Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 195963412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195963412 transforming growth factor, beta receptor I
isoform 2 precursor [Homo sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195963412 transforming growth factor, beta receptor I isoform... 870 0.0
gi|4759226 transforming growth factor, beta receptor I isoform 1... 637 0.0
gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens] 589 e-168
gi|4757720 activin A receptor, type IB isoform a precursor [Homo... 579 e-165
gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens] 537 e-153
gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens] 537 e-153
gi|33598910 activin A receptor, type IB isoform b precursor [Hom... 511 e-145
gi|4502431 bone morphogenetic protein receptor, type IB precurso... 451 e-127
gi|41349437 bone morphogenetic protein receptor, type IA precurs... 436 e-122
gi|33598912 activin A receptor, type IB isoform c precursor [Hom... 429 e-120
gi|166235898 activin A receptor, type I precursor [Homo sapiens] 426 e-119
gi|4501895 activin A receptor, type I precursor [Homo sapiens] 426 e-119
gi|116734714 activin A receptor type II-like 1 [Homo sapiens] 406 e-113
gi|116734712 activin A receptor type II-like 1 [Homo sapiens] 406 e-113
gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens] 395 e-110
gi|67782324 transforming growth factor, beta receptor II isoform... 233 2e-61
gi|67782326 transforming growth factor, beta receptor II isoform... 233 2e-61
gi|4501897 activin A receptor, type IIA precursor [Homo sapiens] 232 6e-61
gi|116734708 activin A receptor, type IIB precursor [Homo sapiens] 221 1e-57
gi|15451916 bone morphogenetic protein receptor type II precurso... 196 3e-50
gi|10198656 anti-Mullerian hormone receptor, type II [Homo sapiens] 165 6e-41
gi|187475373 c-src tyrosine kinase [Homo sapiens] 95 1e-19
gi|4758078 c-src tyrosine kinase [Homo sapiens] 95 1e-19
gi|19526767 MLK-related kinase isoform 2 [Homo sapiens] 95 1e-19
gi|82880648 MLK-related kinase isoform 1 [Homo sapiens] 95 1e-19
gi|21735566 mitogen-activated protein kinase kinase kinase 7 iso... 85 1e-16
gi|21735564 mitogen-activated protein kinase kinase kinase 7 iso... 85 1e-16
gi|21735562 mitogen-activated protein kinase kinase kinase 7 iso... 85 1e-16
gi|4507361 mitogen-activated protein kinase kinase kinase 7 isof... 85 1e-16
gi|4506401 v-raf-1 murine leukemia viral oncogene homolog 1 [Hom... 84 2e-16
>gi|195963412 transforming growth factor, beta receptor I isoform 2
precursor [Homo sapiens]
Length = 426
Score = 870 bits (2247), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE 60
MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE
Sbjct: 1 MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE 60
Query: 61 TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGLPLLV 120
TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGLPLLV
Sbjct: 61 TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGLPLLV 120
Query: 121 QRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHE 180
QRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHE
Sbjct: 121 QRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHE 180
Query: 181 NILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLH 240
NILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLH
Sbjct: 181 NILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLH 240
Query: 241 MEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKR 300
MEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKR
Sbjct: 241 MEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKR 300
Query: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPS 360
YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPS
Sbjct: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPS 360
Query: 361 VEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQ 420
VEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQ
Sbjct: 361 VEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQ 420
Query: 421 QEGIKM 426
QEGIKM
Sbjct: 421 QEGIKM 426
>gi|4759226 transforming growth factor, beta receptor I isoform 1
precursor [Homo sapiens]
Length = 503
Score = 637 bits (1643), Expect = 0.0
Identities = 312/313 (99%), Positives = 313/313 (100%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ
Sbjct: 191 SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 250
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA
Sbjct: 251 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 310
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN
Sbjct: 311 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 370
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD
Sbjct: 371 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 430
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK
Sbjct: 431 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 490
Query: 414 TLSQLSQQEGIKM 426
TLSQLSQQEGIKM
Sbjct: 491 TLSQLSQQEGIKM 503
Score = 237 bits (605), Expect = 1e-62
Identities = 114/114 (100%), Positives = 114/114 (100%)
Query: 1 MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE 60
MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE
Sbjct: 1 MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE 60
Query: 61 TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTT 114
TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTT
Sbjct: 61 TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTT 114
>gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens]
Length = 413
Score = 589 bits (1519), Expect = e-168
Identities = 305/424 (71%), Positives = 340/424 (80%), Gaps = 16/424 (3%)
Query: 3 AAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT 62
A +A R LLLL AAAA L PG L+C C LC NFTC T+G C+ SV T
Sbjct: 4 ALCSALRQALLLL------AAAAELSPG---LKCVCLLCDSSNFTCQTEGACWASVMLTN 54
Query: 63 DKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPT-TGLPLLVQ 121
K C++ +P V SS +VT T CC D CN I L TGLPLLVQ
Sbjct: 55 GKEQVIKSCVS----LPELNAQVFCHSSN--NVTKTECCFTDFCNNITLHLPTGLPLLVQ 108
Query: 122 RTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHEN 181
RTIARTIVLQE +GKGRFGEVW G+W GE+VAVKIFSSR+ERSWFREAEIYQTVMLRHEN
Sbjct: 109 RTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHEN 168
Query: 182 ILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHM 241
ILGFIAADNKDNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS ASGLAHLHM
Sbjct: 169 ILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHM 228
Query: 242 EIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRY 301
EIVGTQGKPAIAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N +VGTKRY
Sbjct: 229 EIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRY 288
Query: 302 MAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSV 361
MAPE+LDD++N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD+VPSDPS+
Sbjct: 289 MAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSI 348
Query: 362 EEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQ 421
EEMRKVVC+QK RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKKT+SQL +
Sbjct: 349 EEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVK 408
Query: 422 EGIK 425
E K
Sbjct: 409 EDCK 412
>gi|4757720 activin A receptor, type IB isoform a precursor [Homo
sapiens]
Length = 505
Score = 579 bits (1492), Expect = e-165
Identities = 278/313 (88%), Positives = 297/313 (94%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPL VQRT+ARTIVLQE IGKGRFGEVWRG+WRG +VAVKIFSSREERSWFREAEIYQ
Sbjct: 193 SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQ 252
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT+EGMIKLALS A
Sbjct: 253 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAA 312
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKP IAHRDLKSKNILVKKNG C IADLGLAVRHD+ TDTIDIAPN
Sbjct: 313 SGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPN 372
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD++INMKHF+SFK ADIYA+GLV+WEIARRC+ GG+HE+YQLPYYD
Sbjct: 373 QRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYD 432
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
LVPSDPS+EEMRKVVC+QKLRPNIPN WQS EALRVM K+MRECWYANGAARLTALRIKK
Sbjct: 433 LVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKK 492
Query: 414 TLSQLSQQEGIKM 426
TLSQLS QE +K+
Sbjct: 493 TLSQLSVQEDVKI 505
Score = 75.5 bits (184), Expect = 9e-14
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Query: 2 EAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTET 61
E+A A+ L++L+LA + + G AL C C C + N+TC TDG C VS+
Sbjct: 3 ESAGASSFFPLVVLLLAGSGGSGPR---GVQALLCACTSCLQANYTCETDGACMVSIFNL 59
Query: 62 TDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
H CI +++L+P +PF C S + T+CC D+CN+I+L
Sbjct: 60 DGMEHHVRTCIPKVELVPAGKPFYCLSSE---DLRNTHCCYTDYCNRIDL 106
>gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens]
Length = 443
Score = 537 bits (1383), Expect = e-153
Identities = 259/312 (83%), Positives = 287/312 (91%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPLLVQRTIARTIVLQE +GKGRFGEVW G+W GE+VAVKIFSSR+ERSWFREAEIYQ
Sbjct: 131 SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQ 190
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS A
Sbjct: 191 TVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIA 250
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKPAIAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N
Sbjct: 251 SGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQN 310
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
+VGTKRYMAPE+LDD++N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD
Sbjct: 311 PKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYD 370
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VPSDPS+EEMRKVVC+QK RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKK
Sbjct: 371 MVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKK 430
Query: 414 TLSQLSQQEGIK 425
T+SQL +E K
Sbjct: 431 TISQLCVKEDCK 442
>gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens]
Length = 493
Score = 537 bits (1383), Expect = e-153
Identities = 259/312 (83%), Positives = 287/312 (91%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPLLVQRTIARTIVLQE +GKGRFGEVW G+W GE+VAVKIFSSR+ERSWFREAEIYQ
Sbjct: 181 SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQ 240
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS A
Sbjct: 241 TVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIA 300
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKPAIAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N
Sbjct: 301 SGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQN 360
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
+VGTKRYMAPE+LDD++N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD
Sbjct: 361 PKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYD 420
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VPSDPS+EEMRKVVC+QK RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKK
Sbjct: 421 MVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKK 480
Query: 414 TLSQLSQQEGIK 425
T+SQL +E K
Sbjct: 481 TISQLCVKEDCK 492
Score = 61.2 bits (147), Expect = 2e-09
Identities = 45/109 (41%), Positives = 53/109 (48%), Gaps = 15/109 (13%)
Query: 3 AAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT 62
A +A R LLLL AAAA L PG L+C C LC NFTC T+G C+ SV T
Sbjct: 4 ALCSALRQALLLL------AAAAELSPG---LKCVCLLCDSSNFTCQTEGACWASVMLTN 54
Query: 63 DKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
K C++ +P V SS +VT T CC D CN I L
Sbjct: 55 GKEQVIKSCVS----LPELNAQVFCHSS--NNVTKTECCFTDFCNNITL 97
>gi|33598910 activin A receptor, type IB isoform b precursor [Homo
sapiens]
Length = 476
Score = 511 bits (1315), Expect = e-145
Identities = 243/272 (89%), Positives = 259/272 (95%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPL VQRT+ARTIVLQE IGKGRFGEVWRG+WRG +VAVKIFSSREERSWFREAEIYQ
Sbjct: 193 SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQ 252
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT+EGMIKLALS A
Sbjct: 253 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAA 312
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKP IAHRDLKSKNILVKKNG C IADLGLAVRHD+ TDTIDIAPN
Sbjct: 313 SGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPN 372
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD++INMKHF+SFK ADIYA+GLV+WEIARRC+ GG+HE+YQLPYYD
Sbjct: 373 QRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYD 432
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCE 385
LVPSDPS+EEMRKVVC+QKLRPNIPN WQS E
Sbjct: 433 LVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYE 464
Score = 75.5 bits (184), Expect = 9e-14
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Query: 2 EAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTET 61
E+A A+ L++L+LA + + G AL C C C + N+TC TDG C VS+
Sbjct: 3 ESAGASSFFPLVVLLLAGSGGSGPR---GVQALLCACTSCLQANYTCETDGACMVSIFNL 59
Query: 62 TDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
H CI +++L+P +PF C S + T+CC D+CN+I+L
Sbjct: 60 DGMEHHVRTCIPKVELVPAGKPFYCLSSE---DLRNTHCCYTDYCNRIDL 106
>gi|4502431 bone morphogenetic protein receptor, type IB precursor
[Homo sapiens]
Length = 502
Score = 451 bits (1161), Expect = e-127
Identities = 212/313 (67%), Positives = 259/313 (82%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPLLVQRTIA+ I + + IGKGR+GEVW GKWRGE+VAVK+F + EE SWFRE EIYQ
Sbjct: 190 SGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQ 249
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TV++RHENILGFIAAD K G+WTQL+L++DYHE+GSL+DYL T+ + M+KLA S+
Sbjct: 250 TVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSV 309
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGL HLH EI TQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAV+ S T+ +DI PN
Sbjct: 310 SGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPN 369
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYM PEVLD+S+N HF+S+ AD+Y+ GL+ WE+ARRC GGI E+YQLPY+D
Sbjct: 370 TRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHD 429
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
LVPSDPS E+MR++VC +KLRP+ PNRW S E LR M K+M ECW N A+RLTALR+KK
Sbjct: 430 LVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKK 489
Query: 414 TLSQLSQQEGIKM 426
TL+++S+ + IK+
Sbjct: 490 TLAKMSESQDIKL 502
Score = 32.7 bits (73), Expect = 0.64
Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 14/105 (13%)
Query: 24 AAALLPGATALQCFCHL-CTKD--NFTCVTDGLCFVSVTETTDKV-IHNSMCIA--EIDL 77
+ A P L+C CH C +D N C TDG CF + E + + S C+ D
Sbjct: 20 STAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDF 79
Query: 78 IPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGLPLLVQR 122
RD P P + + C ++ CNK PT LP L R
Sbjct: 80 QCRDTPI---PHQRR---SIECCTERNECNKDLHPT--LPPLKNR 116
>gi|41349437 bone morphogenetic protein receptor, type IA precursor
[Homo sapiens]
Length = 532
Score = 436 bits (1121), Expect = e-122
Identities = 203/313 (64%), Positives = 255/313 (81%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPLLVQRTIA+ I + +GKGR+GEVW GKWRGE+VAVK+F + EE SWFRE EIYQ
Sbjct: 220 SGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQ 279
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TV++RHENILGFIAAD K G+WTQL+L++DYHE+GSL+D+L T+ ++KLA S A
Sbjct: 280 TVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAA 339
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
GL HLH EI GTQGKPAIAHRDLKSKNIL+KKNG+CCIADLGLAV+ +S T+ +D+ N
Sbjct: 340 CGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLN 399
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD+S+N HF+ + ADIY+ GL+ WE+ARRC GGI E+YQLPYY+
Sbjct: 400 TRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYN 459
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VPSDPS E+MR+VVC ++LRP + NRW S E LR + K+M ECW N A+RLTALRIKK
Sbjct: 460 MVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKK 519
Query: 414 TLSQLSQQEGIKM 426
TL+++ + + +K+
Sbjct: 520 TLAKMVESQDVKI 532
Score = 36.2 bits (82), Expect = 0.058
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 7/83 (8%)
Query: 34 LQCFCH-LCTKD--NFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSS 90
L+C+C C D N TC+T+G CF + E +A + F C S
Sbjct: 59 LKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQ----GETTLASGCMKYEGSDFQCKDSP 114
Query: 91 KTGSVTTTYCCNQDHCNKIELPT 113
K T CC + CN+ PT
Sbjct: 115 KAQLRRTIECCRTNLCNQYLQPT 137
>gi|33598912 activin A receptor, type IB isoform c precursor [Homo
sapiens]
Length = 487
Score = 429 bits (1102), Expect = e-120
Identities = 206/229 (89%), Positives = 218/229 (95%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLPL VQRT+ARTIVLQE IGKGRFGEVWRG+WRG +VAVKIFSSREERSWFREAEIYQ
Sbjct: 193 SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQ 252
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT+EGMIKLALS A
Sbjct: 253 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAA 312
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLHMEIVGTQGKP IAHRDLKSKNILVKKNG C IADLGLAVRHD+ TDTIDIAPN
Sbjct: 313 SGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPN 372
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGG 342
RVGTKRYMAPEVLD++INMKHF+SFK ADIYA+GLV+WEIARRC+ GG
Sbjct: 373 QRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGG 421
Score = 75.5 bits (184), Expect = 9e-14
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Query: 2 EAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTET 61
E+A A+ L++L+LA + + G AL C C C + N+TC TDG C VS+
Sbjct: 3 ESAGASSFFPLVVLLLAGSGGSGPR---GVQALLCACTSCLQANYTCETDGACMVSIFNL 59
Query: 62 TDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
H CI +++L+P +PF C S + T+CC D+CN+I+L
Sbjct: 60 DGMEHHVRTCIPKVELVPAGKPFYCLSSE---DLRNTHCCYTDYCNRIDL 106
>gi|166235898 activin A receptor, type I precursor [Homo sapiens]
Length = 509
Score = 426 bits (1095), Expect = e-119
Identities = 203/305 (66%), Positives = 245/305 (80%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLP LVQRT+AR I L E +GKGR+GEVWRG W+GE VAVKIFSSR+E+SWFRE E+Y
Sbjct: 194 SGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYN 253
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIA+D + TQLWL++ YHE GSL+DYL T+ +++ LS A
Sbjct: 254 TVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIA 313
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLH+EI GTQGKPAIAHRDLKSKNILVKKNG CCIADLGLAV H +T+ +D+ N
Sbjct: 314 SGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNN 373
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD++I + F+S+KR DI+A GLV WE+ARR GI EDY+ P+YD
Sbjct: 374 PRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYD 433
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VP+DPS E+MRKVVC + RPNIPNRW S L +AK+M+ECWY N +ARLTALRIKK
Sbjct: 434 VVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKK 493
Query: 414 TLSQL 418
TL+++
Sbjct: 494 TLTKI 498
>gi|4501895 activin A receptor, type I precursor [Homo sapiens]
Length = 509
Score = 426 bits (1095), Expect = e-119
Identities = 203/305 (66%), Positives = 245/305 (80%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLP LVQRT+AR I L E +GKGR+GEVWRG W+GE VAVKIFSSR+E+SWFRE E+Y
Sbjct: 194 SGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYN 253
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TVMLRHENILGFIA+D + TQLWL++ YHE GSL+DYL T+ +++ LS A
Sbjct: 254 TVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIA 313
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
SGLAHLH+EI GTQGKPAIAHRDLKSKNILVKKNG CCIADLGLAV H +T+ +D+ N
Sbjct: 314 SGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNN 373
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD++I + F+S+KR DI+A GLV WE+ARR GI EDY+ P+YD
Sbjct: 374 PRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYD 433
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VP+DPS E+MRKVVC + RPNIPNRW S L +AK+M+ECWY N +ARLTALRIKK
Sbjct: 434 VVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKK 493
Query: 414 TLSQL 418
TL+++
Sbjct: 494 TLTKI 498
>gi|116734714 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 406 bits (1043), Expect = e-113
Identities = 195/306 (63%), Positives = 237/306 (77%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLP LVQRT+AR + L E +GKGR+GEVWRG W GE VAVKIFSSR+E+SWFRE EIY
Sbjct: 188 SGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYN 247
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TV+LRH+NILGFIA+D + TQLWL++ YHEHGSL+D+L R T+ ++LA+S A
Sbjct: 248 TVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAA 307
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
GLAHLH+EI GTQGKPAIAHRD KS+N+LVK N CCIADLGLAV H +D +DI N
Sbjct: 308 CGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNN 367
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD+ I FES+K DI+A GLV WEIARR + GI EDY+ P+YD
Sbjct: 368 PRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYD 427
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VP+DPS E+M+KVVC + P IPNR + L +A++MRECWY N +ARLTALRIKK
Sbjct: 428 VVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKK 487
Query: 414 TLSQLS 419
TL ++S
Sbjct: 488 TLQKIS 493
>gi|116734712 activin A receptor type II-like 1 [Homo sapiens]
Length = 503
Score = 406 bits (1043), Expect = e-113
Identities = 195/306 (63%), Positives = 237/306 (77%)
Query: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
+GLP LVQRT+AR + L E +GKGR+GEVWRG W GE VAVKIFSSR+E+SWFRE EIY
Sbjct: 188 SGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYN 247
Query: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
TV+LRH+NILGFIA+D + TQLWL++ YHEHGSL+D+L R T+ ++LA+S A
Sbjct: 248 TVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAA 307
Query: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
GLAHLH+EI GTQGKPAIAHRD KS+N+LVK N CCIADLGLAV H +D +DI N
Sbjct: 308 CGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNN 367
Query: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
RVGTKRYMAPEVLD+ I FES+K DI+A GLV WEIARR + GI EDY+ P+YD
Sbjct: 368 PRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYD 427
Query: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
+VP+DPS E+M+KVVC + P IPNR + L +A++MRECWY N +ARLTALRIKK
Sbjct: 428 VVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKK 487
Query: 414 TLSQLS 419
TL ++S
Sbjct: 488 TLQKIS 493
>gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens]
Length = 336
Score = 395 bits (1015), Expect = e-110
Identities = 189/234 (80%), Positives = 212/234 (90%)
Query: 192 DNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPA 251
DNGTWTQLWLVS+YHE GSL+DYLNR VTV GMIKLALS ASGLAHLHMEIVGTQGKPA
Sbjct: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
Query: 252 IAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI 311
IAHRD+KSKNILVKK TC IADLGLAV+HDS +TIDI N +VGTKRYMAPE+LDD++
Sbjct: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
Query: 312 NMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQ 371
N+ FESFKRADIY++GLV+WEIARRCS+GGI E+YQLPYYD+VPSDPS+EEMRKVVC+Q
Sbjct: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
Query: 372 KLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIK 425
K RP+IPN+WQSCEALRVM +IMRECWYANGAARLTALRIKKT+SQL +E K
Sbjct: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCK 335
Score = 61.2 bits (147), Expect = 2e-09
Identities = 45/109 (41%), Positives = 53/109 (48%), Gaps = 15/109 (13%)
Query: 3 AAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT 62
A +A R LLLL AAAA L PG L+C C LC NFTC T+G C+ SV T
Sbjct: 4 ALCSALRQALLLL------AAAAELSPG---LKCVCLLCDSSNFTCQTEGACWASVMLTN 54
Query: 63 DKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIEL 111
K C++ +P V SS +VT T CC D CN I L
Sbjct: 55 GKEQVIKSCVS----LPELNAQVFCHSS--NNVTKTECCFTDFCNNITL 97
>gi|67782324 transforming growth factor, beta receptor II isoform B
precursor [Homo sapiens]
Length = 567
Score = 233 bits (595), Expect = 2e-61
Identities = 123/299 (41%), Positives = 181/299 (60%), Gaps = 9/299 (3%)
Query: 128 IVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSSREERSWFREAEIYQTVMLRHEN 181
I L +GKGRF EV++ K + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 182 ILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHM 241
IL F+ A+ + Q WL++ +H G+L +YL R+ ++ E + KL S A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 242 EIVGTQGKPA--IAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTK 299
+ G+P I HRDLKS NILVK + TCC+ D GL++R D D+A + +VGT
Sbjct: 364 DHTPC-GRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTA 422
Query: 300 RYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDP 359
RYMAPEVL+ +N+++ ESFK+ D+Y+M LV WE+ RC+ G +DY+ P+ V P
Sbjct: 423 RYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHP 482
Query: 360 SVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 418
VE M+ V + RP IP+ W + + ++++ + + ECW + ARLTA + + S+L
Sbjct: 483 CVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSEL 541
>gi|67782326 transforming growth factor, beta receptor II isoform A
precursor [Homo sapiens]
Length = 592
Score = 233 bits (595), Expect = 2e-61
Identities = 123/299 (41%), Positives = 181/299 (60%), Gaps = 9/299 (3%)
Query: 128 IVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSSREERSWFREAEIYQTVMLRHEN 181
I L +GKGRF EV++ K + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 269 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 328
Query: 182 ILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHM 241
IL F+ A+ + Q WL++ +H G+L +YL R+ ++ E + KL S A G+AHLH
Sbjct: 329 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 388
Query: 242 EIVGTQGKPA--IAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTK 299
+ G+P I HRDLKS NILVK + TCC+ D GL++R D D+A + +VGT
Sbjct: 389 DHTPC-GRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTA 447
Query: 300 RYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDP 359
RYMAPEVL+ +N+++ ESFK+ D+Y+M LV WE+ RC+ G +DY+ P+ V P
Sbjct: 448 RYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHP 507
Query: 360 SVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 418
VE M+ V + RP IP+ W + + ++++ + + ECW + ARLTA + + S+L
Sbjct: 508 CVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSEL 566
>gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]
Length = 513
Score = 232 bits (591), Expect = 6e-61
Identities = 122/302 (40%), Positives = 191/302 (63%), Gaps = 6/302 (1%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ + L E +GRFG VW+ + E VAVKIF ++++SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVG 245
I A+ + LWL++ +HE GSL D+L V+ + +A + A GLA+LH +I G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 246 TQG--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMA 303
+ KPAI+HRD+KSKN+L+K N T CIAD GLA++ ++ D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 304 PEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIG-GIHEDYQLPYYDLVPSDPSVE 362
PEVL+ +IN + ++F R D+YAMGLV WE+A RC+ G ++Y LP+ + + PS+E
Sbjct: 368 PEVLEGAINFQR-DAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 363 EMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQE 422
+M++VV +K RP + + WQ + ++ + + ECW + ARL+A + + ++Q+ +
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT 486
Query: 423 GI 424
I
Sbjct: 487 NI 488
>gi|116734708 activin A receptor, type IIB precursor [Homo sapiens]
Length = 512
Score = 221 bits (563), Expect = 1e-57
Identities = 117/295 (39%), Positives = 186/295 (63%), Gaps = 7/295 (2%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ + L E +GRFG VW+ + + VAVKIF ++++SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVG 245
IAA+ + + +LWL++ +H+ GSL DYL +T + +A + + GL++LH ++
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 246 TQG---KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYM 302
+G KP+IAHRD KSKN+L+K + T +AD GLAVR + D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 303 APEVLDDSINMKHFESFKRADIYAMGLVFWEIARRC-SIGGIHEDYQLPYYDLVPSDPSV 361
APEVL+ +IN + ++F R D+YAMGLV WE+ RC + G ++Y LP+ + + PS+
Sbjct: 366 APEVLEGAINFQR-DAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 362 EEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLS 416
EE+++VV +K+RP I + W L + + ECW + ARL+A +++ +S
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVS 479
>gi|15451916 bone morphogenetic protein receptor type II precursor
[Homo sapiens]
Length = 1038
Score = 196 bits (499), Expect = 3e-50
Identities = 114/300 (38%), Positives = 176/300 (58%), Gaps = 11/300 (3%)
Query: 130 LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAAD 189
L E IG+GR+G V++G VAVK+FS +++ E IY+ ++ H+NI FI D
Sbjct: 205 LLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGD 264
Query: 190 NKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV-GTQ 247
+ + LV +Y+ +GSL YL+ +T +LA S GLA+LH E+ G
Sbjct: 265 ERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDH 324
Query: 248 GKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS----ATDTIDIAPNHRVGTKRYMA 303
KPAI+HRDL S+N+LVK +GTC I+D GL++R D A VGT RYMA
Sbjct: 325 YKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMA 384
Query: 304 PEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDP 359
PEVL+ ++N++ ES K+ D+YA+GL++WEI RC+ G +YQ+ + V + P
Sbjct: 385 PEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHP 444
Query: 360 SVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 418
+ E+M+ +V +K RP P W ++ A+R + + + +CW + ARLTA ++ +++L
Sbjct: 445 TFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAEL 504
>gi|10198656 anti-Mullerian hormone receptor, type II [Homo sapiens]
Length = 573
Score = 165 bits (418), Expect = 6e-41
Identities = 109/329 (33%), Positives = 176/329 (53%), Gaps = 21/329 (6%)
Query: 112 PTTGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEI 171
P +G V+ + + I +G VW G+ +G+ VA+K F R + E +
Sbjct: 187 PDSGRDWSVELQELPELCFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERAL 246
Query: 172 YQTVMLRHENILGFIAADNKDNGTWTQ-LWLVSDYHEHGSLFDYLNRYTVTVEGMIKLAL 230
Y+ L+H++I+ FI A G LV + H GSL YL +YT +++AL
Sbjct: 247 YELPGLQHDHIVRFITASRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMAL 306
Query: 231 STASGLAHLHMEI-VGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTID 289
S A GLA LH E Q KP IAHRDL S+N+L++++G+C I DLGLA+ T
Sbjct: 307 SLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPA 366
Query: 290 IAPNH--------RVGTKRYMAPEVLDDSINMKHF-ESFKRADIYAMGLVFWEIARRCSI 340
P GT+RYMAPE+LD +++++ + + +RADIY++ L+ WEI RC
Sbjct: 367 WTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCP- 425
Query: 341 GGIHED-----YQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRV--MAKI 393
+ D +QL Y + + P+ +E+ + +++ RP IP+ W+ C A + ++
Sbjct: 426 -DLRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWR-CFATDPDGLREL 483
Query: 394 MRECWYANGAARLTALRIKKTLSQLSQQE 422
+ +CW A+ ARLTA +++ L+ L+ +
Sbjct: 484 LEDCWDADPEARLTAECVQQRLAALAHPQ 512
>gi|187475373 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 95.1 bits (235), Expect = 1e-19
Identities = 80/300 (26%), Positives = 142/300 (47%), Gaps = 48/300 (16%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ + L ++IGKG FG+V G +RG +VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEG---MIKLALSTASGLAHLHME 242
+ ++ G L++V++Y GSL DYL +V G ++K +L + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYL--- 305
Query: 243 IVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYM 302
+G + HRDL ++N+LV ++ ++D GL S DT + ++
Sbjct: 306 ----EGNNFV-HRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKL-------PVKWT 353
Query: 303 APEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVE 362
APE L + K F + ++D+++ G++ WEI S G + ++P D+V P VE
Sbjct: 354 APEALRE----KKFST--KSDVWSFGILLWEI---YSFGRVPYP-RIPLKDVV---PRVE 400
Query: 363 EMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQE 422
+ K+ P + ++M+ CW+ + A R + L++++ L + E
Sbjct: 401 KGYKMDAPDGCPP-------------AVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHE 447
>gi|4758078 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 95.1 bits (235), Expect = 1e-19
Identities = 80/300 (26%), Positives = 142/300 (47%), Gaps = 48/300 (16%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ + L ++IGKG FG+V G +RG +VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEG---MIKLALSTASGLAHLHME 242
+ ++ G L++V++Y GSL DYL +V G ++K +L + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYL--- 305
Query: 243 IVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYM 302
+G + HRDL ++N+LV ++ ++D GL S DT + ++
Sbjct: 306 ----EGNNFV-HRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKL-------PVKWT 353
Query: 303 APEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVE 362
APE L + K F + ++D+++ G++ WEI S G + ++P D+V P VE
Sbjct: 354 APEALRE----KKFST--KSDVWSFGILLWEI---YSFGRVPYP-RIPLKDVV---PRVE 400
Query: 363 EMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQE 422
+ K+ P + ++M+ CW+ + A R + L++++ L + E
Sbjct: 401 KGYKMDAPDGCPP-------------AVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHE 447
>gi|19526767 MLK-related kinase isoform 2 [Homo sapiens]
Length = 455
Score = 94.7 bits (234), Expect = 1e-19
Identities = 86/300 (28%), Positives = 140/300 (46%), Gaps = 57/300 (19%)
Query: 132 ESIGKGRFGEVWRGKW--RGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF--IA 187
E+ G G FG V+R KW + +EVAVK E +EAEI +L H NI+ F +
Sbjct: 20 ENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQFYGVI 72
Query: 188 ADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT---VTVEGMIKLALSTASGLAHLHMEIV 244
+ + G +V++Y GSL+DY+N + ++ ++ A A G+ +LHME
Sbjct: 73 LEPPNYG------IVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME-- 124
Query: 245 GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAP 304
+ HRDLKS+N+++ +G I D G + H+ T VGT +MAP
Sbjct: 125 ---APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHM------SLVGTFPWMAP 175
Query: 305 EVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEM 364
EV+ + + D Y+ G+V WE+ R ++P+ L ++
Sbjct: 176 EVI------QSLPVSETCDTYSYGVVLWEMLTR----------EVPFKGL-----EGLQV 214
Query: 365 RKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 424
+V E+ R IP+ SC R A+++ +CW A+ R + +I L +S +
Sbjct: 215 AWLVVEKNERLTIPS---SCP--RSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSL 269
>gi|82880648 MLK-related kinase isoform 1 [Homo sapiens]
Length = 800
Score = 94.7 bits (234), Expect = 1e-19
Identities = 86/300 (28%), Positives = 140/300 (46%), Gaps = 57/300 (19%)
Query: 132 ESIGKGRFGEVWRGKW--RGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF--IA 187
E+ G G FG V+R KW + +EVAVK E +EAEI +L H NI+ F +
Sbjct: 20 ENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQFYGVI 72
Query: 188 ADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT---VTVEGMIKLALSTASGLAHLHMEIV 244
+ + G +V++Y GSL+DY+N + ++ ++ A A G+ +LHME
Sbjct: 73 LEPPNYG------IVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME-- 124
Query: 245 GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAP 304
+ HRDLKS+N+++ +G I D G + H+ T VGT +MAP
Sbjct: 125 ---APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHM------SLVGTFPWMAP 175
Query: 305 EVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEM 364
EV+ + + D Y+ G+V WE+ R ++P+ L ++
Sbjct: 176 EVI------QSLPVSETCDTYSYGVVLWEMLTR----------EVPFKGL-----EGLQV 214
Query: 365 RKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 424
+V E+ R IP+ SC R A+++ +CW A+ R + +I L +S +
Sbjct: 215 AWLVVEKNERLTIPS---SCP--RSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSL 269
>gi|21735566 mitogen-activated protein kinase kinase kinase 7
isoform D [Homo sapiens]
Length = 491
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/217 (29%), Positives = 101/217 (46%), Gaps = 30/217 (13%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ I ++E +G+G FG V + KWR ++VA+K S ER F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT----VTVEGMIKLALSTASGLAHLHM 241
A + LV +Y E GSL++ L+ T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 242 EIVGTQGKPAIAHRDLKSKNILVKKNGTCC-IADLGLAVRHDSATDTIDIAPNHRVGTKR 300
+ A+ HRDLK N+L+ GT I D G A I + G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 337
+MAPEV + S ++ D+++ G++ WE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>gi|21735564 mitogen-activated protein kinase kinase kinase 7
isoform C [Homo sapiens]
Length = 518
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/217 (29%), Positives = 101/217 (46%), Gaps = 30/217 (13%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ I ++E +G+G FG V + KWR ++VA+K S ER F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT----VTVEGMIKLALSTASGLAHLHM 241
A + LV +Y E GSL++ L+ T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 242 EIVGTQGKPAIAHRDLKSKNILVKKNGTCC-IADLGLAVRHDSATDTIDIAPNHRVGTKR 300
+ A+ HRDLK N+L+ GT I D G A I + G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 337
+MAPEV + S ++ D+++ G++ WE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>gi|21735562 mitogen-activated protein kinase kinase kinase 7
isoform B [Homo sapiens]
Length = 606
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/217 (29%), Positives = 101/217 (46%), Gaps = 30/217 (13%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ I ++E +G+G FG V + KWR ++VA+K S ER F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT----VTVEGMIKLALSTASGLAHLHM 241
A + LV +Y E GSL++ L+ T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 242 EIVGTQGKPAIAHRDLKSKNILVKKNGTCC-IADLGLAVRHDSATDTIDIAPNHRVGTKR 300
+ A+ HRDLK N+L+ GT I D G A I + G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 337
+MAPEV + S ++ D+++ G++ WE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>gi|4507361 mitogen-activated protein kinase kinase kinase 7 isoform
A [Homo sapiens]
Length = 579
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/217 (29%), Positives = 101/217 (46%), Gaps = 30/217 (13%)
Query: 126 RTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGF 185
+ I ++E +G+G FG V + KWR ++VA+K S ER F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 186 IAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT----VTVEGMIKLALSTASGLAHLHM 241
A + LV +Y E GSL++ L+ T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 242 EIVGTQGKPAIAHRDLKSKNILVKKNGTCC-IADLGLAVRHDSATDTIDIAPNHRVGTKR 300
+ A+ HRDLK N+L+ GT I D G A I + G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 301 YMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 337
+MAPEV + S ++ D+++ G++ WE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>gi|4506401 v-raf-1 murine leukemia viral oncogene homolog 1 [Homo
sapiens]
Length = 648
Score = 84.3 bits (207), Expect = 2e-16
Identities = 71/217 (32%), Positives = 108/217 (49%), Gaps = 28/217 (12%)
Query: 125 ARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFS----SREERSWFREAEIYQTVMLRHE 180
A ++L IG G FG V++GKW G +VAVKI + E+ FR E+ RH
Sbjct: 346 ASEVMLSTRIGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRN-EVAVLRKTRHV 403
Query: 181 NILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE--GMIKLALSTASGLAH 238
NIL F+ KDN L +V+ + E SL+ +L+ + +I +A TA G+ +
Sbjct: 404 NILLFMGYMTKDN-----LAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query: 239 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 298
LH + I HRD+KS NI + + T I D GLA + + + G+
Sbjct: 459 LHAK--------NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV--EQPTGS 508
Query: 299 KRYMAPEVLDDSINMKHFESFK-RADIYAMGLVFWEI 334
+MAPEV I M+ F ++D+Y+ G+V +E+
Sbjct: 509 VLWMAPEV----IRMQDNNPFSFQSDVYSYGIVLYEL 541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,934,944
Number of Sequences: 37866
Number of extensions: 703495
Number of successful extensions: 3298
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 318
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 2230
Number of HSP's gapped (non-prelim): 798
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.