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Search of human proteins with 19743840
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 732 0.0
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 689 0.0
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 689 0.0
gi|213417911 protein kinase, interferon-inducible double strande... 265 5e-71
gi|4505581 protein kinase, interferon-inducible double stranded ... 260 1e-69
gi|213417919 protein kinase, interferon-inducible double strande... 258 8e-69
gi|7657625 staufen homolog 2 [Homo sapiens] 79 5e-15
gi|82659089 staufen isoform a [Homo sapiens] 79 8e-15
gi|82659087 staufen isoform b [Homo sapiens] 79 8e-15
gi|82659085 staufen isoform a [Homo sapiens] 79 8e-15
gi|82659083 staufen isoform a [Homo sapiens] 79 8e-15
gi|82659091 staufen isoform c [Homo sapiens] 77 2e-14
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 73 5e-13
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 73 5e-13
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 73 5e-13
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 73 5e-13
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 68 1e-11
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 68 1e-11
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 68 1e-11
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 60 2e-09
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 60 4e-09
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 59 9e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 59 9e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 59 9e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 58 1e-08
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 58 1e-08
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 50 4e-06
gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens] 39 0.007
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 39 0.007
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 35 0.081
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 732 bits (1889), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP 60
MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP
Sbjct: 1 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP 60
Query: 61 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 120
NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE
Sbjct: 61 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 120
Query: 121 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 180
DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV
Sbjct: 121 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 180
Query: 181 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP 240
TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP
Sbjct: 181 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP 240
Query: 241 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE 300
DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE
Sbjct: 241 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE 300
Query: 301 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK 360
LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK
Sbjct: 301 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK 360
Query: 361 IMAGSK 366
IMAGSK
Sbjct: 361 IMAGSK 366
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 689 bits (1779), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 22 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 81
MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK
Sbjct: 1 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 60
Query: 82 AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 141
AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR
Sbjct: 61 AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 120
Query: 142 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 201
SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF
Sbjct: 121 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 180
Query: 202 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 261
IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP
Sbjct: 181 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 240
Query: 262 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 321
GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG
Sbjct: 241 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 300
Query: 322 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 366
LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK
Sbjct: 301 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 345
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 689 bits (1779), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 22 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 81
MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK
Sbjct: 1 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 60
Query: 82 AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 141
AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR
Sbjct: 61 AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 120
Query: 142 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 201
SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF
Sbjct: 121 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 180
Query: 202 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 261
IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP
Sbjct: 181 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 240
Query: 262 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 321
GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG
Sbjct: 241 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 300
Query: 322 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 366
LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK
Sbjct: 301 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 345
>gi|213417911 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 2 [Homo sapiens]
Length = 302
Score = 265 bits (677), Expect = 5e-71
Identities = 151/357 (42%), Positives = 202/357 (56%), Gaps = 57/357 (15%)
Query: 10 TTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG 69
+T CG S+ +M+ A PGKTPI +L EYG + PVY+ +++ Q H P FTFRVTVG
Sbjct: 3 STPFCGFCSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVG 62
Query: 70 DTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAA 129
D +CTG+G SKK AKH+AAE A+ LK + S F+ D +P+
Sbjct: 63 DITCTGEGTSKKLAKHRAAEAAINILKANA--------SICFAVPDPLMPD--------- 105
Query: 130 AATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHR 189
P +++ NP+G+LQEL + GWRLPEYT++QE GPAH+
Sbjct: 106 --------------------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHK 145
Query: 190 KEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGV 249
+E+T CR+E F+E G G SKK AKRNAA K L + + ++H S
Sbjct: 146 REYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNI-----------SPENHIS--- 191
Query: 250 GSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHV 309
L + GCTW SLRNS GEKI L+ L ++LSE+++EQ F++
Sbjct: 192 ---LTNVVGHSLGCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAKEQGFNI 245
Query: 310 SYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 366
+YLDI+ELS +G QCL ELST P TVCHGS + A+ +AA ALQYLKI+A K
Sbjct: 246 TYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 302
>gi|4505581 protein kinase, interferon-inducible double stranded RNA
dependent activator isoform 1 [Homo sapiens]
Length = 313
Score = 260 bits (665), Expect = 1e-69
Identities = 152/363 (41%), Positives = 203/363 (55%), Gaps = 63/363 (17%)
Query: 4 EEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFT 63
E + SGT S+ +M+ A PGKTPI +L EYG + PVY+ +++ Q H P FT
Sbjct: 14 EREDSGTF------SLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFT 67
Query: 64 FRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIP 123
FRVTVGD +CTG+G SKK AKH+AAE A+ LK + S F+ D +P+
Sbjct: 68 FRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANA--------SICFAVPDPLMPD--- 116
Query: 124 VFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQE 183
P +++ NP+G+LQEL + GWRLPEYT++QE
Sbjct: 117 --------------------------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQE 150
Query: 184 SGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDD 243
GPAH++E+T CR+E F+E G G SKK AKRNAA K L + + ++
Sbjct: 151 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNI-----------SPEN 199
Query: 244 HFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSE 303
H S L + GCTW SLRNS GEKI L+ L ++LSE+++
Sbjct: 200 HIS------LTNVVGHSLGCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAK 250
Query: 304 EQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMA 363
EQ F+++YLDI+ELS +G QCL ELST P TVCHGS + A+ +AA ALQYLKI+A
Sbjct: 251 EQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIA 310
Query: 364 GSK 366
K
Sbjct: 311 ERK 313
>gi|213417919 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 3 [Homo sapiens]
Length = 288
Score = 258 bits (658), Expect = 8e-69
Identities = 147/345 (42%), Positives = 195/345 (56%), Gaps = 57/345 (16%)
Query: 22 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKK 81
M+ A PGKTPI +L EYG + PVY+ +++ Q H P FTFRVTVGD +CTG+G SKK
Sbjct: 1 MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKK 60
Query: 82 AAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTR 141
AKH+AAE A+ LK + S F+ D +P+
Sbjct: 61 LAKHRAAEAAINILKANA--------SICFAVPDPLMPD--------------------- 91
Query: 142 SPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERF 201
P +++ NP+G+LQEL + GWRLPEYT++QE GPAH++E+T CR+E F
Sbjct: 92 --------PSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESF 143
Query: 202 IEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGP 261
+E G G SKK AKRNAA K L + + ++H S L +
Sbjct: 144 METGKGASKKQAKRNAAEKFLAKFSNI-----------SPENHIS------LTNVVGHSL 186
Query: 262 GCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSG 321
GCTW SLRNS GEKI L+ L ++LSE+++EQ F+++YLDI+ELS +G
Sbjct: 187 GCTWHSLRNSPGEKINLLKR---SLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANG 243
Query: 322 LCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK 366
QCL ELST P TVCHGS + A+ +AA ALQYLKI+A K
Sbjct: 244 QYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK 288
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 79.3 bits (194), Expect = 5e-15
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 31/198 (15%)
Query: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAA 88
K+ ISL+ E + ++++K G H +F RV+VG+ S G+G SKK +K +AA
Sbjct: 174 KSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAA 233
Query: 89 EVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQ 148
L+ LK LP +PV P + + P ++
Sbjct: 234 TTVLQELK--------------------KLPP-LPVVEK-------PKLFFKKRPKTIVK 265
Query: 149 PPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSG 207
P+ + NP+ L ++ K + P+Y + E G R+EF M +V + G+G
Sbjct: 266 --AGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTG 323
Query: 208 TSKKLAKRNAAAKMLLRV 225
+KK+AK+NAA MLL++
Sbjct: 324 PNKKIAKKNAAEAMLLQL 341
Score = 52.8 bits (125), Expect = 5e-07
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 37/168 (22%)
Query: 62 FTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPED 121
F ++TVG+ G+G +++AA+H AA AL+ L+ + E + ++ S +D +
Sbjct: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMDDDKDAN 173
Query: 122 IPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVT 181
+ + V + L R+ P+ + V
Sbjct: 174 ------KSEISLVFEIALKRNMPVSFE-------------------------------VI 196
Query: 182 QESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
+ESGP H K F V F G G SKKL+K+ AA +L + +P
Sbjct: 197 KESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/82 (40%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ TG GP+KK AK
Sbjct: 273 GMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKN 332
Query: 87 AAEVALKHL--KGGSMLEPALE 106
AAE L L K + L+ LE
Sbjct: 333 AAEAMLLQLGYKASTNLQDQLE 354
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 78.6 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
Query: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
AA L+ LK +P A P + ++ P+
Sbjct: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
Query: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
Query: 205 GSGTSKKLAKRNAAAKML 222
G+GT+KK+AKRNAA ML
Sbjct: 251 GTGTNKKVAKRNAAENML 268
Score = 49.7 bits (117), Expect = 4e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 77 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
Query: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196
+ L R+ P+ + V +ESGP H K F
Sbjct: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
Query: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
V F+ G G SKK++K+NAA +L + +P
Sbjct: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 87 AAEVALKHL 95
AAE L+ L
Sbjct: 263 AAENMLEIL 271
Score = 28.5 bits (62), Expect = 9.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 298 LSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQ 357
L LS Q F V Y D + + + L+ S+QP + HG E+ AA L+
Sbjct: 412 LDYLSRVQGFQVEYKDFPKNNKNEFVS-LINCSSQPPLISHGIGKDVESCHDMAALNILK 470
Query: 358 YL 359
L
Sbjct: 471 LL 472
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 78.6 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 180 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 239
Query: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
AA L+ LK +P A P + ++ P+
Sbjct: 240 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 272
Query: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 273 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 331
Query: 205 GSGTSKKLAKRNAAAKML 222
G+GT+KK+AKRNAA ML
Sbjct: 332 GTGTNKKVAKRNAAENML 349
Score = 52.4 bits (124), Expect = 6e-07
Identities = 57/235 (24%), Positives = 90/235 (38%), Gaps = 64/235 (27%)
Query: 18 SIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLL------------KAEGQAHQPNFTF- 64
SI AA TP L ++GK P+Y + G A+ P + +
Sbjct: 60 SITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYP 119
Query: 65 ----------RVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPL 114
++VG G+G +++AAKH AA AL+ L+ + E LE + S
Sbjct: 120 FPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEE 178
Query: 115 DSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWR 174
++ +I + V + L R+ P+ +
Sbjct: 179 ENLNKSEI---------SQVFEIALKRNLPVNFE-------------------------- 203
Query: 175 LPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
V +ESGP H K F V F+ G G SKK++K+NAA +L + +P
Sbjct: 204 -----VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 343
Query: 87 AAEVALKHL 95
AAE L+ L
Sbjct: 344 AAENMLEIL 352
Score = 28.5 bits (62), Expect = 9.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 298 LSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQ 357
L LS Q F V Y D + + + L+ S+QP + HG E+ AA L+
Sbjct: 493 LDYLSRVQGFQVEYKDFPKNNKNEFVS-LINCSSQPPLISHGIGKDVESCHDMAALNILK 551
Query: 358 YL 359
L
Sbjct: 552 LL 553
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 78.6 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
Query: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
AA L+ LK +P A P + ++ P+
Sbjct: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
Query: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
Query: 205 GSGTSKKLAKRNAAAKML 222
G+GT+KK+AKRNAA ML
Sbjct: 251 GTGTNKKVAKRNAAENML 268
Score = 49.7 bits (117), Expect = 4e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 77 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
Query: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196
+ L R+ P+ + V +ESGP H K F
Sbjct: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
Query: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
V F+ G G SKK++K+NAA +L + +P
Sbjct: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 87 AAEVALKHL 95
AAE L+ L
Sbjct: 263 AAENMLEIL 271
Score = 28.5 bits (62), Expect = 9.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 298 LSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQ 357
L LS Q F V Y D + + + L+ S+QP + HG E+ AA L+
Sbjct: 412 LDYLSRVQGFQVEYKDFPKNNKNEFVS-LINCSSQPPLISHGIGKDVESCHDMAALNILK 470
Query: 358 YL 359
L
Sbjct: 471 LL 472
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 78.6 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 99 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 158
Query: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
AA L+ LK +P A P + ++ P+
Sbjct: 159 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 191
Query: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 192 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 250
Query: 205 GSGTSKKLAKRNAAAKML 222
G+GT+KK+AKRNAA ML
Sbjct: 251 GTGTNKKVAKRNAAENML 268
Score = 49.7 bits (117), Expect = 4e-06
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 55/213 (25%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 77 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
Query: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196
+ L R+ P+ + V +ESGP H K F
Sbjct: 111 IALKRNLPVNFE-------------------------------VARESGPPHMKNFVTKV 139
Query: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
V F+ G G SKK++K+NAA +L + +P
Sbjct: 140 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 203 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 262
Query: 87 AAEVALKHL 95
AAE L+ L
Sbjct: 263 AAENMLEIL 271
Score = 28.5 bits (62), Expect = 9.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 298 LSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQ 357
L LS Q F V Y D + + + L+ S+QP + HG E+ AA L+
Sbjct: 412 LDYLSRVQGFQVEYKDFPKNNKNEFVS-LINCSSQPPLISHGIGKDVESCHDMAALNILK 470
Query: 358 YL 359
L
Sbjct: 471 LL 472
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 77.0 bits (188), Expect = 2e-14
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 29/192 (15%)
Query: 32 ISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVA 91
I+L + P+ + + G H NF +V+VG+ G+G SKK +K AA
Sbjct: 111 IALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAV 170
Query: 92 LKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPV 151
L+ LK +P A P + ++ P+ ++P
Sbjct: 171 LEELK------------------------KLPPLPAVERVKPR---IKKKTKPI-VKPQT 202
Query: 152 SPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSK 210
SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V G+GT+K
Sbjct: 203 SPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNK 262
Query: 211 KLAKRNAAAKML 222
K+AKRNAA ML
Sbjct: 263 KVAKRNAAENML 274
Score = 52.0 bits (123), Expect = 8e-07
Identities = 53/213 (24%), Positives = 88/213 (41%), Gaps = 49/213 (23%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTF-----------RVTVGDTSCTGQ 76
GK P+ + +R+ T Y++ G A+ P + + ++VG G+
Sbjct: 4 GKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 77 GPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPS 136
G +++AAKH AA AL+ L+ + E LE + S ++ +I + V
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKSEI---------SQVFE 110
Query: 137 VVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTC 196
+ L R+ P+ + P V +ESGP H K F
Sbjct: 111 IALKRNLPVNFES-------------------------FPLKQVARESGPPHMKNFVTKV 145
Query: 197 RVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
V F+ G G SKK++K+NAA +L + +P
Sbjct: 146 SVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 209 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 268
Query: 87 AAEVALKHL 95
AAE L+ L
Sbjct: 269 AAENMLEIL 277
Score = 28.5 bits (62), Expect = 9.9
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 298 LSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQ 357
L LS Q F V Y D + + + L+ S+QP + HG E+ AA L+
Sbjct: 418 LDYLSRVQGFQVEYKDFPKNNKNEFVS-LINCSSQPPLISHGIGKDVESCHDMAALNILK 476
Query: 358 YL 359
L
Sbjct: 477 LL 478
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 72.8 bits (177), Expect = 5e-13
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Query: 97 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 135
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
Query: 136 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 195
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
Query: 196 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 242
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 72.8 bits (177), Expect = 5e-13
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Query: 97 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 135
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
Query: 136 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 195
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
Query: 196 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 242
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 72.8 bits (177), Expect = 5e-13
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Query: 97 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 135
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
Query: 136 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 195
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
Query: 196 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 242
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 72.8 bits (177), Expect = 5e-13
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Query: 97 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 135
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
Query: 136 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 195
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
Query: 196 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 242
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 317 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 376
Query: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 377 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 425
Query: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 426 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
Query: 200 RFIEIGSGTSKKLAKRNAA 218
R+ SKK K+ AA
Sbjct: 472 RWFPAVCAHSKKQGKQEAA 490
Score = 56.2 bits (134), Expect = 4e-08
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
Query: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
A A+ L LE A S S S + A + TP PS S
Sbjct: 267 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 318
Query: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 319 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 365
Query: 206 SGTSKKLAKRNAAAKMLLRVH 226
S SKK+AK+ AA + + +H
Sbjct: 366 SAPSKKVAKQMAAEEAMKALH 386
Score = 36.2 bits (82), Expect = 0.048
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 432 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 491
Query: 90 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 149
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 492 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 535
Query: 150 PVSP 153
P
Sbjct: 536 KTLP 539
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
Query: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
Query: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 200 RFIEIGSGTSKKLAKRNAA 218
R+ SKK K+ AA
Sbjct: 767 RWFPAVCAHSKKQGKQEAA 785
Score = 56.2 bits (134), Expect = 4e-08
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
A A+ L LE A S S S + A + TP PS S
Sbjct: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
Query: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
Query: 206 SGTSKKLAKRNAAAKMLLRVH 226
S SKK+AK+ AA + + +H
Sbjct: 661 SAPSKKVAKQMAAEEAMKALH 681
Score = 35.0 bits (79), Expect = 0.11
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
Query: 90 VALKHLKG 97
AL+ L G
Sbjct: 787 AALRVLIG 794
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
Query: 87 AAEVALKHLKGGSMLEPALED------SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLT 140
AAE A+K L G + A ++ S S L+S +P + + +V
Sbjct: 672 AAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKV---------RKIGELV-- 720
Query: 141 RSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-E 199
+ NPVG L E G+ E+ + +SGP H +F +V
Sbjct: 721 -------------RYLNTNPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 200 RFIEIGSGTSKKLAKRNAA 218
R+ SKK K+ AA
Sbjct: 767 RWFPAVCAHSKKQGKQEAA 785
Score = 56.2 bits (134), Expect = 4e-08
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
A A+ L LE A S S S + A + TP PS S
Sbjct: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
Query: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
Query: 206 SGTSKKLAKRNAAAKMLLRVH 226
S SKK+AK+ AA + + +H
Sbjct: 661 SAPSKKVAKQMAAEEAMKALH 681
Score = 36.2 bits (82), Expect = 0.048
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 17/124 (13%)
Query: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 727 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 786
Query: 90 VALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQP 149
AL+ L G E + F+ E PV A+ T ++L+RSP E QP
Sbjct: 787 AALRVLIG----ENEKAERMGFT-------EVTPVTGASLRRT---MLLLSRSP--EAQP 830
Query: 150 PVSP 153
P
Sbjct: 831 KTLP 834
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 60.5 bits (145), Expect = 2e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 9/217 (4%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y LL G H P FT V V T+ GPSKK AK A L+ + + + +E
Sbjct: 404 YKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIEC 463
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQEL 167
SS D+ + V + ++ T + + + + Q P+ + NPV L E
Sbjct: 464 MSSDEKSDNESKNE-TVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGK-NPVMELNE- 520
Query: 168 VVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHT 227
++G + Y + E+G +H K F M V+ G+G +KK+AK +AA L ++ +
Sbjct: 521 -KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFS 576
Query: 228 VPLDARDGNE--VEPDDDHFSIGVGSRLDGLRNRGPG 262
P A + + + + V + + +R RG G
Sbjct: 577 GPNAANNKKKKIIPQAKGVVNTAVSAAVQAVRGRGRG 613
Score = 40.0 bits (92), Expect = 0.003
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKA 87
GK P+ L E + Y+L+ G +H F V V G GP+KK AK A
Sbjct: 511 GKNPVMELNEKRRGLK----YELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASA 566
Query: 88 AEVALKHLKGG 98
A AL+ L G
Sbjct: 567 ALAALEKLFSG 577
Score = 37.4 bits (85), Expect = 0.021
Identities = 19/46 (41%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + +SGP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 403 QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVL 448
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 59.7 bits (143), Expect = 4e-09
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 40/193 (20%)
Query: 28 GKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVG-DTSCTGQGPSKKAAKHK 86
GK+P++ L E ++G + + LL EG AH+P F + V VG T + PSKK AK
Sbjct: 612 GKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQM 671
Query: 87 AAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPME 146
AAE A+K L G + +S+ D V
Sbjct: 672 AAEEAMKALHGEA---------------TNSMASDNQVRKIGELV--------------- 701
Query: 147 LQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV-ERFIEIG 205
+ NPVG L E G+ E+ + +SGP H +F +V R+
Sbjct: 702 -------RYLNTNPVGGLLEYARSHGF-AAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAV 753
Query: 206 SGTSKKLAKRNAA 218
SKK K+ AA
Sbjct: 754 CAHSKKQGKQEAA 766
Score = 56.2 bits (134), Expect = 4e-08
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 24/201 (11%)
Query: 29 KTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKA 87
K PIS L EY +T +++++ G H+P F F+V + G + SKK AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 88 AEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL 147
A A+ L LE A S S S + A + TP PS S
Sbjct: 562 AMKAMTIL-----LEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGK--- 613
Query: 148 QPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRV--ERFIEIG 205
+PV L E + + G E+ + + GPAH +F V + F +
Sbjct: 614 -----------SPVTTLLECMHKLG-NSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSV- 660
Query: 206 SGTSKKLAKRNAAAKMLLRVH 226
S SKK+AK+ AA + + +H
Sbjct: 661 SAPSKKVAKQMAAEEAMKALH 681
Score = 35.0 bits (79), Expect = 0.11
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 31 PISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQ-GPSKKAAKHKAAE 89
P+ L EY G + L+ G H+P F ++ VG SKK K +AA+
Sbjct: 708 PVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAAD 767
Query: 90 VALKHLKG 97
AL+ L G
Sbjct: 768 AALRVLIG 775
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 58.5 bits (140), Expect = 9e-09
Identities = 60/195 (30%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y L+ G H P FT V V S GPSKK AK A L+ + L E
Sbjct: 418 YKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMG----LPTGAEG 473
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL-----QPPVSPQQSECNPVG 162
S DS+ E+ A A PV V T S Q P+ + + NPV
Sbjct: 474 RDSSKGEDSA--EETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGK-NPVM 530
Query: 163 ALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
L E ++G + Y + E+G +H K F M V+ G+G++KK+AK AA L
Sbjct: 531 ELNE--KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 223 LRVHTVPLDARDGNE 237
++ A D N+
Sbjct: 586 EKLFPDTPLALDANK 600
Score = 35.8 bits (81), Expect = 0.062
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + ++GP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVL 462
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 58.5 bits (140), Expect = 9e-09
Identities = 60/195 (30%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y L+ G H P FT V V S GPSKK AK A L+ + L E
Sbjct: 418 YKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMG----LPTGAEG 473
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL-----QPPVSPQQSECNPVG 162
S DS+ E+ A A PV V T S Q P+ + + NPV
Sbjct: 474 RDSSKGEDSA--EETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGK-NPVM 530
Query: 163 ALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
L E ++G + Y + E+G +H K F M V+ G+G++KK+AK AA L
Sbjct: 531 ELNE--KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 223 LRVHTVPLDARDGNE 237
++ A D N+
Sbjct: 586 EKLFPDTPLALDANK 600
Score = 35.8 bits (81), Expect = 0.062
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + ++GP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVL 462
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 58.5 bits (140), Expect = 9e-09
Identities = 60/195 (30%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y L+ G H P FT V V S GPSKK AK A L+ + L E
Sbjct: 418 YKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMG----LPTGAEG 473
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMEL-----QPPVSPQQSECNPVG 162
S DS+ E+ A A PV V T S Q P+ + + NPV
Sbjct: 474 RDSSKGEDSA--EETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGK-NPVM 530
Query: 163 ALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
L E ++G + Y + E+G +H K F M V+ G+G++KK+AK AA L
Sbjct: 531 ELNE--KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 223 LRVHTVPLDARDGNE 237
++ A D N+
Sbjct: 586 EKLFPDTPLALDANK 600
Score = 35.8 bits (81), Expect = 0.062
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + ++GP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVL 462
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 58.2 bits (139), Expect = 1e-08
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y L+ G H P FT V V S GPSKK AK A L+ + L E
Sbjct: 418 YKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMG----LPTGAEG 473
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPP---------MELQPPVSPQQSEC 158
S DS+ E+ A A PV V T S ++ Q P+ + +
Sbjct: 474 RDSSKGEDSA--EETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGK- 530
Query: 159 NPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 218
NPV L E ++G + Y + E+G +H K F M V+ G+G++KK+AK AA
Sbjct: 531 NPVMELNE--KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA 585
Query: 219 AKMLLRVHTVPLDARDGNE 237
L ++ A D N+
Sbjct: 586 LAALEKLFPDTPLALDANK 604
Score = 35.8 bits (81), Expect = 0.062
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + ++GP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVL 462
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 58.2 bits (139), Expect = 1e-08
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALED 107
Y L+ G H P FT V V S GPSKK AK A L+ + L E
Sbjct: 418 YKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMG----LPTGAEG 473
Query: 108 SSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPP---------MELQPPVSPQQSEC 158
S DS+ E+ A A PV V T S ++ Q P+ + +
Sbjct: 474 RDSSKGEDSA--EETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGK- 530
Query: 159 NPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 218
NPV L E ++G + Y + E+G +H K F M V+ G+G++KK+AK AA
Sbjct: 531 NPVMELNE--KRRGLK---YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAA 585
Query: 219 AKMLLRVHTVPLDARDGNE 237
L ++ A D N+
Sbjct: 586 LAALEKLFPDTPLALDANK 604
Score = 35.8 bits (81), Expect = 0.062
Identities = 18/46 (39%), Positives = 26/46 (56%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
+Y + ++GP H FTM+ V+ SG SKK AK + A K+L
Sbjct: 417 QYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVL 462
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 49.7 bits (117), Expect = 4e-06
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Y + G H P F V V + G GP+KK AK +AAE+AL+ HL
Sbjct: 142 YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLA 201
Query: 97 GGSMLEPALEDSSSFSPLDSSLPEDI-------------PVFTAAAAATPVPSVVLTRSP 143
G P + +S + +L ++ P A +A +L R+
Sbjct: 202 MGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRAL 261
Query: 144 PMELQPPVSP-QQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFI 202
+ P +P E NPV L L + G R Y E + F M V+
Sbjct: 262 DLVGPTPATPAAPGERNPVVLLNRL--RAGLR---YVCLAEPAERRARSFVMAVSVDGRT 316
Query: 203 EIGSGTSKKLAKRNAAAKMLLRVHTVPL 230
GSG SKKLA+ AA L + + +
Sbjct: 317 FEGSGRSKKLARGQAAQAALQELFDIQM 344
Score = 30.0 bits (66), Expect = 3.4
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 218
+Y ++GP H F + V G+G +KK AK AA
Sbjct: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAA 182
>gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]
Length = 773
Score = 38.9 bits (89), Expect = 0.007
Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 9/102 (8%)
Query: 17 PSIEQMLAANPGKTPISLLQEYGTRIGKT-PVYDLLKAEGQAHQPNFTFRVTV-GDTSCT 74
P+ ++ + GK+ + +L EY R+ K PVY+ + E + F VT+ G T +
Sbjct: 498 PTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEP--FGASVTIDGVTYGS 555
Query: 75 GQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDS 116
G SKK AK+KAA L+ L + ++ +S P DS
Sbjct: 556 GTASSKKLAKNKAARATLEIL-----IPDFVKQTSEEKPKDS 592
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 38.9 bits (89), Expect = 0.007
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 159 NPVGALQELVVQKGWRLPEYTVTQESGPAHRKEF 192
+PV AL E+ ++ W+ PE+ + +SGP HRK F
Sbjct: 2371 HPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHF 2404
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 35.4 bits (80), Expect = 0.081
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 35 LQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTV-GDTSCTGQGPSKKAAKHKAAEVALK 93
L Y + G Y L G H FTF+V + G G+G SKK AK+ AA++A++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 94 HL 95
L
Sbjct: 74 IL 75
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,329,339
Number of Sequences: 37866
Number of extensions: 737472
Number of successful extensions: 2325
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 2029
Number of HSP's gapped (non-prelim): 292
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.