Guide to the Human Genome
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Search of human proteins with 194394139

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]       1041   0.0  
gi|19923391 homeobox D3 [Homo sapiens]                                 32   1.7  
gi|166235163 nuclear fragile X mental retardation protein intera...    31   2.3  
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]            30   3.9  
gi|24111244 MAM domain containing glycosylphosphatidylinositol a...    30   3.9  
gi|42519916 forkhead box O3A [Homo sapiens]                            30   5.1  
gi|4503739 forkhead box O3A [Homo sapiens]                             30   5.1  
gi|39812378 RAN binding protein 9 [Homo sapiens]                       30   5.1  
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 30   5.1  
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 30   5.1  
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 30   5.1  
gi|24307873 zinc finger protein 651 [Homo sapiens]                     30   5.1  
gi|169163739 PREDICTED: hypothetical protein [Homo sapiens]            29   8.6  
gi|88957138 PREDICTED: hypothetical protein [Homo sapiens]             29   8.6  
gi|88953651 PREDICTED: hypothetical protein [Homo sapiens]             29   8.6  
gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo ...    29   8.6  
gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo s...    29   8.6  
gi|118918413 MICAL C-terminal like [Homo sapiens]                      29   8.6  
gi|157674354 WD repeat domain 72 [Homo sapiens]                        29   8.6  

>gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]
          Length = 496

 Score = 1041 bits (2693), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVE 60
           MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVE
Sbjct: 1   MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVE 60

Query: 61  GNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRW 120
           GNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRW
Sbjct: 61  GNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRW 120

Query: 121 LLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFI 180
           LLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFI
Sbjct: 121 LLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFI 180

Query: 181 PYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLL 240
           PYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLL
Sbjct: 181 PYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLL 240

Query: 241 NVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNG 300
           NVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNG
Sbjct: 241 NVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNG 300

Query: 301 VVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGL 360
           VVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGL
Sbjct: 301 VVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGL 360

Query: 361 RLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHD 420
           RLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHD
Sbjct: 361 RLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHD 420

Query: 421 SHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQP 480
           SHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQP
Sbjct: 421 SHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQP 480

Query: 481 QGLEPSELLGMLSNGS 496
           QGLEPSELLGMLSNGS
Sbjct: 481 QGLEPSELLGMLSNGS 496


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 35/154 (22%), Positives = 58/154 (37%), Gaps = 19/154 (12%)

Query: 32  QPPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRL 91
           QPPPPP T    +   P    P        N  S  A   ++++ ++P   +      + 
Sbjct: 118 QPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSA---TISKQIFPWMKESRQNSKQK 174

Query: 92  HLLLNTSVTCNDGSPAGYYLKESRG--SRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSS 149
           +       +C D SP G   K  R   +   L+ LE  ++ FNR  C  R   M  L++ 
Sbjct: 175 NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFH-FNRYLCRPRRVEMANLLNL 233

Query: 150 RD-------------WPRTRTGTGILSSQPEENP 170
            +             + + +   GIL S   ++P
Sbjct: 234 TERQIKIWFQNRRMKYKKDQKAKGILHSPASQSP 267


>gi|166235163 nuclear fragile X mental retardation protein
          interacting protein 1 [Homo sapiens]
          Length = 495

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 3/46 (6%)

Query: 33 PPPPPRTEAAPAAGQPVESF---PLDFTAVEGNMDSFMAQVKSLAQ 75
          PPPPP T + PAAG    S    P++  ++ G    F AQ+   AQ
Sbjct: 45 PPPPPLTSSLPAAGSKPSSESQPPMEAQSLPGAPPPFDAQILPGAQ 90


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 14/41 (34%), Positives = 19/41 (46%)

Query: 32   QPPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKS 72
            +PP  PR E         +S  L +T  EG  D F+ Q K+
Sbjct: 2299 EPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKN 2339



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%)

Query: 18   GGSEGRKTWRRRGQQPPPPPRT-EAAPAAGQPVESFPLDFTAVEGNMDSFMAQVK 71
            G +E R      G + PP PR  E          S  L +T  EG  DSF+ Q K
Sbjct: 1757 GTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK 1811



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 17/48 (35%), Positives = 20/48 (41%)

Query: 24   KTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVK 71
            KT  R    P  PPR           +S  L +T  EG  DSF+ Q K
Sbjct: 1662 KTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFK 1709


>gi|24111244 MAM domain containing glycosylphosphatidylinositol
           anchor 1 [Homo sapiens]
          Length = 955

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 7/84 (8%)

Query: 4   GVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAV---- 59
           G  VLL  SLL  +        WR +GQ  PPPP     PAA +  +   L   AV    
Sbjct: 553 GRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPP---VVPAAAEAPDHAELRLDAVTRDS 609

Query: 60  EGNMDSFMAQVKSLAQSLYPCSAQ 83
            G+ +  ++     A  L+  SA+
Sbjct: 610 SGSYECSVSNDVGSAACLFQVSAK 633


>gi|42519916 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 15/32 (46%), Positives = 18/32 (56%)

Query: 17  AGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQP 48
           AGG  G      + QQP PPP+  AA  +GQP
Sbjct: 116 AGGLSGGTQALLQPQQPLPPPQPGAAGGSGQP 147


>gi|4503739 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 15/32 (46%), Positives = 18/32 (56%)

Query: 17  AGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQP 48
           AGG  G      + QQP PPP+  AA  +GQP
Sbjct: 116 AGGLSGGTQALLQPQQPLPPPQPGAAGGSGQP 147


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/16 (68%), Positives = 13/16 (81%)

Query: 33  PPPPPRTEAAPAAGQP 48
           PPPPP + AAPA+G P
Sbjct: 88  PPPPPASAAAPASGPP 103


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 10/24 (41%), Positives = 17/24 (70%)

Query: 26  WRRRGQQPPPPPRTEAAPAAGQPV 49
           W+++ QQPPPPP   ++ A+  P+
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPL 523


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 10/24 (41%), Positives = 17/24 (70%)

Query: 26  WRRRGQQPPPPPRTEAAPAAGQPV 49
           W+++ QQPPPPP   ++ A+  P+
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPL 523


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 10/24 (41%), Positives = 17/24 (70%)

Query: 26  WRRRGQQPPPPPRTEAAPAAGQPV 49
           W+++ QQPPPPP   ++ A+  P+
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPL 523


>gi|24307873 zinc finger protein 651 [Homo sapiens]
          Length = 371

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 13/63 (20%)

Query: 18 GGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSL 77
          G  E  +  RR G++P PPP   +A A G P               D   A+VK   +  
Sbjct: 13 GTPEPEEAGRRGGKRPKPPPGVASASARGPPA-------------TDGLGAKVKLEEKQH 59

Query: 78 YPC 80
          +PC
Sbjct: 60 HPC 62


>gi|169163739 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 125

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 14/36 (38%), Positives = 18/36 (50%)

Query: 12 SLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQ 47
          S+    GGS  R++  RRGQ P    + E AP   Q
Sbjct: 41 SVARSGGGSNRRRSRERRGQNPASLAQGEVAPVGAQ 76


>gi|88957138 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 125

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 14/36 (38%), Positives = 18/36 (50%)

Query: 12 SLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQ 47
          S+    GGS  R++  RRGQ P    + E AP   Q
Sbjct: 41 SVARSGGGSNRRRSRERRGQNPASLAQGEVAPVGAQ 76


>gi|88953651 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 125

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 14/36 (38%), Positives = 18/36 (50%)

Query: 12 SLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQ 47
          S+    GGS  R++  RRGQ P    + E AP   Q
Sbjct: 41 SVARSGGGSNRRRSRERRGQNPASLAQGEVAPVGAQ 76


>gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 594

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 13/49 (26%), Positives = 23/49 (46%)

Query: 443 PHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQGLEPSELLGM 491
           P C+    T+       ++ V  FL   G  M++  +   L P++LLG+
Sbjct: 349 PLCSQGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGL 397


>gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 439

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 13/49 (26%), Positives = 23/49 (46%)

Query: 443 PHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQGLEPSELLGM 491
           P C+    T+       ++ V  FL   G  M++  +   L P++LLG+
Sbjct: 349 PLCSQGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGL 397


>gi|118918413 MICAL C-terminal like [Homo sapiens]
          Length = 695

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 16/55 (29%), Positives = 22/55 (40%)

Query: 33  PPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNE 87
           PPPPP      A G   ++FPL     E +  +      S  +   P  + QL E
Sbjct: 461 PPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKE 515


>gi|157674354 WD repeat domain 72 [Homo sapiens]
          Length = 1102

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 16/59 (27%), Positives = 29/59 (49%)

Query: 44  AAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCN 102
           A G+ + +  +     +G+   +      L++S+YP   + L E +  HLL +TSV  N
Sbjct: 259 AGGEVIAAHRILIWTEDGHSYIYQLLNSGLSKSIYPADGRVLKETIYPHLLCSTSVQEN 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,140,169
Number of Sequences: 37866
Number of extensions: 1033144
Number of successful extensions: 4929
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4859
Number of HSP's gapped (non-prelim): 69
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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