Search of human proteins with 19923403

Search of human proteins with 19923403

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923403 exosome component 2 [Homo sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923403 exosome component 2 [Homo sapiens]                        577   e-165
gi|169167744 PREDICTED: similar to hCG1641913 [Homo sapiens]           31   1.1  
gi|239748517 PREDICTED: similar to hCG1641913 [Homo sapiens]           31   1.1  
gi|169167587 PREDICTED: similar to hCG1641913 [Homo sapiens]           31   1.1  
gi|150456463 gasdermin 1 [Homo sapiens]                                31   1.1  
gi|239754548 PREDICTED: similar to hCG1779533 [Homo sapiens]           30   1.9  
gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]                    29   4.3  
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]           28   7.3  
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]            28   7.3  
gi|122114658 hypothetical protein LOC23053 [Homo sapiens]              28   7.3  
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ...    28   7.3  
gi|70608109 integrator complex subunit 8 [Homo sapiens]                28   7.3  
gi|148539860 protein tyrosine phosphatase, receptor type, T isof...    28   9.6  
gi|148539858 protein tyrosine phosphatase, receptor type, T isof...    28   9.6  
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           28   9.6  
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]           28   9.6  

>gi|19923403 exosome component 2 [Homo sapiens]
          Length = 293

 Score =  577 bits (1487), Expect = e-165
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 60
           MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV
Sbjct: 1   MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 60

Query: 61  ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 120
           ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL
Sbjct: 61  ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 120

Query: 121 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 180
           RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK
Sbjct: 121 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 180

Query: 181 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 240
           RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC
Sbjct: 181 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 240

Query: 241 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 293
           IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG
Sbjct: 241 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 293


>gi|169167744 PREDICTED: similar to hCG1641913 [Homo sapiens]
          Length = 506

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 20/58 (34%), Positives = 26/58 (44%)

Query: 112 SMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQG 169
           S    GG   R ++E  L   G+ + G+LI A + AV S      HTR    G  G G
Sbjct: 137 SREYEGGRRARCTSEYVLNPEGWPRPGELIPAGLGAVVSSDQAGQHTRRRVEGDFGSG 194


>gi|239748517 PREDICTED: similar to hCG1641913 [Homo sapiens]
          Length = 506

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 20/58 (34%), Positives = 26/58 (44%)

Query: 112 SMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQG 169
           S    GG   R ++E  L   G+ + G+LI A + AV S      HTR    G  G G
Sbjct: 137 SREYEGGRRARCTSEYVLNPEGWPRPGELIPAGLGAVVSSDQAGQHTRRRVEGDFGSG 194


>gi|169167587 PREDICTED: similar to hCG1641913 [Homo sapiens]
          Length = 506

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 20/58 (34%), Positives = 26/58 (44%)

Query: 112 SMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQG 169
           S    GG   R ++E  L   G+ + G+LI A + AV S      HTR    G  G G
Sbjct: 137 SREYEGGRRARCTSEYVLNPEGWPRPGELIPAGLGAVVSSDQAGQHTRRRVEGDFGSG 194


>gi|150456463 gasdermin 1 [Homo sapiens]
          Length = 445

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)

Query: 79  EVGDIVVGRIT---EVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFL 135
           +VGD+  G  T   EVQ++  +VE  SR+    LLSS++   G+ ++   + ELA+ G L
Sbjct: 249 DVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGK-KKELQDLELALEGAL 307

Query: 136 QEGDLISAE 144
            +G  ++ E
Sbjct: 308 DKGHEVTLE 316


>gi|239754548 PREDICTED: similar to hCG1779533 [Homo sapiens]
          Length = 161

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 18/44 (40%), Positives = 23/44 (52%)

Query: 93  QKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQ 136
           Q R K  ++  L + LL   MN P  +LR  SA   LA +G LQ
Sbjct: 65  QCRPKTSSSQTLQACLLPGGMNRPSFDLRTASAGPALASQGLLQ 108


>gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]
          Length = 501

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 3/69 (4%)

Query: 210 EHKEEEAGGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCY---EASLPH 266
           +H  ++   F AN+   S+ D E + R  N  I   TQ+ +      +Y     E  LP 
Sbjct: 95  DHASKQMVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPL 154

Query: 267 QIKDILKPE 275
           Q+ D ++PE
Sbjct: 155 QLDDAVRPE 163


>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
          Length = 541

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 9/139 (6%)

Query: 47  MGEEKLIASVAGSVERVNKLICVKALK-TRYIGEVGDIVVGRITEVQQKRWKVETNSRLD 105
           +  +  I  ++  +ER N  IC   L+  R    V D+V   +T +Q+++ K E     +
Sbjct: 200 LSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEE--KLRE 257

Query: 106 SVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSL---HTRSL- 161
           S  LL ++     EL+      E  +     + + +  +V+A  +  AV        SL 
Sbjct: 258 SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAIRPREESLA 317

Query: 162 --KYGKLGQGVLVQVSPSL 178
             KY   GQG L  V   L
Sbjct: 318 EKKYTSQGQGDLDSVLSQL 336


>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
          Length = 703

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 9/139 (6%)

Query: 47  MGEEKLIASVAGSVERVNKLICVKALK-TRYIGEVGDIVVGRITEVQQKRWKVETNSRLD 105
           +  +  I  ++  +ER N  IC   L+  R    V D+V   +T +Q+++ K E     +
Sbjct: 200 LSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEE--KLRE 257

Query: 106 SVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSL---HTRSL- 161
           S  LL ++     EL+      E  +     + + +  +V+A  +  AV        SL 
Sbjct: 258 SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAIRPREESLA 317

Query: 162 --KYGKLGQGVLVQVSPSL 178
             KY   GQG L  V   L
Sbjct: 318 EKKYTSQGQGDLDSVLSQL 336


>gi|122114658 hypothetical protein LOC23053 [Homo sapiens]
          Length = 1842

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 12/20 (60%), Positives = 16/20 (80%)

Query: 269  KDILKPEIMEEIVMETRQRL 288
            K +L P +++EIVMET QRL
Sbjct: 1729 KGVLSPFVLQEIVMETLQRL 1748


>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
           [Homo sapiens]
          Length = 501

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 11/78 (14%)

Query: 204 WIYPTPEHKEE--EAGGFIANLE---PVSLADREVISRLRNCIISLVTQRMMLYDTSILY 258
           W  P   H E   ++ G+ A  E   P SL  R  +         L    M L+ T++L 
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGE------HLARMEMFLFFTALLQ 467

Query: 259 CYEASLPHQIKDILKPEI 276
            +    PH++   LKP +
Sbjct: 468 RFHLHFPHELVPDLKPRL 485


>gi|70608109 integrator complex subunit 8 [Homo sapiens]
          Length = 995

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 8/124 (6%)

Query: 80  VGDIVVGRITEVQQKRWKVETNS-RLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEG 138
           V DI+ GR   VQ  +  +  N  ++D +L + S ++    L + S   +  M  FL+  
Sbjct: 390 VRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSV---NLEKASESLKGNMAAFLKNV 446

Query: 139 DLISAEVQAVFSDGAVSLHTRSLK--YGKLGQGVLVQVSP--SLVKRQKTHFHDLPCGAS 194
            L   ++Q VF   +  L    LK    KL    + + SP  +L  +  T F+D+P  AS
Sbjct: 447 CLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASAS 506

Query: 195 VILG 198
           V +G
Sbjct: 507 VNIG 510


>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
            precursor [Homo sapiens]
          Length = 1441

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)

Query: 187  HDLPCGASVILGNNGFIWIYPTPE------HKEEEAGG---FIANLEPVSLADREVISRL 237
            H +PC A+ +LG    +     PE      H    AG    FIA    + +A+ E +  +
Sbjct: 1053 HGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDI 1112

Query: 238  RNCIISLVTQRMMLYDTSILYCY 260
             NC+  L  QR+ L  T   Y +
Sbjct: 1113 FNCVRELRAQRVNLVQTEEQYVF 1135


>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
            precursor [Homo sapiens]
          Length = 1460

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)

Query: 187  HDLPCGASVILGNNGFIWIYPTPE------HKEEEAGG---FIANLEPVSLADREVISRL 237
            H +PC A+ +LG    +     PE      H    AG    FIA    + +A+ E +  +
Sbjct: 1072 HGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDI 1131

Query: 238  RNCIISLVTQRMMLYDTSILYCY 260
             NC+  L  QR+ L  T   Y +
Sbjct: 1132 FNCVRELRAQRVNLVQTEEQYVF 1154


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 8/143 (5%)

Query: 47  MGEEKLIASVAGSVERVNKLICVKALK-TRYIGEVGDIVVGRITEVQQKRWKVETNSRLD 105
           +  +  I  ++  +ER N  IC   L+  R    V D+V   +T +Q+++ K E     +
Sbjct: 200 LSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEE--KLRE 257

Query: 106 SVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAV---SLHTRSLK 162
           S  LL ++     EL+      E  +     + + +  +V+A  +  AV   SL + S  
Sbjct: 258 SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAISLESVSAT 317

Query: 163 YGKLGQGVLVQVSPSLVKRQKTH 185
             +L Q ++ +     +KR + H
Sbjct: 318 CKQLSQELMEKYEE--LKRMEAH 338


>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
          Length = 495

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 8/143 (5%)

Query: 47  MGEEKLIASVAGSVERVNKLICVKALK-TRYIGEVGDIVVGRITEVQQKRWKVETNSRLD 105
           +  +  I  ++  +ER N  IC   L+  R    V D+V   +T +Q+++ K E     +
Sbjct: 200 LSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEE--KLRE 257

Query: 106 SVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAV---SLHTRSLK 162
           S  LL ++     EL+      E  +     + + +  +V+A  +  AV   SL + S  
Sbjct: 258 SEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAISLESVSAT 317

Query: 163 YGKLGQGVLVQVSPSLVKRQKTH 185
             +L Q ++ +     +KR + H
Sbjct: 318 CKQLSQELMEKYEE--LKRMEAH 338


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,587,836
Number of Sequences: 37866
Number of extensions: 446692
Number of successful extensions: 994
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 987
Number of HSP's gapped (non-prelim): 19
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.