSESRL----------EKAELS 493

Query: 220 LSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSI 265
           L + L +LK  T+ L  + ++ ++          KI++ +R++D +
Sbjct: 494 LKDDLTKLKSFTVMLVDERKNMME----------KIKQEERKVDGL 529



 Score = 28.5 bits (62), Expect = 6.8
 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 10/157 (6%)

Query: 119 VNDLTSDLFRTKSKSEEIKIELEKLEKNLTATL--VLEKCLQEDVKKAELHLSTERAKVD 176
           V D+T  L     K  ++K E+E+   NLT     ++ K   E+ K +EL  S     VD
Sbjct: 540 VMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCS-----VD 594

Query: 177 NRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSL--VALSEKLARLKQQTIPL 234
             ++ +D ++    E   G      +L+    D  +   +L    L ++L +L+     L
Sbjct: 595 LLKKRLDGIEEVEREITRGRSRKGSELTC-PEDNKIKELTLEIERLKKRLQQLEVVEGDL 653

Query: 235 KKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTR 271
            K  + Y  L       Q K     ++L+ I+ ++ +
Sbjct: 654 MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAK 690


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 25/165 (15%)

Query: 105 LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCL---QEDV 161
           +E KD  L        DL   L R   +S++ K+E+EKL K + A   LE      +++ 
Sbjct: 382 MEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQEC 441

Query: 162 KKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALS 221
              + +L  ER       Q ++ LK + +E    ++A E +L           ++   L 
Sbjct: 442 YSLKCNLEKERMTTKQLSQELESLKVRIKE----LEAIESRL----------EKTEFTLK 487

Query: 222 EKLARLKQQTI-------PLKKKLESYLDLMPNPSLAQVKIEEAK 259
           E L +LK  T+        + +KL+   D +   S +Q+++E+ K
Sbjct: 488 EDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAAS-SQLQVEQNK 531


>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
           sapiens]
          Length = 893

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 25/165 (15%)

Query: 105 LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCL---QEDV 161
           +E KD  L        DL   L R   +S++ K+E+EKL K + A   LE      +++ 
Sbjct: 142 MEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQEC 201

Query: 162 KKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALS 221
              + +L  ER       Q ++ LK + +E    ++A E +L           ++   L 
Sbjct: 202 YSLKCNLEKERMTTKQLSQELESLKVRIKE----LEAIESRL----------EKTEFTLK 247

Query: 222 EKLARLKQQTI-------PLKKKLESYLDLMPNPSLAQVKIEEAK 259
           E L +LK  T+        + +KL+   D +   S +Q+++E+ K
Sbjct: 248 EDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAAS-SQLQVEQNK 291


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 25/165 (15%)

Query: 105 LETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCL---QEDV 161
           +E KD  L        DL   L R   +S++ K+E+EKL K + A   LE      +++ 
Sbjct: 382 MEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQEC 441

Query: 162 KKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALS 221
              + +L  ER       Q ++ LK + +E    ++A E +L           ++   L 
Sbjct: 442 YSLKCNLEKERMTTKQLSQELESLKVRIKE----LEAIESRL----------EKTEFTLK 487

Query: 222 EKLARLKQQTI-------PLKKKLESYLDLMPNPSLAQVKIEEAK 259
           E L +LK  T+        + +KL+   D +   S +Q+++E+ K
Sbjct: 488 EDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAAS-SQLQVEQNK 531


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 69/290 (23%), Positives = 113/290 (38%), Gaps = 42/290 (14%)

Query: 5    EERETQVAAWLKKIFGDHPIPQYE--VNPRTTEILHHLSERNRVRDR------DVYLVIE 56
            EE +  V A  KK    H I + E  +     E+  +  E NR++++      D+    E
Sbjct: 1022 EECKEIVKASSKK---SHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKE 1078

Query: 57   DLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFI 116
             L Q+  E   E     D+ ++ V          G R L+ L       + K   L + +
Sbjct: 1079 TLIQQLKEELQEKNVTLDVQIQHV--------VEGKRALSELTQGVTCYKAKIKELETIL 1130

Query: 117  PAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKA------ELHLST 170
                   S   + +    E +  + KLE+NL      ++ LQ+ VK        EL L  
Sbjct: 1131 ETQKVECSHSAKLEQDILEKESIILKLERNLKE---FQEHLQDSVKNTKDLNVKELKLKE 1187

Query: 171  ERAKVDNRRQNMD-FLKAKSEEFRFGIKAAE---EQLSARGM-------DASLSHQSLVA 219
            E  ++ N  Q+M   L+ K EE     +  E   E+LSA          D     +    
Sbjct: 1188 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1247

Query: 220  LSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAEL 269
            L EKL   K+Q   ++K++    D      L ++KI E +++ +    EL
Sbjct: 1248 LKEKLTDAKKQIKQVQKEVSVMRD---EDKLLRIKINELEKKKNQCSQEL 1294


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 62/297 (20%), Positives = 124/297 (41%), Gaps = 33/297 (11%)

Query: 2    EPQEERETQVAAWLKKIFGD-----HPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIE 56
            E +EE   ++ A  +K+  +       I   E+     E   H +E N+V++    +   
Sbjct: 933  EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMA-- 989

Query: 57   DLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFI 116
             L +  ++   E K LQ+   ++++   A         +N L  + + LE +   L   +
Sbjct: 990  GLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-----VNTLTKAKIKLEQQVDDLEGSL 1044

Query: 117  PAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVD 176
                 L  DL R K K E    +L+  ++++      ++ L E +KK E  +S  ++K++
Sbjct: 1045 EQEKKLRMDLERAKRKLEG---DLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE 1101

Query: 177  NRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQ------ 230
            + +     L+ K +E +  I+  EE++ A     + + +    LS +L  + ++      
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161

Query: 231  ----TIPLKKKLESYLDLMPNPSLAQVKIEEA------KRELDSIEAELTRRVDMME 277
                 I + KK E+    M           EA      K+  DS+ AEL  ++D ++
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV-AELGEQIDNLQ 1217



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 60/276 (21%), Positives = 113/276 (40%), Gaps = 50/276 (18%)

Query: 9    TQVAAWLKKIFGDHPIPQYEVNP-RTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYES 67
            T+VA W  K         YE +  + TE L    ++   R +     +E +  K +  E 
Sbjct: 1372 TEVAQWRTK---------YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422

Query: 68   EAKYLQ----DLLM--ESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVND 121
              + LQ    DL++  E  N + A L      +   L +     E     L +       
Sbjct: 1423 TKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482

Query: 122  LTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQN 181
            L ++LF+ K+  EE   +LE L++         K LQ+++      L+ + A+   R   
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRE-------NKNLQQEIS----DLTEQIAEGGKRIHE 1531

Query: 182  MDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESY 241
            ++ +K + E+ +  ++AA E+      +ASL H+       K+ R++ +   +K +++  
Sbjct: 1532 LEKIKKQVEQEKCELQAALEE-----AEASLEHE-----EGKILRIQLELNQVKSEVDR- 1580

Query: 242  LDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
                        KI E   E+D ++    R V+ M+
Sbjct: 1581 ------------KIAEKDEEIDQLKRNHIRIVESMQ 1604



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 19/228 (8%)

Query: 56   EDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTG-SRYL--NALVDSAVALETKDTSL 112
            EDLK++ +  E  A  LQ  + E      A L  T  SR +    L+D++  ++   T  
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEEL----RATLEQTERSRKIAEQELLDASERVQLLHTQN 1726

Query: 113  ASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAE---LHLS 169
             S I     L +D+ + + + E+I  E    E+     +     + E++KK +    HL 
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786

Query: 170  TERAKVDNRRQNMDFLKAKSEEFRF-GIKAAEEQLSAR--------GMDASLSHQSLVAL 220
              +  ++   +++     ++E+    G K   ++L AR          +   + +++  L
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846

Query: 221  SEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
             +   R+K+ T   ++  ++ L L       Q K++  KR+ +  E +
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 62/297 (20%), Positives = 124/297 (41%), Gaps = 33/297 (11%)

Query: 2    EPQEERETQVAAWLKKIFGD-----HPIPQYEVNPRTTEILHHLSERNRVRDRDVYLVIE 56
            E +EE   ++ A  +K+  +       I   E+     E   H +E N+V++    +   
Sbjct: 933  EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMA-- 989

Query: 57   DLKQKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFI 116
             L +  ++   E K LQ+   ++++   A         +N L  + + LE +   L   +
Sbjct: 990  GLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK-----VNTLTKAKIKLEQQVDDLEGSL 1044

Query: 117  PAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVD 176
                 L  DL R K K E    +L+  ++++      ++ L E +KK E  +S  ++K++
Sbjct: 1045 EQEKKLRMDLERAKRKLEG---DLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE 1101

Query: 177  NRRQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQ------ 230
            + +     L+ K +E +  I+  EE++ A     + + +    LS +L  + ++      
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161

Query: 231  ----TIPLKKKLESYLDLMPNPSLAQVKIEEA------KRELDSIEAELTRRVDMME 277
                 I + KK E+    M           EA      K+  DS+ AEL  ++D ++
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV-AELGEQIDNLQ 1217



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 60/276 (21%), Positives = 113/276 (40%), Gaps = 50/276 (18%)

Query: 9    TQVAAWLKKIFGDHPIPQYEVNP-RTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYES 67
            T+VA W  K         YE +  + TE L    ++   R +     +E +  K +  E 
Sbjct: 1372 TEVAQWRTK---------YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422

Query: 68   EAKYLQ----DLLM--ESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAVND 121
              + LQ    DL++  E  N + A L      +   L +     E     L +       
Sbjct: 1423 TKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482

Query: 122  LTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQN 181
            L ++LF+ K+  EE   +LE L++         K LQ+++      L+ + A+   R   
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRE-------NKNLQQEIS----DLTEQIAEGGKRIHE 1531

Query: 182  MDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESY 241
            ++ +K + E+ +  ++AA E+      +ASL H+       K+ R++ +   +K +++  
Sbjct: 1532 LEKIKKQVEQEKCELQAALEE-----AEASLEHE-----EGKILRIQLELNQVKSEVDR- 1580

Query: 242  LDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMME 277
                        KI E   E+D ++    R V+ M+
Sbjct: 1581 ------------KIAEKDEEIDQLKRNHIRIVESMQ 1604



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 19/228 (8%)

Query: 56   EDLKQKASEYESEAKYLQDLLMESVNFSPANLSSTG-SRYL--NALVDSAVALETKDTSL 112
            EDLK++ +  E  A  LQ  + E      A L  T  SR +    L+D++  ++   T  
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEEL----RATLEQTERSRKIAEQELLDASERVQLLHTQN 1726

Query: 113  ASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAE---LHLS 169
             S I     L +D+ + + + E+I  E    E+     +     + E++KK +    HL 
Sbjct: 1727 TSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1786

Query: 170  TERAKVDNRRQNMDFLKAKSEEFRF-GIKAAEEQLSAR--------GMDASLSHQSLVAL 220
              +  ++   +++     ++E+    G K   ++L AR          +   + +++  L
Sbjct: 1787 RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGL 1846

Query: 221  SEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAE 268
             +   R+K+ T   ++  ++ L L       Q K++  KR+ +  E +
Sbjct: 1847 RKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
           sapiens]
          Length = 638

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/216 (25%), Positives = 92/216 (42%), Gaps = 24/216 (11%)

Query: 55  IEDLK-QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSL- 112
           IEDLK + +S  E  AK  ++   E V        S+   Y+  L+D       K+T + 
Sbjct: 384 IEDLKLENSSLQEKAAKAGKNA--EDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 441

Query: 113 ---ASFIPAVNDLTSDLFRTKSKSEEIKIELE-----KLEK-NLTATLVLEKCLQEDVKK 163
               SF+  + DL + L   K + E+ + +LE     K EK N TA L       E++ K
Sbjct: 442 EITVSFLQKITDLQNQL---KQQEEDFRKQLEDEEGRKAEKENTTAELT------EEINK 492

Query: 164 AELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSA-RGMDASL-SHQSLVALS 221
             L       K    +  +D  + + +       AA+EQL+  R   A L  HQ+L    
Sbjct: 493 WRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKI 552

Query: 222 EKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEE 257
           + + +LK +   LK ++      +     ++ K++E
Sbjct: 553 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQE 588



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 41/168 (24%), Positives = 69/168 (41%), Gaps = 34/168 (20%)

Query: 134 EEIKIELEKLEKNLTATL-----------VLEKCLQEDVKKAEL---------------H 167
           ++++ ELEK+E  L A L            LEK L E  +  EL                
Sbjct: 20  QDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRI 79

Query: 168 LSTERAKVDNRRQ-NMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLAR 226
           LS E  K+ N+R+  M  + AK E     ++  +  L         S   +  L  KL  
Sbjct: 80  LSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEE-------SQGKIAQLEGKLVS 132

Query: 227 LKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVD 274
           ++++ I  K + E  L+ +   S A  ++E+ K ++  +E  L  + D
Sbjct: 133 IEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 180


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
           sapiens]
          Length = 709

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/216 (25%), Positives = 92/216 (42%), Gaps = 24/216 (11%)

Query: 55  IEDLK-QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSL- 112
           IEDLK + +S  E  AK  ++   E V        S+   Y+  L+D       K+T + 
Sbjct: 455 IEDLKLENSSLQEKAAKAGKNA--EDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 512

Query: 113 ---ASFIPAVNDLTSDLFRTKSKSEEIKIELE-----KLEK-NLTATLVLEKCLQEDVKK 163
               SF+  + DL + L   K + E+ + +LE     K EK N TA L       E++ K
Sbjct: 513 EITVSFLQKITDLQNQL---KQQEEDFRKQLEDEEGRKAEKENTTAELT------EEINK 563

Query: 164 AELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSA-RGMDASL-SHQSLVALS 221
             L       K    +  +D  + + +       AA+EQL+  R   A L  HQ+L    
Sbjct: 564 WRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKI 623

Query: 222 EKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEE 257
           + + +LK +   LK ++      +     ++ K++E
Sbjct: 624 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQE 659



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 47/206 (22%), Positives = 79/206 (38%), Gaps = 34/206 (16%)

Query: 96  NALVDSAVALETKDTSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATL---- 151
           N  VD    L      + S    +  L  +      + ++++ ELEK+E  L A L    
Sbjct: 53  NLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKT 112

Query: 152 -------VLEKCLQEDVKKAEL---------------HLSTERAKVDNRRQ-NMDFLKAK 188
                   LEK L E  +  EL                LS E  K+ N+R+  M  + AK
Sbjct: 113 SLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAK 172

Query: 189 SEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNP 248
            E     ++  +  L         S   +  L  KL  ++++ I  K + E  L+ +   
Sbjct: 173 QEGMEMKLQVTQRSLEE-------SQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI 225

Query: 249 SLAQVKIEEAKRELDSIEAELTRRVD 274
           S A  ++E+ K ++  +E  L  + D
Sbjct: 226 SCASDQVEKYKLDIAQLEENLKEKND 251


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 51/242 (21%), Positives = 93/242 (38%), Gaps = 41/242 (16%)

Query: 60  QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSLASFIPAV 119
           QK+  ++ + +  Q+L ++     PA+     S         +   +  D  L      +
Sbjct: 39  QKSQRFKQQKESKQNLNVDKDTTLPASARKVKS-------SESKESQKNDKDLKILEKEI 91

Query: 120 NDLTSDLFRTKSKSEEIKIELEKLEKNLTATL-----------VLEKCLQEDVKKAEL-- 166
             L  +      + ++++ ELEK+E  L A L            LEK L E  +  EL  
Sbjct: 92  RVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLK 151

Query: 167 -------------HLSTERAKVDNRRQ-NMDFLKAKSEEFRFGIKAAEEQLSARGMDASL 212
                         LS E  K+ N+R+  M  + AK E     ++  +  L         
Sbjct: 152 SKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEE------- 204

Query: 213 SHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRR 272
           S   +  L  KL  ++++ I  K + E  L+ +   S A  ++E+ K ++  +E  L  +
Sbjct: 205 SQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEK 264

Query: 273 VD 274
            D
Sbjct: 265 ND 266



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/216 (25%), Positives = 92/216 (42%), Gaps = 24/216 (11%)

Query: 55  IEDLK-QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKDTSL- 112
           IEDLK + +S  E  AK  ++   E V        S+   Y+  L+D       K+T + 
Sbjct: 470 IEDLKLENSSLQEKAAKAGKNA--EDVQHQILATESSNQEYVRMLLDLQTKSALKETEIK 527

Query: 113 ---ASFIPAVNDLTSDLFRTKSKSEEIKIELE-----KLEK-NLTATLVLEKCLQEDVKK 163
               SF+  + DL + L   K + E+ + +LE     K EK N TA L       E++ K
Sbjct: 528 EITVSFLQKITDLQNQL---KQQEEDFRKQLEDEEGRKAEKENTTAELT------EEINK 578

Query: 164 AELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAAEEQLSA-RGMDASL-SHQSLVALS 221
             L       K    +  +D  + + +       AA+EQL+  R   A L  HQ+L    
Sbjct: 579 WRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKI 638

Query: 222 EKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEE 257
           + + +LK +   LK ++      +     ++ K++E
Sbjct: 639 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQE 674


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 53/263 (20%), Positives = 115/263 (43%), Gaps = 25/263 (9%)

Query: 35   EILHHLSERNRVRDRDVYLVIE--DLKQKASEY-----ESEAKYLQDLLMESVNFSPANL 87
            EI   + E+  ++     L IE   LK+   E      ES+ K  Q L M +VN +   +
Sbjct: 1584 EIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643

Query: 88   SSTGSRYLNALVDSAVA----LETKDTSLASFI----PAVNDLTSDLFRTKSKSEEIKIE 139
                  +L    ++       +ET++  L   +      +  +T +    +S  E +K+E
Sbjct: 1644 CEI--EHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVE 1701

Query: 140  LEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKSEEFRFGIKAA 199
             ++L++NL  T+  +   QE++K   +HL   +  +D  R  +     +    +  ++ +
Sbjct: 1702 RDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS 1761

Query: 200  EEQLSARGM----DASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKI 255
             + L A+ +    +  ++H  L    E + +L+     + +K +   ++  +   +  K+
Sbjct: 1762 NDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG---IVSEKTDKLSNMQKDLENSNAKL 1818

Query: 256  EEAKRELDSIEAEL-TRRVDMME 277
            +E  +EL + E +L T + D+ E
Sbjct: 1819 QEKIQELKANEHQLITLKKDVNE 1841



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 65/265 (24%), Positives = 112/265 (42%), Gaps = 53/265 (20%)

Query: 30   NPRTTEILHHLSERNR--VRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSPANL 87
            N R T+ILH   E  R   ++RD      DL+      E   K  +D L E       NL
Sbjct: 1667 NIRLTQILHENLEEMRSVTKERD------DLRS----VEETLKVERDQLKE-------NL 1709

Query: 88   SSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFR--TKSKSEEIKIELEKLEK 145
              T +R L          + ++  +       +  T D  R     K+ EI    + LE 
Sbjct: 1710 RETITRDLE---------KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760

Query: 146  NLTATLVLEKCLQEDVKKAELHLSTERAKVD--------------NRRQNMDFLKAKSEE 191
            +  A    +  +QE+++ A +HL  ++  +D              N +++++   AK +E
Sbjct: 1761 SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820

Query: 192  FRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLA 251
                +KA E QL     D + + + +  + +   ++K Q++ L  KLE     + N +LA
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL-SKLE-----IENLNLA 1874

Query: 252  QVKIEEAKRELDSI--EAELTRRVD 274
            Q K+ E   E+ S+  E +  RRV+
Sbjct: 1875 Q-KLHENLEEMKSVMKERDNLRRVE 1898


>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
          Length = 1037

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 63/261 (24%), Positives = 104/261 (39%), Gaps = 48/261 (18%)

Query: 24  IPQYEVNP----RTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMES 79
           IPQ   NP    R + +  H+S             +  +  +AS  +SE    +D LM+ 
Sbjct: 288 IPQLPENPPNFLRASALSEHISP------------VVVIPAEASSPDSEPVLEKDDLMD- 334

Query: 80  VNFSPANL----------SSTGSRYLNALVDSAVALETKDTSLASFIPAVNDLTSDLFRT 129
           ++ S  NL          SS  S   N    + V  + KD  +      ++ L + L   
Sbjct: 335 MDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENM 394

Query: 130 KSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRRQNMDFLKAKS 189
           K++S+ + ++L+     L A L  ++           HL  + A       + +FL+A+ 
Sbjct: 395 KTESQRVVLQLKGHVSELEADLAEQQ-----------HLRQQAA------DDCEFLRAEL 437

Query: 190 EEFRF---GIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMP 246
           +E R      + A+  LS     A  + Q    L EK + L Q    L +K       + 
Sbjct: 438 DELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVS 497

Query: 247 NPSLAQVKIEEAKREL-DSIE 266
               AQV +E  K+EL DS+E
Sbjct: 498 MARQAQVDLEREKKELEDSLE 518


>gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens]
          Length = 413

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 5/142 (3%)

Query: 55  IEDLK---QKASEYESEAKYLQDLLMESVNFSPANLSSTGSRYLNALVDSAVALETKD-- 109
           I DLK   Q ASE  S+   L DLL   V        +          +  + +  K+  
Sbjct: 134 IADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEIL 193

Query: 110 TSLASFIPAVNDLTSDLFRTKSKSEEIKIELEKLEKNLTATLVLEKCLQEDVKKAELHLS 169
           T +      +N++ SD    ++K E+ K+ELE+  K L     +  C  ++ +K E  L 
Sbjct: 194 TQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQ 253

Query: 170 TERAKVDNRRQNMDFLKAKSEE 191
            +      + QN+ +L+ + E+
Sbjct: 254 KQYDTYLEKFQNLTYLEQQLED 275


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,792,683
Number of Sequences: 37866
Number of extensions: 350907
Number of successful extensions: 2137
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 1625
Number of HSP's gapped (non-prelim): 714
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.