Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 19923967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923967 G protein-coupled receptor associated sorting
protein 2 [Homo sapiens]
         (838 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51702248 G protein-coupled receptor associated sorting protei...  1681   0.0  
gi|19923967 G protein-coupled receptor associated sorting protei...  1681   0.0  
gi|150378528 G protein-coupled receptor associated sorting prote...   631   0.0  
gi|150378489 G protein-coupled receptor associated sorting prote...   631   0.0  
gi|103472136 G protein-coupled receptor associated sorting prote...   631   0.0  
gi|216547715 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547682 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547672 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547663 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547655 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547646 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|216547639 basic helix-loop-helix domain containing, class B, ...   231   3e-60
gi|39930463 basic helix-loop-helix domain containing, class B, 9...   231   3e-60
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...   218   2e-56
gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]    172   9e-43
gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]     130   7e-30
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]    127   6e-29
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]    127   6e-29
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]     127   6e-29
gi|238776793 SVH protein isoform b [Homo sapiens]                     123   6e-28
gi|31377663 SVH protein isoform a [Homo sapiens]                      123   6e-28
gi|7662162 ALEX2 protein [Homo sapiens]                                97   5e-20
gi|29540562 ALEX2 protein [Homo sapiens]                               97   5e-20
gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo s...    88   4e-17
gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo s...    86   1e-16
gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo s...    86   1e-16
gi|238776797 SVH protein isoform e [Homo sapiens]                      86   2e-16
gi|238776799 SVH protein isoform d [Homo sapiens]                      60   1e-08
gi|238776795 SVH protein isoform c [Homo sapiens]                      60   1e-08
gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo s...    52   2e-06

>gi|51702248 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score = 1681 bits (4354), Expect = 0.0
 Identities = 838/838 (100%), Positives = 838/838 (100%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
Sbjct: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
           RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
Sbjct: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
           RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
Sbjct: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE 240
           ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
Sbjct: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE 240

Query: 241 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT 300
           ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
Sbjct: 241 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT 300

Query: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT 360
           NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
Sbjct: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT 360

Query: 361 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420
           ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
Sbjct: 361 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420

Query: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE 480
           SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
Sbjct: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE 480

Query: 481 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ 540
           ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
Sbjct: 481 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ 540

Query: 541 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE 600
           ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
Sbjct: 541 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE 600

Query: 601 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE 660
           FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
Sbjct: 601 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE 660

Query: 661 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM 720
           NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
Sbjct: 661 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM 720

Query: 721 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV 780
           SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
Sbjct: 721 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV 780

Query: 781 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838
           IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
Sbjct: 781 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838


>gi|19923967 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score = 1681 bits (4354), Expect = 0.0
 Identities = 838/838 (100%), Positives = 838/838 (100%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
Sbjct: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
           RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
Sbjct: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
           RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
Sbjct: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE 240
           ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
Sbjct: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE 240

Query: 241 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT 300
           ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
Sbjct: 241 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT 300

Query: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT 360
           NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
Sbjct: 301 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT 360

Query: 361 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420
           ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
Sbjct: 361 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420

Query: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE 480
           SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
Sbjct: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE 480

Query: 481 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ 540
           ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
Sbjct: 481 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ 540

Query: 541 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE 600
           ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
Sbjct: 541 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE 600

Query: 601 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE 660
           FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
Sbjct: 601 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE 660

Query: 661 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM 720
           NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
Sbjct: 661 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM 720

Query: 721 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV 780
           SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
Sbjct: 721 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV 780

Query: 781 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838
           IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
Sbjct: 781 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838


>gi|150378528 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  631 bits (1627), Expect = 0.0
 Identities = 367/702 (52%), Positives = 452/702 (64%), Gaps = 69/702 (9%)

Query: 200  EETNMGSWCYSRPRAREEASNESGFWSADE-----TSTASSFWTGEETSVRSWPREESNT 254
            EE  + SW +SR   + EA   S  W+ +E     T   +   T EET + SW  +E   
Sbjct: 700  EEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEA 759

Query: 255  RSRHRAKHQTNPRSRPRSKQEAYVDSW--SGSED----------------EASNPFSFWV 296
             S    + +    SRP +++   + SW  +G ED                E       W 
Sbjct: 760  ISEATDREE----SRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWF 815

Query: 297  GENTNNLFR---------PRVREEANIRSKLRTNREDC--------FESE---SEDEFYK 336
            G     + R         P+  EE  I        E          FES+    E+E   
Sbjct: 816  GAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITV 875

Query: 337  QSWVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEV 385
             SW  P EEA+ +   +  E+  +  +   +      D   V +E        P  +EE+
Sbjct: 876  GSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEM 935

Query: 386  IIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKP 441
            I+ SWFW+  +A  E G  A CES+P  EEGAI GS + AE+    ++  G+        
Sbjct: 936  IVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLA 995

Query: 442  ESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKP 500
            + E+EAI GSWFW  DEA F+ NP PV++   R   + E E + S RPQ+W+EVTV+FKP
Sbjct: 996  D-EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKP 1054

Query: 501  GLFHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQ 556
            G +  VGF S SPF  P+EA+    EM   KP+N+ LSPEGE+QESLLQPDQPSPEF FQ
Sbjct: 1055 GPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQ 1114

Query: 557  YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            YDPSYRSV+EIREHLRA+ES E ES SC+CIQCELKIGSEEFEE LLLM+KIRDPFIHEI
Sbjct: 1115 YDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEI 1174

Query: 617  SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIE 676
            SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMI MAPPYPNLN+I+
Sbjct: 1175 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQ 1234

Query: 677  TFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKF 736
            T+IC+VCEETLA+SVDS EQL+GIRM+RHLT T DYHTL+ANYMSGFLSLL T NA+T+F
Sbjct: 1235 TYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRF 1294

Query: 737  HVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKM 796
            HVLKMLLNLSEN  + K+L SA+A+S F+GLFN EETNDNIQIV+ +F+NI N IK  + 
Sbjct: 1295 HVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ET 1353

Query: 797  SLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838
               DDDF++EPLISAF + E+ AK+LQ + DNQNDPE  Q++
Sbjct: 1354 VFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN 1395



 Score =  319 bits (818), Expect = 6e-87
 Identities = 210/513 (40%), Positives = 273/513 (53%), Gaps = 94/513 (18%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           MTGAEIE  AQ KPEKK GEEV+ G E ENDVPLVVRPKVRTQA                
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA---------------- 44

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                             Q+M GARPK +++ + GA  K +  AVGGAR K+ AKAIP +
Sbjct: 45  ------------------QIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVS 86

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
           R K+EAQ WAQ  FG E +S+ E  SQTN +A PL + +S  V K+K LS DRELVN D 
Sbjct: 87  RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT 146

Query: 181 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT 238
           E+FP  +   Q G QP F   EETNMGSWC  RP +++EAS  S F   D+ S +S FW+
Sbjct: 147 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS 205

Query: 239 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV 296
           G+E + +  P  R + + RS H A  + N  SR ++ QE Y+ S SGSEDE+     FW 
Sbjct: 206 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA 265

Query: 297 GENTNNLFRPRVREEANIRSKLRTNREDCFESE--SEDEFYKQSW------------VLP 342
            + TN    P  RE+ N RS+ R+ +E   ES   SE E + +SW            +  
Sbjct: 266 RDKTNTWSGP--REDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323

Query: 343 GEEANSRFRHRDK------------------------EDPNT-------------ALKLR 365
           G+EAN+R RHR K                        E+ NT             A+   
Sbjct: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383

Query: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWA 425
             K     R KQE R EEE +IG+WFWA  E+S+   AS   ES    E+ +I GS +W 
Sbjct: 384 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEAS--IESSLQVEDESIIGSWFWT 441

Query: 426 EEKSSLGAVAREEAKPESEEEAIFGSWFWDRDE 458
           EE++S+G  A  +++P ++ E I  S F  R++
Sbjct: 442 EEEASMGTGASSKSRPRTDGERIGDSLFGAREK 474


>gi|150378489 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  631 bits (1627), Expect = 0.0
 Identities = 367/702 (52%), Positives = 452/702 (64%), Gaps = 69/702 (9%)

Query: 200  EETNMGSWCYSRPRAREEASNESGFWSADE-----TSTASSFWTGEETSVRSWPREESNT 254
            EE  + SW +SR   + EA   S  W+ +E     T   +   T EET + SW  +E   
Sbjct: 700  EEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEA 759

Query: 255  RSRHRAKHQTNPRSRPRSKQEAYVDSW--SGSED----------------EASNPFSFWV 296
             S    + +    SRP +++   + SW  +G ED                E       W 
Sbjct: 760  ISEATDREE----SRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWF 815

Query: 297  GENTNNLFR---------PRVREEANIRSKLRTNREDC--------FESE---SEDEFYK 336
            G     + R         P+  EE  I        E          FES+    E+E   
Sbjct: 816  GAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITV 875

Query: 337  QSWVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEV 385
             SW  P EEA+ +   +  E+  +  +   +      D   V +E        P  +EE+
Sbjct: 876  GSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEM 935

Query: 386  IIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKP 441
            I+ SWFW+  +A  E G  A CES+P  EEGAI GS + AE+    ++  G+        
Sbjct: 936  IVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLA 995

Query: 442  ESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKP 500
            + E+EAI GSWFW  DEA F+ NP PV++   R   + E E + S RPQ+W+EVTV+FKP
Sbjct: 996  D-EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKP 1054

Query: 501  GLFHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQ 556
            G +  VGF S SPF  P+EA+    EM   KP+N+ LSPEGE+QESLLQPDQPSPEF FQ
Sbjct: 1055 GPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQ 1114

Query: 557  YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            YDPSYRSV+EIREHLRA+ES E ES SC+CIQCELKIGSEEFEE LLLM+KIRDPFIHEI
Sbjct: 1115 YDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEI 1174

Query: 617  SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIE 676
            SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMI MAPPYPNLN+I+
Sbjct: 1175 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQ 1234

Query: 677  TFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKF 736
            T+IC+VCEETLA+SVDS EQL+GIRM+RHLT T DYHTL+ANYMSGFLSLL T NA+T+F
Sbjct: 1235 TYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRF 1294

Query: 737  HVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKM 796
            HVLKMLLNLSEN  + K+L SA+A+S F+GLFN EETNDNIQIV+ +F+NI N IK  + 
Sbjct: 1295 HVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ET 1353

Query: 797  SLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838
               DDDF++EPLISAF + E+ AK+LQ + DNQNDPE  Q++
Sbjct: 1354 VFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN 1395



 Score =  319 bits (818), Expect = 6e-87
 Identities = 210/513 (40%), Positives = 273/513 (53%), Gaps = 94/513 (18%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           MTGAEIE  AQ KPEKK GEEV+ G E ENDVPLVVRPKVRTQA                
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA---------------- 44

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                             Q+M GARPK +++ + GA  K +  AVGGAR K+ AKAIP +
Sbjct: 45  ------------------QIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVS 86

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
           R K+EAQ WAQ  FG E +S+ E  SQTN +A PL + +S  V K+K LS DRELVN D 
Sbjct: 87  RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT 146

Query: 181 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT 238
           E+FP  +   Q G QP F   EETNMGSWC  RP +++EAS  S F   D+ S +S FW+
Sbjct: 147 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS 205

Query: 239 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV 296
           G+E + +  P  R + + RS H A  + N  SR ++ QE Y+ S SGSEDE+     FW 
Sbjct: 206 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA 265

Query: 297 GENTNNLFRPRVREEANIRSKLRTNREDCFESE--SEDEFYKQSW------------VLP 342
            + TN    P  RE+ N RS+ R+ +E   ES   SE E + +SW            +  
Sbjct: 266 RDKTNTWSGP--REDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323

Query: 343 GEEANSRFRHRDK------------------------EDPNT-------------ALKLR 365
           G+EAN+R RHR K                        E+ NT             A+   
Sbjct: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383

Query: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWA 425
             K     R KQE R EEE +IG+WFWA  E+S+   AS   ES    E+ +I GS +W 
Sbjct: 384 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEAS--IESSLQVEDESIIGSWFWT 441

Query: 426 EEKSSLGAVAREEAKPESEEEAIFGSWFWDRDE 458
           EE++S+G  A  +++P ++ E I  S F  R++
Sbjct: 442 EEEASMGTGASSKSRPRTDGERIGDSLFGAREK 474


>gi|103472136 G protein-coupled receptor associated sorting protein 1
            [Homo sapiens]
          Length = 1395

 Score =  631 bits (1627), Expect = 0.0
 Identities = 367/702 (52%), Positives = 452/702 (64%), Gaps = 69/702 (9%)

Query: 200  EETNMGSWCYSRPRAREEASNESGFWSADE-----TSTASSFWTGEETSVRSWPREESNT 254
            EE  + SW +SR   + EA   S  W+ +E     T   +   T EET + SW  +E   
Sbjct: 700  EEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEA 759

Query: 255  RSRHRAKHQTNPRSRPRSKQEAYVDSW--SGSED----------------EASNPFSFWV 296
             S    + +    SRP +++   + SW  +G ED                E       W 
Sbjct: 760  ISEATDREE----SRPEAEEGDIIGSWFWAGEEDRLEPAAETREEDRLAAEKEGIVGSWF 815

Query: 297  GENTNNLFR---------PRVREEANIRSKLRTNREDC--------FESE---SEDEFYK 336
            G     + R         P+  EE  I        E          FES+    E+E   
Sbjct: 816  GAREETIRREAGSCSKSSPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITV 875

Query: 337  QSWVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEV 385
             SW  P EEA+ +   +  E+  +  +   +      D   V +E        P  +EE+
Sbjct: 876  GSWFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEM 935

Query: 386  IIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKP 441
            I+ SWFW+  +A  E G  A CES+P  EEGAI GS + AE+    ++  G+        
Sbjct: 936  IVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLA 995

Query: 442  ESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKP 500
            + E+EAI GSWFW  DEA F+ NP PV++   R   + E E + S RPQ+W+EVTV+FKP
Sbjct: 996  D-EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKP 1054

Query: 501  GLFHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQ 556
            G +  VGF S SPF  P+EA+    EM   KP+N+ LSPEGE+QESLLQPDQPSPEF FQ
Sbjct: 1055 GPWGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQ 1114

Query: 557  YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            YDPSYRSV+EIREHLRA+ES E ES SC+CIQCELKIGSEEFEE LLLM+KIRDPFIHEI
Sbjct: 1115 YDPSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEI 1174

Query: 617  SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIE 676
            SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMI MAPPYPNLN+I+
Sbjct: 1175 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQ 1234

Query: 677  TFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKF 736
            T+IC+VCEETLA+SVDS EQL+GIRM+RHLT T DYHTL+ANYMSGFLSLL T NA+T+F
Sbjct: 1235 TYICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRF 1294

Query: 737  HVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKM 796
            HVLKMLLNLSEN  + K+L SA+A+S F+GLFN EETNDNIQIV+ +F+NI N IK  + 
Sbjct: 1295 HVLKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ET 1353

Query: 797  SLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS 838
               DDDF++EPLISAF + E+ AK+LQ + DNQNDPE  Q++
Sbjct: 1354 VFSDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN 1395



 Score =  319 bits (818), Expect = 6e-87
 Identities = 210/513 (40%), Positives = 273/513 (53%), Gaps = 94/513 (18%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           MTGAEIE  AQ KPEKK GEEV+ G E ENDVPLVVRPKVRTQA                
Sbjct: 1   MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA---------------- 44

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                             Q+M GARPK +++ + GA  K +  AVGGAR K+ AKAIP +
Sbjct: 45  ------------------QIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVS 86

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
           R K+EAQ WAQ  FG E +S+ E  SQTN +A PL + +S  V K+K LS DRELVN D 
Sbjct: 87  RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT 146

Query: 181 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT 238
           E+FP  +   Q G QP F   EETNMGSWC  RP +++EAS  S F   D+ S +S FW+
Sbjct: 147 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS 205

Query: 239 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV 296
           G+E + +  P  R + + RS H A  + N  SR ++ QE Y+ S SGSEDE+     FW 
Sbjct: 206 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA 265

Query: 297 GENTNNLFRPRVREEANIRSKLRTNREDCFESE--SEDEFYKQSW------------VLP 342
            + TN    P  RE+ N RS+ R+ +E   ES   SE E + +SW            +  
Sbjct: 266 RDKTNTWSGP--REDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA 323

Query: 343 GEEANSRFRHRDK------------------------EDPNT-------------ALKLR 365
           G+EAN+R RHR K                        E+ NT             A+   
Sbjct: 324 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE 383

Query: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWA 425
             K     R KQE R EEE +IG+WFWA  E+S+   AS   ES    E+ +I GS +W 
Sbjct: 384 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEAS--IESSLQVEDESIIGSWFWT 441

Query: 426 EEKSSLGAVAREEAKPESEEEAIFGSWFWDRDE 458
           EE++S+G  A  +++P ++ E I  S F  R++
Sbjct: 442 EEEASMGTGASSKSRPRTDGERIGDSLFGAREK 474


>gi|216547715 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547682 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547672 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547663 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547655 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547646 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|216547639 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|39930463 basic helix-loop-helix domain containing, class B, 9
           [Homo sapiens]
          Length = 547

 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/448 (32%), Positives = 242/448 (54%), Gaps = 23/448 (5%)

Query: 383 EEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPE 442
           EE  I SWFW  +EA   G + +    +P      IG      E + + GA  +  +  E
Sbjct: 115 EEATINSWFWNGEEA---GNSFSTKNDKP-----EIGAQVCAEELEPAAGADCKPRSGAE 166

Query: 443 SEEEA-IFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV-EFKP 500
            EEE  + G+WFW+ D+  FD NP PV ++         E+N  +RP+ W EVT+    P
Sbjct: 167 EEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKP--QPVYEINEKNRPKDWSEVTIWPNAP 224

Query: 501 GLFHGV-GFRSTSPFGIPEEASEMLEAKPKN---LELSPEGEEQESLLQPDQPSPEFTFQ 556
            +   V GFRS +P      +  +L +  +N   L ++       +     QP PE  F 
Sbjct: 225 AVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFD 284

Query: 557 YDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEI 616
            DP  +++ EIR  +R RE    + ++C C + E  + SEEFE+ + L+    DP IH+I
Sbjct: 285 SDPCIQTIDEIRRQIRIREVNGIKPFACPC-KMECYMDSEEFEKLVSLLKSTTDPLIHKI 343

Query: 617 SKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNM-- 674
           ++IAMG+ +   F ++FI + GVV+LIE+LL++PS  +R    + +I + PP  +     
Sbjct: 344 ARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRK---KTVITLNPPSGDERQRK 400

Query: 675 IETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANART 734
           IE  +  +C+ET++  ++S  Q +G+++L  LT    +H ++ANY S    LL++ N +T
Sbjct: 401 IELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKT 460

Query: 735 KFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSG 794
           +  VLK+LLN+SENP  A+ + + KAL+    +FN +E   N+   + +F NI   I+ G
Sbjct: 461 RNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKG 520

Query: 795 KMSLIDDDFSLEPLISAFREFEELAKQL 822
            + ++ D  S   L++ FRE +E+ + +
Sbjct: 521 SIVVV-DHLSYNTLMAIFREVKEIIETM 547



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/240 (22%), Positives = 91/240 (37%), Gaps = 50/240 (20%)

Query: 81  MGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFG--TEA 138
           M G + KT AQ       KT+ +A   A++  + +A    RP  + +A A+++ G  T+A
Sbjct: 1   MAGTKNKTRAQA------KTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDA 54

Query: 139 VSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGP 198
           V++ + VS+   VA           TK   LS  + L     +  P              
Sbjct: 55  VAEMKAVSKNKVVA----------ETKEGALSEPKTLGKAMGDFTPKA------------ 92

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
           G E+   +        + EA  ++ FW+ +E +  S FW GEE       + +       
Sbjct: 93  GNESTSST-------CKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQ 145

Query: 259 RAKHQTNPRS----RPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEANI 314
               +  P +    +PRS  E         E+E  N    W  E  +  F P  +  + I
Sbjct: 146 VCAEELEPAAGADCKPRSGAE---------EEEEENVIGNWFWEGDDTSFDPNPKPVSRI 196



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 65/279 (23%), Positives = 106/279 (37%), Gaps = 61/279 (21%)

Query: 1   MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
           M G + +  AQAK EKKA  +  AG ERE     VVRP  +T+A   A+  ++T +V   
Sbjct: 1   MAGTKNKTRAQAKTEKKAAIQAKAGAERE--ATGVVRPVAKTRAKAKAKTGSKTDAV--- 55

Query: 61  RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA 120
                A+  + ++ K   +   GA           + PKT  +A+G    K         
Sbjct: 56  -----AEMKAVSKNKVVAETKEGAL----------SEPKTLGKAMGDFTPKAG------- 93

Query: 121 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA 180
              +   +  ++E GT+A   A   +  N+  W    A +   TK+    +  ++   + 
Sbjct: 94  --NESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEEL 151

Query: 181 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRA-REEASNESGFWSADETSTASSFWTG 239
           E   G                      C  R  A  EE  N  G W          FW G
Sbjct: 152 EPAAGAD--------------------CKPRSGAEEEEEENVIGNW----------FWEG 181

Query: 240 EETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYV 278
           ++TS    P+  S    + +  ++ N ++RP+   E  +
Sbjct: 182 DDTSFDPNPKPVSRI-VKPQPVYEINEKNRPKDWSEVTI 219



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 9/97 (9%)

Query: 338 SWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRF-----EEEVIIGSWFW 392
           SW   GEEA + F  ++ + P    ++ A++   +     +PR      EEE +IG+WFW
Sbjct: 121 SWFWNGEEAGNSFSTKN-DKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW 179

Query: 393 AEKEASLEGG---ASAICESEPGTEEGAIGGSAYWAE 426
              + S +      S I + +P  E         W+E
Sbjct: 180 EGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSE 216


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score =  218 bits (555), Expect = 2e-56
 Identities = 223/835 (26%), Positives = 357/835 (42%), Gaps = 107/835 (12%)

Query: 42   TQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMG----GARPKTEAQGITGAR 97
            +Q   G+      + V  +RP    Q+ +G+      QV G    GA    +A G +  +
Sbjct: 1608 SQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCS--K 1665

Query: 98   PKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLAT 157
            P  + +A+GG           G  P    Q    S  G+E  S   G S   A    L  
Sbjct: 1666 PGFEDQAIGG-----------GFWPGAGDQTGGGSRPGSEDQSSGIG-SWGVAGGQVLGG 1713

Query: 158  AESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREE 217
            A  G   +S G S            + GT  Q   + W GPG++    +   S+P   ++
Sbjct: 1714 ARPGPADQSSGGS------------WAGTGNQSSGRSWIGPGDQ----AVDCSKPEFEDQ 1757

Query: 218  ASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAY 277
            A    G W+   +  +   W G                   R  ++    SR  S+ +A 
Sbjct: 1758 ACG-GGSWAGAGSQASGESWAGS------------------RPGNEAIGGSRMGSEDQAT 1798

Query: 278  VDSWSGSEDEASNPF--SFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFY 335
              SW+ SED+AS  F  SF V  N    F P    EA I S   T  +    S  +D+  
Sbjct: 1799 GGSWARSEDQASGRFQVSFEVEANEGFWFGPGA--EAVIGSWCWTEEKADIVSRPDDK-- 1854

Query: 336  KQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEK 395
                    +EA +  R R  E+     ++ A+    S       R EE   +GS   AE 
Sbjct: 1855 --------DEATTASRSRAGEEAMICSRIEAENKASSG---SWIRSEEVAYMGSCVGAEA 1903

Query: 396  EASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGA--------VAREEAKPESEEEA 447
             A  E GA A   +  G E GA  G+   A   +  GA            E++  + EEA
Sbjct: 1904 GAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEA 1963

Query: 448  IFGSWFWDR----DEACFDLNPCPVYKVSDRFRDAAEELNASS-RPQTWDEVTVEFKPGL 502
               SW   R    DE   + +P  + ++S R    AE  N+++ R ++  + + E   G 
Sbjct: 1964 GVESWTLARNVGEDELSRESSP-DIEEISLRSLFWAESENSNTFRSKSGKDASFESGAGD 2022

Query: 503  FHGVGFRSTSPFGIP---------EEASEMLEAKPKNLELSPEGEEQESLLQPDQ----- 548
               +  +  +  G+          E  SE   A     + S E       + P       
Sbjct: 2023 NTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGAGMGSW 2082

Query: 549  ------PSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFL 602
                     +F  Q + S+    E R+  R  E  ++  WSC C + E  +   + E+ +
Sbjct: 2083 DGAMIWSETKFAHQSEASFPVEDESRKQTRTGE--KTRPWSCRC-KHEANMDPRDLEKLI 2139

Query: 603  LLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENM 662
             +++   DP +HEI+  A+   +   ++ + +R+ G +S+IE+LLN P   VR   L  +
Sbjct: 2140 CMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNAL 2199

Query: 663  IHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSG 722
             +++    N   ++T++ QVCE+T+ + ++S  QL G+R++RHLT+T +Y  ++ NY+S 
Sbjct: 2200 NNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVTNYISE 2259

Query: 723  FLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIK 782
            FL LLT  +  TK HVL MLLN S+NP++ K L  A A +  + +F+ +ET +NI   + 
Sbjct: 2260 FLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKETKENILNALS 2319

Query: 783  MFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQ 837
            +F+NI+   K    +   D FS   L   F+  +  AK+L+A     NDPEV ++
Sbjct: 2320 LFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDPEVKER 2374



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 128/516 (24%), Positives = 189/516 (36%), Gaps = 133/516 (25%)

Query: 43   QATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK--- 99
            QA+ G+    E +S   +   T  QA  G+R     Q  GGA   T  Q   G++P+   
Sbjct: 1427 QASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFEN 1486

Query: 100  --TDARAVGGARSKTDAKAIPGARPKDEAQAWAQS------EFGTEAVSQAEGVSQTNAV 151
              T+  +  GA  +    +  G   +   ++WA S       F    V QA G S T A 
Sbjct: 1487 QTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGA- 1545

Query: 152  AWPLATAE----SGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFG---------- 197
              P +          V+     +  RE V  D+    G + Q     W G          
Sbjct: 1546 GHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRL--GLRDQSSGDSWAGTGDQASGWFC 1603

Query: 198  --PGEETNMGSW--------CYSRPRAREEASNESGFWSADETSTASSFWTG----EETS 243
              PG +TN GSW          SRP    ++S  +G W +  +  + S WTG    ++  
Sbjct: 1604 VCPGSQTNGGSWGGASGQDVGGSRPGPTNQSS--AGSWDSPGSQVSGSCWTGAGAVDQAG 1661

Query: 244  VRSWPREESNTRSR---HRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV-GEN 299
              S P  E           A  QT   SRP            GSED++S   S+ V G  
Sbjct: 1662 GCSKPGFEDQAIGGGFWPGAGDQTGGGSRP------------GSEDQSSGIGSWGVAGGQ 1709

Query: 300  TNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPN 359
                 RP   ++++  S   T  +             +SW+ PG++A             
Sbjct: 1710 VLGGARPGPADQSSGGSWAGTGNQSS----------GRSWIGPGDQA------------- 1746

Query: 360  TALKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAI 418
                      VD  +    P FE++    GSW  A  +AS E  A     S PG E  AI
Sbjct: 1747 ----------VDCSK----PEFEDQACGGGSWAGAGSQASGESWAG----SRPGNE--AI 1786

Query: 419  GGSAYWAEEKSSLGAVAREEAKP----------ESEE--------EAIFGSWFWDRDEAC 460
            GGS   +E++++ G+ AR E +           E+ E        EA+ GSW W  ++A 
Sbjct: 1787 GGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKAD 1846

Query: 461  FDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV 496
                P           D  +E   +SR +  +E  +
Sbjct: 1847 IVSRP-----------DDKDEATTASRSRAGEEAMI 1871



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 118/541 (21%), Positives = 198/541 (36%), Gaps = 102/541 (18%)

Query: 1    MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
            +  ++ E    A+ + K    V++      D     +P+V   +     P    K    +
Sbjct: 965  LASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNS 1024

Query: 61   RPKTEAQAMSGARPKTEVQVMGGAR------PKTEAQGITGARPKTDARA--VGGAR--- 109
               ++A+A +G     +VQV+   +       K + +G + A PK +A A  VG A+   
Sbjct: 1025 NAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQA 1084

Query: 110  -SKTDAKAIPGARPKDEAQAWAQSEFGTEA----VSQAEGVSQTNAVAWPLATAESGSVT 164
             + + ++ + GAR K +    A  + GT A     +Q + V+ +     P A  +S S +
Sbjct: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144

Query: 165  KSKGLSMDRELVNVDAETFP--------GTQGQKGIQP------WFGPGEETNMGS--WC 208
            +++  + D      +AE  P        GTQ  +  QP      W G G E  + +  W 
Sbjct: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204

Query: 209  YSRPRAREEASNESGFWSADETSTASSFWTG---------------EETSVRSWPREESN 253
              R +  +     S  W+ DE   +   W+G               +ETSV+SW      
Sbjct: 1205 KFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSW------ 1258

Query: 254  TRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEAN 313
              +  RA++     +  R+ ++A    W+G +         W G+  +         +A+
Sbjct: 1259 --AGARAENVVGIGTWARAGEQASGGLWAGGQTSEGT----WAGDKASGGAWTGAENQAS 1312

Query: 314  IRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSD 373
              S      +   E  +  +    SW  PG +A+                          
Sbjct: 1313 GGSWALAGNQAIGELWAAGQASDGSW--PGGQASG------------------------- 1345

Query: 374  RVKQEPRFEEEVIIGSWFWAEKEASLEG---GASAICESEPGTEEGAI--GGSAYWAEEK 428
                     EE I GSW  AE +AS EG   GA A   S      G +   G   WA   
Sbjct: 1346 ----VSWVGEEAIGGSWTGAENQAS-EGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTS 1400

Query: 429  SSLGAVAREEAKPESEEEAI-FGSWFWDRDEACFDLNPCPVYKVSDR-FRDAAEELNASS 486
               G      +KP  E++A   GSW     +A       P  + S R + D A++ +  S
Sbjct: 1401 DQSGG----GSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGS 1456

Query: 487  R 487
            R
Sbjct: 1457 R 1457



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 120/551 (21%), Positives = 206/551 (37%), Gaps = 110/551 (19%)

Query: 3    GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATT--GARPKTETKSVPAA 60
            GA+   SAQ +    +  E + G   +     +  PK  T A T   A+P+    S    
Sbjct: 1073 GADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGET 1132

Query: 61   RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIP-- 118
             P    ++MS +  +   +    A+P+ EA       P +++   GG+ ++   K  P  
Sbjct: 1133 LPGARDKSMSTSEAEATAEDEAYAKPEAEAM------PTSESE--GGSGTQACRKTQPNI 1184

Query: 119  --------GARPKDEAQAWAQSEFGT------EAVSQAEGVSQTNAVAWPLATAESGSVT 164
                    G      A+ W +  F T       +VS A+  ++ +  +W  A+ ++G + 
Sbjct: 1185 HDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAG-II 1243

Query: 165  KSKGLSMDRELVNVDAETFPGTQGQK--GIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
            +S  ++ D   V    +++ G + +   GI  W   GE+ + G W   +           
Sbjct: 1244 RSWAVACDETSV----KSWAGARAENVVGIGTWARAGEQASGGLWAGGQ--------TSE 1291

Query: 223  GFWSADETSTASSFWTGEETSVR--SWPREESNTRSRHRAKHQTNPRSRPRSK------- 273
            G W+ D+ S  +  WTG E      SW    +       A  Q +  S P  +       
Sbjct: 1292 GTWAGDKASGGA--WTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV 1349

Query: 274  -QEAYVDSWSGSEDEAS------------NPFSFWVG--------------ENTNNLFRP 306
             +EA   SW+G+E++AS            +  S+W G              + +    +P
Sbjct: 1350 GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKP 1409

Query: 307  RVREEANIRSKLRTNREDCFESE---SEDEFYKQSWVLPGEEAN--SRFRHRDKEDPNTA 361
            R  ++A+                    ED+   +SW    ++A+  SR  H D+      
Sbjct: 1410 RFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGA- 1468

Query: 362  LKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420
                    +D      +PRFE +    GSW  A  +A   GG S +     G E+ + G 
Sbjct: 1469 ----WAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQA---GGGSKV-----GPEDQSSGR 1516

Query: 421  SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVY--KVSDR--FR 476
            S  WA     +             ++A  GSW      A   + P P++  +VS R  + 
Sbjct: 1517 S--WANSGDQISG----GFLVGIVDQANGGSWTGAGHPA--SVGPKPIFEDQVSGRGSWA 1568

Query: 477  DAAEELNASSR 487
            DA E++   SR
Sbjct: 1569 DAREQVVGDSR 1579



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 88/386 (22%), Positives = 141/386 (36%), Gaps = 60/386 (15%)

Query: 79   QVMGGARPKTEAQGITGARPKTDARAVG-----GARSKTDAKAIPGARPKDEAQAWAQSE 133
            Q  GG+   T  Q   G++P+ + +A G     GA  +    ++ G   +   ++WA + 
Sbjct: 1390 QAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTA 1449

Query: 134  FGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDR-ELVNVDAETFPGTQGQKGI 192
                  S+   V Q++  AW      +G++ +S G S  R E    +  ++ G  GQ G 
Sbjct: 1450 DQASGGSRLGHVDQSSGGAW------AGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGG 1503

Query: 193  QPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTG--EETSVRSWPRE 250
                GP ++++  SW  S  +         GF            WTG     SV   P  
Sbjct: 1504 GSKVGPEDQSSGRSWANSGDQI------SGGFLVGIVDQANGGSWTGAGHPASVGPKPIF 1557

Query: 251  ESNTRSRHR---AKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTN-NLFRP 306
            E     R     A+ Q    SR   + ++  DSW+G+ D+AS  F    G  TN   +  
Sbjct: 1558 EDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGG 1617

Query: 307  RVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRA 366
               ++        TN+               SW  PG + +                   
Sbjct: 1618 ASGQDVGGSRPGPTNQSSA-----------GSWDSPGSQVSGSC-------------WTG 1653

Query: 367  QKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAE 426
               VD      +P FE++  IG  FW        GG      S PG+E+ + G  ++   
Sbjct: 1654 AGAVDQAGGCSKPGFEDQA-IGGGFWPGAGDQTGGG------SRPGSEDQSSGIGSWGVA 1706

Query: 427  EKSSLGAVAREEAKPESEEEAIFGSW 452
                LG      A+P   +++  GSW
Sbjct: 1707 GGQVLGG-----ARPGPADQSSGGSW 1727



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 107/470 (22%), Positives = 185/470 (39%), Gaps = 62/470 (13%)

Query: 3    GAEIEPSAQAKPEKKAGEEVIAGPERENDV---PLVVRPKVRTQATTGARP-----KTET 54
            GA ++    A+P+  A  +    P  +N V   P VV      + T G+        ++ 
Sbjct: 911  GAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQR 970

Query: 55   KSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDA 114
            +++P AR K +  +   ++       MG A+P+  A       P    +  G + + + A
Sbjct: 971  ETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKA 1030

Query: 115  KAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRE 174
            +A  GA      Q    + F  E +  A+   + N+ A P A A + +V    G +  + 
Sbjct: 1031 EA--GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV----GSAQPQA 1084

Query: 175  LVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADET-STA 233
            + N  +ET  G + +        P   T  G+   ++P+    +  E+   + D++ ST+
Sbjct: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144

Query: 234  SSFWTGEETS-----VRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
             +  T E+ +       + P  ES   S  +A  +T P           V+ W  +E   
Sbjct: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204

Query: 289  SNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANS 348
               F    G+  N++       EA+I S         +   S+     +SW +  +E   
Sbjct: 1205 KFRFQTMDGDWENSVSWADDENEASIGS---------WSGASDKAGIIRSWAVACDE--- 1252

Query: 349  RFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICE 408
                       T++K  A             R E  V IG+W  A ++AS  GG  A  +
Sbjct: 1253 -----------TSVKSWA-----------GARAENVVGIGTWARAGEQAS--GGLWAGGQ 1288

Query: 409  SEPGTEEG--AIGGSAYWAEEKSSLG--AVAREEAKPE--SEEEAIFGSW 452
            +  GT  G  A GG+   AE ++S G  A+A  +A  E  +  +A  GSW
Sbjct: 1289 TSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSW 1338



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 65/265 (24%), Positives = 108/265 (40%), Gaps = 30/265 (11%)

Query: 29   ENDVPLVVRPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKT 88
            E    +V RP  + +ATT +R +   +++  +R + E +A SG+  ++E     G+    
Sbjct: 1842 EEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGA 1901

Query: 89   EAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQA--WAQSEFGTEAVSQAEGVS 146
            EA     A    +A A  GA +  +A A  GA P  E+ A  W+     T   S+     
Sbjct: 1902 EAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGE 1961

Query: 147  QTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGS 206
            +    +W LA    G    S+  S D E +++ +              ++   E +N   
Sbjct: 1962 EAGVESWTLA-RNVGEDELSRESSPDIEEISLRS-------------LFWAESENSNT-- 2005

Query: 207  WCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSW----PREESNTRSRHRAKH 262
                R ++ ++AS ESG  + D TS    F       + SW        S  +S  +AK 
Sbjct: 2006 ---FRSKSGKDASFESG--AGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKA 2060

Query: 263  QTNPRSR---PRSKQEAYVDSWSGS 284
            + +  SR   P     A + SW G+
Sbjct: 2061 KKSSESRGIYPYMVPGAGMGSWDGA 2085



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 77/270 (28%), Positives = 120/270 (44%), Gaps = 41/270 (15%)

Query: 40  VRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK 99
           VRT A  G+  K ET        +++  A++ A  KT+ QV  GA  +T A+   GA  +
Sbjct: 127 VRTLARNGSTVKMET----VVGVQSQTLAINEAEIKTKPQVEIGA--ETGARSGPGAEVE 180

Query: 100 TDARAVGGARSKTDAKAIPGARPK--DEAQAWAQSEFGTEAVS------------QAEGV 145
           T A A+   R+ + AKA+ GA P+   E++  A +   TEAV+              E V
Sbjct: 181 TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV 240

Query: 146 SQTNAVAWPLATAESGSVTKSKGLSM------DRE-LVNVDAETFPGTQGQKGIQPWFGP 198
           +QT+A A  +   E+ + TK+K  ++       RE +    AET    + +  I      
Sbjct: 241 TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT 300

Query: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
             ET        R  A+  A+N++G    DET T +     EET   S  + +S  R   
Sbjct: 301 QSET----LAVPREVAKMGATNKTGI--VDETKTRAL----EETV--SVAKTQSEARPGA 348

Query: 259 RAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
               + NP     S++ A VD  S ++ +A
Sbjct: 349 TVDARGNPNG--MSREVAGVDMKSCAQSQA 376



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 54/235 (22%), Positives = 95/235 (40%), Gaps = 15/235 (6%)

Query: 3   GAEIEPSAQA----KPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVP 58
           GAE+E  A A    +   +A   V A PE +++  +V    V T+A T    K + + V 
Sbjct: 176 GAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVA 235

Query: 59  AARPKTEAQAMSGARPKTEVQVMGGAR-----PKTEAQGITGARPKTDARAVGGARSKTD 113
                T+  A +G   K E      A+      KTEA+     + K +   +    ++ +
Sbjct: 236 MKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEIN 295

Query: 114 AKAIPG----ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKG- 168
              +      A P++ A+  A ++ G    ++   + +T +VA   + A  G+   ++G 
Sbjct: 296 RVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGN 355

Query: 169 -LSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
              M RE+  VD ++   +Q    IQ    PG        C +  RA   A   +
Sbjct: 356 PNGMSREVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRA 410



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 111/552 (20%), Positives = 192/552 (34%), Gaps = 106/552 (19%)

Query: 3    GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAARP 62
            GA  + +   +P+  A  +    P  +N        K+R   TT         +  +ARP
Sbjct: 791  GAGTDTTGSVQPQIVANSQGEVLPGAKN--------KIRGNPTTVPNSGVGPYTTDSARP 842

Query: 63   KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
            +  A +     P  + +V       ++A+   GA      +AV  +  +T    +PGA+ 
Sbjct: 843  QAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCET----LPGAKN 898

Query: 123  KDEAQAWAQSEFG----TEAVSQAEGVSQTNAVAWPLA----------TAESGSVTKSKG 168
            K      A S+ G    T   +Q + V+ +     P A           +++G+   + G
Sbjct: 899  KVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVG 958

Query: 169  LSMDRELVNVDAETFPG----TQGQKGIQPWFGPGEETNMG---------SWCYSRPRAR 215
             +  + L +   ET PG     +G   +    G  E+T MG         S   + P AR
Sbjct: 959  STQPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDT-MGSAQPQVVANSQRETLPGAR 1017

Query: 216  EEASNES----------GFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTN 265
             +    S          G   + +    +SF        ++  R  SN   +  A   T 
Sbjct: 1018 NKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV 1077

Query: 266  PRSRPRSKQEAYVDSWSGSEDEASNPF----SFWVGENTNNLFRPRV------REEANIR 315
              ++P++   +  ++  G+ ++             G  T +  +P++            R
Sbjct: 1078 GSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGAR 1137

Query: 316  SKLRTNREDCFESESEDEFY--KQSWVLPGEEA--NSRFRHRDKEDPNTA---------- 361
             K  +  E   E+ +EDE Y   ++  +P  E+   S  +   K  PN            
Sbjct: 1138 DKSMSTSE--AEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVE 1195

Query: 362  --------LKLRAQ-KDVDSDRVKQEPRFEEEVIIGSWFWAE-------------KEASL 399
                    +K R Q  D D +        E E  IGSW  A               E S+
Sbjct: 1196 DWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSV 1255

Query: 400  EGGASAICESEPG----TEEGAIGGSAYWAEEKSSLGAVAREEAK----PESEEEAIFGS 451
            +  A A  E+  G       G       WA  ++S G  A ++A       +E +A  GS
Sbjct: 1256 KSWAGARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGS 1315

Query: 452  WFWDRDEACFDL 463
            W    ++A  +L
Sbjct: 1316 WALAGNQAIGEL 1327



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 85/413 (20%), Positives = 154/413 (37%), Gaps = 49/413 (11%)

Query: 63  KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
           KT ++A SGA  +   Q    A+ +TEA  I GA  K DA     A  K  A A   A  
Sbjct: 397 KTMSRAESGADTRASAQPQIFAKTQTEA--IPGA--KIDAGGNTNAMCKVGAGADVRACI 452

Query: 123 KDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAET 182
           + +  A  Q+E  + A  + +G   TN ++  +  A+  +  + + ++        DA+ 
Sbjct: 453 QPQTVAKKQAEVTSGA--RVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKV 510

Query: 183 FPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFW----------------- 225
               +G        G        S   + P AR+++                        
Sbjct: 511 --KNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLSCTQPQL 568

Query: 226 -SADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQT------NPRSRPRSKQEAYV 278
            ++ +  T S        +V + P+E +    + +   Q+      N R + R K +A  
Sbjct: 569 VASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKC 628

Query: 279 DSWSGSEDEASNPFSFWVGENTNNLFRPRV--REEANIRSKLRTNREDCFESESEDEFYK 336
            +  G + +        V      L   RV  R   N  SK  T  +     +       
Sbjct: 629 KTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVCGQPLVVANP 688

Query: 337 QSWVLPGEEANSRFRHRDKEDPNTALKLRA-QKDVDSDRVKQEPRFEEEVIIGSWFWAEK 395
           Q   LPG       +++ K +P+T LK+ A +   DS + +    F+ E ++G+      
Sbjct: 689 QGEALPGA------KNKVKGNPHTVLKVGAGEGTTDSAQPEAVVSFQGEALLGT------ 736

Query: 396 EASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAI 448
           +  ++G  + + ++E G  EGA+G +       S   A+   + K +    A+
Sbjct: 737 KNKVKGNPNVVLKAEVG--EGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAV 787



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 55/224 (24%), Positives = 88/224 (39%), Gaps = 44/224 (19%)

Query: 2   TGAEIEPSAQAKPEKKAGEEVIAGPEREN--------------DVPLVVRP----KVRTQ 43
           +GA+   SAQ +   K   E I G + +               DV   ++P    K + +
Sbjct: 404 SGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAE 463

Query: 44  ATTGARPKTETKSVPAARPKTEAQAMSGARPK----TEVQVMGGARPKTEAQGITGARPK 99
            T+GAR      +   ++  T A   + A+P+    T  + M  A+ K   +G   A  K
Sbjct: 464 VTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKVKN--RGNPNAMTK 521

Query: 100 TDARAVGGARSKTDAKAIPGARPKDEA--QAWAQSEFGTEAVSQAEGVSQTNAVAWPLAT 157
             A+A    R+ +  +A+P AR K        A+   GT+ +S     +Q   VA   A 
Sbjct: 522 AGAKA--NLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLS----CTQPQLVASVQAD 575

Query: 158 AESGSVTKSKG--LSMDRELVNVD----------AETFPGTQGQ 189
             S    K +G   +M +E   VD           E  P T+G+
Sbjct: 576 TLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGK 619


>gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]
          Length = 558

 Score =  172 bits (437), Expect = 9e-43
 Identities = 123/426 (28%), Positives = 212/426 (49%), Gaps = 36/426 (8%)

Query: 420 GSAYWAEEKSSLGAVAREEAKPE------SEEEAIFGSWFWDRDEACFDLNPCPVYKVSD 473
           GS     E++S+G  + +E +        + EE   GSWFW  +E         VYK   
Sbjct: 147 GSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ-----VYKPLP 201

Query: 474 RFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLEL 533
           + ++         +P+   + T+  K  +      R+     +P E  E          L
Sbjct: 202 KIQE---------KPKPTHKPTLTIKQKVI--AWSRARYIVLVPVEGGEQ--------SL 242

Query: 534 SPEGEEQ--ESLLQPD---QPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQ 588
            PEG     E+L++     +P  +    + P Y+++ EI++ +R RE       +C C  
Sbjct: 243 PPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKS 302

Query: 589 CELKIGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLN 648
               +  +EF++ + L+   +DPFIHEI+ + MG+  A  FT+D I D G+  +IE L+N
Sbjct: 303 RGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVN 362

Query: 649 YPSSRVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTM 708
            P+ +     L  +   +         E++I QVC+  ++  ++S  QL G+++L HL++
Sbjct: 363 NPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSI 422

Query: 709 TIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLF 768
             + H +I +Y+  FL+LL   + +TKF+VLK+   LS+N A  ++L SAK LS  V  F
Sbjct: 423 KFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPF 482

Query: 769 NIEETNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDN 828
           N  E+  NI  +I++F+NI+   K+       + F+   LIS F+E ++  ++LQ  +  
Sbjct: 483 NKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQ-DLAE 541

Query: 829 QNDPEV 834
            +DPEV
Sbjct: 542 HSDPEV 547



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 66/232 (28%), Positives = 96/232 (41%), Gaps = 25/232 (10%)

Query: 60  ARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPG 119
           AR K EA    G       +V G    KT+A+ +  A  KT+        S T AKA  G
Sbjct: 10  ARGKAEAGLQDGISGPATARVNG----KTQAEAVAEAELKTE--------SVTQAKAGDG 57

Query: 120 ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW----PLATAESGSVTKSKGLSMDREL 175
           A  +     + ++   T  V + E  ++T  +      PLA       TKSK + M R  
Sbjct: 58  AMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVS 117

Query: 176 VNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASS 235
               +E       +  I+ +    ++ N GS    RP  REE S        DE +  S 
Sbjct: 118 TVTKSEVKVVAVIEANIRSYAKSHDKANTGS----RPDRREETSIGMKSSDEDEENICSW 173

Query: 236 FWTGEETSVRS--WPREESNT---RSRHRAKHQTNPRSRPRSKQEAYVDSWS 282
           FWTGEE SV S  WP EE++    +   + + +  P  +P    +  V +WS
Sbjct: 174 FWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWS 225



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 30/205 (14%)

Query: 94  TGARPKTDARAVGGARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAW 153
           +G   +   +A  G +      A      K +A+A A++E  TE+V+QA+        A 
Sbjct: 4   SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAK--------AG 55

Query: 154 PLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPR 213
             A   + +VT  + +++ RE++ V+  T                  +T +     ++P 
Sbjct: 56  DGAMTRTHTVTYREAMAVTREVIKVEDTT------------------KTRVMVETKTKPL 97

Query: 214 AREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRSK 273
           A      ++      +    S   T  ++ V+     E+N RS  ++  + N  SRP  +
Sbjct: 98  AERSIVPQT----KSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRR 153

Query: 274 QEAYVDSWSGSEDEASNPFSFWVGE 298
           +E  +   S  EDE +    FW GE
Sbjct: 154 EETSIGMKSSDEDEENICSWFWTGE 178



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 306 PRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLR 365
           P+ + +A   S++ T  +   +  +  E   +S+    ++AN+  R   +E+ +  +K  
Sbjct: 104 PQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMK-- 161

Query: 366 AQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLE 400
              D D + +       EE  +GSWFW E+E SL+
Sbjct: 162 -SSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQ 195


>gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]
          Length = 453

 Score =  130 bits (326), Expect = 7e-30
 Identities = 69/239 (28%), Positives = 135/239 (56%), Gaps = 1/239 (0%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + + + ++ L ++++  DPFI E++ + +G  +A  F ++ IR+ G V +I  L+     
Sbjct: 202 LSAPDLQKVLNILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTKDP 261

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            +R      + +++    N   I+T+I QVC++T+   +DS  Q+ G+R+L ++T+T  Y
Sbjct: 262 IIREKTYNALNNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHY 321

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             L++     F +LL   N  TK  ++K+++N +ENPA+ ++L S K  S  + LFN E 
Sbjct: 322 QHLLSYSFPDFFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPSELISLFNKEW 381

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQND 831
             + +  ++ +F+NI++ IK+  ++    +FS   L   F+E     K+++A + N ND
Sbjct: 382 DREILLNILTLFENINDNIKNEGLASSRKEFSRSSLFFLFKESGVCVKKIKA-LANHND 439


>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  127 bits (318), Expect = 6e-29
 Identities = 71/230 (30%), Positives = 129/230 (56%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           +  +E ++ L L++    P+I E + IA+G  +A  F RD IRD G + ++  +LN    
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            V+   L  + +++    N   ++ ++ QVC++T+   ++S  QL G+R+L ++T+T +Y
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++AN +S F  L +  N  TK  VLK+LLNL+ENPA+ ++L  A+  S    LFN +E
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQL 822
             + I  ++ +F+NI++  K  +     + F    L    +EF+  A ++
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKV 347


>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  127 bits (318), Expect = 6e-29
 Identities = 71/230 (30%), Positives = 129/230 (56%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           +  +E ++ L L++    P+I E + IA+G  +A  F RD IRD G + ++  +LN    
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            V+   L  + +++    N   ++ ++ QVC++T+   ++S  QL G+R+L ++T+T +Y
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++AN +S F  L +  N  TK  VLK+LLNL+ENPA+ ++L  A+  S    LFN +E
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQL 822
             + I  ++ +F+NI++  K  +     + F    L    +EF+  A ++
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKV 347


>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score =  127 bits (318), Expect = 6e-29
 Identities = 71/230 (30%), Positives = 129/230 (56%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           +  +E ++ L L++    P+I E + IA+G  +A  F RD IRD G + ++  +LN    
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            V+   L  + +++    N   ++ ++ QVC++T+   ++S  QL G+R+L ++T+T +Y
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++AN +S F  L +  N  TK  VLK+LLNL+ENPA+ ++L  A+  S    LFN +E
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQL 822
             + I  ++ +F+NI++  K  +     + F    L    +EF+  A ++
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKV 347


>gi|238776793 SVH protein isoform b [Homo sapiens]
          Length = 308

 Score =  123 bits (309), Expect = 6e-28
 Identities = 71/250 (28%), Positives = 139/250 (55%), Gaps = 12/250 (4%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+ +L ++T+T D+
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK  VLK+LLNLSENPA+ + L  A+  S F+ L++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 237

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 238 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 291

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 292 H-HDAEVKEK 300


>gi|31377663 SVH protein isoform a [Homo sapiens]
          Length = 343

 Score =  123 bits (309), Expect = 6e-28
 Identities = 71/250 (28%), Positives = 139/250 (55%), Gaps = 12/250 (4%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 93  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 152

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+ +L ++T+T D+
Sbjct: 153 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 212

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK  VLK+LLNLSENPA+ + L  A+  S F+ L++   
Sbjct: 213 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 272

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 273 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 326

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 327 H-HDAEVKEK 335


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 49/201 (24%), Positives = 109/201 (54%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           +G  +  + L L+ K  DPFI +++ + +   +     ++ IR  G + +I  ++N    
Sbjct: 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDP 442

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  M +++  Y N   ++ ++ +V ++ +A +++S  Q+ G++ L ++T+T DY
Sbjct: 443 HIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDY 502

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             L+ N ++ F  LL+    + K  +LK+L N +ENP + KKL S +  + F  L+N   
Sbjct: 503 QHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYV 562

Query: 773 TNDNIQIVIKMFQNISNIIKS 793
            ++ +   + +F+ I + +++
Sbjct: 563 ESEILINALTLFEIIYDNLRA 583



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 62/283 (21%), Positives = 94/283 (33%), Gaps = 29/283 (10%)

Query: 2   TGAEIEPSAQAKPEKKAGEEVIAGPERENDV-----PLVVRPKVRTQATTGARPKTETKS 56
           + AE +  A ++ ++  G  V  GP+ E+ V       +  P   T+A   A       +
Sbjct: 103 SSAEAQSGAGSQAQEADGAGV--GPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGA 160

Query: 57  VPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKA 116
              A    EA+    A P   V     A P    +G   A P   A A G A     A+A
Sbjct: 161 PKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEA 220

Query: 117 IPGARPKDEAQAWAQSEF-------------GTEAVSQAEGVSQTNAVAWPLATAESGSV 163
              A P   A     +E              GT A  +A   + T A+  P AT+ +G+V
Sbjct: 221 PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAI--PKATSATGAV 278

Query: 164 TKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESG 223
            K  G  + R       +          +   F PG+         +   A      ++ 
Sbjct: 279 PKGGGKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDGA-------AAAAAASANGGQAF 331

Query: 224 FWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNP 266
                ++    S WT  E+   S P  +   R R     Q  P
Sbjct: 332 LAEVPDSEEGESGWTDTESDSDSEPETQRRGRGRRPVAMQKRP 374



 Score = 37.0 bits (84), Expect = 0.076
 Identities = 53/204 (25%), Positives = 73/204 (35%), Gaps = 25/204 (12%)

Query: 4   AEIEPSAQAKPEKKAGEEV-----IAGPERENDVPLVVRPKVRTQA-----TTGARPKTE 53
           A + P      E  A  EV     +A P +  + P V  P    +A      TGA   T 
Sbjct: 175 AAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTG 234

Query: 54  TKSVP--AARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAV------ 105
               P  +  P+T     + A  K       GA PK  A   TGA PK   + V      
Sbjct: 235 AAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPK--ATSATGAVPKGGGKGVTRSRNG 292

Query: 106 ---GGARSKTDAKAI-PGARPKD-EAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAES 160
               G +SK +   +  G RP D  A A A S  G +A       S+     W    ++S
Sbjct: 293 GKGKGKKSKVEVDELGMGFRPGDGAAAAAAASANGGQAFLAEVPDSEEGESGWTDTESDS 352

Query: 161 GSVTKSKGLSMDRELVNVDAETFP 184
            S  +++     R  V +    FP
Sbjct: 353 DSEPETQRRGRGRRPVAMQKRPFP 376



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 51/214 (23%), Positives = 78/214 (36%), Gaps = 32/214 (14%)

Query: 10  AQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSV-PAARPKTEAQA 68
           A+A+   +AG  +  G       P+    + R Q    A      ++V PAA   + A+A
Sbjct: 51  ARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAA---SSAEA 107

Query: 69  MSGARPKTEVQVMGGARPKTEA-------------QGITGARPKTDARAVGGA------- 108
            SGA  + +     G  PK E+              G+T A    +A A+ GA       
Sbjct: 108 QSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAP 167

Query: 109 -RSKTDAKAI-PGARPKDEAQAWAQSEFG-----TEAVSQAEGV-SQTNAVAWPLATAES 160
             ++T   A+ PG     EA A  +   G        V++A GV S T A   P+    +
Sbjct: 168 REAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPT 227

Query: 161 GSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQP 194
           G+   +          +      PGT   K   P
Sbjct: 228 GAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATP 261


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 49/201 (24%), Positives = 109/201 (54%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           +G  +  + L L+ K  DPFI +++ + +   +     ++ IR  G + +I  ++N    
Sbjct: 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDP 442

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  M +++  Y N   ++ ++ +V ++ +A +++S  Q+ G++ L ++T+T DY
Sbjct: 443 HIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDY 502

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             L+ N ++ F  LL+    + K  +LK+L N +ENP + KKL S +  + F  L+N   
Sbjct: 503 QHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYV 562

Query: 773 TNDNIQIVIKMFQNISNIIKS 793
            ++ +   + +F+ I + +++
Sbjct: 563 ESEILINALTLFEIIYDNLRA 583



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 62/283 (21%), Positives = 94/283 (33%), Gaps = 29/283 (10%)

Query: 2   TGAEIEPSAQAKPEKKAGEEVIAGPERENDV-----PLVVRPKVRTQATTGARPKTETKS 56
           + AE +  A ++ ++  G  V  GP+ E+ V       +  P   T+A   A       +
Sbjct: 103 SSAEAQSGAGSQAQEADGAGV--GPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGA 160

Query: 57  VPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKA 116
              A    EA+    A P   V     A P    +G   A P   A A G A     A+A
Sbjct: 161 PKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEA 220

Query: 117 IPGARPKDEAQAWAQSEF-------------GTEAVSQAEGVSQTNAVAWPLATAESGSV 163
              A P   A     +E              GT A  +A   + T A+  P AT+ +G+V
Sbjct: 221 PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAI--PKATSATGAV 278

Query: 164 TKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESG 223
            K  G  + R       +          +   F PG+         +   A      ++ 
Sbjct: 279 PKGGGKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDGA-------AAAAAASANGGQAF 331

Query: 224 FWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNP 266
                ++    S WT  E+   S P  +   R R     Q  P
Sbjct: 332 LAEVPDSEEGESGWTDTESDSDSEPETQRRGRGRRPVAMQKRP 374



 Score = 37.0 bits (84), Expect = 0.076
 Identities = 53/204 (25%), Positives = 73/204 (35%), Gaps = 25/204 (12%)

Query: 4   AEIEPSAQAKPEKKAGEEV-----IAGPERENDVPLVVRPKVRTQA-----TTGARPKTE 53
           A + P      E  A  EV     +A P +  + P V  P    +A      TGA   T 
Sbjct: 175 AAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTG 234

Query: 54  TKSVP--AARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAV------ 105
               P  +  P+T     + A  K       GA PK  A   TGA PK   + V      
Sbjct: 235 AAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPK--ATSATGAVPKGGGKGVTRSRNG 292

Query: 106 ---GGARSKTDAKAI-PGARPKD-EAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAES 160
               G +SK +   +  G RP D  A A A S  G +A       S+     W    ++S
Sbjct: 293 GKGKGKKSKVEVDELGMGFRPGDGAAAAAAASANGGQAFLAEVPDSEEGESGWTDTESDS 352

Query: 161 GSVTKSKGLSMDRELVNVDAETFP 184
            S  +++     R  V +    FP
Sbjct: 353 DSEPETQRRGRGRRPVAMQKRPFP 376



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 51/214 (23%), Positives = 78/214 (36%), Gaps = 32/214 (14%)

Query: 10  AQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSV-PAARPKTEAQA 68
           A+A+   +AG  +  G       P+    + R Q    A      ++V PAA   + A+A
Sbjct: 51  ARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAA---SSAEA 107

Query: 69  MSGARPKTEVQVMGGARPKTEA-------------QGITGARPKTDARAVGGA------- 108
            SGA  + +     G  PK E+              G+T A    +A A+ GA       
Sbjct: 108 QSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAP 167

Query: 109 -RSKTDAKAI-PGARPKDEAQAWAQSEFG-----TEAVSQAEGV-SQTNAVAWPLATAES 160
             ++T   A+ PG     EA A  +   G        V++A GV S T A   P+    +
Sbjct: 168 REAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPT 227

Query: 161 GSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQP 194
           G+   +          +      PGT   K   P
Sbjct: 228 GAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATP 261


>gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo
           sapiens]
          Length = 284

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 58/250 (23%), Positives = 122/250 (48%), Gaps = 36/250 (14%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+R+L ++T+T D+
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK                          S F+ L++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 214 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 267

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 268 H-HDAEVKEK 276


>gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo
           sapiens]
          Length = 284

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 57/250 (22%), Positives = 122/250 (48%), Gaps = 36/250 (14%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+R+L ++T+T D+
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK                          S F+ L++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQ+I N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 214 AKEILLRVLTLFQHIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 267

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 268 H-HDAEVKEK 276


>gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo
           sapiens]
          Length = 284

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 57/250 (22%), Positives = 122/250 (48%), Gaps = 36/250 (14%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+R+L ++T+T D+
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK                          S F+ L++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQ+I N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 214 AKEILLRVLTLFQHIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 267

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 268 H-HDAEVKEK 276


>gi|238776797 SVH protein isoform e [Homo sapiens]
          Length = 284

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 57/250 (22%), Positives = 121/250 (48%), Gaps = 36/250 (14%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
            ++   L  + +++    N   I+ +I QVCE+  +  ++S  QL G+ +L ++T+T D+
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
             ++ +Y++    +L T N  TK                          S F+ L++   
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVD------------------------SSFLSLYDSHV 213

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 214 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 267

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 268 H-HDAEVKEK 276


>gi|238776799 SVH protein isoform d [Homo sapiens]
          Length = 249

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 56/250 (22%), Positives = 107/250 (42%), Gaps = 71/250 (28%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N    
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKIN---- 113

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
                                               HS  S+++   +  L +L++ ++ 
Sbjct: 114 ------------------------------------HSNQSIKE-KALNALNNLSVNVEN 136

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
              I                  K  VLK+LLNLSENPA+ + L  A+  S F+ L++   
Sbjct: 137 QIKI------------------KVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 178

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 179 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 232

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 233 H-HDAEVKEK 241


>gi|238776795 SVH protein isoform c [Homo sapiens]
          Length = 284

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 56/250 (22%), Positives = 107/250 (42%), Gaps = 71/250 (28%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N    
Sbjct: 93  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKIN---- 148

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDY 712
                                               HS  S+++   +  L +L++ ++ 
Sbjct: 149 ------------------------------------HSNQSIKE-KALNALNNLSVNVEN 171

Query: 713 HTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEE 772
              I                  K  VLK+LLNLSENPA+ + L  A+  S F+ L++   
Sbjct: 172 QIKI------------------KVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 213

Query: 773 TNDNIQIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREF-----EELAKQLQAQID 827
             + +  V+ +FQNI N +K      I+   +++P  +    F     EE A++++A +D
Sbjct: 214 AKEILLRVLTLFQNIKNCLK------IEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVD 267

Query: 828 NQNDPEVGQQ 837
           + +D EV ++
Sbjct: 268 H-HDAEVKEK 276


>gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo
           sapiens]
          Length = 253

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 26/107 (24%), Positives = 56/107 (52%)

Query: 593 IGSEEFEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSS 652
           + +E+ ++ L L++   DP I E + I +G  +A    +  IR+ G + ++   +N+ + 
Sbjct: 58  LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117

Query: 653 RVRTSFLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTG 699
            ++   L  + +++    N   I+ +I QVCE+  +  ++S   LTG
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVLLTG 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,421,253
Number of Sequences: 37866
Number of extensions: 1538244
Number of successful extensions: 6319
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 4922
Number of HSP's gapped (non-prelim): 713
length of query: 838
length of database: 18,247,518
effective HSP length: 111
effective length of query: 727
effective length of database: 14,044,392
effective search space: 10210272984
effective search space used: 10210272984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press