Search of human proteins with 197313714

Search of human proteins with 197313714

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197313714 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 1 [Homo sapiens]
         (77 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197313714 sparc/osteonectin, cwcv and kazal-like domains prot...   161   1e-40
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo...   133   3e-32
gi|93141001 testican 3 isoform 2 [Homo sapiens]                        51   2e-07
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        50   4e-07
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo...    46   7e-06
gi|55741677 SET domain containing 1A [Homo sapiens]                    29   0.93 
gi|222080060 Smith-Magenis syndrome chromosome region, candidate...    27   3.5  
gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5 [...    27   3.5  
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    27   3.5  
gi|110556629 transmembrane protein 145 [Homo sapiens]                  27   4.6  
gi|122939161 peptidyl arginine deiminase, type III [Homo sapiens]      26   7.9  
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]        26   7.9  
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]        26   7.9  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...    26   7.9  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...    26   7.9  
gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]    26   7.9  

>gi|197313714 sparc/osteonectin, cwcv and kazal-like domains
          proteoglycan (testican) 2 isoform 1 [Homo sapiens]
          Length = 77

 Score =  161 bits (407), Expect = 1e-40
 Identities = 77/77 (100%), Positives = 77/77 (100%)

Query: 1  MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
          MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
Sbjct: 1  MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60

Query: 61 FRDVPSSDPPSTTQATP 77
          FRDVPSSDPPSTTQATP
Sbjct: 61 FRDVPSSDPPSTTQATP 77


>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
          proteoglycan (testican) 2 isoform 2 [Homo sapiens]
          Length = 424

 Score =  133 bits (335), Expect = 3e-32
 Identities = 64/68 (94%), Positives = 64/68 (94%)

Query: 1  MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
          MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
Sbjct: 1  MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60

Query: 61 FRDVPSSD 68
          FRD    D
Sbjct: 61 FRDEVEDD 68


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score = 50.8 bits (120), Expect = 2e-07
 Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 3/51 (5%)

Query: 18 AAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDVPSSD 68
          AAA A   A G  +G   GNF++D+QWL++ISQY  ++  WN+FRD    D
Sbjct: 21 AAAAAVAAAGGRSDG---GNFLDDKQWLTTISQYDKEVGQWNKFRDEVEDD 68


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 23/46 (50%), Positives = 32/46 (69%), Gaps = 3/46 (6%)

Query: 18 AAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63
          AAA A   A G  +G   GNF++D+QWL++ISQY  ++  WN+FRD
Sbjct: 21 AAAAAVAAAGGRSDG---GNFLDDKQWLTTISQYDKEVGQWNKFRD 63


>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
          proteoglycan 1 precursor [Homo sapiens]
          Length = 439

 Score = 45.8 bits (107), Expect = 7e-06
 Identities = 26/60 (43%), Positives = 36/60 (60%), Gaps = 10/60 (16%)

Query: 13 LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63
          + +LAAAA A           DA     G   GNF++++QWLS++SQY  + K+WNRFRD
Sbjct: 4  IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 15/61 (24%), Positives = 25/61 (40%)

Query: 17  AAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDVPSSDPPSTTQAT 76
           AA A +   +  L    +  +     Q+ SS + Y    + WNR++   S  P   T+  
Sbjct: 332 AATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREE 391

Query: 77  P 77
           P
Sbjct: 392 P 392


>gi|222080060 Smith-Magenis syndrome chromosome region, candidate 7
           isoform 3 [Homo sapiens]
          Length = 205

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 5/46 (10%)

Query: 4   PGCGRLVLPLLLLAAAALAEGDAKGLKEG-----ETPGNFMEDEQW 44
           P    L  P+L LA ++ A G+A GL+ G      +PG F +   W
Sbjct: 84  PPPAALSQPVLPLAPSSSAPGEAAGLRAGPCDHPSSPGGFGQTAGW 129


>gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5
           [Homo sapiens]
          Length = 678

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 29  LKE-GETPGNFMEDEQWLSSISQYSGKIKHWNRFRDVPSSDP 69
           LKE GE     +E + WL  +S+   +++HW   ++V +  P
Sbjct: 388 LKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSP 429


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
            sapiens]
          Length = 2564

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 29   LKE-GETPGNFMEDEQWLSSISQYSGKIKHWNRFRDVPSSDP 69
            LKE GE     +E + WL  +S+   +++HW   ++V +  P
Sbjct: 1712 LKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSP 1753


>gi|110556629 transmembrane protein 145 [Homo sapiens]
          Length = 493

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 1  MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWL 45
          +RAP   RL+ PLLLL  +      AK ++     GN    E W+
Sbjct: 4  LRAPALRRLLPPLLLLLLSLPPRARAKYVR-----GNLSSKEDWV 43


>gi|122939161 peptidyl arginine deiminase, type III [Homo sapiens]
          Length = 664

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

Query: 31  EGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDVPSSD 68
           EG    NF++  QW+   S Y G I   N  RD PS D
Sbjct: 126 EGRQDRNFVDKRQWVWGPSGYGG-ILLVNCDRDDPSCD 162


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 12 PLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSIS 49
          PLLLL   ALA   A GL+ G  PG +    +W  + S
Sbjct: 13 PLLLLLLLALA-ARADGLEFGGGPGQWARYARWAGAAS 49


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 12 PLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSIS 49
          PLLLL   ALA   A GL+ G  PG +    +W  + S
Sbjct: 13 PLLLLLLLALA-ARADGLEFGGGPGQWARYARWAGAAS 49


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
          sapiens]
          Length = 792

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 2  RAPGCGRLVLPLLLLAAAALAEG 24
          R PG  RL+L LLLLAA  +  G
Sbjct: 7  RGPGSQRLLLSLLLLAAWEVGSG 29


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
          sapiens]
          Length = 941

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 2  RAPGCGRLVLPLLLLAAAALAEG 24
          R PG  RL+L LLLLAA  +  G
Sbjct: 7  RGPGSQRLLLSLLLLAAWEVGSG 29


>gi|21313638 leucine-rich repeat LGI family, member 2 [Homo
          sapiens]
          Length = 545

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 1  MRAPGCGRLVLPLLLLAAAALAEGDAK 27
          +R  GCG L L LLLL AA L    A+
Sbjct: 3  LRRGGCGALGLLLLLLGAACLIPRSAQ 29


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,670,762
Number of Sequences: 37866
Number of extensions: 145037
Number of successful extensions: 266
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 254
Number of HSP's gapped (non-prelim): 16
length of query: 77
length of database: 18,247,518
effective HSP length: 49
effective length of query: 28
effective length of database: 16,392,084
effective search space: 458978352
effective search space used: 458978352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.