Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 198041734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
(622 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 1232 0.0
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 1232 0.0
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 1232 0.0
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 946 0.0
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 811 0.0
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 811 0.0
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 811 0.0
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 794 0.0
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 743 0.0
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 741 0.0
gi|91825557 kinesin light chain 3 [Homo sapiens] 506 e-143
gi|19923891 kinesin-like 8 isoform c [Homo sapiens] 375 e-104
gi|34304360 nephrocystin 3 [Homo sapiens] 146 5e-35
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 56 1e-07
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 55 2e-07
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 55 3e-07
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 54 6e-07
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 54 6e-07
gi|22749211 transmembrane and tetratricopeptide repeat containin... 50 8e-06
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 46 9e-05
gi|83415184 transmembrane and tetratricopeptide repeat containin... 45 2e-04
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 42 0.001
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 42 0.002
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 42 0.002
gi|116089276 tetratricopeptide repeat domain 23-like [Homo sapiens] 41 0.004
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 40 0.006
gi|148746195 trichohyalin [Homo sapiens] 40 0.008
gi|55749678 ninein-like [Homo sapiens] 39 0.011
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 39 0.014
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 39 0.019
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 1232 bits (3188), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL
Sbjct: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
Query: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP
Sbjct: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
Query: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
Query: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
Query: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP
Sbjct: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
Query: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE
Sbjct: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
Query: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL
Sbjct: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
Query: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG
Sbjct: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
Query: 601 LSDSRTLSSSSMDLSRRSSLVG 622
LSDSRTLSSSSMDLSRRSSLVG
Sbjct: 601 LSDSRTLSSSSMDLSRRSSLVG 622
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 1232 bits (3188), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL
Sbjct: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
Query: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP
Sbjct: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
Query: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
Query: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
Query: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP
Sbjct: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
Query: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE
Sbjct: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
Query: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL
Sbjct: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
Query: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG
Sbjct: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
Query: 601 LSDSRTLSSSSMDLSRRSSLVG 622
LSDSRTLSSSSMDLSRRSSLVG
Sbjct: 601 LSDSRTLSSSSMDLSRRSSLVG 622
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 1232 bits (3188), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL
Sbjct: 61 LRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKL 120
Query: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP
Sbjct: 121 QRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSP 180
Query: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA
Sbjct: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
Query: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE
Sbjct: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
Query: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP
Sbjct: 301 AEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGP 360
Query: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE
Sbjct: 361 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
Query: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK
Sbjct: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRK 480
Query: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL
Sbjct: 481 QGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDGSGSL 540
Query: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG
Sbjct: 541 RRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQPGGTG 600
Query: 601 LSDSRTLSSSSMDLSRRSSLVG 622
LSDSRTLSSSSMDLSRRSSLVG
Sbjct: 601 LSDSRTLSSSSMDLSRRSSLVG 622
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 946 bits (2446), Expect = 0.0
Identities = 477/524 (91%), Positives = 489/524 (93%), Gaps = 1/524 (0%)
Query: 100 RRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDED-ASPNEEKGD 158
+ ++Q + LR E L E A+ +++ +L + ++ EEKGD
Sbjct: 22 KAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQEEKGD 81
Query: 159 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 218
VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV
Sbjct: 82 VPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAV 141
Query: 219 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 278
PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH
Sbjct: 142 PLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDH 201
Query: 279 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 338
PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG
Sbjct: 202 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 261
Query: 339 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 398
KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE
Sbjct: 262 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Query: 399 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 458
KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL
Sbjct: 322 KEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGAL 381
Query: 459 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 518
YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR
Sbjct: 382 YRRQGKLEAAHTLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR 441
Query: 519 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 578
SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK
Sbjct: 442 SESDLEDVGPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMK 501
Query: 579 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 622
RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG
Sbjct: 502 RASSLNFLNKSVEEPTQPGGTGLSDSRTLSSSSMDLSRRSSLVG 545
Score = 221 bits (563), Expect = 2e-57
Identities = 169/420 (40%), Positives = 213/420 (50%), Gaps = 58/420 (13%)
Query: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL
Sbjct: 1 MAMMVFPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCIL 60
Query: 61 LRRSLEAIELGLGEAQ-----VILALSSHLGAVESEKQ---------------------K 94
LRRSLEAIELGLGEAQ V L E E+ +
Sbjct: 61 LRRSLEAIELGLGEAQEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPAR 120
Query: 95 LRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH-----LLFMSQIRKLDED 149
LR ++Q R E+A + +QA+ LE+ H ++ + + D
Sbjct: 121 LRTLHNLVIQYASQGRYEVA-----VPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD 175
Query: 150 ASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYA 209
+ +E + D L + PA + A L L + Y
Sbjct: 176 QNKYKEAAHLLNDALAIREKTLGKDHPA----------------VAATLNNL---AVLYG 216
Query: 210 SQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 269
+G+Y+ A PLCK+ALE EK G HPDVA L+ LAL+ ++Q K +E + AL I
Sbjct: 217 KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
Query: 270 REKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRAL-EIREKVLGKFHPDVAKQLS 328
LG D P VA T NNLA Y K+GKY++AE L K L EK G + D
Sbjct: 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWM 336
Query: 329 NLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 388
+ +++ K + Y A ++ D P V T +L + Y +QGK + A TL
Sbjct: 337 HAEEREESKDKRRDSAPYGEYGSWYKACKV--DSPTVNTTLRSLGALYRRQGKLEAAHTL 394
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 30 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 89
Query: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 90 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 149
Query: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 150 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 209
Query: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 210 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 269
Query: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 270 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 329
Query: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 330 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 389
Query: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 390 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 449
Query: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 450 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 509
Query: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 510 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 563
Query: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 564 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 615
Query: 597 GGTGLSDSRTLSSSSMDLSRRS 618
L SR LS+S+MDLS S
Sbjct: 616 SAAPLQVSRGLSASTMDLSSSS 637
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
Query: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
Query: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
Query: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 311
Query: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 312 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 371
Query: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 372 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 431
Query: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 432 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 491
Query: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 492 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 545
Query: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 546 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 597
Query: 597 GGTGLSDSRTLSSSSMDLSRRS 618
L SR LS+S+MDLS S
Sbjct: 598 SAAPLQVSRGLSASTMDLSSSS 619
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 811 bits (2095), Expect = 0.0
Identities = 432/622 (69%), Positives = 486/622 (78%), Gaps = 24/622 (3%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
Query: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
Query: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
Query: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKY 298
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAVAATLNNLAVLYGKRGKY
Sbjct: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKY 311
Query: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
KEAEPLC+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E VE YY+RAL IY +L
Sbjct: 312 KEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYYQRALAIYEGQL 371
Query: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEER 418
GPD+PNVA+TKNNLASCYLKQGKY +AETLYKEILTRAH +EFGSV+ D+KPIWMHAEER
Sbjct: 372 GPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDDHKPIWMHAEER 431
Query: 419 EESKDKR--RDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCAS 476
EE R PY EYG WYKACKV SPTVNTTLR+LGALYRRQGKLEAA TLE+CA
Sbjct: 432 EEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKLEAAETLEECAL 491
Query: 477 RNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDLEDVGPTAEWNGDG 536
R+R+QG DP SQTKV ELL + GRR + D G ED EW+GDG
Sbjct: 492 RSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGG------EDASVAVEWSGDG 545
Query: 537 SGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPRMKRASSLNFLNKSVEEPTQP 596
SG+L+RSGS GK+RD LRRSSE+LV+KLQG P+ P + MKRA+SLN+LN QP
Sbjct: 546 SGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPR-PSSSNMKRAASLNYLN-------QP 597
Query: 597 GGTGLSDSRTLSSSSMDLSRRS 618
L SR LS+S+MDLS S
Sbjct: 598 SAAPLQVSRGLSASTMDLSSSS 619
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 794 bits (2051), Expect = 0.0
Identities = 417/605 (68%), Positives = 486/605 (80%), Gaps = 18/605 (2%)
Query: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
Query: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
Query: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
Query: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
Query: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
Query: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
Query: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
Query: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
Query: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
Query: 527 GPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQ--EPPNPRMKRASSLN 584
+ EWNGDG+GSL+RSGSF KLR ++RRSSE LV+KL+GG+ + EP NP A L
Sbjct: 543 SMSVEWNGDGTGSLKRSGSFSKLRASIRRSSEKLVRKLKGGSSRESEPKNPGASLAEPLF 602
Query: 585 FLNKS 589
N S
Sbjct: 603 VENDS 607
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 743 bits (1918), Expect = 0.0
Identities = 387/552 (70%), Positives = 448/552 (81%), Gaps = 16/552 (2%)
Query: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
Query: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
Query: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
Query: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
Query: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
Query: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
Query: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
Query: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
Query: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
Query: 527 GPTAEWNGDGSG 538
+ EWNG SG
Sbjct: 543 SMSVEWNGGVSG 554
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 741 bits (1912), Expect = 0.0
Identities = 385/548 (70%), Positives = 446/548 (81%), Gaps = 16/548 (2%)
Query: 1 MAMMVFPRE---EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAP----EAGEAEPG 53
M+ MV+ +E EKL+QDEI+ TK VIQGLE L+ EH ++L L+ + +
Sbjct: 5 MSTMVYIKEDKLEKLTQDEIISKTKQVIQGLEALKNEHNSILQSLLETLKCLKKDDESNL 64
Query: 54 SQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREEL 113
+E+ ++R+SLE +ELGL EAQV++ALS+HL AVESEKQKLRAQVRRL QENQWLR+EL
Sbjct: 65 VEEKSNMIRKSLEMLELGLSEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDEL 124
Query: 114 AGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKG-DVPKDTLDDLFPNED 172
A TQQKLQ+SEQ+VAQLEEEK+HL FM+Q++K D+D SP+E+K D K+ LDDLFPN++
Sbjct: 125 ANTQQKLQKSEQSVAQLEEEKKHLEFMNQLKKYDDDISPSEDKDTDSTKEPLDDLFPNDE 184
Query: 173 E---QSPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 229
+ Q + Q GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE
Sbjct: 185 DDPGQGIQQQHSSAAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLE 244
Query: 230 KTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA 289
KTSGHDHPDVATMLNILALVYRDQNKYK+AA+LLNDALAIREKTLGKDHPAVAATLNNLA
Sbjct: 245 KTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLA 304
Query: 290 VLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 349
VLYGKRGKYKEAEPLCKRALEIREKVLGK HPDVAKQL+NLALLCQNQGK EEVEYYY+R
Sbjct: 305 VLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 364
Query: 350 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNK 409
ALEIY T+LGPDDPNVAKTKNNLASCYLKQGK++ AETLYKEILTRAHE+EFGSV+ +NK
Sbjct: 365 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENK 424
Query: 410 PIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAH 469
PIWMHAEEREE K K++D +GEYG WYKACKVDSPTV TTL++LGALYRRQGK EAA
Sbjct: 425 PIWMHAEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAE 484
Query: 470 TLEDCASRNRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPRSESDL---EDV 526
TLE+ A R+RKQGLD + +V E+L D ++R SR+ + ES E+V
Sbjct: 485 TLEEAAMRSRKQGLDNVHKQRVAEVLNDPENM--EKRRSRESLNVDVVKYESGPDGGEEV 542
Query: 527 GPTAEWNG 534
+ EWNG
Sbjct: 543 SMSVEWNG 550
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 506 bits (1302), Expect = e-143
Identities = 270/428 (63%), Positives = 319/428 (74%), Gaps = 6/428 (1%)
Query: 10 EKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGS----QERCILLRRSL 65
E+LS +E+V T+ V+QGLE LR EH L L AG+ +E+ ++ SL
Sbjct: 16 ERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSL 75
Query: 66 EAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQ 125
EAIELGLGEAQV+LALS+H+GA+E+EKQ+LR+Q RRL QEN WLREEL TQ++L+ SE+
Sbjct: 76 EAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEE 135
Query: 126 AVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDV 185
+VAQLEEEK+HL F+ Q+R+ D A + + +D+L LFP+E+E+ P G
Sbjct: 136 SVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKGPEAAGA-A 194
Query: 186 SGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNI 245
+ Q GGYEIPARLRTLHNLVIQYA QGRYEVAVPLC+QALEDLE++SGH HPDVATMLNI
Sbjct: 195 AAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNI 254
Query: 246 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 305
LALVYRDQNKYKEA LL+DAL IRE+TLG +HPAVAATLNNLAVLYGKRG+Y+EAEPLC
Sbjct: 255 LALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLC 314
Query: 306 KRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNV 365
+RALEIREKVLG HPDVAKQL+NLALLCQNQGK E+VE +Y RAL IY GP DPNV
Sbjct: 315 QRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNV 374
Query: 366 AKTKNNLASCYLKQGKYQDAETLYKEILTRAH-EKEFGSVNGDNKPIWMHAEEREESKDK 424
AKTKNNLAS YLKQ KYQ AE LYKEIL + G+ N A R S K
Sbjct: 375 AKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSK 434
Query: 425 RRDSAPYG 432
R+S G
Sbjct: 435 IRESIRRG 442
Score = 67.8 bits (164), Expect = 3e-11
Identities = 94/344 (27%), Positives = 132/344 (38%), Gaps = 94/344 (27%)
Query: 321 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 380
P + L NL + QG+ E R+ALE G P+VA N LA Y Q
Sbjct: 204 PARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQN 263
Query: 381 KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKA 440
KY++A L + L + E+ G
Sbjct: 264 KYKEATDLLHDAL-QIREQTLGP------------------------------------- 285
Query: 441 CKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGL-----DPASQTKVVELL 495
+ P V TL +L LY ++G+ A L A R++ L D A Q + LL
Sbjct: 286 ---EHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALL 342
Query: 496 KDGSGRRGD--RRSSRDMA---GGAGP------RSESDL--------------------- 523
G+ D R +R ++ GP +++++L
Sbjct: 343 CQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEIL 402
Query: 524 --EDV-----GPTAEWNGDGSGSLRRSGSFGKLRDALRRSSEMLVKKLQGGTPQEPPNPR 576
ED+ P GD +LRRS S K+R+++RR SE LV +L+G
Sbjct: 403 HKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEAAAGAAG-- 460
Query: 577 MKRASSLNFLNKSVEEPTQPGGTGLS-----DSRTLSSSSMDLS 615
MKRA SLN LN V+ P PG S RTLS+S+ DLS
Sbjct: 461 MKRAMSLNTLN--VDAPRAPGTQFPSWHLDKAPRTLSASTQDLS 502
>gi|19923891 kinesin-like 8 isoform c [Homo sapiens]
Length = 315
Score = 375 bits (962), Expect = e-104
Identities = 200/284 (70%), Positives = 227/284 (79%), Gaps = 8/284 (2%)
Query: 7 PREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPL-----VAPEAGEAEPGSQERCILL 61
P +LSQ+EI+ T+ V QGLE LR EH+A+L L + G E E+ L
Sbjct: 12 PAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHEEGLVHEKARQL 71
Query: 62 RRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQ 121
RRS+E IELGL EAQV+LAL+SHL VESEKQKLRAQVRRL QENQWLR+ELAGTQQ+LQ
Sbjct: 72 RRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLRDELAGTQQRLQ 131
Query: 122 RSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEK-GDVPKDTLDDLFPNEDEQSPAP-- 178
RSEQAVAQLEEEK+HL F+ Q+R+ DED +EEK GD KD+LDDLFPNE+E+ P+
Sbjct: 132 RSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFPNEEEEDPSNGL 191
Query: 179 SPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 238
S G G + Q GGYEIPARLRTLHNLVIQYA+QGRYEVAVPLCKQALEDLE+TSG HPD
Sbjct: 192 SRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 251
Query: 239 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVA 282
VATMLNILALVYRDQNKYKEAAHLLNDAL+IRE TLG DHPAV+
Sbjct: 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 78.6 bits (192), Expect = 2e-14
Identities = 41/92 (44%), Positives = 58/92 (63%)
Query: 275 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLC 334
G + PA TL+NL + Y +G+Y+ A PLCK+ALE E+ G+ HPDVA L+ LAL+
Sbjct: 204 GYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVY 263
Query: 335 QNQGKAEEVEYYYRRALEIYATRLGPDDPNVA 366
++Q K +E + AL I + LGPD P V+
Sbjct: 264 RDQNKYKEAAHLLNDALSIRESTLGPDHPAVS 295
Score = 35.0 bits (79), Expect = 0.21
Identities = 24/74 (32%), Positives = 34/74 (45%)
Query: 321 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 380
P + L NL + QG+ E ++ALE G P+VA N LA Y Q
Sbjct: 208 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQN 267
Query: 381 KYQDAETLYKEILT 394
KY++A L + L+
Sbjct: 268 KYKEAAHLLNDALS 281
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 146 bits (369), Expect = 5e-35
Identities = 108/308 (35%), Positives = 144/308 (46%), Gaps = 37/308 (12%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P ++LH L Y ++ A L KQALE E G DHP A L LA +Y+ QN
Sbjct: 982 PRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQN 1041
Query: 255 KYKEAAH------------------------LLNDALAIREKTLGKDHPAVAATLNNLAV 290
KY++A H L AL + E TLGKD P A TLN L V
Sbjct: 1042 KYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGV 1101
Query: 291 LYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRA 350
LY + + A+ KR+LE+RE+VLG HPD A+ L+NLA LC + + ++ E Y RA
Sbjct: 1102 LYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEELYERA 1161
Query: 351 LEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKP 410
L+I L PD P++A T +LA Y K GK A LY E+ +K FG +
Sbjct: 1162 LDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLY-ELAVEIRQKSFGPKHPSVAT 1220
Query: 411 IWMHAEEREESKDKRRDSAPYGEYGSWYKACKV--DS-----PTVNTTLRSLGALYRRQG 463
++ K ++ P E +A K+ DS P V TL++L L G
Sbjct: 1221 ALVNLAVLYSQMKKHVEALPLYE-----RALKIYEDSLGRMHPRVGETLKNLAVLSYEGG 1275
Query: 464 KLEAAHTL 471
E A L
Sbjct: 1276 DFEKAAEL 1283
Score = 141 bits (355), Expect = 2e-33
Identities = 83/203 (40%), Positives = 111/203 (54%)
Query: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
G + P RTL+ L + Y Q E A K++LE E+ G DHPD A LN LA +
Sbjct: 1086 GKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALC 1145
Query: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
++ +Y +A L AL IR + L DHP++A T+ +LA+LY K GK +A PL + A+E
Sbjct: 1146 NEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVE 1205
Query: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
IR+K G HP VA L NLA+L K E Y RAL+IY LG P V +T
Sbjct: 1206 IRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLK 1265
Query: 371 NLASCYLKQGKYQDAETLYKEIL 393
NLA + G ++ A LYK +
Sbjct: 1266 NLAVLSYEGGDFEKAAELYKRAM 1288
Score = 119 bits (299), Expect = 6e-27
Identities = 82/246 (33%), Positives = 120/246 (48%), Gaps = 25/246 (10%)
Query: 184 DVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVA------------------------VP 219
++S G + P R L L Y Q +YE A
Sbjct: 1013 EISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFAL 1072
Query: 220 LCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHP 279
L ++AL+ E T G D PD A LN L ++Y QN + A L +L +RE+ LG DHP
Sbjct: 1073 LRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHP 1132
Query: 280 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGK 339
A +LNNLA L ++ +Y +AE L +RAL+IR + L HP +A + +LA+L + GK
Sbjct: 1133 DCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGK 1192
Query: 340 AEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEK 399
++ Y A+EI GP P+VA NLA Y + K+ +A LY+ L + +E
Sbjct: 1193 LDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERAL-KIYED 1251
Query: 400 EFGSVN 405
G ++
Sbjct: 1252 SLGRMH 1257
Score = 115 bits (287), Expect = 2e-25
Identities = 91/295 (30%), Positives = 130/295 (44%), Gaps = 66/295 (22%)
Query: 215 EVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 274
+ VPL +++LE E DHP VA L+ LA VY K+ A L AL I E
Sbjct: 961 QAIVPL-QRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAY 1019
Query: 275 GKDHPAVAATLNNLAVLYGKRGKYKEAEP------------------------LCKRALE 310
G DHP A L LA LY K+ KY++AE L +RAL+
Sbjct: 1020 GADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQ 1079
Query: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
+ E LGK PD A+ L+ L +L Q E + + +R+LE+ LGPD P+ A++ N
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLN 1139
Query: 371 NLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAP 430
NLA+ ++ +Y AE LY E + D RR
Sbjct: 1140 NLAALCNEKKQYDKAEELY-----------------------------ERALDIRR---- 1166
Query: 431 YGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQGLDP 485
+A D P++ T++ L LY++ GKL+ A L + A R++ P
Sbjct: 1167 --------RALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGP 1213
Score = 108 bits (271), Expect = 1e-23
Identities = 63/163 (38%), Positives = 94/163 (57%)
Query: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
G + P ++L+NL + +Y+ A L ++AL+ + DHP +A + LA++Y
Sbjct: 1128 GPDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILY 1187
Query: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
+ K +A L A+ IR+K+ G HP+VA L NLAVLY + K+ EA PL +RAL+
Sbjct: 1188 KKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALK 1247
Query: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 353
I E LG+ HP V + L NLA+L G E+ Y+RA+EI
Sbjct: 1248 IYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEI 1290
Score = 90.1 bits (222), Expect = 5e-18
Identities = 52/119 (43%), Positives = 72/119 (60%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P+ T+ +L I Y G+ + AVPL + A+E +K+ G HP VAT L LA++Y
Sbjct: 1174 PSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMK 1233
Query: 255 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 313
K+ EA L AL I E +LG+ HP V TL NLAVL + G +++A L KRA+EI+E
Sbjct: 1234 KHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKE 1292
Score = 43.1 bits (100), Expect = 8e-04
Identities = 25/81 (30%), Positives = 44/81 (54%)
Query: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
G + P+ L NL + Y+ ++ A+PL ++AL+ E + G HP V L LA++
Sbjct: 1212 GPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLS 1271
Query: 251 RDQNKYKEAAHLLNDALAIRE 271
+ +++AA L A+ I+E
Sbjct: 1272 YEGGDFEKAAELYKRAMEIKE 1292
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/222 (24%), Positives = 101/222 (45%), Gaps = 39/222 (17%)
Query: 181 GGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVA 240
GGG + EI +L ++ YA+Q R E AV + + LE+
Sbjct: 289 GGGMKQEDNAIIEISLKLASI------YAAQNRQEFAVAGYEFCISTLEE---------- 332
Query: 241 TMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLA--VLYGKRGKY 298
K + L D +++ EK H + L+ A +L+ K+
Sbjct: 333 --------------KIEREKELAEDIMSVEEKA--NTHLLLGMCLDACARYLLFSKQPS- 375
Query: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRL 358
+A+ + ++AL+I E++ G+ HP +S+LA QG+ +E Y +RA ++ A ++
Sbjct: 376 -QAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDL-ARQI 433
Query: 359 GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 400
+ P + +NLA+ + + +Y A+ +Y+E L +A K+
Sbjct: 434 --NHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKK 473
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 55.1 bits (131), Expect = 2e-07
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 211 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 270
QG + L +AL G H + L +LA ++ Y EA A+ +
Sbjct: 991 QGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS 1050
Query: 271 EKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNL 330
E+ +G +HP +LA+ + A L RA + V G+ HP++A +N+
Sbjct: 1051 ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNI 1110
Query: 331 ALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA----- 385
L+ + + + AL + GP VA + + +A Y + +++ A
Sbjct: 1111 GLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEK 1170
Query: 386 --ETLYKEILTRAHEK 399
T+YK L HEK
Sbjct: 1171 EGYTIYKTQLGEDHEK 1186
Score = 49.3 bits (116), Expect = 1e-05
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 25/268 (9%)
Query: 191 GYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVY 250
G E P ++ +L + + + A+ L +A + G DHP++A + N + LV
Sbjct: 1055 GTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVL 1114
Query: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
+Y + L +ALA+ K G VA + + +A +Y + +++ A K
Sbjct: 1115 HGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYT 1174
Query: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
I + LG+ H + L L Q + R EIY + P + T
Sbjct: 1175 IYKTQLGEDHEKTKESSEYLKCLTQ------QAVALQRTMNEIYRNGSSANIPPLKFTAP 1228
Query: 371 NLASCYLKQG----------KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREE 420
++AS + +D E L E+ R H+ + S N D E
Sbjct: 1229 SMASVLEQLNVINGILFIPLSQKDLENLKAEV-ARRHQLQEASRNRDR-------AEEPM 1280
Query: 421 SKDKRRDSAPYGEYGSWYKACKVDSPTV 448
+ + AP G+ GS A K SP+V
Sbjct: 1281 ATEPAPAGAP-GDLGSQPPAAKDPSPSV 1307
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 5/167 (2%)
Query: 212 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRE 271
G Y A+ ++A+ E+ G +HP+ LAL ++ A LL A +
Sbjct: 1034 GDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLML 1093
Query: 272 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA 331
G+DHP +A NN+ ++ +Y + + AL + K G VA +A
Sbjct: 1094 LVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVA 1153
Query: 332 LLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLK 378
+ +++ + + + IY T+LG D KTK +S YLK
Sbjct: 1154 RVYESKAEFRSALQHEKEGYTIYKTQLGEDH---EKTKE--SSEYLK 1195
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 54.7 bits (130), Expect = 3e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 205 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 253
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
Query: 254 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 313
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
Query: 314 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 372
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
Query: 373 ASCYLKQGKYQ 383
Y G Y+
Sbjct: 521 IKLYNSIGNYE 531
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 261
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
Query: 262 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
L ++AI +K G+ + + L LY G Y++
Sbjct: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 53.5 bits (127), Expect = 6e-07
Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 24/157 (15%)
Query: 237 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 296
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 246 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 297
Query: 297 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
EAE AL + P A L+NLA + + QG EE YR+ALE++
Sbjct: 298 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 347
Query: 357 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 393
P A +NLAS +QGK Q+A YKE +
Sbjct: 348 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 378
Score = 53.1 bits (126), Expect = 7e-07
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 24/154 (15%)
Query: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 262
NL Y QG ++A+ ++A+E P LA +++ EA
Sbjct: 254 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 305
Query: 263 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 322
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 306 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 349
Query: 323 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
A SNLA + Q QGK +E +Y+ A+ I T
Sbjct: 350 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 383
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/200 (26%), Positives = 81/200 (40%), Gaps = 32/200 (16%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 314 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 365
Query: 255 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
K +EA +A+ I P A +N+ + + A RA++I
Sbjct: 366 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 414
Query: 315 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 374
+P A SNLA + ++ G E YR AL +L PD P+ NLA
Sbjct: 415 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 461
Query: 375 CYLKQGKYQDAETLYKEILT 394
C + D + K++++
Sbjct: 462 CLQIVCDWTDYDERMKKLVS 481
Score = 37.7 bits (86), Expect = 0.032
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 32/226 (14%)
Query: 237 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 296
PD +L +L+ ++ + +AH LAI K +P +A +NL +Y +RG
Sbjct: 42 PDNTGVLLLLSSIHFQCRRLDRSAHF--STLAI------KQNPLLAEAYSNLGNVYKERG 93
Query: 297 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
+ +EA + AL ++ PD NLA G E Y AL+
Sbjct: 94 QLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 142
Query: 357 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY-KEILTRAH----EKEFGSVNGDNKPI 411
+P++ +++L + G+ ++A+ Y K I T+ + G V I
Sbjct: 143 -----NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 197
Query: 412 WM--HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 455
W+ H E+ + D A Y G+ K ++ V LR+L
Sbjct: 198 WLAIHHFEKAVTLDPNFLDA-YINLGNVLKEARIFDRAVAAYLRAL 242
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 53.5 bits (127), Expect = 6e-07
Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 24/157 (15%)
Query: 237 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 296
P+ A + LA VY +Q A A+ ++ P NLA ++G
Sbjct: 256 PNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ--------PHFPDAYCNLANALKEKG 307
Query: 297 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
EAE AL + P A L+NLA + + QG EE YR+ALE++
Sbjct: 308 SVAEAEDCYNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF-- 357
Query: 357 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 393
P A +NLAS +QGK Q+A YKE +
Sbjct: 358 ------PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 388
Score = 53.1 bits (126), Expect = 7e-07
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 24/154 (15%)
Query: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHL 262
NL Y QG ++A+ ++A+E P LA +++ EA
Sbjct: 264 NLACVYYEQGLIDLAIDTYRRAIEL--------QPHFPDAYCNLANALKEKGSVAEAEDC 315
Query: 263 LNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 322
N AL + P A +LNNLA + ++G +EA L ++ALE+ P+
Sbjct: 316 YNTALRLC--------PTHADSLNNLANIKREQGNIEEAVRLYRKALEV--------FPE 359
Query: 323 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
A SNLA + Q QGK +E +Y+ A+ I T
Sbjct: 360 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/200 (26%), Positives = 81/200 (40%), Gaps = 32/200 (16%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P +L+NL QG E AV L ++ALE P+ A + LA V + Q
Sbjct: 324 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQG 375
Query: 255 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
K +EA +A+ I P A +N+ + + A RA++I
Sbjct: 376 KLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI--- 424
Query: 315 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 374
+P A SNLA + ++ G E YR AL +L PD P+ NLA
Sbjct: 425 -----NPAFADAHSNLASIHKDSGNIPEAIASYRTAL-----KLKPDFPD---AYCNLAH 471
Query: 375 CYLKQGKYQDAETLYKEILT 394
C + D + K++++
Sbjct: 472 CLQIVCDWTDYDERMKKLVS 491
Score = 37.7 bits (86), Expect = 0.032
Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 32/226 (14%)
Query: 237 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRG 296
PD +L +L+ ++ + +AH LAI K +P +A +NL +Y +RG
Sbjct: 52 PDNTGVLLLLSSIHFQCRRLDRSAHF--STLAI------KQNPLLAEAYSNLGNVYKERG 103
Query: 297 KYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 356
+ +EA + AL ++ PD NLA G E Y AL+
Sbjct: 104 QLQEAIEHYRHALRLK--------PDFIDGYINLAAALVAAGDMEGAVQAYVSALQY--- 152
Query: 357 RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLY-KEILTRAH----EKEFGSVNGDNKPI 411
+P++ +++L + G+ ++A+ Y K I T+ + G V I
Sbjct: 153 -----NPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 207
Query: 412 WM--HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSL 455
W+ H E+ + D A Y G+ K ++ V LR+L
Sbjct: 208 WLAIHHFEKAVTLDPNFLDA-YINLGNVLKEARIFDRAVAAYLRAL 252
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 49.7 bits (117), Expect = 8e-06
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 23/155 (14%)
Query: 246 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 305
L V + Q+K EA +AL R +A L NL +L + ++ EA
Sbjct: 499 LGNVLKSQSKISEAESAYRNALYYRSN--------MADMLYNLGLLLQENSRFAEALHYY 550
Query: 306 KRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNV 365
K A+ R P +A N ++ NQG+ EE + + EI L DP+
Sbjct: 551 KLAIGSR--------PTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENL--KDPHA 600
Query: 366 AKTK-----NNLASCYLKQGKYQDAETLYKEILTR 395
K+ NL Y +QG Y++A ++YKE + +
Sbjct: 601 HKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Score = 40.4 bits (93), Expect = 0.005
Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 201 LHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAA 260
L+NL Y QG YE A+ + K+A++ + + ++ N++ Y +K EA
Sbjct: 609 LYNLGKLYHEQGHYEEALSVYKEAIQKMPRQFAPQ-----SLYNMMGEAYMRLSKLPEAE 663
Query: 261 HLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 311
H ++L R KT DH T L L G++ EAE L +A+E+
Sbjct: 664 HWYMESL--RSKT---DHIPAHLTYGKLLALTGRK---SEAEKLFLKAIEL 706
Score = 30.4 bits (67), Expect = 5.1
Identities = 43/186 (23%), Positives = 68/186 (36%), Gaps = 27/186 (14%)
Query: 288 LAVLYG-----KRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEE 342
L V YG + G ++ E L + +++ AK NL + ++Q K E
Sbjct: 462 LIVFYGLKTAIRNGDWQNEEMLYRSGIKVNP----------AKAWGNLGNVLKSQSKISE 511
Query: 343 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 402
E YR AL + N+A NL + ++ +A YK L
Sbjct: 512 AESAYRNALYYRS--------NMADMLYNLGLLLQENSRFAEALHYYK--LAIGSRPTLA 561
Query: 403 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 462
S + I M+ EE++ + + K +V + L +LG LY Q
Sbjct: 562 SAYLNTGIILMNQGRTEEARRTFLKCSEIPDEN--LKDPHAHKSSVTSCLYNLGKLYHEQ 619
Query: 463 GKLEAA 468
G E A
Sbjct: 620 GHYEEA 625
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 46.2 bits (108), Expect = 9e-05
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 33/189 (17%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P + + N Y +G Y LC++A+E + + + D+ +A + Y +
Sbjct: 256 PTNMTYITNQAAVYFEKGDYNKCRELCEKAIE-VGRENREDYRQIAKAYARIGNSYFKEE 314
Query: 255 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
KYK+A H N +LA P V K ++AE + K ++
Sbjct: 315 KYKDAIHFYNKSLAEHRT------PDVLK-------------KCQQAEKILK-----EQE 350
Query: 315 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 374
L +PD+A + N C +G + +Y A++ +P AK +N A+
Sbjct: 351 RLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIK--------RNPKDAKLYSNRAA 402
Query: 375 CYLKQGKYQ 383
CY K ++Q
Sbjct: 403 CYTKLLEFQ 411
Score = 37.4 bits (85), Expect = 0.042
Identities = 34/170 (20%), Positives = 66/170 (38%), Gaps = 39/170 (22%)
Query: 264 NDALAIREKTLGKD--------------------HPAVAATLNNLAVLYGKRGKYKEAEP 303
N A++EK LG D P + N A +Y ++G Y +
Sbjct: 221 NKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRE 280
Query: 304 LCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT------- 356
LC++A+E+ + + +AK + + + K ++ ++Y ++L + T
Sbjct: 281 LCEKAIEVGRENREDYR-QIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKC 339
Query: 357 -----------RLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 395
RL +P++A + N + ++G Y A Y E + R
Sbjct: 340 QQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKR 389
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 24/171 (14%)
Query: 236 HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 295
HP L L + + Q K +EA LL D++ K P A ++LA L ++
Sbjct: 436 HPQHNRALFNLGNLLKSQEKKEEAITLLKDSI--------KYGPEFADAYSSLASLLAEQ 487
Query: 296 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 355
++KEAE + + + K PD + +N + + G E+ +Y++A+++
Sbjct: 488 ERFKEAEEIYQTGI--------KNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL-- 537
Query: 356 TRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNG 406
P+ NL Y G+ AE YK L AH+ E S G
Sbjct: 538 ------SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLG 582
Score = 44.7 bits (104), Expect = 3e-04
Identities = 46/197 (23%), Positives = 83/197 (42%), Gaps = 33/197 (16%)
Query: 195 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQN 254
P R L NL SQ + E A+ L K +++ P+ A + LA + +Q
Sbjct: 437 PQHNRALFNLGNLLKSQEKKEEAITLLKDSIKY--------GPEFADAYSSLASLLAEQE 488
Query: 255 KYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 314
++KEA + + K+ P + NN V G ++A ++A+
Sbjct: 489 RFKEAEEIYQTGI--------KNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAI----- 535
Query: 315 VLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLAS 374
K P + NL L ++ G+ E +Y+RAL++ + A+ + L +
Sbjct: 536 ---KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV---------AHKAEILSPLGA 583
Query: 375 CYLKQGKYQDAETLYKE 391
Y G+Y++A +Y+E
Sbjct: 584 LYYNTGRYEEALQIYQE 600
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 27/140 (19%)
Query: 251 RDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE 310
+DQ + KEA + AL + +P A+ LNNL L EA+ +RAL+
Sbjct: 386 KDQGRNKEAIYHYRTALKL--------YPRHASALNNLGTLTRDTA---EAKMYYQRALQ 434
Query: 311 IREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370
+ HP + L NL L ++Q K EE + +++ P A +
Sbjct: 435 L--------HPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKY--------GPEFADAYS 478
Query: 371 NLASCYLKQGKYQDAETLYK 390
+LAS +Q ++++AE +Y+
Sbjct: 479 SLASLLAEQERFKEAEEIYQ 498
Score = 35.0 bits (79), Expect = 0.21
Identities = 43/207 (20%), Positives = 80/207 (38%), Gaps = 46/207 (22%)
Query: 193 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQAL-----------------------EDLE 229
++ + L L Y + GRYE A+ + ++A ++ E
Sbjct: 570 QVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAE 629
Query: 230 KTSGH---DHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLN 286
K + H + +L+ +Y Q + +A ++ AL ++ K P V
Sbjct: 630 KMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKD-----PKV----- 679
Query: 287 NLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYY 346
++ L+ +G + L +A E +V + +PD A+ N+ + +GK Y
Sbjct: 680 -ISELFFTKGNQLREQNLLDKAFE-SYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAY 737
Query: 347 YRRALEIYATRLGPDDPNVAKTKNNLA 373
Y RAL++ P+ K NLA
Sbjct: 738 YERALQLV--------PDSKLLKENLA 756
Score = 34.3 bits (77), Expect = 0.35
Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 14/121 (11%)
Query: 321 PDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQG 380
P AK N A ++QG+ +E Y+YR AL++Y P A NNL +
Sbjct: 372 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLY--------PRHASALNNLGTLTRDTA 423
Query: 381 KYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYG-EYGSWYK 439
+A+ Y+ L + N N + E++EE+ +DS YG E+ Y
Sbjct: 424 ---EAKMYYQRALQLHPQHNRALFNLGN--LLKSQEKKEEAITLLKDSIKYGPEFADAYS 478
Query: 440 A 440
+
Sbjct: 479 S 479
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/298 (21%), Positives = 112/298 (37%), Gaps = 54/298 (18%)
Query: 183 GDVSGQHGGYEIPARLRTLHNLVIQ----YASQGR--------------YEVAVPLCKQA 224
G + G Y+ +L H + Q YA+QGR Y+ AV +Q
Sbjct: 481 GIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQE 540
Query: 225 LEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAAT 284
L+ + + D A+ LA+ Y+ + A + L I + +D + A
Sbjct: 541 LQISMEVN--DRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIAREL--RDIQSEARA 596
Query: 285 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVE 344
L+NL + RG+Y +A P ++ L + PD+ + + +C N G A
Sbjct: 597 LSNLGNFHCSRGEYVQAAPYYEQYLRLA--------PDL-QDMEGEGKVCHNLGYAHYCL 647
Query: 345 YYYRRALEIYATRLG-----PDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE- 398
Y+ A++ Y L D + AK NL + + AE K +L+ A
Sbjct: 648 GNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSL 707
Query: 399 -------KEFGS----------VNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYK 439
+ G+ +NG K + KD+R +++ Y G+ Y+
Sbjct: 708 NNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYR 765
Score = 40.8 bits (94), Expect = 0.004
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 7/153 (4%)
Query: 246 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 305
L YR KY +A L + ++ D P +LA +Y GKY A
Sbjct: 760 LGTAYRMIQKYDKALGYHTQELEVYQEL--SDLPGECRAHGHLAAVYMALGKYTMAFKCY 817
Query: 306 KRALEIREKVLGKFHPDVAKQL-SNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDP- 363
+ L++ +K+ P + Q+ N+ + N EE Y+ + L + G +
Sbjct: 818 EEQLDLGQKLKD---PSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVL 874
Query: 364 NVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 396
+ + NL CY G Y++A Y++ L+ A
Sbjct: 875 DRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVA 907
Score = 33.5 bits (75), Expect = 0.60
Identities = 48/207 (23%), Positives = 80/207 (38%), Gaps = 32/207 (15%)
Query: 199 RTLHNLVIQYASQGRYEVAVPLCKQAL---EDLEKTSGHDHPDVATMLNILALVYRDQNK 255
+ HNL + G Y+ AV +Q L +DL HD A L L ++
Sbjct: 635 KVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDL-----HDKLSQAKAYCNLGLAFKALLN 689
Query: 256 YKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKR----ALEI 311
+ +A L++ + + A L NL ++ +CK+ A++
Sbjct: 690 FSKAEECQKYLLSLAQSL--NNSQAKFRALGNLGDIF-----------ICKKDINGAIKF 736
Query: 312 REKVLGKFHPDVAKQLSNLALLCQNQG-----KAEEVEYYYRRALEIYATRLGPDDPNVA 366
E+ LG H ++L A K ++ Y+ + LE+Y D P
Sbjct: 737 YEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQEL--SDLPGEC 794
Query: 367 KTKNNLASCYLKQGKYQDAETLYKEIL 393
+ +LA+ Y+ GKY A Y+E L
Sbjct: 795 RAHGHLAAVYMALGKYTMAFKCYEEQL 821
Score = 32.7 bits (73), Expect = 1.0
Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 9/141 (6%)
Query: 263 LNDALAIREKTLG-----KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLG 317
L A E+ LG KD A +NL +++ +G Y A L K L I +++
Sbjct: 450 LERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQEL-- 507
Query: 318 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYL 377
+ + N+ G ++ Y+R+ L+I + D + A T NLA Y
Sbjct: 508 SDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQI--SMEVNDRASQASTHGNLAVAYQ 565
Query: 378 KQGKYQDAETLYKEILTRAHE 398
G + A Y+ L A E
Sbjct: 566 ALGAHDRALQHYQNHLNIARE 586
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 29 ETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELG-LGEAQVILALSSHLGA 87
ETL E +AL L EAE Q+RC +L+ +A G L E + + L + A
Sbjct: 307 ETLEEERQALTLRL------EAE---QQRCCVLQEERDAARAGQLSEHRELETLRA---A 354
Query: 88 VESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH--LLFMSQIRK 145
+E E+Q Q +L + Q L+EE ++ + Q AQ E QH L S++R+
Sbjct: 355 LEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRR 414
Query: 146 LDEDASPNEEKGD 158
L+ + + D
Sbjct: 415 LEGELDTARRERD 427
Score = 29.6 bits (65), Expect = 8.7
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 74 EAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQ-----QKLQRSEQAVA 128
EAQ L V+SE ++L ++ +E L+ E++ Q Q++Q +
Sbjct: 394 EAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAV 453
Query: 129 QLEEEKQHLLFMSQIRKLDEDASPNE 154
QLE+ L +Q L + AS E
Sbjct: 454 QLEQRVTERLAQAQESSLRQAASLRE 479
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 29 ETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELG-LGEAQVILALSSHLGA 87
ETL E +AL L EAE Q+RC +L+ +A G L E + + L + A
Sbjct: 307 ETLEEERQALTLRL------EAE---QQRCCVLQEERDAARAGQLSEHRELETLRA---A 354
Query: 88 VESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQH--LLFMSQIRK 145
+E E+Q Q +L + Q L+EE ++ + Q AQ E QH L S++R+
Sbjct: 355 LEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRR 414
Query: 146 LDEDASPNEEKGD 158
L+ + + D
Sbjct: 415 LEGELDTARRERD 427
Score = 29.6 bits (65), Expect = 8.7
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 74 EAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQ-----QKLQRSEQAVA 128
EAQ L V+SE ++L ++ +E L+ E++ Q Q++Q +
Sbjct: 394 EAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAV 453
Query: 129 QLEEEKQHLLFMSQIRKLDEDASPNE 154
QLE+ L +Q L + AS E
Sbjct: 454 QLEQRVTERLAQAQESSLRQAASLRE 479
>gi|116089276 tetratricopeptide repeat domain 23-like [Homo sapiens]
Length = 361
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 10/136 (7%)
Query: 259 AAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGK-------RGKYKEAEPLCKRALEI 311
A H LN ALA EK +G A ++L LY + R + +A ++A +
Sbjct: 225 AIHRLNLALAYFEKAIGDVIAAKGDRTSDLISLYEEAAQIEQLRRNHNQAIQYLQQAHSV 284
Query: 312 REKVLGKFHPDVAKQLSNLALLCQNQGKAEE---VEYYYRRALEIYATRLGPDDPNVAKT 368
+ + P A+ + LA G+A+ VE Y+ R++ Y LG +D T
Sbjct: 285 CVSLFTEVSPKTAEMSALLAKAYAMSGEAQHRDAVEIYFIRSINAYRATLGSEDFETLST 344
Query: 369 KNNLASCYLKQGKYQD 384
++ G+ QD
Sbjct: 345 TEEFCKWLVQNGEKQD 360
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 40.0 bits (92), Expect = 0.006
Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 5/125 (4%)
Query: 31 LRGEHRALLAPLV---APEAGEAEPGSQERCILLRRSLEAIELGLGEAQVILALSSHLGA 87
L+ + RA L LV AP E QE L RR E + + + L
Sbjct: 437 LKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQ 496
Query: 88 VESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLD 147
+ EK+ L +VR L ++ Q+L +LA Q + E+ QL ++K HL Q+ L+
Sbjct: 497 QQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHL--SQQVGMLE 554
Query: 148 EDASP 152
A P
Sbjct: 555 RLAGP 559
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.7 bits (91), Expect = 0.008
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 89 ESEKQKLRAQVRRLVQEN--QWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKL 146
E E+ +L Q +RL QE Q+ EE TQ+K +R EQ + Q EE+K+ + RKL
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRR---QERERKL 1880
Query: 147 DEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGDV--SGQHGGYEIPARLRTLHNL 204
E+ ++K + + ++ E + G G + G H +P R L+
Sbjct: 1881 REEHIRRQQKEEQRHRQVGEIKSQEGK-------GHGRLLEPGTHQFASVPVRSSPLYEY 1933
Query: 205 VIQYASQGR 213
+ + SQ R
Sbjct: 1934 IQEQRSQYR 1942
Score = 33.9 bits (76), Expect = 0.46
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Query: 51 EPGSQERCILLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLR 110
EP + R R+ E EL E Q++ E E+Q R + +E Q LR
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ-YREEEEVQQEEEQLLR 1155
Query: 111 EELAGTQ-QKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFP 169
EE + Q+L+R + +L++E++ LL Q ++ E E+ ++ + +
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 170 NEDEQS 175
+ED++S
Sbjct: 1216 DEDQRS 1221
Score = 33.9 bits (76), Expect = 0.46
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 16/101 (15%)
Query: 89 ESEKQKLRAQ------------VRRLVQENQWLREELAGTQQKLQRSEQAVAQL--EEEK 134
E E+Q+LR Q +RR +E ++L+EE +Q+L+R + QL E E+
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 135 QHLLFMSQIRKL--DEDASPNEEKGDVPKDTLDDLFPNEDE 173
+ L + RK+ +E P E+ + + D F E++
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 89 ESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDE 148
E +Q+LR + ++ +EE QQ+L+ +Q + EE ++ LL + ++L++
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 149 DASPNEEKGDVPKDTLDDLFPNEDEQ 174
+ K + ++ D L E+E+
Sbjct: 561 ERREQRLKRE-QEERRDQLLKREEER 585
Score = 29.6 bits (65), Expect = 8.7
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 9/76 (11%)
Query: 88 VESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEE-------EKQHLLFM 140
++ E+Q R ++ R +E + LR+E Q++L+R E+ LEE E+Q L
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQET--EQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767
Query: 141 SQIRKLDEDASPNEEK 156
+ RK E+ +E+
Sbjct: 1768 ERDRKFREEEQLRQER 1783
>gi|55749678 ninein-like [Homo sapiens]
Length = 1382
Score = 39.3 bits (90), Expect = 0.011
Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Query: 8 REEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEA 67
RE ++ ++ K ++ ++ + H + L L + E G +ER LLR +EA
Sbjct: 398 RERDKARQDLERAEKRNLEFVKEMDDCH-STLEQLTEKKIKHLEQGYRERLSLLRSEVEA 456
Query: 68 I-ELGLGEA-QVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQ 125
EL +A + AL +G +++E+ LR ++ ++EN L++E+ +KL SE+
Sbjct: 457 ERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSER 516
Query: 126 AVAQLEEEKQHLL 138
+L+++ + +L
Sbjct: 517 LALKLQKDLEFVL 529
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 38.9 bits (89), Expect = 0.014
Identities = 36/102 (35%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 29 ETLRGEHRALLAPLVAPEAGEAEPGSQERCILLRRSLEAIELGLGEAQVILA-LSSHLGA 87
E L EH L LVA E E S+E LR EA+E L E Q LA L +
Sbjct: 872 EALAKEHAGLAVQLVAAER-EGRTLSEE-ATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929
Query: 88 VESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQ 129
+E+E Q L L E LR+++ TQ+K ++ +AQ
Sbjct: 930 LEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQ 971
Score = 35.0 bits (79), Expect = 0.21
Identities = 130/575 (22%), Positives = 202/575 (35%), Gaps = 89/575 (15%)
Query: 8 REEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLVAPEA---GEAEPGSQERCILLRRS 64
R E+ S + + A+ + L + + L+A L ++ G QE +
Sbjct: 728 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 787
Query: 65 LEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSE 124
EL L + L L E ++ L Q+ L E L+E+LA ++L E
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Query: 125 QAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDTLDDLFPNEDEQSPAPSPGGGD 184
Q + Q E Q Q+ L+ A E L E E G
Sbjct: 848 QELEQARREAQR-----QVEALERAAREKEALAKEHAGLAVQLVAAERE--------GRT 894
Query: 185 VSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCK-QALEDLEKTSGHDHPDVATML 243
+S E RLR L + +EV L + +A + + G
Sbjct: 895 LS------EEATRLR----LEKEALEGSLFEVQRQLAQLEARREQLEAEGQ--------- 935
Query: 244 NILALVYRDQNKYKEAAHLLNDALAIREK-TLGKDHPA---VAATLNNLAVLYGKRGKYK 299
AL+ + E A L +A +EK +L K+ A V A A L +R ++
Sbjct: 936 ---ALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHE 992
Query: 300 EAEPLCKRALEIREKVLGKFHPDVAKQLSNLA--LLCQNQGKAEEVEYYYRRALEIYATR 357
E +R E + L + QL LL + + + EE+ EI A +
Sbjct: 993 EDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSE------EIAALQ 1046
Query: 358 LGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEE 417
D+ L + + Q A +L + T EK G+ + I + E
Sbjct: 1047 QERDE-----------GLLLAESEKQQALSLKESEKTALSEKLMGTRHS-LATISLEMER 1094
Query: 418 REESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASR 477
++ R++ D TVN L L ++ + AAH E R
Sbjct: 1095 QKRDAQSRQEQ---------------DRSTVNALTSELRDLRAQREEAAAAHAQE--VRR 1137
Query: 478 NRKQGLDPASQTKVVELLKDGSGRRGDRRSSRDMAGGAGPR---SESDLEDVGPTAEWNG 534
++Q D Q L++ R R D G ++ L + E
Sbjct: 1138 LQEQARDLGKQRD--SCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 1195
Query: 535 DGSGSLRRS-GSFGKLRDALRRSSEML---VKKLQ 565
+G LRRS G K R+ALRRS+E L VKK +
Sbjct: 1196 QEAGELRRSLGEGAKEREALRRSNEELRSAVKKAE 1230
Score = 34.7 bits (78), Expect = 0.27
Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 14/168 (8%)
Query: 9 EEKLSQDEIVLGTKAVIQGLE-TLR---GEHRALLAPLVAPEAGEAEPGSQERCILLRRS 64
+ + +DE+ + AV + LE LR GE + ++ E QE RR
Sbjct: 99 QSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRK 158
Query: 65 LEAIELGLG-EAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRS 123
L+A + G +AQ++ L G + K++ ++L++ + L ++ + Q
Sbjct: 159 LQAYQEGQQRQAQLVQRLQ---GKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDL 215
Query: 124 EQAVAQLEEEKQHLLFMSQI-----RKLDEDASPNEE-KGDVPKDTLD 165
E A+ +LEEE+Q ++Q+ +LD+ S N+ D+ K T D
Sbjct: 216 ESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTND 263
Score = 33.5 bits (75), Expect = 0.60
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 89 ESEKQKLRAQVRRLVQENQWLREELAGTQQKL---QRSEQAVAQLEEEKQHLLFMSQIRK 145
E E Q+ R VR+ V+ + L+EE A ++KL Q +Q AQL + Q + + R
Sbjct: 128 ELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRC 187
Query: 146 LDEDASPNEEKGDVPKDTLDDLFPNEDEQS 175
+ + E G++ + L D ++D +S
Sbjct: 188 SELEQQLLERSGELEQQRLRDTEHSQDLES 217
Score = 30.4 bits (67), Expect = 5.1
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 81 LSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFM 140
L L ESE++ L Q++RL + + Q+++QR A L EK +L
Sbjct: 552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611
Query: 141 SQI-RKLDEDASPNEEKGDVPKDTL----DDLFPNEDEQSPAPSPG 181
Q+ ++ E+ EK ++ L D L E+EQ A G
Sbjct: 612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRL---EEEQEDAVQDG 654
Score = 29.6 bits (65), Expect = 8.7
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 50 AEPGSQERCILLRRSLEAIELGLGEAQVIL--ALSSHLGAVESEKQKLRAQVRRLVQENQ 107
A +++ LL + A+ GE + L S L A E Q+LR Q++ L EN
Sbjct: 1239 ANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEA-RRELQELRRQMKMLDSENT 1297
Query: 108 WLREELAGTQQKLQRSEQAVAQLEEE 133
L ELA Q +L E+A + E
Sbjct: 1298 RLGRELAELQGRLALGERAEKESRRE 1323
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 38.5 bits (88), Expect = 0.019
Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 24/123 (19%)
Query: 256 YKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKV 315
++ A H A+ + +PA A N A Y K G Y A C+RA+ I
Sbjct: 107 FEAAVHFYGKAIEL--------NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICI---- 154
Query: 316 LGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASC 375
P +K + L + K E YY++ALE+ DP+ K+NL
Sbjct: 155 ----DPAYSKAYGRMGLALSSLNKHVEAVAYYKKALEL--------DPDNETYKSNLKIA 202
Query: 376 YLK 378
LK
Sbjct: 203 ELK 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,969,231
Number of Sequences: 37866
Number of extensions: 1249517
Number of successful extensions: 6590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 294
Number of HSP's that attempted gapping in prelim test: 5262
Number of HSP's gapped (non-prelim): 1330
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.