Guide to the Human Genome
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Search of human proteins with 197382649

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197382649 eukaryotic translation initiation factor 4E family
member 3 isoform b [Homo sapiens]
         (118 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197382708 eukaryotic translation initiation factor 4E family ...   245   5e-66
gi|197382664 eukaryotic translation initiation factor 4E family ...   245   5e-66
gi|197382649 eukaryotic translation initiation factor 4E family ...   245   5e-66
gi|27659734 eukaryotic translation initiation factor 4E family m...   245   5e-66
gi|4757702 eukaryotic translation initiation factor 4E member 2 ...    69   6e-13
gi|194578907 eukaryotic translation initiation factor 4E isoform...    54   2e-08
gi|4503535 eukaryotic translation initiation factor 4E isoform 1...    54   2e-08
gi|169211405 PREDICTED: similar to hCG1777996 [Homo sapiens]           54   2e-08
gi|169211874 PREDICTED: similar to hCG1777996 [Homo sapiens]           54   2e-08
gi|169210992 PREDICTED: hypothetical protein LOC100131693 [Homo ...    54   2e-08
gi|150378456 eukaryotic translation initiation factor 4E family ...    49   8e-07
gi|194578909 eukaryotic translation initiation factor 4E isoform...    40   4e-04
gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p...    27   2.6  
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ...    27   2.6  
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s...    27   2.6  
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ...    27   2.6  
gi|31377705 centrosomal protein 97kDa [Homo sapiens]                   27   4.5  
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H...    26   7.7  
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H...    26   7.7  
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho...    26   7.7  
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho...    26   7.7  
gi|153792012 DNA polymerase zeta [Homo sapiens]                        26   7.7  

>gi|197382708 eukaryotic translation initiation factor 4E family
           member 3 isoform a [Homo sapiens]
          Length = 224

 Score =  245 bits (626), Expect = 5e-66
 Identities = 118/118 (100%), Positives = 118/118 (100%)

Query: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
           MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 107 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 166

Query: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
           SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 167 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 224


>gi|197382664 eukaryotic translation initiation factor 4E family
           member 3 isoform b [Homo sapiens]
          Length = 118

 Score =  245 bits (626), Expect = 5e-66
 Identities = 118/118 (100%), Positives = 118/118 (100%)

Query: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
           MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60

Query: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
           SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118


>gi|197382649 eukaryotic translation initiation factor 4E family
           member 3 isoform b [Homo sapiens]
          Length = 118

 Score =  245 bits (626), Expect = 5e-66
 Identities = 118/118 (100%), Positives = 118/118 (100%)

Query: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
           MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60

Query: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
           SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118


>gi|27659734 eukaryotic translation initiation factor 4E family
           member 3 isoform b [Homo sapiens]
          Length = 118

 Score =  245 bits (626), Expect = 5e-66
 Identities = 118/118 (100%), Positives = 118/118 (100%)

Query: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
           MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1   MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60

Query: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
           SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61  SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118


>gi|4757702 eukaryotic translation initiation factor 4E member 2
           [Homo sapiens]
          Length = 245

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 15/117 (12%)

Query: 6   RPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR 65
           +P+WE+++N  GG W +++ K   S  W+ L+LA +GEQF       +E+ G  VSVR +
Sbjct: 121 KPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQF----MVGEEICGAVVSVRFQ 176

Query: 66  EDVVQVWNVNASLVGEAT------VLEKIYELLPHITFKAVFYKPHEEHHAFEGGRG 116
           ED++ +WN  AS   +AT       L ++  L P+   +   YK H +     G  G
Sbjct: 177 EDIISIWNKTAS--DQATTARIRDTLRRVLNLPPNTIME---YKTHTDSIKMPGRLG 228


>gi|194578907 eukaryotic translation initiation factor 4E isoform 3
           [Homo sapiens]
          Length = 237

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 7   PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
           P+WE+E N +GG W + + K    +     W E LL  IGE F D +   D+V G  V+V
Sbjct: 120 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 176

Query: 63  RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
           R + D + +W          T + ++Y+    +  K V  Y+ H +     G   K+
Sbjct: 177 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 233


>gi|4503535 eukaryotic translation initiation factor 4E isoform 1
           [Homo sapiens]
          Length = 217

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 7   PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
           P+WE+E N +GG W + + K    +     W E LL  IGE F D +   D+V G  V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156

Query: 63  RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
           R + D + +W          T + ++Y+    +  K V  Y+ H +     G   K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213


>gi|169211405 PREDICTED: similar to hCG1777996 [Homo sapiens]
          Length = 217

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 7   PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
           P+WE+E N +GG W + + K    +     W E LL  IGE F D +   D+V G  V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156

Query: 63  RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
           R + D + +W          T + ++Y+    +  K V  Y+ H +     G   K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213


>gi|169211874 PREDICTED: similar to hCG1777996 [Homo sapiens]
          Length = 217

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 7   PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
           P+WE+E N +GG W + + K    +     W E LL  IGE F D +   D+V G  V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156

Query: 63  RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
           R + D + +W          T + ++Y+    +  K V  Y+ H +     G   K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213


>gi|169210992 PREDICTED: hypothetical protein LOC100131693 [Homo
           sapiens]
          Length = 217

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 7   PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
           P+WE+E N +GG W + + K    +     W E LL  IGE F D +   D+V G  V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156

Query: 63  RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
           R + D + +W          T + ++Y+    +  K V  Y+ H +     G   K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213


>gi|150378456 eukaryotic translation initiation factor 4E family
           member 1B [Homo sapiens]
          Length = 242

 Score = 48.9 bits (115), Expect = 8e-07
 Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 8/107 (7%)

Query: 6   RPLWEEESNAKGGVWKMKVPKD----STSTVWKELLLATIGEQFTDCAAADDEVIGVSVS 61
           +P+WE+  N +GG W + + K         +W E LL  IGE F + +    EV G  V+
Sbjct: 124 QPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSR---EVCGAVVN 180

Query: 62  VRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEE 107
           +R + D + VW   A        + ++Y+    ++ K +  Y+ H +
Sbjct: 181 IRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHAD 227


>gi|194578909 eukaryotic translation initiation factor 4E isoform 2
           [Homo sapiens]
          Length = 248

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 34/148 (22%), Positives = 55/148 (37%), Gaps = 39/148 (26%)

Query: 7   PLWEEESNAKGGVWKMKVPKDS----------------------TSTVWKEL-------- 36
           P+WE+E N +GG W + + K                         S  W ++        
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPK 159

Query: 37  -----LLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIYEL 91
                LL  IGE F D +   D+V G  V+VR + D + +W          T + ++Y+ 
Sbjct: 160 VLELQLLCLIGESFDDYS---DDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKE 216

Query: 92  LPHITFKAVF-YKPHEEHHAFEGGRGKH 118
              +  K V  Y+ H +     G   K+
Sbjct: 217 RLGLPPKIVIGYQSHADTATKSGSTTKN 244


>gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
            protein 3 [Homo sapiens]
          Length = 2177

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 6/43 (13%)

Query: 58   VSVSVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAV 100
            +SVSVRD E  +Q W  N  L    TVL +I ++LP  TF A+
Sbjct: 2102 LSVSVRDAEAQIQAW-TNMVL----TVLNQI-QILPDQTFTAL 2138


>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
           sapiens]
          Length = 1723

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)

Query: 3   GERRPLWEEESNAKGGVWKMKVPKDSTST 31
           G R P WEEE +  GGVW     + S S+
Sbjct: 953 GARHPSWEEEED--GGVWNTTGSQGSASS 979


>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
           sapiens]
          Length = 1029

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)

Query: 3   GERRPLWEEESNAKGGVWKMKVPKDSTST 31
           G R P WEEE +  GGVW     + S S+
Sbjct: 259 GARHPSWEEEED--GGVWNTTGSQGSASS 285


>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
            sapiens]
          Length = 1833

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)

Query: 3    GERRPLWEEESNAKGGVWKMKVPKDSTST 31
            G R P WEEE +  GGVW     + S S+
Sbjct: 1006 GARHPSWEEEED--GGVWNTTGSQGSASS 1032


>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
          Length = 865

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 15/45 (33%), Positives = 21/45 (46%)

Query: 35  ELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLV 79
           EL L  I     D   AD+ V G+   V D+E+   +W  N + V
Sbjct: 420 ELRLQGINLGLEDDGVADESVKGLESQVLDKEEEQPLWAANENSV 464


>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
           sapiens]
          Length = 1205

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)

Query: 27  DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
           D T  V+K    A  GE+  +  A +DEV+  + S  DR       +  V++WN   S+ 
Sbjct: 636 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 688

Query: 80  GE 81
           GE
Sbjct: 689 GE 690


>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
           sapiens]
          Length = 1248

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)

Query: 27  DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
           D T  V+K    A  GE+  +  A +DEV+  + S  DR       +  V++WN   S+ 
Sbjct: 636 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 688

Query: 80  GE 81
           GE
Sbjct: 689 GE 690


>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
           sapiens]
          Length = 1194

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)

Query: 27  DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
           D T  V+K    A  GE+  +  A +DEV+  + S  DR       +  V++WN   S+ 
Sbjct: 625 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 677

Query: 80  GE 81
           GE
Sbjct: 678 GE 679


>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
           sapiens]
          Length = 1237

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)

Query: 27  DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
           D T  V+K    A  GE+  +  A +DEV+  + S  DR       +  V++WN   S+ 
Sbjct: 625 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 677

Query: 80  GE 81
           GE
Sbjct: 678 GE 679


>gi|153792012 DNA polymerase zeta [Homo sapiens]
          Length = 3130

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 11/26 (42%), Positives = 16/26 (61%)

Query: 83  TVLEKIYELLPHITFKAVFYKPHEEH 108
           T++++I ELL        FY+PHE H
Sbjct: 131 TMVKRICELLQSGAIMNKFYQPHEAH 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,597,119
Number of Sequences: 37866
Number of extensions: 165808
Number of successful extensions: 349
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 314
Number of HSP's gapped (non-prelim): 29
length of query: 118
length of database: 18,247,518
effective HSP length: 88
effective length of query: 30
effective length of database: 14,915,310
effective search space: 447459300
effective search space used: 447459300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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